Explore
Validate
Learn60143-1-Ig
antibody from Proteintech Group
Targeting: MRC1
bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [275]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 60143-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60143-1-Ig, RRID:AB_2144924
- Product name
- CD206 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated CD206 antibody (Cat. #60143-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A6A10
- Vial size
- 20ul, 150ul
Submitted references Microglial TIA1-mediated stress granules promote neuroinflammation and aggravate neuron loss in mice after ischemic stroke by inhibiting IGF2 signaling.
Kaempferol Suppresses Abdominal Aortic Aneurysm Development via Modulation of Macrophage Polarization Through the STAT/TNF Signaling Pathway.
SIRT3 alleviates periodontitis inflammation by inhibiting macrophage M1 polarization regulation via FOXO3/NRF2.
Reprogramming tumour-associated macrophages in breast cancer via si-FOXM1-loaded lipid nanoparticles enhances immune checkpoint inhibitor efficacy.
Vitamin E alleviates experimental autoimmune prostatitis by inhibiting the EGFR/MAPK pathway to reduce M1 macrophage polarization.
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Spatiotemporally Engineered Protein Delivery via Integrated Covalent Coupling and Pathological Triggers for Precision Microenvironment Reprogramming in Tissue Injury Repair.
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Sanmiao pill ameliorates rheumatoid arthritis via PPARγ-mediated lipid accumulation in macrophage: A multi-omics and experimental validation.
Hydrogel with cell-cell adhesion cues enhances neural regeneration.
Extracellular vesicle-derived miRNA-182-5p educates macrophages towards an immunosuppressive phenotype in pancreatic cancer.
Hofbauer Cells in Pregnancies Complicated by Gestational Diabetes Mellitus and Pathological Fetal Growth.
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
SIX2-Mediated Microglial M2 Polarization and Exosomal miR-3470b Delivery Protect Dopaminergic Neurons in Parkinson's Disease.
Icariin alleviates corneal neovascularization by regulating inflammation through inhibition of macrophage polarization and the NF-κB pathway.
DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.
IPF AT2 cells are stuck in transition and biophysically dysfunctional.
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
Kif15 Orchestrates Neuronal-Microglial Communication via CX3CL1 to Impede Nerve Regeneration.
M2 type macrophages promote OSCC progress via conferring resistance to Erastin-induced ferroptosis.
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.
A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression.
Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury.
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation.
Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.
VSIG4 as a tumor-associated macrophage marker predicting adverse prognosis in diffuse large B-cell lymphoma.
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Nao-Xin-Qing tablet inhibits macrophage inflammatory response in atherosclerosis via AMPK-α/SIRT1/PPAR-γ pathway.
ANAPC5 mitigates acute lung injury through regulating macrophage M1/M2 polarization via the EGFR/CD24 axis.
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Moxibustion Alleviates Inflammation via SIRT5-mediated Post-translational Modification and Macrophage Polarization.
Engineering a placenta-inspired biomimicking fibrous patch for chondrogenesis through immunomodulation.
Co-assembled polypeptides-adsorbing bridge molecules to enhance macrophage efferocytosis for the resolution of periodontitis inflammation.
Slipknot-gauged mechanical transmission and robotic operation.
Co-treatment of ticagrelor and anti-PD-1 immunotherapy in tumor-associated macrophages reduces pancreatic cancer cell growth and migration through the TGF-β1/Smad2 pathway.
Microneedle-facilitated Portulaca oleracea L.-derived nanovesicles ameliorate atopic dermatitis by modulating macrophage M1/M2 polarization and inhibiting NF-κB and STING signaling pathways.
A mitochondria-targeted nanomedicine for myocardial ischemia/reperfusion injury with synergistic antioxidant and anti-inflammatory properties.
Procyanidin B2 alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the NF-κB/JAK2/STAT1 signaling pathway.
M2 macrophages and tumor cells engage in a metabolic feedback loop to drive HCC progression.
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Silk fibroin methacryloyl hydrogel loaded with silver-gallic acid nanoparticles for enhanced diabetic wound healing.
Potentilla anserina L. polysaccharide ameliorates LPS-induced acute lung injury and relevant intestinal mucosal barrier impairment.
INHBA, transcriptionally activated by SPI1, facilitates gastric cancer progression by inducing macrophage recruitment and M2 polarization via activating the TGF-β signaling to increase CCL2.
M2 macrophages-derived exosomal MDH1 drives lung adenocarcinoma progression via the Hippo/YAP signaling.
Anti-fibrotic, muscle-promoting antibody-drug conjugates for the improvement and treatment of DMD.
Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.
Comprehensive analysis reveals the prognostic and immunological role of PSMD13 in hepatocellular carcinoma.
Extracellular HSP70 facilitated β-glucan induced trained immunity in macrophages to suppress sepsis via TLR2-NF-κB axis.
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Apabetalone alleviates ligature-induced periodontitis by inhibiting M1 macrophage polarization via an immunometabolic shift.
Estrogen via GPER downregulated HIF-1a and MIF expression, attenuated cardiac arrhythmias, and myocardial inflammation during hypobaric hypoxia.
Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration.
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
TREM2 promotes hippocampal neurogenesis through regulating microglial M2 polarization in APP/PS1 mice.
Reducing degradation of EETs by sEH protein macromolecule depletion prevents MCAO and inhibits microglia-mediated inflammatory response.
Reprogramming Glucose Metabolism of Macrophage for Acute Liver Failure Therapy with Itaconate Lipo-Nanodrug.
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Integrating multi-omics data to optimize immunotherapy in endometrial cancer: a comprehensive study.
Integrative PANoptosis gene profiling reveals prognostic and therapeutic insights in prostate cancer.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
The Polarization of Macrophages Regulated by KCNG3 via the Activation of ASK1 Mediated by Potassium Ion Efflux.
Photosensitive Biomimetic Nanomedicine-Mediated Recombination of Adipose Microenvironments for Antiobesity Therapy.
Coriander-Derived Exosome-Like Nanovesicles Laden Hydrogel with Antioxidant Property Accelerates Wound Healing.
Liang-Ge-San drives macrophages toward M2 polarization for alleviating lipopolysaccharide-induced acute lung injury via activating the miR-21/PTEN axis.
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Immunomodulatory and osteogenic effects of chitosan-based injectable hydrogel with geniposide-loaded mesoporous bioactive glass.
Caffeic acid-vanadium nanozymes treat skin flap ischemia-reperfusion injury through macrophage reprogramming and the upregulation of X-linked inhibitors of apoptotic proteins.
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
Gastric cancer-derived exosomal let-7 g-5p mediated by SERPINE1 promotes macrophage M2 polarization and gastric cancer progression.
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Algae-inspired chitosan-pullulan-based multifunctional hydrogel for enhanced wound healing.
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Sodium butyrate attenuates microglia-mediated neuroinflammation by modulating the TLR4/MyD88/NF-κB pathway and microbiome-gut-brain axis in cardiac arrest mice.
IL-27 regulates macrophage ferroptosis by inhibiting the Nrf2/HO1 signaling pathway in sepsis-induced ARDS.
Catalpalactone protects rats nerve function from hypoxic lesion by polarizing microglial cells toward M2 phenotype.
SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma cells.
PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study.
Genetic Ablation of miR-146a Induces Abdominal Aortic Aneurysm Formation by Intensifying Inflammatory M1-Like Macrophages Polarization and Vascular Smooth Muscle Cell Phenotypic Switching.
ERO1A-positive tumor epithelial cells in colorectal cancer progression: a multi-omics perspective.
Fungal β-glucan instructed miR-32-5p modulates Dectin-1 signaling mediated inflammation, reactive oxygen species and apoptosis through polarization of "M2a-like" macrophage in Candida colitis.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
RICH1 enhances pro-inflammatory TAM infiltration in breast cancer via promoting TRIM21-mediated ubiquitination of RhoA and inhibiting STAT3 phosphorylation.
CCL8 suppresses ovarian cancer progression via M1 macrophage polarization and NF-κB-mediated apoptosis.
Pathology-oriented multiplexing enables integrative disease mapping.
Spatiotemporal Immunomodulation of Macrophages via NLRP3/IL-1β Pathway by Core-Shell Microneedles to Promote Healing of Biofilm-Infected Diabetic Ulcers.
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair.
Artemether ameliorates DSS-induced ulcerative colitis by modulating macrophage polarization.
Efficacy of electro-acupuncture at "Weizhong" (BL40) on macrophage polarization in rats with injured lumbar multifidus.
Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension.
Hybrid membranes-mediated biomimetic-nanoparticle carrying miR-665 for effective tumor treatment by remodeling tumor microenvironment.
Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages.
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
The Effect Mechanism of N6-adenosine Methylation (m6A) in Melatonin Regulated LPS-induced Colon Inflammation.
NLRP3 Inflammasome Inhibition After Pilocarpine-Induced Status Epilepticus Attenuates Chronic Inflammation in Epileptic Mice.
Urine-derived stem cells genetically modified with IGF1 improve muscle regeneration.
PLA2G2D promotes immune escape in non-small cell lung cancer by regulating T cell immune function through PD-L1-expressing extracellular vesicles.
Intratumoral microbiota as a novel prognostic indicator in bladder cancer.
SPP1 promotes the polarization of M2 macrophages through the Jak2/Stat3 signaling pathway and accelerates the progression of idiopathic pulmonary fibrosis.
Multifunctional Nanocomposite Hydrogel with Enhanced Chemodynamic Therapy and Starvation Therapy for Inhibiting Postoperative Tumor Recurrence.
Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation.
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
Distinct activation of M1 and M2 macrophages in the primary pterygium lymphangiogenesis.
A multifunctional self-reinforced injectable hydrogel for enhancing repair of infected bone defects by simultaneously targeting macrophages, bacteria, and bone marrow stromal cells.
Neutrophil-Driven M2-Like Macrophages Are Critical for Skin Fibrosis in a Systemic Sclerosis Model.
Ultrasound Stimulation Modulates Microglia M1/M2 Polarization and Affects Hippocampal Proteomic Changes in a Mouse Model of Alzheimer's Disease.
Nanocomposite Hydrogel for Real-Time Wound Status Monitoring and Comprehensive Treatment.
Mitochondrial transplantation following cardiopulmonary resuscitation improves neurological function in rats by inducing M2-type MG/MΦ polarization.
CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.
LncRNA CRNDE promotes hepatoma cell proliferation by regulating the metabolic reprogramming of M2 macrophages via ERK pathway.
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
Nicotine regulates abnormal macrophage polarization and trophoblast invasion associated with preterm labor via the α7nAChR/SIRT1 axis.
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression.
23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling.
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.
Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis.
In Situ Reaction-Generated Aldehyde-Scavenging Polypeptides-Curcumin Conjugate Nanoassemblies for Combined Treatment of Spinal Cord Injury.
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Multifunctional Biodegradable Conductive Hydrogel Regulating Microenvironment for Stem Cell Therapy Enhances the Nerve Tissue Repair.
Significance of dysregulated M2 macrophage and ESR2 in the ovarian metastasis of gastric cancer.
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
COL8A1 is a potential prognostic biomarker associated with migration, proliferation, and tumor microenvironment in glioma.
Nebulized platelet-derived extracellular vesicles attenuate chronic cigarette smoke-induced murine emphysema.
Bone marrow monocytes and macrophages from mice lacking βENaC and ASIC2 have a reduced chemotactic migration response and polarization.
Interaction pathways of implant metal localized corrosion and macrophage inflammatory reactions.
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Mechanical force increases tooth movement and promotes remodeling of alveolar bone defects augmented with bovine bone mineral.
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway.
Mannose-Integrated Nanoparticle Hitchhike Glucose Transporter 1 Recycling to Overcome Various Barriers of Oral Delivery for Alzheimer's Disease Therapy.
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
IL-34 attenuates acute T cell-mediated rejection following renal transplantation by upregulating M2 macrophages polarization.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Profibrogenic macrophage-targeted delivery of mitochondrial protector via exosome formula for alleviating pulmonary fibrosis.
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Modulation of microglial polarization by sequential targeting surface-engineered exosomes improves therapy for ischemic stroke.
Arginine-Nanoenzyme with Timely Angiogenesis for Promoting Diabetic Wound Healing.
The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats.
Sirt3-Mediated Opa1 Deacetylation Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Alveolar Macrophage Pro-Inflammatory Polarization.
Preparation of recombinant type I collagen (PF-I-80) and its functional characterization and biomedical applications in wound healing.
Phosphatidylserine-functional polydimethylsiloxane substrates regulate macrophage M2 polarization via modulus-dependent NF-κB/PPARγ pathway.
Swimming upregulates APOL3 through regulating macrophage polarization to inhibit glycolysis and the development of melanoma.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Biocompatible ionized air alleviates rat osteoarthritis by modulating polarization from M1 to M2 macrophages.
