Antibody data
- Antibody Data
- Antigen structure
- References [80]
- Comments [0]
- Validations [0]
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- Product number
- 60287-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- CD45 antibody
- Antibody type
- Monoclonal
- Description
- CD45 antibody (Cat. #60287-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4E9B2
- Vial size
- 20ul, 150ul
Submitted references Phthalate mixtures and pregnancy loss: Linking MCNP exposure with placental dysfunction via epidemiologic and in vivo evidence.
Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation.
Chlorogenic acid targets STING to alleviate pressure overload-induced heart failure and myocardial fibrosis.
Alleviating Effects of Zophobas morio and Tenebrio molitor Larvae Protein Powder on Dextran Sodium Sulfate-Induced Inflammatory Bowel Disease in Mice.
COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.
The parkin-γ-tubulin axis regulates epidermal homeostasis and is associated with the susceptibility to psoriasis.
In vitro and in vivo characterization of oridonin analogs as anti-inflammatory agents that regulate the NF-κB and NLRP3 inflammasome axis.
Schisandrin B exacerbates acute pancreatitis by driving pathological pancreatic secretion.
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
The induction of type I interferonopathy in Trex1-P212fs mice is mediated by activation of the cGAS-STING pathway.
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis.
Cystathionine γ-lyase contributes to exacerbation of periodontal destruction in experimental periodontitis under hyperglycemia.
Bile acid receptor FXR promotes intestinal epithelial ferroptosis and subsequent ILC3 dysfunction in neonatal necrotizing enterocolitis.
Pdia3 deficiency exacerbates intestinal injury by disrupting goblet and Paneth cell function during ischemia/reperfusion.
Differentiation of lung tissue-resident c-Kit(+) cells into microvascular endothelial cells alleviates pulmonary vascular remodeling.
Omentin-1 attenuates atrial fibrillation via Src/PI3K/Akt signaling-mediated anti-fibrotic effects in cardiac fibroblasts.
Platelet Membrane-Coated HGF-PLGA Nanoparticles Promote Therapeutic Angiogenesis and Tissue Perfusion Recovery in Ischemic Hindlimbs.
E3 ubiquitin ligase ITCH-mediated proteasomal degradation of WBP2 sensitizes breast cancer cells to chemotherapy through restraining AMOTL2/c-JUN axis.
Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression.
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
Ruxolitinib attenuates bleomycin-induced pulmonary fibrosis in mice by modulating macrophage polarization through the JAK/STAT signaling pathway.
Spatial transcriptomics of gastric cancer brain metastasis reveals atypical vasculature strategies with supportive immune profiles.
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry.
An oil-in-gel type of organohydrogel loaded with methylprednisolone for the treatment of secondary injuries following spinal cord traumas.
Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury.
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
ILC2-derived CGRP triggers acute inflammation and nociceptive responses in bacterial cystitis.
Continuous Oral Administration of the Superantigen Staphylococcal Enterotoxin C2 Activates Intestinal Immunity and Modulates the Gut Microbiota in Mice.
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Antibacterial and Anti-Inflammatory Polysaccharide from Fructus Ligustri Lucidi Incorporated in PVA/Pectin Hydrogels Accelerate Wound Healing.
Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite.
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Optimization of Cell Membrane Purification for the Preparation and Characterization of Cell Membrane Liposomes.
Porcine low-density lipoprotein receptor plays an important role in classical swine fever virus infection.
DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function.
C5aR1-positive adipocytes mediate non-shivering thermogenesis in neonatal mice.
The SLE-associated TREX1-P212fs mutation disrupts ER association leading to type I interferonopathy.
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
Cell cycle associated protein 1 associates with immune infiltration and ferroptosis in gastrointestinal cancer.
Energy intake restriction significantly improves POCD after internal fixation of tibial fractures in mice.
Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis.
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
Local transplantation of mesenchymal stem cells improves encephalo-myo-synangiosis-mediated collateral neovascularization in chronic brain ischemia.
Single-cell and bulk sequencing analyses reveal the immune suppressive role of PTPN6 in glioblastoma.
Comparative Analysis of Porcine Adipose- and Wharton's Jelly-Derived Mesenchymal Stem Cells.
