Antibody data

Product number
BS2282
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2282, RRID:AB_1662819
Product name
TFIIA Ï« (E311) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS2282
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 300-350 of Human TFIIA-Ï«.
Description
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-Ï«, TFIIA-ÉÇ and TFIIA-ÎÛ, and it interacts with both TBP and a TAF (TBP-associated factor). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -