APR02951G
antibody from Leading Biology
Targeting: PARP3
ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR02951G - Provider product page
- Provider
- Leading Biology
- Product name
- PARP3 Antibody (aa10-59)
- Antibody type
- Polyclonal
- Description
- Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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