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
LILRB1(+) immune cell infiltration identifies immunosuppressive microenvironment and dismal outcomes of patients with ovarian cancer.
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.
Continuous oral exposure to micro- and nanoplastics induced gut microbiota dysbiosis, intestinal barrier and immune dysfunction in adult mice.
Effects of Electroacupuncture at Different Acupoints on Functional Dyspepsia Rats.
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
Tumor-Infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis.
Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease.
Immune profiling identifies CD8(+) T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer.
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Sustained release of exosomes loaded into polydopamine-modified chitin conduits promotes peripheral nerve regeneration in rats.
The immune landscape of human thymic epithelial tumors.
Protective effect of ginsenoside Rh2 against Toxoplasma gondii infection-induced neuronal injury through binding TgCDPK1 and NLRP3 to inhibit microglial NLRP3 inflammasome signaling pathway.
A Long-Term Clearing Cranial Window for Longitudinal Imaging of Cortical and Calvarial Ischemic Injury through the Intact Skull.
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Analysis of Clinical Characteristics, Radiological Predictors, Pathological Features, and Perioperative Outcomes Associated with Perinephric Fat Adhesion Degree.
Reduced expression of programmed cell death 1 and programmed cell death ligand 1 in infiltrating inflammatory cells of lichen planus without administration of immune checkpoint inhibitors.
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Hepatic progenitor cells promote the repair of schistosomiasis liver injury by inhibiting IL-33 secretion in mice.
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation.
Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.
Hydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine.
Xu N, Hu P, Shi W, Zhou Z, Zhou X, Chen S, Zhu L, Huang H, Xu C
Reproductive toxicology (Elmsford, N.Y.) 2026 May;142:109226
Reproductive toxicology (Elmsford, N.Y.) 2026 May;142:109226
Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation.
Chen KT, Huang CC, Yadav VK, Pikatan NW, Fong IH, Kuo KT, Chiu YS
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 Mar;196:119130
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 Mar;196:119130
Chlorogenic acid targets STING to alleviate pressure overload-induced heart failure and myocardial fibrosis.
Huang K, Xiao JL, Tang JY, Pu HY, Li FH, Gao K, Yu X, Guo SZ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157625
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157625
Alleviating Effects of Zophobas morio and Tenebrio molitor Larvae Protein Powder on Dextran Sodium Sulfate-Induced Inflammatory Bowel Disease in Mice.
Yang Z, Yang X, Du J, Li S, Yu J, Qiao F, Zhu F, Song B, Zhang H, Luo H, Cao Y
International journal of molecular sciences 2026 Jan 30;27(3)
International journal of molecular sciences 2026 Jan 30;27(3)
COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.
Wang Z, Shi J, Liang Y, Li D, Luo Y, Zhang Y, Chen Y, Li N, Gai X, Sun Y
Journal of nanobiotechnology 2026 Feb 6;24(1)
Journal of nanobiotechnology 2026 Feb 6;24(1)
The parkin-γ-tubulin axis regulates epidermal homeostasis and is associated with the susceptibility to psoriasis.
Liu Y, Yan S, Wang J, Dong D, Yan S, Yin H, Liu K, Liu M, Liu H, Li D, Gao J, Xie W, Zhou J
Cell death and differentiation 2026 Feb 27;
Cell death and differentiation 2026 Feb 27;
In vitro and in vivo characterization of oridonin analogs as anti-inflammatory agents that regulate the NF-κB and NLRP3 inflammasome axis.
Ou H, Wu Z, Ning J, Huang Q, Wang W, Yang G, Zhou Y, Hou A, Li P, Chen L, Jin WB
Frontiers in pharmacology 2025;16:1512740
Frontiers in pharmacology 2025;16:1512740
Schisandrin B exacerbates acute pancreatitis by driving pathological pancreatic secretion.
Ye J, Huang Y, Liu X, Lin L, Ding Y
Biochemical and biophysical research communications 2025 Sep 25;781:152520
Biochemical and biophysical research communications 2025 Sep 25;781:152520
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
Ma X, Shen M, Hu J, Zhu J, Wang Z, Zhou Q, Zeng M, Xu M, Qu Y, Zhou X
Stem cell research & therapy 2025 Oct 28;16(1):585
Stem cell research & therapy 2025 Oct 28;16(1):585
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
Yan Y, Peng J, He W, Chen Y, Ye W, Yin Z, Cao Y
Life sciences 2025 Nov 1;380:123939
Life sciences 2025 Nov 1;380:123939
The induction of type I interferonopathy in Trex1-P212fs mice is mediated by activation of the cGAS-STING pathway.
