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- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 22067-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CDK8 antibody
- Antibody type
- Polyclonal
- Description
- CDK8 antibody (Cat. #22067-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PP2A and its adapter protein IER5 induce the DNA-binding ability and target gene expression of E2F1 via dephosphorylation at serine 375.
Knockdown of Long Noncoding RNA CCAT2 Suppresses Malignant Phenotype in Human Laryngeal Squamous Cell Carcinoma.
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.
Takeuchi H, Koga M, Doi K, Sakurai H
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Sep;1866(3):194960
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Sep;1866(3):194960
Knockdown of Long Noncoding RNA CCAT2 Suppresses Malignant Phenotype in Human Laryngeal Squamous Cell Carcinoma.
Li M, An J, Ren H, Gui J, Wang H, Wu S, Wu R, Xiao H, Wang L
Bulletin of experimental biology and medicine 2023 Sep;175(5):673-680
Bulletin of experimental biology and medicine 2023 Sep;175(5):673-680
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Jackson LM, Dhoonmoon A, Hale A, Dennis KA, Schleicher EM, Nicolae CM, Moldovan GL
Nucleic acids research 2021 Dec 16;49(22):12855-12869
Nucleic acids research 2021 Dec 16;49(22):12855-12869
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.
Schleicher EM, Dhoonmoon A, Jackson LM, Clements KE, Stump CL, Nicolae CM, Moldovan GL
PLoS genetics 2020 Nov;16(11):e1009176
PLoS genetics 2020 Nov;16(11):e1009176
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 22067-1-AP(CDK8 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 22067-1-AP(CDK8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDK8 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CDK8. This antibody recognizes human, mouse antigen. The CDK8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
