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- References [2235]
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- Western blot [1]
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- Immunoprecipitation [1]
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- Product number
- 18420-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18420-1-AP, RRID:AB_10694431
- Product name
- P62,SQSTM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P62,SQSTM1 antibody (Cat. #18420-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation.
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination.
Circular RNA circPLXNC1 functions as an inhibitor of senescence by regulating autophagy in osteoarthritis.
SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy.
Aspergillus fumigatus Gliotoxin Inhibits LC3-Associated Phagocytosis in Macrophages in a Calcium-Dependent Manner.
Exosomal lncRNA FENDRR Orchestrates Immune Remodelling and Ferroptosis in the Comorbidity of Lung Cancer and Type 1 Myocardial Infarction.
C9orf72-ALS mutation drives basal mitophagy impairments in iNeurons.
Ginsenoside Rg3 Mitigates LPS-Induced Injury in Human Bronchial Epithelial Cells by Restoring Autophagic Flux and Inhibiting the TLR4/NF-κB-Mediated Inflammatory Response.
Bitter gourd peptides (BG) alleviate lupus progression in mice through regulation of miR-146a/BRD4 axis in macrophages.
Nanosized silicon nitride promotes vascularized osteogenesis through regulating the endothelial adherens junctions via the FRMD6/VE-cadherin pathway.
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
RNA-binding motif protein 15 promotes gastric cancer growth and drug resistance via USP10-mediated deubiquitination and stabilization of nuclear NRF2.
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
vtRNA1-1/p62 regulates macrophages autophagy in ankylosing spondylitis.
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Ginsenoside Rg1 mitigates sepsis-associated acute respiratory distress syndrome by promoting autophagy through the Prdx1-PTEN/PI3K/AKT pathway.
Ixazomib triggers autophagic degradation of MUC5AC/integrin-β4 and inhibits non-small cell lung cancer progression.
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism.
Ajugoside Promotes the Repair of Osteoporotic Bone by Inducing Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells.
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis.
Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
Restricting intracellular Salmonella proliferation by coordinating p-TBK1 mediated mitophagy and xenophagy.
TIGAR promotes osteogenic differentiation and ameliorates glucocorticoid-induced osteoporosis via autophagy-Nrf2-ROS axis.
Thymoquinone attenuates poly(I:C)-induced cellular stress via PKR/ATF4/CHOP signaling and autophagy modulation in human alveolar epithelial cells.
Translation of expanded CGG repeats in LRP12 associated oculopharyngodistal myopathy.
Polystyrene Nanoplastics induced placental toxicology by activating Keap1-mediated ferroptosis via METTL3-dependent m6A methylation.
Resveratrol Attenuates Liver Inflammation in Non-Alcoholic Fatty Liver Disease by Activating PINK1-Mediated Mitophagy.
Didymin alleviates neuropathic pain by targeting RKIP-mediated NF-κB/NLRP3 crosstalk to inhibit pyroptosis and neuroinflammation.
Annexin A1 triggers autophagy to orchestrate radioiodine resistance in thyroid cancer via upregulating HMGB1.
Cannabigerol Reduces Lipid Peroxidation Influencing Oxidative Stress and Inflammation Signaling Pathways in Melanocytes Exposed to UVA Radiation.
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein.
A germline-specific vesicular structure licenses mRNA activation during spermiogenesis and is hijacked in gastric cancer.
Overexpression of As3mt Attenuates Sodium Arsenite Induced Ferritinophagy and Hepatic Lipid Accumulation in Mice.
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Nuclear Localization of Effector BPE159: A Pivotal Mechanism for Intracellular Persistence of Brucella by Hampering Host Autophagy.
Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury.
Lipotoxic hepatocyte-derived UBQLN1-enriched small extracellular vesicles activate hepatic stellate cells to promote hepatic fibrosis.
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Glaesserella parasuis serotype 5 disrupts the swine respiratory epithelial barrier via NBR1-mediated selective autophagic degradation of Claudin-1.
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy.
Usenamine a potentiates anti-CRC activity of sorafenib by inducing autophagy and inhibiting YAP pathway through targeting SOD2.
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Bergapten ameliorates osteoarthritis progression by inhibiting the PI3K/AKT/mTOR pathway to activate mitophagy and suppress pyroptosis.
A foam cell-targeted lipophagy restoration strategy stabilizes vulnerable atherosclerotic plaques.
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy.
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Selaginella Tamariscina extract reduces UVA-induced skin photodamage via regulating apoptosis and autophagy by AKT phosphorylation.
Parkin protects against traumatic brain injury through regulating mitochondrial quality control.
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.
Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux.
Opn3 Drives Blue-Light-Induced Reduction in Lipid Droplets and Antiviral Defense.
Targeting endolysosomal acidification inhibits poxvirus entry and replication.
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Outer membrane vesicles secreted by avian pathogenic Escherichia coli promote its survival within macrophages and systemic infection by inducing endoplasmic reticulum stress-mediated autophagy flux blockade.
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Acacetin Attenuates Lysophosphatidylcholine-Induced Vascular Smooth Muscle Cell Injury via Sirt1-Nrf2/p62 Signaling Axis.
rIL-22 Alleviates Severe Acute Pancreatitis and Secondary Multiple Organ Injury Induced by Caerulein in Mice.
tRNA m(2)G methyltransferase complex THUMPD3-TRMT112 promotes pancreatic cancer progression and autophagy via modulating TFEB translation.
In Situ Reprogramming of Senescent Microenvironment via Augmentation of Endogenous Senolytic Actions for Advanced Atherosclerosis Management.
Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy.
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
STING deficiency alleviates ischemia-reperfusion injury via JAK2/STAT3-mediated macrophage polarization and autophagy.
Heme oxygenase 1 (HO-1) is a drug target for reversing cisplatin resistance in non-small cell lung cancer.
Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following Porphyromonas endodontalis Infection.
Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.
STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma.
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
SIX2-Mediated Microglial M2 Polarization and Exosomal miR-3470b Delivery Protect Dopaminergic Neurons in Parkinson's Disease.
CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy.
Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.
Cannabidiol alleviates methamphetamine-induced autophagy and oxidative stress by suppressing sigma 1 receptor expression.
MSMP promotes an aberrant phenotype of fibroblast-like synoviocytes in rheumatoid arthritis by blocking autophagy via the RUNX1/GPR137B axis.
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin.
SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis.
Neural stem cell-derived exosomal PA2G4 induces ANXA2 degradation to promote mitophagy and alleviate neuronal oxidative stress in cerebral ischemia/reperfusion.
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
Melatonin ameliorates copper accumulation-induced cognitive impairment in Wilson disease via activation of the SIRT3/FOXO3α signaling pathway.
Negative feedback regulation of STING signaling by TAX1BP1-directed Golgiphagy.
miR-17-5p inhibits classical swine fever virus replication by targeting the PKD2-regulated AMPK/mTOR autophagy pathway.
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.
MeCP2 dysregulation inhibits mitophagy and impairs neural development in cortical organoids.
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Oligodendrocyte Inclusion Pathology in Fragile X-Associated Tremor/Ataxia Syndrome.
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
ANKFY1 suppresses PDCoV replication by degrading viral nsp8 protein via p62-dependent selective autophagy.
TNFAIP8 targets ATG3 to regulate autophagy and participate in the molecular mechanism of ankylosing spondylitis.
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.
Emerging Alternaria Toxins Drive LX-2 Cells Transdifferentiation into Myofibroblasts for Liver Fibrosis and CotA Detoxification.
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity.
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Deficiency in beclin1 alleviates doxorubicin-induced liver injury through inhibiting ferroptosis and autophagy.
STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates.
Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
USP2 Attenuates Spermatogenic Cell Apoptosis Via PINK1/Parkin-Dependent Mitophagy in Varicocoele: A Functional Study.
T-2 toxin induces ER stress-dependent liver injury via mitophagy-mediated ER-phagy suppression: Berbamine blocks SNARE complex for hepatoprotection.
EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy.
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Endotoxin tolerance inhibits NLRP3 inflammasome activation in macrophages of septic mice by restoring autophagic flux through TRIM26.
Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxin.
Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy.
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
The aggrephagy-related gene TUBA1B influences clinical outcomes in glioma patients by regulating the cell cycle.
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels.
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction.
ADSC-EVs Activate Autophagy Via the AKT/FOXO1 Pathway to Inhibit Tendon Fibrosis.
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation.
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Promoter polymorphism rs510432 in ATG5 affects the susceptibility of noise-induced hearing loss by altering the binding of C/EBPβ.
miR-545-x regulates hypoxia-induced proliferation, apoptosis and autophagy of yak coronary smooth muscle cells by antagonizing DNA damage inducible transcript 4.
