RA0187

antibody from Oursmab

Targeting: H2AC4 H2A/m, H2AFM, HIST1H2AB

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0187

Provider

Oursmab

Product name

Derlotuximab (Biosimilar Reference Antibody) (DNA)

Antibody type

Monoclonal

Description

Derlotuximab is a recombinant human monoclonal antibody engineered as a targeted therapy for glioblastoma (GBM) and other solid tumors. It is designed to specifically bind to an intracellular antigen¡ªDNA/histone (H1) complexes¡ªthat becomes exposed in the necrotic core of aggressive tumors. This unique targeting strategy allows the antibody to deliver a therapeutic payload (such as a radioactive isotope) directly to the tumor site, sparing healthy tissues. It has been investigated in clinical trials, including advanced phases, for the treatment of recurrent or newly diagnosed GBM.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,279 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

store at -20¡ãC or -80¡ãC. Avoid repeated freeze.