10968-1-AP

antibody from Proteintech Group

Targeting: NCOA4 ARA70, DKFZp762E1112, ELE1, PTC3, RFG

ELISA (Data presented on provider website)

Antibody Data

Product number

10968-1-AP

Provider

Proteintech Group

Product name

NCOA4 antibody

Antibody type

Polyclonal

Description

NCOA4 antibody (Cat. #10968-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Association Between Ferritinophagy and M1 Macrophage Polarization During the Acute Phase of Childhood Allergic Asthma.

Li J, Wang X, Shi X, Jiang Y, Shen R
Journal of inflammation research 2026;19:569956

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Dandelion (Taraxacum mongolicum Hand. -Mazz.) extract inhibits triple-negative breast cancer by inducing ferroptosis via NCOA4-mediated ferritinophagy.

Guo Z, Hao H, Deng X, Jiao Y, Dong B, Xue D, Han S
Journal of ethnopharmacology 2026 May 23;363:121393

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Subchronic exposure to decabromodiphenyl ethane impairs cognitive function and induces neuronal ferroptosis via disruption of mitochondria-associated endoplasmic reticulum membranes.

Sun Y, Xiong F, Wu L, Liu Z, Liu P, Li W, Zhang J, Sun R
Journal of hazardous materials 2026 May 15;509:142036

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FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.

Qin J, Ma S, Wang J, Huang S, Luan J, He J, Hou G, Sun N, Zhang W, Gao M
Cell death & disease 2026 Mar 20;17(1)

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BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression.

Zhao L, Peng Y, Liang Q, Liu S, Li Y, Ma L, Hu M, Zheng S, Liu Z, Gao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 15;:e21885

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RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.

Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610

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RBX1 mitigates ferroptosis by inhibiting NCOA4-mediated ferritinophagy and contributes to the attenuation of intervertebral disc degeneration.

Zhou LP, Kang L, Zhang ZG, Jia CY, Zhao CH, Zhang XL, Zhang HQ, Zhang RJ, Shen CL
Journal of translational medicine 2025 May 7;23(1):514

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Dopamine Alleviated Diabetic Retinal Neurodegeneration through Protecting Retinal Ganglion Cells from Ferroptosis via the Nrf2/HO‑1 Signaling Pathway.

Rao S, Xiao K, Chen X, Sun X
ACS omega 2025 Jul 22;10(28):30397-30410

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Combination of astragalus polysaccharide with Diosbulbin B exerts an enhanced antitumor effect in BRAF(mut) papillary thyroid cancer with decreased liver toxicity.

Xu S, Liang Q, Li H, Zhou H, Xu Z, Yan Y, Zhang Y, Ye R, You X
Cancer cell international 2025 Jul 2;25(1):245

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Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.

Wu F, Song C, Yin H, Chen R, Huang G, Zhang J, Chen H, Lin L, Yin J, Xie L, Liu W
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113814

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Nrg4 Secreted by Brown Adipose Tissue Suppresses Ferroptosis of Sepsis-Induced Liver Injury.

Feng L, Cui J, Chen W, Zhu L, Li P, Zhou H, Sun Y, Yi W
Inflammation 2025 Aug;48(4):2783-2801

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IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.

Li Y, Jiang J, Zhuo Y, Li J, Li Y, Xia Y, Yu Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877

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NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.

Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343

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Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().

Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228

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Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.

Pan C, Wang K, Hong R, Wang X, Zhang Y, Fan Z, Shi Y, Liu T, Chen H
Environmental research 2024 Dec 15;263(Pt 2):120098

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Tetrastigma hemsleyanum polysaccharide combined with doxorubicin promote ferroptosis and immune function in triple-negative breast cancer.

Shang Y, Zhao M, Chen S, Chen Y, Liu X, Zhou F, Li Y, Long M, Xu K, Ding Z, Wang L
International journal of biological macromolecules 2024 Aug;275(Pt 1):133424

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Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.

Wang R, Li J, Fu Y, Li Y, Qi Y, Li C, Gao F, Li C
Biochemical pharmacology 2023 Dec;218:115874

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Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.

Li H, Zhou W, Wei H, Li L, Wang X, Li Y, Li S, Li C
Journal of oncology 2021;2021:3015710