Antibody data
- Antibody Data
- Antigen structure
- References [770]
- Comments [0]
- Validations
- Immunocytochemistry [2]
- Immunohistochemistry [6]
- Flow cytometry [1]
- Other assay [4]
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Validation data
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- Product number
- MA5-14520 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- Staining of formalin-fixed tissues requires boiling tissue section in 10 mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes. Recommended positive controls: IHC (P) - Human tonsil and testis tissue, common marmoset spleen tissue, rat esophagus, small intestine and liver tissue, mouse embryonic skin tissue IHC (F) - Rat lymph node tissue, transgenic mouse spinal cord tissue ICC/IF - HAP1 cells, human cardiac stem cells, HEp-2 cells, rat cardiomyocytes Flow - HAP1 cells
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Antibody clone number
- SP6
- Vial size
- 500 µL
- Concentration
- 0.031 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Decellularization of xenografted tumors provides cell-specific in vitro 3D environment.
InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Expression and Prognostic Value of Melanoma-Associated Antigen D2 in Gliomas.
Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types.
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.
Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10.
DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice.
Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling.
The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition.
Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes.
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Generation and functional characterization of murine mammary organoids.
Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes.
Sexual dimorphisms in brain gene expression in the growth-restricted guinea pig can be modulated with intra-placental therapy.
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.
Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC.
Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.
Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo.
Insulin-like growth factor 1 promotes the extension of Tracheal Epithelium in an in Vitro Tracheal organ culture model.
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.
Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction.
EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis.
STRADA-mutant human cortical organoids model megalencephaly and exhibit delayed neuronal differentiation.
Rapid Prototyping of Multilayer Microphysiological Systems.
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
A constant pool of Lgr5(+) intestinal stem cells is required for intestinal homeostasis.
TNFα promotes oral cancer growth, pain, and Schwann cell activation.
Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer.
Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis.
Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance.
Immunohistochemical evaluation of hepatic progenitor cells in different types of feline liver diseases.
miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis.
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Histological and Immunohistochemical Characterization of Vomeronasal Organ Aging in Mice.
Evidence and manipulation of O-GlcNAcylation in granulosa cells of bovine antral follicles†.
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation.
IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.
Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis.
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.
High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.
RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5.
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.
Secondary ossification center induces and protects growth plate structure.
Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.
Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors.
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice.
Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk.
The secretome of human dental pulp stem cells protects myoblasts from hypoxia‑induced injury via the Wnt/β‑catenin pathway.
Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis.
Silencing of long‑chain non‑coding RNA GAS5 in osteoarthritic chondrocytes is mediated by targeting the miR‑34a/Bcl‑2 axis.
Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.
Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice.
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease.
Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.
Long-term PM(2.5) exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis.
Optic vesicle morphogenesis requires primary cilia.
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression.
Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.
The sialyltransferase ST6GAL1 protects against radiation-induced gastrointestinal damage.
Novel CD11b(+)Gr-1(+)Sca-1(+) myeloid cells drive mortality in bacterial infection.
An intrinsic role of IL-33 in T(reg) cell-mediated tumor immunoevasion.
Loss of Setd4 delays radiation-induced thymic lymphoma in mice.
AQP5 enriches for stem cells and cancer origins in the distal stomach.
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Immune Modulation to Improve Survival of Viral Pneumonia in Mice.
Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro.
Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice.
Long non-coding RNA RFPL3S is a novel prognostic biomarker in lung cancer.
Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models.
Positive Effects of Preventive Nutrition Supplement on Anticancer Radiotherapy in Lung Cancer Bearing Mice.
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Yolk-sac-derived macrophages progressively expand in the mouse kidney with age.
A Novel Approach to Deliver Therapeutic Extracellular Vesicles Directly into the Mouse Kidney via Its Arterial Blood Supply.
Preclinical efficacy of hK2 targeted [(177)Lu]hu11B6 for prostate cancer theranostics.
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.
RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.
Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.
Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea.
Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Developmental changes in interkinetic nuclear migration dynamics with respect to cell-cycle progression in the mouse cerebral cortex ventricular zone.
Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells.
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Combination of laser and human adipose-derived stem cells in repair of rabbit anal sphincter injury: a new therapeutic approach.
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis.
The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats.
Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice.
Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation.
Development of a murine intravesical orthotopic human bladder cancer (mio-hBC) model.
Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli.
UXT is required for spermatogenesis in mice.
Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.
Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators.
The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression.
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.
Luteinizing hormone compromises the in vivo anti-tumor effect of cisplatin on human epithelial ovarian cancer cells.
Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.
Therapeutic Targeting of Sunitinib-Induced AR Phosphorylation in Renal Cell Carcinoma.
Low-dose statin treatment increases prostate cancer aggressiveness.
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.
HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.
A new genetically engineered mouse model of choroid plexus carcinoma.
Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.
Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance.
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.
Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice.
Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model.
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.
Kctd13 deletion reduces synaptic transmission via increased RhoA.
Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response.
Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.
Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.
Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.
In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents.
GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis.
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.
Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.
Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.
Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.
FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
miR-342-5p Regulates Neural Stem Cell Proliferation and Differentiation Downstream to Notch Signaling in Mice.
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice.
High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques.
IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.
Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells.
Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers.
Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique.
Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus.
Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease.
A challenging case of ocular melanoma.
Missense Mutations in Exons 18-24 of EGFR in Hepatocellular Carcinoma Tissues.
Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.
KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice.
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.
Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region.
The effect of pomegranate fruit extract on testosterone-induced BPH in rats.
Does the WHO 2010 classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas?
Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture.
Castration-resistant Lgr5(+) cells are long-lived stem cells required for prostatic regeneration.
P16(INK 4a) and Ki-67 expression in human papilloma virus-related head and neck mucosal lesions.
Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma--a clinical, histologic and immunohistochemical study.
Site-specific programming of the host epithelial transcriptome by the gut microbiota.
Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity.
In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.
Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.
Combination strategy targeting VEGF and HGF/c-met in human renal cell carcinoma models.
p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.
Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy.
Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.
Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Retrospective analysis of metastatic behaviour of breast cancer subtypes.
IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment.
Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI.
Novel epigenetic target therapy for prostate cancer: a preclinical study.
Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin.
Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.
Conditioned medium from hypoxic bone marrow-derived mesenchymal stem cells enhances wound healing in mice.
Effects of siRNA on RET/PTC3 junction oncogene in papillary thyroid carcinoma: from molecular and cellular studies to preclinical investigations.
Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.
Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline.
Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas.
Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.
Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids.
n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice.
High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice.
μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche.
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.
Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.
The kidney is the principal organ mediating klotho effects.
The kinetics of ER fusion protein activation in vivo.
Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.
Histone deacetylase expression in white matter oligodendrocytes after stroke.
Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.
WFDC1 is a key modulator of inflammatory and wound repair responses.
CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.
Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance.
RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
Activation of cutaneous immune responses in complex regional pain syndrome.
The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
High-risk human papillomavirus load and biomarkers in cervical intraepithelial neoplasia and cancer.
Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury.
Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation.
CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways.
Cells of renin lineage take on a podocyte phenotype in aging nephropathy.
Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival.
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Degeneration, regeneration, and cicatrization after fat grafting: dynamic total tissue remodeling during the first 3 months.
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.
DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells.
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast.
The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas.
Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values.
Culture dimensionality influences the resistance of glioblastoma stem-like cells to multikinase inhibitors.
Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.
Differentiation and histogenesis of syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: evidence for a common origin.
Characterization of the 9L gliosarcoma implanted in the Fischer rat: an orthotopic model for a grade IV brain tumor.
Constructs of electrospun PLGA, compressed collagen and minced urothelium for minimally manipulated autologous bladder tissue expansion.
Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.
CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.
Contribution of mesenchymal proliferation in tooth root morphogenesis.
Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells.
AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.
Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.
Evaluation of Ki-67 index in EUS-FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors.
Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations.
Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver.
Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.
Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine.
FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.
P53-participated cellular and molecular responses to irradiation are cell differentiation-determined in murine intestinal epithelium.
Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration.
NANOS2 promotes male germ cell development independent of meiosis suppression.
G0-G1 transition and the restriction point in pancreatic β-cells in vivo.
Immunohistochemical distribution of cell cycle proteins p27, p57, cyclin D3, PCNA and Ki67 in normal and diabetic human placentas.
MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.
Solitary tumours associated with Jaagsiekte retrovirus in sheep are heterogeneous and contain cells expressing markers identifying progenitor cells in lung repair.
Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration.
Expression of a Y-located human proto-oncogene TSPY in a transgenic mouse model of prostate cancer.
Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.
Birthdating of myenteric neuron subtypes in the small intestine of the mouse.
Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.
Tumor vascularization is critical for oncolytic vaccinia virus treatment of peritoneal carcinomatosis.
Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche.
Temsirolimus combined with cisplatin or bevacizumab is active in osteosarcoma models.
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
MET expression is associated with disease-specific survival in breast cancer patients in the neoadjuvant setting.
MYC synergizes with activated BRAFV600E in mouse lung tumor development by suppressing senescence.
Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype.
Bronchiolar remodeling in adult mice following neonatal exposure to hyperoxia: relation to growth.
Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex.
Immunolocalization of cell cycle proteins (p57, p27, cyclin D3, PCNA and Ki67) in intrauterine growth retardation (IUGR) and normal human term placentas.
Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1α,25(OH)2 and 25(OH) vitamin D.
Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury.
An integrated computational/experimental model of lymphoma growth.
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.
TLR2 mediates Helicobacter pylori-induced tolerogenic immune response in mice.
Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells.
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
Multiple delivery of siRNA against endoglin into murine mammary adenocarcinoma prevents angiogenesis and delays tumor growth.
Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2.
CoupTFI interacts with retinoic acid signaling during cortical development.
Tissue engineered skin substitutes created by laser-assisted bioprinting form skin-like structures in the dorsal skin fold chamber in mice.
Tumor stress-induced phosphoprotein1 (STIP1) as a prognostic biomarker in ovarian cancer.
Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis.
Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats.
Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.
Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.
Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.
Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo.
A husband and a wife with simultaneous presentation of glioblastoma multiforme: a case report.
Insulinoma diagnosed as drug-refractory epilepsy in an adolescent boy: a case report.
APC/C-Cdh1 coordinates neurogenesis and cortical size during development.
Aldara activates TLR7-independent immune defence.
Enhanced oxygen supply improves islet viability in a new bioartificial pancreas.
Biological and demographic profile of meningiomas in a cohort of Egyptian patients: impact on tumor recurrence.
MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.
Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.
Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.
Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas.
Uterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.
Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.
Role of fibrinogen in acute ischemic kidney injury.
Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.
Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.
Lack of high-dose radiation mediated prostate cancer promotion and low-dose radiation adaptive response in the TRAMP mouse model.
Slow turning lateral vessel bioreactor improves embryoid body formation and cardiogenic differentiation of mouse embryonic stem cells.
Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases.
Is Ki-67 expression prognostic for local relapse in early-stage breast cancer patients treated with breast conservation therapy (BCT)?
Targeting 5-HT(1A) receptors in astrocytes to protect dopaminergic neurons in Parkinsonian models.
The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.
Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory.
The regulation of SOX7 and its tumor suppressive role in breast cancer.
FDG PET in the evaluation of phaeochromocytoma: a correlative study with MIBG scintigraphy and Ki-67 proliferative index.
Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.
The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells.
Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan.
Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.
Enhanced liver progenitor cell survival and differentiation in vivo by spheroid implantation in a vascularized tissue engineering chamber.
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development.
miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin α5 expression.
Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.
A novel model of adenine-induced tubulointerstitial nephropathy in mice.
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus.
Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome.
Dynamics of senescent cell formation and retention revealed by p14ARF induction in the epidermis.
Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.
Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.
VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain.
Is survivin expression prognostic or predictive in malignant pleural mesothelioma?
An in vivo screen of secreted proteins identifies adiponectin as a regulator of murine cutaneous wound healing.
Role of Langerhans cells, Ki-67 protein and apoptosis in acquired cholesteatoma: prospective clinical study.
Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies.
Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice.
The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes.
Chemoprevention of lung squamous cell carcinoma by ginseng.
Signature patterns of human papillomavirus type 16 in invasive anal carcinoma.
Transcription factor Sox11 is essential for both embryonic and adult neurogenesis.
Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer.
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.
Expression of Lewis X is associated with poor prognosis in triple-negative breast cancer.
Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosis.
FGFR1 is essential for prostate cancer progression and metastasis.
Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS.
State-dependent signaling by Cav1.2 regulates hair follicle stem cell function.
Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells.
SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein.
Characterization of WWOX inactivation in murine mammary gland development.
Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors.
The effects of ulipristal on Bax/Bcl-2, cytochrome c, Ki-67 and cyclooxygenase-2 expression in a rat model with surgically induced endometriosis.
Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells.
Changes in signaling pathways induced by vandetanib in a human medullary thyroid carcinoma model, as analyzed by reverse phase protein array.
Lithium rescues synaptic plasticity and memory in Down syndrome mice.
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord.
Expression of matrix metalloproteinase-13 and Ki-67 in nonmelanoma skin cancer in xeroderma pigmentosum and non-xeroderma pigmentosum.
MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.
Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.
eIF4F suppression in breast cancer affects maintenance and progression.
Local insulin application on the carotid artery inhibits neointima formation.
In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer.
Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.
PTEN loss mitigates the response of medulloblastoma to Hedgehog pathway inhibition.
Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice.
Systemic regulation of the age-related decline of pancreatic β-cell replication.
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
K5/K14-positive cells contribute to salivary gland-like breast tumors with myoepithelial differentiation.
Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.
Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models.
Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice.
Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
Combination therapy of cilengitide with belotecan against experimental glioblastoma.
Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.
The PPARγ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.
Adenovirus-mediated interferon-γ gene therapy induced human pancreatic carcinoma Capan-2 cell apoptosis in vitro and in vivo.
Specimen quality evaluation in Canadian biobanks participating in the COEUR repository.
Hepatic regeneration and functional recovery following partial liver resection in an experimental model of hepatic steatosis treated with omega-3 fatty acids.
Proliferation and cell cycle dynamics in the developing stellate ganglion.
Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis.
Effects of steroid hormones on differentiated glandular epithelial and stromal cells in a three dimensional cell culture model of the canine endometrium.
Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.
Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution.
Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.
Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.
An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.
Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression.
Cauda equina paraganglioma with ependymoma-like histology: a case report.
Fates of murine pluripotent stem cell-derived neural progenitors following transplantation into mouse cochleae.
A crucial role of bone morphogenetic protein signaling in the wound healing response in acute liver injury induced by carbon tetrachloride.
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.
Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence.
Oxidative stress gradient in a medium during human corneal organ culture.
Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.
Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.
MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.
MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.
Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.
Somatotroph pituitary adenoma with acromegaly and autosomal dominant polycystic kidney disease: SSTR5 polymorphism and PKD1 mutation.
Rgs19 regulates mouse palatal fusion by modulating cell proliferation and apoptosis in the MEE.
WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.
Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia.
Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer.
Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.
Testis development requires the repression of Wnt4 by Fgf signaling.
Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction.
Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas.
Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation.
Radioimmunotherapy of fibroblast activation protein positive tumors by rapidly internalizing antibodies.
Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments.
Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.
Activation of neural progenitor cells in human eyes with proliferative vitreoretinopathy.
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity.
Is primary pulmonary meningioma a giant form of a meningothelial-like nodule? A case report and review of the literature.
The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.
Increased FDG uptake in breast cancer is associated with prognostic factors.
Bimodal effect of retinoic acid on melanocyte differentiation identified by time-dependent analysis.
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.
Targeting colorectal cancer stem cells with inducible caspase-9.
Functional consequences of human airway smooth muscle phenotype plasticity.
IL-12 and IL-23 affect photocarcinogenesis differently.
Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase.
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.
PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.
Expression and activation of EphA4 in the human brain after traumatic injury.
Early onset of endothelial cell proliferation in coronary thrombi of patients with an acute myocardial infarction: implications for plaque healing.
Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice.
De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy.
The effects of intrauterine growth restriction and antenatal glucocorticoids on ovine fetal lung development.
Effect of staged ovariectomy on measures of mammary growth and development in prepubertal dairy heifers.
Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients.
Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.
YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.
Pigmented paraganglioma of the kidney: a case report.
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.
Effects of acrylamide exposure on serum hormones, gene expression, cell proliferation, and histopathology in male reproductive tissues of Fischer 344 rats.
Collective action of hematopoietic cell subsets mediates anti-IL10R1 and CpG tumor immunity.
Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice.
The adult pituitary shows stem/progenitor cell activation in response to injury and is capable of regeneration.
No harmful effect of mycophenolate mofetil on liver regeneration: an experimental study.
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
Nanostructured porous silicon micropatterns as a tool for substrate-conditioned cell research.
Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
Primary pure squamous cell carcinoma of the thyroid: report and histogenic consideration of a case involving a BRAF mutation.
Early changes in carcinogenesis of colorectal adenomas.
Early changes in carcinogenesis of colorectal adenomas.
Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.
Cell signaling pathways associated with a reduction in mammary cancer burden by dietary common bean (Phaseolus vulgaris L.).
The prognostic value of Skp2 expression in Egyptian diffuse large B-cell lymphoma.
Quantitative assessment of liver function after ischemia-reperfusion injury and partial hepatectomy in rats.
Failure of delayed intravenous administration of bone marrow stromal cells after traumatic brain injury.
Insights antifibrotic mechanism of methyl palmitate: impact on nuclear factor kappa B and proinflammatory cytokines.
Honey as a substitute for formalin?
Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.
Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model.
Increased adult hippocampal neurogenesis and abnormal migration of adult-born granule neurons is associated with hippocampal-specific cognitive deficits in phospholipase C-β1 knockout mice.
Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation.
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
Evaluation of apoptosis along with BCL-2 and Ki-67 expression in patients with intestinal metaplasia.
An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells.
Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo.
Differential function of NBS1 and ATR in neurogenesis.
Evidence of mTOR Activation by an AKT-Independent Mechanism Provides Support for the Combined Treatment of PTEN-Deficient Prostate Tumors with mTOR and AKT Inhibitors.
BCL10 down-regulation in peripheral T-cell lymphomas.
Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors.
Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis.
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.
Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues.
Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals.
Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors.
Regenerative capacity of the adult pituitary: multiple mechanisms of lactotrope restoration after transgenic ablation.
Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx).
Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids.
Intermediate progenitors are increased by lengthening of the cell cycle through calcium signaling and p53 expression in human neural progenitors.
Antitumor effects of cis-urocanic acid on experimental urothelial cell carcinoma of the bladder.
Overexpression of cathepsin S induces chronic atopic dermatitis in mice.
KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer.
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
Tumor Vascular Morphology Undergoes Dramatic Changes during Outgrowth of B16 Melanoma While Proangiogenic Gene Expression Remains Unchanged.
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.
Early cyst growth is associated with the increased nuclear expression of cyclin D1/Rb protein in an autosomal-recessive polycystic kidney disease rat model.
Cytogenetic analysis of a malignant triton tumour by comparative genomic hybridization (CGH) and review of the literature.
Kidney spheroids recapitulate tubular organoids leading to enhanced tubulogenic potency of human kidney-derived cells.
Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth by increasing apoptosis.
Restrictions that control herpes simplex virus type 1 infection in mouse brain ex vivo.
Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.
Molecular phenotypes of matched in situ and invasive components of breast carcinomas.
Influence of heparan sulfate chains in proteoglycan at the dermal-epidermal junction on epidermal homeostasis.
Expression of fascin protein and mRNA in the KB carcinoma cell line following treatment with doxorubicin.
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis.
Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas.
Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival.
Endothelium-coated tumor clusters are associated with poor prognosis and micrometastasis of hepatocellular carcinoma after resection.
High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.
Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.
Development of skin-humanized mouse models of pachyonychia congenita.
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies.
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Endogenous Myc maintains the tumor microenvironment.
A comparative immunohistochemical analysis of COX-2, p53, and Ki-67 expression in keratocystic odontogenic tumors.
Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model.
The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model.
Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.
Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells.
Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.
Gastrointestinal stromal tumours in children and young adults: a clinicopathologic series with long-term follow-up from the database of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Usefulness of p16ink4a, ProEX C, and Ki-67 for the diagnosis of glandular dysplasia and adenocarcinoma of the cervix uteri.
Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.
Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer.
Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.
X-irradiation reduces the proliferation of astrocytes by cell cycle arrest.
CDKN1B/p27 expression in peripheral T cell lymphoma not otherwise specified.
Analysis of the IgVH genes in T cell-mediated and antibody-mediated rejection of the kidney graft.
Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation.
Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice.
Quantitative assessment of hepatic function during liver regeneration in a standardized rat model.
Osteosarcoma arising in a long-standing uterine leiomyoma: a case report and literature review.
Ectopic endometrial tissue in mesonephric duct remnants in bitches.
Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.
Heat shock attenuates VEGF expression in three-dimensional myoblast sheets deteriorating therapeutic efficacy in heart failure.
The relationship among PDX1, CDX2, and mucin profiles in gastric carcinomas; correlations with clinicopathologic parameters.
Predicting IGF-1R therapy response in bone sarcomas: immuno-SPECT imaging with radiolabeled R1507.
Optic nerve gliomas: role of Ki-67 staining of tumour and margins in predicting long-term outcome.
Enhancement of in vitro human tubulogenesis by endothelial cell-derived factors: implications for in vivo tubular regeneration after injury.
Increased diagnostic accuracy of atypical glandular cells in cervical liquid-based cytology using cell blocks.
Lymphoepithelioma-like carcinoma of the ovary.
Validation of MdmX as a therapeutic target for reactivating p53 in tumors.
Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.
Tumour eosinophilia combined with an immunohistochemistry panel is useful in the differentiation of type B3 thymoma from thymic carcinoma.
Cyclooxygenase-2 supports tumor proliferation in vestibular schwannomas.
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.
Infrared radiation does not enhance the frequency of ultraviolet radiation-induced skin tumors, but their growth behaviour in mice.
Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?
Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target.
Autophagy-deficient mice develop multiple liver tumors.
Species differences in reactivity of mouse and rat astrocytes in vitro.
A comparison of Ki-67 antigen presentation in acute generalized exanthematous pustulosis and pustular psoriasis.
Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation.
Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth.
The role of keratinocyte growth factor in melanogenesis: a possible mechanism for the initiation of solar lentigines.
Antiangiogenic effect of licochalcone A.
111In-bevacizumab imaging of renal cell cancer and evaluation of neoadjuvant treatment with the vascular endothelial growth factor receptor inhibitor sorafenib.
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark.
Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231.
Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.
Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.
PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity.
A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.
TGF-beta1 causes epithelial-mesenchymal transition in HaCaT derivatives, but induces expression of COX-2 and migration only in benign, not in malignant keratinocytes.
Expression of Ki-67, PCNA, and p27kip1 in canine pituitary corticotroph adenomas.
Eph receptor tyrosine kinases regulate astrocyte cytoskeletal rearrangement and focal adhesion formation.
The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development.
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
Desmoplastic small round cell tumor of the submandibular gland--a rare but distinctive primary salivary gland neoplasm.
Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management.
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment.
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.
Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos.
Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase.
What would be left behind if subtotal thyroidectomy were preferred instead of total thyroidectomy?
Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome.
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis.
Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.
Thyroid transcription factor-1 influences the early phase of compensatory lung growth in adult mice.
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure.
Evaluation of clinico-pathological criteria and the Ki67 index as prognostic indicators in canine insulinoma.
Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report.
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.
A class discovery and class prediction approach to histopathological classification of mammographic screen detected columnar cell lesions of the breast.
Synchronous presentation of GISTs and other primary neoplasms: a single center experience.
Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
High-precision radiosurgical dose delivery by interlaced microbeam arrays of high-flux low-energy synchrotron X-rays.
Diagnostic value of p16INK4A, Ki-67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens.
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.
Extraribosomal function of metallopanstimulin-1: reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growth.
Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo.
Evaluation of the presence of Helicobacter species in the biliary system of Turkish patients with cholelithiasis.
Immuno-histochemical evaluation of solar lentigines: The association of KGF/KGFR and other factors with lesion development.
Acute ANIT toxicity in male IL-10 knockout and wild-type mice.
S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer.
Heparanase expression of glioma in human and animal models.
Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells.
The pathogenic role of Epstein-Barr virus (EBV) in sclerosing polycystic adenosis.
Therapeutic antibody targeting of individual Notch receptors.
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.
Soy consumption and histopathologic markers in breast tissue using tissue microarrays.
Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.
Ki-67 in screen-detected, low-grade, low-stage prostate cancer, relation to prostate-specific antigen doubling time, Gleason score and prostate-specific antigen relapse after radical prostatectomy.
Dicer is required for maintaining adult pancreas.
Effect of yeast-derived beta-glucan in conjunction with bevacizumab for the treatment of human lung adenocarcinoma in subcutaneous and orthotopic xenograft models.
Cross-species immunohistochemical investigation of the activation of the liver progenitor cell niche in different types of liver disease.
Immunohistochemical expression of SPARC is correlated with recurrence, survival and malignant potential in meningiomas.
A 19-year follow-up of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome who developed non-Hodgkin lymphoma.
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Gender differences in pulmonary regenerative response to naphthalene-induced bronchiolar epithelial cell injury.
Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence.
Leukemia inhibitory factor favours neurogenic differentiation of long-term propagated human midbrain precursor cells.
Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.
Predicting recurrence of nonfunctioning pituitary adenomas.
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer.
Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles.
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions.
Tumour control by whole brain irradiation of anti-VEGF-treated mice bearing intracerebral glioma.
Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
In pursuit of leucine-rich repeat-containing G protein-coupled receptor-5 regulation and function in the uterus.
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
Synchrotron microbeam radiation therapy for rat brain tumor palliation-influence of the microbeam width at constant valley dose.
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).
Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa: age-related progression.
Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation.
Energetics and mammary carcinogenesis: effects of moderate-intensity running and energy intake on cellular processes and molecular mechanisms in rats.
Prognostic significance of oncogenic markers in ductal carcinoma in situ of the breast: a clinicopathologic study.
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.
Amplification of the urokinase-type plasminogen activator receptor (uPAR) gene in ductal pancreatic carcinomas identifies a clinically high-risk group.
Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.
Mammographic density and epithelial histopathologic markers.
Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.
Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer.
Apoptosis-related (survivin, Bcl-2), tumor suppressor gene (p53), proliferation (Ki-67), and non-receptor tyrosine kinase (Src) markers expression and correlation with clinicopathologic variables in 60 thymic neoplasms.
Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.
A limited panel of immunomarkers can reliably distinguish between clear cell and high-grade serous carcinoma of the ovary.
Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo.
Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice.
EphA2 as a promoter of melanoma tumorigenicity.
EphA2 as a promoter of melanoma tumorigenicity.
Cypermethrin effects on the adult mice seminal glands.
Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.
FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions.
Role of the microenvironment for radiosensitization by patupilone.
Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide.
Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice.
Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation.
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice.
Prolactin treatment improves engraftment and function of transplanted pancreatic islets.
Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.
Craniofacial malformation in R-spondin2 knockout mice.
Plasmoblastic lymphoma associated with human immunodeficiency virus.
Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study.
Serdin1/Lrrc10 is dispensable for mouse development.
Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions.
Activated Akt as an indicator of prognosis in gastric cancer.
Coordinated expression of activated mitogen-activated protein kinases in salivary gland adenoid cystic carcinoma.
Mechanisms associated with dose-dependent inhibition of rat mammary carcinogenesis by dry bean (Phaseolus vulgaris, L.).
Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment.
Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver.
Effect of leukemia inhibitory factor on long-term propagation of precursor cells derived from rat forebrain subventricular zone and ventral mesencephalon.
The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.
Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment.
Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.
Bone marrow-derived cells expressing Iba1 are constitutively present as resident tissue macrophages in the mouse cochlea.
Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.
Human ASH1 expression in prostate cancer with neuroendocrine differentiation.
Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.
Expression of NANOG, but not POU5F1, points to the stem cell potential of primitive germ cells in neonatal pig testis.
Down-regulation of Notch signaling during corneal epithelial proliferation.
HDAC4 inhibits cell-cycle progression and protects neurons from cell death.
Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy.
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Applications of laser scanning cytometry in immunohistochemistry and routine histopathology.
Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway.
Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma.
Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy.
Chronic microcystin exposure induces hepatocyte proliferation with increased expression of mitotic and cyclin-associated genes in P53-deficient mice.
Regeneration with proliferation of the endothelium of cultured human donor corneas with extended postmortem time.
Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis.
Pulmonary arterial remodeling induced by a Th2 immune response.
An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis.
Immunohistochemical and ultrastructural characterization of brain tumors in S100beta-v-erbB transgenic rats.
Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development.
Foxg1 haploinsufficiency reduces the population of cortical intermediate progenitor cells: effect of increased p21 expression.
Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.
Effect of n-3 polyunsaturated fatty acids on Barrett's epithelium in the human lower esophagus.
Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.
Dearterialization of the liver causes intrahepatic cholestasis due to reduced bile transporter expression.
Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.
Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.
Prognostic significance of cell proliferation and apoptosis-regulating proteins in Epstein-Barr virus positive and negative pediatric Hodgkin lymphoma.
The efficacy and safety of topically applied indigo naturalis ointment in patients with plaque-type psoriasis.
The intermediate filament nestin is highly expressed in normal human podocytes and podocytes in glomerular disease.
The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.
Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.
Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of csk.
Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.
The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties.
SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.
Post-acute response of 9L gliosarcoma to Photofrin-mediated PDT in athymic nude mice.
Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets.
Objective risk definition for endometrial lesion spectrum: a diagnostic algorithm.
p63 Is essential for the proliferative potential of stem cells in stratified epithelia.
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract.
Snail silencing effectively suppresses tumour growth and invasiveness.
Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis.
Ferumoxtran-10 enhancement in orthotopic xenograft models of human brain tumors: an indirect marker of tumor proliferation?
Improved vascular engraftment and function of autotransplanted pancreatic islets as a result of partial pancreatectomy in the mouse and rat.
The properties of a mammary gland cancer stem cell.
Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647.
Microvascular proliferation in congenital vascular malformations of skin and soft tissue.
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence.
Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment.
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.
Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells.
Expression of glucose transporter protein-1 (Glut-1) in ocular surface squamous neoplasia.
Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models.
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.
Cellular responses to disruption of the permeability barrier in a three-dimensional organotypic epidermal model.
Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.
Lymphoma-like lesion of the uterine cervix: report of 12 cases of a rare entity.
Nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder: a case report and review of published reports.
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model.
Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.
Bile salt toxicity aggravates cold ischemic injury of bile ducts after liver transplantation in Mdr2+/- mice.
Effects of retrorsine on mouse hepatocyte proliferation after liver injury.
Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment.
Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord.
Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma.
Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma.
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
A three-dimensional model of differentiation of immortalized human bronchial epithelial cells.
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide.
Heparanase promotes growth, angiogenesis and survival of primary breast tumors.
Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex.
Resin tissue microarrays: a universal format for immunohistochemistry.
p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas.
The kd/kd mouse is a model of collapsing glomerulopathy.
Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer.
Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1.
Characterization and localization of side population cells in mouse skin.
A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model.
Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects.
Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model.
The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer.
Iazzolino G, Mendibil U, Arnaiz B, Ruiz-de-Angulo A, Azkargorta M, Uribe KB, Khatami N, Elortza F, Olalde B, Gomez-Vallejo V, Llop J, Abarrategi A
Frontiers in oncology 2022;12:956940
Frontiers in oncology 2022;12:956940
InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.
Magalhães AC, Ricardo S, Moreira AC, Nunes M, Tavares M, Pinto RJ, Gomes MS, Pereira L
Pathogens (Basel, Switzerland) 2022 Mar 3;11(3)
Pathogens (Basel, Switzerland) 2022 Mar 3;11(3)
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Katz LS, Brill G, Zhang P, Kumar A, Baumel-Alterzon S, Honig LB, Gómez-Banoy N, Karakose E, Tanase M, Doridot L, Alvarsson A, Davenport B, Wang P, Lambertini L, Stanley SA, Homann D, Stewart AF, Lo JC, Herman MA, Garcia-Ocaña A, Scott DK
Nature communications 2022 Jul 30;13(1):4423
Nature communications 2022 Jul 30;13(1):4423
Expression and Prognostic Value of Melanoma-Associated Antigen D2 in Gliomas.
Yan J, Li S, Lenahan C, Chen H, Wen J, Huang Q, Jiang Q, Guo F, Deng T, Mo L
Brain sciences 2022 Jul 26;12(8)
Brain sciences 2022 Jul 26;12(8)
Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types.
Shekhar K, Whitney IE, Butrus S, Peng YR, Sanes JR
eLife 2022 Feb 22;11
eLife 2022 Feb 22;11
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.
