Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb106961 - Provider product page
- Provider
- Biorbyt
- Product name
- PARP3 antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Rabbit polyclonal to PARP3. Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antibody clone number
- RB42819
- Vial size
- 80 ul
- Storage
- Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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