Antibody data
- Antibody Data
- Antigen structure
- References [75]
- Comments [0]
- Validations
- Immunohistochemistry [32]
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- Product number
- GTX16667 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX16667, RRID:AB_422351
- Product name
- Ki67 antibody [SP6]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Rabbit
- Host
- Rabbit
Submitted references Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.
The detrimental effects of lipopolysaccharide-induced neuroinflammation on adult hippocampal neurogenesis depend on the duration of the pro-inflammatory response.
TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour.
TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells.
Endothelial repair is dependent on CD11c+ leukocytes to establish regrowing endothelial sheets with high cellular density.
Inducing a Transient Increase in Blood-Brain Barrier Permeability for Improved Liposomal Drug Therapy of Glioblastoma Multiforme.
Astrocytes migrate from human neural stem cell grafts and functionally integrate into the injured rat spinal cord.
Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies.
AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
Sexual steroid hormone receptors profiles of ovarian carcinoma in Mexican women.
A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition.
Jab1 Silencing Inhibits Proliferation and Sensitizes to Cisplatin in Biliary Tract Cancer.
Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells.
NUAK2 is a critical YAP target in liver cancer.
Treatment of intractable oral ulceration with an oral mucosa equivalent.
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.
Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis.
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway.
Long non-coding RNA H19 promotes TDRG1 expression and cisplatin resistance by sequestering miRNA-106b-5p in seminoma.
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke.
Androgen Receptor Inhibitor Enhances the Antitumor Effect of PARP Inhibitor in Breast Cancer Cells by Modulating DNA Damage Response.
Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer.
Radioprotective effect of epimedium on neurogenesis and cognition after acute radiation exposure.
Near-Infrared-Triggered Photodynamic Therapy toward Breast Cancer Cells Using Dendrimer-Functionalized Upconversion Nanoparticles.
Chitosan derived co-spheroids of neural stem cells and mesenchymal stem cells for neural regeneration.
Effects of pharmacological inhibition of plasminogen binding on liver regeneration in rats.
The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells.
Radioprotective effect of ursolic acid in radiation-induced impairment of neurogenesis, learning and memory in adolescent BALB/c mouse.
Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis.
Ramelteon, a selective MT1/MT2 receptor agonist, suppresses the proliferation and invasiveness of endometrial cancer cells.
Possible role of mitochondrial injury in Caulis Aristolochia manshuriensis-induced chronic aristolochic acid nephropathy.
Serotonin receptor 4 (5-hydroxytryptamine receptor Type 4) regulates expression of estrogen receptor beta and cell migration in hormone-naive prostate cancer.
Reprogramming-derived gene cocktail increases cardiomyocyte proliferation for heart regeneration.
Improved Proliferative Capacity of NP-Like Cells Derived from Human Mesenchymal Stromal Cells and Neuronal Transdifferentiation by Small Molecules.
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.
Age-dependent development of liver fibrosis in Glmp (gt/gt) mice.
Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2-p53 signaling.
The Role of Butylidenephthalide in Targeting the Microenvironment Which Contributes to Liver Fibrosis Amelioration.
mTOR Overactivation in Mesenchymal cells Aggravates CCl4- Induced liver Fibrosis.
ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation.
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.
Effects of Oxymatrine on the Proliferation and Apoptosis of Human Hepatoma Carcinoma Cells.
Src as a Therapeutic Target in Biliary Tract Cancer.
Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer.
TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway.
Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71.
MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1.
Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.
Filter-Dense Multicolor Microscopy.
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish.
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress.
A gp130-Src-YAP module links inflammation to epithelial regeneration.
A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis.
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model.
Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
The commonly used antimicrobial additive triclosan is a liver tumor promoter.
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.
MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11).
Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction.
Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation.
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.
Differentiation profile of peripheral blood-derived vascular progenitor cell predicts intimal hyperplasia after coronary stenting.
Suppression of autoimmune diabetes by soluble galectin-1.
Beaudry K, Langlois MJ, Montagne A, Cagnol S, Carrier JC, Rivard N
Journal of cellular physiology 2019 May;234(5):6731-6745
Journal of cellular physiology 2019 May;234(5):6731-6745
The detrimental effects of lipopolysaccharide-induced neuroinflammation on adult hippocampal neurogenesis depend on the duration of the pro-inflammatory response.
Perez-Dominguez M, Ávila-Muñoz E, Domínguez-Rivas E, Zepeda A
Neural regeneration research 2019 May;14(5):817-825
Neural regeneration research 2019 May;14(5):817-825
TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour.
