ABIN968229

antibody from antibodies-online

Targeting: SHC1 p66, SHC, ShcA

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN968229

Provider

antibodies-online

Product name

anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (AA 359-473) antibody

Antibody type

Monoclonal

Antigen

Human SHC

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

30

Vial size

150 µg

Concentration

250 µg/ml

Storage

Store undiluted at -20° C.

References

Submitted references

RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.

Kiely PA, Sant A, O'Connor R
The Journal of biological chemistry 2002 Jun 21;277(25):22581-9

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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling.

Ugi S, Imamura T, Ricketts W, Olefsky JM
Molecular and cellular biology 2002 Apr;22(7):2375-87

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Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor.

Imokawa G, Kobayasi T, Miyagishi M
The Journal of biological chemistry 2000 Oct 27;275(43):33321-8

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Integrin activation and focal complex formation in cardiac hypertrophy.

Laser M, Willey CD, Jiang W, Cooper G 4th, Menick DR, Zile MR, Kuppuswamy D
The Journal of biological chemistry 2000 Nov 10;275(45):35624-30

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.

Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, Nicoletti I, Grignani F, Pawson T, Pelicci PG
Cell 1992 Jul 10;70(1):93-104