Tissue expression
Cell line expression
Protein structure
H2AC8
H2A clustered histone 8H2A.1, H2A/a, H2AFA, HIST1H2AE
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Top validated antibodies |
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Novus Biologicals | ![]() |
Monoclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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ABEOMICS Inc. | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Monoclonal |
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