NIR-II Imaging for Tracking the Spatiotemporal Immune Microenvironment in Atherosclerotic Plaques.
Dendritic epidermal T cell hydrogel induces the polarization of M2 macrophages to promote the healing of deep tissue pressure injury.
Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis.
Melatonin regulates microglial M1/M2 polarization via AMPKα2-mediated mitophagy in attenuating sepsis-associated encephalopathy.
M2 macrophage-polarized anti-inflammatory microneedle patch for accelerating biofilm-infected diabetic wound healing via modulating the insulin pathway.
M2 macrophage-derived exosomes carry miR-142-3p to restore the differentiation balance of irradiated BMMSCs by targeting TGF-β1.
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case.
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma.
SMPDL3B contributes to gastric adenocarcinoma cells progression by promoting the infiltration of M2 macrophages.
IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy.
Lonicerin alleviates the progression of experimental rheumatoid arthritis by downregulating M1 macrophages through the NF-κB signaling pathway.
Curcumin-activated Olfactory Ensheathing Cells Improve Functional Recovery After Spinal Cord Injury by Modulating Microglia Polarization Through APOE/TREM2/NF-κB Signaling Pathway.
Smart Liposomal Nanocarrier Enhanced the Treatment of Ischemic Stroke through Neutrophil Extracellular Traps and Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase-Stimulator of Interferon Genes (cGAS-STING) Pathway Inhibition of Ischemic Penumbra.
A combination of 5/6-nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease.
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Intra-Operative Definition of Glioma Infiltrative Margins by Visualizing Immunosuppressive Tumor-Associated Macrophages.
PROMOTING MITOCHONDRIAL DYNAMIC EQUILIBRIUM ATTENUATES SEPSIS-INDUCED ACUTE LUNG INJURY BY INHIBITING PROINFLAMMATORY POLARIZATION OF ALVEOLAR MACROPHAGES.
Magnesium/gallic acid bioMOFs laden carbonized mushroom aerogel effectively heals biofilm-infected skin wounds.
Comprehensive analysis of m(6)A subtype classification for immune microenvironment of pituitary adenomas.
Systematic analysis of various RNA transcripts and construction of biological regulatory networks at the post-transcriptional level for chronic obstructive pulmonary disease.
Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface.
Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer.
TP53 mutation-related senescence is an indicator of hepatocellular carcinoma patient outcomes from multiomics profiles.
Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer.
Impact of the immune molecular profile of the tumor microenvironment on the prognosis of NSCLC.
Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.
Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization.
A fully biodegradable polydioxanone occluder for ventricle septal defect closure.
Colony-stimulating factor 1 positive (CSF1(+) ) secretory epithelial cells induce excessive trophoblast invasion in tubal pregnancy rupture.
Photo-Responsive Hydrogel for Contactless Dressing Change to Attenuate Secondary Damage and Promote Diabetic Wound Healing.
A Meaningful Attempt: Applying Dielectric Barrier Discharge Plasma to Induce Polarization of Macrophages.
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
PTN-PTPRZ1 signaling axis blocking mediates tumor microenvironment remodeling for enhanced glioblastoma treatment.
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Interleukin-32γ promotes macrophage-mediated chemoresistance by inducing CSF1-dependent M2 macrophage polarization in multiple myeloma.
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Expression of glucose transporter-1 in follicular lymphoma affected tumor-infiltrating immunocytes and was related to progression of disease within 24 months.
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
Macrophage polarization induces endothelium-to-myofibroblast transition in chronic allograft dysfunction.
Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-β-myoCAF-Dependent Mechanism.
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Loureirin B protects against cerebral ischemia/reperfusion injury through modulating M1/M2 microglial polarization via STAT6 / NF-kappaB signaling pathway.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
DIF-1 exhibits anticancer activity in breast cancer via inhibition of CXCLs/CXCR2 axis-mediated communication between cancer-associated fibroblasts and cancer cells.
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.
Pulsatilla Saponins Inhibit Experimental Lung Metastasis of Melanoma via Targeting STAT6-Mediated M2 Macrophages Polarization.
A novel immune score model predicting the prognosis and immunotherapy response of breast cancer.
Salvianolic Acid B Reduces the Inflammation of Fat Grafts by Inhibiting the NF-Kb Signalling Pathway in Macrophages.
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Deciphering the immune landscape dominated by cancer-associated fibroblasts to investigate their potential in indicating prognosis and guiding therapeutic regimens in high grade serous ovarian carcinoma.
Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes.
Murine Chronic Pancreatitis Model Induced by Partial Ligation of the Pancreatic Duct Encapsulates the Profile of Macrophage in Human Chronic Pancreatitis.
The Distributional Characteristics of M2 Macrophages in the Placental Chorionic Villi are Altered Among the Term Pregnant Women With Uncontrolled Type 2 Diabetes Mellitus.
Roles of the m(6)A Modification of RNA in the Glioblastoma Microenvironment as Revealed by Single-Cell Analyses.
Inhibition of Mer exacerbates early brain injury by regulating microglia/macrophage phenotype after subarachnoid hemorrhage in mice.
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.
Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis.
Systemic Checkpoint Blockade by PD-L1 Single-Chain Antibody Confers Potent Antitumor Immunity and Long-term Survival.
Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis.
Exendin-4 and eldecalcitol synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells through M2 macrophages polarization via PI3K/AKT pathway.
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
Ginkgolide B inactivates the NLRP3 inflammasome by promoting autophagic degradation to improve learning and memory impairment in Alzheimer's disease.
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Scorpion venom polypeptide governs alveolar macrophage M1/M2 polarization to alleviate pulmonary fibrosis.
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway.
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Resveratrol Inhibits Oxidative Stress and Regulates M1/M2-Type Polarization of Microglia via Mediation of the Nrf2/Shh Signaling Cascade after OGD/R Injury In Vitro.
nHA-loaded gelatin/alginate hydrogel with combined physical and bioactive features for maxillofacial bone repair.
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice.
Injectable hydrogel with dual-sensitive behavior for targeted delivery of oncostatin M to improve cardiac restoration after myocardial infarction.
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
LncRNA TCONS_00145741 Knockdown Prevents Thrombin-Induced M1 Differentiation of Microglia in Intracerebral Hemorrhage by Enhancing the Interaction Between DUSP6 and JNK.
TGFβ1 in Cancer-Associated Fibroblasts Is Associated With Progression and Radiosensitivity in Small-Cell Lung Cancer.
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization.
Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.
M1 Macrophage-Derived Nanovesicles Repolarize M2 Macrophages for Inhibiting the Development of Endometriosis.
Fusobacterium nucleatum Facilitates M2 Macrophage Polarization and Colorectal Carcinoma Progression by Activating TLR4/NF-κB/S100A9 Cascade.
The spatial form periosteal-bone complex promotes bone regeneration by coordinating macrophage polarization and osteogenic-angiogenic events.
Soft apoptotic-cell-inspired nanoparticles persistently bind to macrophage membranes and promote anti-inflammatory and pro-healing effects.
Regulatory role of methionine enkephalin in myeloid-derived suppressor cells and macrophages in human cutaneous squamous cell carcinoma.
XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer.
Sequential macrophage transition facilitates endogenous bone regeneration induced by Zn-doped porous microcrystalline bioactive glass.
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
Prostaglandin E(3) attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation.
Hepatoprotective effect of genistein against dimethylnitrosamine-induced liver fibrosis in rats by regulating macrophage functional properties and inhibiting the JAK2/STAT3/SOCS3 signaling pathway.
Tailoring Chemoimmunostimulant Bioscaffolds for Inhibiting Tumor Growth and Metastasis after Incomplete Microwave Ablation.
Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPARγ and RXRα.
Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Intramembranous Ossification Imitation Scaffold with the Function of Macrophage Polarization for Promoting Critical Bone Defect Repair.
Effect of CSE on M1/M2 polarization in alveolar and peritoneal macrophages at different concentrations and exposure in vitro.
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
Particulate matter exposure aggravates osteoarthritis severity.
The observed difference of RAW264.7 macrophage phenotype on mineralized collagen and hydroxyapatite.
Involvement of JNK signaling in IL4-induced M2 macrophage polarization.
Mannose-modified chitosan microspheres enhance OprF-OprI-mediated protection of mice against Pseudomonas aeruginosa infection via induction of mucosal immunity.
Qian Y, Yu H, Dong J, Liu J, Han J, Zheng T, Zhang W, Wang L, Huang Z, Wang Y
Theranostics 2026;16(5):2627-2648
Theranostics 2026;16(5):2627-2648
Kaempferol Suppresses Abdominal Aortic Aneurysm Development via Modulation of Macrophage Polarization Through the STAT/TNF Signaling Pathway.
Li M, You L, Luo S, Xu F, Li B, Deng N, Guo H, Wei Y, Zuo S, Zuo Y, Zhong L, He X, Li W, Si X
Phytotherapy research : PTR 2026 May;40(5):2948-2964
Phytotherapy research : PTR 2026 May;40(5):2948-2964
SIRT3 alleviates periodontitis inflammation by inhibiting macrophage M1 polarization regulation via FOXO3/NRF2.
Bian Y, Zhang L, Liu Y, Hou Y, Shi Y, Liu X
International immunopharmacology 2026 May 1;176:116418
International immunopharmacology 2026 May 1;176:116418
Reprogramming tumour-associated macrophages in breast cancer via si-FOXM1-loaded lipid nanoparticles enhances immune checkpoint inhibitor efficacy.
Gao Y, Li J, Xu M, Liu Y, Guo L, Li J
British journal of pharmacology 2026 Jun;183(11):3049-3073
British journal of pharmacology 2026 Jun;183(11):3049-3073
Vitamin E alleviates experimental autoimmune prostatitis by inhibiting the EGFR/MAPK pathway to reduce M1 macrophage polarization.
Zhang Y, Xu S, Zhang C, Zhao S, Dai X, Yang H, Zhang J, Zou Z, Liang C, Zhang L
International immunopharmacology 2026 Jun 1;178:116568
International immunopharmacology 2026 Jun 1;178:116568
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Xie C, Yin J, Zhu J
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Spatiotemporally Engineered Protein Delivery via Integrated Covalent Coupling and Pathological Triggers for Precision Microenvironment Reprogramming in Tissue Injury Repair.
Quan R, Hou X, Zhang J, Chen Z, Liu W, Guo B, Xu C, Yin M, Zhao S, Han S, Yin Y, Chen B, Xiao Z, Dai J, Zhao Y
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(1):e12554
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(1):e12554
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Jiang T, Zhang H, Sun Y, Ji X, Xue L, Pan C, Guo Y, Xu F
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Sanmiao pill ameliorates rheumatoid arthritis via PPARγ-mediated lipid accumulation in macrophage: A multi-omics and experimental validation.
Jiang Q, Jiang X, Xia SL, Bu Y, Wang Y, Wu H, Deng R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157697
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157697
Hydrogel with cell-cell adhesion cues enhances neural regeneration.
Tang X, Zhang S, Liu M, Liang Y, Fan Y, Sun X, He C, Yang X, Zhu R, Jin X, Zhuang Q, Ge Y, Ling J, Yang Y
Nature communications 2026 Jan 19;17(1)
Nature communications 2026 Jan 19;17(1)
Extracellular vesicle-derived miRNA-182-5p educates macrophages towards an immunosuppressive phenotype in pancreatic cancer.
Singh B, Gaur P, Bose P, Zhang Y, Li Y, Zhang Z, Kandhavelu J, Klotzbier W, Jayatilake M, Bansal S, Farhan M, Deol S, Banerjee PP, Unger K, Gupta S, Verma V, Cheema AK
Signal transduction and targeted therapy 2026 Jan 16;11(1):31
Signal transduction and targeted therapy 2026 Jan 16;11(1):31
Hofbauer Cells in Pregnancies Complicated by Gestational Diabetes Mellitus and Pathological Fetal Growth.
Fakonti G, Mappa G, Orsi N, Scott EM, Holder B, Forbes K
American journal of reproductive immunology (New York, N.Y. : 1989) 2026 Feb;95(2):e70216
American journal of reproductive immunology (New York, N.Y. : 1989) 2026 Feb;95(2):e70216
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
Fu Y, Ye C, Zhu Y, Chen T, Li Z, Chen Y
Phytotherapy research : PTR 2026 Feb;40(2):420-435
Phytotherapy research : PTR 2026 Feb;40(2):420-435
SIX2-Mediated Microglial M2 Polarization and Exosomal miR-3470b Delivery Protect Dopaminergic Neurons in Parkinson's Disease.