Du H, Cui D, Hu S, Zhou X, Lin X, Fu X, Feng S, Xu S, Jian W, Guo Y, Zhang S, Chen Q
International journal of biological macromolecules 2025 May;310(Pt 2):143414
International journal of biological macromolecules 2025 May;310(Pt 2):143414
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Yao X, Wang X, Zhang R, Kong L, Fan C, Qian Y
Nature communications 2025 May 5;16(1):4170
Nature communications 2025 May 5;16(1):4170
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis.
Huang X, Xie M, Wang Y, Lu X, Mei F, Zhang K, Yang X, Chen G, Yin Y, Feng G, Song W, Dong N, Deng X, Wang S, Chen L
Signal transduction and targeted therapy 2025 May 23;10(1):171
Signal transduction and targeted therapy 2025 May 23;10(1):171
Cystathionine γ-lyase contributes to exacerbation of periodontal destruction in experimental periodontitis under hyperglycemia.
Song D, He J, Cheng T, Jin L, Li S, Chen B, Li Y, Liao C
Journal of periodontology 2025 Mar;96(3):255-267
Journal of periodontology 2025 Mar;96(3):255-267
Bile acid receptor FXR promotes intestinal epithelial ferroptosis and subsequent ILC3 dysfunction in neonatal necrotizing enterocolitis.
Zhang Y, Jing Y, He J, Dong R, Li T, Li F, Zheng X, Liu G, Jia R, Xu J, Wu F, Jia C, Song J, Zhang L, Zhou P, Wang H, Yao Z, Liu Q, Yu Y, Zhou J
Immunity 2025 Mar 11;58(3):683-700.e10
Immunity 2025 Mar 11;58(3):683-700.e10
Pdia3 deficiency exacerbates intestinal injury by disrupting goblet and Paneth cell function during ischemia/reperfusion.
Zhan Y, Deng Q, Jia Y, Chen Z, Zhao X, Ling Y, Qiu Y, Wang X, Wang F, He M, Huang W, Shen J, Wen S
Cellular signalling 2025 Jun;130:111682
Cellular signalling 2025 Jun;130:111682
Differentiation of lung tissue-resident c-Kit(+) cells into microvascular endothelial cells alleviates pulmonary vascular remodeling.
Li J, Zhou Y, Shu T, Lei W, Tang Q, Yang Y, Zhang J, Chen W, Zhou B, Hu Q, Xing Y, Wang J, Wang C
Developmental cell 2025 Jun 9;60(11):1601-1617.e7
Developmental cell 2025 Jun 9;60(11):1601-1617.e7
Omentin-1 attenuates atrial fibrillation via Src/PI3K/Akt signaling-mediated anti-fibrotic effects in cardiac fibroblasts.
Li TL, Zhu NN, Zhao MX, Sun J, Yin Z, Xie P, Huang JH, Guo JP, Yuan HT, Li SX, Zhao-Liang S
European journal of pharmacology 2025 Jun 5;996:177588
European journal of pharmacology 2025 Jun 5;996:177588
Platelet Membrane-Coated HGF-PLGA Nanoparticles Promote Therapeutic Angiogenesis and Tissue Perfusion Recovery in Ischemic Hindlimbs.
Wang P, Di X, Li F, Rong Z, Lian W, Li Z, Chen T, Wang W, Zhong Q, Sun G, Ni L, Liu C
ACS applied bio materials 2025 Jan 20;8(1):399-409
ACS applied bio materials 2025 Jan 20;8(1):399-409
E3 ubiquitin ligase ITCH-mediated proteasomal degradation of WBP2 sensitizes breast cancer cells to chemotherapy through restraining AMOTL2/c-JUN axis.
Zhu M, Zhong W, Wong S, Luo X, Hong Z, Lin J, Wu J, Zhou Y, Qi Z, Chen S
Biochemical pharmacology 2025 Feb;232:116720
Biochemical pharmacology 2025 Feb;232:116720
Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression.
