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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA3-110 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SSTR3 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA3-110 detects the Somatostatin Receptor 3 in human samples. PA3-110 has been used successfully in Western blot, immunocytochemistry, and immunohistochemistry procedures. In Western blot analysis of SSTR3 transfected HEK-293 cells this antibody detects a ~60-70 kDa protein representing SSTR3. The PA3-110 immunogen is a synthetic peptide corresponding to residues C Q(385) E R P P S R V A(393) of human SSTR3.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- Conc. Not Determined
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Neuroblastoma xenograft models demonstrate the therapeutic potential of (177)Lu-octreotate.
Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines.
Prominin-1 allows prospective isolation of neural stem cells from the adult murine hippocampus.
Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy.
Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies.
Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies.
Romiani A, Spetz J, Shubbar E, Lind DE, Hallberg B, Palmer RH, Forssell-Aronsson E
BMC cancer 2021 Aug 25;21(1):950
BMC cancer 2021 Aug 25;21(1):950
Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines.
Li Z, Jiang X, Chen P, Wu X, Duan A, Qin Y
Oncology letters 2018 Sep;16(3):4033-4042
Oncology letters 2018 Sep;16(3):4033-4042
Prominin-1 allows prospective isolation of neural stem cells from the adult murine hippocampus.
Walker TL, Wierick A, Sykes AM, Waldau B, Corbeil D, Carmeliet P, Kempermann G
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Feb 13;33(7):3010-24
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Feb 13;33(7):3010-24
Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy.
Mundschenk J, Unger N, Schulz S, Höllt V, Schulz S, Steinke R, Lehnert H
The Journal of clinical endocrinology and metabolism 2003 Nov;88(11):5150-7
The Journal of clinical endocrinology and metabolism 2003 Nov;88(11):5150-7
Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies.
Kulaksiz H, Eissele R, Rössler D, Schulz S, Höllt V, Cetin Y, Arnold R
Gut 2002 Jan;50(1):52-60
Gut 2002 Jan;50(1):52-60
Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies.
Kulaksiz H, Eissele R, Rössler D, Schulz S, Höllt V, Cetin Y, Arnold R
Gut 2002 Jan;50(1):52-60
Gut 2002 Jan;50(1):52-60
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SSTR3 in human pancreatic islands using Product # PA3-110.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig. 5 IHC staining for SSTR1-5 in CLB-BAR, CLB-GE and IMR-32. Tissues were stained with H&E prior to IHC staining for SSTR1-5. For positive control, tissue from human cerebellum was applied for SSTR1 and SSTR3-5, and tissue from human small intestinal NET was applied for SSTR2. Bar equals 50 mum