Kan JS, Cao XY, Ye YX, Huang XX, Sun GJ, Gao J
CNS neuroscience & therapeutics 2026 Feb;32(2):e70756
CNS neuroscience & therapeutics 2026 Feb;32(2):e70756
Icariin alleviates corneal neovascularization by regulating inflammation through inhibition of macrophage polarization and the NF-κB pathway.
Zhao L, Wei C, Guo X, Liu X, Li Y, Liu X, Li S, Li Z, Liu X, Yuan L, Gao H
Journal of translational medicine 2026 Feb 6;24(1)
Journal of translational medicine 2026 Feb 6;24(1)
DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.
Liang Y, Zeng Q, Xiao M, Li P, He R, Chen Z, Liu J, Cao J, Li J, Yin L, Zhong J, Chen X, Feng J, He J, Chen X, Zu X, Shen Y
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):985-1008
IPF AT2 cells are stuck in transition and biophysically dysfunctional.
Krivoy A, Sevilla-Sanchez D, Stancil IT, Dobrinskikh E, Kiaei SZF, Blumhagen RZ, Smith EE, Yang IV, Cool CD, Atia L, Schwartz DA
bioRxiv : the preprint server for biology 2026 Feb 17;
bioRxiv : the preprint server for biology 2026 Feb 17;
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Wang MS, Zhou HF, Li H, Gao LN, Feng Y, Zhu H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.
Chen T, Ouyang L, Mi B, Sheng Y, Al-Smadi F, Xu H, Wu Y, Zhang X, Zhou K, Wu A, Wang X, Liu G, Zhang W
Materials today. Bio 2026 Apr;37:102931
Materials today. Bio 2026 Apr;37:102931
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
Liu J, Han W, Tang J, Wan H, Wang H, Peng J, Ma W, Hu M, Hong L
Aging cell 2026 Apr;25(4):e70463
Aging cell 2026 Apr;25(4):e70463
Kif15 Orchestrates Neuronal-Microglial Communication via CX3CL1 to Impede Nerve Regeneration.
Wu R, Zhang W, Qian X, Dong Z, He X, Zhang S, Chen T, Yang L, Liu Y, Liu M
The Journal of biological chemistry 2026 Apr 27;:113090
The Journal of biological chemistry 2026 Apr 27;:113090
M2 type macrophages promote OSCC progress via conferring resistance to Erastin-induced ferroptosis.
Su C, Gu Z, Wang J, Xue Y, Song X, Yuan M, Ke H, Deng R
Scientific reports 2026 Apr 14;
Scientific reports 2026 Apr 14;
MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression.
Zhou F, Tian Y, Liao W, Ma Q, Bao H, Meng F, Jiang J
Anesthesiology research and practice 2025;2025:6624776
Anesthesiology research and practice 2025;2025:6624776
PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.
Zheng Y, Wang Y, Li J, Zheng S, Zhang L, Li Q, Ling F, Nie Q, Feng Q, Wang J, Jin C
International journal of chronic obstructive pulmonary disease 2025;20:551-564
International journal of chronic obstructive pulmonary disease 2025;20:551-564
A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression.
Zhao H, Huang L, Liu J, Feng M, Liu Y, Li H, Gong S, Chen C, Zeng S, Ren W
Frontiers in cellular neuroscience 2025;19:1553309
Frontiers in cellular neuroscience 2025;19:1553309
Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury.
Shi G, Hao X, Tu JF, Chen W, Fu Y, Ma X, Liu C, Li H
Journal of pain research 2025;18:663-671
Journal of pain research 2025;18:663-671
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
Ma G, Liu X, Jiang Q, Li S, Wu Q, Liang B, Sun F, Gu C, Liao W, Zhang Z, Shi M, Huang Q
Frontiers in immunology 2025;16:1618591
Frontiers in immunology 2025;16:1618591
FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation.
Li Z, Yin T, Guo H, Liu Z, Wang P, Liu C, Wang Q, Zhang M, Xiao Y, Wang J, Hao J, Zhang L
Frontiers in immunology 2025;16:1609989
Frontiers in immunology 2025;16:1609989
Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.
Wu Z, Luo G, Li H, Chen M, Wu G, Fan Q, Zhang C, Yu J, Lin J, Zhao J, Qi X, Huo H, Luo M, Zheng L
Frontiers in immunology 2025;16:1571007
Frontiers in immunology 2025;16:1571007
VSIG4 as a tumor-associated macrophage marker predicting adverse prognosis in diffuse large B-cell lymphoma.
Ma D, Wang Y, Shen Q, Liu X, Lu W, Li S, Yin Q, Xia L, Liu G, Chen Y, Xiang C, Liu H
Frontiers in immunology 2025;16:1567035
Frontiers in immunology 2025;16:1567035
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Guan X, Han L
Frontiers in oncology 2025;15:1590095
Frontiers in oncology 2025;15:1590095
Nao-Xin-Qing tablet inhibits macrophage inflammatory response in atherosclerosis via AMPK-α/SIRT1/PPAR-γ pathway.
Zhou G, Wang C, Lin Z, Lin L, Zhu R, Wang S, Xu J, Xie Y, Zhang Y, Cheng D, Zhou C, Lin J, Guo H, Liu M, Luo C
Journal of traditional and complementary medicine 2025 Sep;15(5):536-547
Journal of traditional and complementary medicine 2025 Sep;15(5):536-547
ANAPC5 mitigates acute lung injury through regulating macrophage M1/M2 polarization via the EGFR/CD24 axis.
Wang Y, Zhang X, Zhang J, Zhao M, Chong Y, Gu Q, Meng X, Zhao M
Cellular immunology 2025 Sep-Oct;415-416:105013
Cellular immunology 2025 Sep-Oct;415-416:105013
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Wang M, Xie Z, Tan Y, Zhou Y, Wang S, Zhang P, Li J
Human cell 2025 Sep 30;38(6):168
Human cell 2025 Sep 30;38(6):168
Moxibustion Alleviates Inflammation via SIRT5-mediated Post-translational Modification and Macrophage Polarization.
Zuo CY, Zhang CS, Zhang HX, Gou CY, Lei H, Tian FW, Wang ZX, Yin HY, Yu SG
Inflammation 2025 Oct;48(5):2908-2923
Inflammation 2025 Oct;48(5):2908-2923
Engineering a placenta-inspired biomimicking fibrous patch for chondrogenesis through immunomodulation.
Xu T, Wang P, Yu Y, Shen Y, Li D, Xiao Q, Liu M, Zhang C, Duan L, Dai W, Zhang Y, Yi B
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114120
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114120
Co-assembled polypeptides-adsorbing bridge molecules to enhance macrophage efferocytosis for the resolution of periodontitis inflammation.
Li B, Liang F, Gao Z, Zhou X, Zheng D, Zhang X, Sun M, Yan X, Li W, Wang Y, Lu X, Wu L, Sun X, Zhang H, Xu J, Wang Q
Acta biomaterialia 2025 Oct 1;205:601-615
Acta biomaterialia 2025 Oct 1;205:601-615
Slipknot-gauged mechanical transmission and robotic operation.
Xue Y, Cao J, Feng T, Zhang K, Li S, Hu J, Guo H, Zhang J, Song Y, Wang Z, Wang L, Huang Q, Zhou H, Zhou F, Shen J, Fan Y, Wang Z, Li X, Wong JW, Chen Z, Ruan D, Miao Z, Zhang B, Zhou E, Gan L, Wang X, Cao E, Chen T, Zou W, Zhang J, Lu H, Zhang Q, Liu S, Dong H, Xiong S, Peng S, Wong TW, Chen Y, Li T, Chen M, Yang X, Yang W, Cai X
Nature 2025 Nov;647(8091):889-896
Nature 2025 Nov;647(8091):889-896
Co-treatment of ticagrelor and anti-PD-1 immunotherapy in tumor-associated macrophages reduces pancreatic cancer cell growth and migration through the TGF-β1/Smad2 pathway.
Kang Y, Amoafo EB, Entsie P, Layek B, Grandgenett PM, Hollingsworth MA, di Magliano MP, Liverani E
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Nov;192:118695
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Nov;192:118695
Microneedle-facilitated Portulaca oleracea L.-derived nanovesicles ameliorate atopic dermatitis by modulating macrophage M1/M2 polarization and inhibiting NF-κB and STING signaling pathways.
Long M, Li J, Zhu Y, Ruan H, Li J, Xu F, Liu R, Yang T, Shi Y, Feng N, Zhang Y
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5966-5987
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5966-5987
A mitochondria-targeted nanomedicine for myocardial ischemia/reperfusion injury with synergistic antioxidant and anti-inflammatory properties.
Li C, Zhang Z, Luo C, Lan W, Liu C, Liu W, Xiang H, Yang J, Tang Y, Wang X
Journal of nanobiotechnology 2025 Nov 5;23(1):705
Journal of nanobiotechnology 2025 Nov 5;23(1):705
Procyanidin B2 alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the NF-κB/JAK2/STAT1 signaling pathway.
Wan H, Zhang Y, Gao Z, Shan G, Yin J, Li H
European journal of pharmacology 2025 Nov 5;1006:178149
European journal of pharmacology 2025 Nov 5;1006:178149
M2 macrophages and tumor cells engage in a metabolic feedback loop to drive HCC progression.
Nong Y, Chen X, Zhang B, Lin Z, Wuriniletu, Du C, Liu Q
Scientific reports 2025 Nov 24;15(1):41701
Scientific reports 2025 Nov 24;15(1):41701
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Gao H, Shi L, Liu J, Zhao Y, Du F, He Y, Yang X, Song N, Wen J, Zheng G
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Silk fibroin methacryloyl hydrogel loaded with silver-gallic acid nanoparticles for enhanced diabetic wound healing.
Han J, Meng Q, Xue S, Su W, Wu J
International journal of biological macromolecules 2025 May;307(Pt 4):142108
International journal of biological macromolecules 2025 May;307(Pt 4):142108
Potentilla anserina L. polysaccharide ameliorates LPS-induced acute lung injury and relevant intestinal mucosal barrier impairment.
Liu H, Wang J, Zhao J, Gu S, Chen S, Jia W, Huang S, Wu J
International journal of biological macromolecules 2025 May;305(Pt 1):140667
International journal of biological macromolecules 2025 May;305(Pt 1):140667
INHBA, transcriptionally activated by SPI1, facilitates gastric cancer progression by inducing macrophage recruitment and M2 polarization via activating the TGF-β signaling to increase CCL2.
Zhang F, Zhou C, Wang X, Liu Y, Hou Y, Niu L
Pathology, research and practice 2025 May;269:155920
Pathology, research and practice 2025 May;269:155920
M2 macrophages-derived exosomal MDH1 drives lung adenocarcinoma progression via the Hippo/YAP signaling.
Zhang J, Liu J, Liu Z, Guo L, Liu X
Pathology, research and practice 2025 May;269:155902
Pathology, research and practice 2025 May;269:155902
Anti-fibrotic, muscle-promoting antibody-drug conjugates for the improvement and treatment of DMD.
Odeh A, Sela M, Zaffryar-Eilot S, Shemesh A, Saleh MA, Mizrahi I, Coren L, Schroeder A, Hasson P
iScience 2025 May 16;28(5):112335
iScience 2025 May 16;28(5):112335
Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.
Huang S, Wang Y, Wen J, Ji W, Zeng Q, Deng K, Li M, Kuang S, Zhang W, Chan M, Zhou C, Lv Z, Huang S
Chinese medicine 2025 May 13;20(1):63
Chinese medicine 2025 May 13;20(1):63
Comprehensive analysis reveals the prognostic and immunological role of PSMD13 in hepatocellular carcinoma.
Li Y, Liu H, Liu N, Chen L, Liu R
Mammalian genome : official journal of the International Mammalian Genome Society 2025 Mar;36(1):317-330
Mammalian genome : official journal of the International Mammalian Genome Society 2025 Mar;36(1):317-330
Extracellular HSP70 facilitated β-glucan induced trained immunity in macrophages to suppress sepsis via TLR2-NF-κB axis.
Qi R, Cheng X, Chen S, Fan J
Cytokine 2025 Mar;187:156861
Cytokine 2025 Mar;187:156861
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Song X, Pan Z, Zhang Y, Yang W, Zhang T, Wang H, Chen Y, Yu X, Ding H, Li R, Ge P, Xu L, Dong G, Jiang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
Stem cell research & therapy 2025 Mar 31;16(1):161
Stem cell research & therapy 2025 Mar 31;16(1):161
Apabetalone alleviates ligature-induced periodontitis by inhibiting M1 macrophage polarization via an immunometabolic shift.
Bian T, Li H, Liu H, Guo M, Zhang Y, Hu P, Chen M
International immunopharmacology 2025 Mar 26;150:114279
International immunopharmacology 2025 Mar 26;150:114279
Estrogen via GPER downregulated HIF-1a and MIF expression, attenuated cardiac arrhythmias, and myocardial inflammation during hypobaric hypoxia.