Huang Z, Lu C, Wang Y, Xian H, Zheng Y, Kang T, Xiang R, Xie S, Wang M, Li Z, Xia X, Yu Y, Zhang W, Zheng H, Pan R, Li D, Zhao C, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e15472
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e15472
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
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Journal of nanobiotechnology 2025 Dec 20;23(1):780
Journal of nanobiotechnology 2025 Dec 20;23(1):780
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Zhang JJ, Tian RF, Song CG, Liu R, He D, Zhang GQ, Fan XY, Duan ZC, Zhang K, Zhang TJ, Chen YT, Zhang J, Wang K, Zhao JM, Yang XM, Chen ZN, Li L
Nature communications 2025 Dec 18;17(1):399
Nature communications 2025 Dec 18;17(1):399
Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration.
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Bioactive materials 2025 Aug;50:475-493
Bioactive materials 2025 Aug;50:475-493
Ruxolitinib attenuates bleomycin-induced pulmonary fibrosis in mice by modulating macrophage polarization through the JAK/STAT signaling pathway.
Yang Z, Li Z, Liu Z, Li W, Jiao R, Liu Y, Chen R, Shi Y, Zhang T, Liu J, Meng L, Chai D, Xu Z, Li X, Zhou H, Huang H
International immunopharmacology 2025 Aug 28;161:114962
International immunopharmacology 2025 Aug 28;161:114962
Spatial transcriptomics of gastric cancer brain metastasis reveals atypical vasculature strategies with supportive immune profiles.
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Gastroenterology report 2024;12:goae067
Gastroenterology report 2024;12:goae067
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry.
Giotakis AI, Dudas J, Glueckert R, Buechel E, Riechelmann H
Histochemistry and cell biology 2024 Sep;162(3):203-214
Histochemistry and cell biology 2024 Sep;162(3):203-214
An oil-in-gel type of organohydrogel loaded with methylprednisolone for the treatment of secondary injuries following spinal cord traumas.
Tan Y, Lai T, Li Y, Tang Q, Zhang W, Liu Q, Wu S, Peng X, Sui X, Reggiori F, Jiang X, Chen Q, Wang C
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:505-524
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:505-524
Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury.
Guo Z, Yin M, Sun C, Xu G, Wang T, Jia Z, Zhang Z, Zhu C, Zheng D, Wang L, Huang S, Liu D, Zhang Y, Xie R, Gao N, Zhan L, He S, Zhu Y, Li Y, Nashan B, Andrea S, Xu J, Zhao Q, He X
EMBO molecular medicine 2024 Oct;16(10):2322-2348
EMBO molecular medicine 2024 Oct;16(10):2322-2348
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
Liu Y, Huang L, Zhang Z, Zhu Q, Xi P, Sun T, Gong B
Combinatorial chemistry & high throughput screening 2024 Oct 9;
Combinatorial chemistry & high throughput screening 2024 Oct 9;
ILC2-derived CGRP triggers acute inflammation and nociceptive responses in bacterial cystitis.
Yang Z, Liu Y, Xiang Y, Chen R, Chen L, Wang S, Lv L, Zang M, Zhou N, Li S, Shi B, Li Y
Cell reports 2024 Oct 22;43(10):114859
Cell reports 2024 Oct 22;43(10):114859
Continuous Oral Administration of the Superantigen Staphylococcal Enterotoxin C2 Activates Intestinal Immunity and Modulates the Gut Microbiota in Mice.
Gu W, Zhang H, Zhang Z, Xu M, Li X, Han Z, Fu X, Li X, Wang X, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2405039
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2405039
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Dong J, Wang B, Xiao Y, Liu J, Wang Q, Xiao H, Jin Y, Liu Z, Chen Z, Li Y, Fan S, Li Y, Cui M
Cell reports 2024 Mar 26;43(3):113846
Cell reports 2024 Mar 26;43(3):113846
Antibacterial and Anti-Inflammatory Polysaccharide from Fructus Ligustri Lucidi Incorporated in PVA/Pectin Hydrogels Accelerate Wound Healing.
Xi Y, Hu L, Chen X, Zuo L, Bai X, Du W, Xu N
Molecules (Basel, Switzerland) 2024 Mar 22;29(7)
Molecules (Basel, Switzerland) 2024 Mar 22;29(7)
Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite.
Li Y, Huang M, Wang M, Wang Y, Deng P, Li C, Huang J, Chen H, Wei Z, Ouyang Q, Zhao J, Lu Y, Su S
Cancer cell 2024 Jun 10;42(6):985-1002.e18
Cancer cell 2024 Jun 10;42(6):985-1002.e18
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Zhu C, Du Y, Huai Q, Fang N, Xu W, Yang J, Li X, Zhang Y, Zhang X, Dai H, Li X, Wang H, Dai Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Liu S, Liu B, Li Q, Zheng T, Liu B, Li M, Chen Z
Neural regeneration research 2024 Feb;19(2):440-446
Neural regeneration research 2024 Feb;19(2):440-446
Optimization of Cell Membrane Purification for the Preparation and Characterization of Cell Membrane Liposomes.
de Weerd S, Ruiter EA, Calicchia E, Portale G, Schuringa JJ, Roos WH, Salvati A
Small methods 2024 Dec;8(12):e2400498
Small methods 2024 Dec;8(12):e2400498
Porcine low-density lipoprotein receptor plays an important role in classical swine fever virus infection.
Leveringhaus E, Poljakovic R, Herrmann G, Roman-Sosa G, Becher P, Postel A
Emerging microbes & infections 2024 Dec;13(1):2327385
Emerging microbes & infections 2024 Dec;13(1):2327385
DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function.
Zhang Z, Wei H, Lin T, Zhao C, Song Y, Deng Y, Sun Y, Zhao Y, Luo Q, Zhang X, Zhang D, Li H
Poultry science 2024 Dec;103(12):104257
Poultry science 2024 Dec;103(12):104257
C5aR1-positive adipocytes mediate non-shivering thermogenesis in neonatal mice.
Wang HY, Peng XM, Yang M, Weng Y, Yang X, Zhan D, Ning Q, Luo XP, Chen Y
iScience 2024 Dec 20;27(12):111261
iScience 2024 Dec 20;27(12):111261
The SLE-associated TREX1-P212fs mutation disrupts ER association leading to type I interferonopathy.
Xu S, Xiao N, Du H, Zhou X, Huang M, Feng S, Hu S, Zhang X, Zhang S, Cui D, Zhang S, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70213
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70213
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
Yang C, Wang X, To KKW, Cui C, Luo M, Wu S, Huang L, Fu K, Pan C, Liu Z, Fan T, Yang C, Wang F, Fu L
Signal transduction and targeted therapy 2024 Apr 5;9(1):84
Signal transduction and targeted therapy 2024 Apr 5;9(1):84
Cell cycle associated protein 1 associates with immune infiltration and ferroptosis in gastrointestinal cancer.
Gao Y, Wu R, Pei Z, Ke C, Zeng D, Li X, Zhang Y
Heliyon 2024 Apr 15;10(7):e28794
Heliyon 2024 Apr 15;10(7):e28794
Energy intake restriction significantly improves POCD after internal fixation of tibial fractures in mice.
Xie W, Sun J, Zheng J, Xie W, Jiang C, Kang Z, Huang Y
American journal of translational research 2023;15(3):1667-1679
American journal of translational research 2023;15(3):1667-1679
Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis.
Liu C, Xia Y, Fu S, Meng F, Feng B, Xu L, Li L, Zuo X
Journal of innate immunity 2023;15(1):709-723
Journal of innate immunity 2023;15(1):709-723
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
Wu Q, Zou S, Liu W, Liang M, Chen Y, Chang J, Liu Y, Yu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
Local transplantation of mesenchymal stem cells improves encephalo-myo-synangiosis-mediated collateral neovascularization in chronic brain ischemia.
Zhang X, Huang Y, Liu Y, Liu Y, He X, Ma X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Stem cell research & therapy 2023 Sep 4;14(1):233
Stem cell research & therapy 2023 Sep 4;14(1):233
Single-cell and bulk sequencing analyses reveal the immune suppressive role of PTPN6 in glioblastoma.