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
PINK1-mediated mitochondrial autophagy protects lens epithelial cells by reducing ROS and apoptosis.
R406 and its structural analogs reduce SNCA/α-synuclein levels via autophagic degradation.
Resveratrol ameliorates streptozotocin induced renal inflammation and promotes autophagy by mediating the SphK1 pathway via Sirt1 in Wistar rats.
EPOR activation attenuates colitis via enhancing LC3B-dependent apoptotic cell clearance.
Energy metabolism disturbance induced by atorvastatin exposure on yellowstripe goby (Mugilogobius chulae) larvae based on transcriptome and metabolome analysis.
Tectorigenin attenuates myocardial damage by doxorubicin-induced ferroptosis by activating the p62-Keap1-Nrf2/HO-1/GPX4 axis.
Magnolin Promotes PINK1-Parkin-mediated Mitophagy in Diffuse Large B-cell Lymphoma Cells via PPAR-γ Pathway.
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
Melatonin attenuates ischemia-reperfusion-induced acute kidney injury by regulating abnormal autophagy and pyroptosis through SIRT1-mediated p53 deacetylation.
Type B Fibers: A Novel Ultrastructural Biomarker for Cognitive Impairment in Neuronal Intranuclear Inclusion Disease.
LINC01018 attenuates hepatic lipid accumulation by inducing autophagy via DHX9 pathway in alcohol-associated liver disease.
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
IRGM Inhibits the AKT/mTOR Signaling Pathway by Interacting with TRIM21 to Alleviate Sepsis-Induced Acute Lung Injury.
SNX10 enhances HCoV-OC43 infection by facilitating viral entry and inhibiting virus-triggered autophagy.
Effect of activated autophagy on an animal model of vestibular migraine-like attacks.
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
ER‑α36 knockdown is associated with lysosomal dysfunction and proliferation inhibition in liver cancer cells.
The Matrine Derivative MASM Alleviates LPS-Induced Depressive-Like Behavior in Mice by Modulating Hippocampal Inflammation, Oxidative Stress, and Autophagy.
Asparaginase and Autophagy Inhibitors Effectively Remove Senescent Cells by Synergistically Limiting Asparagine Supply.
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Berberine partially ameliorates cardiolipotoxicity in diabetic cardiomyopathy by modulating SIRT3-mediated lipophagy to remodel lipid droplets homeostasis.
Wogonin modulates macrophage polarization and inflammatory signaling through the LSD1-p65 axis to alleviate osteoarthritis.
Artificial intelligence combined with affinity chromatography discover that 7-Epitaxol promotes autophagy in NSCLC cells by interacting with EGFR: Discovery of novel EGFR antagonist based on DL and CMC.
LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney disease.
The AKT-USP15 axis modulates autophagy in MPP(+)-induced Parkinson's disease model of SN4741 cells.
Yogurt alleviates alcohol-induced hepatocyte pyroptosis and inflammation via autophagy/P62/Nrf2/ROS/NLRP3 pathway.
Novel Isolongifolenone-Based Caprolactam Derivatives as Potential Anticancer Agents via the p53/mTOR/Autophagy Pathway.
Uncovering the Regulatory Role of Proteins in EBSS-Induced Autophagy Using RNA-Seq Analysis.
Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma.
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
Bisphenol A Disrupts Spermatogenesis via Excessive Mitophagy-Driven Ferroptosis.
The WW domain presents a promising target for the development of PCIF1 agonists in the treatment of glioma.
Inhibition of glutamine synthetase enhances hepatocellular carcinoma radiosensitivity through ROS-induced excessive mitophagy.
Lipidomics Revealed the Suppression of 5-PAHSA from Human Milk on Macrophage Foam Cell Formation.
HIF-1α Activates Mitophagy through BNIP3 to Inhibit IPEC-J2 Apoptosis under Heat Stress.
Curcumin's dual effect on pyroptosis and autophagy in metabolic- associated fatty liver disease: a potential therapeutic strategy.
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
CORM-3 mitigates osteoarthritis by anti-inflammation and enhancing autophagy via inhibiting MAPK and mTOR pathways.
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Inhibition of DYRK1A can alleviate MPTP/MPP(+)-induced neuronal apoptosis and mitochondrial damage.
Development of an efficient mice model of cancer-associated cardiac cachexia.
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues.
Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathway.
Cadmium-mediated autophagy increases ferroptosis of ovarian granulosa cells.
NFE2L2 protects against Sorafenib-induced Ferroptosis and cardiotoxicity by activating the HO1/ferritin pathway.
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
A novel GM-CSF-encoding oncolytic adenovirus induces profound autophagy and promotes viral replication to enhance anti-tumor efficacy.
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
CERKL Reduced PI3P/Autophagy to Promote Pancreatic Cancer.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane.
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy.
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Ferroptosis mediated by ferritinophagy is involved in liver injury caused by sepsis.
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression.
Matrine activates high xenophagy to inhibit enterovirus replication.
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Semen Ziziphi Spinosae affects circadian rhythm of the cAMP signaling pathway by BMAL1-clockophagy to improve sleep disorders in depression.
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Glaucocalyxin A induces autophagy-mediated ferroptosis by targeting PRDX1 and TXNRD1 proteins in non-small cell lung cancer.
[Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway].
Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.
Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis.
GLP-1/GIP dual agonist tirzepatide alleviates mice model of Parkinson's disease by promoting mitochondrial homeostasis.
AICAr Inhibition of cardiomyocyte autophagy promotes p62-dependent NRF2 expression and protection against doxorubicin toxicity.
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway.
An effector of phosphatidylinositol 3-kinase activity promotes Rickettsia rickettsii virulence by enhancing autophagy.
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis.
S-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy.
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
Acetylation of Hsc70 at K512 inhibits goat ovarian granulosa cell senescence by restoring chaperone-mediated autophagy.
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis.
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
Nicotine Ameliorates α-Synuclein Preformed Fibril-Induced Behavioral Deficits and Pathological Features in Mice.
7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death.
NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke.
Liensinine overcomes EGFR-TKI resistance in lung adenocarcinoma through DRP1-mediated autophagy.
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
LAMP3 exacerbates autophagy-mediated neuronal damage through NF-kB in microglia.
Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low-Temperature Photothermal Therapy via Targeting HSP90-TXNDC9 Interactions.
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Rab GTPases are evolutionarily conserved signals mediating selective autophagy.
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
αSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis.
Calpain1 inhibition enhances autophagy-lysosomal pathway and ameliorates tubulointerstitial fibrosis in Nephronophthisis.
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Dihydroartemisinin alleviates diethylnitrosamine-induced hepatocarcinogenesis by targeting a novel MAZ/TRIM50 axis.
RAB18 deficiency disrupts lipid metabolism and autophagy in mice.
Long non-coding RNA HOXA11-AS inhibits apoptosis, induces proliferation, and promotes autophagy via the miR-214-3p/ATG12 axis in acute T lymphoblastic leukemia.
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease.
SRSF1-mediated alternative splicing regulates bladder cancer progression and cisplatin sensitivity through HIF1A/BNIP3/mitophagy axis.
Autophagy and exosome dynamics in Radiation-Induced pulmonary fibrosis: the critical role of TRIB3.
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Effects of Aerobic Exercise on Irisin and Skeletal Muscle Autophagy in ApoE(-/-) Mice.
Lysionotin promoted apoptosis of hepatocellular carcinoma cells via inducing autophagy.
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.
Mechanism of arsenic regulation of mitochondrial damage and autophagy induced synaptic damage through SIRT1 and protective effect of melatonin in HT22 cell.
Analysis of the key signaling pathway of baicalin that induces autophagy in papillary thyroid cancer via an optical resonator.
Hsp90 and HIF-1α regulate mitophagy by promoting BNIP3 expression in renal ischemia-reperfusion injury.
Caloric restriction exacerbates renal post-ischemic injury and fibrosis by modulating mTORC1 signaling and autophagy.
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation.
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
NLRX1 deficiency exacerbates skin inflammation in atopic dermatitis by disrupting mitophagy.
Rpl12 is a conserved ribophagy receptor.
Bisdemethoxycurcumin mitigates traumatic brain injury in rats by modulating autophagy and oxidative stress via heat shock protein 90 alpha family class A member 1-mediated nuclear translocation of transcription factor EB.
Dehydroervatamine as a promising novel TREM2 agonist, attenuates neuroinflammation.
USP13 facilitates a ferroptosis-to-autophagy switch by activation of the NFE2L2/NRF2-SQSTM1/p62-KEAP1 axis dependent on the KRAS signaling pathway.
