Antibody data
- Antibody Data
- Antigen structure
- References [30]
- Comments [0]
- Validations [0]
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- Product number
- 66863-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- Phospho-Histone H3 (Ser10) antibody
- Antibody type
- Monoclonal
- Description
- Phospho-Histone H3 (Ser10) antibody (Cat. #66863-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse, pig and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C7G2
- Vial size
- 20ul, 100ul
Submitted references Decreased tRNA abundance contributes to decreased translation elongation rate in a prolonged mitosis.
Disruption of the NDC80-Nek2 axis suppresses glioblastoma stemness and enhances therapeutic efficacy.
Aptamer-functionalized exosomes combined with doxorubicin suppress GBM progression and enhance chemoradiosensitivity by promoting pyroptosis.
In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex.
Novel driver gene FIRRM regulates the cell cycle for promoting tumor growth in hepatocellular carcinoma.
Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration.
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Palmitoylated importin α regulates mitotic spindle orientation through interaction with NuMA.
SKP2 inhibition activates tumor cell-intrinsic immunity by inducing DNA replication stress and genomic instability.
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA.
Diagnostic and prognostic assessments of adrenocortical carcinomas by pathological features, immunohistochemical markers and reticular histochemistry staining.
Palmatine attenuates MYH9 mediated nuclear localization of AURKA to induce G2/M phase arrest in colorectal cancer cells.
Epigenomic landscapes during prefrontal cortex development and aging in rhesus.
Hepatocyte-derived tissue extracellular vesicles safeguard liver regeneration and support regenerative therapy.
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance.
PER2 integrates circadian disruption and pituitary tumorigenesis.
PLK1 maintains DNA methylation and cell viability by regulating phosphorylation-dependent UHRF1 protein stability.
GPR137 Inhibits Cell Proliferation and Promotes Neuronal Differentiation in the Neuro2a Cells.
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Influence of SARS-CoV-2 on Adult Human Neurogenesis.
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Oocytes could rearrange immunoglobulin production to survive over adverse environmental stimuli.
NF90-NF45 is essential for β cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway.
A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
The dynamic spatial and temporal relationships between the phalanx-forming region and the interdigits determine digit identity in the chick limb autopod.
Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer.
High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy.
Sparago E, Johnston R, Lyons SM, Blower MD
bioRxiv : the preprint server for biology 2026 Jan 14;
bioRxiv : the preprint server for biology 2026 Jan 14;
Disruption of the NDC80-Nek2 axis suppresses glioblastoma stemness and enhances therapeutic efficacy.
Niu R, Gong R, Wang W, Liu M, Xu CX, Liu HL, Lin L, Jiang T, Yin J
Journal of translational medicine 2026 Feb 9;24(1)
Journal of translational medicine 2026 Feb 9;24(1)
Aptamer-functionalized exosomes combined with doxorubicin suppress GBM progression and enhance chemoradiosensitivity by promoting pyroptosis.
Wang J, Peng L, Zhong X, Zheng S, Liang X, Du M, Xia X, Guo T, Zheng L, Fang Y, Tian Y, Shi Y, Zhang X
Materials today. Bio 2026 Apr;37:103006
Materials today. Bio 2026 Apr;37:103006
In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex.
Tokudome K, Ueki M, Homma T, Matsunaga S, Shimizu S, Ohno Y, Tomita S
British journal of pharmacology 2026 Apr 8;
British journal of pharmacology 2026 Apr 8;
Novel driver gene FIRRM regulates the cell cycle for promoting tumor growth in hepatocellular carcinoma.
Ikehara T, Otsu H, Tobo T, Hosoda K, Hirose K, Ofuchi T, Tsujimoto A, Shibuta S, Kawata K, Itoyama S, Omachi K, Takahashi Y, Motomura Y, Hiraki Y, Ando Y, Hu Q, Yonemura Y, Shimizu A, Masuda T, Soejima Y, Mimori K
Journal of gastroenterology 2026 Apr 20;
Journal of gastroenterology 2026 Apr 20;
Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration.
