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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Immunohistochemistry [1]
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- Product number
- 14858-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SYK antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SYK antibody (Cat. #14858-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Neuron-Derived Sema3B Facilitates Microglial Hematoma Clearance After Intracerebral Hemorrhage.
TYROBP modulates NFκB phosphorylation and SQSTM1 expression in macrophages during Brucella Abortus LPS infection.
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing.
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Yiqi Kaimi prescription regulates protein phosphorylation to promote intestinal motility in slow transit constipation.
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
SYK Is Associated With Malignant Phenotype and Immune Checkpoints in Diffuse Glioma.
Equus β-Defensin-1 Regulates Innate IMMUNE Response in S. aureus-Infected Mouse Monocyte Macrophage.
Song J, Su G, Chen W, Xie X, Zhang Z
Frontiers in neurology 2026;17:1733679
Frontiers in neurology 2026;17:1733679
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Chen H, Xu S, Chen B, Xiong X, Hu J, Wu Y, Wang T, Wang H
Journal of diabetes investigation 2026 Mar;17(3):395-410
Journal of diabetes investigation 2026 Mar;17(3):395-410
Neuron-Derived Sema3B Facilitates Microglial Hematoma Clearance After Intracerebral Hemorrhage.
Huang B, Chen A, Zhou T, Xu Y, Sun Y, He Q
Antioxidants (Basel, Switzerland) 2026 Feb 8;15(2)
Antioxidants (Basel, Switzerland) 2026 Feb 8;15(2)
TYROBP modulates NFκB phosphorylation and SQSTM1 expression in macrophages during Brucella Abortus LPS infection.
Wu W, Chen W, Wan S, Luo X, Yang D, Wang C, Zhu H, Yu H, Li N, Hua J
Research in veterinary science 2025 Sep;193:105750
Research in veterinary science 2025 Sep;193:105750
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
Sang W, Zhang X, Hu Q, Jiang B, Guan J, Huang Z, Sun L, Sun D
Gene 2025 Sep 5;963:149572
Gene 2025 Sep 5;963:149572
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
Jiang W, Fan X, Wu H, Song J, Yang C, Zhao Z
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing.
Tong Y, Chen R, Lu X, Chen C, Sun G, Yu X, Lyu S, Feng M, Long Y, Gong L, Chen L
International journal of biological macromolecules 2025 Apr;298:139953
International journal of biological macromolecules 2025 Apr;298:139953
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Zhang J, Jiang J, Wang B, Wang Y, Qian Y, Suo J, Li Y, Peng Z
International immunopharmacology 2024 Mar 10;129:111564
International immunopharmacology 2024 Mar 10;129:111564
Yiqi Kaimi prescription regulates protein phosphorylation to promote intestinal motility in slow transit constipation.
Yao YB, Xiao CF, Wu JW, Meng LY, Liu W, Lu JG, Wang C
Journal of ethnopharmacology 2024 Jul 15;329:118118
Journal of ethnopharmacology 2024 Jul 15;329:118118
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Zhao T, Zhou Y, Zhang D, Han D, Ma J, Li S, Li T, Hu S, Li Z
Brain research 2024 Jul 1;1834:148907
Brain research 2024 Jul 1;1834:148907
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
Xu W, Song X, Qu Q, Gong Z, Xiao W
Food & function 2023 Feb 21;14(4):2059-2073
Food & function 2023 Feb 21;14(4):2059-2073
SYK Is Associated With Malignant Phenotype and Immune Checkpoints in Diffuse Glioma.
Zhou Q, Wei M, Shen W, Huang S, Fan J, Huang H
Frontiers in genetics 2022;13:899883
Frontiers in genetics 2022;13:899883
Equus β-Defensin-1 Regulates Innate IMMUNE Response in S. aureus-Infected Mouse Monocyte Macrophage.
Pei L, Liu K, Wei W, Su H, Li F, Feng Y, Wang D, Li X, Hou Y, Cao G
Animals : an open access journal from MDPI 2022 Oct 27;12(21)
Animals : an open access journal from MDPI 2022 Oct 27;12(21)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SYK antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SYK. This antibody recognizes human,mouse,rat antigen. The SYK antibody has been validated for the following applications: ELISA, IHC analysis.