Olsen TK, Dyberg C, Embaie BT, Alchahin A, Milosevic J, Ding J, Otte J, Tümmler C, Hed Myrberg I, Westerhout EM, Koster J, Versteeg R, Ding HF, Kogner P, Johnsen JI, Sykes DB, Baryawno N
JCI insight 2022 Aug 9;7(17)
JCI insight 2022 Aug 9;7(17)
Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10.
Wang N, Li J, He J, Jing YG, Zhao WD, Yu WJ, Wang J
Journal of immunology research 2021;2021:8930813
Journal of immunology research 2021;2021:8930813
DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice.
Chen X, Huang NX, Cheng YJ, Cai QY, Tian YP, Chen XS, Xiao L
Frontiers in neuroscience 2021;15:659853
Frontiers in neuroscience 2021;15:659853
Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling.
Xu R, Zeng M, Wu Y, Wang S, Zhang B, Zhang J, Kan Y, Li B, Cao B, Zheng X, Feng W
OncoTargets and therapy 2021;14:3487-3501
OncoTargets and therapy 2021;14:3487-3501
The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition.
Xu X, Qiao D, Dong C, Mann M, Garofalo RP, Keles S, Brasier AR
Frontiers in immunology 2021;12:633654
Frontiers in immunology 2021;12:633654
Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes.
Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, Li CF, Wang LH, Chen HW, Yen Y, Ann DK, Wang HJ, Kung HJ
Theranostics 2021;11(15):7527-7545
Theranostics 2021;11(15):7527-7545
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Ranea-Robles P, Portman K, Bender A, Lee K, He JC, Mulholland DJ, Argmann C, Houten SM
Kidney360 2021 Sep;2(9):1441-1454
Kidney360 2021 Sep;2(9):1441-1454
Generation and functional characterization of murine mammary organoids.
Yip HYK, Papa A
STAR protocols 2021 Sep 17;2(3):100765
STAR protocols 2021 Sep 17;2(3):100765
Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes.
Bomer N, Pavez-Giani MG, Deiman FE, Linders AN, Hoes MF, Baierl CLJ, Oberdorf-Maass SU, de Boer RA, Silljé HHW, Berezikov E, Simonides WS, Westenbrink BD, van der Meer P
International journal of molecular sciences 2021 Nov 2;22(21)
International journal of molecular sciences 2021 Nov 2;22(21)
Sexual dimorphisms in brain gene expression in the growth-restricted guinea pig can be modulated with intra-placental therapy.
Wilson RL, Stephens KK, Lampe K, Jones HN
Pediatric research 2021 May;89(7):1673-1680
Pediatric research 2021 May;89(7):1673-1680
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisén J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundström E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I
Nature genetics 2021 May;53(5):694-706
Nature genetics 2021 May;53(5):694-706
Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.
Wang Y, Pandey RN, Roychoudhury K, Milewski D, Kalin TV, Szabo S, Pressey JG, Hegde RS
Molecular cancer therapeutics 2021 May;20(5):803-815
Molecular cancer therapeutics 2021 May;20(5):803-815
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, Venkataramani V, Michalke B, Romano E, Rillaerts K, Garg AD, Schepkens C, Bosisio FM, Wouters J, Oliveira AI, Vangheluwe P, Annaert W, Swinnen JV, Colet JM, van den Oord JJ, Fendt SM, Mazzone M, Agostinis P
The EMBO journal 2021 May 17;40(10):e106214
The EMBO journal 2021 May 17;40(10):e106214
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.
Parmar N, Burrows K, Vornewald PM, Lindholm HT, Zwiggelaar RT, Díez-Sánchez A, Martín-Alonso M, Fosslie M, Vallance BA, Dahl JA, Zaph C, Oudhoff MJ
PLoS pathogens 2021 Mar;17(3):e1009476
PLoS pathogens 2021 Mar;17(3):e1009476
Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC.
Zhang G, Yan G, Fu Z, Wu Y, Wu F, Zheng Z, Fang S, Gao Y, Bao X, Liu Y, Wang X, Zhu S
Cell death & disease 2021 Mar 4;12(3):247
Cell death & disease 2021 Mar 4;12(3):247
Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.
Zhang JQJ, Saravanabavan S, Rangan GK
Cells 2021 Mar 3;10(3)
Cells 2021 Mar 3;10(3)
Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo.
Thulin MH, Määttä J, Linder A, Sterbova S, Ohlsson C, Damber JE, Widmark A, Persson E
The Prostate 2021 Jun;81(8):452-462
The Prostate 2021 Jun;81(8):452-462
Insulin-like growth factor 1 promotes the extension of Tracheal Epithelium in an in Vitro Tracheal organ culture model.
Kishimoto I, Ohnishi H, Yamahara K, Nakagawa T, Yamashita M, Omori K, Yamamoto N
Auris, nasus, larynx 2021 Jun;48(3):441-450
Auris, nasus, larynx 2021 Jun;48(3):441-450
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.
Breunig M, Merkle J, Wagner M, Melzer MK, Barth TFE, Engleitner T, Krumm J, Wiedenmann S, Cohrs CM, Perkhofer L, Jain G, Krüger J, Hermann PC, Schmid M, Madácsy T, Varga Á, Griger J, Azoitei N, Müller M, Wessely O, Robey PG, Heller S, Dantes Z, Reichert M, Günes C, Bolenz C, Kuhn F, Maléth J, Speier S, Liebau S, Sipos B, Kuster B, Seufferlein T, Rad R, Meier M, Hohwieler M, Kleger A
Cell stem cell 2021 Jun 3;28(6):1105-1124.e19
Cell stem cell 2021 Jun 3;28(6):1105-1124.e19
Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction.
Low JL, Du W, Gocha T, Oguz G, Zhang X, Chen MW, Masirevic S, Yim DGR, Tan IBH, Ramasamy A, Fan H, DasGupta R
iScience 2021 Jun 25;24(6):102544
iScience 2021 Jun 25;24(6):102544
EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis.
Reehorst CM, Nightingale R, Luk IY, Jenkins L, Koentgen F, Williams DS, Darido C, Tan F, Anderton H, Chopin M, Schoffer K, Eissmann MF, Buchert M, Mouradov D, Sieber OM, Ernst M, Dhillon AS, Mariadason JM
Development (Cambridge, England) 2021 Jun 15;148(12)
Development (Cambridge, England) 2021 Jun 15;148(12)
STRADA-mutant human cortical organoids model megalencephaly and exhibit delayed neuronal differentiation.
Dang LT, Vaid S, Lin G, Swaminathan P, Safran J, Loughman A, Lee M, Glenn T, Majolo F, Crino PB, Parent JM
Developmental neurobiology 2021 Jul;81(5):696-709
Developmental neurobiology 2021 Jul;81(5):696-709
Rapid Prototyping of Multilayer Microphysiological Systems.
Hosic S, Bindas AJ, Puzan ML, Lake W, Soucy JR, Zhou F, Koppes RA, Breault DT, Murthy SK, Koppes AN
ACS biomaterials science & engineering 2021 Jul 12;7(7):2949-2963
ACS biomaterials science & engineering 2021 Jul 12;7(7):2949-2963
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Chen S, Chen X, Qiu J, Chen P, Han X, Wu Y, Zhuang J, Yang M, Wu C, Wu N, Yang Y, Ge J, Yu K, Zhuang J
Oncology reports 2021 Jan;45(1):278-290
Oncology reports 2021 Jan;45(1):278-290
A constant pool of Lgr5(+) intestinal stem cells is required for intestinal homeostasis.
Tan SH, Phuah P, Tan LT, Yada S, Goh J, Tomaz LB, Chua M, Wong E, Lee B, Barker N
Cell reports 2021 Jan 26;34(4):108633
Cell reports 2021 Jan 26;34(4):108633
TNFα promotes oral cancer growth, pain, and Schwann cell activation.
Salvo E, Tu NH, Scheff NN, Dubeykovskaya ZA, Chavan SA, Aouizerat BE, Ye Y
Scientific reports 2021 Jan 19;11(1):1840
Scientific reports 2021 Jan 19;11(1):1840
Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer.
Abdel Hamid HM, Darwish ZE, Elsheikh SM, Mourad GM, Donia HM, Afifi MM
BMC cancer 2021 Feb 17;21(1):170
BMC cancer 2021 Feb 17;21(1):170
Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis.
Yucer N, Ahdoot R, Workman MJ, Laperle AH, Recouvreux MS, Kurowski K, Naboulsi DJ, Liang V, Qu Y, Plummer JT, Gayther SA, Orsulic S, Karlan BY, Svendsen CN
Cell reports 2021 Dec 28;37(13):110146
Cell reports 2021 Dec 28;37(13):110146
Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance.
Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G
Science advances 2021 Apr;7(18)
Science advances 2021 Apr;7(18)
Immunohistochemical evaluation of hepatic progenitor cells in different types of feline liver diseases.
Abou Monsef Y, Kutsal O
The Journal of veterinary medical science 2021 Apr 9;83(4):613-621
The Journal of veterinary medical science 2021 Apr 9;83(4):613-621
miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis.
Zhang J, Han L, Yu J, Li H, Li Q
Aging 2021 Apr 4;13(7):10431-10449
Aging 2021 Apr 4;13(7):10431-10449
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Gangoso E, Southgate B, Bradley L, Rus S, Galvez-Cancino F, McGivern N, Güç E, Kapourani CA, Byron A, Ferguson KM, Alfazema N, Morrison G, Grant V, Blin C, Sou I, Marques-Torrejon MA, Conde L, Parrinello S, Herrero J, Beck S, Brandner S, Brennan PM, Bertone P, Pollard JW, Quezada SA, Sproul D, Frame MC, Serrels A, Pollard SM
Cell 2021 Apr 29;184(9):2454-2470.e26
Cell 2021 Apr 29;184(9):2454-2470.e26
Histological and Immunohistochemical Characterization of Vomeronasal Organ Aging in Mice.
Mechin V, Pageat P, Teruel E, Asproni P
Animals : an open access journal from MDPI 2021 Apr 22;11(5)
Animals : an open access journal from MDPI 2021 Apr 22;11(5)
Evidence and manipulation of O-GlcNAcylation in granulosa cells of bovine antral follicles†.
Maucieri AM, Townson DH
Biology of reproduction 2021 Apr 1;104(4):914-923
Biology of reproduction 2021 Apr 1;104(4):914-923
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation.
Ostrop J, Zwiggelaar RT, Terndrup Pedersen M, Gerbe F, Bösl K, Lindholm HT, Díez-Sánchez A, Parmar N, Radetzki S, von Kries JP, Jay P, Jensen KB, Arrowsmith C, Oudhoff MJ
Frontiers in cell and developmental biology 2020;8:618552
Frontiers in cell and developmental biology 2020;8:618552
IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.
Gasilina A, Premnauth G, Gurjar P, Biesiada J, Hegde S, Milewski D, Ma G, Kalin TV, Merino E, Meller J, Seibel W, Cancelas JA, Vinnedge LP, Nassar NN
PloS one 2020;15(3):e0229801
PloS one 2020;15(3):e0229801
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.
Zwiggelaar RT, Lindholm HT, Fosslie M, Terndrup Pedersen M, Ohta Y, Díez-Sánchez A, Martín-Alonso M, Ostrop J, Matano M, Parmar N, Kvaløy E, Spanjers RR, Nazmi K, Rye M, Drabløs F, Arrowsmith C, Arne Dahl J, Jensen KB, Sato T, Oudhoff MJ
Science advances 2020 Sep;6(37)
Science advances 2020 Sep;6(37)
Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis.
Shue YT, Lee KT, Walters BW, Ong HB, Silvaraju S, Lam WJ, Lim CY
Epigenetics 2020 Sep;15(9):932-948
Epigenetics 2020 Sep;15(9):932-948
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.
Recouvreux MV, Moldenhauer MR, Galenkamp KMO, Jung M, James B, Zhang Y, Lowy A, Bagchi A, Commisso C
The Journal of experimental medicine 2020 Sep 7;217(9)
The Journal of experimental medicine 2020 Sep 7;217(9)
High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.
Hases L, Archer A, Indukuri R, Birgersson M, Savva C, Korach-André M, Williams C
Scientific reports 2020 Sep 30;10(1):16160
Scientific reports 2020 Sep 30;10(1):16160
RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5.
Cayre S, Faraldo MM, Bardin S, Miserey-Lenkei S, Deugnier MA, Goud B
Development (Cambridge, England) 2020 Oct 8;147(19)
Development (Cambridge, England) 2020 Oct 8;147(19)
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.
Yao CD, Haensel D, Gaddam S, Patel T, Atwood SX, Sarin KY, Whitson RJ, McKellar S, Shankar G, Aasi S, Rieger K, Oro AE
Nature communications 2020 Oct 8;11(1):5079
Nature communications 2020 Oct 8;11(1):5079
Secondary ossification center induces and protects growth plate structure.
Xie M, Gol'din P, Herdina AN, Estefa J, Medvedeva EV, Li L, Newton PT, Kotova S, Shavkuta B, Saxena A, Shumate LT, Metscher BD, Großschmidt K, Nishimori S, Akovantseva A, Usanova AP, Kurenkova AD, Kumar A, Arregui IL, Tafforeau P, Fried K, Carlström M, Simon A, Gasser C, Kronenberg HM, Bastepe M, Cooper KL, Timashev P, Sanchez S, Adameyko I, Eriksson A, Chagin AS
eLife 2020 Oct 16;9
eLife 2020 Oct 16;9
Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.
Lan C, Cao N, Chen C, Qu S, Fan C, Luo H, Zeng A, Yu C, Xue Y, Ren H, Li L, Wang H, Jose PA, Xu Z, Zeng C
Cell proliferation 2020 Nov;53(11):e12910
Cell proliferation 2020 Nov;53(11):e12910
Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors.
Wang Y, Wozniak A, Wellens J, Gebreyohannes YK, Guillén MJ, Avilés PM, Debiec-Rychter M, Sciot R, Schöffski P
Translational oncology 2020 Nov;13(11):100832
Translational oncology 2020 Nov;13(11):100832
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice.
Landerer S, Kalthoff S, Paulusch S, Strassburg CP
Cancer science 2020 Nov;111(11):4266-4275
Cancer science 2020 Nov;111(11):4266-4275
Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk.
Konger RL, Ren L, Sahu RP, Derr-Yellin E, Kim YL
Scientific reports 2020 Nov 5;10(1):19200
Scientific reports 2020 Nov 5;10(1):19200
The secretome of human dental pulp stem cells protects myoblasts from hypoxia‑induced injury via the Wnt/β‑catenin pathway.
Zhang W, Yu L, Han X, Pan J, Deng J, Zhu L, Lu Y, Huang W, Liu S, Li Q, Liu Y
International journal of molecular medicine 2020 May;45(5):1501-1513
International journal of molecular medicine 2020 May;45(5):1501-1513
Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis.
Na HJ, Akan I, Abramowitz LK, Hanover JA
Cell reports 2020 May 12;31(6):107632
Cell reports 2020 May 12;31(6):107632
Silencing of long‑chain non‑coding RNA GAS5 in osteoarthritic chondrocytes is mediated by targeting the miR‑34a/Bcl‑2 axis.
Ji Q, Qiao X, Liu Y, Wang D, Yan J
Molecular medicine reports 2020 Mar;21(3):1310-1319
Molecular medicine reports 2020 Mar;21(3):1310-1319
Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.
Liu P, Liang B, Liu M, Lebbink JHG, Li S, Qian M, Lavrijsen M, Peppelenbosch MP, Chen X, Smits R
Gastroenterology 2020 Mar;158(4):1029-1043.e10
Gastroenterology 2020 Mar;158(4):1029-1043.e10
Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice.
Barca-Mayo O, Boender AJ, Armirotti A, De Pietri Tonelli D
Glia 2020 Jun;68(6):1131-1147
Glia 2020 Jun;68(6):1131-1147
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease.
Yazdankhah M, Shang P, Ghosh S, Bhutto IA, Stepicheva N, Grebe R, Hose S, Weiss J, Luo T, Mishra S, Riazuddin SA, Ghosh A, Handa JT, Lutty GA, Zigler JS Jr, Sinha D
Autophagy 2020 Jun;16(6):1130-1142
Autophagy 2020 Jun;16(6):1130-1142
Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.
Uroda T, Chillón I, Annibale P, Teulon JM, Pessey O, Karuppasamy M, Pellequer JL, Marcia M
Nature protocols 2020 Jun;15(6):2107-2139
Nature protocols 2020 Jun;15(6):2107-2139
Long-term PM(2.5) exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis.
Chao X, Yi L, Lan LL, Wei HY, Wei D
Aging 2020 Jun 18;12(12):11579-11602
Aging 2020 Jun 18;12(12):11579-11602
Optic vesicle morphogenesis requires primary cilia.
Fiore L, Takata N, Acosta S, Ma W, Pandit T, Oxendine M, Oliver G
Developmental biology 2020 Jun 15;462(2):119-128
Developmental biology 2020 Jun 15;462(2):119-128
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
Zhou Y, Xu M, Liu P, Liang B, Qian M, Wang H, Song X, Nyshadham P, Che L, Calvisi DF, Li F, Lin S, Chen X
The American journal of pathology 2020 Jul;190(7):1414-1426
The American journal of pathology 2020 Jul;190(7):1414-1426
Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression.
Sawyer BT, Qamar L, Yamamoto TM, McMellen A, Watson ZL, Richer JK, Behbakht K, Schlaepfer IR, Bitler BG
Molecular cancer research : MCR 2020 Jul;18(7):1088-1098
Molecular cancer research : MCR 2020 Jul;18(7):1088-1098
Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.
Kogot-Levin A, Hinden L, Riahi Y, Israeli T, Tirosh B, Cerasi E, Mizrachi EB, Tam J, Mosenzon O, Leibowitz G
Cell reports 2020 Jul 28;32(4):107954
Cell reports 2020 Jul 28;32(4):107954
The sialyltransferase ST6GAL1 protects against radiation-induced gastrointestinal damage.
Punch PR, Irons EE, Manhardt CT, Marathe H, Lau JTY
Glycobiology 2020 Jul 20;30(7):446-453
Glycobiology 2020 Jul 20;30(7):446-453
Novel CD11b(+)Gr-1(+)Sca-1(+) myeloid cells drive mortality in bacterial infection.
Park MY, Kim HS, Lee HY, Zabel BA, Bae YS
Science advances 2020 Jan;6(4):eaax8820
Science advances 2020 Jan;6(4):eaax8820
An intrinsic role of IL-33 in T(reg) cell-mediated tumor immunoevasion.
Hatzioannou A, Banos A, Sakelaropoulos T, Fedonidis C, Vidali MS, Köhne M, Händler K, Boon L, Henriques A, Koliaraki V, Georgiadis P, Zoidakis J, Termentzi A, Beyer M, Chavakis T, Boumpas D, Tsirigos A, Verginis P
Nature immunology 2020 Jan;21(1):75-85
Nature immunology 2020 Jan;21(1):75-85
Loss of Setd4 delays radiation-induced thymic lymphoma in mice.
Feng X, Lu H, Yue J, Schneider N, Liu J, Denzin LK, Chan CS, De S, Shen Z
DNA repair 2020 Feb;86:102754
DNA repair 2020 Feb;86:102754
AQP5 enriches for stem cells and cancer origins in the distal stomach.
Tan SH, Swathi Y, Tan S, Goh J, Seishima R, Murakami K, Oshima M, Tsuji T, Phuah P, Tan LT, Wong E, Fatehullah A, Sheng T, Ho SWT, Grabsch HI, Srivastava S, Teh M, Denil SLIJ, Mustafah S, Tan P, Shabbir A, So J, Yeoh KG, Barker N
Nature 2020 Feb;578(7795):437-443
Nature 2020 Feb;578(7795):437-443
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Wang P, Song X, Cao D, Cui K, Wang J, Utpatel K, Shang R, Wang H, Che L, Evert M, Zhao K, Calvisi DF, Chen X
Cell death & disease 2020 Feb 4;11(2):91
Cell death & disease 2020 Feb 4;11(2):91
Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
Kalucka J, de Rooij LPMH, Goveia J, Rohlenova K, Dumas SJ, Meta E, Conchinha NV, Taverna F, Teuwen LA, Veys K, García-Caballero M, Khan S, Geldhof V, Sokol L, Chen R, Treps L, Borri M, de Zeeuw P, Dubois C, Karakach TK, Falkenberg KD, Parys M, Yin X, Vinckier S, Du Y, Fenton RA, Schoonjans L, Dewerchin M, Eelen G, Thienpont B, Lin L, Bolund L, Li X, Luo Y, Carmeliet P
Cell 2020 Feb 20;180(4):764-779.e20
Cell 2020 Feb 20;180(4):764-779.e20
Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Di Magno L, Manni S, Di Pastena F, Coni S, Macone A, Cairoli S, Sambucci M, Infante P, Moretti M, Petroni M, Nicoletti C, Capalbo C, De Smaele E, Di Marcotullio L, Giannini G, Battistini L, Goffredo BM, Iorio E, Agostinelli E, Maroder M, Canettieri G
Cell reports 2020 Feb 11;30(6):1735-1752.e7
Cell reports 2020 Feb 11;30(6):1735-1752.e7
Immune Modulation to Improve Survival of Viral Pneumonia in Mice.
Wali S, Flores JR, Jaramillo AM, Goldblatt DL, Pantaleón García J, Tuvim MJ, Dickey BF, Evans SE
American journal of respiratory cell and molecular biology 2020 Dec;63(6):758-766
American journal of respiratory cell and molecular biology 2020 Dec;63(6):758-766
Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro.
Elena Sima L, Bonciu A, Baciu M, Anghel I, Dumitrescu LN, Rusen L, Dinca V
Nanomaterials (Basel, Switzerland) 2020 Dec 9;10(12)
Nanomaterials (Basel, Switzerland) 2020 Dec 9;10(12)
Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice.
Thomas MJ, Major E, Benedek A, Horváth I, Máthé D, Bergmann R, Szász AM, Krenács T, Benyó Z
Cancers 2020 Dec 21;12(12)
Cancers 2020 Dec 21;12(12)
Long non-coding RNA RFPL3S is a novel prognostic biomarker in lung cancer.
Liu Z, Ning Z, Lu H, Cao T, Zhou F, Ye X, Chen C
Oncology letters 2020 Aug;20(2):1270-1280
Oncology letters 2020 Aug;20(2):1270-1280
Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models.
Krenacs T, Meggyeshazi N, Forika G, Kiss E, Hamar P, Szekely T, Vancsik T
International journal of molecular sciences 2020 Aug 29;21(17)
International journal of molecular sciences 2020 Aug 29;21(17)
Positive Effects of Preventive Nutrition Supplement on Anticancer Radiotherapy in Lung Cancer Bearing Mice.
Liu YM, Wu TH, Chiu YH, Wang H, Li TL, Hsia S, Chan YL, Wu CJ
Cancers 2020 Aug 28;12(9)
Cancers 2020 Aug 28;12(9)
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Sodir NM, Kortlever RM, Barthet VJA, Campos T, Pellegrinet L, Kupczak S, Anastasiou P, Swigart LB, Soucek L, Arends MJ, Littlewood TD, Evan GI
Cancer discovery 2020 Apr;10(4):588-607
Cancer discovery 2020 Apr;10(4):588-607
Yolk-sac-derived macrophages progressively expand in the mouse kidney with age.
Ide S, Yahara Y, Kobayashi Y, Strausser SA, Ide K, Watwe A, Xu-Vanpala S, Privratsky JR, Crowley SD, Shinohara ML, Alman BA, Souma T
eLife 2020 Apr 17;9
eLife 2020 Apr 17;9
A Novel Approach to Deliver Therapeutic Extracellular Vesicles Directly into the Mouse Kidney via Its Arterial Blood Supply.
Ullah M, Liu DD, Rai S, Razavi M, Choi J, Wang J, Concepcion W, Thakor AS
Cells 2020 Apr 10;9(4)
Cells 2020 Apr 10;9(4)
Preclinical efficacy of hK2 targeted [(177)Lu]hu11B6 for prostate cancer theranostics.
Timmermand OV, Elgqvist J, Beattie KA, Örbom A, Larsson E, Eriksson SE, Thorek DLJ, Beattie BJ, Tran TA, Ulmert D, Strand SE
Theranostics 2019;9(8):2129-2142
Theranostics 2019;9(8):2129-2142
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Sang Y, Li Y, Zhang Y, Alvarez AA, Yu B, Zhang W, Hu B, Cheng SY, Feng H
Nature communications 2019 Sep 5;10(1):4013
Nature communications 2019 Sep 5;10(1):4013
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, Berry KP, Pribnow A, Smith SM, Fuller C, Jones BV, Fouladi M, Drissi R, Yang ZJ, Gustafson WC, Remke M, Pomeroy SL, Girard EJ, Olson JM, Morrissy AS, Vladoiu MC, Zhang J, Tian W, Xin M, Taylor MD, Potter SS, Roussel MF, Weiss WA, Lu QR
Cancer cell 2019 Sep 16;36(3):302-318.e7
Cancer cell 2019 Sep 16;36(3):302-318.e7
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.
Mondragón L, Mhaidly R, De Donatis GM, Tosolini M, Dao P, Martin AR, Pons C, Chiche J, Jacquin M, Imbert V, Proïcs E, Boyer L, Doye A, Luciano F, Neels JG, Coutant F, Fabien N, Sormani L, Rubio-Patiño C, Bossowski JP, Muller F, Marchetti S, Villa E, Peyron JF, Gaulard P, Lemonnier F, Asnafi V, Genestier L, Benhida R, Fournié JJ, Passeron T, Ricci JE, Verhoeyen E
Cancer cell 2019 Sep 16;36(3):268-287.e10
Cancer cell 2019 Sep 16;36(3):268-287.e10
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Wang Y, Pandey RN, York AJ, Mallela J, Nichols WC, Hu YC, Molkentin JD, Wikenheiser-Brokamp KA, Hegde RS
Nature communications 2019 Sep 12;10(1):4143
Nature communications 2019 Sep 12;10(1):4143
Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.
Thomson BR, Carota IA, Souma T, Soman S, Vestweber D, Quaggin SE
eLife 2019 Oct 17;8
eLife 2019 Oct 17;8
RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R
Cell death and differentiation 2019 May;26(5):877-889
Cell death and differentiation 2019 May;26(5):877-889
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X
The American journal of pathology 2019 May;189(5):1077-1090
The American journal of pathology 2019 May;189(5):1077-1090
Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.
Mihara H, Kugawa M, Sayo K, Tao F, Shinohara M, Nishikawa M, Sakai Y, Akama T, Kojima N
Cells 2019 May 31;8(6)
Cells 2019 May 31;8(6)
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.
Rajakulendran N, Rowland KJ, Selvadurai HJ, Ahmadi M, Park NI, Naumenko S, Dolma S, Ward RJ, So M, Lee L, MacLeod G, Pasiliao C, Brandon C, Clarke ID, Cusimano MD, Bernstein M, Batada N, Angers S, Dirks PB
Genes & development 2019 May 1;33(9-10):498-510
Genes & development 2019 May 1;33(9-10):498-510
Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.
Linder B, Weirauch U, Ewe A, Uhmann A, Seifert V, Mittelbronn M, Harter PN, Aigner A, Kögel D
Cancers 2019 Mar 8;11(3)
Cancers 2019 Mar 8;11(3)
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.
Kennedy SP, Han JZR, Portman N, Nobis M, Hastings JF, Murphy KJ, Latham SL, Cadell AL, Miladinovic D, Marriott GR, O'Donnell YEI, Shearer RF, Williams JT, Munoz AG, Cox TR, Watkins DN, Saunders DN, Timpson P, Lim E, Kolch W, Croucher DR
Breast cancer research : BCR 2019 Mar 21;21(1):43
Breast cancer research : BCR 2019 Mar 21;21(1):43
Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea.
Peters MF, Landry T, Pin C, Maratea K, Dick C, Wagoner MP, Choy AL, Barthlow H, Snow D, Stevens Z, Armento A, Scott CW, Ayehunie S
Toxicological sciences : an official journal of the Society of Toxicology 2019 Mar 1;168(1):3-17
Toxicological sciences : an official journal of the Society of Toxicology 2019 Mar 1;168(1):3-17
Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification.
Czarnewski P, Parigi SM, Sorini C, Diaz OE, Das S, Gagliani N, Villablanca EJ
Nature communications 2019 Jun 28;10(1):2892
Nature communications 2019 Jun 28;10(1):2892
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L
Nature communications 2019 Jul 24;10(1):3304
Nature communications 2019 Jul 24;10(1):3304
Developmental changes in interkinetic nuclear migration dynamics with respect to cell-cycle progression in the mouse cerebral cortex ventricular zone.
Fousse J, Gautier E, Patti D, Dehay C
The Journal of comparative neurology 2019 Jul 1;527(10):1545-1557
The Journal of comparative neurology 2019 Jul 1;527(10):1545-1557
Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
Román M, López I, Guruceaga E, Baraibar I, Ecay M, Collantes M, Nadal E, Vallejo A, Cadenas S, Miguel ME, Jang JH, Martin-Uriz PS, Castro-Labrador L, Vilas-Zornoza A, Lara-Astiaso D, Ponz-Sarvise M, Rolfo C, Santos ES, Raez LE, Taverna S, Behrens C, Weder W, Wistuba II, Vicent S, Gil-Bazo I
Cancer research 2019 Feb 1;79(3):625-638
Cancer research 2019 Feb 1;79(3):625-638
Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells.
Cook L, Stahl M, Han X, Nazli A, MacDonald KN, Wong MQ, Tsai K, Dizzell S, Jacobson K, Bressler B, Kaushic C, Vallance BA, Steiner TS, Levings MK
Gastroenterology 2019 Dec;157(6):1584-1598
Gastroenterology 2019 Dec;157(6):1584-1598
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Petroni M, Sahùn Roncero M, Ramponi V, Fabretti F, Nicolis Di Robilant V, Moretti M, Alfano V, Corsi A, De Panfilis S, Giubettini M, Di Giulio S, Capalbo C, Belardinilli F, Coppa A, Sardina F, Colicchia V, Pedretti F, Infante P, Cardinali B, Tessitore A, Canettieri G, De Smaele E, Giannini G
Scientific reports 2019 Dec 23;9(1):19623
Scientific reports 2019 Dec 23;9(1):19623
Combination of laser and human adipose-derived stem cells in repair of rabbit anal sphincter injury: a new therapeutic approach.
Sarveazad A, Babahajian A, Yari A, Rayner CK, Mokhtare M, Babaei-Ghazani A, Agah S, Mahjoubi B, Shamseddin J, Yousefifard M
Stem cell research & therapy 2019 Dec 2;10(1):367
Stem cell research & therapy 2019 Dec 2;10(1):367
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
Huang CM, Huang CS, Hsu TN, Huang MS, Fong IH, Lee WH, Liu SC
Cells 2019 Dec 18;9(1)
Cells 2019 Dec 18;9(1)
Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis.
Li Y, Xu Y, Jadhav K, Zhu Y, Yin L, Zhang Y
Arteriosclerosis, thrombosis, and vascular biology 2019 Aug;39(8):1574-1587
Arteriosclerosis, thrombosis, and vascular biology 2019 Aug;39(8):1574-1587
The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats.
Maejima Y, Yokota S, Horita S, Shimomura K
Scientific reports 2019 Aug 14;9(1):11848
Scientific reports 2019 Aug 14;9(1):11848
Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice.
Rogers RG, Fournier M, Sanchez L, Ibrahim AG, Aminzadeh MA, Lewis MI, Marbán E
JCI insight 2019 Apr 4;4(7)
JCI insight 2019 Apr 4;4(7)
Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation.
Christodoulou-Vafeiadou E, Ioakeimidis F, Andreadou M, Giagkas G, Stamatakis G, Reczko M, Samiotaki M, Papanastasiou AD, Karakasiliotis I, Kontoyiannis DL
Frontiers in immunology 2018;9:2732
Frontiers in immunology 2018;9:2732
Development of a murine intravesical orthotopic human bladder cancer (mio-hBC) model.
Raven PA, D'Costa NM, Moskalev I, Tan Z, Frees S, Chavez-Munoz C, So AI
American journal of clinical and experimental urology 2018;6(6):245-259
American journal of clinical and experimental urology 2018;6(6):245-259
Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli.
Ye W, Takabayashi H, Yang Y, Mao M, Hibdon ES, Samuelson LC, Eaton KA, Todisco A
Cellular and molecular gastroenterology and hepatology 2018;5(4):523-538
Cellular and molecular gastroenterology and hepatology 2018;5(4):523-538
UXT is required for spermatogenesis in mice.
Schafler ED, Thomas PA, Ha S, Wang Y, Bermudez-Hernandez K, Tang Z, Fenyö D, Vigodner M, Logan SK
PloS one 2018;13(4):e0195747
PloS one 2018;13(4):e0195747
Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.
Xiao D, Jin K, Xiang M
Frontiers in molecular neuroscience 2018;11:271
Frontiers in molecular neuroscience 2018;11:271
Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators.
Ahmad M, Kroll T, Jakob J, Rauch A, Ploubidou A, Tuckermann J
Scientific reports 2018 Sep 19;8(1):14045
Scientific reports 2018 Sep 19;8(1):14045
The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Gyllborg D, Ahmed M, Toledo EM, Theofilopoulos S, Yang S, Ffrench-Constant C, Arenas E
Stem cell reports 2018 Sep 11;11(3):651-664
Stem cell reports 2018 Sep 11;11(3):651-664
Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression.
Linder A, Hagberg Thulin M, Damber JE, Welén K
Scientific reports 2018 Nov 22;8(1):17259
Scientific reports 2018 Nov 22;8(1):17259
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB
Cancer cell 2018 May 14;33(5):905-921.e5
Cancer cell 2018 May 14;33(5):905-921.e5
WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.
Abu-Remaileh M, Khalaileh A, Pikarsky E, Aqeilan RI
Cell death & disease 2018 May 1;9(5):511
Cell death & disease 2018 May 1;9(5):511
Luteinizing hormone compromises the in vivo anti-tumor effect of cisplatin on human epithelial ovarian cancer cells.
Huang Y, Zhou Y, Xia L, Tang J, Wen H, Zhang M
Oncology letters 2018 Mar;15(3):3141-3146
Oncology letters 2018 Mar;15(3):3141-3146
Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.
Newton PT, Xie M, Medvedeva EV, Sävendahl L, Chagin AS
Bone reports 2018 Jun;8:64-71
Bone reports 2018 Jun;8:64-71
Therapeutic Targeting of Sunitinib-Induced AR Phosphorylation in Renal Cell Carcinoma.
Adelaiye-Ogala R, Damayanti NP, Orillion AR, Arisa S, Chintala S, Titus MA, Kao C, Pili R
Cancer research 2018 Jun 1;78(11):2886-2896
Cancer research 2018 Jun 1;78(11):2886-2896
Low-dose statin treatment increases prostate cancer aggressiveness.
Caro-Maldonado A, Camacho L, Zabala-Letona A, Torrano V, Fernández-Ruiz S, Zamacola-Bascaran K, Arreal L, Valcárcel-Jiménez L, Martín-Martín N, Flores JM, Cortazar AR, Zúñiga-García P, Arruabarrena-Aristorena A, Guillaumond F, Cabrera D, Falcón-Perez JM, Aransay AM, Gomez-Muñoz A, Olivan M, Morote J, Carracedo A
Oncotarget 2018 Jan 5;9(2):1494-1504
Oncotarget 2018 Jan 5;9(2):1494-1504
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.
Tögel L, Nightingale R, Wu R, Chüeh AC, Al-Obaidi S, Luk I, Dávalos-Salas M, Chionh F, Murone C, Buchanan DD, Chatterton Z, Sieber OM, Arango D, Tebbutt NC, Williams D, Dhillon AS, Mariadason JM
Scientific reports 2018 Jan 29;8(1):1767
Scientific reports 2018 Jan 29;8(1):1767
HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.
Efimova EV, Ricco N, Labay E, Mauceri HJ, Flor AC, Ramamurthy A, Sutton HG, Weichselbaum RR, Kron SJ
Molecular cancer therapeutics 2018 Feb;17(2):407-418
Molecular cancer therapeutics 2018 Feb;17(2):407-418
A new genetically engineered mouse model of choroid plexus carcinoma.
El Nagar S, Zindy F, Moens C, Martin L, Plassard D, Roussel MF, Lamonerie T, Billon N
Biochemical and biophysical research communications 2018 Feb 5;496(2):568-574
Biochemical and biophysical research communications 2018 Feb 5;496(2):568-574
Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.
Sun X, Gupta K, Wu B, Zhang D, Yuan B, Zhang X, Chiang HC, Zhang C, Curiel TJ, Bendeck MP, Hursting S, Hu Y, Li R
The Journal of biological chemistry 2018 Feb 23;293(8):2841-2849
The Journal of biological chemistry 2018 Feb 23;293(8):2841-2849
Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance.
Jain RW, Parham KA, Tesfagiorgis Y, Craig HC, Romanchik E, Kerfoot SM
Cell reports 2018 Dec 18;25(12):3342-3355.e5
Cell reports 2018 Dec 18;25(12):3342-3355.e5
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
Lian YF, Huang YL, Wang JL, Deng MH, Xia TL, Zeng MS, Chen MS, Wang HB, Huang YH
Aging 2018 Aug 9;10(8):1884-1901
Aging 2018 Aug 9;10(8):1884-1901
JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.
Singh K, Camera E, Krug L, Basu A, Pandey RK, Munir S, Wlaschek M, Kochanek S, Schorpp-Kistner M, Picardo M, Angel P, Niemann C, Maity P, Scharffetter-Kochanek K
Nature communications 2018 Aug 24;9(1):3425
Nature communications 2018 Aug 24;9(1):3425
Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice.
Mikyskova R, Indrova M, Stepanek I, Kanchev I, Bieblova J, Vosahlikova S, Moserova I, Truxova I, Fucikova J, Bartunkova J, Spisek R, Sedlacek R, Reinis M
Oncoimmunology 2017;6(12):e1362528
Oncoimmunology 2017;6(12):e1362528
Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model.
Malchenko S, Sredni ST, Bi Y, Margaryan NV, Boyineni J, Mohanam I, Tomita T, Davuluri RV, Soares MB
PloS one 2017;12(3):e0173106
PloS one 2017;12(3):e0173106
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
He W, Roh E, Yao K, Liu K, Meng X, Liu F, Wang P, Bode AM, Dong Z
NPJ precision oncology 2017;1(1):13
NPJ precision oncology 2017;1(1):13
Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.
Anderton H, Rickard JA, Varigos GA, Lalaoui N, Silke J
The Journal of investigative dermatology 2017 Nov;137(11):2371-2379
The Journal of investigative dermatology 2017 Nov;137(11):2371-2379
Kctd13 deletion reduces synaptic transmission via increased RhoA.
Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-García IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM
Nature 2017 Nov 9;551(7679):227-231
Nature 2017 Nov 9;551(7679):227-231
Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ
Nucleic acids research 2017 Nov 2;45(19):11174-11192
Nucleic acids research 2017 Nov 2;45(19):11174-11192
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni S, Mancuso AB, Di Magno L, Sdruscia G, Manni S, Serrao SM, Rotili D, Spiombi E, Bufalieri F, Petroni M, Kusio-Kobialka M, De Smaele E, Ferretti E, Capalbo C, Mai A, Niewiadomski P, Screpanti I, Di Marcotullio L, Canettieri G
Scientific reports 2017 Mar 9;7:44079
Scientific reports 2017 Mar 9;7:44079
Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.
Sgourdou P, Mishra-Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, Ishigame K, Giannikou K, Quon JL, Sestan N, Caglayan AO, Gunel M, Louvi A
Scientific reports 2017 Mar 8;7:43708
Scientific reports 2017 Mar 8;7:43708
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Che L, Pilo MG, Cigliano A, Latte G, Simile MM, Ribback S, Dombrowski F, Evert M, Chen X, Calvisi DF
Cell cycle (Georgetown, Tex.) 2017 Mar 19;16(6):499-507
Cell cycle (Georgetown, Tex.) 2017 Mar 19;16(6):499-507
Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response.
Savarin M, Kamensek U, Cemazar M, Heller R, Sersa G
Radiology and oncology 2017 Mar 1;51(1):30-39
Radiology and oncology 2017 Mar 1;51(1):30-39
Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.
Xia H, Gilbertsen A, Herrera J, Racila E, Smith K, Peterson M, Griffin T, Benyumov A, Yang L, Bitterman PB, Henke CA
The Journal of clinical investigation 2017 Jun 30;127(7):2586-2597
The Journal of clinical investigation 2017 Jun 30;127(7):2586-2597
Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.
Zhang X, Chiang HC, Wang Y, Zhang C, Smith S, Zhao X, Nair SJ, Michalek J, Jatoi I, Lautner M, Oliver B, Wang H, Petit A, Soler T, Brunet J, Mateo F, Angel Pujana M, Poggi E, Chaldekas K, Isaacs C, Peshkin BN, Ochoa O, Chedin F, Theoharis C, Sun LZ, Curiel TJ, Elledge R, Jin VX, Hu Y, Li R
Nature communications 2017 Jun 26;8:15908
Nature communications 2017 Jun 26;8:15908
Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.
Loveridge CJ, Mui EJ, Patel R, Tan EH, Ahmad I, Welsh M, Galbraith J, Hedley A, Nixon C, Blyth K, Sansom O, Leung HY
Cancer research 2017 Jun 15;77(12):3158-3168
Cancer research 2017 Jun 15;77(12):3158-3168
In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents.
Cui MT, Jiang L, Goto M, Hsu PL, Li L, Zhang Q, Wei L, Yuan SJ, Hamel E, Morris-Natschke SL, Lee KH, Xie L
Journal of medicinal chemistry 2017 Jul 13;60(13):5586-5598
Journal of medicinal chemistry 2017 Jul 13;60(13):5586-5598
GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis.
Wu X, Wang H, Lian Y, Chen L, Gu L, Wang J, Huang Y, Deng M, Gao Z, Huang Y
Scientific reports 2017 Jul 11;7(1):5129
Scientific reports 2017 Jul 11;7(1):5129
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
Lázaro S, Pérez-Crespo M, Enguita AB, Hernández P, Martínez-Palacio J, Oteo M, Sage J, Paramio JM, Santos M
Oncotarget 2017 Jan 17;8(3):4373-4386
Oncotarget 2017 Jan 17;8(3):4373-4386
VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.
Comunanza V, Corà D, Orso F, Consonni FM, Middonti E, Di Nicolantonio F, Buzdin A, Sica A, Medico E, Sangiolo D, Taverna D, Bussolino F
EMBO molecular medicine 2017 Feb;9(2):219-237
EMBO molecular medicine 2017 Feb;9(2):219-237
Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.
de Jong RJ, Paulin N, Lemnitzer P, Viola JR, Winter C, Ferraro B, Grommes J, Weber C, Reutelingsperger C, Drechsler M, Soehnlein O
Arteriosclerosis, thrombosis, and vascular biology 2017 Feb;37(2):312-315
Arteriosclerosis, thrombosis, and vascular biology 2017 Feb;37(2):312-315
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.
Hopkinson BM, Klitgaard MC, Petersen OW, Villadsen R, Rønnov-Jessen L, Kim J
Oncotarget 2017 Feb 7;8(6):10580-10593
Oncotarget 2017 Feb 7;8(6):10580-10593
Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P, Xu RH, Chiao PJ
Nature communications 2017 Feb 24;8:14437
Nature communications 2017 Feb 24;8:14437
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.
Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Valencia K, Arricibita A, Gwinn D, Sayles LC, Chuang CH, Guembe L, Bailey P, Chang DK, Biankin A, Ponz-Sarvise M, Andersen JB, Khatri P, Bozec A, Sweet-Cordero EA, Sage J, Lecanda F, Vicent S
Nature communications 2017 Feb 21;8:14294
Nature communications 2017 Feb 21;8:14294
Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.
Li J, Lu D, Liu H, Williams BO, Overbeek PA, Lee B, Zheng L, Yang T
Human molecular genetics 2017 Aug 1;26(15):2949-2960
Human molecular genetics 2017 Aug 1;26(15):2949-2960
FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI
Molecular and cellular biology 2017 Apr 15;37(8)
Molecular and cellular biology 2017 Apr 15;37(8)
miR-342-5p Regulates Neural Stem Cell Proliferation and Differentiation Downstream to Notch Signaling in Mice.
Gao F, Zhang YF, Zhang ZP, Fu LA, Cao XL, Zhang YZ, Guo CJ, Yan XC, Yang QC, Hu YY, Zhao XH, Wang YZ, Wu SX, Ju G, Zheng MH, Han H
Stem cell reports 2017 Apr 11;8(4):1032-1045
Stem cell reports 2017 Apr 11;8(4):1032-1045
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.
Dubail J, Vasudevan D, Wang LW, Earp SE, Jenkins MW, Haltiwanger RS, Apte SS
Scientific reports 2016 Sep 30;6:33974
Scientific reports 2016 Sep 30;6:33974
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A
Cell 2016 Nov 17;167(5):1264-1280.e18
Cell 2016 Nov 17;167(5):1264-1280.e18
Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice.
Lee EH, Oh JH, Selvaraj S, Park SM, Choi MS, Spanel R, Yoon S, Borlak J
Oncotarget 2016 Mar 22;7(12):14983-5017
Oncotarget 2016 Mar 22;7(12):14983-5017
High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.
Gulhane M, Murray L, Lourie R, Tong H, Sheng YH, Wang R, Kang A, Schreiber V, Wong KY, Magor G, Denman S, Begun J, Florin TH, Perkins A, Cuív PÓ, McGuckin MA, Hasnain SZ
Scientific reports 2016 Jun 28;6:28990
Scientific reports 2016 Jun 28;6:28990
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM
Cancer research 2016 Jun 15;76(12):3629-43
Cancer research 2016 Jun 15;76(12):3629-43
Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques.
Vargas-Inchaustegui DA, Demers A, Shaw JM, Kang G, Ball D, Tuero I, Musich T, Mohanram V, Demberg T, Karpova TS, Li Q, Robert-Guroff M
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1700-10
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1700-10
IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran NL, Aiolfi R, Marra P, Esposito A, Cipriani F, Aldrighetti L, Iannacone M, Naldini L, Guidotti LG, Sitia G
EMBO molecular medicine 2016 Feb 1;8(2):155-70
EMBO molecular medicine 2016 Feb 1;8(2):155-70
Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells.
Schneider S, Gruart A, Grade S, Zhang Y, Kröger S, Kirchhoff F, Eichele G, Delgado García JM, Dimou L
Glia 2016 Dec;64(12):2201-2218
Glia 2016 Dec;64(12):2201-2218
Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers.
Liu YX, Wang KR, Xing H, Zhai XJ, Wang LP, Wang W
Oncology letters 2016 Aug;12(2):1240-1256
Oncology letters 2016 Aug;12(2):1240-1256
Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique.
Ware MJ, Colbert K, Keshishian V, Ho J, Corr SJ, Curley SA, Godin B
Tissue engineering. Part C, Methods 2016 Apr;22(4):312-21
Tissue engineering. Part C, Methods 2016 Apr;22(4):312-21
Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus.
Mehta FF, Son J, Hewitt SC, Jang E, Lydon JP, Korach KS, Chung SH
Oncotarget 2016 Apr 5;7(14):17455-67
Oncotarget 2016 Apr 5;7(14):17455-67
Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease.
Dang AK, Tesfagiorgis Y, Jain RW, Craig HC, Kerfoot SM
Frontiers in immunology 2015;6:470
Frontiers in immunology 2015;6:470
A challenging case of ocular melanoma.
Costache M, Dumitru AV, Pătraşcu OM, Popa-Cherecheanu DA, Bădilă P, Miu JC, Procop A, Popa M, Tampa MŞ, Sajin M, Simionescu O, Cîrstoiu MM
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2015;56(2 Suppl):817-22
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2015;56(2 Suppl):817-22
Missense Mutations in Exons 18-24 of EGFR in Hepatocellular Carcinoma Tissues.
Panvichian R, Tantiwetrueangdet A, Sornmayura P, Leelaudomlipi S
BioMed research international 2015;2015:171845
BioMed research international 2015;2015:171845
Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.
Dodbiba L, Teichman J, Fleet A, Thai H, Starmans MH, Navab R, Chen Z, Girgis H, Eng L, Espin-Garcia O, Shen X, Bandarchi B, Schwock J, Tsao MS, El-Zimaity H, Der SD, Xu W, Bristow RG, Darling GE, Boutros PC, Ailles LE, Liu G
PloS one 2015;10(3):e0121872
PloS one 2015;10(3):e0121872
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.
Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB
PloS one 2015;10(3):e0121707
PloS one 2015;10(3):e0121707
KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice.
Sin SH, Kim Y, Eason A, Dittmer DP
PLoS pathogens 2015 Sep;11(9):e1005135
PLoS pathogens 2015 Sep;11(9):e1005135
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Mu X, Español-Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, Lemaigre FP, Adili A, Yuan D, Weber A, Unger K, Heikenwälder M, Leclercq IA, Schwabe RF
The Journal of clinical investigation 2015 Oct 1;125(10):3891-903
The Journal of clinical investigation 2015 Oct 1;125(10):3891-903
Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.
Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K
Nature medicine 2015 Nov;21(11):1272-9
Nature medicine 2015 Nov;21(11):1272-9
Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region.
Liu W, Zhou H, Liu L, Zhao C, Deng Y, Chen L, Wu L, Mandrycky N, McNabb CT, Peng Y, Fuchs PN, Lu J, Sheen V, Qiu M, Mao M, Lu QR
Neurobiology of disease 2015 May;77:106-16
Neurobiology of disease 2015 May;77:106-16
The effect of pomegranate fruit extract on testosterone-induced BPH in rats.
Ammar AE, Esmat A, Hassona MD, Tadros MG, Abdel-Naim AB, Guns ES
The Prostate 2015 May;75(7):679-92
The Prostate 2015 May;75(7):679-92
Does the WHO 2010 classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas?
Hijioka S, Hosoda W, Mizuno N, Hara K, Imaoka H, Bhatia V, Mekky MA, Tajika M, Tanaka T, Ishihara M, Yogi T, Tsutumi H, Fujiyoshi T, Sato T, Hieda N, Yoshida T, Okuno N, Shimizu Y, Yatabe Y, Niwa Y, Yamao K
Journal of gastroenterology 2015 May;50(5):564-72
Journal of gastroenterology 2015 May;50(5):564-72
Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture.
Chow LT
Pathology, research and practice 2015 May;211(5):409-14
Pathology, research and practice 2015 May;211(5):409-14
Castration-resistant Lgr5(+) cells are long-lived stem cells required for prostatic regeneration.
Wang BE, Wang X, Long JE, Eastham-Anderson J, Firestein R, Junttila MR
Stem cell reports 2015 May 12;4(5):768-79
Stem cell reports 2015 May 12;4(5):768-79
P16(INK 4a) and Ki-67 expression in human papilloma virus-related head and neck mucosal lesions.
Gültekin SE, Sengüven B, Klussmann JP, Dienes HP
Investigacion clinica 2015 Mar;56(1):47-59
Investigacion clinica 2015 Mar;56(1):47-59
Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma--a clinical, histologic and immunohistochemical study.
Akrish S, Ben-Izhak O, Sabo E, Rachmiel A
Oral surgery, oral medicine, oral pathology and oral radiology 2015 Mar;119(3):318-25
Oral surgery, oral medicine, oral pathology and oral radiology 2015 Mar;119(3):318-25
Site-specific programming of the host epithelial transcriptome by the gut microbiota.
Sommer F, Nookaew I, Sommer N, Fogelstrand P, Bäckhed F
Genome biology 2015 Mar 28;16(1):62
Genome biology 2015 Mar 28;16(1):62
Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity.
Licht T, Dor-Wollman T, Ben-Zvi A, Rothe G, Keshet E
The Journal of clinical investigation 2015 Mar 2;125(3):1319-28
The Journal of clinical investigation 2015 Mar 2;125(3):1319-28
In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.
Rizzi N, Manni I, Vantaggiato C, Delledonne GA, Gentileschi MP, Maggi A, Piaggio G, Ciana P
Toxicological sciences : an official journal of the Society of Toxicology 2015 Jun;145(2):296-306
Toxicological sciences : an official journal of the Society of Toxicology 2015 Jun;145(2):296-306
Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.
Evason KJ, Francisco MT, Juric V, Balakrishnan S, Lopez Pazmino Mdel P, Gordan JD, Kakar S, Spitsbergen J, Goga A, Stainier DY
PLoS genetics 2015 Jul;11(7):e1005305
PLoS genetics 2015 Jul;11(7):e1005305
Combination strategy targeting VEGF and HGF/c-met in human renal cell carcinoma models.
Ciamporcero E, Miles KM, Adelaiye R, Ramakrishnan S, Shen L, Ku S, Pizzimenti S, Sennino B, Barrera G, Pili R
Molecular cancer therapeutics 2015 Jan;14(1):101-10
Molecular cancer therapeutics 2015 Jan;14(1):101-10
p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.
Zuo W, Zhang T, Wu DZ, Guan SP, Liew AA, Yamamoto Y, Wang X, Lim SJ, Vincent M, Lessard M, Crum CP, Xian W, McKeon F
Nature 2015 Jan 29;517(7536):616-20
Nature 2015 Jan 29;517(7536):616-20
Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy.
Meinke P, Schneiderat P, Srsen V, Korfali N, Lê Thành P, Cowan GJ, Cavanagh DR, Wehnert M, Schirmer EC, Walter MC
Neuromuscular disorders : NMD 2015 Feb;25(2):127-36
Neuromuscular disorders : NMD 2015 Feb;25(2):127-36
Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.
Wright MC, Reed-Geaghan EG, Bolock AM, Fujiyama T, Hoshino M, Maricich SM
The Journal of cell biology 2015 Feb 2;208(3):367-79
The Journal of cell biology 2015 Feb 2;208(3):367-79
Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.
Zhang P, Kumar A, Katz LS, Li L, Paulynice M, Herman MA, Scott DK
Diabetes 2015 Dec;64(12):4158-70
Diabetes 2015 Dec;64(12):4158-70
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, Browning JL, Goossens N, Nakagawa S, Gunasekaran G, Schwartz ME, Kobayashi M, Kumada H, Berger M, Pappo O, Rajewsky K, Hoshida Y, Karin M, Heikenwalder M, Ben-Neriah Y, Pikarsky E
Nature immunology 2015 Dec;16(12):1235-44
Nature immunology 2015 Dec;16(12):1235-44
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.
Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R
Cell reports 2015 Aug 4;12(5):760-73
Cell reports 2015 Aug 4;12(5):760-73
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt AW, Anderson S, Moskalev I, Haegert A, Alshalalfa M, Erho N, Davicioni E, Fazli L, Li E, Collins C, Wang Y, Black PC
Oncotarget 2015 Aug 28;6(25):21522-32
Oncotarget 2015 Aug 28;6(25):21522-32
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
O'Shaughnessy-Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B
Development (Cambridge, England) 2015 Aug 1;142(15):2586-97
Development (Cambridge, England) 2015 Aug 1;142(15):2586-97
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF
Nature medicine 2015 Apr;21(4):383-8
Nature medicine 2015 Apr;21(4):383-8
Retrospective analysis of metastatic behaviour of breast cancer subtypes.
Savci-Heijink CD, Halfwerk H, Hooijer GK, Horlings HM, Wesseling J, van de Vijver MJ
Breast cancer research and treatment 2015 Apr;150(3):547-57
Breast cancer research and treatment 2015 Apr;150(3):547-57
IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment.
Kinose Y, Sawada K, Makino H, Ogura T, Mizuno T, Suzuki N, Fujikawa T, Morii E, Nakamura K, Sawada I, Toda A, Hashimoto K, Isobe A, Mabuchi S, Ohta T, Itai A, Morishige K, Kurachi H, Kimura T
Molecular cancer therapeutics 2015 Apr;14(4):909-19
Molecular cancer therapeutics 2015 Apr;14(4):909-19
Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI.
Bechet D, Auger F, Couleaud P, Marty E, Ravasi L, Durieux N, Bonnet C, Plénat F, Frochot C, Mordon S, Tillement O, Vanderesse R, Lux F, Perriat P, Guillemin F, Barberi-Heyob M
Nanomedicine : nanotechnology, biology, and medicine 2015 Apr;11(3):657-70
Nanomedicine : nanotechnology, biology, and medicine 2015 Apr;11(3):657-70
Novel epigenetic target therapy for prostate cancer: a preclinical study.
Naldi I, Taranta M, Gherardini L, Pelosi G, Viglione F, Grimaldi S, Pani L, Cinti C
PloS one 2014;9(5):e98101
PloS one 2014;9(5):e98101
Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin.
Krabbe C, Bak ST, Jensen P, von Linstow C, Martínez Serrano A, Hansen C, Meyer M
PloS one 2014;9(5):e96465
PloS one 2014;9(5):e96465
Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.
Helm O, Mennrich R, Petrick D, Goebel L, Freitag-Wolf S, Röder C, Kalthoff H, Röcken C, Sipos B, Kabelitz D, Schäfer H, Oberg HH, Wesch D, Sebens S
PloS one 2014;9(5):e94357
PloS one 2014;9(5):e94357
Conditioned medium from hypoxic bone marrow-derived mesenchymal stem cells enhances wound healing in mice.
Chen L, Xu Y, Zhao J, Zhang Z, Yang R, Xie J, Liu X, Qi S
PloS one 2014;9(4):e96161
PloS one 2014;9(4):e96161
Effects of siRNA on RET/PTC3 junction oncogene in papillary thyroid carcinoma: from molecular and cellular studies to preclinical investigations.
Ali HM, Urbinati G, Chapuis H, Desmaele D, Bertrand JR, Couvreur P, Massaad-Massade L
PloS one 2014;9(4):e95964
PloS one 2014;9(4):e95964
Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.
Schleifman EB, Desai R, Spoerke JM, Xiao Y, Wong C, Abbas I, O'Brien C, Patel R, Sumiyoshi T, Fu L, Tam RN, Koeppen H, Wilson TR, Raja R, Hampton GM, Lackner MR
PloS one 2014;9(2):e88401
PloS one 2014;9(2):e88401
Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline.
Choe Y, Zarbalis KS, Pleasure SJ
PloS one 2014;9(2):e86025
PloS one 2014;9(2):e86025
Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas.
Sundberg JP, Stearns TM, Joh J, Proctor M, Ingle A, Silva KA, Dadras SS, Jenson AB, Ghim SJ
PloS one 2014;9(12):e113582
PloS one 2014;9(12):e113582
Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.
Pulskens WP, Butter LM, Teske GJ, Claessen N, Dessing MC, Flavell RA, Sutterwala FS, Florquin S, Leemans JC
PloS one 2014;9(1):e85775
PloS one 2014;9(1):e85775
Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids.
Farioli-Vecchioli S, Ceccarelli M, Saraulli D, Micheli L, Cannas S, D'Alessandro F, Scardigli R, Leonardi L, Cinà I, Costanzi M, Mattera A, Cestari V, Tirone F
Frontiers in cellular neuroscience 2014;8:98
Frontiers in cellular neuroscience 2014;8:98
n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice.
Cutuli D, De Bartolo P, Caporali P, Laricchiuta D, Foti F, Ronci M, Rossi C, Neri C, Spalletta G, Caltagirone C, Farioli-Vecchioli S, Petrosini L
Frontiers in aging neuroscience 2014;6:220
Frontiers in aging neuroscience 2014;6:220
High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice.
Mo C, Pang TY, Ransome MI, Hill RA, Renoir T, Hannan AJ
Neurobiology of disease 2014 Sep;69:248-62
Neurobiology of disease 2014 Sep;69:248-62
μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche.
Contet C, Kim A, Le D, Iyengar SK, Kotzebue RW, Yuan CJ, Kieffer BL, Mandyam CD
Addiction biology 2014 Sep;19(5):770-80
Addiction biology 2014 Sep;19(5):770-80
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.
Boxer LD, Barajas B, Tao S, Zhang J, Khavari PA
Genes & development 2014 Sep 15;28(18):2013-26
Genes & development 2014 Sep 15;28(18):2013-26
Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.
Fernando CV, Kele J, Bye CR, Niclis JC, Alsanie W, Blakely BD, Stenman J, Turner BJ, Parish CL
Stem cells and development 2014 Sep 1;23(17):1991-2003
Stem cells and development 2014 Sep 1;23(17):1991-2003
The kidney is the principal organ mediating klotho effects.
Lindberg K, Amin R, Moe OW, Hu MC, Erben RG, Östman Wernerson A, Lanske B, Olauson H, Larsson TE
Journal of the American Society of Nephrology : JASN 2014 Oct;25(10):2169-75
Journal of the American Society of Nephrology : JASN 2014 Oct;25(10):2169-75
The kinetics of ER fusion protein activation in vivo.
Wilson CH, Gamper I, Perfetto A, Auw J, Littlewood TD, Evan GI
Oncogene 2014 Oct 2;33(40):4877-80
Oncogene 2014 Oct 2;33(40):4877-80
Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.
Steward O, Sharp KG, Yee KM, Hatch MN, Bonner JF
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Oct 15;34(42):14013-21
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Oct 15;34(42):14013-21
Histone deacetylase expression in white matter oligodendrocytes after stroke.
Kassis H, Chopp M, Liu XS, Shehadah A, Roberts C, Zhang ZG
Neurochemistry international 2014 Nov;77:17-23
Neurochemistry international 2014 Nov;77:17-23
Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.
Sackmann-Sala L, Chiche A, Mosquera-Garrote N, Boutillon F, Cordier C, Pourmir I, Pascual-Mathey L, Kessal K, Pigat N, Camparo P, Goffin V
The American journal of pathology 2014 Nov;184(11):3105-19
The American journal of pathology 2014 Nov;184(11):3105-19
WFDC1 is a key modulator of inflammatory and wound repair responses.
Ressler SJ, Dang TD, Wu SM, Tse DY, Gilbert BE, Vyakarnam A, Yang F, Schauer IG, Barron DA, Rowley DR
The American journal of pathology 2014 Nov;184(11):2951-64
The American journal of pathology 2014 Nov;184(11):2951-64
CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.
Wang T, Guo S, Liu Z, Wu L, Li M, Yang J, Chen R, Liu X, Xu H, Cai S, Chen H, Li W, Xu S, Wang L, Hu Z, Zhuang Q, Wang L, Wu K, Liu J, Ye Z, Ji JY, Wang C, Chen K
Oncotarget 2014 Nov 15;5(21):10293-306
Oncotarget 2014 Nov 15;5(21):10293-306
Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance.
Queiroz KC, Shi K, Duitman J, Aberson HL, Wilmink JW, van Noesel CJ, Richel DJ, Spek CA
International journal of cancer 2014 Nov 15;135(10):2294-304
International journal of cancer 2014 Nov 15;135(10):2294-304
RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.
McDonald L, Ferrari N, Terry A, Bell M, Mohammed ZM, Orange C, Jenkins A, Muller WJ, Gusterson BA, Neil JC, Edwards J, Morris JS, Cameron ER, Blyth K
Disease models & mechanisms 2014 May;7(5):525-34
Disease models & mechanisms 2014 May;7(5):525-34
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
Mirzaa G, Parry DA, Fry AE, Giamanco KA, Schwartzentruber J, Vanstone M, Logan CV, Roberts N, Johnson CA, Singh S, Kholmanskikh SS, Adams C, Hodge RD, Hevner RF, Bonthron DT, Braun KPJ, Faivre L, Rivière JB, St-Onge J, Gripp KW, Mancini GM, Pang K, Sweeney E, van Esch H, Verbeek N, Wieczorek D, Steinraths M, Majewski J, FORGE Canada Consortium, Boycot KM, Pilz DT, Ross ME, Dobyns WB, Sheridan EG
Nature genetics 2014 May;46(5):510-515
Nature genetics 2014 May;46(5):510-515
Activation of cutaneous immune responses in complex regional pain syndrome.
Birklein F, Drummond PD, Li W, Schlereth T, Albrecht N, Finch PM, Dawson LF, Clark JD, Kingery WS
The journal of pain 2014 May;15(5):485-95
The journal of pain 2014 May;15(5):485-95
The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Baker MD, Ezzati M, Aloisio GM, Tarnawa ED, Cuevas I, Nakada Y, Castrillon DH
Reproduction (Cambridge, England) 2014 May;147(5):615-25
Reproduction (Cambridge, England) 2014 May;147(5):615-25
Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
Li A, Morton JP, Ma Y, Karim SA, Zhou Y, Faller WJ, Woodham EF, Morris HT, Stevenson RP, Juin A, Jamieson NB, MacKay CJ, Carter CR, Leung HY, Yamashiro S, Blyth K, Sansom OJ, Machesky LM
Gastroenterology 2014 May;146(5):1386-96.e1-17
Gastroenterology 2014 May;146(5):1386-96.e1-17
High-risk human papillomavirus load and biomarkers in cervical intraepithelial neoplasia and cancer.
Chang MS, Oh S, Jung EJ, Park JH, Jeon HW, Lee TS, Kim JH, Choi E, Byeon SJ, Park IA
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2014 May;122(5):427-36
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2014 May;122(5):427-36
Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury.
Li K, Nicaise C, Sannie D, Hala TJ, Javed E, Parker JL, Putatunda R, Regan KA, Suain V, Brion JP, Rhoderick F, Wright MC, Poulsen DJ, Lepore AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 May 28;34(22):7622-38
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 May 28;34(22):7622-38
Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation.
Xiang D, Liu CC, Wang MJ, Li JX, Chen F, Yao H, Yu B, Lu L, Borjigin U, Chen YX, Zhong L, Wangensteen KJ, He ZY, Wang X, Hu YP
Cell death & disease 2014 May 22;5(5):e1252
Cell death & disease 2014 May 22;5(5):e1252
CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways.
Saba R, Wu Q, Saga Y
Developmental biology 2014 May 15;389(2):173-81
Developmental biology 2014 May 15;389(2):173-81
Cells of renin lineage take on a podocyte phenotype in aging nephropathy.
Pippin JW, Glenn ST, Krofft RD, Rusiniak ME, Alpers CE, Hudkins K, Duffield JS, Gross KW, Shankland SJ
American journal of physiology. Renal physiology 2014 May 15;306(10):F1198-209
American journal of physiology. Renal physiology 2014 May 15;306(10):F1198-209
Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival.
Li Q, Wijesekera O, Salas SJ, Wang JY, Zhu M, Aprhys C, Chaichana KL, Chesler DA, Zhang H, Smith CL, Guerrero-Cazares H, Levchenko A, Quinones-Hinojosa A
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 1;20(9):2375-87
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 1;20(9):2375-87
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Aghababaei M, Perdu S, Irvine K, Beristain AG
Molecular human reproduction 2014 Mar;20(3):235-49
Molecular human reproduction 2014 Mar;20(3):235-49
Degeneration, regeneration, and cicatrization after fat grafting: dynamic total tissue remodeling during the first 3 months.
Kato H, Mineda K, Eto H, Doi K, Kuno S, Kinoshita K, Kanayama K, Yoshimura K
Plastic and reconstructive surgery 2014 Mar;133(3):303e-313e
Plastic and reconstructive surgery 2014 Mar;133(3):303e-313e
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.
Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L
Genes & development 2014 Mar 1;28(5):438-50
Genes & development 2014 Mar 1;28(5):438-50
DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells.
Laos M, Anttonen T, Kirjavainen A, af Hällström T, Laiho M, Pirvola U
Aging 2014 Jun;6(6):496-510
Aging 2014 Jun;6(6):496-510
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast.
Scaling AL, Prossnitz ER, Hathaway HJ
Hormones & cancer 2014 Jun;5(3):146-160
Hormones & cancer 2014 Jun;5(3):146-160
The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas.
Unek G, Ozmen A, Mendilcioglu I, Simsek M, Korgun ET
Tissue & cell 2014 Jun;46(3):198-205
Tissue & cell 2014 Jun;46(3):198-205
Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values.
Cserni G, Vörös A, Liepniece-Karele I, Bianchi S, Vezzosi V, Grabau D, Sapino A, Castellano I, Regitnig P, Foschini MP, Zolota V, Varga Z, Figueiredo P, Decker T, Focke C, Kulka J, Kaya H, Reiner-Concin A, Amendoeira I, Callagy G, Caffrey E, Wesseling J, Wells C
Breast (Edinburgh, Scotland) 2014 Jun;23(3):259-63
Breast (Edinburgh, Scotland) 2014 Jun;23(3):259-63
Culture dimensionality influences the resistance of glioblastoma stem-like cells to multikinase inhibitors.
Fernandez-Fuente G, Mollinedo P, Grande L, Vazquez-Barquero A, Fernandez-Luna JL
Molecular cancer therapeutics 2014 Jun;13(6):1664-72
Molecular cancer therapeutics 2014 Jun;13(6):1664-72
Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.
Yeo EJ, Cassetta L, Qian BZ, Lewkowich I, Li JF, Stefater JA 3rd, Smith AN, Wiechmann LS, Wang Y, Pollard JW, Lang RA
Cancer research 2014 Jun 1;74(11):2962-73
Cancer research 2014 Jun 1;74(11):2962-73
Differentiation and histogenesis of syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: evidence for a common origin.
Boecker W, Stenman G, Loening T, Andersson MK, Sinn HP, Barth P, Oberhellmann F, Bos I, Berg T, Marusic Z, Samoilova V, Buchwalow I
Histopathology 2014 Jul;65(1):9-23
Histopathology 2014 Jul;65(1):9-23
Characterization of the 9L gliosarcoma implanted in the Fischer rat: an orthotopic model for a grade IV brain tumor.
Bouchet A, Bidart M, Miladi I, Le Clec'h C, Serduc R, Coutton C, Regnard P, Khalil E, Dufort S, Lemasson B, Laissue J, Pelletier L, Le Duc G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Jul;35(7):6221-33
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Jul;35(7):6221-33
Constructs of electrospun PLGA, compressed collagen and minced urothelium for minimally manipulated autologous bladder tissue expansion.
Ajalloueian F, Zeiai S, Fossum M, Hilborn JG
Biomaterials 2014 Jul;35(22):5741-8
Biomaterials 2014 Jul;35(22):5741-8
Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.
Zhang H, von Gise A, Liu Q, Hu T, Tian X, He L, Pu W, Huang X, He L, Cai CL, Camargo FD, Pu WT, Zhou B
The Journal of biological chemistry 2014 Jul 4;289(27):18681-92
The Journal of biological chemistry 2014 Jul 4;289(27):18681-92
CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.
Duitman J, Borensztajn KS, Pulskens WP, Leemans JC, Florquin S, Spek CA
Laboratory investigation; a journal of technical methods and pathology 2014 Jan;94(1):89-97
Laboratory investigation; a journal of technical methods and pathology 2014 Jan;94(1):89-97
Contribution of mesenchymal proliferation in tooth root morphogenesis.
Sohn WJ, Choi MA, Yamamoto H, Lee S, Lee Y, Jung JK, Jin MU, An CH, Jung HS, Suh JY, Shin HI, Kim JY
Journal of dental research 2014 Jan;93(1):78-83
Journal of dental research 2014 Jan;93(1):78-83
Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells.
Mitterberger MC, Lechner S, Mattesich M, Zwerschke W
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Jan;69(1):13-24
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Jan;69(1):13-24
AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.
Merlen G, Gentric G, Celton-Morizur S, Foretz M, Guidotti JE, Fauveau V, Leclerc J, Viollet B, Desdouets C
Journal of hepatology 2014 Jan;60(1):152-9
Journal of hepatology 2014 Jan;60(1):152-9
Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.
Corrales A, Vidal R, García S, Vidal V, Martínez P, García E, Flórez J, Sanchez-Barceló EJ, Martínez-Cué C, Rueda N
Journal of pineal research 2014 Jan;56(1):51-61
Journal of pineal research 2014 Jan;56(1):51-61
Evaluation of Ki-67 index in EUS-FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors.
Hasegawa T, Yamao K, Hijioka S, Bhatia V, Mizuno N, Hara K, Imaoka H, Niwa Y, Tajika M, Kondo S, Tanaka T, Shimizu Y, Kinoshita T, Kohsaki T, Nishimori I, Iwasaki S, Saibara T, Hosoda W, Yatabe Y
Endoscopy 2014 Jan;46(1):32-8
Endoscopy 2014 Jan;46(1):32-8
Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations.
Calibasi G, Baskin Y, Alyuruk H, Cavas L, Oztop I, Sagol O, Atila K, Ellidokuz H, Yilmaz U
Applied immunohistochemistry & molecular morphology : AIMM 2014 Jan;22(1):37-45
Applied immunohistochemistry & molecular morphology : AIMM 2014 Jan;22(1):37-45
Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver.
Maczuga P, Verheij J, van der Loos C, van Logtenstein R, Hooijer G, Martier R, Borel F, Lubelski J, Koornneef A, Blits B, van Deventer S, Petry H, Konstantinova P
Gene therapy 2014 Jan;21(1):60-70
Gene therapy 2014 Jan;21(1):60-70
Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.
Kikuchi K, Hettmer S, Aslam MI, Michalek JE, Laub W, Wilky BA, Loeb DM, Rubin BP, Wagers AJ, Keller C
PLoS genetics 2014 Jan;10(1):e1004107
PLoS genetics 2014 Jan;10(1):e1004107
Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine.
Aronson BE, Stapleton KA, Vissers LA, Stokhuijzen E, Bruijnzeel H, Krasinski SD
BMC molecular biology 2014 Jan 28;15:3
BMC molecular biology 2014 Jan 28;15:3
FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.
Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM
Cancer research 2014 Jan 15;74(2):609-20
Cancer research 2014 Jan 15;74(2):609-20
P53-participated cellular and molecular responses to irradiation are cell differentiation-determined in murine intestinal epithelium.
Wang F, Cheng J, Liu D, Sun H, Zhao J, Wang J, Chen J, Su Y, Zou Z
Archives of biochemistry and biophysics 2014 Jan 15;542:21-7
Archives of biochemistry and biophysics 2014 Jan 15;542:21-7
Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration.
Formiga FR, Pelacho B, Garbayo E, Imbuluzqueta I, Díaz-Herráez P, Abizanda G, Gavira JJ, Simón-Yarza T, Albiasu E, Tamayo E, Prósper F, Blanco-Prieto MJ
Journal of controlled release : official journal of the Controlled Release Society 2014 Jan 10;173:132-9
Journal of controlled release : official journal of the Controlled Release Society 2014 Jan 10;173:132-9
NANOS2 promotes male germ cell development independent of meiosis suppression.
Saba R, Kato Y, Saga Y
Developmental biology 2014 Jan 1;385(1):32-40
Developmental biology 2014 Jan 1;385(1):32-40
G0-G1 transition and the restriction point in pancreatic β-cells in vivo.
Hija A, Salpeter S, Klochendler A, Grimsby J, Brandeis M, Glaser B, Dor Y
Diabetes 2014 Feb;63(2):578-84
Diabetes 2014 Feb;63(2):578-84
Immunohistochemical distribution of cell cycle proteins p27, p57, cyclin D3, PCNA and Ki67 in normal and diabetic human placentas.
Unek G, Ozmen A, Mendilcioglu I, Simsek M, Korgun ET
Journal of molecular histology 2014 Feb;45(1):21-34
Journal of molecular histology 2014 Feb;45(1):21-34
MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.
Grzmil M, Huber RM, Hess D, Frank S, Hynx D, Moncayo G, Klein D, Merlo A, Hemmings BA
The Journal of clinical investigation 2014 Feb;124(2):742-54
The Journal of clinical investigation 2014 Feb;124(2):742-54
Solitary tumours associated with Jaagsiekte retrovirus in sheep are heterogeneous and contain cells expressing markers identifying progenitor cells in lung repair.
De las Heras M, de Martino A, Borobia M, Ortín A, Álvarez R, Borderías L, Giménez-Más JA
Journal of comparative pathology 2014 Feb-Apr;150(2-3):138-47
Journal of comparative pathology 2014 Feb-Apr;150(2-3):138-47
Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration.
Metcalfe C, Kljavin NM, Ybarra R, de Sauvage FJ
Cell stem cell 2014 Feb 6;14(2):149-59
Cell stem cell 2014 Feb 6;14(2):149-59
Expression of a Y-located human proto-oncogene TSPY in a transgenic mouse model of prostate cancer.
Kido T, Schubert S, Hatakeyama S, Ohyama C, Schmidtke J, Lau YF
Cell & bioscience 2014 Feb 17;4(1):9
Cell & bioscience 2014 Feb 17;4(1):9
Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.
Barceló C, Paco N, Morell M, Alvarez-Moya B, Bota-Rabassedas N, Jaumot M, Vilardell F, Capella G, Agell N
Cancer research 2014 Feb 15;74(4):1190-9
Cancer research 2014 Feb 15;74(4):1190-9
Birthdating of myenteric neuron subtypes in the small intestine of the mouse.
Bergner AJ, Stamp LA, Gonsalvez DG, Allison MB, Olson DP, Myers MG Jr, Anderson CR, Young HM
The Journal of comparative neurology 2014 Feb 15;522(3):514-27
The Journal of comparative neurology 2014 Feb 15;522(3):514-27
Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.
Hoos A, Protsyuk D, Borsig L
Cancer research 2014 Feb 1;74(3):695-704
Cancer research 2014 Feb 1;74(3):695-704
Tumor vascularization is critical for oncolytic vaccinia virus treatment of peritoneal carcinomatosis.
Ottolino-Perry K, Tang N, Head R, Ng C, Arulanandam R, Angarita FA, Acuna SA, Chen Y, Bell J, Dacosta RS, McCart JA
International journal of cancer 2014 Feb 1;134(3):717-30
International journal of cancer 2014 Feb 1;134(3):717-30
Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche.
Schotanus BA, Kruitwagen HS, van den Ingh TS, van Wolferen ME, Rothuizen J, Penning LC, Spee B
BMC veterinary research 2014 Dec 31;10:309
BMC veterinary research 2014 Dec 31;10:309
Temsirolimus combined with cisplatin or bevacizumab is active in osteosarcoma models.
Fleuren ED, Versleijen-Jonkers YM, Roeffen MH, Franssen GM, Flucke UE, Houghton PJ, Oyen WJ, Boerman OC, van der Graaf WT
International journal of cancer 2014 Dec 15;135(12):2770-82
International journal of cancer 2014 Dec 15;135(12):2770-82
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P
Haematologica 2014 Aug;99(8):1356-64
Haematologica 2014 Aug;99(8):1356-64
MET expression is associated with disease-specific survival in breast cancer patients in the neoadjuvant setting.
Koh YW, Lee HJ, Ahn JH, Lee JW, Gong G
Pathology, research and practice 2014 Aug;210(8):494-500
Pathology, research and practice 2014 Aug;210(8):494-500
MYC synergizes with activated BRAFV600E in mouse lung tumor development by suppressing senescence.
Tabor V, Bocci M, Alikhani N, Kuiper R, Larsson LG
Cancer research 2014 Aug 15;74(16):4222-9
Cancer research 2014 Aug 15;74(16):4222-9
Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype.
Larrayoz M, Pio R, Pajares MJ, Zudaire I, Ajona D, Casanovas O, Montuenga LM, Agorreta J
EMBO molecular medicine 2014 Apr;6(4):539-50
EMBO molecular medicine 2014 Apr;6(4):539-50
Bronchiolar remodeling in adult mice following neonatal exposure to hyperoxia: relation to growth.
O'Reilly M, Hansbro PM, Horvat JC, Beckett EL, Harding R, Sozo F
Anatomical record (Hoboken, N.J. : 2007) 2014 Apr;297(4):758-69
Anatomical record (Hoboken, N.J. : 2007) 2014 Apr;297(4):758-69
Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex.
Bando Y, Hirano T, Tagawa Y
Cerebral cortex (New York, N.Y. : 1991) 2014 Apr;24(4):1017-29
Cerebral cortex (New York, N.Y. : 1991) 2014 Apr;24(4):1017-29
Immunolocalization of cell cycle proteins (p57, p27, cyclin D3, PCNA and Ki67) in intrauterine growth retardation (IUGR) and normal human term placentas.
Unek G, Ozmen A, Ozekinci M, Sakinci M, Korgun ET
Acta histochemica 2014 Apr;116(3):493-502
Acta histochemica 2014 Apr;116(3):493-502
Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1α,25(OH)2 and 25(OH) vitamin D.
Mapes B, Chase M, Hong E, Ludvik A, Ceryes K, Huang Y, Kupfer SS
Physiological genomics 2014 Apr 15;46(8):302-8
Physiological genomics 2014 Apr 15;46(8):302-8
Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury.
Sörensen-Zender I, Rong S, Susnik N, Zender S, Pennekamp P, Melk A, Haller H, Schmitt R
American journal of physiology. Renal physiology 2014 Apr 15;306(8):F907-15
American journal of physiology. Renal physiology 2014 Apr 15;306(8):F907-15
An integrated computational/experimental model of lymphoma growth.
Frieboes HB, Smith BR, Chuang YL, Ito K, Roettgers AM, Gambhir SS, Cristini V
PLoS computational biology 2013;9(3):e1003008
PLoS computational biology 2013;9(3):e1003008
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
Schaffer AE, Taylor BL, Benthuysen JR, Liu J, Thorel F, Yuan W, Jiao Y, Kaestner KH, Herrera PL, Magnuson MA, May CL, Sander M
PLoS genetics 2013;9(1):e1003274
PLoS genetics 2013;9(1):e1003274
Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.
Yang X, La Rosa FG, Genova EE, Huber K, Schaack J, Degregori J, Serkova NJ, Li Y, Su LJ, Kessler E, Flaig TW
PloS one 2013;8(9):e74809
PloS one 2013;8(9):e74809
TLR2 mediates Helicobacter pylori-induced tolerogenic immune response in mice.
Sun X, Zhang M, El-Zataari M, Owyang SY, Eaton KA, Liu M, Chang YM, Zou W, Kao JY
PloS one 2013;8(9):e74595
PloS one 2013;8(9):e74595
Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells.
Osawa Y, Hoshi M, Yasuda I, Saibara T, Moriwaki H, Kozawa O
PloS one 2013;8(6):e65251
PloS one 2013;8(6):e65251
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
El-Zaatari M, Kao JY, Tessier A, Bai L, Hayes MM, Fontaine C, Eaton KA, Merchant JL
PloS one 2013;8(3):e58935
PloS one 2013;8(3):e58935
Multiple delivery of siRNA against endoglin into murine mammary adenocarcinoma prevents angiogenesis and delays tumor growth.
Dolinsek T, Markelc B, Sersa G, Coer A, Stimac M, Lavrencak J, Brozic A, Kranjc S, Cemazar M
PloS one 2013;8(3):e58723
PloS one 2013;8(3):e58723
Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2.
Navis AC, Bourgonje A, Wesseling P, Wright A, Hendriks W, Verrijp K, van der Laak JA, Heerschap A, Leenders WP
PloS one 2013;8(3):e58262
PloS one 2013;8(3):e58262
CoupTFI interacts with retinoic acid signaling during cortical development.
Harrison-Uy SJ, Siegenthaler JA, Faedo A, Rubenstein JL, Pleasure SJ
PloS one 2013;8(3):e58219
PloS one 2013;8(3):e58219
Tissue engineered skin substitutes created by laser-assisted bioprinting form skin-like structures in the dorsal skin fold chamber in mice.
Michael S, Sorg H, Peck CT, Koch L, Deiwick A, Chichkov B, Vogt PM, Reimers K
PloS one 2013;8(3):e57741
PloS one 2013;8(3):e57741
Tumor stress-induced phosphoprotein1 (STIP1) as a prognostic biomarker in ovarian cancer.
Chao A, Lai CH, Tsai CL, Hsueh S, Hsueh C, Lin CY, Chou HH, Lin YJ, Chen HW, Chang TC, Wang TH
PloS one 2013;8(2):e57084
PloS one 2013;8(2):e57084
Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis.
Maruyama EO, Yu HM, Jiang M, Fu J, Hsu W
PloS one 2013;8(2):e56644
PloS one 2013;8(2):e56644
Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats.
Khan R, Khan AQ, Lateef A, Rehman MU, Tahir M, Ali F, Hamiza OO, Sultana S
PloS one 2013;8(2):e56020
PloS one 2013;8(2):e56020
Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.
Osada M, Singh VJ, Wu K, Sant'Angelo DB, Pezzano M
PloS one 2013;8(12):e83024
PloS one 2013;8(12):e83024
Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.
Yumoto T, Nakadate K, Nakamura Y, Sugitani Y, Sugitani-Yoshida R, Ueda S, Sakakibara S
PloS one 2013;8(11):e79895
PloS one 2013;8(11):e79895
Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.
Fry EA, Taneja P, Maglic D, Zhu S, Sui G, Inoue K
PloS one 2013;8(10):e77870
PloS one 2013;8(10):e77870
Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo.
Rousalova I, Banerjee S, Sangwan V, Evenson K, McCauley JA, Kratzke R, Vickers SM, Saluja A, D'Cunha J
PloS one 2013;8(10):e77411
PloS one 2013;8(10):e77411
A husband and a wife with simultaneous presentation of glioblastoma multiforme: a case report.
Roviello G, Petrioli R, Cerase A, Marsili S, Miracco C, Rubino G, Tini P
Case reports in oncology 2013;6(3):538-43
Case reports in oncology 2013;6(3):538-43
Insulinoma diagnosed as drug-refractory epilepsy in an adolescent boy: a case report.
Horváth E, Gozar H, Chira L, Dunca I, Kiss E, Pávai Z
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(4):1147-51
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(4):1147-51
APC/C-Cdh1 coordinates neurogenesis and cortical size during development.
Delgado-Esteban M, García-Higuera I, Maestre C, Moreno S, Almeida A
Nature communications 2013;4:2879
Nature communications 2013;4:2879
Aldara activates TLR7-independent immune defence.
Walter A, Schäfer M, Cecconi V, Matter C, Urosevic-Maiwald M, Belloni B, Schönewolf N, Dummer R, Bloch W, Werner S, Beer HD, Knuth A, van den Broek M
Nature communications 2013;4:1560
Nature communications 2013;4:1560
Enhanced oxygen supply improves islet viability in a new bioartificial pancreas.
Barkai U, Weir GC, Colton CK, Ludwig B, Bornstein SR, Brendel MD, Neufeld T, Bremer C, Leon A, Evron Y, Yavriyants K, Azarov D, Zimermann B, Maimon S, Shabtay N, Balyura M, Rozenshtein T, Vardi P, Bloch K, de Vos P, Rotem A
Cell transplantation 2013;22(8):1463-76
Cell transplantation 2013;22(8):1463-76
Biological and demographic profile of meningiomas in a cohort of Egyptian patients: impact on tumor recurrence.
Abdelzaher E, El Deeb NM, Gowil AG, Yehya A
TheScientificWorldJournal 2013;2013:375139
TheScientificWorldJournal 2013;2013:375139
MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.
Gayle SS, Castellino RC, Buss MC, Nahta R
Current medicinal chemistry 2013;20(19):2486-99
Current medicinal chemistry 2013;20(19):2486-99
Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.
Wang S, Huang J, Lyu H, Cai B, Yang X, Li F, Tan J, Edgerton SM, Thor AD, Lee CK, Liu B
Breast cancer research : BCR 2013;15(5):R101
Breast cancer research : BCR 2013;15(5):R101
Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
Saad N, Esa NM, Ithnin H
Asian Pacific journal of cancer prevention : APJCP 2013;14(5):3093-9
Asian Pacific journal of cancer prevention : APJCP 2013;14(5):3093-9
Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
Saad N, Esa NM, Ithnin H
Asian Pacific journal of cancer prevention : APJCP 2013;14(5):3093-9
Asian Pacific journal of cancer prevention : APJCP 2013;14(5):3093-9
Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.
Nobs L, Nestel S, Kulik A, Nitsch C, Atanasoski S
Glia 2013 Sep;61(9):1443-55
Glia 2013 Sep;61(9):1443-55
Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas.
Deyrup AT, Chibon F, Guillou L, Lagarde P, Coindre JM, Weiss SW
The American journal of surgical pathology 2013 Sep;37(9):1373-8
The American journal of surgical pathology 2013 Sep;37(9):1373-8
Uterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.
Sun X, Bartos A, Whitsett JA, Dey SK
Molecular endocrinology (Baltimore, Md.) 2013 Sep;27(9):1492-501
Molecular endocrinology (Baltimore, Md.) 2013 Sep;27(9):1492-501
Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.
Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E
Cell stem cell 2013 Sep 5;13(3):285-99
Cell stem cell 2013 Sep 5;13(3):285-99
Role of fibrinogen in acute ischemic kidney injury.
Sörensen-Zender I, Rong S, Susnik N, Lange J, Gueler F, Degen JL, Melk A, Haller H, Schmitt R
American journal of physiology. Renal physiology 2013 Sep 1;305(5):F777-85
American journal of physiology. Renal physiology 2013 Sep 1;305(5):F777-85
Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.
Altan B, Yokobori T, Mochiki E, Ohno T, Ogata K, Ogawa A, Yanai M, Kobayashi T, Luvsandagva B, Asao T, Kuwano H
Carcinogenesis 2013 Oct;34(10):2314-21
Carcinogenesis 2013 Oct;34(10):2314-21
Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.
Zhu S, Mott RT, Fry EA, Taneja P, Kulik G, Sui G, Inoue K
The American journal of pathology 2013 Oct;183(4):1339-1350
The American journal of pathology 2013 Oct;183(4):1339-1350
Lack of high-dose radiation mediated prostate cancer promotion and low-dose radiation adaptive response in the TRAMP mouse model.
Lawrence MD, Ormsby RJ, Blyth BJ, Bezak E, England G, Newman MR, Tilley WD, Sykes PJ
Radiation research 2013 Oct;180(4):376-88
Radiation research 2013 Oct;180(4):376-88
Slow turning lateral vessel bioreactor improves embryoid body formation and cardiogenic differentiation of mouse embryonic stem cells.
Rungarunlert S, Klincumhom N, Tharasanit T, Techakumphu M, Pirity MK, Dinnyes A
Cellular reprogramming 2013 Oct;15(5):443-58
Cellular reprogramming 2013 Oct;15(5):443-58
Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases.
Smardencas A, Rizkalla K, Kim HA, Massalas J, O'Leary C, Ehrlich ME, Schütz G, Lawrence AJ, Drago J
BMC neuroscience 2013 Oct 3;14:111
BMC neuroscience 2013 Oct 3;14:111
Is Ki-67 expression prognostic for local relapse in early-stage breast cancer patients treated with breast conservation therapy (BCT)?
Hafeez F, Neboori HJ, Harigopal M, Wu H, Haffty BG, Yang Q, Schiff D, Moran MS
International journal of radiation oncology, biology, physics 2013 Oct 1;87(2):344-8
International journal of radiation oncology, biology, physics 2013 Oct 1;87(2):344-8
Targeting 5-HT(1A) receptors in astrocytes to protect dopaminergic neurons in Parkinsonian models.
Miyazaki I, Asanuma M, Murakami S, Takeshima M, Torigoe N, Kitamura Y, Miyoshi K
Neurobiology of disease 2013 Nov;59:244-56
Neurobiology of disease 2013 Nov;59:244-56
The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.
Vedin LL, Gustafsson JÅ, Steffensen KR
Molecular carcinogenesis 2013 Nov;52(11):835-44
Molecular carcinogenesis 2013 Nov;52(11):835-44
Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory.
Pristerà A, Saraulli D, Farioli-Vecchioli S, Strimpakos G, Costanzi M, di Certo MG, Cannas S, Ciotti MT, Tirone F, Mattei E, Cestari V, Canu N
Neurobiology of aging 2013 Nov;34(11):2551-63
Neurobiology of aging 2013 Nov;34(11):2551-63
The regulation of SOX7 and its tumor suppressive role in breast cancer.
Stovall DB, Wan M, Miller LD, Cao P, Maglic D, Zhang Q, Stampfer MR, Liu W, Xu J, Sui G
The American journal of pathology 2013 Nov;183(5):1645-1653
The American journal of pathology 2013 Nov;183(5):1645-1653
FDG PET in the evaluation of phaeochromocytoma: a correlative study with MIBG scintigraphy and Ki-67 proliferative index.
Lin M, Wong V, Yap J, Jin R, Leong P, Campbell P
Clinical imaging 2013 Nov-Dec;37(6):1084-8
Clinical imaging 2013 Nov-Dec;37(6):1084-8
Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.
Flanigan SA, Pitts TM, Newton TP, Kulikowski GN, Tan AC, McManus MC, Spreafico A, Kachaeva MI, Selby HM, Tentler JJ, Eckhardt SG, Leong S
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Nov 15;19(22):6219-29
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Nov 15;19(22):6219-29
The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells.
Huang J, Wang S, Lyu H, Cai B, Yang X, Wang J, Liu B
Molecular cancer 2013 Nov 11;12(1):134
Molecular cancer 2013 Nov 11;12(1):134
Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan.
Haug K, Azqueta A, Johnsen-Soriano S, Shahdadfar A, Drolsum LK, Moe MC, Røger MT, Romero FJ, Collins AR, Nicolaissen B
Acta ophthalmologica 2013 May;91(3):219-25
Acta ophthalmologica 2013 May;91(3):219-25
Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.
Ransome MI, Hannan AJ
Molecular and cellular neurosciences 2013 May;54:93-107
Molecular and cellular neurosciences 2013 May;54:93-107
Enhanced liver progenitor cell survival and differentiation in vivo by spheroid implantation in a vascularized tissue engineering chamber.
Yap KK, Dingle AM, Palmer JA, Dhillon RS, Lokmic Z, Penington AJ, Yeoh GC, Morrison WA, Mitchell GM
Biomaterials 2013 May;34(16):3992-4001
Biomaterials 2013 May;34(16):3992-4001
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development.
Maruyama T, Jiang M, Hsu W
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 May;28(5):1150-9
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 May;28(5):1150-9
miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin α5 expression.
Ohyagi-Hara C, Sawada K, Kamiura S, Tomita Y, Isobe A, Hashimoto K, Kinose Y, Mabuchi S, Hisamatsu T, Takahashi T, Kumasawa K, Nagata S, Morishige K, Lengyel E, Kurachi H, Kimura T
The American journal of pathology 2013 May;182(5):1876-89
The American journal of pathology 2013 May;182(5):1876-89
Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.
Bardehle S, Krüger M, Buggenthin F, Schwausch J, Ninkovic J, Clevers H, Snippert HJ, Theis FJ, Meyer-Luehmann M, Bechmann I, Dimou L, Götz M
Nature neuroscience 2013 May;16(5):580-6
Nature neuroscience 2013 May;16(5):580-6
A novel model of adenine-induced tubulointerstitial nephropathy in mice.
Jia T, Olauson H, Lindberg K, Amin R, Edvardsson K, Lindholm B, Andersson G, Wernerson A, Sabbagh Y, Schiavi S, Larsson TE
BMC nephrology 2013 May 30;14:116
BMC nephrology 2013 May 30;14:116
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
Navis AC, Niclou SP, Fack F, Stieber D, van Lith S, Verrijp K, Wright A, Stauber J, Tops B, Otte-Holler I, Wevers RA, van Rooij A, Pusch S, von Deimling A, Tigchelaar W, van Noorden CJ, Wesseling P, Leenders WP
Acta neuropathologica communications 2013 May 29;1:18
Acta neuropathologica communications 2013 May 29;1:18
The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus.
Li G, Fang L, Fernández G, Pleasure SJ
Neuron 2013 May 22;78(4):658-72
Neuron 2013 May 22;78(4):658-72
Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome.
Villegas LR, Kluck D, Field C, Oberley-Deegan RE, Woods C, Yeager ME, El Kasmi KC, Savani RC, Bowler RP, Nozik-Grayck E
Antioxidants & redox signaling 2013 May 10;18(14):1753-64
Antioxidants & redox signaling 2013 May 10;18(14):1753-64
Dynamics of senescent cell formation and retention revealed by p14ARF induction in the epidermis.
Tokarsky-Amiel R, Azazmeh N, Helman A, Stein Y, Hassan A, Maly A, Ben-Porath I
Cancer research 2013 May 1;73(9):2829-39
Cancer research 2013 May 1;73(9):2829-39
Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.
Ng TS, Wert D, Sohi H, Procissi D, Colcher D, Raubitschek AA, Jacobs RE
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 May 1;19(9):2518-27
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 May 1;19(9):2518-27
Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.
Esnault C, Cornelis G, Heidmann O, Heidmann T
PLoS genetics 2013 Mar;9(3):e1003400
PLoS genetics 2013 Mar;9(3):e1003400
VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain.
Baburamani AA, Castillo-Melendez M, Walker DW
Pediatric research 2013 Mar;73(3):310-6
Pediatric research 2013 Mar;73(3):310-6
Is survivin expression prognostic or predictive in malignant pleural mesothelioma?
Hmeljak J, Erčulj N, Dolžan V, Pižem J, Kern I, Kovač V, Cemažar M, Cör A
Virchows Archiv : an international journal of pathology 2013 Mar;462(3):315-21
Virchows Archiv : an international journal of pathology 2013 Mar;462(3):315-21
An in vivo screen of secreted proteins identifies adiponectin as a regulator of murine cutaneous wound healing.
Salathia NS, Shi J, Zhang J, Glynne RJ
The Journal of investigative dermatology 2013 Mar;133(3):812-821
The Journal of investigative dermatology 2013 Mar;133(3):812-821
Role of Langerhans cells, Ki-67 protein and apoptosis in acquired cholesteatoma: prospective clinical study.
Akdogan V, Yilmaz I, Canpolat T, Ozluoglu LN
The Journal of laryngology and otology 2013 Mar;127(3):252-9
The Journal of laryngology and otology 2013 Mar;127(3):252-9
Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies.
