PB9026

antibody from Boster Biological Technology

Targeting: MKI67 MIB-1, PPP1R105

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PB9026

Provider

Boster Biological Technology

Product name

Anti-Ki67/MKI67 Antibody Picoband™

Antibody type

Polyclonal

Description

Polyclonal antibody for KI67/MKI67 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB, IHC-P, ICC, IF. Reactive species: Human. KI67/MKI67 information: Molecular Weight: 358694 MW; Subcellular Localization: Nucleus . Nucleus, nucleolus . Chromosome . Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.

Reactivity

Human

Host

Rabbit

Vial size

100μg/vial

Concentration

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Handling

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

References

Submitted references

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Ling L, Wen Y, Xiong Y, Liu X, Chen J, Liu T, Zhang B
The journal of gene medicine 2024 Jan;26(1):e3571

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PAFAH1B3 is a KLF9 target gene that promotes proliferation and metastasis in pancreatic cancer.

Dong C, Yao J, Wu Z, Hu J, Sun L, Wu Z, Yan J, Yin X
Scientific reports 2024 Apr 22;14(1):9196

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Expression and Clinical Significance of Ki67 and SOX2 in Colorectal Cancer.

Hu B, Song X, Ding W, Wang H, Cai H, Huang Z
Journal of healthcare engineering 2023;2023:3783631

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miR-134-3p driven by anisomycin impairs ovarian cancer stem cell activity through inhibiting GPR137 expression.

Ling L, Wen Y, Chen H, Xiong Y, Liu X, Chen J, Liu T, Zhang B
Journal of Cancer 2023;14(18):3404-3415

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Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis.

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Nature communications 2023 Sep 18;14(1):5781

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Circ_0001955 Acts as a miR-646 Sponge to Promote the Proliferation, Metastasis and Angiogenesis of Hepatocellular Carcinoma.

Li X, Lv J, Hou L, Guo X
Digestive diseases and sciences 2022 Jun;67(6):2257-2268

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Antimicrobial peptide 17BIPHE2 inhibits the proliferation of lung cancer cells in vitro and in vivo by regulating the ERK signaling pathway.

Yang T, Li J, Jia Q, Zhan S, Zhang Q, Wang Y, Wang X
Oncology letters 2021 Jul;22(1):501

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Regulator of cullins-1 (ROC1) negatively regulates the Gli2 regulator SUFU to activate the hedgehog pathway in bladder cancer.

Wang W, Qiu J, Qu P, Chen H, Lan J, Chen H, Li L, Gu M
Cancer cell international 2021 Jan 26;21(1):75

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Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia.

Cheng R, Huang Y, Fang Y, Wang Q, Yan M, Ge Y
Pharmaceutical biology 2021 Dec;59(1):893-903

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LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.

Feng J, Ren X, Fu H, Li D, Chen X, Zu X, Liu Q, Wu M
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487

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Clinical biocharacterization of immunophenotype in hepatocellular carcinoma patients.

Pan Q, Zhou R, Su M, Wu X, Li R
International journal of clinical and experimental pathology 2017;10(7):7670-7673

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Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma.

Wang J, You H, Qi J, Yang C, Ren Y, Cheng H
Oncotarget 2017 Mar 7;8(10):17012-17026

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MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/β-catenin signaling.

Guan H, Liu C, Fang F, Huang Y, Tao T, Ling Z, You Z, Han X, Chen S, Xu B, Chen M
Oncotarget 2017 Feb 28;8(9):14693-14707

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Nek7 is overexpressed in hepatocellular carcinoma and promotes hepatocellular carcinoma cell proliferation in vitro and in vivo.

Zhou L, Wang Z, Xu X, Wan Y, Qu K, Fan H, Chen Q, Sun X, Liu C
Oncotarget 2016 Apr 5;7(14):18620-30

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MicroRNA-184 inhibits cell proliferation and invasion, and specifically targets TNFAIP2 in Glioma.

Cheng Z, Wang HZ, Li X, Wu Z, Han Y, Li Y, Chen G, Xie X, Huang Y, Du Z, Zhou Y
Journal of experimental & clinical cancer research : CR 2015 Mar 26;34(1):27

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miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells.

Li XT, Wang HZ, Wu ZW, Yang TQ, Zhao ZH, Chen GL, Xie XS, Li B, Wei YX, Huang YL, Zhou YX, Du ZW
Cellular and molecular neurobiology 2015 Jul;35(5):679-87

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Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.

Duan F, Lin M, Li C, Ding X, Qian G, Zhang H, Ge S, Fan X, Li J
Cancer biology & therapy 2014 May;15(5):544-59

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R2: identification of renal potential progenitor/stem cells that participate in the renal regeneration processes of kidney allograft fibrosis.

Bao J, Tu Z, Sun H, Luo G, Yang L, Song J, Qin M, Shi Y, Bu H, Li Y
Nephrology (Carlton, Vic.) 2008 Dec;13(6):500-7

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PlexinA1 expression in gastric carcinoma and its relationship with tumor angiogenesis and proliferation.

Zhao XY, Chen L, Li YH, Xu Q
World journal of gastroenterology 2007 Dec 28;13(48):6558-61

Immunohistochemistry

Supportive validation

Submitted by

Boster Biological Technology (provider)

Main image

Experimental details

Anti-Ki67 Picoband antibody, PB9026-1.JPGIHC(P): Human Tonsil Tissue

Additional image