Xiao Y, Zhang H, Liu X, Xu P, Du H, Wang J, Shen J, Li Y, Wang Y, He C, Feng H, Liu J, Zhou Y, Liu S, Gao Z, Zang J, Bi J, Tang TS, Gu Q, Wei T, Wang J, Song M
Nature communications 2025 Mar 27;16(1):3012
Nature communications 2025 Mar 27;16(1):3012
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Cao L, Shangguan Z, Zhang Y, Luo Z, Chen C, Yan H, Fu X, Tan W, Wang C, Dou X, Zheng C, Li Q
Cellular signalling 2025 Jun;130:111675
Cellular signalling 2025 Jun;130:111675
Palmitoylated importin α regulates mitotic spindle orientation through interaction with NuMA.
Sutton PJ, Mosqueda N, Brownlee CW
EMBO reports 2025 Jul;26(13):3280-3304
EMBO reports 2025 Jul;26(13):3280-3304
SKP2 inhibition activates tumor cell-intrinsic immunity by inducing DNA replication stress and genomic instability.
Peng Y, Qi X, Ding L, Huang J, Liu Y, Zheng R, Fu Y, Yin L, Deng T, Ye Y, Chen S, Li X
British journal of cancer 2025 Jan;132(1):81-92
British journal of cancer 2025 Jan;132(1):81-92
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Zhou B, Zhao Q, Hou G, He J, Sha N, Zheng K, Peng H, Wang W, Zhou Y, Chen T, Jiang Y
Cell reports 2025 Jan 28;44(1):115116
Cell reports 2025 Jan 28;44(1):115116
Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA.
Sutton PJ, Mosqueda N, Brownlee CW
bioRxiv : the preprint server for biology 2025 Feb 6;
bioRxiv : the preprint server for biology 2025 Feb 6;
Diagnostic and prognostic assessments of adrenocortical carcinomas by pathological features, immunohistochemical markers and reticular histochemistry staining.
Gan W, Han X, Gong Y, Yang Y, Wang C, Zhang Z
Diagnostic pathology 2024 May 27;19(1):71
Diagnostic pathology 2024 May 27;19(1):71
Palmatine attenuates MYH9 mediated nuclear localization of AURKA to induce G2/M phase arrest in colorectal cancer cells.
Tang W, Li J, Zhou Y, Li J, Ma Z, Li X, Wang H, Xiong M, Chen X, Li X, Chen W, Ma H, Ye X
International immunopharmacology 2024 Dec 25;143(Pt 3):113615
International immunopharmacology 2024 Dec 25;143(Pt 3):113615
Epigenomic landscapes during prefrontal cortex development and aging in rhesus.
Ning C, Wu X, Zhao X, Lu Z, Yao X, Zhou T, Yi L, Sun Y, Wu S, Liu Z, Huang X, Gao L, Liu J
National science review 2024 Aug;11(8):nwae213
National science review 2024 Aug;11(8):nwae213
Hepatocyte-derived tissue extracellular vesicles safeguard liver regeneration and support regenerative therapy.
Ying SQ, Cao Y, Zhou ZK, Luo XY, Zhang XH, Shi K, Qiu JY, Xing SJ, Li YY, Zhang K, Jin F, Zheng CX, Jin Y, Sui BD
Journal of nanobiotechnology 2024 Aug 30;22(1):521
Journal of nanobiotechnology 2024 Aug 30;22(1):521
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance.
Cui J, Liu X, Shang Q, Sun S, Chen S, Dong J, Zhu Y, Liu L, Xia Y, Wang Y, Xiang L, Fan B, Zhan J, Zhou Y, Chen P, Zhao R, Liu X, Xing N, Wu D, Shi B, Zou Y
Molecular cancer 2024 Apr 29;23(1):86
Molecular cancer 2024 Apr 29;23(1):86
PER2 integrates circadian disruption and pituitary tumorigenesis.
