Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [4]
- Other assay [1]
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- Product number
- NBP2-47850-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Chromogranin A Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/413) - Azide and BSA Free [NBP2-47850] - Human Adrenal Gland stained with Chromogranin A Monoclonal Antibody (CGA/413)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/413) - Azide and BSA Free [NBP2-47850] - Human Pancreas stained with Chromogranin A Monoclonal Antibody (CGA/413)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/413) - Azide and BSA Free [NBP2-47850] - Human Parathyroid stained with Chromogranin A Monoclonal Antibody (CGA/413)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/413) - Azide and BSA Free [NBP2-47850] - Human Pheochromocytoma stained with Chromogranin A Monoclonal Antibody (CGA/413)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Microarray: Chromogranin A Antibody (CGA/413) - Azide and BSA Free [NBP2-47850] - alysis of Protein Array containing more than 19,000 full-length human proteins using Chromogranin A (CHGA) Mouse Monoclonal Antibody (CHGA/413). The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5.