Wowui PI, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Kanoseh AWL, Tao L, Chulu D, Yalley SK, Shaheen S, Sun H
Molecular medicine (Cambridge, Mass.) 2025 Mar 20;31(1):107
Molecular medicine (Cambridge, Mass.) 2025 Mar 20;31(1):107
Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration.
Zhao Y, An Y, Wu F, Liu L, Tay FR, Jiao Y, Wang J
Journal of nanobiotechnology 2025 Mar 11;23(1):199
Journal of nanobiotechnology 2025 Mar 11;23(1):199
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model.
Ding X, Chen C, Zhao H, Dai B, Ye L, Song T, Huang S, Wang J, You T
Neural regeneration research 2025 Mar 1;20(3):858-872
Neural regeneration research 2025 Mar 1;20(3):858-872
TREM2 promotes hippocampal neurogenesis through regulating microglial M2 polarization in APP/PS1 mice.
Peng XQ, Guo HS, Zhang X, Wu XY, Ruganzu JB, Wu SD, Zhao MT, Li L, Yang Y, Ji SF, Yang WN, Ren PY
Experimental neurology 2025 Jun;388:115205
Experimental neurology 2025 Jun;388:115205
Reducing degradation of EETs by sEH protein macromolecule depletion prevents MCAO and inhibits microglia-mediated inflammatory response.
Xu J, Guan H, Bai L, Xu Z, Du J
International journal of biological macromolecules 2025 Jun;317(Pt 1):144820
International journal of biological macromolecules 2025 Jun;317(Pt 1):144820
Reprogramming Glucose Metabolism of Macrophage for Acute Liver Failure Therapy with Itaconate Lipo-Nanodrug.
Qiu C, Zhang W, Zhao Y, Han T, Yang W, Liu Y, Jin P, Chen J, Shuai X, Ren J, Huang P
Advanced healthcare materials 2025 Jun;14(15):e2500019
Advanced healthcare materials 2025 Jun;14(15):e2500019
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
Zhang T, Meng Z, Yu H, Ding P, Kai T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Integrating multi-omics data to optimize immunotherapy in endometrial cancer: a comprehensive study.
Guan X, Cao R, Liu L, Ma L, Gao N, Yang Y, Xiao M, Du R, Su Y, Wang Z, Liu X, Han L
Discover oncology 2025 Jun 20;16(1):1161
Discover oncology 2025 Jun 20;16(1):1161
Integrative PANoptosis gene profiling reveals prognostic and therapeutic insights in prostate cancer.
Wang Y, Du Y, Wang X, Yu J, Gu Q, Yuan G, Zhu Y, Gu L, Ouyang J
Biomolecules & biomedicine 2025 Jun 19;26(7):1162-79
Biomolecules & biomedicine 2025 Jun 19;26(7):1162-79
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
The Polarization of Macrophages Regulated by KCNG3 via the Activation of ASK1 Mediated by Potassium Ion Efflux.
Zhang S, Xin Y, Yang Y, Zhang Y, Geng J
Cell biology international 2025 Jul;49(7):810-823
Cell biology international 2025 Jul;49(7):810-823
Photosensitive Biomimetic Nanomedicine-Mediated Recombination of Adipose Microenvironments for Antiobesity Therapy.
Song M, Wang L, Tian J, Qin Y, Zhang W, Chen S, Liu C
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(30):e2417377
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(30):e2417377
Coriander-Derived Exosome-Like Nanovesicles Laden Hydrogel with Antioxidant Property Accelerates Wound Healing.
Wang T, Li Y, Hao L, Liu Y, Liu D, Zhang C, Yi H, Zhang J
Macromolecular bioscience 2025 Jul;25(7):e2400640
Macromolecular bioscience 2025 Jul;25(7):e2400640
Liang-Ge-San drives macrophages toward M2 polarization for alleviating lipopolysaccharide-induced acute lung injury via activating the miR-21/PTEN axis.
Zheng Z, Yang T, Cao H, Yu J, Fang X, He X, Zou L, Tang D, Lu Z, Liu J, Yu L
Fitoterapia 2025 Jul;184:106572
Fitoterapia 2025 Jul;184:106572
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Huang J, Teng Y, Yan P, Yang Y, Lin S, Wu Q, Du Q, Li X, Yao M, Li J, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2025 Jul 16;17(14)
Cancers 2025 Jul 16;17(14)
Immunomodulatory and osteogenic effects of chitosan-based injectable hydrogel with geniposide-loaded mesoporous bioactive glass.
Deng Y, Yao H, Zhao J, Wei J
International journal of biological macromolecules 2025 Jan;284(Pt 2):138050
International journal of biological macromolecules 2025 Jan;284(Pt 2):138050
Caffeic acid-vanadium nanozymes treat skin flap ischemia-reperfusion injury through macrophage reprogramming and the upregulation of X-linked inhibitors of apoptotic proteins.
Zhao X, Shan J, Qian H, Jin X, Sun Y, Xing J, Li Q, Chen XL, Wang X
Acta pharmaceutica Sinica. B 2025 Jan;15(1):592-610
Acta pharmaceutica Sinica. B 2025 Jan;15(1):592-610
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
Zhang H, Hu J, Zhao X, Zheng B, Han Y, Luo G, Dou D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
Gastric cancer-derived exosomal let-7 g-5p mediated by SERPINE1 promotes macrophage M2 polarization and gastric cancer progression.
Ye Z, Yi J, Jiang X, Shi W, Xu H, Cao H, Qin L, Liu L, Wang T, Ma Z, Jiao Z
Journal of experimental & clinical cancer research : CR 2025 Jan 2;44(1):2
Journal of experimental & clinical cancer research : CR 2025 Jan 2;44(1):2
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Zhu J, Zhang Y, Sun Y, Yu F, Lu Y, Hu Q, Guo J, Zhang H, Chen T, Lian F, Wang J, Li X, Xiao J
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
Zhang L, Wang K, Huang L, Deng B, Chen C, Zhao K, Wang W
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Algae-inspired chitosan-pullulan-based multifunctional hydrogel for enhanced wound healing.
Liu T, Lei H, Qu L, Zhu C, Ma X, Fan D
Carbohydrate polymers 2025 Jan 1;347:122751
Carbohydrate polymers 2025 Jan 1;347:122751
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Yu Z, Wang Z, Chen Y, Wang Y, Tang L, Xi Y, Lai K, Zhang Q, Li S, Xu D, Tian A, Wu M, Wang Y, Yang G, Gao C, Huang T
Biomaterials 2025 Feb;313:122772
Biomaterials 2025 Feb;313:122772
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Sodium butyrate attenuates microglia-mediated neuroinflammation by modulating the TLR4/MyD88/NF-κB pathway and microbiome-gut-brain axis in cardiac arrest mice.
Sun J, Lu L, Lian Y, Xu S, Zhu Y, Wu Y, Lin Q, Hou J, Li Y, Yu Z
Molecular brain 2025 Feb 17;18(1):13
Molecular brain 2025 Feb 17;18(1):13
IL-27 regulates macrophage ferroptosis by inhibiting the Nrf2/HO1 signaling pathway in sepsis-induced ARDS.
Xiong M, Luo R, Zhang Z, Liu P, Peng Q, Xu F, Guo M
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 13;74(1):39
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 13;74(1):39
Catalpalactone protects rats nerve function from hypoxic lesion by polarizing microglial cells toward M2 phenotype.
Wang Y, Wang Q, Sui X, Guo M, Li L, Jia W, Tian Y, Lu Q, Wang B
European journal of medical research 2025 Feb 12;30(1):96
European journal of medical research 2025 Feb 12;30(1):96
SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma cells.
Han T, Guo X, Xie J, Tong W, Zhang L
Cancer immunology, immunotherapy : CII 2025 Feb 1;74(3):87
Cancer immunology, immunotherapy : CII 2025 Feb 1;74(3):87
PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study.
Zhao Y, Peng Y, Wang D, Zhang L, Qiu Y, Cui J, Xie F, Zhu N, Qin M, Wang Y
International endodontic journal 2025 Dec;58(12):1872-1889
International endodontic journal 2025 Dec;58(12):1872-1889
Genetic Ablation of miR-146a Induces Abdominal Aortic Aneurysm Formation by Intensifying Inflammatory M1-Like Macrophages Polarization and Vascular Smooth Muscle Cell Phenotypic Switching.
Zhong L, Sun Y, Chen G, Wang J, Yang Z, Lu W, Xiao X, Song H, Xiong J, Lin B, Wang K, Yang S, Bin J, Jiang X
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2210-2225
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2210-2225
ERO1A-positive tumor epithelial cells in colorectal cancer progression: a multi-omics perspective.
Hu S, Lou J, Chen Y, Ding M, Qin J, Nie J, Li Y, Liu Z, Xu M, Sun H, Xiao Q, Pan Y, Wang S
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3044-3068
Apoptosis : an international journal on programmed cell death 2025 Dec;30(11-12):3044-3068
Fungal β-glucan instructed miR-32-5p modulates Dectin-1 signaling mediated inflammation, reactive oxygen species and apoptosis through polarization of "M2a-like" macrophage in Candida colitis.
Yang L, Liu C, Zhu H, Wang Z, Luo Q, Huang Y, Wang H, Hu M, Shao J
Virulence 2025 Dec;16(1):2514789
Virulence 2025 Dec;16(1):2514789
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
Cheng K, Liu L, Gong M, Ji Y, Bai C, Guo X, Chen H, Pan J, Zhang Y, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
RICH1 enhances pro-inflammatory TAM infiltration in breast cancer via promoting TRIM21-mediated ubiquitination of RhoA and inhibiting STAT3 phosphorylation.
Zhou Y, Gao H, Shan L, Zhu L, Yang J, Wang B, Zhang J, Ran R, Tian Q, Liu P, Yang J
NPJ precision oncology 2025 Dec 23;10(1):49
NPJ precision oncology 2025 Dec 23;10(1):49
CCL8 suppresses ovarian cancer progression via M1 macrophage polarization and NF-κB-mediated apoptosis.
Fang J, Zhao X, Wang J, Yang Y, Xiao Y
Scientific reports 2025 Dec 17;16(1):2960
Scientific reports 2025 Dec 17;16(1):2960
Pathology-oriented multiplexing enables integrative disease mapping.
Kuehl M, Okabayashi Y, Wong MN, Gernhold L, Gut G, Kaiser N, Schwerk M, Gräfe SK, Ma FY, Tanevski J, Schäfer PSL, Mezher S, Sarabia Del Castillo J, Goldbeck-Strieder T, Zolotareva O, Hartung M, Delgado Chaves FM, Klinkert L, Gnirck AC, Spehr M, Fleck D, Joodaki M, Parra V, Shaigan M, Diebold M, Prinz M, Kranz J, Kux JM, Braun F, Kretz O, Wu H, Grahammer F, Heins S, Zimmermann M, Haas F, Kylies D, Wanner N, Czogalla J, Dumoulin B, Zolotarev N, Lindenmeyer M, Karlson P, Nyengaard JR, Sebode M, Weidemann S, Wiech T, Groene HJ, Tomas NM, Meyer-Schwesinger C, Kuppe C, Kramann R, Karras A, Bruneval P, Tharaux PL, Pastene D, Yard B, Schaub JA, McCown PJ, Pyle L, Choi YJ, Yokoo T, Baumbach J, Sáez PJ, Costa I, Turner JE, Hodgin JB, Saez-Rodriguez J, Huber TB, Bjornstad P, Kretzler M, Lenoir O, Nikolic-Paterson DJ, Pelkmans L, Bonn S, Puelles VG
Nature 2025 Aug;644(8076):516-526
Nature 2025 Aug;644(8076):516-526
Spatiotemporal Immunomodulation of Macrophages via NLRP3/IL-1β Pathway by Core-Shell Microneedles to Promote Healing of Biofilm-Infected Diabetic Ulcers.
Yang Y, Chen N, Fan J, Fan L, Cai Y, Xue L, Chen S, Yang Z, An L, Cheng J, Ren T, Li Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Aug;21(32):e2505179
Small (Weinheim an der Bergstrasse, Germany) 2025 Aug;21(32):e2505179
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair.
Li M, Hu H, Liu L, Tian M, Li X
Nanomedicine (London, England) 2025 Aug;20(15):1835-1850
Nanomedicine (London, England) 2025 Aug;20(15):1835-1850
Artemether ameliorates DSS-induced ulcerative colitis by modulating macrophage polarization.
