MB0069

antibody from Bioworld Technology, Inc

Targeting: SMAD5 Dwfc, JV5-1, MADH5

Flow cytometry

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Validation data

Product number: MB0069 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Smad5 (C terminus) monoclonal antibody
Antibody type: Monoclonal
Antigen: Synthetic peptide, corresponding to the C-terminus of Human Smad5.
Description: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFÉÇ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFÉÇ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFÉÇ signaling by interfering with TGFÉÇ-mediated phosphorylation of other Smad family members.
Reactivity: Human, Mouse
Host: Mouse
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SMAD5 protein structure - MB0069 shown in red.