orb2635070

antibody from Biorbyt
Targeting: GTF2A1 TFIIA
Provider product page for orb2635070
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2635070 - Provider product page
Provider
Biorbyt
Product name
GTF2A1 Antibody / TFIIA
Antibody type
Monoclonal
Description
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in formation of the preinitiation complex (PIC) which contains several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-, all of which associate with both TBP and TAF (TBP-associated factor). TFIIA functions to stabilize the interaction between TFIID and DNA by binding directly to TBP and the DNA (at the TATA box), thus forming a TBP/TFIIA/TATA complex which mediates the transcriptional output of a gene.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-GTF2A1-1F2
Vial size
20 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
GTF2A1 protein structure - orb2635070 shown in red.