PAB17283

antibody from Abnova Corporation

Targeting: RBBP8 COM1, CtIP, RIM, SCKL2

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB17283

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB17283, RRID:AB_10643883

Product name

RBBP8 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of RBBP8.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency.

Chen PL, Liu F, Cai S, Lin X, Li A, Chen Y, Gu B, Lee EY, Lee WH
Molecular and cellular biology 2005 May;25(9):3535-42

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RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.

Oswald F, Winkler M, Cao Y, Astrahantseff K, Bourteele S, Knöchel W, Borggrefe T
Molecular and cellular biology 2005 Dec;25(23):10379-90

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Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.

Li S, Chen PL, Subramanian T, Chinnadurai G, Tomlinson G, Osborne CK, Sharp ZD, Lee WH
The Journal of biological chemistry 1999 Apr 16;274(16):11334-8

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RBBP8 polyclonal antibody (Cat # PAB17283).Peptide "+" means "with peptide blocking".

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)