Zhang X, Chen J, Zhang M, Liu S, Wang T, Wu T, Li B, Zhao S, Wang H, Li L, Wang C, Huang L
Aging 2023 Sep 21;15(18):9822-9841
Aging 2023 Sep 21;15(18):9822-9841
Comparative Analysis of Porcine Adipose- and Wharton's Jelly-Derived Mesenchymal Stem Cells.
Kim GY, Choi GT, Park J, Lee J, Do JT
Animals : an open access journal from MDPI 2023 Sep 17;13(18)
Animals : an open access journal from MDPI 2023 Sep 17;13(18)
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Li N, Ye Y, Wu Y, Li L, Hu J, Luo D, Li Y, Yang J, Gao Y, Hai W, Xie Y, Jiang L
iScience 2023 May 19;26(5):106571
iScience 2023 May 19;26(5):106571
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159
Regenerative therapy 2023 Mar;22:148-159
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Hao M, Fu R, Tai J, Tian Z, Yuan X, Chen Y, Wang M, Jiang H, Ji M, Lai F, Xue N, Bai L, Zhu Y, Lv X, Chen X, Jin J
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease.
Gu JJ, Hou YL, Yan YH, Li J, Wei YR, Ma K, Wang XQ, Zhang JH, Wang DD, Li CR, Li DQ, Sun LL, Gao HL
World journal of diabetes 2023 Mar 15;14(3):234-254
World journal of diabetes 2023 Mar 15;14(3):234-254
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2023 Jun;39(3):729-749
Cell biology and toxicology 2023 Jun;39(3):729-749
LILRB1(+) immune cell infiltration identifies immunosuppressive microenvironment and dismal outcomes of patients with ovarian cancer.
Xu X, Yin S, Wang Y, Zhu Q, Zheng G, Lu Y, Li T, Zhu C
International immunopharmacology 2023 Jun;119:110162
International immunopharmacology 2023 Jun;119:110162
Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.
Chen F, Cen H, Mao D, Feng R
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.
Liu X, Zhuang Y, Huang W, Wu Z, Chen Y, Shan Q, Zhang Y, Wu Z, Ding X, Qiu Z, Cui W, Wang Z
Nature communications 2023 Jul 11;14(1):4106
Nature communications 2023 Jul 11;14(1):4106
Continuous oral exposure to micro- and nanoplastics induced gut microbiota dysbiosis, intestinal barrier and immune dysfunction in adult mice.
Zhang Z, Xu M, Wang L, Gu W, Li X, Han Z, Fu X, Wang X, Li X, Su Z
Environment international 2023 Dec;182:108353
Environment international 2023 Dec;182:108353
Effects of Electroacupuncture at Different Acupoints on Functional Dyspepsia Rats.
Li YJ, Yang NN, Huang J, Lin LL, Qi LY, Ma SM, Hu CX, Wang Y, Yang JW, Liu CZ
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6548623
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6548623
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
Han B, Yang M, Liu Q, Wang G, Hou J
Disease markers 2022;2022:4782361
Disease markers 2022;2022:4782361
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
Sun Q, Tao X, Li B, Cao H, Chen H, Zou Y, Tao H, Mu M, Wang W, Xu K
Journal of inflammation research 2022;15:5827-5843
Journal of inflammation research 2022;15:5827-5843
Tumor-Infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis.
Tang D, Zhang D, Heng Y, Zhu XK, Lin HQ, Zhou J, Tao L, Lu LM
Journal of inflammation research 2022;15:1079-1097
Journal of inflammation research 2022;15:1079-1097
Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease.
Guo M, Fan S, Chen Q, Jia C, Qiu M, Bu Y, Tang WH, Zhang Y
Frontiers in immunology 2022;13:922868
Frontiers in immunology 2022;13:922868
Immune profiling identifies CD8(+) T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer.