Ren X, Li Y, Xu J, Xu Y, Huang K, Zhai B, He X
International immunopharmacology 2025 Aug 28;161:114991
International immunopharmacology 2025 Aug 28;161:114991
Efficacy of electro-acupuncture at "Weizhong" (BL40) on macrophage polarization in rats with injured lumbar multifidus.
Yuan T, He BU, Tieshan W, Dongliang Y, Wei Z, Tong L, Li Z, Zejun H
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):335-347
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):335-347
Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension.
Chen X, Li L, Deng Y, Liao J, Meng H, Liang L, Hu J, Xie D, Liang G
Immunology letters 2025 Apr;272:106974
Immunology letters 2025 Apr;272:106974
Hybrid membranes-mediated biomimetic-nanoparticle carrying miR-665 for effective tumor treatment by remodeling tumor microenvironment.
Zhang B, Zhang C, Chen C, Hong R, Shen Y, Yao C, Sun J, Zhang Y
International journal of pharmaceutics 2025 Apr 30;675:125479
International journal of pharmaceutics 2025 Apr 30;675:125479
Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages.
Jing B, Gao Y, Wang L, Guo F, Jiang D, Qin S, He M, Bai Y, An R, Xie M, Zhang L
Journal of nanobiotechnology 2025 Apr 16;23(1):296
Journal of nanobiotechnology 2025 Apr 16;23(1):296
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.
Luo C, Huang C, Zhu Y, Zhou Y, Qiao Y, Shi C, Gao Y, Guo Y, Wei L
Cell death & disease 2025 Apr 11;16(1):278
Cell death & disease 2025 Apr 11;16(1):278
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Xiao Y, He Y, Zhong D, Liu B, Tang Z, Lan X, Dong Y, Du H, Liu Y, Luo J
ACS nano 2025 Apr 1;19(12):11841-11860
ACS nano 2025 Apr 1;19(12):11841-11860
The Effect Mechanism of N6-adenosine Methylation (m6A) in Melatonin Regulated LPS-induced Colon Inflammation.
Li Y, Ma B, Wang Z, Chen Y, Dong Y
International journal of biological sciences 2024;20(7):2491-2506
International journal of biological sciences 2024;20(7):2491-2506
NLRP3 Inflammasome Inhibition After Pilocarpine-Induced Status Epilepticus Attenuates Chronic Inflammation in Epileptic Mice.
Wang L, Wang K, Chen Y, Zhang X, Xu W, Dong Z, Wang Y
Journal of inflammation research 2024;17:6143-6158
Journal of inflammation research 2024;17:6143-6158
Urine-derived stem cells genetically modified with IGF1 improve muscle regeneration.
Yi H, Chen G, Qiu S, Maxwell JT, Lin G, Criswell T, Zhang Y
American journal of clinical and experimental urology 2024;12(2):64-87
American journal of clinical and experimental urology 2024;12(2):64-87
PLA2G2D promotes immune escape in non-small cell lung cancer by regulating T cell immune function through PD-L1-expressing extracellular vesicles.
Jing H, Cao X, Li K, Liu Y, Meng M, Liu S, Ye M, Zhang J, Wu Y
Scandinavian journal of immunology 2024 Sep;100(3):e13393
Scandinavian journal of immunology 2024 Sep;100(3):e13393
Intratumoral microbiota as a novel prognostic indicator in bladder cancer.
Zhang Y, Lin H, Liang L, Jin S, Lv J, Zhou Y, Xu F, Liu F, Feng N
Scientific reports 2024 Sep 27;14(1):22198
Scientific reports 2024 Sep 27;14(1):22198
SPP1 promotes the polarization of M2 macrophages through the Jak2/Stat3 signaling pathway and accelerates the progression of idiopathic pulmonary fibrosis.
Yang X, Liu Z, Zhou J, Guo J, Han T, Liu Y, Li Y, Bai Y, Xing Y, Wu J, Hu D
International journal of molecular medicine 2024 Oct;54(4)
International journal of molecular medicine 2024 Oct;54(4)
Multifunctional Nanocomposite Hydrogel with Enhanced Chemodynamic Therapy and Starvation Therapy for Inhibiting Postoperative Tumor Recurrence.
Li Z, Ma X
International journal of molecular sciences 2024 Oct 25;25(21)
International journal of molecular sciences 2024 Oct 25;25(21)
Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation.
Chen T, Wan L, Xiao Y, Wang K, Wu P, Li C, Huang C, Liu X, Xue W, Sun G, Ji X, Lin H, Ji Z
Journal of nanobiotechnology 2024 Oct 24;22(1):653
Journal of nanobiotechnology 2024 Oct 24;22(1):653
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
Lin Y, Li L, Huang H, Wen X, Zhang Y, Zhang R, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
Distinct activation of M1 and M2 macrophages in the primary pterygium lymphangiogenesis.
Lee SJ, Koh A, Lee SH, Kim KW
Experimental eye research 2024 Nov;248:110108
Experimental eye research 2024 Nov;248:110108
A multifunctional self-reinforced injectable hydrogel for enhancing repair of infected bone defects by simultaneously targeting macrophages, bacteria, and bone marrow stromal cells.
Du J, Chu Y, Hu Y, Liu J, Liu H, Wang H, Yang C, Wang Z, Yu A, Ran J
Acta biomaterialia 2024 Nov;189:232-253
Acta biomaterialia 2024 Nov;189:232-253
Neutrophil-Driven M2-Like Macrophages Are Critical for Skin Fibrosis in a Systemic Sclerosis Model.
Gong P, Ding Y, Li W, Yang J, Su X, Tian R, Zhou Y, Wang T, Jiang J, Liu R, Fang J, Feng C, Shao C, Shi Y, Li P
The Journal of investigative dermatology 2024 Nov;144(11):2426-2439.e3
The Journal of investigative dermatology 2024 Nov;144(11):2426-2439.e3
Ultrasound Stimulation Modulates Microglia M1/M2 Polarization and Affects Hippocampal Proteomic Changes in a Mouse Model of Alzheimer's Disease.
Lu X, Sun W, Leng L, Yang Y, Gong S, Zou Q, Niu H, Wei C
Immunity, inflammation and disease 2024 Nov;12(11):e70061
Immunity, inflammation and disease 2024 Nov;12(11):e70061
Nanocomposite Hydrogel for Real-Time Wound Status Monitoring and Comprehensive Treatment.
Lei H, Yu X, Fan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2405924
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2405924
Mitochondrial transplantation following cardiopulmonary resuscitation improves neurological function in rats by inducing M2-type MG/MΦ polarization.
Zhu J, Wang Z, Xu M, Ma X, Shen M, Yan J, Zhou X
Journal of translational medicine 2024 Nov 11;22(1):1014
Journal of translational medicine 2024 Nov 11;22(1):1014
CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.
Sun H, Wang ZY, Han Y, Wei XJ, Wang YC, Yu XF
Annals of clinical and translational neurology 2024 May;11(5):1267-1279
Annals of clinical and translational neurology 2024 May;11(5):1267-1279
LncRNA CRNDE promotes hepatoma cell proliferation by regulating the metabolic reprogramming of M2 macrophages via ERK pathway.
Lin C, Jiang T, E C, Wang L, Chen T, Wang X, Xiang Y
Cancer cell international 2024 May 31;24(1):193
Cancer cell international 2024 May 31;24(1):193
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Sun Z, Xu Y, Shao B, Dang P, Hu S, Sun H, Chen C, Wang C, Liu J, Liu Y, Hu J
Journal for immunotherapy of cancer 2024 May 23;12(5)
Journal for immunotherapy of cancer 2024 May 23;12(5)
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Liang W, Liu M, Su Y, Wen Y, Wang L, Shan J, Zhao J, Xie K, Wang J
IUBMB life 2024 Mar;76(3):140-160
IUBMB life 2024 Mar;76(3):140-160
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.
Abe S, Masuda A, Matsumoto T, Inoue J, Toyama H, Sakai A, Kobayashi T, Tanaka T, Tsujimae M, Yamakawa K, Gonda M, Masuda S, Uemura H, Kohashi S, Inomata N, Nagao K, Harada Y, Miki M, Irie Y, Juri N, Ko T, Yokotani Y, Oka Y, Ota S, Kanzawa M, Itoh T, Imai T, Fukumoto T, Hara E, Kodama Y
Journal of gastroenterology 2024 Mar;59(3):250-262
Journal of gastroenterology 2024 Mar;59(3):250-262
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Nicotine regulates abnormal macrophage polarization and trophoblast invasion associated with preterm labor via the α7nAChR/SIRT1 axis.
Ye A, Li L, Chen H, Tao P, Lou S
Placenta 2024 Mar 6;147:42-51
Placenta 2024 Mar 6;147:42-51
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression.
Ma J, Tan J, Zhang W, Bai M, Liu K
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):88
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):88
23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling.
Fan Z, Cui Y, Chen L, Liu P, Duan W
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):83
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):83
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
Tang C, Jiang ST, Li CX, Jia XF, Yang WL
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.
Yang S, Du J, Wang W, Zhou D, Xi X
BMC cancer 2024 Mar 21;24(1):364
BMC cancer 2024 Mar 21;24(1):364
Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis.
Liang W, Wei R, Zhu X, Li J, Lin A, Chen J, Wu W, Jie Q
Molecular medicine (Cambridge, Mass.) 2024 Mar 16;30(1):38
Molecular medicine (Cambridge, Mass.) 2024 Mar 16;30(1):38
In Situ Reaction-Generated Aldehyde-Scavenging Polypeptides-Curcumin Conjugate Nanoassemblies for Combined Treatment of Spinal Cord Injury.
Liu Y, Lin F, Wu C, Liu W, Wang H, Xiao C, Chen X
ACS nano 2024 Mar 12;18(10):7346-7362
ACS nano 2024 Mar 12;18(10):7346-7362
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Zhang J, Jiang J, Wang B, Wang Y, Qian Y, Suo J, Li Y, Peng Z
International immunopharmacology 2024 Mar 10;129:111564
International immunopharmacology 2024 Mar 10;129:111564
Multifunctional Biodegradable Conductive Hydrogel Regulating Microenvironment for Stem Cell Therapy Enhances the Nerve Tissue Repair.
Xu C, Wu P, Yang K, Mu C, Li B, Li X, Wang Z, Liu Z, Wang X, Luo Z
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2309793
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2309793
Significance of dysregulated M2 macrophage and ESR2 in the ovarian metastasis of gastric cancer.
Gao J, Zhao Z, Pan H, Huang Y
Translational cancer research 2024 Jun 30;13(6):2674-2690
Translational cancer research 2024 Jun 30;13(6):2674-2690
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Tan N, Jian G, Peng J, Tian X, Chen B
Journal of ethnopharmacology 2024 Jun 28;328:118010
Journal of ethnopharmacology 2024 Jun 28;328:118010
COL8A1 is a potential prognostic biomarker associated with migration, proliferation, and tumor microenvironment in glioma.
Liu M, Liang W, Su Y, Wen Y, Qi J, Wang L, Su S, Zhao J, Shan J, Wang J
Experimental cell research 2024 Jun 1;439(1):114076
Experimental cell research 2024 Jun 1;439(1):114076
Nebulized platelet-derived extracellular vesicles attenuate chronic cigarette smoke-induced murine emphysema.
Xuan W, Wang S, Alarcon-Calderon A, Bagwell MS, Para R, Wang F, Zhang C, Tian X, Stalboerger P, Peterson T, Sabbah MS, Du Z, Sarrafian T, Mahlberg R, Hillestad ML, Rizzo SA, Paradise CR, Behfar A, Vassallo R
Translational research : the journal of laboratory and clinical medicine 2024 Jul;269:76-93
Translational research : the journal of laboratory and clinical medicine 2024 Jul;269:76-93
Bone marrow monocytes and macrophages from mice lacking βENaC and ASIC2 have a reduced chemotactic migration response and polarization.
Wasson R, Fleming AB, McLin J, Hildebrandt E, Drummond HA
Physiological reports 2024 Jul;12(14):e16139
Physiological reports 2024 Jul;12(14):e16139
Interaction pathways of implant metal localized corrosion and macrophage inflammatory reactions.
Li M, Wu J, Geng W, Gao P, Yang Y, Li X, Xu K, Liao Q, Cai K
Bioactive materials 2024 Jan;31:355-367
Bioactive materials 2024 Jan;31:355-367
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Zhou L, Cai E, Liu H, Cheng H, Ye X, Zhu H, Chang X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Mechanical force increases tooth movement and promotes remodeling of alveolar bone defects augmented with bovine bone mineral.
Deng J, Zhuang ZM, Xu X, Han B, Song GY, Xu TM
Progress in orthodontics 2024 Jan 8;25(1):2
Progress in orthodontics 2024 Jan 8;25(1):2
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Shuangshuang H, Mengmeng S, Lan Z, Fang Z, Yu L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway.