Kozareva DA, Foley T, Moloney GM, Cryan JF, Nolan YM
Behavioural brain research 2019 Mar 15;360:36-50
Behavioural brain research 2019 Mar 15;360:36-50
TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells.
Li B, Wang Z, Xie JM, Wang G, Qian LQ, Guan XM, Shen XP, Qin ZH, Shen GH, Li XQ, Gao QG
Acta pharmacologica Sinica 2019 Jan;40(1):111-121
Acta pharmacologica Sinica 2019 Jan;40(1):111-121
Endothelial repair is dependent on CD11c+ leukocytes to establish regrowing endothelial sheets with high cellular density.
Yrlid U, Holm M, Levin M, Alsén S, Lindbom M, Glise L, Bergh N, Borén J, Fogelstrand P
Journal of leukocyte biology 2019 Jan;105(1):195-202
Journal of leukocyte biology 2019 Jan;105(1):195-202
Inducing a Transient Increase in Blood-Brain Barrier Permeability for Improved Liposomal Drug Therapy of Glioblastoma Multiforme.
Lundy DJ, Lee KJ, Peng IC, Hsu CH, Lin JH, Chen KH, Tien YW, Hsieh PCH
ACS nano 2019 Jan 22;13(1):97-113
ACS nano 2019 Jan 22;13(1):97-113
Astrocytes migrate from human neural stem cell grafts and functionally integrate into the injured rat spinal cord.
Lien BV, Tuszynski MH, Lu P
Experimental neurology 2019 Apr;314:46-57
Experimental neurology 2019 Apr;314:46-57
Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
Cheng YC, Tsai WC, Sung YC, Chang HH, Chen Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(2):819-831
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(2):819-831
Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies.
Eckhardt BL, Gagliardi M, Iles L, Evans K, Ivan C, Liu X, Liu CG, Souza G, Rao A, Meric-Bernstam F, Ueno NT, Bartholomeusz GA
PloS one 2018;13(5):e0195932
PloS one 2018;13(5):e0195932
AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
Fang CC, Wu CF, Liao YJ, Huang SF, Chen M, Chen YA
Scientific reports 2018 Sep 14;8(1):13802
Scientific reports 2018 Sep 14;8(1):13802
Sexual steroid hormone receptors profiles of ovarian carcinoma in Mexican women.
Gómora MJ, Morales-Vásquez F, Pedernera E, Perez-Montiel D, López-Basave H, Villa AR, Hernández-Martínez A, Mena E, Mendez C
Endocrine connections 2018 Sep 1;7(9):1006-1012
Endocrine connections 2018 Sep 1;7(9):1006-1012
A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition.
Biehs B, Dijkgraaf GJP, Piskol R, Alicke B, Boumahdi S, Peale F, Gould SE, de Sauvage FJ
Nature 2018 Oct;562(7727):429-433
Nature 2018 Oct;562(7727):429-433
Jab1 Silencing Inhibits Proliferation and Sensitizes to Cisplatin in Biliary Tract Cancer.
Nam AR, Kim JW, Park JE, Bang JH, Jin MH, Oh DY, Bang YJ
Cancer research and treatment : official journal of Korean Cancer Association 2018 Oct 1;
Cancer research and treatment : official journal of Korean Cancer Association 2018 Oct 1;
Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells.
Lin JH, Tu SH, Chen LC, Huang CC, Chang HL, Cheng TC, Chang HW, Wu CH, Wu HC, Ho YS
Breast cancer research and treatment 2018 Nov;172(1):45-59
Breast cancer research and treatment 2018 Nov;172(1):45-59
NUAK2 is a critical YAP target in liver cancer.
Yuan WC, Pepe-Mooney B, Galli GG, Dill MT, Huang HT, Hao M, Wang Y, Liang H, Calogero RA, Camargo FD
Nature communications 2018 Nov 16;9(1):4834
Nature communications 2018 Nov 16;9(1):4834
Treatment of intractable oral ulceration with an oral mucosa equivalent.
Lee J, Shin D, Roh JL
Journal of biomedical materials research. Part B, Applied biomaterials 2018 Nov 12;
Journal of biomedical materials research. Part B, Applied biomaterials 2018 Nov 12;
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.
Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K
Nature communications 2018 May 23;9(1):2028
Nature communications 2018 May 23;9(1):2028
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.
Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, Jaeger S, Schlesner M, Aloy P, Eils R, Plass C, Augustin HG
eLife 2018 May 11;7
eLife 2018 May 11;7
Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis.
Cheng ZF, Pai RK, Cartwright CA
American journal of physiology. Gastrointestinal and liver physiology 2018 Jan 1;314(1):G1-G13
American journal of physiology. Gastrointestinal and liver physiology 2018 Jan 1;314(1):G1-G13
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Qian L, Li X, Ye P, Wang G, Dai W, Liu Y, Gao Q, Shen G
Cytotechnology 2018 Feb;70(1):83-94
Cytotechnology 2018 Feb;70(1):83-94
Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway.
Bi T, Zhu A, Yang X, Qiao H, Tang J, Liu Y, Lv R
Cytotechnology 2018 Feb;70(1):439-448
Cytotechnology 2018 Feb;70(1):439-448
Long non-coding RNA H19 promotes TDRG1 expression and cisplatin resistance by sequestering miRNA-106b-5p in seminoma.
Wei J, Gan Y, Peng D, Jiang X, Kitazawa R, Xiang Y, Dai Y, Tang Y, Yang J
Cancer medicine 2018 Dec;7(12):6247-6257
Cancer medicine 2018 Dec;7(12):6247-6257
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke.
Wu CC, Wang LC, Su YT, Wei WY, Tsai KJ
Biomaterials 2018 Dec;185:142-154
Biomaterials 2018 Dec;185:142-154
Androgen Receptor Inhibitor Enhances the Antitumor Effect of PARP Inhibitor in Breast Cancer Cells by Modulating DNA Damage Response.
Min A, Jang H, Kim S, Lee KH, Kim DK, Suh KJ, Yang Y, Elvin P, O'Connor MJ, Im SA
Molecular cancer therapeutics 2018 Dec;17(12):2507-2518
Molecular cancer therapeutics 2018 Dec;17(12):2507-2518
Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer.
Nam AR, Jin MH, Park JE, Bang JH, Oh DY, Bang YJ
Cancer research and treatment : official journal of Korean Cancer Association 2018 Dec 3;
Cancer research and treatment : official journal of Korean Cancer Association 2018 Dec 3;
Radioprotective effect of epimedium on neurogenesis and cognition after acute radiation exposure.
Wang SW, Ren BX, Qian F, Luo XZ, Tang X, Peng XC, Huang JR, Tang FR
Neuroscience research 2018 Aug 23;
Neuroscience research 2018 Aug 23;
Near-Infrared-Triggered Photodynamic Therapy toward Breast Cancer Cells Using Dendrimer-Functionalized Upconversion Nanoparticles.
Wang BY, Liao ML, Hong GC, Chang WW, Chu CC
Nanomaterials (Basel, Switzerland) 2017 Sep 11;7(9)
Nanomaterials (Basel, Switzerland) 2017 Sep 11;7(9)
Chitosan derived co-spheroids of neural stem cells and mesenchymal stem cells for neural regeneration.
Han HW, Hsu SH
Colloids and surfaces. B, Biointerfaces 2017 Oct 1;158:527-538
Colloids and surfaces. B, Biointerfaces 2017 Oct 1;158:527-538
Effects of pharmacological inhibition of plasminogen binding on liver regeneration in rats.
Miura A, Ishiguro K, Koizumi K, Yaita Y, Ozaki-Masuzawa Y, Hosono T, Seki T
Bioscience, biotechnology, and biochemistry 2017 Nov;81(11):2105-2111
Bioscience, biotechnology, and biochemistry 2017 Nov;81(11):2105-2111
The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells.
Itoh M, Radisky DC, Hashiguchi M, Sugimoto H
Oncotarget 2017 Nov 3;8(54):92157-92170
Oncotarget 2017 Nov 3;8(54):92157-92170
Radioprotective effect of ursolic acid in radiation-induced impairment of neurogenesis, learning and memory in adolescent BALB/c mouse.
Tang FR, Loke WK, Wong P, Khoo BC
Physiology & behavior 2017 Jun 1;175:37-46
Physiology & behavior 2017 Jun 1;175:37-46
Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis.
Kijani S, Vázquez AM, Levin M, Borén J, Fogelstrand P
Physiological reports 2017 Jul;5(14)
Physiological reports 2017 Jul;5(14)
Ramelteon, a selective MT1/MT2 receptor agonist, suppresses the proliferation and invasiveness of endometrial cancer cells.
