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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN1002944 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- ORAI1 antibody was raised in rabbits against a 16 amino acid peptide from near the carboxy terminus of human ORAI1.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- -20°C Shipping Temperature: 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Submitted references Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Soboloff J, Spassova MA, Dziadek MA, Gill DL
Biochimica et biophysica acta 2006 Nov;1763(11):1161-8
Biochimica et biophysica acta 2006 Nov;1763(11):1161-8
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A
Nature 2006 May 11;441(7090):179-85
Nature 2006 May 11;441(7090):179-85
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