Guo L, Cen H, Weng J, He Y, Guo X, He D, Liu K, Duan S, Yang J, Zhang X, Qin Z, Wan Y, Chen Z, Wu B
Theranostics 2023;13(8):2657-2672
Theranostics 2023;13(8):2657-2672
PLK1 maintains DNA methylation and cell viability by regulating phosphorylation-dependent UHRF1 protein stability.
Peng Y, Liu Y, Zheng R, Ye Y, Fu Y, Yin L, Gao Y, Fu Y, Qi X, Deng T, Zhang S, Li X
Cell death discovery 2023 Oct 3;9(1):367
Cell death discovery 2023 Oct 3;9(1):367
GPR137 Inhibits Cell Proliferation and Promotes Neuronal Differentiation in the Neuro2a Cells.
Iwasa K, Yamagishi A, Yamamoto S, Haruta C, Maruyama K, Yoshikawa K
Neurochemical research 2023 Mar;48(3):996-1008
Neurochemical research 2023 Mar;48(3):996-1008
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Li D, Liu Y, Zhan Q, Zeng Y, Peng Z, He Q, Tan Q, Cao W, Wang S, Wang J
Cells 2023 Jul 4;12(13)
Cells 2023 Jul 4;12(13)
Influence of SARS-CoV-2 on Adult Human Neurogenesis.
Stępień T, Tarka S, Chmura N, Grzegorczyk M, Acewicz A, Felczak P, Wierzba-Bobrowicz T
Cells 2023 Jan 6;12(2)
Cells 2023 Jan 6;12(2)
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Zhang C, Ma X, Wei G, Zhu X, Hu P, Chen X, Wang D, Li Y, Ruan T, Zhang W, Tao K, Wu C
iScience 2023 Jan 20;26(1):105745
iScience 2023 Jan 20;26(1):105745
Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity.
Wang W, Xiong Y, Hu X, Lu F, Qin T, Zhang L, Guo E, Yang B, Fu Y, Hu D, Fan J, Qin X, Liu C, Xiao R, Chen G, Li Z, Sun C
Acta biomaterialia 2023 Feb;157:428-441
Acta biomaterialia 2023 Feb;157:428-441
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Gao J, Wang Y, Jia Z, Xue J, Zhou T, Zu G
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Oocytes could rearrange immunoglobulin production to survive over adverse environmental stimuli.
Wang Y, Luo FQ, He YH, Yang ZX, Wang X, Li CR, Cai BQ, Chen LJ, Wang ZB, Zhang CL, Guan YC, Zhang D
Frontiers in immunology 2022;13:990077
Frontiers in immunology 2022;13:990077
NF90-NF45 is essential for β cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway.
Lai S, Higuchi T, Tsuda M, Sugiyama Y, Morisawa K, Taniguchi T, Sakamoto S
Scientific reports 2022 May 25;12(1):8837
Scientific reports 2022 May 25;12(1):8837
A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
Li YR, Liu FF, Liu WB, Zhang YF, Tian XY, Fu XJ, Xu Y, Song J, Zhang SY
Biochemical pharmacology 2022 Jul;201:115070
Biochemical pharmacology 2022 Jul;201:115070
The dynamic spatial and temporal relationships between the phalanx-forming region and the interdigits determine digit identity in the chick limb autopod.
Suzuki T, Fallon JF
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Sep;250(9):1318-1329
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Sep;250(9):1318-1329
Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer.
You J, Li J, Ke C, Xiao Y, Lu C, Huang F, Mi Y, Xia R, Li Q
Oncogene 2021 Jun;40(24):4151-4166
Oncogene 2021 Jun;40(24):4151-4166
High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy.
Edwards SJ, Carannante V, Kuhnigk K, Ring H, Tararuk T, Hallböök F, Blom H, Önfelt B, Brismar H
Frontiers in molecular biosciences 2020;7:208
Frontiers in molecular biosciences 2020;7:208
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