Osanai K, Kobayashi Y, Otsu M, Izawa T, Sakai K, Iwashita M
Human cell 2017 Jul;30(3):209-215
Human cell 2017 Jul;30(3):209-215
Possible role of mitochondrial injury in Caulis Aristolochia manshuriensis-induced chronic aristolochic acid nephropathy.
Liu X, Wu J, Wang J, Fan J, Feng X, Yu X, Yang X
Drug and chemical toxicology 2017 Jan;40(1):115-124
Drug and chemical toxicology 2017 Jan;40(1):115-124
Serotonin receptor 4 (5-hydroxytryptamine receptor Type 4) regulates expression of estrogen receptor beta and cell migration in hormone-naive prostate cancer.
Nakamura Y, Ise K, Yamazaki Y, Fujishima F, McNamara KM, Sasano H
Indian journal of pathology & microbiology 2017 Jan-Mar;60(1):33-37
Indian journal of pathology & microbiology 2017 Jan-Mar;60(1):33-37
Reprogramming-derived gene cocktail increases cardiomyocyte proliferation for heart regeneration.
Cheng YY, Yan YT, Lundy DJ, Lo AH, Wang YP, Ruan SC, Lin PJ, Hsieh PC
EMBO molecular medicine 2017 Feb;9(2):251-264
EMBO molecular medicine 2017 Feb;9(2):251-264
Improved Proliferative Capacity of NP-Like Cells Derived from Human Mesenchymal Stromal Cells and Neuronal Transdifferentiation by Small Molecules.
Aguilera-Castrejon A, Pasantes-Morales H, Montesinos JJ, Cortés-Medina LV, Castro-Manrreza ME, Mayani H, Ramos-Mandujano G
Neurochemical research 2017 Feb;42(2):415-427
Neurochemical research 2017 Feb;42(2):415-427
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.
Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Paszek M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 21;114(8):E1432-E1440
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 21;114(8):E1432-E1440
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M
Cancer cell 2017 Dec 11;32(6):824-839.e8
Cancer cell 2017 Dec 11;32(6):824-839.e8
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
Wang LT, Chiou SS, Chai CY, Hsi E, Chiang CM, Huang SK, Wang SN, Yokoyama KK, Hsu SH
Oncogene 2017 Aug;36(31):4405-4414
Oncogene 2017 Aug;36(31):4405-4414
Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.
Chen HC, Chin YF, Lundy DJ, Liang CT, Chi YH, Kuo P, Hsieh PCH
Scientific reports 2017 Aug 7;7(1):7372
Scientific reports 2017 Aug 7;7(1):7372
Age-dependent development of liver fibrosis in Glmp (gt/gt) mice.
Nesset CK, Kong XY, Damme M, Schjalm C, Roos N, Løberg EM, Eskild W
Fibrogenesis & tissue repair 2016;9:5
Fibrogenesis & tissue repair 2016;9:5
Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2-p53 signaling.
Xie C, Wu B, Chen B, Shi Q, Guo J, Fan Z, Huang Y
OncoTargets and therapy 2016;9:4005-13
OncoTargets and therapy 2016;9:4005-13
The Role of Butylidenephthalide in Targeting the Microenvironment Which Contributes to Liver Fibrosis Amelioration.
Chuang HM, Su HL, Li C, Lin SZ, Yen SY, Huang MH, Ho LI, Chiou TW, Harn HJ
Frontiers in pharmacology 2016;7:112
Frontiers in pharmacology 2016;7:112
mTOR Overactivation in Mesenchymal cells Aggravates CCl4- Induced liver Fibrosis.
Shan L, Ding Y, Fu Y, Zhou L, Dong X, Chen S, Wu H, Nai W, Zheng H, Xu W, Bai X, Jia C, Dai M
Scientific reports 2016 Nov 7;6:36037
Scientific reports 2016 Nov 7;6:36037
ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation.
de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E
Nature communications 2016 May 17;7:11551
Nature communications 2016 May 17;7:11551
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.
Murai K, Sun G, Ye P, Tian E, Yang S, Cui Q, Sun G, Trinh D, Sun O, Hong T, Wen Z, Kalkum M, Riggs AD, Song H, Ming GL, Shi Y
Nature communications 2016 Mar 11;7:10965
Nature communications 2016 Mar 11;7:10965
Effects of Oxymatrine on the Proliferation and Apoptosis of Human Hepatoma Carcinoma Cells.
Liu Y, Bi T, Dai W, Wang G, Qian L, Gao Q, Shen G
Technology in cancer research & treatment 2016 Jun;15(3):487-97
Technology in cancer research & treatment 2016 Jun;15(3):487-97
Src as a Therapeutic Target in Biliary Tract Cancer.
Nam AR, Kim JW, Park JE, Bang JH, Jin MH, Lee KH, Kim TY, Han SW, Im SA, Kim TY, Oh DY, Bang YJ
Molecular cancer therapeutics 2016 Jul;15(7):1515-24
Molecular cancer therapeutics 2016 Jul;15(7):1515-24
Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer.
Yuan B, Cheng L, Gupta K, Chiang HC, Gupta HB, Sareddy GR, Wang D, Lathrop K, Elledge R, Wang P, McHardy S, Vadlamudi R, Curiel TJ, Hu Y, Ye Q, Li R
Oncotarget 2016 Jul 5;7(27):42585-42597
Oncotarget 2016 Jul 5;7(27):42585-42597
TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway.
Gan Y, Wang Y, Tan Z, Zhou J, Kitazawa R, Jiang X, Tang Y, Yang J
Cancer biology & therapy 2016 Jul 2;17(7):741-50
Cancer biology & therapy 2016 Jul 2;17(7):741-50
Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
Liu Y, Bi T, Wang Z, Wu G, Qian L, Gao Q, Shen G
Apoptosis : an international journal on programmed cell death 2016 Dec;21(12):1398-1407
Apoptosis : an international journal on programmed cell death 2016 Dec;21(12):1398-1407
A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71.
Liou AT, Wu SY, Liao CC, Chang YS, Chang CS, Shih C
Scientific reports 2016 Aug 8;6:31151
Scientific reports 2016 Aug 8;6:31151
MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1.
Liu XY, Liu ZJ, He H, Zhang C, Wang YL
American journal of cancer research 2015;5(10):3015-29
American journal of cancer research 2015;5(10):3015-29
Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.
Lan T, Kisseleva T, Brenner DA
PloS one 2015;10(7):e0129743
PloS one 2015;10(7):e0129743
Filter-Dense Multicolor Microscopy.
Kijani S, Yrlid U, Heyden M, Levin M, Borén J, Fogelstrand P
PloS one 2015;10(3):e0119499
PloS one 2015;10(3):e0119499
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
Tandon M, Salamoun JM, Carder EJ, Farber E, Xu S, Deng F, Tang H, Wipf P, Wang QJ
PloS one 2015;10(3):e0119346
PloS one 2015;10(3):e0119346
Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish.
Chou CM, Chen YC, Su S, Chen GD, Huang KY, Lien HW, Huang CJ, Cheng CH
Journal of biomedical science 2015 Nov 17;22:102
Journal of biomedical science 2015 Nov 17;22:102
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress.
Antonucci L, Fagman JB, Kim JY, Todoric J, Gukovsky I, Mackey M, Ellisman MH, Karin M
Proceedings of the National Academy of Sciences of the United States of America 2015 Nov 10;112(45):E6166-74
Proceedings of the National Academy of Sciences of the United States of America 2015 Nov 10;112(45):E6166-74
A gp130-Src-YAP module links inflammation to epithelial regeneration.
Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M
Nature 2015 Mar 5;519(7541):57-62
Nature 2015 Mar 5;519(7541):57-62
A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis.
Abraham S, Scarcia M, Bagshaw RD, McMahon K, Grant G, Harvey T, Yeo M, Esteves FOG, Thygesen HH, Jones PF, Speirs V, Hanby AM, Selby PJ, Lorger M, Dear TN, Pawson T, Marshall CJ, Mavria G
Nature communications 2015 Jul 1;6:7286
Nature communications 2015 Jul 1;6:7286
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.
Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, Zhong Z, Valasek MA, Seki E, Hidalgo J, Koike K, Kaufman RJ, Karin M
Cancer cell 2014 Sep 8;26(3):331-343
Cancer cell 2014 Sep 8;26(3):331-343
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.
Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 23;111(38):13870-5
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 23;111(38):13870-5
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model.
Murai K, Qu Q, Sun G, Ye P, Li W, Asuelime G, Sun E, Tsai GE, Shi Y
Proceedings of the National Academy of Sciences of the United States of America 2014 Jun 24;111(25):9115-20
Proceedings of the National Academy of Sciences of the United States of America 2014 Jun 24;111(25):9115-20
Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.