Deng WY, Zhou CL, Zeng MY
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117070
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117070
Mannose-Integrated Nanoparticle Hitchhike Glucose Transporter 1 Recycling to Overcome Various Barriers of Oral Delivery for Alzheimer's Disease Therapy.
Lei T, Yang Z, Jiang C, Wang X, Yang W, Yang X, Xie R, Tong F, Xia X, Huang Q, Du Y, Huang Y, Gao H
ACS nano 2024 Jan 30;18(4):3234-3250
ACS nano 2024 Jan 30;18(4):3234-3250
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
Zheng J, Chen T, Wang K, Peng C, Zhao M, Xie Q, Li B, Lin H, Zhao Z, Ji Z, Tang BZ, Liao Y
ACS nano 2024 Jan 23;18(3):2355-2369
ACS nano 2024 Jan 23;18(3):2355-2369
IL-34 attenuates acute T cell-mediated rejection following renal transplantation by upregulating M2 macrophages polarization.
Ni B, Zhang D, Zhou H, Zheng M, Wang Z, Tao J, Han Z, Ju X, Tan R, Gu M
Heliyon 2024 Jan 15;10(1):e24028
Heliyon 2024 Jan 15;10(1):e24028
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Profibrogenic macrophage-targeted delivery of mitochondrial protector via exosome formula for alleviating pulmonary fibrosis.
Zhang W, Wan Z, Qu D, Sun W, Zhang L, Liang Y, Pan L, Jiang H, Ye Z, Wei M, Yuan L, Yang G, Jin F
Bioactive materials 2024 Feb;32:488-501
Bioactive materials 2024 Feb;32:488-501
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Liu S, Liu B, Li Q, Zheng T, Liu B, Li M, Chen Z
Neural regeneration research 2024 Feb;19(2):440-446
Neural regeneration research 2024 Feb;19(2):440-446
Modulation of microglial polarization by sequential targeting surface-engineered exosomes improves therapy for ischemic stroke.
Liu X, Hao Y, Huang Z, Shi Y, Su C, Zhao L
Drug delivery and translational research 2024 Feb;14(2):418-432
Drug delivery and translational research 2024 Feb;14(2):418-432
Arginine-Nanoenzyme with Timely Angiogenesis for Promoting Diabetic Wound Healing.
Yang Y, Yang Y, Jiang J, Wu Z, Sun J, Zhi H, Chen S, Kuai L, Li B, Dong H
ACS applied materials & interfaces 2024 Feb 28;16(8):9640-9655
ACS applied materials & interfaces 2024 Feb 28;16(8):9640-9655
The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats.
Zheng W, Lu X, Chen G, Shen Y, Huang X, Peng J, Wang J, Yin Y, Song W, Xie M, Yu S, Chen L
International journal of oral science 2024 Feb 28;16(1):19
International journal of oral science 2024 Feb 28;16(1):19
Sirt3-Mediated Opa1 Deacetylation Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Alveolar Macrophage Pro-Inflammatory Polarization.
Sun M, Li Y, Xu G, Zhu J, Lu R, An S, Zeng Z, Deng Z, Cheng R, Zhang Q, Yao Y, Wu J, Zhang Y, Hu H, Chen Z, Huang Q, Wu J
Antioxidants & redox signaling 2024 Dec;41(16-18):1014-1030
Antioxidants & redox signaling 2024 Dec;41(16-18):1014-1030
Preparation of recombinant type I collagen (PF-I-80) and its functional characterization and biomedical applications in wound healing.
Zhang Y, Fu R, Zhu C, Yuwen W, Zhang J, Duan Z, Fan D
International journal of biological macromolecules 2024 Dec;282(Pt 1):136679
International journal of biological macromolecules 2024 Dec;282(Pt 1):136679
Phosphatidylserine-functional polydimethylsiloxane substrates regulate macrophage M2 polarization via modulus-dependent NF-κB/PPARγ pathway.
Zhang G, Pan R, Lai S, Liang J, Wang S, Wu S, Yu B, Zeng R
Biomaterials advances 2024 Dec;165:213997
Biomaterials advances 2024 Dec;165:213997
Swimming upregulates APOL3 through regulating macrophage polarization to inhibit glycolysis and the development of melanoma.
Lyu Z, Mahenderan A, Radhakrishnan AKGK, Chin YS, Yin C
3 Biotech 2024 Dec;14(12):307
3 Biotech 2024 Dec;14(12):307
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Biocompatible ionized air alleviates rat osteoarthritis by modulating polarization from M1 to M2 macrophages.
Yu H, Ding C, Hu Z, Liu Q, Gu X, He J, Yan Y, Yu S, Gao L, Cheng W, Wu Z, Jing J
Scientific reports 2024 Dec 30;14(1):31901
Scientific reports 2024 Dec 30;14(1):31901
NIR-II Imaging for Tracking the Spatiotemporal Immune Microenvironment in Atherosclerotic Plaques.
Shen L, Chen M, Su Y, Bi Y, Shu G, Chen W, Lu C, Zhao Z, Lv L, Zou J, Chen X, Ji J
ACS nano 2024 Dec 17;18(50):34171-34185
ACS nano 2024 Dec 17;18(50):34171-34185
Dendritic epidermal T cell hydrogel induces the polarization of M2 macrophages to promote the healing of deep tissue pressure injury.
Shan H, Wang X, Zhang J
Journal of tissue viability 2024 Aug;33(3):440-448
Journal of tissue viability 2024 Aug;33(3):440-448
Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis.
Li J, Wu J, Zhu L, Mao S, Wang S, Jia P, Dong Y
Materials today. Bio 2024 Aug;27:101130
Materials today. Bio 2024 Aug;27:101130
Melatonin regulates microglial M1/M2 polarization via AMPKα2-mediated mitophagy in attenuating sepsis-associated encephalopathy.
Yang Y, Ke J, Cao Y, Gao Y, Lin C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117092
M2 macrophage-polarized anti-inflammatory microneedle patch for accelerating biofilm-infected diabetic wound healing via modulating the insulin pathway.
Yang Y, Fan L, Jiang J, Sun J, Xue L, Ma X, Kuai L, Li B, Li Y
Journal of nanobiotechnology 2024 Aug 14;22(1):489
Journal of nanobiotechnology 2024 Aug 14;22(1):489
M2 macrophage-derived exosomes carry miR-142-3p to restore the differentiation balance of irradiated BMMSCs by targeting TGF-β1.
Huang C, Zhao L, Xiao Y, Tang Z, Jing L, Guo K, Tian L, Zong C
Molecular and cellular biochemistry 2024 Apr;479(4):993-1010
Molecular and cellular biochemistry 2024 Apr;479(4):993-1010
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case.
Zhang J, Ren Y, Liu Y, Wang Z, Li Y, Li C, Chang H, Zhang Y
Fundamental & clinical pharmacology 2024 Apr;38(2):238-251
Fundamental & clinical pharmacology 2024 Apr;38(2):238-251
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.
Clayton BLL, Kristell JD, Allan KC, Cohn EF, Karl M, Jerome AD, Garrison E, Maeno-Hikichi Y, Sturno AM, Kerr A, Shick HE, Sepeda JA, Freundt EC, Sas AR, Segal BM, Miller RH, Tesar PJ
Nature neuroscience 2024 Apr;27(4):656-665
Nature neuroscience 2024 Apr;27(4):656-665
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Ma Y, Chen H, Li H, Zheng M, Zuo X, Wang W, Wang S, Lu Y, Wang J, Li Y, Wang J, Qiu M
Cell reports. Medicine 2024 Apr 16;5(4):101488
Cell reports. Medicine 2024 Apr 16;5(4):101488
Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma.
Yan Q, Liu J, Liu Y, Wen Z, Jin D, Wang F, Gao L
Cellular and molecular life sciences : CMLS 2024 Apr 11;81(1):179
Cellular and molecular life sciences : CMLS 2024 Apr 11;81(1):179
SMPDL3B contributes to gastric adenocarcinoma cells progression by promoting the infiltration of M2 macrophages.
Su L, Hao J, Zhang N, Wu S, Wu X, Wei W
Turkish journal of medical sciences 2023;53(6):1635-1647
Turkish journal of medical sciences 2023;53(6):1635-1647
IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy.
Ye F, Wang L, Li Y, Dong C, Zhou L, Xu J
Frontiers in immunology 2023;14:1338244
Frontiers in immunology 2023;14:1338244
Lonicerin alleviates the progression of experimental rheumatoid arthritis by downregulating M1 macrophages through the NF-κB signaling pathway.
Yang X, Qian H, Meng J, Jiang H, Yuan T, Yang S, Luo Y, Bao N, Zhao J, Wang D
Phytotherapy research : PTR 2023 Sep;37(9):3939-3950
Phytotherapy research : PTR 2023 Sep;37(9):3939-3950
Curcumin-activated Olfactory Ensheathing Cells Improve Functional Recovery After Spinal Cord Injury by Modulating Microglia Polarization Through APOE/TREM2/NF-κB Signaling Pathway.
Jiang C, Chen Z, Wang X, Zhang Y, Guo X, Fan H, Huang D, He Y, Tang X, Ai Y, Liu Y, Yang H, Hao D
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Sep;18(3):476-494
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023 Sep;18(3):476-494
Smart Liposomal Nanocarrier Enhanced the Treatment of Ischemic Stroke through Neutrophil Extracellular Traps and Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase-Stimulator of Interferon Genes (cGAS-STING) Pathway Inhibition of Ischemic Penumbra.
Sun S, Lv W, Li S, Zhang Q, He W, Min Z, Teng C, Chen Y, Liu L, Yin J, Zhu B, Xu M, Dai D, Xin H
ACS nano 2023 Sep 26;17(18):17845-17857
ACS nano 2023 Sep 26;17(18):17845-17857
A combination of 5/6-nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease.
Homma K, Enoki Y, Uchida S, Taguchi K, Matsumoto K
FASEB bioAdvances 2023 Oct;5(10):377-394
FASEB bioAdvances 2023 Oct;5(10):377-394
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Jin Y, Zhang J, Xu Y, Yi K, Li F, Zhou H, Wang H, Chan HF, Lao YH, Lv S, Tao Y, Li M
Bioactive materials 2023 Oct;28:112-131
Bioactive materials 2023 Oct;28:112-131
Intra-Operative Definition of Glioma Infiltrative Margins by Visualizing Immunosuppressive Tumor-Associated Macrophages.
Cao C, Yin H, Yang B, Yue Q, Wu G, Gu M, Zhang Y, Fan Y, Dong X, Wang T, Wang C, Zhu X, Mao Y, Zhang XY, Lei Z, Li C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2304020
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2304020
PROMOTING MITOCHONDRIAL DYNAMIC EQUILIBRIUM ATTENUATES SEPSIS-INDUCED ACUTE LUNG INJURY BY INHIBITING PROINFLAMMATORY POLARIZATION OF ALVEOLAR MACROPHAGES.
Sun M, Zeng Z, Xu G, An S, Deng Z, Cheng R, Yao Y, Wu J, Hu H, Huang Q, Wu J
Shock (Augusta, Ga.) 2023 Oct 1;60(4):603-612
Shock (Augusta, Ga.) 2023 Oct 1;60(4):603-612
Magnesium/gallic acid bioMOFs laden carbonized mushroom aerogel effectively heals biofilm-infected skin wounds.
Yang G, Fan R, Yang J, Yi L, Chen S, Wan W
Biomaterials 2023 Nov;302:122347
Biomaterials 2023 Nov;302:122347
Comprehensive analysis of m(6)A subtype classification for immune microenvironment of pituitary adenomas.
Yuan F, Cai X, Wang Y, Du C, Cong Z, Zeng X, Tang C, Ma C
International immunopharmacology 2023 Nov;124(Pt A):110784
International immunopharmacology 2023 Nov;124(Pt A):110784
Systematic analysis of various RNA transcripts and construction of biological regulatory networks at the post-transcriptional level for chronic obstructive pulmonary disease.
Li B, Zhang J, Dong H, Feng X, Yu L, Zhu J, Zhang J
Journal of translational medicine 2023 Nov 7;21(1):790
Journal of translational medicine 2023 Nov 7;21(1):790
Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface.
Liu J, Deng Y, Wang A, Liu B, Zhou X, Yin T, Wang Y, Tang T, Qiu Y, Chen J, Yang J
Cell death & disease 2023 Nov 28;14(11):780
Cell death & disease 2023 Nov 28;14(11):780
Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer.
Lin X, Chen JD, Wang CY, Cai Z, Zhan R, Yang C, Zhang LY, Li LY, Xiao Y, Chen MK, Wu M
Genome biology 2023 Nov 27;24(1):268
Genome biology 2023 Nov 27;24(1):268
TP53 mutation-related senescence is an indicator of hepatocellular carcinoma patient outcomes from multiomics profiles.
