ABIN2841626

antibody from antibodies-online

Targeting: CDK8 K35

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2841626

Provider

antibodies-online

Product name

anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 1-30), (N-Term) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 1-30, N-Term

Antibody clone number

RB3200

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

TFIIH is negatively regulated by cdk8-containing mediator complexes.

Akoulitchev S, Chuikov S, Reinberg D
Nature 2000 Sep 7;407(6800):102-6

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Genomics of the human genes encoding four TAFII subunits of TFIID, the three subunits of TFIIA, as well as CDK8 and SURB7.

Di Pietro C, Rapisarda A, Bonaiuto C, Lizzio MN, Engel H, Amico V, Scalia M, Amato A, Grzeschik KH, Sichel G, Purrello M
Somatic cell and molecular genetics 1999 May;25(3):185-9

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Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases.

Rickert P, Corden JL, Lees E
Oncogene 1999 Jan 28;18(4):1093-102

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Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C.

Tassan JP, Jaquenoud M, Léopold P, Schultz SJ, Nigg EA
Proceedings of the National Academy of Sciences of the United States of America 1995 Sep 12;92(19):8871-5

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB