abx001900

antibody from Abbexa

Targeting: UHRF1 FLJ21925, ICBP90, Np95, RNF106, TDRD22

Western blot

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: abx001900 - Provider product page
Provider: Abbexa
Product name: Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody
Antibody type: Polyclonal
Description: UHRF1 Antibody is a Rabbit Polyclonal antibody against UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µl
Concentration: > 1 mg/ml
Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

UHRF1 protein structure - abx001900 shown in red.