Thomas A, Patterson NH, Marcinkiewicz MM, Lazaris A, Metrakos P, Chaurand P
Analytical chemistry 2013 Mar 5;85(5):2860-6
Analytical chemistry 2013 Mar 5;85(5):2860-6
Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice.
Karim BO, Rhee KJ, Liu G, Zheng D, Huso DL
BMC cancer 2013 Mar 27;13:157
BMC cancer 2013 Mar 27;13:157
The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes.
Carlson LM, De Geer A, Sveinbjørnsson B, Orrego A, Martinsson T, Kogner P, Levitskaya J
Oncoimmunology 2013 Mar 1;2(3):e23618
Oncoimmunology 2013 Mar 1;2(3):e23618
Chemoprevention of lung squamous cell carcinoma by ginseng.
Pan J, Zhang Q, Li K, Liu Q, Wang Y, You M
Cancer prevention research (Philadelphia, Pa.) 2013 Jun;6(6):530-9
Cancer prevention research (Philadelphia, Pa.) 2013 Jun;6(6):530-9
Signature patterns of human papillomavirus type 16 in invasive anal carcinoma.
Valmary-Degano S, Jacquin E, Prétet JL, Monnien F, Girardo B, Arbez-Gindre F, Joly M, Bosset JF, Kantelip B, Mougin C
Human pathology 2013 Jun;44(6):992-1002
Human pathology 2013 Jun;44(6):992-1002
Transcription factor Sox11 is essential for both embryonic and adult neurogenesis.
Wang Y, Lin L, Lai H, Parada LF, Lei L
Developmental dynamics : an official publication of the American Association of Anatomists 2013 Jun;242(6):638-53
Developmental dynamics : an official publication of the American Association of Anatomists 2013 Jun;242(6):638-53
Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer.
Krüger K, Stefansson IM, Collett K, Arnes JB, Aas T, Akslen LA
Breast (Edinburgh, Scotland) 2013 Jun;22(3):282-8
Breast (Edinburgh, Scotland) 2013 Jun;22(3):282-8
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA
Nature immunology 2013 Jun;14(6):574-83
Nature immunology 2013 Jun;14(6):574-83
Expression of Lewis X is associated with poor prognosis in triple-negative breast cancer.
Koh YW, Lee HJ, Ahn JH, Lee JW, Gong G
American journal of clinical pathology 2013 Jun;139(6):746-53
American journal of clinical pathology 2013 Jun;139(6):746-53
Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosis.
Tsofack SP, Meunier L, Sanchez L, Madore J, Provencher D, Mes-Masson AM, Lebel M
BMC cancer 2013 Jun 22;13:303
BMC cancer 2013 Jun 22;13:303
FGFR1 is essential for prostate cancer progression and metastasis.
Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR
Cancer research 2013 Jun 15;73(12):3716-24
Cancer research 2013 Jun 15;73(12):3716-24
Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS.
Zhang J, Pippin JW, Krofft RD, Naito S, Liu ZH, Shankland SJ
American journal of physiology. Renal physiology 2013 Jun 1;304(11):F1375-89
American journal of physiology. Renal physiology 2013 Jun 1;304(11):F1375-89
State-dependent signaling by Cav1.2 regulates hair follicle stem cell function.
Yucel G, Altindag B, Gomez-Ospina N, Rana A, Panagiotakos G, Lara MF, Dolmetsch R, Oro AE
Genes & development 2013 Jun 1;27(11):1217-22
Genes & development 2013 Jun 1;27(11):1217-22
Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells.
You X, Liu F, Zhang T, Li Y, Ye L, Zhang X
Carcinogenesis 2013 Jul;34(7):1644-52
Carcinogenesis 2013 Jul;34(7):1644-52
SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein.
Kuo SJ, Lin HY, Chien SY, Chen DR
Oncology reports 2013 Jul;30(1):125-30
Oncology reports 2013 Jul;30(1):125-30
Characterization of WWOX inactivation in murine mammary gland development.
Abdeen SK, Salah Z, Khawaled S, Aqeilan RI
Journal of cellular physiology 2013 Jul;228(7):1391-6
Journal of cellular physiology 2013 Jul;228(7):1391-6
Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors.
Kara T, Serinsoz E, Arpaci RB, Gubur O, Orekici G, Ata A, Colak T, Arican A
Pathology, research and practice 2013 Jul;209(7):413-7
Pathology, research and practice 2013 Jul;209(7):413-7
The effects of ulipristal on Bax/Bcl-2, cytochrome c, Ki-67 and cyclooxygenase-2 expression in a rat model with surgically induced endometriosis.
Huniadi CA, Pop OL, Antal TA, Stamatian F
European journal of obstetrics, gynecology, and reproductive biology 2013 Jul;169(2):360-5
European journal of obstetrics, gynecology, and reproductive biology 2013 Jul;169(2):360-5
Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells.
Zhao XC, Dou GR, Wang L, Liang L, Tian DM, Cao XL, Qin HY, Wang CM, Zhang P, Han H
Neoplasia (New York, N.Y.) 2013 Jul;15(7):815-25
Neoplasia (New York, N.Y.) 2013 Jul;15(7):815-25
Changes in signaling pathways induced by vandetanib in a human medullary thyroid carcinoma model, as analyzed by reverse phase protein array.
Broutin S, Commo F, De Koning L, Marty-Prouvost B, Lacroix L, Talbot M, Caillou B, Dubois T, Ryan AJ, Dupuy C, Schlumberger M, Bidart JM
Thyroid : official journal of the American Thyroid Association 2013 Jul 3;
Thyroid : official journal of the American Thyroid Association 2013 Jul 3;
Lithium rescues synaptic plasticity and memory in Down syndrome mice.
Contestabile A, Greco B, Ghezzi D, Tucci V, Benfenati F, Gasparini L
The Journal of clinical investigation 2013 Jan;123(1):348-61
The Journal of clinical investigation 2013 Jan;123(1):348-61
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Takubo K, Nagamatsu G, Kobayashi CI, Nakamura-Ishizu A, Kobayashi H, Ikeda E, Goda N, Rahimi Y, Johnson RS, Soga T, Hirao A, Suematsu M, Suda T
Cell stem cell 2013 Jan 3;12(1):49-61
Cell stem cell 2013 Jan 3;12(1):49-61
A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord.
Garcia-Ovejero D, Arevalo-Martin A, Paniagua-Torija B, Sierra-Palomares Y, Molina-Holgado E
The Journal of comparative neurology 2013 Jan 1;521(1):233-51
The Journal of comparative neurology 2013 Jan 1;521(1):233-51
Expression of matrix metalloproteinase-13 and Ki-67 in nonmelanoma skin cancer in xeroderma pigmentosum and non-xeroderma pigmentosum.
El-Hawary AK, Yassin E, Khater A, Abdelgaber S
The American Journal of dermatopathology 2013 Feb;35(1):45-9
The American Journal of dermatopathology 2013 Feb;35(1):45-9
MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.
Alvelos MI, Vinagre J, Fonseca E, Barbosa E, Teixeira-Gomes J, Sobrinho-Simões M, Soares P
European journal of endocrinology 2013 Feb;168(2):119-28
European journal of endocrinology 2013 Feb;168(2):119-28
Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.
Liu W, Luo Y, Dunn JH, Norris DA, Dinarello CA, Fujita M
The Journal of investigative dermatology 2013 Feb;133(2):518-27
The Journal of investigative dermatology 2013 Feb;133(2):518-27
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.
Wang S, Bates J, Li X, Schanz S, Chandler-Militello D, Levine C, Maherali N, Studer L, Hochedlinger K, Windrem M, Goldman SA
Cell stem cell 2013 Feb 7;12(2):252-64
Cell stem cell 2013 Feb 7;12(2):252-64
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Atwood SX, Li M, Lee A, Tang JY, Oro AE
Nature 2013 Feb 28;494(7438):484-8
Nature 2013 Feb 28;494(7438):484-8
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.
Bressenot A, Pooya S, Bossenmeyer-Pourie C, Gauchotte G, Germain A, Chevaux JB, Coste F, Vignaud JM, Guéant JL, Peyrin-Biroulet L
The British journal of nutrition 2013 Feb 28;109(4):667-77
The British journal of nutrition 2013 Feb 28;109(4):667-77
eIF4F suppression in breast cancer affects maintenance and progression.
Nasr Z, Robert F, Porco JA Jr, Muller WJ, Pelletier J
Oncogene 2013 Feb 14;32(7):861-71
Oncogene 2013 Feb 14;32(7):861-71
Local insulin application on the carotid artery inhibits neointima formation.
Chiang S, Breen DM, Guo J, Mori Y, Giacca A
Canadian journal of physiology and pharmacology 2013 Dec;91(12):1086-94
Canadian journal of physiology and pharmacology 2013 Dec;91(12):1086-94
In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer.
Bentzien F, Zuzow M, Heald N, Gibson A, Shi Y, Goon L, Yu P, Engst S, Zhang W, Huang D, Zhao L, Vysotskaia V, Chu F, Bautista R, Cancilla B, Lamb P, Joly AH, Yakes FM
Thyroid : official journal of the American Thyroid Association 2013 Dec;23(12):1569-77
Thyroid : official journal of the American Thyroid Association 2013 Dec;23(12):1569-77
Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.
Ogawa K, Saeki N, Igura Y, Hayashi Y
Histochemistry and cell biology 2013 Dec;140(6):659-75
Histochemistry and cell biology 2013 Dec;140(6):659-75
PTEN loss mitigates the response of medulloblastoma to Hedgehog pathway inhibition.
Metcalfe C, Alicke B, Crow A, Lamoureux M, Dijkgraaf GJ, Peale F, Gould SE, de Sauvage FJ
Cancer research 2013 Dec 1;73(23):7034-42
Cancer research 2013 Dec 1;73(23):7034-42
Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice.
Losi P, Briganti E, Errico C, Lisella A, Sanguinetti E, Chiellini F, Soldani G
Acta biomaterialia 2013 Aug;9(8):7814-21
Acta biomaterialia 2013 Aug;9(8):7814-21
Systemic regulation of the age-related decline of pancreatic β-cell replication.
Salpeter SJ, Khalaileh A, Weinberg-Corem N, Ziv O, Glaser B, Dor Y
Diabetes 2013 Aug;62(8):2843-8
Diabetes 2013 Aug;62(8):2843-8
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Yan SB, Peek VL, Ajamie R, Buchanan SG, Graff JR, Heidler SA, Hui YH, Huss KL, Konicek BW, Manro JR, Shih C, Stewart JA, Stewart TR, Stout SL, Uhlik MT, Um SL, Wang Y, Wu W, Yan L, Yang WJ, Zhong B, Walgren RA
Investigational new drugs 2013 Aug;31(4):833-44
Investigational new drugs 2013 Aug;31(4):833-44
K5/K14-positive cells contribute to salivary gland-like breast tumors with myoepithelial differentiation.
Boecker W, Stenman G, Loening T, Andersson MK, Bankfalvi A, von Holstein S, Heegaard S, Lange A, Berg T, Samoilova V, Tiemann K, Buchwalow I
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Aug;26(8):1086-100
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Aug;26(8):1086-100
Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.
Kim WG, Park JW, Willingham MC, Cheng SY
Endocrinology 2013 Aug;154(8):2936-47
Endocrinology 2013 Aug;154(8):2936-47
Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models.
Xu S, Li S, Guo Z, Luo J, Ellis MJ, Ma CX
Molecular cancer therapeutics 2013 Aug;12(8):1665-75
Molecular cancer therapeutics 2013 Aug;12(8):1665-75
Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice.
Yao Y, Liu S, Wang Y, Yuan W, Ding X, Cheng T, Shen Q, Gu J
Neuroscience letters 2013 Aug 26;548:84-9
Neuroscience letters 2013 Aug 26;548:84-9
Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.
Oikawa T, Nakamura A, Onishi N, Yamada T, Matsuo K, Saya H
Cancer research 2013 Aug 15;73(16):5100-9
Cancer research 2013 Aug 15;73(16):5100-9
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y
Cancer cell 2013 Aug 12;24(2):242-56
Cancer cell 2013 Aug 12;24(2):242-56
Combination therapy of cilengitide with belotecan against experimental glioblastoma.
Kim YH, Lee JK, Kim B, DeWitt JP, Lee JE, Han JH, Kim SK, Oh CW, Kim CY
International journal of cancer 2013 Aug 1;133(3):749-56
International journal of cancer 2013 Aug 1;133(3):749-56
Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.
Defalco T, Saraswathula A, Briot A, Iruela-Arispe ML, Capel B
Biology of reproduction 2013 Apr;88(4):91
Biology of reproduction 2013 Apr;88(4):91
The PPARγ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.
Grommes C, Karlo JC, Caprariello A, Blankenship D, Dechant A, Landreth GE
Cancer chemotherapy and pharmacology 2013 Apr;71(4):929-36
Cancer chemotherapy and pharmacology 2013 Apr;71(4):929-36
Adenovirus-mediated interferon-γ gene therapy induced human pancreatic carcinoma Capan-2 cell apoptosis in vitro and in vivo.
Xie FJ, Zhao P, Zhang YP, Liu FY, Nie XL, Zhu YH, Yu XM, Zheng QQ, Mao WM, Lu HY, Wei H, Huang W
Anatomical record (Hoboken, N.J. : 2007) 2013 Apr;296(4):604-10
Anatomical record (Hoboken, N.J. : 2007) 2013 Apr;296(4):604-10
Specimen quality evaluation in Canadian biobanks participating in the COEUR repository.
Le Page C, Köbel M, de Ladurantaye M, Rahimi K, Madore J, Babinszky S, Bachvarov DR, Bachvarova M, Beauchamp MC, Cass CE, Chadwick D, Colleen C, Damaraju S, Dufour J, Gotlieb WH, Kalloger SE, Portelance L, McAlpine JN, Matte I, Piché A, Shaw P, Roehrl MH, Vanderhyden BC, Watson PH, Huntsman DG, Provencher DM, Mes-Masson AM
Biopreservation and biobanking 2013 Apr;11(2):83-93
Biopreservation and biobanking 2013 Apr;11(2):83-93
Hepatic regeneration and functional recovery following partial liver resection in an experimental model of hepatic steatosis treated with omega-3 fatty acids.
Marsman HA, de Graaf W, Heger M, van Golen RF, Ten Kate FJ, Bennink R, van Gulik TM
The British journal of surgery 2013 Apr;100(5):674-83
The British journal of surgery 2013 Apr;100(5):674-83
Proliferation and cell cycle dynamics in the developing stellate ganglion.
Gonsalvez DG, Cane KN, Landman KA, Enomoto H, Young HM, Anderson CR
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Apr 3;33(14):5969-79
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Apr 3;33(14):5969-79
Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis.
Akbay EA, Peña CG, Ruder D, Michel JA, Nakada Y, Pathak S, Multani AS, Chang S, Castrillon DH
Oncogene 2013 Apr 25;32(17):2211-9
Oncogene 2013 Apr 25;32(17):2211-9
Effects of steroid hormones on differentiated glandular epithelial and stromal cells in a three dimensional cell culture model of the canine endometrium.
Bartel C, Tichy A, Schoenkypl S, Aurich C, Walter I
BMC veterinary research 2013 Apr 24;9:86
BMC veterinary research 2013 Apr 24;9:86
Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.
Radhakrishnan P, Bryant VC, Blowers EC, Rajule RN, Gautam N, Anwar MM, Mohr AM, Grandgenett PM, Bunt SK, Arnst JL, Lele SM, Alnouti Y, Hollingsworth MA, Natarajan A
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2025-35
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2025-35
Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution.
Le Guillou S, Sdassi N, Laubier J, Passet B, Vilotte M, Castille J, Laloë D, Polyte J, Bouet S, Jaffrézic F, Cribiu EP, Vilotte JL, Le Provost F
PloS one 2012;7(9):e45727
PloS one 2012;7(9):e45727
Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.
Sui Y, Horne MK, Stanić D
PloS one 2012;7(2):e31549
PloS one 2012;7(2):e31549
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.
Cawthorn TR, Moreno JC, Dharsee M, Tran-Thanh D, Ackloo S, Zhu PH, Sardana G, Chen J, Kupchak P, Jacks LM, Miller NA, Youngson BJ, Iakovlev V, Guidos CJ, Vallis KA, Evans KR, McCready D, Leong WL, Done SJ
PloS one 2012;7(2):e30992
PloS one 2012;7(2):e30992
Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
Saqui-Salces M, Covés-Datson E, Veniaminova NA, Waghray M, Syu LJ, Dlugosz AA, Merchant JL
PloS one 2012;7(10):e48039
PloS one 2012;7(10):e48039
The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.
Méndez-Gómez HR, Vicario-Abejón C
PloS one 2012;7(1):e29799
PloS one 2012;7(1):e29799
An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.
Shah M, Huang D, Blick T, Connor A, Reiter LA, Hardink JR, Lynch CC, Waltham M, Thompson EW
PloS one 2012;7(1):e29615
PloS one 2012;7(1):e29615
Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression.
Choe Y, Pleasure SJ
Developmental neuroscience 2012;34(6):502-14
Developmental neuroscience 2012;34(6):502-14
Cauda equina paraganglioma with ependymoma-like histology: a case report.
Midi A, Yener AN, Sav A, Cubuk R
Turkish neurosurgery 2012;22(3):353-9
Turkish neurosurgery 2012;22(3):353-9
Fates of murine pluripotent stem cell-derived neural progenitors following transplantation into mouse cochleae.
Nishimura K, Nakagawa T, Sakamoto T, Ito J
Cell transplantation 2012;21(4):763-71
Cell transplantation 2012;21(4):763-71
A crucial role of bone morphogenetic protein signaling in the wound healing response in acute liver injury induced by carbon tetrachloride.
Oumi N, Taniguchi KA, Kanai AM, Yasunaga M, Nakanishi T, Sato K
International journal of hepatology 2012;2012:476820
International journal of hepatology 2012;2012:476820
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.
Anttonen T, Kirjavainen A, Belevich I, Laos M, Richardson WD, Jokitalo E, Brakebusch C, Pirvola U
Scientific reports 2012;2:978
Scientific reports 2012;2:978
Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence.
He X, Yang WC, Wen XY, Tang D, Xiao L, Han J, Yu B, Zhang W, Mei F
Cells, tissues, organs 2012;196(2):175-88
Cells, tissues, organs 2012;196(2):175-88
Oxidative stress gradient in a medium during human corneal organ culture.
Johnsen-Soriano S, Haug K, Arnal E, Peris-Martinez C, Moe MC, Romero FJ, Nicolaissen B
Molecular vision 2012;18:1604-8
Molecular vision 2012;18:1604-8
Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.
Alvarenga CA, Lopes JM, Vinagre J, Paravidino PI, Alvarenga M, Prando A, Castilho LN, Soares P, Billis A
Sao Paulo medical journal = Revista paulista de medicina 2012;130(1):57-60
Sao Paulo medical journal = Revista paulista de medicina 2012;130(1):57-60
Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.
Alvarenga CA, Lopes JM, Vinagre J, Paravidino PI, Alvarenga M, Prando A, Castilho LN, Soares P, Billis A
Sao Paulo medical journal = Revista paulista de medicina 2012;130(1):57-60
Sao Paulo medical journal = Revista paulista de medicina 2012;130(1):57-60
MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.
Xu CS, Zheng JY, Zhang HL, Zhao HD, Zhang J, Wu GQ, Wu L, Wang Q, Wang WZ, Zhang J
Asian Pacific journal of cancer prevention : APJCP 2012;13(7):3233-8
Asian Pacific journal of cancer prevention : APJCP 2012;13(7):3233-8
MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.
Xu CS, Zheng JY, Zhang HL, Zhao HD, Zhang J, Wu GQ, Wu L, Wang Q, Wang WZ, Zhang J
Asian Pacific journal of cancer prevention : APJCP 2012;13(7):3233-8
Asian Pacific journal of cancer prevention : APJCP 2012;13(7):3233-8
Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.
Goldshmit Y, Matteo R, Sztal T, Ellett F, Frisca F, Moreno K, Crombie D, Lieschke GJ, Currie PD, Sabbadini RA, Pébay A
The American journal of pathology 2012 Sep;181(3):978-92
The American journal of pathology 2012 Sep;181(3):978-92
Somatotroph pituitary adenoma with acromegaly and autosomal dominant polycystic kidney disease: SSTR5 polymorphism and PKD1 mutation.
Syro LV, Sundsbak JL, Scheithauer BW, Toledo RA, Camargo M, Heyer CM, Sekiya T, Uribe H, Escobar JI, Vasquez M, Rotondo F, Toledo SP, Kovacs K, Horvath E, Babovic-Vuksanovic D, Harris PC
Pituitary 2012 Sep;15(3):342-9
Pituitary 2012 Sep;15(3):342-9
Rgs19 regulates mouse palatal fusion by modulating cell proliferation and apoptosis in the MEE.
Sohn WJ, Ji YR, Kim HS, Gwon GJ, Chae YM, An CH, Park HD, Jung HS, Ryoo ZY, Lee S, Kim JY
Mechanisms of development 2012 Sep-Dec;129(9-12):244-54
Mechanisms of development 2012 Sep-Dec;129(9-12):244-54
WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.
Rogers HA, Sousa S, Salto C, Arenas E, Coyle B, Grundy RG
British journal of cancer 2012 Sep 25;107(7):1144-52
British journal of cancer 2012 Sep 25;107(7):1144-52
Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia.
Veniaminova NA, Hayes MM, Varney JM, Merchant JL
American journal of physiology. Gastrointestinal and liver physiology 2012 Sep 15;303(6):G752-64
American journal of physiology. Gastrointestinal and liver physiology 2012 Sep 15;303(6):G752-64
Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer.
Naushad SM, Pavani A, Rupasree Y, Divyya S, Deepti S, Digumarti RR, Gottumukkala SR, Prayaga A, Kutala VK
Molecular carcinogenesis 2012 Oct;51 Suppl 1:E32-41
Molecular carcinogenesis 2012 Oct;51 Suppl 1:E32-41
Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.
Pacal M, Bremner R
Developmental dynamics : an official publication of the American Association of Anatomists 2012 Oct;241(10):1525-44
Developmental dynamics : an official publication of the American Association of Anatomists 2012 Oct;241(10):1525-44
Testis development requires the repression of Wnt4 by Fgf signaling.
Jameson SA, Lin YT, Capel B
Developmental biology 2012 Oct 1;370(1):24-32
Developmental biology 2012 Oct 1;370(1):24-32
Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction.
Sahu RP, DaSilva SC, Rashid B, Martel KC, Jernigan D, Mehta SR, Mohamed DR, Rezania S, Bradish JR, Armstrong AB, Warren S, Konger RL
International journal of cancer 2012 Oct 1;131(7):E1055-66
International journal of cancer 2012 Oct 1;131(7):E1055-66
Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas.
Asmane I, Watkin E, Alberti L, Duc A, Marec-Berard P, Ray-Coquard I, Cassier P, Decouvelaere AV, Ranchère D, Kurtz JE, Bergerat JP, Blay JY
European journal of cancer (Oxford, England : 1990) 2012 Nov;48(16):3027-35
European journal of cancer (Oxford, England : 1990) 2012 Nov;48(16):3027-35
Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation.
Revskaya E, Chu P, Howell RC, Schweitzer AD, Bryan RA, Harris M, Gerfen G, Jiang Z, Jandl T, Kim K, Ting LM, Sellers RS, Dadachova E, Casadevall A
Cancer biotherapy & radiopharmaceuticals 2012 Nov;27(9):570-6
Cancer biotherapy & radiopharmaceuticals 2012 Nov;27(9):570-6
Radioimmunotherapy of fibroblast activation protein positive tumors by rapidly internalizing antibodies.
Fischer E, Chaitanya K, Wüest T, Wadle A, Scott AM, van den Broek M, Schibli R, Bauer S, Renner C
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Nov 15;18(22):6208-18
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Nov 15;18(22):6208-18
Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments.
Nguyen L, Fifis T, Malcontenti-Wilson C, Chan LS, Costa PN, Nikfarjam M, Muralidharan V, Christophi C
BMC cancer 2012 Nov 15;12:522
BMC cancer 2012 Nov 15;12:522
Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.
Jagielska A, Norman AL, Whyte G, Vliet KJ, Guck J, Franklin RJ
Stem cells and development 2012 Nov 1;21(16):2905-14
Stem cells and development 2012 Nov 1;21(16):2905-14
Activation of neural progenitor cells in human eyes with proliferative vitreoretinopathy.
Johnsen EO, Frøen RC, Albert R, Omdal BK, Sarang Z, Berta A, Nicolaissen B, Petrovski G, Moe MC
Experimental eye research 2012 May;98:28-36
Experimental eye research 2012 May;98:28-36
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity.
Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan YN, Jan LY
Journal of molecular medicine (Berlin, Germany) 2012 May;90(5):575-85
Journal of molecular medicine (Berlin, Germany) 2012 May;90(5):575-85
Is primary pulmonary meningioma a giant form of a meningothelial-like nodule? A case report and review of the literature.
Masago K, Hosada W, Sasaki E, Murakami Y, Sugano M, Nagasaka T, Yamada M, Yatabe Y
Case reports in oncology 2012 May;5(2):471-8
Case reports in oncology 2012 May;5(2):471-8
The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.
Lee CH, Mariño-Enriquez A, Ou W, Zhu M, Ali RH, Chiang S, Amant F, Gilks CB, van de Rijn M, Oliva E, Debiec-Rychter M, Dal Cin P, Fletcher JA, Nucci MR
The American journal of surgical pathology 2012 May;36(5):641-53
The American journal of surgical pathology 2012 May;36(5):641-53
Increased FDG uptake in breast cancer is associated with prognostic factors.
Sanli Y, Kuyumcu S, Ozkan ZG, Işik G, Karanlik H, Guzelbey B, Turkmen C, Ozel S, Yavuz E, Mudun A
Annals of nuclear medicine 2012 May;26(4):345-50
Annals of nuclear medicine 2012 May;26(4):345-50
Bimodal effect of retinoic acid on melanocyte differentiation identified by time-dependent analysis.
Inoue Y, Hasegawa S, Yamada T, Date Y, Mizutani H, Nakata S, Matsunaga K, Akamatsu H
Pigment cell & melanoma research 2012 May;25(3):299-311
Pigment cell & melanoma research 2012 May;25(3):299-311
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.
Wan M, Huang W, Kute TE, Miller LD, Zhang Q, Hatcher H, Wang J, Stovall DB, Russell GB, Cao PD, Deng Z, Wang W, Zhang Q, Lei M, Torti SV, Akman SA, Sui G
The American journal of pathology 2012 May;180(5):2120-33
The American journal of pathology 2012 May;180(5):2120-33
Targeting colorectal cancer stem cells with inducible caspase-9.
Kemper K, Rodermond H, Colak S, Grandela C, Medema JP
Apoptosis : an international journal on programmed cell death 2012 May;17(5):528-37
Apoptosis : an international journal on programmed cell death 2012 May;17(5):528-37
Functional consequences of human airway smooth muscle phenotype plasticity.
Dekkers BG, Bos IS, Zaagsma J, Meurs H
British journal of pharmacology 2012 May;166(1):359-67
British journal of pharmacology 2012 May;166(1):359-67
IL-12 and IL-23 affect photocarcinogenesis differently.
Jantschitsch C, Weichenthal M, Proksch E, Schwarz T, Schwarz A
The Journal of investigative dermatology 2012 May;132(5):1479-86
The Journal of investigative dermatology 2012 May;132(5):1479-86
Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase.
Hiyoshi H, Abdelhady S, Segerström L, Sveinbjörnsson B, Nuriya M, Lundgren TK, Desfrere L, Miyakawa A, Yasui M, Kogner P, Johnsen JI, Andäng M, Uhlén P
British journal of cancer 2012 May 22;106(11):1807-15
British journal of cancer 2012 May 22;106(11):1807-15
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.
Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, Walz G, Huber TB
Autophagy 2012 May 1;8(5):826-37
Autophagy 2012 May 1;8(5):826-37
PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.
Lan R, Geng H, Polichnowski AJ, Singha PK, Saikumar P, McEwen DG, Griffin KA, Koesters R, Weinberg JM, Bidani AK, Kriz W, Venkatachalam MA
American journal of physiology. Renal physiology 2012 May 1;302(9):F1210-23
American journal of physiology. Renal physiology 2012 May 1;302(9):F1210-23
Expression and activation of EphA4 in the human brain after traumatic injury.
Frugier T, Conquest A, McLean C, Currie P, Moses D, Goldshmit Y
Journal of neuropathology and experimental neurology 2012 Mar;71(3):242-50
Journal of neuropathology and experimental neurology 2012 Mar;71(3):242-50
Early onset of endothelial cell proliferation in coronary thrombi of patients with an acute myocardial infarction: implications for plaque healing.
Li X, Kramer MC, VAN DER Loos CM, Ploegmakers HJ, DE Boer OJ, Koch KT, Tijssen JG, DE Winter RJ, VAN DER Wal AC
Journal of thrombosis and haemostasis : JTH 2012 Mar;10(3):466-73
Journal of thrombosis and haemostasis : JTH 2012 Mar;10(3):466-73
Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice.
Friedrich S, Schwabe K, Klein R, Krusche CA, Krauss JK, Nakamura M
Journal of neuroscience methods 2012 Mar 30;205(1):1-9
Journal of neuroscience methods 2012 Mar 30;205(1):1-9
De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy.
Zhang J, Hansen KM, Pippin JW, Chang AM, Taniguchi Y, Krofft RD, Pickering SG, Liu ZH, Abrass CK, Shankland SJ
American journal of physiology. Renal physiology 2012 Mar 1;302(5):F571-80
American journal of physiology. Renal physiology 2012 Mar 1;302(5):F571-80
The effects of intrauterine growth restriction and antenatal glucocorticoids on ovine fetal lung development.
Sutherland AE, Crossley KJ, Allison BJ, Jenkin G, Wallace EM, Miller SL
Pediatric research 2012 Jun;71(6):689-96
Pediatric research 2012 Jun;71(6):689-96
Effect of staged ovariectomy on measures of mammary growth and development in prepubertal dairy heifers.
Velayudhan BT, Huderson BP, McGilliard ML, Jiang H, Ellis SE, Akers RM
Animal : an international journal of animal bioscience 2012 Jun;6(6):941-51
Animal : an international journal of animal bioscience 2012 Jun;6(6):941-51
Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
Dagıstan Y, Karaca I, Bozkurt ER, Ozar E, Yagmurlu K, Toklu A, Bilir A
Acta cirurgica brasileira 2012 Jun;27(6):383-7
Acta cirurgica brasileira 2012 Jun;27(6):383-7
HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients.
Seki H, Hayashida T, Jinno H, Hirose S, Sakata M, Takahashi M, Maheswaran S, Mukai M, Kitagawa Y
Annals of surgical oncology 2012 Jun;19(6):1831-40
Annals of surgical oncology 2012 Jun;19(6):1831-40
Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.
Joshi A, Wang H, Jiang G, Douglas W, Chan JS, Korach KS, Ellenson LH
The American journal of pathology 2012 Jun;180(6):2536-47
The American journal of pathology 2012 Jun;180(6):2536-47
YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.
Zhi X, Zhao D, Zhou Z, Liu R, Chen C
The American journal of pathology 2012 Jun;180(6):2452-61
The American journal of pathology 2012 Jun;180(6):2452-61
Pigmented paraganglioma of the kidney: a case report.
Zhao L, Luo J, Zhang H, Da J
Diagnostic pathology 2012 Jun 28;7:77
Diagnostic pathology 2012 Jun 28;7:77
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Shan W, Akinfenwa PY, Savannah KB, Kolomeyevskaya N, Laucirica R, Thomas DG, Odunsi K, Creighton CJ, Lev DC, Anderson ML
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Jun 15;18(12):3352-65
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Jun 15;18(12):3352-65
Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.
Thomas C, Wafa LA, Lamoureux F, Cheng H, Fazli L, Gleave ME, Rennie PS
The Prostate 2012 Jun 1;72(8):875-85
The Prostate 2012 Jun 1;72(8):875-85
Effects of acrylamide exposure on serum hormones, gene expression, cell proliferation, and histopathology in male reproductive tissues of Fischer 344 rats.
Camacho L, Latendresse JR, Muskhelishvili L, Patton R, Bowyer JF, Thomas M, Doerge DR
Toxicology letters 2012 Jun 1;211(2):135-43
Toxicology letters 2012 Jun 1;211(2):135-43
Collective action of hematopoietic cell subsets mediates anti-IL10R1 and CpG tumor immunity.
Chou MY, Austin CD, Kim JM
Cancer immunology, immunotherapy : CII 2012 Jul;61(7):1055-64
Cancer immunology, immunotherapy : CII 2012 Jul;61(7):1055-64
Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice.