Chen YY, Zhu ZY, Ma T, Zhang L, Chen J, Jiang JW, Lu CH, Ding YT, Guan WX, Yi N, Ren HZ
Smart medicine 2023 May;2(2):e20230005
Smart medicine 2023 May;2(2):e20230005
Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer.
Parker CC, Bin Salam A, Song PN, Gallegos C, Hunt A, Yates C, Jaynes J, Lopez H, Massicano AVF, Sorace AG, Fernandez S, Houson HA, Lapi SE
Molecular pharmaceutics 2023 May 1;20(5):2415-2425
Molecular pharmaceutics 2023 May 1;20(5):2415-2425
Impact of the immune molecular profile of the tumor microenvironment on the prognosis of NSCLC.
Ying H, Hang Q, Cheng G, Yang S, Lai X, Fang M
Oncology letters 2023 Mar;25(3):131
Oncology letters 2023 Mar;25(3):131
Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.
Wang W, Liu M, Shafiq M, Li H, Hashim R, El-Newehy M, El-Hamshary H, Morsi Y, Mo X
International journal of biological macromolecules 2023 Mar 31;232:123480
International journal of biological macromolecules 2023 Mar 31;232:123480
Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization.
Chen D, Hu N, Xing S, Yang L, Zhang F, Guo S, Liu S, Ma X, Liang X, Ma H
Journal of ovarian research 2023 Mar 21;16(1):58
Journal of ovarian research 2023 Mar 21;16(1):58
A fully biodegradable polydioxanone occluder for ventricle septal defect closure.
Li Z, Kong P, Liu X, Feng S, Ouyang W, Wang S, Hu X, Xie Y, Zhang F, Zhang Y, Gao R, Wang W, Pan X
Bioactive materials 2023 Jun;24:252-262
Bioactive materials 2023 Jun;24:252-262
Colony-stimulating factor 1 positive (CSF1(+) ) secretory epithelial cells induce excessive trophoblast invasion in tubal pregnancy rupture.
Zhao X, Yan L, Ji S, Zhang Y, Ha L, He C, Tian Y, Chen L, Zhu Q, Li M, Zhang J
Cell proliferation 2023 Jul;56(7):e13408
Cell proliferation 2023 Jul;56(7):e13408
Photo-Responsive Hydrogel for Contactless Dressing Change to Attenuate Secondary Damage and Promote Diabetic Wound Healing.
Li ZY, Zhang XJ, Gao YM, Song Y, Sands MX, Zhou SB, Li QF, Zhang J
Advanced healthcare materials 2023 Jul;12(17):e2202770
Advanced healthcare materials 2023 Jul;12(17):e2202770
A Meaningful Attempt: Applying Dielectric Barrier Discharge Plasma to Induce Polarization of Macrophages.
Yu H, Cheng W, Ding C, Li Z, Ouyang W, Liu Q, Wu Z, Jing J
Bioelectromagnetics 2023 Jul-Sep;44(5-6):107-118
Bioelectromagnetics 2023 Jul-Sep;44(5-6):107-118
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
Yang Y, Wang Y, Wang C, Wu S, Yao D
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
PTN-PTPRZ1 signaling axis blocking mediates tumor microenvironment remodeling for enhanced glioblastoma treatment.
Yang M, Wang B, Yin Y, Ma X, Tang L, Zhang Y, Fan Q, Yin T, Wang Y
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:63-76
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:63-76
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Sun J, Chen T, Zhao B, Fan W, Shen Y, Wei H, Zhang M, Zheng W, Peng J, Wang J, Wang Y, Fan L, Chu Y, Chen L, Yang C
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
Interleukin-32γ promotes macrophage-mediated chemoresistance by inducing CSF1-dependent M2 macrophage polarization in multiple myeloma.
Yan H, He D, Qu J, Liu Y, Xu R, Gu H, Chen J, Li Y, Zhang E, Zhao Y, He J, Cai Z
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):327-338
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):327-338
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Yan M, Jin H, Pan C, Han X
Molecular neurobiology 2023 Feb;60(2):884-900
Molecular neurobiology 2023 Feb;60(2):884-900
Expression of glucose transporter-1 in follicular lymphoma affected tumor-infiltrating immunocytes and was related to progression of disease within 24 months.
Deng Y, Ma J, Zhao S, Yang M, Sun Y, Zhang Q
Translational oncology 2023 Feb;28:101614
Translational oncology 2023 Feb;28:101614
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Li Y, Zhang J, Wang C, Jiang Z, Lai K, Wang Y, Yang G
Acta biomaterialia 2023 Feb;157:108-123
Acta biomaterialia 2023 Feb;157:108-123
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10.
Peng C, Tu G, Wang J, Wang Y, Wu P, Yu L, Li Z, Yu X
Cell death & disease 2023 Feb 24;14(2):155
Cell death & disease 2023 Feb 24;14(2):155
Macrophage polarization induces endothelium-to-myofibroblast transition in chronic allograft dysfunction.
Gui Z, Zhang X, Han Q, Hang Z, Tan R, Gu M, Wang Z
Renal failure 2023 Dec;45(1):2220418
Renal failure 2023 Dec;45(1):2220418
Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.
Zhou B, Xu Y, Xu L, Kong Y, Li K, Chen B, Li J
International journal of experimental pathology 2023 Dec;104(6):292-303
International journal of experimental pathology 2023 Dec;104(6):292-303
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-β-myoCAF-Dependent Mechanism.
Wu J, Jing X, Du Q, Sun X, Holgersson K, Gao J, He X, Hosaka K, Zhao C, Tao W, FitzGerald GA, Yang Y, Jensen LD, Cao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301505
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301505
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Wu W, Liu L, Zhu Y, Ni J, Lu J, Wang X, Ma L, Jiang Y
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Loureirin B protects against cerebral ischemia/reperfusion injury through modulating M1/M2 microglial polarization via STAT6 / NF-kappaB signaling pathway.
Li R, Jia H, Si M, Li X, Ma Z, Zhu Y, Sun W, Zhu F, Luo S
European journal of pharmacology 2023 Aug 15;953:175860
European journal of pharmacology 2023 Aug 15;953:175860
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
DIF-1 exhibits anticancer activity in breast cancer via inhibition of CXCLs/CXCR2 axis-mediated communication between cancer-associated fibroblasts and cancer cells.
Seto-Tetsuo F, Arioka M, Miura K, Inoue T, Igawa K, Tomooka K, Sasaguri T
International immunopharmacology 2023 Apr;117:109913
International immunopharmacology 2023 Apr;117:109913
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Zhang Z, Shi Y, Zhu Z, Fu J, Liu D, Liu X, Dang J, Tao H, Fan H
Cancer science 2023 Apr;114(4):1240-1255
Cancer science 2023 Apr;114(4):1240-1255
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.
Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S
Cancer discovery 2023 Apr 3;13(4):974-1001
Cancer discovery 2023 Apr 3;13(4):974-1001
Pulsatilla Saponins Inhibit Experimental Lung Metastasis of Melanoma via Targeting STAT6-Mediated M2 Macrophages Polarization.
Yang X, Wu M, Yan X, Zhang C, Luo Y, Yu J
Molecules (Basel, Switzerland) 2023 Apr 24;28(9)
Molecules (Basel, Switzerland) 2023 Apr 24;28(9)
A novel immune score model predicting the prognosis and immunotherapy response of breast cancer.
Lv W, He X, Wang Y, Zhao C, Dong M, Wu Y, Zhang Q
Scientific reports 2023 Apr 19;13(1):6403
Scientific reports 2023 Apr 19;13(1):6403
Salvianolic Acid B Reduces the Inflammation of Fat Grafts by Inhibiting the NF-Kb Signalling Pathway in Macrophages.
Sun JM, Ho CK, Gao Y, Chong CH, Liu YD, Liu YX, Zheng DN, Zhang YF, Yu L
Aesthetic surgery journal 2023 Apr 10;43(5):NP372-NP390
Aesthetic surgery journal 2023 Apr 10;43(5):NP372-NP390
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
Li X, Cui L, Feng G, Yu S, Shao G, He N, Li S
Frontiers in nutrition 2022;9:957391
Frontiers in nutrition 2022;9:957391
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Deciphering the immune landscape dominated by cancer-associated fibroblasts to investigate their potential in indicating prognosis and guiding therapeutic regimens in high grade serous ovarian carcinoma.
Li Y, Tian R, Liu J, Li J, Tan H, Wu Q, Fu X
Frontiers in immunology 2022;13:940801
Frontiers in immunology 2022;13:940801
Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes.
He Y, Zhou H, Huang X, Qu Y, Wang Y, Pei W, Zhang R, Chen S, You H
Frontiers in immunology 2022;13:909932
Frontiers in immunology 2022;13:909932
Murine Chronic Pancreatitis Model Induced by Partial Ligation of the Pancreatic Duct Encapsulates the Profile of Macrophage in Human Chronic Pancreatitis.
Peng C, Tu G, Yu L, Wu P, Zhang X, Li Z, Li Z, Yu X
Frontiers in immunology 2022;13:840887
Frontiers in immunology 2022;13:840887
The Distributional Characteristics of M2 Macrophages in the Placental Chorionic Villi are Altered Among the Term Pregnant Women With Uncontrolled Type 2 Diabetes Mellitus.
Zhang M, Cui D, Yang H
Frontiers in immunology 2022;13:837391
Frontiers in immunology 2022;13:837391
Roles of the m(6)A Modification of RNA in the Glioblastoma Microenvironment as Revealed by Single-Cell Analyses.
Yuan F, Cai X, Cong Z, Wang Y, Geng Y, Aili Y, Du C, Zhu J, Yang J, Tang C, Zhang A, Zhao S, Ma C
Frontiers in immunology 2022;13:798583
Frontiers in immunology 2022;13:798583
Inhibition of Mer exacerbates early brain injury by regulating microglia/macrophage phenotype after subarachnoid hemorrhage in mice.
Tan X, Zheng Y, Zeng H, Peng Y, Yu X, Cao S
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106659
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106659
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Lei H, Fan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.
Cai ZH, Tian YG, Li JZ, Zhao P, Li JS, Mei X, Bai YP
Bioscience reports 2022 Oct 28;42(10)
Bioscience reports 2022 Oct 28;42(10)
Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis.
He Y, Sun M, Wang J, Yang X, Lin C, Ge L, Ying C, Xu K, Liu A, Wu L
Acta biomaterialia 2022 Oct 1;151:512-527
Acta biomaterialia 2022 Oct 1;151:512-527
Systemic Checkpoint Blockade by PD-L1 Single-Chain Antibody Confers Potent Antitumor Immunity and Long-term Survival.
Wang H, Khattar V, Hensel JA, Ashton R, Lu Y, Sorace AG, Wang Y, Deshane JS, Mieher JL, Deivanayagam C, Ponnazhagan S
Molecular cancer therapeutics 2022 Nov 3;21(11):1710-1721
Molecular cancer therapeutics 2022 Nov 3;21(11):1710-1721
Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis.
Wen E, Xin G, Li S, Dong Y, Zhu Y, Wan C, Yu X, Wei Z, Wang Y, Li F, Zhang K, Niu H, Huang W
Biochemical pharmacology 2022 May;199:115030
Biochemical pharmacology 2022 May;199:115030
Exendin-4 and eldecalcitol synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells through M2 macrophages polarization via PI3K/AKT pathway.
Lu Y, Liu S, Yang P, Kou Y, Li C, Liu H, Li M
Stem cell research & therapy 2022 Mar 21;13(1):113
Stem cell research & therapy 2022 Mar 21;13(1):113
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Wang S, Yan H, Fang B, Gu C, Guo J, Qiu P, Song N, Xu W, Zhang J, Lin X, Fang X
Biomaterials 2022 Jun;285:121519
Biomaterials 2022 Jun;285:121519
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Lei X, Lin H, Wang J, Ou Z, Ruan Y, Sadagopan A, Chen W, Xie S, Chen B, Li Q, Wang J, Lin H, Zhu X, Yuan X, Tian T, Lv X, Fu S, Zhu X, Zhou J, Pan G, Xia X, Tannous BA, Ferrone S, Fan S, Li J
Nature communications 2022 Jul 6;13(1):3882
Nature communications 2022 Jul 6;13(1):3882
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
Huang X, Zha B, Zhang M, Li Y, Wu Y, Zhang R, Sheng L, Xu J, Yu Z, Gao C, Chen Z, Ding H, Ma L, Zhang Y, Zang S, Zhang TN, Liu J
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
Ginkgolide B inactivates the NLRP3 inflammasome by promoting autophagic degradation to improve learning and memory impairment in Alzheimer's disease.
