Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 60099 - Provider product page
- Provider
- STEMCELL Technologies Inc
- Product name
- Anti-Mouse CD24 Antibody, Clone M1/69
- Antibody type
- Monoclonal
- Description
- The M1/69 antibody reacts with murine CD24, an ~35 - 45 kDa glycoprotein expressed on lymphocytes, granulocytes, thymocytes, erythrocytes, epithelial cells, neurons, and dendritic cells. CD24 is differentially expressed during T and B cell development, and is not found on the majority of mature peripheral T cells or plasma cells. It is expressed on pro-B, pre-B and mature B cells, but expression is strongly down-regulated after B cell activation. CD24 is involved in regulating B cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells. It acts as an adhesion or co-stimulatory molecule and is involved in lymphocyte activation, proliferation and differentiation through homophilic interactions or by binding to ligands such as P-selectin (CD62P).
- Reactivity
- Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 µg
- Storage
- 2 - 8°C
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