ATP6V1D drives hepatocellular carcinoma stemness and progression via both lysosome acidification-dependent and -independent mechanisms.
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione mediates the effect of ROS-enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer.
SIRT5-mediated GLS and GDH desuccinylation attenuates the autophagy of bovine mammary epithelial cells induced by ammonia.
TFE3-mediated neuroprotection: Clearance of aggregated α-synuclein and accumulated mitochondria in the AAV-α-synuclein model of Parkinson's disease.
Microglia-Derived Interleukin-6 Triggers Astrocyte Apoptosis in the Hippocampus and Mediates Depression-Like Behavior.
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Costunolide Ameliorates the Methylmalonic Acidemia Via the PINK1/Parkin Pathway.
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Poria cocos-Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation.
Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy.
Regulation on mitophagy in adenomyosis by Guizhi Fuling Wan.
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
DKS26 Alleviates Ischemia-Reperfusion Injury-Induced Acute Kidney Injury by Stabilizing Vitamin D Receptors to Inhibit the Inflammatory Pathway of NF-κB P65.
Rapamycin mitigates neurotoxicity of fluoride and aluminum by activating autophagy through the AMPK/mTOR/ULK1 pathway in hippocampal neurons and NG108-15 cells.
FBXO45 restricts HIV-1 replication by inducing SQSTM1/p62-mediated autophagic degradation of Tat.
Exploring the effect of chlorogenic acid on oxidative stress and autophagy in dry eye mice via the AMPK/ULK1 pathway.
Lysophosphatidylcholine promoting α-Synuclein aggregation in Parkinson's disease: disrupting GCase glycosylation and lysosomal α-Synuclein degradation.
HTLV-1 Tax induces PINK1-Parkin-dependent mitophagy to mitigate activation of the cGAS-STING pathway.
Characterization and neurotherapeutic evaluation of venom polypeptides identified from Vespa magnifica: The role of Mastoparan-M in Parkinson's disease intervention.
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation.
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation.
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
HN1 Functions in Protein Synthesis Regulation via mTOR-RPS6 Axis and Maintains Nucleolar Integrity.
Accumulation of microtubule-associated protein tau promotes hepatocellular carcinogenesis through inhibiting autophagosome-lysosome fusion.
SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression.
Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Reduced store operated calcium entry contributes to autophagy mediated escape of prostate cancer to oxaliplatin treatment.
Photobiomodulation regulates inflammation and autophagy in spinal cord injury through NLRP3/Caspase-1/IL-1β pathway by targeting TLR2.
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Antitumor/anti-inflammatory effects/tissue healing as an all-in-one therapeutic strategy for nasopharyngeal carcinoma.
Polypyrrole-ferric phosphate-methotrexate nanoparticles enhance apoptosis/ferroptosis of M1 macrophages via autophagy blockage for rheumatoid arthritis treatment.
β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1.
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets.
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
Exposure of the human placental primary cells to nanoplastics induces cytotoxic effects, an inflammatory response and endocrine disruption.
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome.
Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4-regulated ferroptosis.
ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.
Adipose mesenchymal stem cell-derived extracellular vesicles regulate PINK1/parkin-mediated mitophagy to repair high glucose-induced dermal fibroblast senescence and promote wound healing in rats with diabetic foot ulcer.
Inhibition of CDC27 O-GlcNAcylation coordinates the antitumor efficacy in multiple myeloma through the autophagy-lysosome pathway.
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway.
Metformin Improves Palmitate-Induced Follicular Granulosa Cell Dysfunction by Activating ULK1-Mediated Autophagy.
TRIM21-driven K63-linked ubiquitination of RBM38c, as a novel interactor of BECN1, contributes to DNA damage-induced autophagy.
Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy.
Extracellular GMFB activates the non-canonical FAS-FAF1 pathway to induce lysosomal dysfunction in early diabetic retinopathy.
Nuclear p62/SQSTM1 facilitates ubiquitin-independent proteasomal degradation of BMAL1.
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma.
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Baicalein benefits amyotrophic lateral sclerosis via reduction of Intraneuronal misfolded protein.
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane.
hnRNPA2B1 restrains granulosa cell ferroptosis by m(6)A/SLC7A11 in premature ovarian failure.
Paeonol ameliorates diabetic nephropathy by promoting TFEB-mediated lysosome biogenesis and lipophagy.
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Interferon-stimulated gene MCL1 inhibits foot-and-mouth disease virus replication by modulating mitochondrial dynamics and autophagy.
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA.
Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma.
Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death.
Uridine alleviates the aging of alveolar epithelial cells in idiopathic pulmonary fibrosis through the Keap1-Nrf2 signaling pathway.
Kumatakenin alleviates depressive-like behaviors by suppressing excessive autophagy in hippocampus via ATG5.
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Genetic perturbation of cellular homeostasis regulates integrated stress response signaling to control Drosophila hematopoiesis.
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus.
Hydroxychloroquine confers placental protection in antiphospholipid Syndrome: Mechanistic insights into autophagy regulation and trophoblast dysfunction.
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity.
Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO(4) in porcine ovarian granulosa cells.
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.
MYC-dependent MiR-7-5p regulated apoptosis and autophagy in diffuse large B cell lymphoma by targeting AMBRA1.
Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy.
Single-cell analysis combined with transcriptome sequencing identifies autophagy hub genes in macrophages after spinal cord injury.
Deciphering glioblastoma pathogenesis: Insights from mitophagy dysregulation and SNX7 as a therapeutic target.
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes.
Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity.
IL-17A's role in exacerbating radiation-induced lung injury: Autophagy impairment via the PP2A-mTOR pathway.
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
Long-Term Administration of Nicotinamide Mononucleotide Mitigates High-Fat-Diet-Induced Physiological Decline in Aging Mice.
POU4F1 enhances lung cancer gemcitabine resistance by regulating METTL3-dependent TWF1 mRNA N6 adenosine methylation.
Isoliquiritin targeting m5C RNA methylation improves mitophagy in doxorubicin-induced myocardial cardiotoxicity.
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
STIM1 promotes cervical cancer progression through autophagy activation via TFEB nuclear translocation.
The BET inhibitor JQ1 suppresses tumor survival by ABCB5-mediated autophagy in uveal melanoma.
Rapamycin ameliorates inflammatory pain via recovery of autophagy flux mediated by mammalian target of rapamycin (mTOR) signaling pathway in the rat spinal cord.
A patient-specific engineered tissue model of BAG3-mediated cardiomyopathy.
Gboxin Induced Apoptosis and Ferroptosis of Cervical Cancer Cells by Promoting Autophagy-Mediated Inhibition of Nrf2 Signaling Under Low-Glucose Conditions.
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1.
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer.
Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors.
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis.
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
Heat Tolerance-Associated circRNA3685 Regulates Apoptosis and Autophagy in Bovine Mammary Epithelial Cells via Sponging bta-miR-138.
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress.
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice.
Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
CAVIN2 attenuates ventilator-induced lung injury in rats by MAPK/ERK1/2 signaling pathway.
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
LC3B-regulated autophagy mitigates zinc oxide nanoparticle-induced epithelial cell dysfunction and acute lung injury.
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Bradykinin attenuates NiSO(4)-induced autophagy in MIN6 cells and protects islet function in mice by regulating the PI3K/AKT/mTOR signaling pathway.
Dimethyl fumarate alleviate hepatic ischemia-reperfusion injury through suppressing cGAS-STING signaling.
Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson's disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Puerarin Reversing Autophagy-Lysosomal Dysfunction via Acid Sphingomyelinase Inhibition in Cardiomyocytes.
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
Impaired degradation of PLCG1 by chaperone-mediated autophagy promotes cellular senescence and intervertebral disc degeneration.
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
N(6)-Methyladenosine modification mediated by METTL3 promotes DNA-PKcs expression to induce anlotinib resistance in osteosarcoma.
Natural molecule isoliquiritigenin mitigates MASH and liver fibrosis in mice by promoting autophagy through the PI3K/Akt signaling pathway.
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Beclin1 regulates yak endometrial inflammation and TLR4/NF-κB signaling pathway through autophagy/non-autophagy function.
Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Exposure to Nanoplastics During Pregnancy Induces Brown Adipose Tissue Whitening in Male Offspring.
Bone marrow mesenchymal stem cells alleviate neurological dysfunction by reducing autophagy damage via downregulation of SYNPO2 in neonatal hypoxic-ischemic encephalopathy rats.
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer.
RNF167 mediates atypical ubiquitylation and degradation of RLRs via two distinct proteolytic pathways.
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
Paeoniflorin Inhibits Porcine Circovirus Type 2 Replication by Inhibiting Autophagy and Targeting AKT/mTOR Signaling.
Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling.