Quan L, Dittmar A, Zhou Y, Hutson A, Stassen AP, Demant P
Genes, chromosomes & cancer 2012 Jul;51(7):631-43
Genes, chromosomes & cancer 2012 Jul;51(7):631-43
The adult pituitary shows stem/progenitor cell activation in response to injury and is capable of regeneration.
Fu Q, Gremeaux L, Luque RM, Liekens D, Chen J, Buch T, Waisman A, Kineman R, Vankelecom H
Endocrinology 2012 Jul;153(7):3224-35
Endocrinology 2012 Jul;153(7):3224-35
No harmful effect of mycophenolate mofetil on liver regeneration: an experimental study.
Demiray M, Kucuk HF, Yildirim M, Barisik NO
Transplantation proceedings 2012 Jul-Aug;44(6):1743-6
Transplantation proceedings 2012 Jul-Aug;44(6):1743-6
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.
Du Y, Kong G, You X, Zhang S, Zhang T, Gao Y, Ye L, Zhang X
The Journal of biological chemistry 2012 Jul 27;287(31):26302-11
The Journal of biological chemistry 2012 Jul 27;287(31):26302-11
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
Zhao L, Chen CN, Hajji N, Oliver E, Cotroneo E, Wharton J, Wang D, Li M, McKinsey TA, Stenmark KR, Wilkins MR
Circulation 2012 Jul 24;126(4):455-67
Circulation 2012 Jul 24;126(4):455-67
Nanostructured porous silicon micropatterns as a tool for substrate-conditioned cell research.
Punzón-Quijorna E, Sánchez-Vaquero V, Muñoz-Noval A, Pérez-Roldán MJ, Martín-Palma RJ, Rossi F, Climent-Font A, Manso-Silván M, Ruiz JP, Torres-Costa V
Nanoscale research letters 2012 Jul 16;7(1):396
Nanoscale research letters 2012 Jul 16;7(1):396
Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.
Feng S, Shao L, Yu W, Gavine P, Ittmann M
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Jul 15;18(14):3880-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Jul 15;18(14):3880-8
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
Zeng M, Southern PJ, Reilly CS, Beilman GJ, Chipman JG, Schacker TW, Haase AT
PLoS pathogens 2012 Jan;8(1):e1002437
PLoS pathogens 2012 Jan;8(1):e1002437
Primary pure squamous cell carcinoma of the thyroid: report and histogenic consideration of a case involving a BRAF mutation.
Ko YS, Hwang TS, Han HS, Lim SD, Kim WS, Oh SY
Pathology international 2012 Jan;62(1):43-8
Pathology international 2012 Jan;62(1):43-8
Early changes in carcinogenesis of colorectal adenomas.
Toru S, Bilezikçi B
The West Indian medical journal 2012 Jan;61(1):10-6
The West Indian medical journal 2012 Jan;61(1):10-6
Early changes in carcinogenesis of colorectal adenomas.
Toru S, Bilezikçi B
The West Indian medical journal 2012 Jan;61(1):10-6
The West Indian medical journal 2012 Jan;61(1):10-6
Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.
Bergmeister H, Grasl C, Walter I, Plasenzotti R, Stoiber M, Schreiber C, Losert U, Weigel G, Schima H
Artificial organs 2012 Jan;36(1):54-61
Artificial organs 2012 Jan;36(1):54-61
Cell signaling pathways associated with a reduction in mammary cancer burden by dietary common bean (Phaseolus vulgaris L.).
Thompson MD, Mensack MM, Jiang W, Zhu Z, Lewis MR, McGinley JN, Brick MA, Thompson HJ
Carcinogenesis 2012 Jan;33(1):226-32
Carcinogenesis 2012 Jan;33(1):226-32
The prognostic value of Skp2 expression in Egyptian diffuse large B-cell lymphoma.
Abdou AG, Asaad NY, Abd El-Wahed MM, Samaka RM, Allah MS
Applied immunohistochemistry & molecular morphology : AIMM 2012 Jan;20(1):47-55
Applied immunohistochemistry & molecular morphology : AIMM 2012 Jan;20(1):47-55
Quantitative assessment of liver function after ischemia-reperfusion injury and partial hepatectomy in rats.
de Graaf W, Heger M, Spruijt O, Maas A, de Bruin K, Hoekstra R, Bennink RJ, van Gulik TM
The Journal of surgical research 2012 Jan;172(1):85-94
The Journal of surgical research 2012 Jan;172(1):85-94
Failure of delayed intravenous administration of bone marrow stromal cells after traumatic brain injury.
Bonilla C, Zurita M, Otero L, Aguayo C, Rico MA, Rodríguez A, Vaquero J
Journal of neurotrauma 2012 Jan 20;29(2):394-400
Journal of neurotrauma 2012 Jan 20;29(2):394-400
Insights antifibrotic mechanism of methyl palmitate: impact on nuclear factor kappa B and proinflammatory cytokines.
Mantawy EM, Tadros MG, Awad AS, Hassan DA, El-Demerdash E
Toxicology and applied pharmacology 2012 Jan 1;258(1):134-44
Toxicology and applied pharmacology 2012 Jan 1;258(1):134-44
Honey as a substitute for formalin?
Ozkan N, Salva E, Cakalağaoğlu F, Tüzüner B
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2012 Feb;87(2):148-53
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2012 Feb;87(2):148-53
Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.
Mork L, Maatouk DM, McMahon JA, Guo JJ, Zhang P, McMahon AP, Capel B
Biology of reproduction 2012 Feb;86(2):37
Biology of reproduction 2012 Feb;86(2):37
Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model.
Ruf MT, Schütte D, Chauffour A, Jarlier V, Ji B, Pluschke G
Antimicrobial agents and chemotherapy 2012 Feb;56(2):687-96
Antimicrobial agents and chemotherapy 2012 Feb;56(2):687-96
Increased adult hippocampal neurogenesis and abnormal migration of adult-born granule neurons is associated with hippocampal-specific cognitive deficits in phospholipase C-β1 knockout mice.
Manning EE, Ransome MI, Burrows EL, Hannan AJ
Hippocampus 2012 Feb;22(2):309-19
Hippocampus 2012 Feb;22(2):309-19
Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation.
Low J, Blosser W, Dowless M, Ricci-Vitiani L, Pallini R, de Maria R, Stancato L
Journal of biomolecular screening 2012 Feb;17(2):152-62
Journal of biomolecular screening 2012 Feb;17(2):152-62
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC
Development (Cambridge, England) 2012 Feb;139(3):488-97
Development (Cambridge, England) 2012 Feb;139(3):488-97
Evaluation of apoptosis along with BCL-2 and Ki-67 expression in patients with intestinal metaplasia.
Erkan G, Gonul II, Kandilci U, Dursun A
Pathology, research and practice 2012 Feb 15;208(2):89-93
Pathology, research and practice 2012 Feb 15;208(2):89-93
An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells.
Houben R, Adam C, Baeurle A, Hesbacher S, Grimm J, Angermeyer S, Henzel K, Hauser S, Elling R, Bröcker EB, Gaubatz S, Becker JC, Schrama D
International journal of cancer 2012 Feb 15;130(4):847-56
International journal of cancer 2012 Feb 15;130(4):847-56
Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo.
Xia W, Wang P, Lin C, Li Z, Gao X, Wang G, Zhao X
Journal of controlled release : official journal of the Controlled Release Society 2012 Feb 10;157(3):427-36
Journal of controlled release : official journal of the Controlled Release Society 2012 Feb 10;157(3):427-36
Differential function of NBS1 and ATR in neurogenesis.
Zhou Z, Bruhn C, Wang ZQ
DNA repair 2012 Feb 1;11(2):210-21
DNA repair 2012 Feb 1;11(2):210-21
Evidence of mTOR Activation by an AKT-Independent Mechanism Provides Support for the Combined Treatment of PTEN-Deficient Prostate Tumors with mTOR and AKT Inhibitors.
Zhang W, Haines BB, Efferson C, Zhu J, Ware C, Kunii K, Tammam J, Angagaw M, Hinton MC, Keilhack H, Paweletz CP, Zhang T, Winter C, Sathyanarayanan S, Cheng J, Zawel L, Fawell S, Gilliland G, Majumder PK
Translational oncology 2012 Dec;5(6):422-9
Translational oncology 2012 Dec;5(6):422-9
BCL10 down-regulation in peripheral T-cell lymphomas.
Rossi M, Agostinelli C, Righi S, Sabattini E, Bacci F, Gazzola A, Pileri SA, Piccaluga PP
Human pathology 2012 Dec;43(12):2266-73
Human pathology 2012 Dec;43(12):2266-73
Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors.
Schmidt-Strassburger U, Schips TG, Maier HJ, Kloiber K, Mannella F, Braunstein KE, Holzmann K, Ushmorov A, Liebau S, Boeckers TM, Wirth T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Dec;26(12):4990-5001
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Dec;26(12):4990-5001
Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis.
Quattrone A, Dewaele B, Wozniak A, Bauters M, Vanspauwen V, Floris G, Schöffski P, Chibon F, Coindre JM, Sciot R, Debiec-Rychter M
The Journal of pathology 2012 Dec;228(4):565-74
The Journal of pathology 2012 Dec;228(4):565-74
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, Samuelson LC, Dlugosz AA
The American journal of pathology 2012 Dec;181(6):2114-25
The American journal of pathology 2012 Dec;181(6):2114-25
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.
Li J, Jiang TX, Hughes MW, Wu P, Yu J, Widelitz RB, Fan G, Chuong CM
The Journal of investigative dermatology 2012 Dec;132(12):2681-90
The Journal of investigative dermatology 2012 Dec;132(12):2681-90
Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues.
Neumeister VM, Anagnostou V, Siddiqui S, England AM, Zarrella ER, Vassilakopoulou M, Parisi F, Kluger Y, Hicks DG, Rimm DL
Journal of the National Cancer Institute 2012 Dec 5;104(23):1815-24
Journal of the National Cancer Institute 2012 Dec 5;104(23):1815-24
Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals.
Lühr I, Friedl A, Overath T, Tholey A, Kunze T, Hilpert F, Sebens S, Arnold N, Rösel F, Oberg HH, Maass N, Mundhenke C, Jonat W, Bauer M
Cancer letters 2012 Dec 28;325(2):175-88
Cancer letters 2012 Dec 28;325(2):175-88
Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors.
Shao L, Tekedereli I, Wang J, Yuca E, Tsang S, Sood A, Lopez-Berestein G, Ozpolat B, Ittmann M
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Dec 15;18(24):6648-57
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Dec 15;18(24):6648-57
Regenerative capacity of the adult pituitary: multiple mechanisms of lactotrope restoration after transgenic ablation.
Fu Q, Vankelecom H
Stem cells and development 2012 Dec 10;21(18):3245-57
Stem cells and development 2012 Dec 10;21(18):3245-57
Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx).
Chaudary N, Pintilie M, Schwock J, Dhani N, Clarke B, Milosevic M, Fyles A, Hill RP
Cancers 2012 Aug 29;4(3):821-45
Cancers 2012 Aug 29;4(3):821-45
Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids.
Jiang W, Zhu Z, McGinley JN, El Bayoumy K, Manni A, Thompson HJ
Cancer research 2012 Aug 1;72(15):3795-806
Cancer research 2012 Aug 1;72(15):3795-806
Intermediate progenitors are increased by lengthening of the cell cycle through calcium signaling and p53 expression in human neural progenitors.
García-García E, Pino-Barrio MJ, López-Medina L, Martínez-Serrano A
Molecular biology of the cell 2012 Apr;23(7):1167-80
Molecular biology of the cell 2012 Apr;23(7):1167-80
Antitumor effects of cis-urocanic acid on experimental urothelial cell carcinoma of the bladder.
Arentsen HC, Jansen CF, Hulsbergen-van de Kaa CA, Laihia JK, Pylkkänen L, Leino L, Oosterwijk E, Witjes JA
The Journal of urology 2012 Apr;187(4):1445-9
The Journal of urology 2012 Apr;187(4):1445-9
Overexpression of cathepsin S induces chronic atopic dermatitis in mice.
Kim N, Bae KB, Kim MO, Yu DH, Kim HJ, Yuh HS, Ji YR, Park SJ, Kim S, Son KH, Park SJ, Yoon D, Lee DS, Lee S, Lee HS, Kim TY, Ryoo ZY
The Journal of investigative dermatology 2012 Apr;132(4):1169-76
The Journal of investigative dermatology 2012 Apr;132(4):1169-76
KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer.
Anbalagan M, Carrier L, Glodowski S, Hangauer D, Shan B, Rowan BG
Breast cancer research and treatment 2012 Apr;132(2):391-409
Breast cancer research and treatment 2012 Apr;132(2):391-409
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
Yin WH, Li J, Chan JK
Diagnostic pathology 2012 Apr 12;7:39
Diagnostic pathology 2012 Apr 12;7:39
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
Lepore AC, O'Donnell J, Kim AS, Williams T, Tuteja A, Rao MS, Kelley LL, Campanelli JT, Maragakis NJ
PloS one 2011;6(10):e25968
PloS one 2011;6(10):e25968
Tumor Vascular Morphology Undergoes Dramatic Changes during Outgrowth of B16 Melanoma While Proangiogenic Gene Expression Remains Unchanged.
Langenkamp E, Vom Hagen FM, Zwiers PJ, Moorlag HE, Schouten JP, Hammes HP, Gouw AS, Molema G
ISRN oncology 2011;2011:409308
ISRN oncology 2011;2011:409308
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.
Li S, Thangapazham RL, Wang JA, Rajesh S, Kao TC, Sperling L, Moss J, Darling TN
Nature communications 2011;2:235
Nature communications 2011;2:235
Early cyst growth is associated with the increased nuclear expression of cyclin D1/Rb protein in an autosomal-recessive polycystic kidney disease rat model.
Schwensen KG, Burgess JS, Graf NS, Alexander SI, Harris DC, Phillips JK, Rangan GK
Nephron. Experimental nephrology 2011;117(4):e93-103
Nephron. Experimental nephrology 2011;117(4):e93-103
Cytogenetic analysis of a malignant triton tumour by comparative genomic hybridization (CGH) and review of the literature.
Koutsimpelas D, Brieger J, Heinrich U, Torzewski M, Sommer C, Mann WJ
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2011 Sep;268(9):1391-6
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2011 Sep;268(9):1391-6
Kidney spheroids recapitulate tubular organoids leading to enhanced tubulogenic potency of human kidney-derived cells.
Buzhor E, Harari-Steinberg O, Omer D, Metsuyanim S, Jacob-Hirsch J, Noiman T, Dotan Z, Goldstein RS, Dekel B
Tissue engineering. Part A 2011 Sep;17(17-18):2305-19
Tissue engineering. Part A 2011 Sep;17(17-18):2305-19
Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth by increasing apoptosis.
Teng BP, Heffler MD, Lai EC, Zhao YL, LeVea CM, Golubovskaya VM, Bullarddunn KM
Anti-cancer agents in medicinal chemistry 2011 Sep;11(7):620-8
Anti-cancer agents in medicinal chemistry 2011 Sep;11(7):620-8
Restrictions that control herpes simplex virus type 1 infection in mouse brain ex vivo.
Cohen M, Braun E, Tsalenchuck Y, Panet A, Steiner I
The Journal of general virology 2011 Oct;92(Pt 10):2383-2393
The Journal of general virology 2011 Oct;92(Pt 10):2383-2393
Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.
Oliver JR, Kushwah R, Wu J, Pan J, Cutz E, Yeger H, Waddell TK, Hu J
Laboratory investigation; a journal of technical methods and pathology 2011 Oct;91(10):1514-29
Laboratory investigation; a journal of technical methods and pathology 2011 Oct;91(10):1514-29
Molecular phenotypes of matched in situ and invasive components of breast carcinomas.
Martins D, Sousa B, Lopes N, Gomes M, Veronese L, Albergaria A, Paredes J, Schmitt F
Human pathology 2011 Oct;42(10):1438-46
Human pathology 2011 Oct;42(10):1438-46
Influence of heparan sulfate chains in proteoglycan at the dermal-epidermal junction on epidermal homeostasis.
Iriyama S, Hiruma T, Tsunenaga M, Amano S
Experimental dermatology 2011 Oct;20(10):810-4
Experimental dermatology 2011 Oct;20(10):810-4
Expression of fascin protein and mRNA in the KB carcinoma cell line following treatment with doxorubicin.
Alaeddini M, Fouladdel S, Etemad-Moghadam S, Azizi E
Journal of cancer research and therapeutics 2011 Oct-Dec;7(4):427-32
Journal of cancer research and therapeutics 2011 Oct-Dec;7(4):427-32
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L Jr, Singh H, Ouyang W, Pappu R
Nature immunology 2011 Oct 12;12(12):1159-66
Nature immunology 2011 Oct 12;12(12):1159-66
Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis.
Sörensen I, Susnik N, Inhester T, Degen JL, Melk A, Haller H, Schmitt R
Kidney international 2011 Nov;80(10):1035-44
Kidney international 2011 Nov;80(10):1035-44
Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas.
Ishino H, Hara Y, Takekoshi S, Teshima T, Teramoto A, Osamura RY, Tagawa M
Domestic animal endocrinology 2011 Nov;41(4):207-13
Domestic animal endocrinology 2011 Nov;41(4):207-13
Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival.
Ege CB, Akbulut M, Zekioğlu O, Ozdemir N
Archives of gynecology and obstetrics 2011 Nov;284(5):1231-9
Archives of gynecology and obstetrics 2011 Nov;284(5):1231-9
Endothelium-coated tumor clusters are associated with poor prognosis and micrometastasis of hepatocellular carcinoma after resection.
Ding T, Xu J, Zhang Y, Guo RP, Wu WC, Zhang SD, Qian CN, Zheng L
Cancer 2011 Nov 1;117(21):4878-89
Cancer 2011 Nov 1;117(21):4878-89
High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.
Ognibene M, Barbieri O, Vanni C, Mastracci L, Astigiano S, Emionite L, Salani B, Fedele M, Resaz R, Tenca C, Fais F, Sabatini F, De Santanna A, Altruda F, Varesio L, Hirsch E, Eva A
Journal of molecular medicine (Berlin, Germany) 2011 May;89(5):493-504
Journal of molecular medicine (Berlin, Germany) 2011 May;89(5):493-504
Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.
Vandewoestyne ML, Pede VC, Lambein KY, Dhaenens MF, Offner FC, Praet MM, Philippé JJ, Kipps TJ, Deforce DL
Leukemia 2011 May;25(5):883-8
Leukemia 2011 May;25(5):883-8
Development of skin-humanized mouse models of pachyonychia congenita.
García M, Larcher F, Hickerson RP, Baselga E, Leachman SA, Kaspar RL, Del Rio M
The Journal of investigative dermatology 2011 May;131(5):1053-60
The Journal of investigative dermatology 2011 May;131(5):1053-60
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M, Dlugosz AA
The Journal of clinical investigation 2011 May;121(5):1768-81
The Journal of clinical investigation 2011 May;121(5):1768-81
Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies.
Joshua AM, Shen E, Yoshimoto M, Marrano P, Zielenska M, Evans AJ, Van der Kwast T, Squire JA
The Prostate 2011 May 15;71(7):778-90
The Prostate 2011 May 15;71(7):778-90
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM
Nature 2011 May 15;474(7351):403-6
Nature 2011 May 15;474(7351):403-6
Endogenous Myc maintains the tumor microenvironment.
Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L
Genes & development 2011 May 1;25(9):907-16
Genes & development 2011 May 1;25(9):907-16
A comparative immunohistochemical analysis of COX-2, p53, and Ki-67 expression in keratocystic odontogenic tumors.
Mendes RA, Carvalho JF, van der Waal I
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Mar;111(3):333-9
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Mar;111(3):333-9
Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model.
Yuen JS, Sim MY, Siml HG, Chong TW, Lau WK, Cheng CW, Huynh H
British journal of cancer 2011 Mar 15;104(6):941-7
British journal of cancer 2011 Mar 15;104(6):941-7
The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model.
Sampson ER, Martin BA, Morris AE, Xie C, Schwarz EM, O'Keefe RJ, Rosier RN
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Jun;26(6):1283-94
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Jun;26(6):1283-94
Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.
Ager EI, Wen SW, Chan J, Chong WW, Neo JH, Christophi C
BMC cancer 2011 Jun 26;11:274
BMC cancer 2011 Jun 26;11:274
Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells.
Damelin M, Geles KG, Follettie MT, Yuan P, Baxter M, Golas J, DiJoseph JF, Karnoub M, Huang S, Diesl V, Behrens C, Choe SE, Rios C, Gruzas J, Sridharan L, Dougher M, Kunz A, Hamann PR, Evans D, Armellino D, Khandke K, Marquette K, Tchistiakova L, Boghaert ER, Abraham RT, Wistuba II, Zhou BB
Cancer research 2011 Jun 15;71(12):4236-46
Cancer research 2011 Jun 15;71(12):4236-46
Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
Lepore AC, O'Donnell J, Bonner JF, Paul C, Miller ME, Rauck B, Kushner RA, Rothstein JD, Fischer I, Maragakis NJ
Journal of neuroscience research 2011 Jul;89(7):1001-17
Journal of neuroscience research 2011 Jul;89(7):1001-17
Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.
Hsu HC, Yang P, Wu Q, Wang JH, Job G, Guentert T, Li J, Stockard CR, Le TV, Chaplin DD, Grizzle WE, Mountz JD
Arthritis and rheumatism 2011 Jul;63(7):2038-48
Arthritis and rheumatism 2011 Jul;63(7):2038-48
Gastrointestinal stromal tumours in children and young adults: a clinicopathologic series with long-term follow-up from the database of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Benesch M, Leuschner I, Wardelmann E, Thielen M, Schmid I, Kontny U, Ebetsberger G, Frey E, Graf N, Schneider DT, Kremens B, Amann G, Urban C, Schlemmer M, Quehenberger F, Klingebiel T, Dantonello T, Koscielniak E
European journal of cancer (Oxford, England : 1990) 2011 Jul;47(11):1692-8
European journal of cancer (Oxford, England : 1990) 2011 Jul;47(11):1692-8
Usefulness of p16ink4a, ProEX C, and Ki-67 for the diagnosis of glandular dysplasia and adenocarcinoma of the cervix uteri.
Negri G, Bellisano G, Carico E, Faa G, Kasal A, Antoniazzi S, Egarter-Vigl E, Piccin A, Dalla Palma P, Vittadello F
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2011 Jul;30(4):407-13
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2011 Jul;30(4):407-13
Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.
Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Borel Rinkes IH, Kranenburg O
Gastroenterology 2011 Jul;141(1):269-78
Gastroenterology 2011 Jul;141(1):269-78
Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer.
Barok M, Tanner M, Köninki K, Isola J
Cancer letters 2011 Jul 28;306(2):171-9
Cancer letters 2011 Jul 28;306(2):171-9
Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.
Meyer DS, Brinkhaus H, Müller U, Müller M, Cardiff RD, Bentires-Alj M
Cancer research 2011 Jul 1;71(13):4344-51
Cancer research 2011 Jul 1;71(13):4344-51
X-irradiation reduces the proliferation of astrocytes by cell cycle arrest.
Wang Q, Xu Y, Xie MJ, Yu ZY, Qin YY, Wang W, Zhu Z
Neuroscience letters 2011 Jul 1;498(1):78-83
Neuroscience letters 2011 Jul 1;498(1):78-83
CDKN1B/p27 expression in peripheral T cell lymphoma not otherwise specified.
Gazzola A, Sista MT, Agostinelli C, Righi S, Sapienza MR, Mannu C, Rossi M, Bacci F, Sabattini E, Went P, Zinzani PL, Pileri SA, Piccaluga PP
Journal of clinical pathology 2011 Jan;64(1):83-7
Journal of clinical pathology 2011 Jan;64(1):83-7
Analysis of the IgVH genes in T cell-mediated and antibody-mediated rejection of the kidney graft.
Bellan C, Amato T, Carmellini M, Onorati M, D'Amuri A, Leoncini L, del Vecchio MT
Journal of clinical pathology 2011 Jan;64(1):47-53
Journal of clinical pathology 2011 Jan;64(1):47-53
Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation.
Hur K, Niwa T, Toyoda T, Tsukamoto T, Tatematsu M, Yang HK, Ushijima T
Carcinogenesis 2011 Jan;32(1):35-41
Carcinogenesis 2011 Jan;32(1):35-41
Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice.
Mori M, Kitazume M, Ose R, Kurokawa J, Koga K, Osuga Y, Arai S, Miyazaki T
The Journal of clinical investigation 2011 Jan;121(1):318-27
The Journal of clinical investigation 2011 Jan;121(1):318-27
Quantitative assessment of hepatic function during liver regeneration in a standardized rat model.
de Graaf W, Bennink RJ, Heger M, Maas A, de Bruin K, van Gulik TM
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011 Feb;52(2):294-302
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011 Feb;52(2):294-302
Osteosarcoma arising in a long-standing uterine leiomyoma: a case report and literature review.
Wang RC, Wen MC, Wang J, Ho SC, Jan YJ
International journal of surgical pathology 2011 Feb;19(1):99-103
International journal of surgical pathology 2011 Feb;19(1):99-103
Ectopic endometrial tissue in mesonephric duct remnants in bitches.
Bartel C, Berghold P, Walter I
Reproduction in domestic animals = Zuchthygiene 2011 Dec;46(6):950-6
Reproduction in domestic animals = Zuchthygiene 2011 Dec;46(6):950-6
Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.
Abdelzaher E, El-Gendi SM, Yehya A, Gowil AG
British journal of neurosurgery 2011 Dec;25(6):707-13
British journal of neurosurgery 2011 Dec;25(6):707-13
Heat shock attenuates VEGF expression in three-dimensional myoblast sheets deteriorating therapeutic efficacy in heart failure.
Augustin M, Ali Asim Mahar M, Lakkisto P, Tikkanen I, Vento A, Patila T, Harjula A
Medical science monitor : international medical journal of experimental and clinical research 2011 Dec;17(12):BR345-53
Medical science monitor : international medical journal of experimental and clinical research 2011 Dec;17(12):BR345-53
The relationship among PDX1, CDX2, and mucin profiles in gastric carcinomas; correlations with clinicopathologic parameters.
Oz Puyan F, Can N, Ozyilmaz F, Usta U, Sut N, Tastekin E, Altaner S
Journal of cancer research and clinical oncology 2011 Dec;137(12):1749-62
Journal of cancer research and clinical oncology 2011 Dec;137(12):1749-62
Predicting IGF-1R therapy response in bone sarcomas: immuno-SPECT imaging with radiolabeled R1507.
Fleuren ED, Versleijen-Jonkers YM, van de Luijtgaarden AC, Molkenboer-Kuenen JD, Heskamp S, Roeffen MH, van Laarhoven HW, Houghton PJ, Oyen WJ, Boerman OC, van der Graaf WT
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Dec 15;17(24):7693-703
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Dec 15;17(24):7693-703
Optic nerve gliomas: role of Ki-67 staining of tumour and margins in predicting long-term outcome.
Yeung SN, White VA, Nimmo M, Rootman J
The British journal of ophthalmology 2011 Aug;95(8):1077-81
The British journal of ophthalmology 2011 Aug;95(8):1077-81
Enhancement of in vitro human tubulogenesis by endothelial cell-derived factors: implications for in vivo tubular regeneration after injury.
Miya M, Maeshima A, Mishima K, Sakurai N, Ikeuchi H, Kuroiwa T, Hiromura K, Yokoo H, Nojima Y
American journal of physiology. Renal physiology 2011 Aug;301(2):F387-95
American journal of physiology. Renal physiology 2011 Aug;301(2):F387-95
Increased diagnostic accuracy of atypical glandular cells in cervical liquid-based cytology using cell blocks.
Risse EK, Holierhoek JP, Meijer-Marres EM, Ouwerkerk-Noordam E, Boon ME
Cytopathology : official journal of the British Society for Clinical Cytology 2011 Aug;22(4):253-60
Cytopathology : official journal of the British Society for Clinical Cytology 2011 Aug;22(4):253-60
Lymphoepithelioma-like carcinoma of the ovary.
Ambrosio MR, Rocca BJ, Onorati M, Mourmouras V, Mastrogiulio MG, Crispino S, Liberatore C, Santopietro R
International journal of surgical pathology 2011 Aug;19(4):514-7
International journal of surgical pathology 2011 Aug;19(4):514-7
Validation of MdmX as a therapeutic target for reactivating p53 in tumors.
Garcia D, Warr MR, Martins CP, Brown Swigart L, Passegué E, Evan GI
Genes & development 2011 Aug 15;25(16):1746-57
Genes & development 2011 Aug 15;25(16):1746-57
Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.
Nogueira L, Ruiz-Ontañon P, Vazquez-Barquero A, Lafarga M, Berciano MT, Aldaz B, Grande L, Casafont I, Segura V, Robles EF, Suarez D, Garcia LF, Martinez-Climent JA, Fernandez-Luna JL
Oncogene 2011 Aug 11;30(32):3537-48
Oncogene 2011 Aug 11;30(32):3537-48
Tumour eosinophilia combined with an immunohistochemistry panel is useful in the differentiation of type B3 thymoma from thymic carcinoma.
Khoury T, Chandrasekhar R, Wilding G, Tan D, Cheney RT
International journal of experimental pathology 2011 Apr;92(2):87-96
International journal of experimental pathology 2011 Apr;92(2):87-96
Cyclooxygenase-2 supports tumor proliferation in vestibular schwannomas.
Hong B, Krusche CA, Schwabe K, Friedrich S, Klein R, Krauss JK, Nakamura M
Neurosurgery 2011 Apr;68(4):1112-7
Neurosurgery 2011 Apr;68(4):1112-7
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.
Navis AC, Hamans BC, Claes A, Heerschap A, Jeuken JW, Wesseling P, Leenders WP
The Journal of pathology 2011 Apr;223(5):626-34
The Journal of pathology 2011 Apr;223(5):626-34
Infrared radiation does not enhance the frequency of ultraviolet radiation-induced skin tumors, but their growth behaviour in mice.
Jantschitsch C, Weichenthal M, Maeda A, Proksch E, Schwarz T, Schwarz A
Experimental dermatology 2011 Apr;20(4):346-50
Experimental dermatology 2011 Apr;20(4):346-50
Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?
Eloy C, Vinagre J, Cameselle-Teijeiro J, Paiva ME, Soares P, Sobrinho-Simões M
International journal of surgical pathology 2011 Apr;19(2):276-80
International journal of surgical pathology 2011 Apr;19(2):276-80
Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target.
Pode-Shakked N, Harari-Steinberg O, Haberman-Ziv Y, Rom-Gross E, Bahar S, Omer D, Metsuyanim S, Buzhor E, Jacob-Hirsch J, Goldstein RS, Mark-Danieli M, Dekel B
Oncogene 2011 Apr 7;30(14):1664-80
Oncogene 2011 Apr 7;30(14):1664-80
Autophagy-deficient mice develop multiple liver tumors.
Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S, Eishi Y, Hino O, Tanaka K, Mizushima N
Genes & development 2011 Apr 15;25(8):795-800
Genes & development 2011 Apr 15;25(8):795-800
Species differences in reactivity of mouse and rat astrocytes in vitro.
Puschmann TB, Dixon KJ, Turnley AM
Neuro-Signals 2010;18(3):152-63
Neuro-Signals 2010;18(3):152-63
A comparison of Ki-67 antigen presentation in acute generalized exanthematous pustulosis and pustular psoriasis.
Chang SL, Hu S, Hung SI, Huang YL, Hsiao WC, Chung WH
Archives of dermatological research 2010 Sep;302(7):525-9
Archives of dermatological research 2010 Sep;302(7):525-9
Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation.
Merfeld-Clauss S, Gollahalli N, March KL, Traktuev DO
Tissue engineering. Part A 2010 Sep;16(9):2953-66
Tissue engineering. Part A 2010 Sep;16(9):2953-66
Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth.
Mellick AS, Plummer PN, Nolan DJ, Gao D, Bambino K, Hahn M, Catena R, Turner V, McDonnell K, Benezra R, Brink R, Swarbrick A, Mittal V
Cancer research 2010 Sep 15;70(18):7273-82
Cancer research 2010 Sep 15;70(18):7273-82
The role of keratinocyte growth factor in melanogenesis: a possible mechanism for the initiation of solar lentigines.
Chen N, Hu Y, Li WH, Eisinger M, Seiberg M, Lin CB
Experimental dermatology 2010 Oct;19(10):865-72
Experimental dermatology 2010 Oct;19(10):865-72
Antiangiogenic effect of licochalcone A.
