CABT-BL892

antibody from Creative Diagnostics

Targeting: CCL4 Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

CABT-BL892

Provider

Creative Diagnostics

Product name

Anti-CCL4 polyclonal antibody

Antibody type

Polyclonal

Description

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

-20°C, Avoid freeze / thaw cycles