BLM knockdown promotes cells autophagy via p53-AMPK-mTOR pathway in triple negative breast cancer cells.
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Layered Double Hydroxide LDH-Loaded miR-141-3p Targets RAB10 Suppressing Cellular Autophagy to Reverse Paclitaxel Resistance in Breast Cancer.
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
In situ architecture of the intercellular organelle reservoir between epididymal epithelial cells by volume electron microscopy.
The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance.
Hypoxia Regulates the Proliferation and Apoptosis of Coronary Artery Smooth Muscle Cells Through HIF-1α Mediated Autophagy in Yak.
INHIBITING SIRT2 ATTENUATES SEPSIS-INDUCED ACUTE KIDNEY INJURY VIA FOXO1 ACETYLATION-MEDIATED AUTOPHAGY ACTIVATION.
Aggregatin is a mitochondrial regulator of MAVS activation to drive innate immunity.
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection.
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression.
Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis.
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Integrating superlubricative nanomaterials with precision drug delivery for advanced osteoarthritis therapy.
Biomolecule-tailored chiral nickel oxide nanozymes amplify autophagy-mediated tumor ablation via synergistic photodynamic-chemodynamic therapy.
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Electroacupuncture Improves Pregnancy Outcomes of Assisted Reproduction and Mitochondrial Function of Granulosa Cells in Patients with Polycystic Ovary Syndrome of Phlegm-Dampness Syndrome.
COX-2 targeting Ru-arene complexes from metal-ligand synergistic enhancement strategy for breast cancer therapy.
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
Dysfunctional autophagy triggers STING1 activation to exacerbate cartilage degeneration in obesity-associated osteoarthritis.
Inflammatory signaling attenuates spliceosome function and cognitive ability.
Deacetylation of ATG16L1 is required for LC3-associated lysosomal microautophagy.
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication.
MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma.
Comparative Evaluation of Spores and Vegetative Forms of Bacillus subtilis and Bacillus licheniformis on Probiotic Functionality In Vitro and In Vivo.
Laminar double hydroxide-loaded miR-654-3p targets POU2F1-mediated metabolic reprogramming against colorectal cancer.
Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77.
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Ginsenoside Rb1 alleviates atherosclerosis by modulating vascular smooth muscle cell proliferation, foam cell formation, and autophagy.
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
PARP inhibitors accumulate B7-H3 on fibroblasts via blocking autophagic flux to potentiate immune evasion in ovarian cancer.
Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Inhibitory Effect of Sirtuin6 on EndMT by Regulating Oxidative Stress and Autophagy in Coxsackievirus B3-Induced Cardiac Endothelial Cells.
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16-OPTN Axis in Glioblastoma.
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
FUT3-B3GNT3 interaction promotes pancreatic cancer progression and chemoresistance via NF-κB signaling mediated autophagy.
OPRK1 drives SLC9A3R1 progression to neuroendocrine prostate cancer.
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
A20 Attenuates Inflammatory Injury in Bovine Endometrial Epithelial Cells Through Autophagy-Mediated NLRP3 Inflammasome Inactivation.
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Lysosomal escape and TMEM106B fibrillar core determine TDP-43 seeding outcomes.
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy-lysosomal pathway: an experimental study.
Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus.
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13.
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Hemorrhagic shock and reperfusion induced cognitive impairment through HIF3α/SIRT1.
LC3-dependent intercellular transfer of phosphorylated STAT1/2 elicits CXCL9+ macrophages and enhances radiation-induced antitumor immunity.
Effect of spermidine on cuproptosis in follicular granulosa cells.
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
SDF2L1 downregulation mediates high glucose-caused Schwann cell dysfunction by inhibiting nuclear import of TFEB and CREB via KPNA3.
Zn(2+)-driven metformin conjugated with siRNA attenuates osteoarthritis progression by inhibiting NF-κB signaling and activating autophagy.
H3K36me2 methyltransferase NSD2/WHSC1 promotes triple-negative breast cancer metastasis via activation of ULK1-dependent autophagy.
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
FKBP10 Silencing Alleviates Gluteal Muscle Contracture by Inhibiting Fibrosis and Restoring Autophagy via HSP47/SMAD3 Pathway Inactivation.
TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy.
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8-AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma.
Whey protein hydrolysate alleviated acetaminophen-induced hepatocyte pyroptosis by activating mitophagy.
HSP90 deficiency promotes cholesteryl ester accumulation in lipid droplets via endocytosis of low-density lipoprotein.
DHRS9 promotes malignant progression of ovarian cancer through SQSTM1.
PP2A attenuates α-amanitin-induced liver injury by promoting autophagy and inhibiting apoptosis in mouse models.
Pure platelet-rich plasma delays intervertebral disc degeneration by activating SIRT1-mediated autophagy in nucleus pulposus cells.
Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis.
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
Comprehensive Transcriptomic and m6A Epitranscriptomic Analysis Reveals Colchicine-Induced Kidney Toxicity via DNA Damage and Autophagy in HK2 Cells.
Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation.
Hepatocyte-Enriched miRNA-193b-3p Promotes Hepatitis B Virus Replication by Dual Activation of Viral Core Promoter Activity and Autophagy Induction by Targeting IGF-1R.
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Clomiphene and dexamethasone inhibit apoptosis and autophagy via the ROS-JNK/MAPK-P21 signaling pathway in PCOS.
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.
VDAC1 Inhibition Protects Against Noise-Induced Hearing Loss via the PINK1/Parkin Pathway.
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.
Dietary cinnamon promotes longevity and extends healthspan via mTORC1 and autophagy signaling.
Overexpression of hnRNPK and inhibition of cytoplasmic translocation ameliorate lipid disorder in doxorubicin-induced cardiomyopathy via PINK1/Parkin-mediated mitophagy.
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Novel Parkin agonists from Poria cocos against dyslipidemia.
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
3-D Sustained-Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells.
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Apolipoprotein M delays the development of atherosclerosis by regulating autophagy and mitochondrial function.
Exploring the Molecular Mechanism of 1,25(OH)(2)D(3) Reversal of Sorafenib Resistance in Hepatocellular Carcinoma Based on Network Pharmacology and Experimental Validation.
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
LncRNA HITT inhibits autophagy by attenuating ATG12-ATG5-ATG16L1 complex formation.
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse.
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
3,4-Dimethoxychalcone alleviates limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and antioxidative response.
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein.
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
USP18 Antagonizes Pyroptosis by Facilitating Selective Autophagic Degradation of Gasdermin D.
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Leukemia Inhibitory Factor Protects against Degeneration of Cone Photoreceptors Caused by RPE65 Deficiency.
Method to Purify Phase-Separated p62 Bodies Using Fluorescence-Activated Particle Sorting.
Evidence for the potential role of m6A modification in regulating autophagy in models of amyotrophic lateral sclerosis.
The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels.
The PI3K/Akt-Nrf2 Signaling Pathway and Mitophagy Synergistically Mediate Hydroxytyrosol to Alleviate Intestinal Oxidative Damage.
Zinc Oxide Nanoparticles Exacerbate Epileptic Seizures by Modulating the TLR4-Autophagy Axis.
Overexpression of TRPV1 activates autophagy in human lens epithelial cells under hyperosmotic stress through Ca(2+)-dependent AMPK/mTOR pathway.
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
IRGM Deficiency Exacerbates Sepsis-Induced Acute Lung Injury by Inhibiting Autophagy Through the AKT/mTOR Signaling Pathway.
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
JiangyaTongluo decoction ameliorates tubulointerstitial fibrosis via regulating the SIRT1/PGC-1α/mitophagy axis in hypertensive nephropathy.
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
HSP90B1 regulates autophagy via PI3K/AKT/mTOR signaling, mediating HNSC biological behaviors.
EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy.
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Enhancing Rab7 Activity by Inhibiting TBC1D5 Expression Improves Mitophagy in Alzheimer's Disease Models.
IGF2BP2 modulates autophagy and serves as a prognostic marker in glioma.
ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.
ent-8(14),15-Pimaradiene-2β,19-diol, a diterpene from Aleuritopteris albofusca, inhibits growth and induces protective autophagy in hepatocellular carcinoma cells.
Urolithin A exerts anti-tumor effects on gastric cancer via activating autophagy-Hippo axis and modulating the gut microbiota.
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
The Role of BNIP3 and Blocked Autophagy Flux in Arsenic-Induced Oxidative Stress-Induced Liver Injury in Rats.
FoxO1 silencing in Atp7b(-/-) neural stem cells attenuates high copper-induced apoptosis via regulation of autophagy.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
The role of DNA damage response in human embryonic stem cells exposed to atmospheric oxygen tension: Implications for embryo development and differentiation.
3-Hydroxy-3-methylglutaryl-CoA synthase 2 facilitates erectile dysfunction via inhibiting autophagy by enhancing the mammalian target of rapamycin pathway in type 1 diabetic mellitus rats.
Autophagy Deficiency Induced by SAT1 Potentiates Tumor Progression in Triple-Negative Breast Cancer.
Acteoside delays the fibrosis process of diabetic nephropathy by anti-oxidation and regulating the autophagy-lysosome pathway.
Acid sphingomyelinase inhibition induces cerebral angiogenesis post-ischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism.
LncRNA MIAT suppresses inflammation in LPS-induced J774A.1 macrophages by promoting autophagy through miR-30a-5p/SOCS1 axi.
Isorhapontigenin delays senescence and matrix degradation of nucleus pulposus cells via PI3K/AKT/mTOR-mediated autophagy pathway in vitro and alleviates intervertebral disc degeneration in vivo.
Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.
Autophagy defects at weaning impair complement-dependent synaptic pruning and induce behavior deficits.
Exposure to Succinate Leads to Steatosis in Non-Obese Non-Alcoholic Fatty Liver Disease by Inhibiting AMPK/PPARα/FGF21-Dependent Fatty Acid Oxidation.
Schisandrin B attenuates bleomycin-induced pulmonary fibrosis in mice through AKT-mTOR pathway.
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study.
Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy.
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma.
SS-31 mitigates oxidative stress and restores mitochondrial function in cigarette smoke-damaged oral epithelial cells via PINK1-mediated mitophagy.
Lubricin-Inspired Nanozymes Reconstruct Cartilage Lubrication System with an "In-Out" Strategy.
Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction.
Placental growth factor alleviates hyperglycemia-induced trophoblast pyroptosis by regulating mitophagy.
Electroacupuncture ameliorates senile osteoporosis by promoting bone remodeling and regulating autophagy.
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Sparassis latifolia polysaccharide alleviated lipid metabolism abnormalities in kidney of lead-exposed mice by regulating oxidative stress-mediated inflammation and autophagy based on multi-omics.
Truncation mutations of CRYGD gene in congenital cataracts cause protein aggregation by disrupting the structural stability of γD-crystallin.
RNF144B negatively regulates antiviral immunity by targeting MDA5 for autophagic degradation.
S100A9-TLR4 axis aggravates dry eye through the blockage of autophagy.
PLK2-mediated phosphorylation of SQSTM1 S349 promotes aggregation of polyubiquitinated proteins upon proteasomal dysfunction.
TMX2 potentiates cell viability of hepatocellular carcinoma by promoting autophagy and mitophagy.
Bunyavirus SFTSV NSs utilizes autophagy to escape the antiviral innate immune response.
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS, ER stress, and blocked autophagy.
Blocking ACSL6 Compromises Autophagy via FLI1-Mediated Downregulation of COLs to Radiosensitize Lung Cancer.
The Hemagglutinin of Influenza A Virus Induces Ferroptosis to Facilitate Viral Replication.
A20 Alleviates the Inflammatory Response in Bovine Endometrial Epithelial Cells by Promoting Autophagy.
Overcoming multi-drug resistance in SCLC: a synergistic approach with venetoclax and hydroxychloroquine targeting the lncRNA LYPLAL1-DT/BCL2/BECN1 pathway.
MiR-155-5p regulates autophagy and apoptosis of glioma cells through RICTOR.
Quercetin activates autophagy in the distal ischemic area of random skin flaps through Beclin1 to enhance the adaptability to energy deficiency.
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Potential role of host autophagy in Clonorchis sinensis infection.
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Black phosphorus nanosheets induce autophagy dysfunction by a size- and surface modification-related impairment of lysosomes in macrophages.
Silica nanoparticles cause ovarian dysfunction and fertility decrease in mice via oxidative stress-activated autophagy and apoptosis.
Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer's disease.
Tumor-associated macrophages/C-X-C motif chemokine ligand 1 promotes breast cancer autophagy-mediated chemoresistance via IGF1R/STAT3/HMGB1 signaling.
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
Continuous Theta Burst Stimulation Inhibits Oxidative Stress-Induced Inflammation and Autophagy in Hippocampal Neurons by Activating Glutathione Synthesis Pathway, Improving Cognitive Impairment in Sleep-Deprived Mice.
GL-V9 Promotes Autophagy-Mediated YAP1 Degradation and Activates Mitochondrial Apoptosis in PDAC Cells.
The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.
Hexavalent chromium reduces testosterone levels by impairing lipophagy and disrupting lipid metabolism homeostasis: Based on a metabolomic analysis.
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti-AD compound, screened via network proximity and gene enrichment analyses.
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
High levels of mitochondrial dynamics, autophagy, and apoptosis contribute to stable testicular status in hibernating Daurian ground squirrels.
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
(-)-Epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation.
Angiopoietin 1 Relieves Osteolysis by Promoting Macrophage Mitophagy Through the TBK1-SQSTM1 Pathway to Inhibit AIM2 Inflammasome-Mediated Pyroptosis.
Expediting the development of robust 5-FU-resistant colorectal cancer models using innovative combined in vivo and in vitro strategies.
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer.
Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy.
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity.
Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation.
Trehalose Alleviates D-Galactose-Induced Aging-Related Granulosa Cell Death in Ovaries.
Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy.
Cremastrae Pseudobulbus Pleiones Pseudobulbus (CPPP) Against Non-Small-Cell Lung Cancer: Elucidating Effective Ingredients and Mechanism of Action.
LncRNA AGAP2-AS1 stabilizes ATG9A to promote autophagy in endothelial cells - Implications for burn wound healing.
Soybean isoflavones protect dopaminergic neurons from atrazine damage by inhibiting VPS13A to increase autophagy.
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
USP26 promotes colorectal cancer tumorigenesis by restraining PRKN-mediated mitophagy.
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner.
Tau regulates Arc stability in neuronal dendrites via a proteasome-sensitive but ubiquitin-independent pathway.
Nicotinamide ribose ameliorates myocardial ischemia/reperfusion injury by regulating autophagy and regulating oxidative stress.
NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway.
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
UBC9-mediated SUMOylation of Lamin B1 enhances DNA-damage-induced nuclear DNA leakage and autophagy after spinal cord injury.
Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy.
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes.
Label-Free Three-Dimensional Morphological Characterization of Cell Death Using Holographic Tomography.
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias.
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
AMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy.
Curdepsidone A Induces Intrinsic Apoptosis and Inhibits Protective Autophagy via the ROS/PI3K/AKT Signaling Pathway in HeLa Cells.
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
Selenomethionine preconditioned mesenchymal stem cells derived extracellular vesicles exert enhanced therapeutic efficacy in intervertebral disc degeneration.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Autophagy activity is increased in the cumulus cells of women with poor ovarian response.
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Selective degradation of PL2L60 by metabolic stresses‑induced autophagy suppresses multi‑cancer growth.
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitro.
CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction.
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Kaempferol improves Pb-induced cognitive impairments via inhibiting autophagy.
Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke.
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis.
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Glucosylceramide accumulation in microglia triggers STING-dependent neuroinflammation and neurodegeneration in mice.
Novel TFG mutation causes autosomal-dominant spastic paraplegia and defects in autophagy.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
CircUTRN24/miR-483-3p/IGF-1 Regulates Autophagy Mediated Liver Fibrosis in Biliary Atresia.
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3.
Identification critical host factors for Japanese encephalitis virus replication via CRISPR screening of human sgRNA library.
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.
CYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells.
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Microbial metabolite sodium butyrate enhances the anti-tumor efficacy of 5-fluorouracil against colorectal cancer by modulating PINK1/Parkin signaling and intestinal flora.
Hypoxia-inducible factor prolyl hydroxylase inhibitor alleviates heatstroke-induced acute kidney injury by activating BNIP3-mediated mitophagy.
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS-RAF1-MEK1/2-ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy.
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
Myostatin regulates energy homeostasis through autocrine- and paracrine-mediated microenvironment communication.
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Hsa_circ_0096157 silencing suppresses autophagy and reduces cisplatin resistance in non-small cell lung cancer by weakening the Nrf2/ARE signaling pathway.
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
FUDNC1-dependent mitophagy ameliorate motor neuron death in an amyotrophic lateral sclerosis mouse model.
Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro.
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice.
THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B-CaMKII-ERK1/2 pathway.
The HSP90AA1 gene is involved in heat stress responses and its functional genetic polymorphisms are associated with heat tolerance in Holstein cows.
Neonatal Exposure to Polystyrene Nanoplastics Impairs Microglia-Mediated Synaptic Pruning and Causes Social Behavioral Defects in Adulthood.
