ANXA8L1

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Apr 2014]

Description

Annexin A8 like 1

Tissue specificity

Group enriched (esophagus, skin , vagina)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

10 (46375627 - 46391784)

Ensembl ID

ENSG00000264230  (ver. 103.38)

Orthologs

-

UniProt

Q5VT79

neXtProt

NX_Q5VT79

Human splice variants

Protein structure