Kim YH, Shin EK, Kim DH, Lee HH, Park JH, Kim JK
Biochemical pharmacology 2010 Oct 15;80(8):1152-9
Biochemical pharmacology 2010 Oct 15;80(8):1152-9
111In-bevacizumab imaging of renal cell cancer and evaluation of neoadjuvant treatment with the vascular endothelial growth factor receptor inhibitor sorafenib.
Desar IM, Stillebroer AB, Oosterwijk E, Leenders WP, van Herpen CM, van der Graaf WT, Boerman OC, Mulders PF, Oyen WJ
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010 Nov;51(11):1707-15
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010 Nov;51(11):1707-15
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark.
Revenko AS, Kalashnikova EV, Gemo AT, Zou JX, Chen HW
Molecular and cellular biology 2010 Nov;30(22):5260-72
Molecular and cellular biology 2010 Nov;30(22):5260-72
Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231.
Morini M, Astigiano S, Gitton Y, Emionite L, Mirisola V, Levi G, Barbieri O
BMC cancer 2010 Nov 25;10:649
BMC cancer 2010 Nov 25;10:649
Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.
DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE
BMC developmental biology 2010 Nov 10;10:112
BMC developmental biology 2010 Nov 10;10:112
Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.
Gordon SN, Cervasi B, Odorizzi P, Silverman R, Aberra F, Ginsberg G, Estes JD, Paiardini M, Frank I, Silvestri G
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 1;185(9):5169-79
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 1;185(9):5169-79
PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity.
Zhang CC, Yan Z, Zhang Q, Kuszpit K, Zasadny K, Qiu M, Painter CL, Wong A, Kraynov E, Arango ME, Mehta PP, Popoff I, Casperson GF, Los G, Bender S, Anderes K, Christensen JG, VanArsdale T
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Nov 1;16(21):5177-88
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Nov 1;16(21):5177-88
A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.
Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S
Molecular cancer therapeutics 2010 May;9(5):1136-46
Molecular cancer therapeutics 2010 May;9(5):1136-46
TGF-beta1 causes epithelial-mesenchymal transition in HaCaT derivatives, but induces expression of COX-2 and migration only in benign, not in malignant keratinocytes.
Räsänen K, Vaheri A
Journal of dermatological science 2010 May;58(2):97-104
Journal of dermatological science 2010 May;58(2):97-104
Expression of Ki-67, PCNA, and p27kip1 in canine pituitary corticotroph adenomas.
van Rijn SJ, Grinwis GC, Penning LC, Meij BP
Domestic animal endocrinology 2010 May;38(4):244-52
Domestic animal endocrinology 2010 May;38(4):244-52
Eph receptor tyrosine kinases regulate astrocyte cytoskeletal rearrangement and focal adhesion formation.
Puschmann TB, Turnley AM
Journal of neurochemistry 2010 May;113(4):881-94
Journal of neurochemistry 2010 May;113(4):881-94
The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development.
Maruyama T, Mirando AJ, Deng CX, Hsu W
Science signaling 2010 May 25;3(123):ra40
Science signaling 2010 May 25;3(123):ra40
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.
Murray BW, Guo C, Piraino J, Westwick JK, Zhang C, Lamerdin J, Dagostino E, Knighton D, Loi CM, Zager M, Kraynov E, Popoff I, Christensen JG, Martinez R, Kephart SE, Marakovits J, Karlicek S, Bergqvist S, Smeal T
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9446-51
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9446-51
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
Pechloff K, Holch J, Ferch U, Schweneker M, Brunner K, Kremer M, Sparwasser T, Quintanilla-Martinez L, Zimber-Strobl U, Streubel B, Gewies A, Peschel C, Ruland J
The Journal of experimental medicine 2010 May 10;207(5):1031-44
The Journal of experimental medicine 2010 May 10;207(5):1031-44
Desmoplastic small round cell tumor of the submandibular gland--a rare but distinctive primary salivary gland neoplasm.
Yin WH, Guo SP, Yang HY, Chan JK
Human pathology 2010 Mar;41(3):438-42
Human pathology 2010 Mar;41(3):438-42
Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management.
Ghosh R, Graham H, Rivas P, Tan XJ, Crosby K, Bhaskaran S, Schoolfield J, Banu J, Fernandes G, Yeh IT, Kumar AP
Anticancer research 2010 Mar;30(3):857-65
Anticancer research 2010 Mar;30(3):857-65
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment.
de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L
The American journal of pathology 2010 Mar;176(3):1229-40
The American journal of pathology 2010 Mar;176(3):1229-40
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Chen S, Sanford CA, Sun J, Choi V, Van Dyke T, Samulski RJ, Rathmell WK
Angiogenesis 2010 Mar;13(1):59-69
Angiogenesis 2010 Mar;13(1):59-69
Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
Efferson CL, Winkelmann CT, Ware C, Sullivan T, Giampaoli S, Tammam J, Patel S, Mesiti G, Reilly JF, Gibson RE, Buser C, Yeatman T, Coppola D, Winter C, Clark EA, Draetta GF, Strack PR, Majumder PK
Cancer research 2010 Mar 15;70(6):2476-84
Cancer research 2010 Mar 15;70(6):2476-84
PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.
Bartholomeusz C, Gonzalez-Angulo AM, Kazansky A, Krishnamurthy S, Liu P, Yuan LX, Yamasaki F, Liu S, Hayashi N, Zhang D, Esteva FJ, Hortobagyi GN, Ueno NT
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Mar 15;16(6):1802-11
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Mar 15;16(6):1802-11
Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos.
Komada M, Fujiyama F, Yamada S, Shiota K, Nagao T
Birth defects research. Part B, Developmental and reproductive toxicology 2010 Jun;89(3):213-22
Birth defects research. Part B, Developmental and reproductive toxicology 2010 Jun;89(3):213-22
Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase.
Stroo I, Stokman G, Teske GJ, Raven A, Butter LM, Florquin S, Leemans JC
International immunology 2010 Jun;22(6):433-42
International immunology 2010 Jun;22(6):433-42
What would be left behind if subtotal thyroidectomy were preferred instead of total thyroidectomy?
Tekin K, Yilmaz S, Yalçin N, Coban S, Aydin C, Kabay B, Erdem E, Ozbaş S, Ozden A
American journal of surgery 2010 Jun;199(6):765-9
American journal of surgery 2010 Jun;199(6):765-9
Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome.
Bianchi P, Ciani E, Guidi S, Trazzi S, Felice D, Grossi G, Fernandez M, Giuliani A, Calzà L, Bartesaghi R
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jun 30;30(26):8769-79
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jun 30;30(26):8769-79
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis.
Hendrix A, Maynard D, Pauwels P, Braems G, Denys H, Van den Broecke R, Lambert J, Van Belle S, Cocquyt V, Gespach C, Bracke M, Seabra MC, Gahl WA, De Wever O, Westbroek W
Journal of the National Cancer Institute 2010 Jun 16;102(12):866-80
Journal of the National Cancer Institute 2010 Jun 16;102(12):866-80
Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.
Cohen I, Maoz M, Turm H, Grisaru-Granovsky S, Maly B, Uziely B, Weiss E, Abramovitch R, Gross E, Barzilay O, Qiu Y, Bar-Shavit R
PloS one 2010 Jun 15;5(6):e11135
PloS one 2010 Jun 15;5(6):e11135
Thyroid transcription factor-1 influences the early phase of compensatory lung growth in adult mice.
Takahashi Y, Izumi Y, Kohno M, Kimura T, Kawamura M, Okada Y, Nomori H, Ikeda E
American journal of respiratory and critical care medicine 2010 Jun 15;181(12):1397-406
American journal of respiratory and critical care medicine 2010 Jun 15;181(12):1397-406
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Räsänen K, Vaheri A
Experimental cell research 2010 Jun 10;316(10):1739-47
Experimental cell research 2010 Jun 10;316(10):1739-47
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure.
Nguyen Dinh Cat A, Griol-Charhbili V, Loufrani L, Labat C, Benjamin L, Farman N, Lacolley P, Henrion D, Jaisser F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Jul;24(7):2454-63
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Jul;24(7):2454-63
Evaluation of clinico-pathological criteria and the Ki67 index as prognostic indicators in canine insulinoma.
Buishand FO, Kik M, Kirpensteijn J
Veterinary journal (London, England : 1997) 2010 Jul;185(1):62-7
Veterinary journal (London, England : 1997) 2010 Jul;185(1):62-7
Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report.
Pacheco M, Horsman DE, Hayes MM, Clarkson PW, Huwait H, Nielsen TO
Molecular cytogenetics 2010 Jul 2;3:12
Molecular cytogenetics 2010 Jul 2;3:12
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.
Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB
International journal of cancer 2010 Jul 15;127(2):257-68
International journal of cancer 2010 Jul 15;127(2):257-68
A class discovery and class prediction approach to histopathological classification of mammographic screen detected columnar cell lesions of the breast.
Pathmanathan N, Salisbury EL, Provan PJ, Bilous AM, Byth K, Milliken JS, Clarke CL, Balleine RL
Pathology 2010 Jan;42(1):28-36
Pathology 2010 Jan;42(1):28-36
Synchronous presentation of GISTs and other primary neoplasms: a single center experience.
Arnogiannaki N, Martzoukou I, Kountourakis P, Dimitriadis E, Papathanasaki A, Nastoulis E, Gazalidou M, Fida A, Apostolikas N, Agnantis NJ
In vivo (Athens, Greece) 2010 Jan-Feb;24(1):109-15
In vivo (Athens, Greece) 2010 Jan-Feb;24(1):109-15
Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
Tharakan ST, Inamoto T, Sung B, Aggarwal BB, Kamat AM
Biochemical pharmacology 2010 Jan 15;79(2):218-28
Biochemical pharmacology 2010 Jan 15;79(2):218-28
Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.
Laine H, Sulg M, Kirjavainen A, Pirvola U
Developmental biology 2010 Jan 1;337(1):134-46
Developmental biology 2010 Jan 1;337(1):134-46
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
Osada M, Jardine L, Misir R, Andl T, Millar SE, Pezzano M
PloS one 2010 Feb 8;5(2):e9062
PloS one 2010 Feb 8;5(2):e9062
High-precision radiosurgical dose delivery by interlaced microbeam arrays of high-flux low-energy synchrotron X-rays.
Serduc R, Bräuer-Krisch E, Siegbahn EA, Bouchet A, Pouyatos B, Carron R, Pannetier N, Renaud L, Berruyer G, Nemoz C, Brochard T, Rémy C, Barbier EL, Bravin A, Le Duc G, Depaulis A, Estève F, Laissue JA
PloS one 2010 Feb 3;5(2):e9028
PloS one 2010 Feb 3;5(2):e9028
Diagnostic value of p16INK4A, Ki-67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens.
Yu L, Wang L, Zhong J, Chen S
Cancer cytopathology 2010 Feb 25;118(1):47-55
Cancer cytopathology 2010 Feb 25;118(1):47-55
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.
Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, Shen R, Zhang MY, Strassle BW, Lu P, Mark L, Piesla MJ, Deng K, Kouranova EV, Ring RH, Whiteside GT, Bates B, Walsh FS, Williams G, Pangalos MN, Samad TA, Doherty P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Feb 10;30(6):2017-24
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Feb 10;30(6):2017-24
Extraribosomal function of metallopanstimulin-1: reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growth.
Dai Y, Pierson SE, Dudney WC, Stack BC Jr
International journal of cancer 2010 Feb 1;126(3):611-9
International journal of cancer 2010 Feb 1;126(3):611-9
Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo.
Schwaiberger AV, Heiss EH, Cabaravdic M, Oberan T, Zaujec J, Schachner D, Uhrin P, Atanasov AG, Breuss JM, Binder BR, Dirsch VM
Arteriosclerosis, thrombosis, and vascular biology 2010 Dec;30(12):2475-81
Arteriosclerosis, thrombosis, and vascular biology 2010 Dec;30(12):2475-81
Evaluation of the presence of Helicobacter species in the biliary system of Turkish patients with cholelithiasis.
Bostanoğlu E, Karahan ZC, Bostanoğlu A, Savaş B, Erden E, Kiyan M
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2010 Dec;21(4):421-7
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2010 Dec;21(4):421-7
Immuno-histochemical evaluation of solar lentigines: The association of KGF/KGFR and other factors with lesion development.
Lin CB, Hu Y, Rossetti D, Chen N, David C, Slominski A, Seiberg M
Journal of dermatological science 2010 Aug;59(2):91-7
Journal of dermatological science 2010 Aug;59(2):91-7
Acute ANIT toxicity in male IL-10 knockout and wild-type mice.
Faiola B, Peterson RA, Kimbrough CL, Jordan HL, Cullen JM
Toxicologic pathology 2010 Aug;38(5):745-55
Toxicologic pathology 2010 Aug;38(5):745-55
S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer.
Wang XH, Zhang LH, Zhong XY, Xing XF, Liu YQ, Niu ZJ, Peng Y, Du H, Zhang GG, Hu Y, Liu N, Zhu YB, Ge SH, Zhao W, Lu AP, Li JY, Ji JF
The American journal of pathology 2010 Aug;177(2):586-97
The American journal of pathology 2010 Aug;177(2):586-97
Heparanase expression of glioma in human and animal models.
Hong X, Nelson KK, deCarvalho AC, Kalkanis SN
Journal of neurosurgery 2010 Aug;113(2):261-9
Journal of neurosurgery 2010 Aug;113(2):261-9
Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells.
Ables JL, Decarolis NA, Johnson MA, Rivera PD, Gao Z, Cooper DC, Radtke F, Hsieh J, Eisch AJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 4;30(31):10484-92
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 4;30(31):10484-92
The pathogenic role of Epstein-Barr virus (EBV) in sclerosing polycystic adenosis.
Swelam WM
Pathology, research and practice 2010 Aug 15;206(8):565-71
Pathology, research and practice 2010 Aug 15;206(8):565-71
Therapeutic antibody targeting of individual Notch receptors.
Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW
Nature 2010 Apr 15;464(7291):1052-7
Nature 2010 Apr 15;464(7291):1052-7
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
de Bruijn MT, Raats DA, Hoogwater FJ, van Houdt WJ, Cameron K, Medema JP, Borel Rinkes IH, Kranenburg O
British journal of cancer 2010 Apr 13;102(8):1254-64
British journal of cancer 2010 Apr 13;102(8):1254-64
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.
Andrieu C, Taieb D, Baylot V, Ettinger S, Soubeyran P, De-Thonel A, Nelson C, Garrido C, So A, Fazli L, Bladou F, Gleave M, Iovanna JL, Rocchi P
Oncogene 2010 Apr 1;29(13):1883-96
Oncogene 2010 Apr 1;29(13):1883-96
Soy consumption and histopathologic markers in breast tissue using tissue microarrays.
Maskarinec G, Erber E, Verheus M, Hernandez BY, Killeen J, Cashin S, Cline JM
Nutrition and cancer 2009;61(5):708-16
Nutrition and cancer 2009;61(5):708-16
Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.
Horváth E, Mezei T, Pávai Z, Turcu M, Demian S, Tóth E, Chira L, Jung I
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2009;50(3):399-406
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2009;50(3):399-406
Ki-67 in screen-detected, low-grade, low-stage prostate cancer, relation to prostate-specific antigen doubling time, Gleason score and prostate-specific antigen relapse after radical prostatectomy.
Khatami A, Hugosson J, Wang W, Damber JE
Scandinavian journal of urology and nephrology 2009;43(1):12-8
Scandinavian journal of urology and nephrology 2009;43(1):12-8
Dicer is required for maintaining adult pancreas.
Morita S, Hara A, Kojima I, Horii T, Kimura M, Kitamura T, Ochiya T, Nakanishi K, Matoba R, Matsubara K, Hatada I
PloS one 2009;4(1):e4212
PloS one 2009;4(1):e4212
Effect of yeast-derived beta-glucan in conjunction with bevacizumab for the treatment of human lung adenocarcinoma in subcutaneous and orthotopic xenograft models.
Zhong W, Hansen R, Li B, Cai Y, Salvador C, Moore GD, Yan J
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Sep;32(7):703-12
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Sep;32(7):703-12
Cross-species immunohistochemical investigation of the activation of the liver progenitor cell niche in different types of liver disease.
Schotanus BA, van den Ingh TS, Penning LC, Rothuizen J, Roskams TA, Spee B
Liver international : official journal of the International Association for the Study of the Liver 2009 Sep;29(8):1241-52
Liver international : official journal of the International Association for the Study of the Liver 2009 Sep;29(8):1241-52
Immunohistochemical expression of SPARC is correlated with recurrence, survival and malignant potential in meningiomas.
Bozkurt SU, Ayan E, Bolukbasi F, Elmaci I, Pamir N, Sav A
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Sep;117(9):651-9
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Sep;117(9):651-9
A 19-year follow-up of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome who developed non-Hodgkin lymphoma.
Balci S, Engiz O, Okten G, Sipahier M, Gursu G, Kandemir B
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2009 Sep;108(3):e91-5
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2009 Sep;108(3):e91-5
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Zhang W, Zhu J, Efferson CL, Ware C, Tammam J, Angagaw M, Laskey J, Bettano KA, Kasibhatla S, Reilly JF, Sur C, Majumder PK
Cancer research 2009 Sep 15;69(18):7466-72
Cancer research 2009 Sep 15;69(18):7466-72
Gender differences in pulmonary regenerative response to naphthalene-induced bronchiolar epithelial cell injury.
Oliver JR, Kushwah R, Wu J, Cutz E, Yeger H, Waddell TK, Hu J
Cell proliferation 2009 Oct;42(5):672-87
Cell proliferation 2009 Oct;42(5):672-87
Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence.
Richardson HN, Chan SH, Crawford EF, Lee YK, Funk CK, Koob GF, Mandyam CD
Neurobiology of disease 2009 Oct;36(1):1-10
Neurobiology of disease 2009 Oct;36(1):1-10
Leukemia inhibitory factor favours neurogenic differentiation of long-term propagated human midbrain precursor cells.
Andersen RK, Widmer HR, Zimmer J, Wahlberg LU, Meyer M
Neuroscience letters 2009 Oct 30;464(3):203-8
Neuroscience letters 2009 Oct 30;464(3):203-8
Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.
Yawno T, Hirst JJ, Castillo-Melendez M, Walker DW
Neuroscience 2009 Oct 20;163(3):838-47
Neuroscience 2009 Oct 20;163(3):838-47
Predicting recurrence of nonfunctioning pituitary adenomas.
Noh TW, Jeong HJ, Lee MK, Kim TS, Kim SH, Lee EJ
The Journal of clinical endocrinology and metabolism 2009 Nov;94(11):4406-13
The Journal of clinical endocrinology and metabolism 2009 Nov;94(11):4406-13
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer.
Debucquoy A, Roels S, Goethals L, Libbrecht L, Van Cutsem E, Geboes K, Penninckx F, D'Hoore A, McBride WH, Haustermans K
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009 Nov;93(2):273-8
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009 Nov;93(2):273-8
Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles.
Lopes N, Sousa B, Vieira D, Milanezi F, Schmitt F
Histopathology 2009 Nov;55(5):594-9
Histopathology 2009 Nov;55(5):594-9
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions.
Utheim TP, Raeder S, Olstad OK, Utheim ØA, de La Paz M, Cheng R, Huynh TT, Messelt E, Roald B, Lyberg T
Investigative ophthalmology & visual science 2009 Nov;50(11):5165-72
Investigative ophthalmology & visual science 2009 Nov;50(11):5165-72
Tumour control by whole brain irradiation of anti-VEGF-treated mice bearing intracerebral glioma.
Verhoeff JJ, Stalpers LJ, Claes A, Hovinga KE, Musters GD, Peter Vandertop W, Richel DJ, Leenders WP, van Furth WR
European journal of cancer (Oxford, England : 1990) 2009 Nov;45(17):3074-80
European journal of cancer (Oxford, England : 1990) 2009 Nov;45(17):3074-80
Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK
British journal of pharmacology 2009 Nov;158(5):1183-95
British journal of pharmacology 2009 Nov;158(5):1183-95
In pursuit of leucine-rich repeat-containing G protein-coupled receptor-5 regulation and function in the uterus.
Sun X, Jackson L, Dey SK, Daikoku T
Endocrinology 2009 Nov;150(11):5065-73
Endocrinology 2009 Nov;150(11):5065-73
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
Li Z, Carrier L, Belame A, Thiyagarajah A, Salvo VA, Burow ME, Rowan BG
Breast cancer research and treatment 2009 Nov;118(1):33-43
Breast cancer research and treatment 2009 Nov;118(1):33-43
Synchrotron microbeam radiation therapy for rat brain tumor palliation-influence of the microbeam width at constant valley dose.
Serduc R, Bouchet A, Bräuer-Krisch E, Laissue JA, Spiga J, Sarun S, Bravin A, Fonta C, Renaud L, Boutonnat J, Siegbahn EA, Estève F, Le Duc G
Physics in medicine and biology 2009 Nov 7;54(21):6711-24
Physics in medicine and biology 2009 Nov 7;54(21):6711-24
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
Ghosh R, Schoolfield J, Yeh IT, Smith ML, Hursting SD, Chan DC, Lucia MS, Kumar AP
Translational oncology 2009 May;2(2):65-72
Translational oncology 2009 May;2(2):65-72
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
Ghosh R, Schoolfield J, Yeh IT, Smith ML, Hursting SD, Chan DC, Lucia MS, Kumar AP
Translational oncology 2009 May;2(2):65-72
Translational oncology 2009 May;2(2):65-72
A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).
Limsirichaikul S, Niimi A, Fawcett H, Lehmann A, Yamashita S, Ogi T
Nucleic acids research 2009 Mar;37(4):e31
Nucleic acids research 2009 Mar;37(4):e31
Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa: age-related progression.
Kondo K, Watanabe K, Sakamoto T, Suzukawa K, Nibu K, Kaga K, Yamasoba T
Cell and tissue research 2009 Mar;335(3):489-503
Cell and tissue research 2009 Mar;335(3):489-503
Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation.
Wang W, Bergh A, Damber JE
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Mar;117(3):185-95
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Mar;117(3):185-95
Energetics and mammary carcinogenesis: effects of moderate-intensity running and energy intake on cellular processes and molecular mechanisms in rats.
Zhu Z, Jiang W, McGinley JN, Thompson HJ
Journal of applied physiology (Bethesda, Md. : 1985) 2009 Mar;106(3):911-8
Journal of applied physiology (Bethesda, Md. : 1985) 2009 Mar;106(3):911-8
Prognostic significance of oncogenic markers in ductal carcinoma in situ of the breast: a clinicopathologic study.
Altintas S, Lambein K, Huizing MT, Braems G, Asjoe FT, Hellemans H, Van Marck E, Weyler J, Praet M, Van den Broecke R, Vermorken JB, Tjalma WA
The breast journal 2009 Mar-Apr;15(2):120-32
The breast journal 2009 Mar-Apr;15(2):120-32
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH, Galon J
Cancer research 2009 Mar 15;69(6):2685-93
Cancer research 2009 Mar 15;69(6):2685-93
Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.
Schauer IG, Ressler SJ, Rowley DR
The Prostate 2009 Mar 1;69(4):373-84
The Prostate 2009 Mar 1;69(4):373-84
Amplification of the urokinase-type plasminogen activator receptor (uPAR) gene in ductal pancreatic carcinomas identifies a clinically high-risk group.
Hildenbrand R, Niedergethmann M, Marx A, Belharazem D, Allgayer H, Schleger C, Ströbel P
The American journal of pathology 2009 Jun;174(6):2246-53
The American journal of pathology 2009 Jun;174(6):2246-53
Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.
Vuorenoja S, Mohanty BP, Arola J, Huhtaniemi I, Toppari J, Rahman NA
Endocrine-related cancer 2009 Jun;16(2):549-64
Endocrine-related cancer 2009 Jun;16(2):549-64
Mammographic density and epithelial histopathologic markers.
Verheus M, Maskarinec G, Erber E, Steude JS, Killeen J, Hernandez BY, Cline JM
BMC cancer 2009 Jun 13;9:182
BMC cancer 2009 Jun 13;9:182
Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.
Goel VK, Ibrahim N, Jiang G, Singhal M, Fee S, Flotte T, Westmoreland S, Haluska FS, Hinds PW, Haluska FG
Oncogene 2009 Jun 11;28(23):2289-98
Oncogene 2009 Jun 11;28(23):2289-98
Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer.
Gravdal K, Halvorsen OJ, Haukaas SA, Akslen LA
Cancer research 2009 Jun 1;69(11):4708-15
Cancer research 2009 Jun 1;69(11):4708-15
Apoptosis-related (survivin, Bcl-2), tumor suppressor gene (p53), proliferation (Ki-67), and non-receptor tyrosine kinase (Src) markers expression and correlation with clinicopathologic variables in 60 thymic neoplasms.
Khoury T, Arshad A, Bogner P, Ramnath N, Zhang S, Chandrasekhar R, Wilding G, Alrawi S, Tan D
Chest 2009 Jul;136(1):220-228
Chest 2009 Jul;136(1):220-228
Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.
Dupressoir A, Vernochet C, Bawa O, Harper F, Pierron G, Opolon P, Heidmann T
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 21;106(29):12127-32
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 21;106(29):12127-32
A limited panel of immunomarkers can reliably distinguish between clear cell and high-grade serous carcinoma of the ovary.
Köbel M, Kalloger SE, Carrick J, Huntsman D, Asad H, Oliva E, Ewanowich CA, Soslow RA, Gilks CB
The American journal of surgical pathology 2009 Jan;33(1):14-21
The American journal of surgical pathology 2009 Jan;33(1):14-21
Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo.
Galvez AS, Duran A, Linares JF, Pathrose P, Castilla EA, Abu-Baker S, Leitges M, Diaz-Meco MT, Moscat J
Molecular and cellular biology 2009 Jan;29(1):104-15
Molecular and cellular biology 2009 Jan;29(1):104-15
Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice.
Shima H, Takubo K, Iwasaki H, Yoshihara H, Gomei Y, Hosokawa K, Arai F, Takahashi T, Suda T
Biochemical and biophysical research communications 2009 Jan 16;378(3):467-72
Biochemical and biophysical research communications 2009 Jan 16;378(3):467-72
EphA2 as a promoter of melanoma tumorigenicity.
Margaryan NV, Strizzi L, Abbott DE, Seftor EA, Rao MS, Hendrix MJ, Hess AR
Cancer biology & therapy 2009 Feb;8(3):279-88
Cancer biology & therapy 2009 Feb;8(3):279-88
EphA2 as a promoter of melanoma tumorigenicity.
Margaryan NV, Strizzi L, Abbott DE, Seftor EA, Rao MS, Hendrix MJ, Hess AR
Cancer biology & therapy 2009 Feb;8(3):279-88
Cancer biology & therapy 2009 Feb;8(3):279-88
Cypermethrin effects on the adult mice seminal glands.
Rodriguez H, Tamayo C, Inostroza J, Soto C, Bustos-Obregón E, Paniagua R
Ecotoxicology and environmental safety 2009 Feb;72(2):658-62
Ecotoxicology and environmental safety 2009 Feb;72(2):658-62
Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.
Vick B, Weber A, Urbanik T, Maass T, Teufel A, Krammer PH, Opferman JT, Schuchmann M, Galle PR, Schulze-Bergkamen H
Hepatology (Baltimore, Md.) 2009 Feb;49(2):627-36
Hepatology (Baltimore, Md.) 2009 Feb;49(2):627-36
FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions.
Taflin C, Miyara M, Nochy D, Valeyre D, Naccache JM, Altare F, Salek-Peyron P, Badoual C, Bruneval P, Haroche J, Mathian A, Amoura Z, Hill G, Gorochov G
The American journal of pathology 2009 Feb;174(2):497-508
The American journal of pathology 2009 Feb;174(2):497-508
Role of the microenvironment for radiosensitization by patupilone.
Bley CR, Jochum W, Orlowski K, Furmanova P, Vuong V, McSheehy PM, Pruschy M
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Feb 15;15(4):1335-42
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Feb 15;15(4):1335-42
Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide.
Wang P, Xu TY, Guan YF, Su DF, Fan GR, Miao CY
Cardiovascular research 2009 Feb 1;81(2):370-80
Cardiovascular research 2009 Feb 1;81(2):370-80
Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice.
Freitag TL, Rietdijk S, Junker Y, Popov Y, Bhan AK, Kelly CP, Terhorst C, Schuppan D
Gut 2009 Dec;58(12):1597-605
Gut 2009 Dec;58(12):1597-605
Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation.
Grande MT, Arévalo M, Núñez A, Cannata-Andía JB, Santos E, López-Novoa JM
World journal of urology 2009 Dec;27(6):787-97
World journal of urology 2009 Dec;27(6):787-97
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
Behzatoğlu K, Durak H, Canberk S, Aydin O, Huq GE, Oznur M, Ozyalvaçli G, Yildiz P
Diagnostic pathology 2009 Dec 31;4:48
Diagnostic pathology 2009 Dec 31;4:48
Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice.
Farioli-Vecchioli S, Saraulli D, Costanzi M, Leonardi L, Cinà I, Micheli L, Nutini M, Longone P, Oh SP, Cestari V, Tirone F
PloS one 2009 Dec 17;4(12):e8339
PloS one 2009 Dec 17;4(12):e8339
Prolactin treatment improves engraftment and function of transplanted pancreatic islets.
Johansson M, Olerud J, Jansson L, Carlsson PO
Endocrinology 2009 Apr;150(4):1646-53
Endocrinology 2009 Apr;150(4):1646-53
Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.
Pfister S, Remke M, Castoldi M, Bai AH, Muckenthaler MU, Kulozik A, von Deimling A, Pscherer A, Lichter P, Korshunov A
Acta neuropathologica 2009 Apr;117(4):457-64
Acta neuropathologica 2009 Apr;117(4):457-64
Craniofacial malformation in R-spondin2 knockout mice.
Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K
Biochemical and biophysical research communications 2009 Apr 10;381(3):453-8
Biochemical and biophysical research communications 2009 Apr 10;381(3):453-8
Plasmoblastic lymphoma associated with human immunodeficiency virus.
Horváth E, Krenács L, Bagdi E, Pávai Z, Macarie I, Nagy EE, Demian S
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2008;49(3):309-14
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2008;49(3):309-14
Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study.
Crabb SJ, Bajdik CD, Leung S, Speers CH, Kennecke H, Huntsman DG, Gelmon KA
Breast cancer research : BCR 2008;10(1):R6
Breast cancer research : BCR 2008;10(1):R6
Serdin1/Lrrc10 is dispensable for mouse development.
Manuylov NL, Manuylova E, Avdoshina V, Tevosian S
Genesis (New York, N.Y. : 2000) 2008 Sep;46(9):441-6
Genesis (New York, N.Y. : 2000) 2008 Sep;46(9):441-6
Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.
Nozik-Grayck E, Suliman HB, Majka S, Albietz J, Van Rheen Z, Roush K, Stenmark KR
American journal of physiology. Lung cellular and molecular physiology 2008 Sep;295(3):L422-30
American journal of physiology. Lung cellular and molecular physiology 2008 Sep;295(3):L422-30
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP
The Journal of clinical investigation 2008 Sep;118(9):3065-74
The Journal of clinical investigation 2008 Sep;118(9):3065-74
Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions.
Shen Q, Wang Y, Kokovay E, Lin G, Chuang SM, Goderie SK, Roysam B, Temple S
Cell stem cell 2008 Sep 11;3(3):289-300
Cell stem cell 2008 Sep 11;3(3):289-300
Activated Akt as an indicator of prognosis in gastric cancer.
Cinti C, Vindigni C, Zamparelli A, La Sala D, Epistolato MC, Marrelli D, Cevenini G, Tosi P
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Coordinated expression of activated mitogen-activated protein kinases in salivary gland adenoid cystic carcinoma.
Handra-Luca A, Mauguen A, Ménard P, Fouret P
Human pathology 2008 Nov;39(11):1590-6
Human pathology 2008 Nov;39(11):1590-6
Mechanisms associated with dose-dependent inhibition of rat mammary carcinogenesis by dry bean (Phaseolus vulgaris, L.).
Thompson MD, Thompson HJ, Brick MA, McGinley JN, Jiang W, Zhu Z, Wolfe P
The Journal of nutrition 2008 Nov;138(11):2091-7
The Journal of nutrition 2008 Nov;138(11):2091-7
Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment.
Graf N, Herrmann K, den Hollander J, Fend F, Schuster T, Wester HJ, Senekowitsch-Schmidtke R, zum Büschenfelde CM, Peschel C, Schwaiger M, Dechow T, Buck AK
Molecular imaging and biology 2008 Nov-Dec;10(6):349-55
Molecular imaging and biology 2008 Nov-Dec;10(6):349-55
Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver.