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor.
Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response.
Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering.
Defective ferritinophagy and imbalanced iron metabolism in PBDE-47-triggered neuronal ferroptosis and salvage by Canolol.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia‒reperfusion injury.
CDK5-USP30 signaling pathway regulates MAVS-mediated inflammation via suppressing mitophagy in MPTP/MPP(+) PD model.
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
GPSM1 in POMC neurons impairs brown adipose tissue thermogenesis and provokes diet-induced obesity.
Overexpression of SESN1 improves mitochondrial damage and mitophagy, a potential therapeutic strategy for cognitive dysfunction after anaesthesia.
Human filaggrin monomer does not seem to be a proteasome target.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy.
CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in LPS-induced mouse model of depression.
Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
Exosomal microRNA profiling revealed enhanced autophagy suppression and anti-tumor effects of a combination of compound Phyllanthus urinaria and lenvatinib in hepatocellular carcinoma.
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells.
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
Targeting ENPP1 depletion may be a promising therapeutic strategy for treating oral squamous cell carcinoma via cytotoxic autophagy-related apoptosis.
Evidence for Involvement of ADP-Ribosylation Factor 6 in Intracellular Trafficking and Release of Murine Leukemia Virus Gag.
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region.
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
SNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway.
Quercetin stimulates trophoblast fusion via the mitochondrial function.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Interleukin-37 relieves PM2.5-triggered lung injury by inhibiting autophagy through the AKT/mTOR signaling pathway in vivo and in vitro.
Autophagy activation alleviates the LPS-induced inflammatory response in endometrial epithelial cells in dairy cows.
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Reticulon 3 regulates sphingosine-1-phosphate synthesis in endothelial cells to control blood pressure.
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway.
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents.
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Inhibition of SIRT7 promotes STAT1 activation and STAT1-dependent signaling in hepatocellular carcinoma.
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte.
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
BOP1 contributes to the activation of autophagy in polycystic ovary syndrome via nucleolar stress response.
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
PPAR γ activation in chondrocytes alleviates glucocorticoid-induced oxidative stress, mitochondrial impairment, and pyroptosis via autophagic flow enhancement.
Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence.
Gonococcal OMV-delivered PorB induces epithelial cell mitophagy.
M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.
Mitochondria-mediated ferroptosis contributes to the inflammatory responses of bovine viral diarrhea virus (BVDV) in vitro.
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Activation of the p62-Keap1-Nrf2 pathway improves pulmonary arterial hypertension in MCT-induced rats by inhibiting autophagy.
2'-Hydroxychalcone Induces Autophagy and Apoptosis in Breast Cancer Cells via the Inhibition of the NF-κB Signaling Pathway: In Vitro and In Vivo Studies.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy.
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1.
ATF4/PHGDH mediates the effects of ER stress on cadmium-induced autophagy and glycolysis.
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Association between mitophagy and NLRP3 inflammasome in uric acid nephropathy.
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins.
Degarelix limits the survival of mycobacteria and granuloma formation.
The RIP3 activator C8 regulates the autophagy flux mediated by p62 and promotes the immunogenic form of cell death in human gastric cancer cells.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.
Lipopolysaccharide-regulated RNF31/NRF2 axis in colonic epithelial cells mediates homeostasis of the intestinal barrier in ulcerative colitis.
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions.
Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity.
Fisetin Ameliorates Hepatocyte Lipid Droplet Accumulation via Targeting the Rhythmic Protein BMAL1 to Regulate Cell Death-Inducing DNA Fragmentation Factor-α-like Effector C-Mediated Lipid Droplet Fusion.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Stilbene glycosides alleviate atherosclerosis partly by promoting lipophagy of dendritic cells.
mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin.
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Redox homeostasis of one-carbon metabolism-dependent reprogramming is critical for RCC progression under exogenous serine/glycine-deprived conditions.
LOC730101 improves ovarian cancer drug sensitivity by inhibiting autophagy-mediated DNA damage repair via BECN1.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
DEHP regulates ferritinophagy to promote testicular ferroptosis via suppressing SIRT1/PGC-1α pathway.
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes.
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Curcumin inhibits PAT-induced renal ferroptosis via the p62/Keap1/Nrf2 signalling pathway.
EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis.
Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway.
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway.
Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats.
Novel meroterpene-like compounds inhibit ferroptosis through Fe(2+) chelation.
L-Alanine promotes anti-infectious properties of Bacillus subtilis S-2 spores via the germination receptor gerAA.
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
Melatonin alleviates palmitic acid-induced mitochondrial dysfunction by reducing oxidative stress and enhancing autophagy in bovine endometrial epithelial cells.
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
Identification and Validation of the miR/RAS/RUNX2 Autophagy Regulatory Network in AngII-Induced Hypertensive Nephropathy in MPC5 Cells Treated with Hydrogen Sulfide Donors.
NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling.
RILP Induces Cholesterol Accumulation in Lysosomes by Inhibiting Endoplasmic Reticulum-Endolysosome Interactions.
Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Cajaninstilbene acid ameliorates depression-like behaviors in mice by suppressing TLR4/NF-κB mediated neuroinflammation and promoting autophagy.
Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis.
Regulatory role of the mTOR signaling pathway in autophagy and mesangial proliferation in IgA nephropathy.
Mitochondria-Targeted Multifunctional Nanoprodrugs by Inhibiting Metabolic Reprogramming for Combating Cisplatin-Resistant Lung Cancer.
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress.
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
MiR-181a-5p may regulate cell proliferation and autophagy in myopia and the associated retinopathy.
CIRBP Increases the synthesis and secretion of steroid hormones by in yak granulaso cells.
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Selenomethionine Inhibits NF-κB-mediated Inflammatory Responses of Bovine Mammary Epithelial Cells Caused by Klebsiella pneumoniae by Increasing Autophagic Flux.
DDIT3/CHOP promotes LPS/ATP-induced pyroptosis in osteoblasts via mitophagy inhibition.
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
TFEB regulates the odontoblastic differentiation of dental pulp stem cells by promoting a positive feedback loop between mitophagy and glycolysis.
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
Effect of beta-cypermethrin on the reproductive capacity of female mice in advanced age.
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
HACD3 Prevents PB1 from Autophagic Degradation to Facilitate the Replication of Influenza A Virus.
RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation.
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Protective effects of pulsed electromagnetic field therapy attenuates autophagy and apoptosis in osteoporotic osteoarthritis model rats by activating PPARγ.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Triamcinolone acetonide induces the autophagy of Ag85B-treated WI-38 cells via SIRT1/FOXO3 pathway.
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.
Deciphering the Molecular Mechanism of Yifei-Sanjie Pill in Cancer-Related Fatigue.
Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
TNFR2 deficiency impairs the growth of mouse colon cancer.
Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration.
Construction and validation of a prognostic signature based on necroptosis-related genes in hepatocellular carcinoma.
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway.
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
C. tropicalis promotes CRC by down-regulating tumor cell-intrinsic PD-1 receptor via autophagy.
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Echovirus induces autophagy to promote viral replication via regulating mTOR/ULK1 signaling pathway.
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma.
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
SIRT6 drives sensitivity to ferroptosis in anaplastic thyroid cancer through NCOA4-dependent autophagy.
The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence.
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Baicalin promotes random-pattern skin flap survival by inducing autophagy via AMPK-regulated TFEB nuclear transcription.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity.
CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Apatinib combined with olaparib induces ferroptosis via a p53-dependent manner in ovarian cancer.
Liensinine pretreatment reduces inflammation, oxidative stress, apoptosis, and autophagy to alleviate sepsis acute kidney injury.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Spermidine alleviating oxidative stress and apoptosis by inducing autophagy of granulosa cells in Sichuan white geese.
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Cancer/testis antigen CAGE mediates osimertinib resistance in non-small cell lung cancer cells and predicts poor prognosis in patients with pulmonary adenocarcinoma.
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover.
Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers.
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation.
Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
The adhesion G protein-coupled receptor VLGR1/ADGRV1 controls autophagy.
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells.
Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling.
TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.
Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration.
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin-Angiotensin System in Mice.
Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction.
Visual impairment cell non-autonomously dysregulates brain-wide proteostasis.
Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease.
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Cadmium induces apoptosis of mouse spermatocytes through JNK activation and disruption of autophagic flux.
Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia.
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Role of SIRT2 in intestinal barrier under cold exposure.
Differential regulation of autophagy on urine-concentrating capability through modulating the renal AQP2 expression and renin-angiotensin system in mice.
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages.
Plasma metabonomic study on the effect of Para‑hydroxybenzaldehyde intervention in a rat model of transient focal cerebral ischemia.
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage.
