Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 11622-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11622-1-AP, RRID:AB_10216360
- Product name
- DOCK8 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DOCK8 antibody (Cat. #11622-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ultra-high static magnetic fields cause immunosuppression through disrupting B-cell peripheral differentiation and negatively regulating BCR signaling.
DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus.
CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation.
Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing.
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells.
Gu H, Fu Y, Yu B, Luo L, Kang D, Xie M, Jing Y, Chen Q, Zhang X, Lai J, Guan F, Forsman H, Shi J, Yang L, Lei J, Du X, Zhang X, Liu C
MedComm 2023 Oct;4(5):e379
MedComm 2023 Oct;4(5):e379
DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus.
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, Matsuyama H, Doi A, Tarui M, Izumikawa M, Kimura M, Fujita Y, Satonaka C, Horiuchi T, Matsubara T, Oribe M, Yamane T, Kagawa H, Li QZ, Mizuno K, Mukai Y, Murakami K, Enya T, Tsukimoto S, Hakata Y, Miyazawa M, Shiozawa K
iScience 2022 Jan 21;25(1):103537
iScience 2022 Jan 21;25(1):103537
CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation.
Yang L, Li N, Yang D, Chen A, Tang J, Jing Y, Kang D, Jiang P, Dai X, Luo L, Chen Q, Chang J, Liu J, Gu H, Huang Y, Chen Q, Li Z, Zhu Y, Miller H, Chen Y, Qiu L, Mei H, Hu Y, Gong Q, Liu C
Cell death and differentiation 2021 Sep;28(9):2616-2633
Cell death and differentiation 2021 Sep;28(9):2616-2633
Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing.
Qu H, Miao T, Wang Y, Tan L, Huang B, Zhang L, Liu X, Long M, Zhang R, Liao X, Gong X, Wang J, Xiong X, Liu J, Li X, Yu J, Yang G, Zhu Z, Zheng H, Zheng Y
Diabetes 2021 May;70(5):1170-1184
Diabetes 2021 May;70(5):1170-1184
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S
Nature immunology 2016 Dec;17(12):1361-1372
Nature immunology 2016 Dec;17(12):1361-1372
CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells.
Wang SJ, Cui HY, Liu YM, Zhao P, Zhang Y, Fu ZG, Chen ZN, Jiang JL
Oncotarget 2015 Jan 1;6(1):243-57
Oncotarget 2015 Jan 1;6(1):243-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 11622-1-AP(DOCK8 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 11622-1-AP(DOCK8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DOCK8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DOCK8. This antibody recognizes human,mouse,rat antigen. The DOCK8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.