Furrer K, Tian Y, Pfammatter T, Jochum W, El-Badry AM, Graf R, Clavien PA
Hepatology (Baltimore, Md.) 2008 May;47(5):1615-23
Hepatology (Baltimore, Md.) 2008 May;47(5):1615-23
Effect of leukemia inhibitory factor on long-term propagation of precursor cells derived from rat forebrain subventricular zone and ventral mesencephalon.
Andersen RK, Zimmer J, Wahlberg LU, Meyer M
Experimental neurology 2008 May;211(1):301-10
Experimental neurology 2008 May;211(1):301-10
The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.
Palazuelos J, Davoust N, Julien B, Hatterer E, Aguado T, Mechoulam R, Benito C, Romero J, Silva A, Guzmán M, Nataf S, Galve-Roperh I
The Journal of biological chemistry 2008 May 9;283(19):13320-9
The Journal of biological chemistry 2008 May 9;283(19):13320-9
Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment.
Claes A, Gambarota G, Hamans B, van Tellingen O, Wesseling P, Maass C, Heerschap A, Leenders W
International journal of cancer 2008 May 1;122(9):1981-6
International journal of cancer 2008 May 1;122(9):1981-6
Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.
Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O'Keefe RJ
Journal of cell science 2008 May 1;121(Pt 9):1455-65
Journal of cell science 2008 May 1;121(Pt 9):1455-65
Bone marrow-derived cells expressing Iba1 are constitutively present as resident tissue macrophages in the mouse cochlea.
Okano T, Nakagawa T, Kita T, Kada S, Yoshimoto M, Nakahata T, Ito J
Journal of neuroscience research 2008 Jun;86(8):1758-67
Journal of neuroscience research 2008 Jun;86(8):1758-67
Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.
Georges R, Nemer G, Morin M, Lefebvre C, Nemer M
Molecular and cellular biology 2008 Jun;28(12):4052-67
Molecular and cellular biology 2008 Jun;28(12):4052-67
Human ASH1 expression in prostate cancer with neuroendocrine differentiation.
Rapa I, Ceppi P, Bollito E, Rosas R, Cappia S, Bacillo E, Porpiglia F, Berruti A, Papotti M, Volante M
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jun;21(6):700-7
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jun;21(6):700-7
Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.
Hammoud Z, Tan B, Badve S, Bigsby RM
Endocrine-related cancer 2008 Jun;15(2):475-83
Endocrine-related cancer 2008 Jun;15(2):475-83
Expression of NANOG, but not POU5F1, points to the stem cell potential of primitive germ cells in neonatal pig testis.
Goel S, Fujihara M, Minami N, Yamada M, Imai H
Reproduction (Cambridge, England) 2008 Jun;135(6):785-95
Reproduction (Cambridge, England) 2008 Jun;135(6):785-95
Down-regulation of Notch signaling during corneal epithelial proliferation.
Djalilian AR, Namavari A, Ito A, Balali S, Afshar A, Lavker RM, Yue BY
Molecular vision 2008 Jun 5;14:1041-9
Molecular vision 2008 Jun 5;14:1041-9
HDAC4 inhibits cell-cycle progression and protects neurons from cell death.
Majdzadeh N, Wang L, Morrison BE, Bassel-Duby R, Olson EN, D'Mello SR
Developmental neurobiology 2008 Jul;68(8):1076-92
Developmental neurobiology 2008 Jul;68(8):1076-92
Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy.
Claes A, Schuuring J, Boots-Sprenger S, Hendriks-Cornelissen S, Dekkers M, van der Kogel AJ, Leenders WP, Wesseling P, Jeuken JW
Brain pathology (Zurich, Switzerland) 2008 Jul;18(3):423-33
Brain pathology (Zurich, Switzerland) 2008 Jul;18(3):423-33
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Nocito A, Dahm F, Jochum W, Jang JH, Georgiev P, Bader M, Graf R, Clavien PA
Cancer research 2008 Jul 1;68(13):5152-8
Cancer research 2008 Jul 1;68(13):5152-8
Applications of laser scanning cytometry in immunohistochemistry and routine histopathology.
Peterson RA, Krull DL, Butler L
Toxicologic pathology 2008 Jan;36(1):117-32
Toxicologic pathology 2008 Jan;36(1):117-32
Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway.
Steigen SE, Bjerkehagen B, Haugland HK, Nordrum IS, Løberg EM, Isaksen V, Eide TJ, Nielsen TO
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jan;21(1):46-53
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jan;21(1):46-53
Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma.
Jiang F, Zhang X, Kalkanis SN, Zhang Z, Yang H, Katakowski M, Hong X, Zheng X, Zhu Z, Chopp M
Photochemistry and photobiology 2008 Jan-Feb;84(1):128-37
Photochemistry and photobiology 2008 Jan-Feb;84(1):128-37
Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy.
Blansfield JA, Caragacianu D, Alexander HR 3rd, Tangrea MA, Morita SY, Lorang D, Schafer P, Muller G, Stirling D, Royal RE, Libutti SK
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):270-80
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):270-80
Chronic microcystin exposure induces hepatocyte proliferation with increased expression of mitotic and cyclin-associated genes in P53-deficient mice.
Clark SP, Ryan TP, Searfoss GH, Davis MA, Hooser SB
Toxicologic pathology 2008 Feb;36(2):190-203
Toxicologic pathology 2008 Feb;36(2):190-203
Regeneration with proliferation of the endothelium of cultured human donor corneas with extended postmortem time.
Slettedal JK, Lyberg T, Røger M, Beraki K, Ramstad H, Nicolaissen B
Cornea 2008 Feb;27(2):212-9
Cornea 2008 Feb;27(2):212-9
Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis.
Iulianella A, Sharma M, Durnin M, Vanden Heuvel GB, Trainor PA
Development (Cambridge, England) 2008 Feb;135(4):729-41
Development (Cambridge, England) 2008 Feb;135(4):729-41
Pulmonary arterial remodeling induced by a Th2 immune response.
Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G
The Journal of experimental medicine 2008 Feb 18;205(2):361-72
The Journal of experimental medicine 2008 Feb 18;205(2):361-72
An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis.
Vanheule E, Geerts AM, Van Huysse J, Schelfhout D, Praet M, Van Vlierberghe H, De Vos M, Colle I
International journal of experimental pathology 2008 Dec;89(6):419-32
International journal of experimental pathology 2008 Dec;89(6):419-32
Immunohistochemical and ultrastructural characterization of brain tumors in S100beta-v-erbB transgenic rats.
Yokoo H, Tanaka Y, Nobusawa S, Nakazato Y, Ohgaki H
Neuropathology : official journal of the Japanese Society of Neuropathology 2008 Dec;28(6):591-8
Neuropathology : official journal of the Japanese Society of Neuropathology 2008 Dec;28(6):591-8
Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development.
Pantalacci S, Prochazka J, Martin A, Rothova M, Lambert A, Bernard L, Charles C, Viriot L, Peterkova R, Laudet V
BMC developmental biology 2008 Dec 16;8:116
BMC developmental biology 2008 Dec 16;8:116
Foxg1 haploinsufficiency reduces the population of cortical intermediate progenitor cells: effect of increased p21 expression.
Siegenthaler JA, Tremper-Wells BA, Miller MW
Cerebral cortex (New York, N.Y. : 1991) 2008 Aug;18(8):1865-75
Cerebral cortex (New York, N.Y. : 1991) 2008 Aug;18(8):1865-75
Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.
Tong Z, Kunnumakkara AB, Wang H, Matsuo Y, Diagaradjane P, Harikumar KB, Ramachandran V, Sung B, Chakraborty A, Bresalier RS, Logsdon C, Aggarwal BB, Krishnan S, Guha S
Cancer research 2008 Aug 1;68(15):6100-8
Cancer research 2008 Aug 1;68(15):6100-8
Effect of n-3 polyunsaturated fatty acids on Barrett's epithelium in the human lower esophagus.
Mehta SP, Boddy AP, Cook J, Sams V, Lund EK, Johnson IT, Rhodes M
The American journal of clinical nutrition 2008 Apr;87(4):949-56
The American journal of clinical nutrition 2008 Apr;87(4):949-56
Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.
Zhang C, Lundgren K, Yan Z, Arango ME, Price S, Huber A, Higgins J, Troche G, Skaptason J, Koudriakova T, Nonomiya J, Yang M, O'Connor P, Bender S, Los G, Lewis C, Jessen B
Molecular cancer therapeutics 2008 Apr;7(4):818-28
Molecular cancer therapeutics 2008 Apr;7(4):818-28
Dearterialization of the liver causes intrahepatic cholestasis due to reduced bile transporter expression.
Hoekstra H, Tian Y, Jochum W, Stieger B, Graf R, Porte RJ, Clavien PA
Transplantation 2008 Apr 27;85(8):1159-66
Transplantation 2008 Apr 27;85(8):1159-66
Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.
Verma A, Guha S, Diagaradjane P, Kunnumakkara AB, Sanguino AM, Lopez-Berestein G, Sood AK, Aggarwal BB, Krishnan S, Gelovani JG, Mehta K
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Apr 15;14(8):2476-83
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Apr 15;14(8):2476-83
Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.
Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E
Cancer research 2008 Apr 1;68(7):2329-39
Cancer research 2008 Apr 1;68(7):2329-39
Prognostic significance of cell proliferation and apoptosis-regulating proteins in Epstein-Barr virus positive and negative pediatric Hodgkin lymphoma.
Aktaş S, Kargi A, Olgun N, Diniz G, Erbay A, Vergin C
Lymphatic research and biology 2007;5(3):175-82
Lymphatic research and biology 2007;5(3):175-82
The efficacy and safety of topically applied indigo naturalis ointment in patients with plaque-type psoriasis.
Lin YK, Wong WR, Chang YC, Chang CJ, Tsay PK, Chang SC, Pang JH
Dermatology (Basel, Switzerland) 2007;214(2):155-61
Dermatology (Basel, Switzerland) 2007;214(2):155-61
The intermediate filament nestin is highly expressed in normal human podocytes and podocytes in glomerular disease.
Perry J, Ho M, Viero S, Zheng K, Jacobs R, Thorner PS
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2007 Sep-Oct;10(5):369-82
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2007 Sep-Oct;10(5):369-82
The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.
Li Y, Tabatabai ZL, Lee TL, Hatakeyama S, Ohyama C, Chan WY, Looijenga LH, Lau YF
Human pathology 2007 Oct;38(10):1470-81
Human pathology 2007 Oct;38(10):1470-81
Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.
Louis H, Kakou A, Regnault V, Labat C, Bressenot A, Gao-Li J, Gardner H, Thornton SN, Challande P, Li Z, Lacolley P
American journal of physiology. Heart and circulatory physiology 2007 Oct;293(4):H2597-604
American journal of physiology. Heart and circulatory physiology 2007 Oct;293(4):H2597-604
Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of csk.
Honda K, Sakaguchi T, Sakai K, Schmedt C, Ramirez A, Jorcano JL, Tarakhovsky A, Kamisoyama H, Sakai T
Carcinogenesis 2007 Oct;28(10):2074-81
Carcinogenesis 2007 Oct;28(10):2074-81
Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.
Soucek L, Lawlor ER, Soto D, Shchors K, Swigart LB, Evan GI
Nature medicine 2007 Oct;13(10):1211-8
Nature medicine 2007 Oct;13(10):1211-8
The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties.
Blank-Porat D, Gruss-Fischer T, Tarasenko N, Malik Z, Nudelman A, Rephaeli A
Cancer letters 2007 Oct 18;256(1):39-48
Cancer letters 2007 Oct 18;256(1):39-48
SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.
Compagno D, Merle C, Morin A, Gilbert C, Mathieu JR, Bozec A, Mauduit C, Benahmed M, Cabon F
PloS one 2007 Oct 10;2(10):e1006
PloS one 2007 Oct 10;2(10):e1006
Post-acute response of 9L gliosarcoma to Photofrin-mediated PDT in athymic nude mice.
Zhang X, Jiang F, Kalkanis SN, Zhang Z, Hong X, Yang H, Chopp M
Lasers in medical science 2007 Nov;22(4):253-9
Lasers in medical science 2007 Nov;22(4):253-9
Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets.
Gallo R, Gambelli F, Gava B, Sasdelli F, Tellone V, Masini M, Marchetti P, Dotta F, Sorrentino V
Cell death and differentiation 2007 Nov;14(11):1860-71
Cell death and differentiation 2007 Nov;14(11):1860-71
Objective risk definition for endometrial lesion spectrum: a diagnostic algorithm.
Yilmaz I, Baloglu H, Haholu A, Berber U, Yildirim S, Ergur AR
Gynecologic oncology 2007 May;105(2):451-6
Gynecologic oncology 2007 May;105(2):451-6
p63 Is essential for the proliferative potential of stem cells in stratified epithelia.
Senoo M, Pinto F, Crum CP, McKeon F
Cell 2007 May 4;129(3):523-36
Cell 2007 May 4;129(3):523-36
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Okano J, Suzuki S, Shiota K
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract.
Kumar AP, Bhaskaran S, Ganapathy M, Crosby K, Davis MD, Kochunov P, Schoolfield J, Yeh IT, Troyer DA, Ghosh R
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 May 1;13(9):2784-94
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 May 1;13(9):2784-94
Snail silencing effectively suppresses tumour growth and invasiveness.
Olmeda D, Jordá M, Peinado H, Fabra A, Cano A
Oncogene 2007 Mar 22;26(13):1862-74
Oncogene 2007 Mar 22;26(13):1862-74
Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis.
Aguado T, Carracedo A, Julien B, Velasco G, Milman G, Mechoulam R, Alvarez L, Guzmán M, Galve-Roperh I
The Journal of biological chemistry 2007 Mar 2;282(9):6854-62
The Journal of biological chemistry 2007 Mar 2;282(9):6854-62
Ferumoxtran-10 enhancement in orthotopic xenograft models of human brain tumors: an indirect marker of tumor proliferation?
Kremer S, Pinel S, Védrine PO, Bressenot A, Robert P, Bracard S, Plénat F
Journal of neuro-oncology 2007 Jun;83(2):111-9
Journal of neuro-oncology 2007 Jun;83(2):111-9
Improved vascular engraftment and function of autotransplanted pancreatic islets as a result of partial pancreatectomy in the mouse and rat.
Johansson M, Jansson L, Carlsson PO
Diabetologia 2007 Jun;50(6):1257-66
Diabetologia 2007 Jun;50(6):1257-66
The properties of a mammary gland cancer stem cell.
Zucchi I, Sanzone S, Astigiano S, Pelucchi P, Scotti M, Valsecchi V, Barbieri O, Bertoli G, Albertini A, Reinbold RA, Dulbecco R
Proceedings of the National Academy of Sciences of the United States of America 2007 Jun 19;104(25):10476-81
Proceedings of the National Academy of Sciences of the United States of America 2007 Jun 19;104(25):10476-81
Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647.
Gendreau SB, Ventura R, Keast P, Laird AD, Yakes FM, Zhang W, Bentzien F, Cancilla B, Lutman J, Chu F, Jackman L, Shi Y, Yu P, Wang J, Aftab DT, Jaeger CT, Meyer SM, De Costa A, Engell K, Chen J, Martini JF, Joly AH
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jun 15;13(12):3713-23
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jun 15;13(12):3713-23
Microvascular proliferation in congenital vascular malformations of skin and soft tissue.
Meijer-Jorna LB, van der Loos CM, de Boer OJ, van der Horst CM, van der Wal AC
Journal of clinical pathology 2007 Jul;60(7):798-803
Journal of clinical pathology 2007 Jul;60(7):798-803
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Wong SC, Chan JK, Lo ES, Chan AK, Wong MC, Chan CM, Lam MY, Chan AT
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.
Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM
Genes & development 2007 Jul 15;21(14):1731-46
Genes & development 2007 Jul 15;21(14):1731-46
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence.
Li G, Vega R, Nelms K, Gekakis N, Goodnow C, McNamara P, Wu H, Hong NA, Glynne R
PLoS genetics 2007 Jan 5;3(1):e8
PLoS genetics 2007 Jan 5;3(1):e8
Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment.
Wiseman SM, Masoudi H, Niblock P, Turbin D, Rajput A, Hay J, Bugis S, Filipenko D, Huntsman D, Gilks B
Annals of surgical oncology 2007 Feb;14(2):719-29
Annals of surgical oncology 2007 Feb;14(2):719-29
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.
Estes JD, Wietgrefe S, Schacker T, Southern P, Beilman G, Reilly C, Milush JM, Lifson JD, Sodora DL, Carlis JV, Haase AT
The Journal of infectious diseases 2007 Feb 15;195(4):551-61
The Journal of infectious diseases 2007 Feb 15;195(4):551-61
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.
Smit LA, Hallaert DY, Spijker R, de Goeij B, Jaspers A, Kater AP, van Oers MH, van Noesel CJ, Eldering E
Blood 2007 Feb 15;109(4):1660-8
Blood 2007 Feb 15;109(4):1660-8
Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells.
Barraud P, He X, Zhao C, Ibanez C, Raha-Chowdhury R, Caldwell MA, Franklin RJ
The European journal of neuroscience 2007 Dec;26(12):3345-57
The European journal of neuroscience 2007 Dec;26(12):3345-57
Expression of glucose transporter protein-1 (Glut-1) in ocular surface squamous neoplasia.
Gurses I, Doganay S, Mizrak B
Cornea 2007 Aug;26(7):826-30
Cornea 2007 Aug;26(7):826-30
Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models.
Yang H, Chopp M, Zhang X, Jiang F, Zhang Z, Kalkanis S, Schallert T
Behavioural brain research 2007 Aug 22;182(1):42-50
Behavioural brain research 2007 Aug 22;182(1):42-50
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.
Aguado T, Romero E, Monory K, Palazuelos J, Sendtner M, Marsicano G, Lutz B, Guzmán M, Galve-Roperh I
The Journal of biological chemistry 2007 Aug 17;282(33):23892-8
The Journal of biological chemistry 2007 Aug 17;282(33):23892-8
Cellular responses to disruption of the permeability barrier in a three-dimensional organotypic epidermal model.
Ajani G, Sato N, Mack JA, Maytin EV
Experimental cell research 2007 Aug 15;313(14):3005-15
Experimental cell research 2007 Aug 15;313(14):3005-15
Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.
Wang W, Bergh A, Damber JE
The Prostate 2007 Aug 1;67(11):1238-46
The Prostate 2007 Aug 1;67(11):1238-46
Lymphoma-like lesion of the uterine cervix: report of 12 cases of a rare entity.
Ma J, Shi QL, Zhou XJ, Meng K, Chen JY, Huang WB
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007 Apr;26(2):194-8
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007 Apr;26(2):194-8
Nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder: a case report and review of published reports.
Neşe N, Kandiloğlu AR, Atesçi YZ
International journal of urology : official journal of the Japanese Urological Association 2007 Apr;14(4):365-7
International journal of urology : official journal of the Japanese Urological Association 2007 Apr;14(4):365-7
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB
Cancer research 2007 Apr 15;67(8):3853-61
Cancer research 2007 Apr 15;67(8):3853-61
Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model.
Borowsky AD, Dingley KH, Ubick E, Turteltaub KW, Cardiff RD, Devere-White R
Neoplasia (New York, N.Y.) 2006 Sep;8(9):708-15
Neoplasia (New York, N.Y.) 2006 Sep;8(9):708-15
Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.
Asikainen TM, Waleh NS, Schneider BK, Clyman RI, White CW
American journal of physiology. Lung cellular and molecular physiology 2006 Oct;291(4):L588-95
American journal of physiology. Lung cellular and molecular physiology 2006 Oct;291(4):L588-95
Bile salt toxicity aggravates cold ischemic injury of bile ducts after liver transplantation in Mdr2+/- mice.
Hoekstra H, Porte RJ, Tian Y, Jochum W, Stieger B, Moritz W, Slooff MJ, Graf R, Clavien PA
Hepatology (Baltimore, Md.) 2006 May;43(5):1022-31
Hepatology (Baltimore, Md.) 2006 May;43(5):1022-31
Effects of retrorsine on mouse hepatocyte proliferation after liver injury.
Zhou XF, Wang Q, Chu JX, Liu AL
World journal of gastroenterology 2006 Mar 7;12(9):1439-42
World journal of gastroenterology 2006 Mar 7;12(9):1439-42
Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment.
Riesterer O, Honer M, Jochum W, Oehler C, Ametamey S, Pruschy M
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jun 1;12(11 Pt 1):3518-24
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jun 1;12(11 Pt 1):3518-24
Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord.
Kitada M, Rowitch DH
Glia 2006 Jul;54(1):35-46
Glia 2006 Jul;54(1):35-46
Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma.
Nakamura N, Erickson LA, Jin L, Kajita S, Zhang H, Qian X, Rumilla K, Lloyd RV
Endocrine pathology 2006 Fall;17(3):213-23
Endocrine pathology 2006 Fall;17(3):213-23
Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma.
Nakamura N, Erickson LA, Jin L, Kajita S, Zhang H, Qian X, Rumilla K, Lloyd RV
Endocrine pathology 2006 Fall;17(3):213-23
Endocrine pathology 2006 Fall;17(3):213-23
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.
Ringshausen I, O'Shea CC, Finch AJ, Swigart LB, Evan GI
Cancer cell 2006 Dec;10(6):501-14
Cancer cell 2006 Dec;10(6):501-14
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
Ridgway J, Zhang G, Wu Y, Stawicki S, Liang WC, Chanthery Y, Kowalski J, Watts RJ, Callahan C, Kasman I, Singh M, Chien M, Tan C, Hongo JA, de Sauvage F, Plowman G, Yan M
Nature 2006 Dec 21;444(7122):1083-7
Nature 2006 Dec 21;444(7122):1083-7
A three-dimensional model of differentiation of immortalized human bronchial epithelial cells.
Vaughan MB, Ramirez RD, Wright WE, Minna JD, Shay JW
Differentiation; research in biological diversity 2006 Apr;74(4):141-8
Differentiation; research in biological diversity 2006 Apr;74(4):141-8
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide.
Tan M, Lan KH, Yao J, Lu CH, Sun M, Neal CL, Lu J, Yu D
Cancer research 2006 Apr 1;66(7):3764-72
Cancer research 2006 Apr 1;66(7):3764-72
Heparanase promotes growth, angiogenesis and survival of primary breast tumors.
Cohen I, Pappo O, Elkin M, San T, Bar-Shavit R, Hazan R, Peretz T, Vlodavsky I, Abramovitch R
International journal of cancer 2006 Apr 1;118(7):1609-17
International journal of cancer 2006 Apr 1;118(7):1609-17
Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex.
Siegenthaler JA, Miller MW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Sep 21;25(38):8627-36
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Sep 21;25(38):8627-36
Resin tissue microarrays: a universal format for immunohistochemistry.
Howat WJ, Warford A, Mitchell JN, Clarke KF, Conquer JS, McCafferty J
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005 Oct;53(10):1189-97
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005 Oct;53(10):1189-97
p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas.
Matos I, Dufloth R, Alvarenga M, Zeferino LC, Schmitt F
Virchows Archiv : an international journal of pathology 2005 Oct;447(4):688-94
Virchows Archiv : an international journal of pathology 2005 Oct;447(4):688-94
The kd/kd mouse is a model of collapsing glomerulopathy.
Barisoni L, Madaio MP, Eraso M, Gasser DL, Nelson PJ
Journal of the American Society of Nephrology : JASN 2005 Oct;16(10):2847-51
Journal of the American Society of Nephrology : JASN 2005 Oct;16(10):2847-51
Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer.
Renyi-Vamos F, Tovari J, Fillinger J, Timar J, Paku S, Kenessey I, Ostoros G, Agocs L, Soltesz I, Dome B
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7344-53
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Oct 15;11(20):7344-53
Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1.
Siegenthaler JA, Miller MW
Journal of neurochemistry 2005 Nov;95(3):902-12
Journal of neurochemistry 2005 Nov;95(3):902-12
Characterization and localization of side population cells in mouse skin.
Yano S, Ito Y, Fujimoto M, Hamazaki TS, Tamaki K, Okochi H
Stem cells (Dayton, Ohio) 2005 Jun-Jul;23(6):834-41
Stem cells (Dayton, Ohio) 2005 Jun-Jul;23(6):834-41
A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model.
Majeed N, Blouin MJ, Kaplan-Lefko PJ, Barry-Shaw J, Greenberg NM, Gaudreau P, Bismar TA, Pollak M
Oncogene 2005 Jul 7;24(29):4736-40
Oncogene 2005 Jul 7;24(29):4736-40
Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects.
Blanquicett C, Saif MW, Buchsbaum DJ, Eloubeidi M, Vickers SM, Chhieng DC, Carpenter MD, Sellers JC, Russo S, Diasio RB, Johnson MR
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Dec 15;11(24 Pt 1):8773-81
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Dec 15;11(24 Pt 1):8773-81
Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model.
Mack JA, Li L, Sato N, Hascall VC, Maytin EV
The Journal of biological chemistry 2005 Aug 19;280(33):29904-11
The Journal of biological chemistry 2005 Aug 19;280(33):29904-11
The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, Puzas JE, Birchmeier W, Hsu W
Development (Cambridge, England) 2005 Apr;132(8):1995-2005
Development (Cambridge, England) 2005 Apr;132(8):1995-2005
Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer.
Guha S, Eibl G, Kisfalvi K, Fan RS, Burdick M, Reber H, Hines OJ, Strieter R, Rozengurt E
Cancer research 2005 Apr 1;65(7):2738-45
Cancer research 2005 Apr 1;65(7):2738-45
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Supportive validation
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- Knockout of Ki-67 was achieved by CRISPR-Cas9 genome editing using LentiArray™ Lentiviral sgRNA (Product # A32042, Assay ID CRISPR955684_LV) and LentiArray Cas9 Lentivirus (Product # A32064). Immunofluorescence analysis was performed on HeLa wild type cells (panel a,d), HeLa Cas9 control cells (panel b,e) and HeLa Ki-67 KO cells (panel c, f). Cells were fixed, permeabilized, and labeled with Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520, 1:500 dilution), followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ Plus 488 (Product#A32790, 1:2000 dilution). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962), and Rhodamine Phalloidin (Product # R415, 1:300) was used for cytoskeletal F-actin (red) staining. Loss of signal (panel c,f) upon CRISPR mediated knockout (KO) confirms that antibody is specific to Ki-67 (green). The images were captured at 60X magnification.
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- Immunofluorescence analysis of Ki-67 was performed using 70% confluent log phase HeLa cells serum starved (SS) for 36 hours followed by serum release (SR) for 6 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:250 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790) at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing nuclear localization. Panel e represents the serum starved cells with reduced signal. Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.
Supportive validation
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- Formalin-fixed, paraffin-embedded human high grade invasive breast cancer tissue stained with MA5-14520 (1:400) to detect Ki-67, followed by a peroxidase-conjugated secondary reagent and DAB substrate. Data courtesy of the Innovators Program.
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- Formalin-fixed, paraffin-embedded human tonsil stained with Ki-67 using peroxidase-conjugate and AEC. Note nuclear staining of proliferating cells.
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- Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human tonsil tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.
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- Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human breast tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.
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- Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.
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- Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.
Supportive validation
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- Flow cytometry analysis of Ki-67 was done on MCF7 cells. Cells were fixed with 70% ethanol for 10 minutes, permeabilized with 0.25% Triton™ X-100 for 20 minutes, and blocked with 5% BSA for 30 minutes at room temperature. Cells were labeled with Ki-67 Rabbit Monoclonal Antibody (MA514520, red histogram) or with rabbit isotype control (yellow histogram) at 3-5 ug/million cells in 2.5% BSA. After incubation at room temperature for 2 hours, the cells were labeled with Alexa Fluor® 488 Goat Anti-Rabbit Secondary Antibody (A11008) at a dilution of 1:400 for 30 minutes at room temperature. The representative 10,000 cells were acquired and analyzed for each sample using an Attune® Acoustic Focusing Cytometer. The purple histogram represents unstained control cells and the green histogram represents no-primary-antibody control.
Supportive validation
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- Fig. 2 Col2-Cre: Tsc1 fl/fl metatarsals have a growth advantage ex vivo . ( A ) Growth curves of metatarsals collected from three-day old mice and cultured for six days ex vivo . ( B ) Metatarsals were collected immediately before culture or after one day in culture (contralateral controls), then stained for pS6, Ki67 (immunohistochemistry) or COL10A1 ( in situ hybridization). For Ki67 staining, the region directly above the hypertrophic zone is expanded (pink box). For COL10A1 staining, the yellow dashed line denotes the border between the cartilage and the primary spongiosa. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.) Fig. 2
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- Figure 3 RSPO2 Promotes Midbrain Dopaminergic Neurons Differentiation in Primary Cultures (A) Schematic representation of the mouse primary cell culture protocol. (B) Quantification of the total cell numbers (DAPI) and proportion of neurons (betaIII-tubulin/DAPI) normalized to control (Vehicle). (C) Quantification of ongoing cell death, measured by active caspase-3 ICC (aC3 + /DAPI), showed no difference compared with Vehicle. (D) Quantification of KI67 ICC (KI67 + /DAPI) showed no difference compared with Vehicle. (E) ICC staining showing and increase in TH + neurons compared with DAPI after RSPO2 treatment, but not RSPO1 or SPON1. Scale bars, 50 mum. (F) Quantification of postmitotic cells in the DA lineage, measured by NR4A2 ICC, showed no difference compared with Vehicle. (G) Bar plots showing that RSPO2 treatment increases the total number of TH + cells (TH/DAPI), compared with control (Vehicle). (H) Normalized ratio of TH + cells/NR4A2 + cells revealed an increase in the proportion of postmitotic dopaminergic cells (NR4A2 + ) becoming mDA neurons (TH + ). (I) ICC staining of cells treated with various Wnt signaling pathway modifiers, stained with TH and betaIII-tubulin. Scale bars, 50 mum. (J) Quantification of TH + cells in various treatments from (I) as compared with Vehicle. All data normalized to control (Vehicle) presented as means +- SEM. n = 3, t test; * p < 0.05, ** p < 0.01. See also Figure S3 .
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- Figure 4 RSPO2 Promotes the Dopaminergic Differentiation of Mouse ESCs (A) Cartoon showing the protocol for the differentiation of mouse ESCs into mDA neurons and the time line (d, days) of spondin treatment, between days 5 and 11. (B) Quantification of proliferation (KI67) in areas undergoing neurogenesis (betaIII-tubulin + ) as assessed by ICC, normalized to control. (C) Quantification of ongoing cell death by active caspase-3 (aC3) ICC in betaIII-tubulin + areas. (D) ICC for NR4A2 and betaIII-tubulin after 14 days in vitro and bar plots showing no difference in the number of NR4A2 + cells per betaIII-tubulin area. Scale bars, 50 mum. (E) ICC staining for TH and betaIII-tubulin after 14 days in vitro in vehicle-, SPON1-, and RSPO2-treated cultures. Scale bars, 50 mum. (F) The number of TH + cells per betaIII-tubulin area by ICC, normalized to control, increased by RSPO2 treatment and decreased by SPON1. (G) The proportion of NR4A2 + cells that become TH + increased by RSPO2 treatment and decreased by SPON1. All data normalized to control (Vehicle) presented as means +- SEM. n = 3, t test; * p < 0.05, ** p < 0.01, *** p < 0.001.
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- Figure 6 Decreased parietal cells and increased cell proliferation in Helicobacter -infected Lgr5-Cre;Bmpr1a flox-flox mice. One- to 2-month-old Lgr5-Cre mice and Lgr5-Cre;Bmpr1a flox-flox mice were treated with 1 intraperitoneal injection of tamoxifen (0.1 mg/g body weight) and inoculated with H felis 2 months after tamoxifen. Animals were analyzed 3 months after inoculation and 5 months after tamoxifen injection. Paraffin sections of the lesser curvature of Lgr5-Cre mice and of Lgr5-Cre;Bmpr1a flox-flox mice, in the presence and absence of H felis (H. f.), were stained with an ( A ) anti-H + ,K + -ATPase alpha-subunit primary antibody and an Alexa 488-conjugated secondary antibody (green), and with an ( C ) anti-Ki67 primary antibody and an Alexa 555-conjugated secondary antibody (red). Scale bars : 100 mum. Bars represent the number of ( B ) H + ,K + -ATPase alpha-subunit and of ( D ) Ki67-positive cells detected in Lgr5-Cre mice and in Lgr5-Cre;Bmpr1a flox-flox mice in the presence and absence of H felis . Values are shown as means +- SE. Numbers in parenthesis indicate the number of animals used in each group. * P < .05 vs Lgr5-Cre mice. ** P < .05 vs Lgr5-Cre;Bmpr1a flox-flox mice. DAPI, 4'6-diamidino-2-phenylindole.