Chen Z, Guo ML, Li YY, Yan K, Li L, Shen F, Guan H, Liu QZ, Xu B, Lian ZX
Frontiers in immunology 2022;13:894919
Frontiers in immunology 2022;13:894919
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Wang M, Liu AD, Niu Q, Feng X, Zheng YY, Chen SJ, Xu H, Li Q, Hou GQ, Bi XY, Lu YZ, Cheng PP, Liang LM, Jiang YH, Zhao LQ, Liu F, Song LJ, Zhou LL, Xiao LY, Chen F, Li SS, Ma WL, Cao X, Ye H
Theranostics 2022;12(10):4513-4535
Theranostics 2022;12(10):4513-4535
Sustained release of exosomes loaded into polydopamine-modified chitin conduits promotes peripheral nerve regeneration in rats.
Li C, Liu SY, Zhang M, Pi W, Wang B, Li QC, Lu CF, Zhang PX
Neural regeneration research 2022 Sep;17(9):2050-2057
Neural regeneration research 2022 Sep;17(9):2050-2057
The immune landscape of human thymic epithelial tumors.
Xin Z, Lin M, Hao Z, Chen D, Chen Y, Chen X, Xu X, Li J, Wu D, Chai Y, Wu P
Nature communications 2022 Sep 17;13(1):5463
Nature communications 2022 Sep 17;13(1):5463
Protective effect of ginsenoside Rh2 against Toxoplasma gondii infection-induced neuronal injury through binding TgCDPK1 and NLRP3 to inhibit microglial NLRP3 inflammasome signaling pathway.
Jin GN, Lu JM, Lan HW, Lu YN, Shen XY, Xu X, Piao LX
International immunopharmacology 2022 Nov;112:109176
International immunopharmacology 2022 Nov;112:109176
A Long-Term Clearing Cranial Window for Longitudinal Imaging of Cortical and Calvarial Ischemic Injury through the Intact Skull.
Zhang C, Liu CJ, Feng W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(17):e2105893
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jun;9(17):e2105893
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Ma Z, Li X, Mao Y, Wei C, Huang Z, Li G, Yin J, Liang X, Liu Z
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Analysis of Clinical Characteristics, Radiological Predictors, Pathological Features, and Perioperative Outcomes Associated with Perinephric Fat Adhesion Degree.
Liu J, Jiang Y, Huang H, Zhu Z, Chen J, Liu D, Wang L, Zong H, Song X, Wang X, Zhu X, Wang J, Nahayo S, Chen Q, Yang D
Journal of oncology 2021;2021:9095469
Journal of oncology 2021;2021:9095469
Reduced expression of programmed cell death 1 and programmed cell death ligand 1 in infiltrating inflammatory cells of lichen planus without administration of immune checkpoint inhibitors.
Shirouchi K, Koshikawa S, Shinya K, Watanabe H, Izumi M, Yoshimura K, Sueki H
The Journal of dermatology 2021 Sep;48(9):1428-1432
The Journal of dermatology 2021 Sep;48(9):1428-1432
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Xiong R, Jiang W, Li N, Liu B, He R, Wang B, Geng Q
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Hepatic progenitor cells promote the repair of schistosomiasis liver injury by inhibiting IL-33 secretion in mice.
Zhang B, Wu X, Li J, Ning A, Zhang B, Liu J, Song L, Yan C, Sun X, Zheng K, Wu Z
Stem cell research & therapy 2021 Oct 21;12(1):546
Stem cell research & therapy 2021 Oct 21;12(1):546
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Xi X, Zhao Y, Liu H, Li Z, Chen S, Liu D
Experimental cell research 2021 Jun 15;403(2):112598
Experimental cell research 2021 Jun 15;403(2):112598
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Liu J, Li F, Liu B, Yao Z, Li L, Liu G, Peng L, Wang Y, Huang J
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation.
Matsunari H, Watanabe M, Hasegawa K, Uchikura A, Nakano K, Umeyama K, Masaki H, Hamanaka S, Yamaguchi T, Nagaya M, Nishinakamura R, Nakauchi H, Nagashima H
Stem cell reports 2020 Jan 14;14(1):21-33
Stem cell reports 2020 Jan 14;14(1):21-33
Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.
Li Q, Zhai Y, Man X, Zhang S, An X
Cellular reprogramming 2020 Apr;22(2):82-89
Cellular reprogramming 2020 Apr;22(2):82-89
Hydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine.
Ge YS, Zhang QZ, Li H, Bai G, Jiao ZH, Wang HB
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Feb;18(1):48-61
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Feb;18(1):48-61
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