Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 644303 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#644303, RRID:AB_2565303
- Product name
- PE anti-Syk
- Antibody type
- Monoclonal
- Antigen
- Human Syk peptide aa 314-339
- Description
- Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Antibody clone number
- 4D10.2
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were surface stained with CD19 APC then treated with the Nuclear Factor Fixation and Permeabilization Buffer Set and intracellularly stained with anti-Syk (clone 4D10.2) PE (top) or mouse IgG2a, ?? PE isotype control (bottom).
- Conjugate
- Yellow dye