Shao L, Dong C, Geng D, He Q, Shi Y
Metabolic brain disease 2022 Feb;37(2):329-341
Metabolic brain disease 2022 Feb;37(2):329-341
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, Hu X, Sun M, Ma Z, Shi Y, Liang Y, Tan Y, Zeng D, Yao F, Xu X, Yao Z, Li S, Rong X, Huang N, Sun L, Liao W, Shi M
Cancer immunology research 2022 Feb;10(2):182-199
Cancer immunology research 2022 Feb;10(2):182-199
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Liang L, Liu L, Zhou W, Yang C, Mai G, Li H, Chen Y
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Tao H, Zhao H, Ge D, Liao J, Shao L, Mo A, Hu L, Xu K, Wu J, Mu M, Li B, Tao X, Wang J
Toxicology letters 2022 Feb 1;355:150-159
Toxicology letters 2022 Feb 1;355:150-159
Scorpion venom polypeptide governs alveolar macrophage M1/M2 polarization to alleviate pulmonary fibrosis.
Xu L, Zhang Y, Dai Q, Lin N, Guan T, Song X, Hong S
Tissue & cell 2022 Dec;79:101939
Tissue & cell 2022 Dec;79:101939
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway.
Li H, Yuan Y, Chen H, Dai H, Li J
Molecular metabolism 2022 Dec;66:101617
Molecular metabolism 2022 Dec;66:101617
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Guan G, Zhang Q, Jiang Z, Liu J, Wan J, Jin P, Lv Q
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Cheng H, Guo Q, Zhao H, Liu K, Kang H, Gao F, Guo J, Yuan X, Hu S, Li F, Yang Q, Fang Z
International journal of molecular sciences 2022 Dec 26;24(1)
International journal of molecular sciences 2022 Dec 26;24(1)
Resveratrol Inhibits Oxidative Stress and Regulates M1/M2-Type Polarization of Microglia via Mediation of the Nrf2/Shh Signaling Cascade after OGD/R Injury In Vitro.
Liu J, Liao H, Chen Y, Zhu H, Li X, Liu J, Xiang Q, Zeng F, Yang Q
Journal of personalized medicine 2022 Dec 19;12(12)
Journal of personalized medicine 2022 Dec 19;12(12)
nHA-loaded gelatin/alginate hydrogel with combined physical and bioactive features for maxillofacial bone repair.
Zhou X, Sun J, Wo K, Wei H, Lei H, Zhang J, Lu X, Mei F, Tang Q, Wang Y, Luo Z, Fan L, Chu Y, Chen L
Carbohydrate polymers 2022 Dec 15;298:120127
Carbohydrate polymers 2022 Dec 15;298:120127
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice.
Fu Y, Ji W, Liu Q, Zhang L, Li C, Huan Y, Lei L, Gao X, Chen L, Feng C, Lei L, Zhai J, Li P, Cao H, Liu S, Shen Z
International journal of molecular sciences 2022 Dec 14;23(24)
International journal of molecular sciences 2022 Dec 14;23(24)
Injectable hydrogel with dual-sensitive behavior for targeted delivery of oncostatin M to improve cardiac restoration after myocardial infarction.
Jiang YL, Niu S, Lin Z, Li L, Yang P, Rao P, Yang L, Jiang L, Sun L
Journal of materials chemistry. B 2022 Aug 31;10(34):6514-6531
Journal of materials chemistry. B 2022 Aug 31;10(34):6514-6531
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Li TJ, Jin KZ, Li H, Ye LY, Li PC, Jiang B, Lin X, Liao ZY, Zhang HR, Shi SM, Lin MX, Fei QL, Xiao ZW, Xu HX, Liu L, Yu XJ, Wu WD
Cancer letters 2022 Apr 1;530:142-155
Cancer letters 2022 Apr 1;530:142-155
LncRNA TCONS_00145741 Knockdown Prevents Thrombin-Induced M1 Differentiation of Microglia in Intracerebral Hemorrhage by Enhancing the Interaction Between DUSP6 and JNK.
Wu L, Zhan Q, Liu P, Zheng H, Liu M, Min J, Xie L, Wu W
Frontiers in cell and developmental biology 2021;9:684842
Frontiers in cell and developmental biology 2021;9:684842
TGFβ1 in Cancer-Associated Fibroblasts Is Associated With Progression and Radiosensitivity in Small-Cell Lung Cancer.
Zhang J, Qi J, Wei H, Lei Y, Yu H, Liu N, Zhao L, Wang P
Frontiers in cell and developmental biology 2021;9:667645
Frontiers in cell and developmental biology 2021;9:667645
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization.
Wang Q, Zhang J, Fang S, Wang J, Han X, Liu F, Jin G
OncoTargets and therapy 2021;14:1771-1782
OncoTargets and therapy 2021;14:1771-1782
Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.
Xia Y, Zhou X, Ye Z, Yu W, Ning J, Ruan Y, Yuan R, Lin F, Ye P, Zheng D, Rao T, Cheng F
Frontiers in genetics 2021;12:774155
Frontiers in genetics 2021;12:774155
M1 Macrophage-Derived Nanovesicles Repolarize M2 Macrophages for Inhibiting the Development of Endometriosis.
Li Q, Yuan M, Jiao X, Huang Y, Li J, Li D, Ji M, Wang G
Frontiers in immunology 2021;12:707784
Frontiers in immunology 2021;12:707784
Fusobacterium nucleatum Facilitates M2 Macrophage Polarization and Colorectal Carcinoma Progression by Activating TLR4/NF-κB/S100A9 Cascade.
Hu L, Liu Y, Kong X, Wu R, Peng Q, Zhang Y, Zhou L, Duan L
Frontiers in immunology 2021;12:658681
Frontiers in immunology 2021;12:658681
The spatial form periosteal-bone complex promotes bone regeneration by coordinating macrophage polarization and osteogenic-angiogenic events.
Zhao C, Qiu P, Li M, Liang K, Tang Z, Chen P, Zhang J, Fan S, Lin X
Materials today. Bio 2021 Sep;12:100142
Materials today. Bio 2021 Sep;12:100142
Soft apoptotic-cell-inspired nanoparticles persistently bind to macrophage membranes and promote anti-inflammatory and pro-healing effects.
Zhang G, Xue H, Sun D, Yang S, Tu M, Zeng R
Acta biomaterialia 2021 Sep 1;131:452-463
Acta biomaterialia 2021 Sep 1;131:452-463
Regulatory role of methionine enkephalin in myeloid-derived suppressor cells and macrophages in human cutaneous squamous cell carcinoma.
Bai X, Shan F, Qu N, Huang H, Handley M, Griffin N, Zhang S, Cao X
International immunopharmacology 2021 Oct;99:107996
International immunopharmacology 2021 Oct;99:107996
XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer.
Zhao Y, Zhang W, Huo M, Wang P, Liu X, Wang Y, Li Y, Zhou Z, Xu N, Zhu H
Signal transduction and targeted therapy 2021 Oct 20;6(1):357
Signal transduction and targeted therapy 2021 Oct 20;6(1):357
Sequential macrophage transition facilitates endogenous bone regeneration induced by Zn-doped porous microcrystalline bioactive glass.
Bai X, Liu W, Xu L, Ye Q, Zhou H, Berg C, Yuan H, Li J, Xia W
Journal of materials chemistry. B 2021 Mar 28;9(12):2885-2898
Journal of materials chemistry. B 2021 Mar 28;9(12):2885-2898
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, Magod P, Friedmann-Morvinski D, Madi A, Satchi-Fainaro R
Nature communications 2021 Mar 26;12(1):1912
Nature communications 2021 Mar 26;12(1):1912
S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.
Wei R, Zhu WW, Yu GY, Wang X, Gao C, Zhou X, Lin ZF, Shao WQ, Wang SH, Lu M, Qin LX
International journal of cancer 2021 Mar 1;148(5):1233-1244
International journal of cancer 2021 Mar 1;148(5):1233-1244
Prostaglandin E(3) attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization.
Cui J, Shan K, Yang Q, Qi Y, Qu H, Li J, Wang R, Jia L, Chen W, Feng N, Chen YQ
Journal of cellular and molecular medicine 2021 Jun;25(12):5586-5601
Journal of cellular and molecular medicine 2021 Jun;25(12):5586-5601
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Guo S, Dong L, Li J, Chen Y, Yao Y, Zeng R, Shushakova N, Haller H, Xu G, Rong S
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation.
Yuan X, Yuan W, Ding L, Shi M, Luo L, Wan Y, Oh J, Zhou Y, Bian L, Deng DYB
Biomaterials 2021 Dec;279:121190
Biomaterials 2021 Dec;279:121190
Hepatoprotective effect of genistein against dimethylnitrosamine-induced liver fibrosis in rats by regulating macrophage functional properties and inhibiting the JAK2/STAT3/SOCS3 signaling pathway.
Xu Y, Zhang D, Yang H, Liu Y, Zhang L, Zhang C, Chen G, Hu Y, Chen J, Zhang H, Mu Y, Liu P, Liu W
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1572-1584
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1572-1584
Tailoring Chemoimmunostimulant Bioscaffolds for Inhibiting Tumor Growth and Metastasis after Incomplete Microwave Ablation.
Shen Y, Chen L, Guan X, Han X, Bo X, Li S, Sun L, Chen Y, Yue W, Xu H
ACS nano 2021 Dec 28;15(12):20414-20429
ACS nano 2021 Dec 28;15(12):20414-20429
Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPARγ and RXRα.
Feng H, Yin Y, Zheng R, Kang J
International immunopharmacology 2021 Aug;97:107809
International immunopharmacology 2021 Aug;97:107809
Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation.
Ji X, Yuan X, Ma L, Bi B, Zhu H, Lei Z, Liu W, Pu H, Jiang J, Jiang X, Zhang Y, Xiao J
Theranostics 2020;10(2):725-740
Theranostics 2020;10(2):725-740
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Cawthon CR, Kirkland RA, Pandya S, Brinson NA, de La Serre CB
Physiology & behavior 2020 Nov 1;226:113124
Physiology & behavior 2020 Nov 1;226:113124
Intramembranous Ossification Imitation Scaffold with the Function of Macrophage Polarization for Promoting Critical Bone Defect Repair.
Tang Y, Chen Y, Huang L, Gao F, Sun H, Huang C
ACS applied bio materials 2020 Jun 15;3(6):3569-3581
ACS applied bio materials 2020 Jun 15;3(6):3569-3581
Effect of CSE on M1/M2 polarization in alveolar and peritoneal macrophages at different concentrations and exposure in vitro.
Feng H, Yin Y, Ren Y, Li M, Zhang D, Xu M, Cai X, Kang J
In vitro cellular & developmental biology. Animal 2020 Feb;56(2):154-164
In vitro cellular & developmental biology. Animal 2020 Feb;56(2):154-164
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
Zhao QH, Xie F, Guo DZ, Ju FD, He J, Yao TT, Zhao PX, Pan SY, Ma XM
Brain research 2020 Dec 1;1748:147053
Brain research 2020 Dec 1;1748:147053
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
Tseng WC, Tsai MT, Chen NJ, Tarng DC
International journal of molecular sciences 2020 Aug 19;21(17)
International journal of molecular sciences 2020 Aug 19;21(17)
Particulate matter exposure aggravates osteoarthritis severity.
Peng KT, Liu JF, Chiang YC, Chen PC, Chiang MH, Shih HN, Chang PJ, Lee CW
Clinical science (London, England : 1979) 2019 Nov 15;133(21):2171-2187
Clinical science (London, England : 1979) 2019 Nov 15;133(21):2171-2187
The observed difference of RAW264.7 macrophage phenotype on mineralized collagen and hydroxyapatite.
Shi XD, Chen LW, Li SW, Sun XD, Cui FZ, Ma HM
Biomedical materials (Bristol, England) 2018 Apr 11;13(4):041001
Biomedical materials (Bristol, England) 2018 Apr 11;13(4):041001
Involvement of JNK signaling in IL4-induced M2 macrophage polarization.
Hao J, Hu Y, Li Y, Zhou Q, Lv X
Experimental cell research 2017 Aug 15;357(2):155-162
Experimental cell research 2017 Aug 15;357(2):155-162
Mannose-modified chitosan microspheres enhance OprF-OprI-mediated protection of mice against Pseudomonas aeruginosa infection via induction of mucosal immunity.
Cui Z, Han D, Sun X, Zhang M, Feng X, Sun C, Gu J, Tong C, Lei L, Han W
Applied microbiology and biotechnology 2015 Jan;99(2):667-80
Applied microbiology and biotechnology 2015 Jan;99(2):667-80
No comments: Submit comment
No validations: Submit validation data