Tissue expression
Cell line expression
Protein structure

PSMB3

Proteasome 20S subunit beta 3
HC10-II, MGC4147 
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]
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154 antibodies from 32 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Biorbyt
24 antibodies
Invitrogen Antibodies
9 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
46 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Novus Biologicals
7 antibodies
Everest Biotech
1 antibody
Cusabio Biotech Co., Ltd
2 antibodies
St John's Laboratory
3 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Abnova Corporation
6 antibodies
GeneTex
2 antibodies
Bethyl Laboratories
1 antibody
Acris Antibodies GmbH
5 antibodies
RabMAbs
1 antibody
Aviva Systems Biology
2 antibodies
OriGene
2 antibodies
Abgent
1 antibody
ProSci
2 antibodies
MyBioSource
3 antibodies
Creative Biolabs
4 antibodies
Boster Biological Technology
1 antibody
Enzo Life Sciences
2 antibodies
Abbexa
3 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
EMD Millipore
1 antibody
Leading Biology
3 antibodies
Creative Diagnostics
1 antibody