BS6401

antibody from Bioworld Technology, Inc
Targeting: MEF2C
Provider product page for BS6401
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6401 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MEF2C (phospho S396) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human MEF2C around the phosphorylation site of Serine 396.
Description
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MEF2C protein structure - BS6401 shown in red.