Li KC, Hua KT, Lin YS, Su CY, Ko JY, Hsiao M, Kuo ML, Tan CT
Molecular cancer 2014 Jul 15;13:172
Molecular cancer 2014 Jul 15;13:172
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 21;111(3):1090-5
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 21;111(3):1090-5
The commonly used antimicrobial additive triclosan is a liver tumor promoter.
Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 2;111(48):17200-5
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 2;111(48):17200-5
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.
Wang K, Kim MK, Di Caro G, Wong J, Shalapour S, Wan J, Zhang W, Zhong Z, Sanchez-Lopez E, Wu LW, Taniguchi K, Feng Y, Fearon E, Grivennikov SI, Karin M
Immunity 2014 Dec 18;41(6):1052-63
Immunity 2014 Dec 18;41(6):1052-63
MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.
Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, Zeng Y, Sun B, Qian H, Chen L, Wu M, Su C, Chen J
Cancer letters 2013 Sep 1;337(2):226-36
Cancer letters 2013 Sep 1;337(2):226-36
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11).
Chen S, Yueh MF, Bigo C, Barbier O, Wang K, Karin M, Nguyen N, Tukey RH
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 19;110(47):19143-8
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 19;110(47):19143-8
Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction.
Chen CH, Wang SS, Wei EI, Chu TY, Hsieh PC
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Mar;21(3):670-9
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Mar;21(3):670-9
Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation.
Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough BR, Lunz JG, Murase N, Yokota S, Demetris AJ
The American journal of pathology 2013 Jan;182(1):180-91
The American journal of pathology 2013 Jan;182(1):180-91
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.
Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, Taniguchi K, Yu GY, Osterreicher CH, Hung KE, Datz C, Feng Y, Fearon ER, Oukka M, Tessarollo L, Coppola V, Yarovinsky F, Cheroutre H, Eckmann L, Trinchieri G, Karin M
Nature 2012 Nov 8;491(7423):254-8
Nature 2012 Nov 8;491(7423):254-8
Differentiation profile of peripheral blood-derived vascular progenitor cell predicts intimal hyperplasia after coronary stenting.
Wang CH, Hsieh IC, Cherng WJ, Chen CC, Tung TH, Lee JF, Lin SJ, Wang PN
Heart and vessels 2012 Jan;27(1):10-9
Heart and vessels 2012 Jan;27(1):10-9
Suppression of autoimmune diabetes by soluble galectin-1.
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Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2641-53
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2641-53
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- Human Lung Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Immunohistochemical staining using Ki-67 antibody
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- Formalin fixed paraffin embedded human tonsil stained with Ki-67 antibody (GTX16667)
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- Human Tonsil stained with anti-Ki-67 antibody (GTX16667)
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- Human Bladder Transitional Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Esophagus stained with anti-Ki-67 antibody (GTX16667)
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- Human Fallopian Tube stained with anti-Ki-67 antibody (GTX16667)
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- Human Endometrial Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Cervical Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Skin Squamous Cell Carcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Hepatocellular Carcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Stomach Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Skin stained with anti-Ki-67 antibody (GTX16667)
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- Human Thymus stained with anti-Ki-67 antibody (GTX16667)
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- Human Spleen stained with anti-Ki-67 antibody (GTX16667)
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- Human Spinal Cord stained with anti-Ki-67 antibody (GTX16667)
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- Human Stomach stained with anti-Ki-67 antibody (GTX16667)
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- Human Liver stained with anti-Ki-67 antibody (GTX16667)
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- Human Prostate stained with anti-Ki-67 antibody (GTX16667)
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- Human Lung stained with anti-Ki-67 antibody (GTX16667)
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- Human Lung Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Lymph Node stained with anti-Ki-67 antibody (GTX16667)
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- Human Prostate Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Testis stained with anti-Ki-67 antibody (GTX16667)
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- Human B Cell Lymphoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Thyroid stained with anti-Ki-67 antibody (GTX16667)
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- Human HK Lymphoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Colon stained with anti-Ki-67 antibody (GTX16667)
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- Human Colon Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Human Breast stained with anti-Ki-67 antibody (GTX16667)
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- Human Breast Adenocarcinoma stained with anti-Ki-67 antibody (GTX16667)
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- Ki67 antibody [SP6] detects Ki67 protein at nucleus in human cervical metaplasia (left) and carcinoma (right) by immunohistochemical analysis. Sample: Paraffin-embedded human cervix. Ki67 antibody [SP6] (GTX16667) diluted at 1:200.