orb106961

antibody from Biorbyt

Targeting: PARP3 ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3

Western blot (Data presented on provider website)

Antibody Data

Product number

orb106961

Provider

Biorbyt

Product name

PARP3 antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Rabbit polyclonal to PARP3. Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antibody clone number

RB42819

Vial size

80 ul