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Activation of Nrf2/ARE pathway by Anisodamine (654-2) for Inhibition of cellular aging and alleviation of Radiation-Induced lung injury.
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Six-hour time-restricted feeding inhibits lung cancer progression and reshapes circadian metabolism.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival.
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells.
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice.
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Modulation of virus-induced neuroinflammation by the autophagy receptor SHISA9 in mice.
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats.
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression.
Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis.
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR.
P‑hydroxybenzyl alcohol ameliorates neuronal cerebral ischemia‑reperfusion injury by activating mitochondrial autophagy through SIRT1.
MiR-141-3p promotes hypoxia-induced autophagy in human placental trophoblast cells.
Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
Aqueous extract of Sanghuangporus baumii induces autophagy to inhibit cervical carcinoma growth.
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ERα degradation and the autophagy-lysosome pathway.
YTHDF2 controls hexavalent chromium-induced mitophagy through modulating Hif1α and Bnip3 decay via the m(6)A/mRNA pathway in spermatogonial stem cells/progenitors.
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Pre-ischaemic Treatment with Enriched Environment Alleviates Acute Neuronal Injury by Inhibiting Endoplasmic Reticulum Stress-dependent Autophagy and Apoptosis.
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
YAP1 suppression inhibits autophagy and improves the efficacy of anti-PD-1 immunotherapy in hepatocellular carcinoma.
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Ursolic acid nanoparticles for glioblastoma therapy.
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure.
CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP-43 and Encoding A Novel TMEFF1-339aa Protein.
Mitochondrial damage-induced abnormal glucose metabolism with ageing in the hippocampus of APP/PS1 mice.
RETRACTED: Tangzhiqing-mediated NRF2 reduces autophagy-dependent ferroptosis to mitigate diabetes-related cognitive impairment neuronal damage.
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
miR-210 promotes hepatocellular carcinoma progression by modulating macrophage autophagy through PI3K/AKT/mTOR signaling.
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway.
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.
Impairment of autophagy promotes human conjunctival fibrosis and pterygium occurrence via enhancing the SQSTM1-NF-κB signaling pathway.
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Homoplantaginin attenuates high glucose-induced vascular endothelial cell apoptosis through promoting autophagy via the AMPK/TFEB pathway.
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
Proteomics of Plasma and Plasma-Treated Podocytes: Application to Focal and Segmental Glomerulosclerosis.
Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells.
ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway.
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe(3)O(4) in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway.
Cold exposure protects against medial arterial calcification development via autophagy.
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex.
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner.
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
SIRT3 attenuates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome via autophagy.
Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia.
Berberine enhances autophagic flux by activating the Nrf2 signaling pathway in bovine endometrial epithelial cells to resist LPS-induced apoptosis.
Ischemic Stroke Induces Skeletal Muscle Damage and Alters Transcriptome Profile in Rats.
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4.
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis.
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis.
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Effects of exogenous spermidine on autophagy and antioxidant capacity in ovaries and granulosa cells of Sichuan white geese.
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis.
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Design, synthesis and anti-ovarian cancer activities of thieno[2,3-d]pyrimidine based chimeric BRD4 inhibitor/nitric oxide-donator.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers.
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Targeting Annexin A1 as a Druggable Player to Enhance the Anti-Tumor Role of Honokiol in Colon Cancer through Autophagic Pathway.
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
N(6)-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Combination of a New Oral Demethylating Agent, OR2100, and Venetoclax for Treatment of Acute Myeloid Leukemia.
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
Apilimod enhances specific productivity in recombinant CHO cells through cell cycle arrest and mediation of autophagy.
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKβ-AMPK-mTOR-mediated autophagy.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.
Ame-miR-980-3p participates in autophagy-mediated midgut remodelling in Apis mellifera via targeting Atg2B.
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway.
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
FUNDC1/PFKP-mediated mitophagy induced by KD025 ameliorates cartilage degeneration in osteoarthritis.
SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1.
Imidacloprid Induces Lysosomal Dysfunction and Cell Death in Human Astrocytes and Fibroblasts-Environmental Implication of a Clinical Case Report.
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Cataract-causing mutations S78F and S78P of γD-crystallin decrease protein conformational stability and drive aggregation.
Tetrahydropalmatine: Orchestrating survival - Regulating autophagy and apoptosis via the PI3K/AKT/mTOR pathway in perforator flaps.
GNL3L promotes autophagy via regulating AMPK signaling in esophageal cancer cells.
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Data-independent acquisition (DIA) mass spectrometry reveals related proteins involved in the occurrence of early intestinal-type gastric cancer.
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects.
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Blockade of CXCR4 promotes macrophage autophagy through the PI3K/AKT/mTOR pathway to alleviate coronary heart disease.
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
Artemether ameliorates adriamycin induced cardiac atrophy in mice.
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.
Arginine regulates HSPA5/BiP translation through ribosome pausing in triple-negative breast cancer cells.
Experimental Study of Warburg Effect in Keloid Nodules: Implication for Downregulation of miR-133b.
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
The Chicken cGAS-STING Pathway Exerts Interferon-Independent Antiviral Function via Cell Apoptosis.
TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines.
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Metabolomic Analysis of Trehalose Alleviating Oxidative Stress in Myoblasts.
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia.
Adipose-derived mesenchymal stem cell therapy for reverse bleomycin-induced experimental pulmonary fibrosis.
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Dysregulation of lipid metabolism in the pseudolobule promotes region-specific autophagy in hepatitis B liver cirrhosis.
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway.
Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells.
Mitochondria-associated endoplasmic reticulum membranes dysfunction contributes to PARP-1-dependent cell death under oxidative stress in retinal precursor cells.
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance.
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway.
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
ATG2B upregulated in LPS-stimulated BMSCs-derived exosomes attenuates septic liver injury by inhibiting macrophage STING signaling.
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Pathogenic mechanism of Eimeria tenella autophagy activation of chicken embryo cecal epithelial cells induced by Eimeria tenella.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux.
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.
The SFTSV Nonstructural Proteins Induce Autophagy to Promote Viral Replication via Interaction with Vimentin.
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
MicroRNA-196-5p targets Derlin-1 to induce autophagy in human osteosarcoma cells.
STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy.
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells.
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.
SUMO1 Promotes Mesangial Cell Proliferation Through Inhibiting Autophagy in a Cell Model of IgA Nephropathy.
The KLF4-p62 axis prevents vascular endothelial cell injury via the mTOR/S6K pathway and autophagy in diabetic kidney disease.
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
BRD4 Inhibition Suppresses Senescence and Apoptosis of Nucleus Pulposus Cells by Inducing Autophagy during Intervertebral Disc Degeneration: An In Vitro and In Vivo Study.
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells.
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
SIRT2 Affects Cell Proliferation and Apoptosis by Suppressing the Level of Autophagy in Renal Podocytes.
Discovery of Therapeutic Candidates for Diabetic Retinopathy Based on Molecular Switch Analysis: Application of a Systematic Process.
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux.
Mesangial Cell-Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2.
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Shikonin Attenuates Cochlear Spiral Ganglion Neuron Degeneration by Activating Nrf2-ARE Signaling Pathway.
Beclin1 Deficiency Suppresses Epileptic Seizures.
The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway.
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection.
Liuwei Dihuang Pills Inhibit Podocyte Injury and Alleviate IgA Nephropathy by Directly Altering Mesangial Cell-Derived Exosome Function and Secretion.
Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy.
Intracellular Ca(2+) Signaling and Calcium Release-Activated Calcium Modulator ORAI1 Are Associated With CD4(+) T Lymphocytes in Dairy Cows.
Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.
Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control.
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Hydrogen sulfide alleviates uremic cardiomyopathy by regulating PI3K/PKB/mTOR-mediated overactive autophagy in 5/6 nephrectomy mice.
Characterization and subcellular localization of Alongshan virus proteins.
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Autophagy-Related Signatures as Prognostic Indicators for Hepatocellular Carcinoma.
PIN1 protects auditory hair cells from senescence via autophagy.
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway.
Gold nanoparticles targeting the autophagy-lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy.
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.
Ferulic acid ameliorates renal injury via improving autophagy to inhibit inflammation in diabetic nephropathy mice.
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Sodium butyrate attenuates bovine mammary epithelial cell injury by inhibiting the formation of neutrophil extracellular traps.
Selenomethionine alleviates NF-κB-mediated inflammation in bovine mammary epithelial cells induced by Escherichia coli by enhancing autophagy.
Lactobacillusjohnsonii L531 Protects against Salmonella Infantis-Induced Intestinal Damage by Regulating the NOD Activation, Endoplasmic Reticulum Stress, and Autophagy.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Puerarin prevents calcium oxalate crystal-induced renal epithelial cell autophagy by activating the SIRT1-mediated signaling pathway.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity.
Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway.
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Combination of an autophagy inhibitor with immunoadjuvants and an anti-PD-L1 antibody in multifunctional nanoparticles for enhanced breast cancer immunotherapy.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
DDX17 promotes the growth and metastasis of lung adenocarcinoma.
Down-regulation of EVA1A by miR-103a-3p promotes hepatocellular carcinoma cells proliferation and migration.
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus.
Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue.
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Subsarcolemmal and cytoplasmic p62 positivity and rimmed vacuoles are distinctive for PLIN4-myopathy.
Palmatine attenuates hepatocyte injury by promoting autophagy via the AMPK/mTOR pathway after alcoholic liver disease.
Impaired autophagy and mitochondrial dynamics are involved in Sorafenib-induced cardiomyocyte apoptosis.
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Curcumin attenuates Cr (VI)-induced cell growth and migration by targeting autophagy-dependent reprogrammed metabolism.
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity.
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Paeoniflorin binds to VEGFR2 to restore autophagy and inhibit apoptosis for podocyte protection in diabetic kidney disease through PI3K-AKT signaling pathway.
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
The Clinicopathological Distinction between Immune-Mediated Necrotizing Myopathy and Limb-Girdle Muscular Dystrophy R2: Key Points to Prevent Misdiagnosis.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel.
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias.
EGFR mediated the renal cell apoptosis in rhabdomyolysis-induced model via upregulation of autophagy.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models.
Ghrelin ameliorates diabetes-associated behavioral deficits and NLRP3 inflammasome activation via autophagic flux enhancement.
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
A transcriptomics and molecular biology based investigation reveals the protective effect and mechanism of carnosol on t-BHP induced HRMECs via Nrf2 signaling pathway.
SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism.
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation.
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.
Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer's disease.
CN-3 increases TMZ sensitivity and induces ROS-dependent apoptosis and autophagy in TMZ-resistance glioblastoma.
Vitamin D3 promotes autophagy in THP-1 cells infected with Mycobacterium tuberculosis.
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Deacetylation of ZKSCAN3 by SIRT1 induces autophagy and protects SN4741 cells against MPP(+)-induced oxidative stress.
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
c-MYC-mediated TRIB3/P62(+) aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2.
Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
Involvement of NEAT1/PINK1-mediated mitophagy in chronic obstructive pulmonary disease induced by cigarette smoke or PM(2.5).
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer.
Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma.
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
The regulation of autophagy by the miR-199a-5p/p62 axis was a potential mechanism of small cell lung cancer cisplatin resistance.
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Acetaldehyde Induces Cytotoxicity via Triggering Mitochondrial Dysfunction and Overactive Mitophagy.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
The role of NOTCH2NLC in Parkinson's disease: A clinical, neuroimaging, and pathological study.
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Autophagy deficiency activates rDNA transcription.
m(6)A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.
Isogenic GAA-KO Murine Muscle Cell Lines Mimicking Severe Pompe Mutations as Preclinical Models for the Screening of Potential Gene Therapy Strategies.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Attenuation of histone H4 lysine 16 acetylation (H4K16ac) elicits a neuroprotection against ischemic stroke by alleviating the autophagic/lysosomal dysfunction in neurons at the penumbra.
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Abnormal accumulation of OFD1 in endometrial cancer with poor prognosis inhibits ciliogenesis.
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Multifunctional theranostic nanoplatform loaded with autophagy inhibitor for enhanced photothermal cancer therapy under mild near-infrared irradiation.
sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death.
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Aggregation-Induced Emission Photosensitizer Synergizes Photodynamic Therapy and the Inhibition of the NF-κB Signaling Pathway to Overcome Hypoxia in Breast Cancer.
Punicalagin Protects against Diabetic Liver Injury by Upregulating Mitophagy and Antioxidant Enzyme Activities.
The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis.
Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway.
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense.
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
Mitochondrial dysfunction is involved in the cellular activity inhibition by eleutheroside B in SMMC-7721 and HeLa cells.
PM2.5 activated NLRP3 inflammasome and IL-1β release in MH-S cells by facilitating autophagy via activating Wnt5a.
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Feeder-supported in vitro exercise model using human satellite cells from patients with sporadic inclusion body myositis.
Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice.
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Biotinylated curcumin as a novel chemosensitizer enhances naphthalimide-induced autophagic cell death in breast cancer cells.
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner.
Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver.
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Improving Lipophagy by Restoring Rab7 Cycle: Protective Effects of Quercetin on Ethanol-Induced Liver Steatosis.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas.
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
RIPK1-RIPK3 mediates myocardial fibrosis in type 2 diabetes mellitus by impairing autophagic flux of cardiac fibroblasts.
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes.
The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy.
The SPATA2/CYLD pathway contributes to doxorubicin-induced cardiomyocyte ferroptosis via enhancing ferritinophagy.
Lactoferrin alleviates spermatogenesis dysfunction caused by bisphenol A and cadmium via ameliorating disordered autophagy, apoptosis and oxidative stress.
Phosphorylated alpha-synuclein in Iba1-positive macrophages in the skin of patients with Parkinson's disease.
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Inhibition of autophagy by 3-methyladenine promotes migration and invasion of colon cancer cells through epithelial mesenchymal transformation.
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.
Stellettin B-Induced Oral Cancer Cell Death via Endoplasmic Reticulum Stress-Mitochondrial Apoptotic and Autophagic Signaling Pathway.
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
Sesamin Ameliorates Fine Particulate Matter (PM(2.5))-Induced Lung Injury via Suppression of Apoptosis and Autophagy in Rats.
ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function.
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer.
PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway.
S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia.
Interpreting the Pharmacological Mechanisms of Sho-saiko-to on Thyroid Carcinoma through Combining Network Pharmacology and Experimental Evaluation.
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy.
Long noncoding RNA ZFP36L2-AS functions as a metabolic modulator to regulate muscle development.
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer's Disease by Network Pharmacology and Experimental Validation.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma.
HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats.
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
IFI30 expression predicts patient prognosis in breast cancer and dictates breast cancer cells proliferation via regulating autophagy.
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway.
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Lactobacillus rhamnosus GR-1 Prevents Escherichia coli-Induced Apoptosis Through PINK1/Parkin-Mediated Mitophagy in Bovine Mastitis.
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in China.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway.
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway.
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model.
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Chronic Restraint Stress-Induced Muscle Atrophy Leads to Fatigue in Mice by Inhibiting the AMPK Signaling Pathway.
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease.
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Fasting improves tolerance to acute hypoxia in rats.
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
l-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Bergenin attenuates bleomycin-induced pulmonary fibrosis in mice via inhibiting TGF-β1 signaling pathway.
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy.
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Co-modification with MSC membrane and PDA prevents Fe(3)O(4)-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.
eIF2A-knockout mice reveal decreased life span and metabolic syndrome.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
Acetylation of STX17 (syntaxin 17) controls autophagosome maturation.
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Interfering with hyaluronic acid metabolism suppresses glioma cell proliferation by regulating autophagy.
Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Lactobacillus salivarius ameliorated Mycoplasma gallisepticum-induced inflammatory injury and secondary Escherichia coli infection in chickens: Involvement of intestinal microbiota.
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts.
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Hongjingtian injection protects against myocardial ischemia reperfusion-induced apoptosis by blocking ROS induced autophagic- flux.
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b.
Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions.
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice.
Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Autophagy inhibition and microRNA‑199a‑5p upregulation in paclitaxel‑resistant A549/T lung cancer cells.
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
The Difference in Expression of Autophagy-Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo-A Cross-Sectional Pilot Study.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Activated autophagy restored the impaired frequency and function of regulatory T cells in chronic prostatitis.
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury.
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Srag Regulates Autophagy via Integrating into a Preexisting Autophagy Pathway in Testis.
Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Atmospheric PM(2.5) blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome.
Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells.
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
ZFP91 is required for the maintenance of regulatory T cell homeostasis and function.
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
The abrupt pathological deterioration of cisplatin-induced acute kidney injury: Emerging of a critical time point.
Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs).
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G(1)/S cycle.
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells.
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis.
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pulmonary Exposure to Copper Oxide Nanoparticles Leads to Neurotoxicity via Oxidative Damage and Mitochondrial Dysfunction.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes.
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
UBXN7 cofactor of CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins.
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
LC3B/p62-mediated mitophagy protects A549 cells from resveratrol-induced apoptosis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis.
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial-Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production.
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Yi-Zhi-Fang-Dai Formula Exerts a Protective Effect on the Injury of Tight Junction Scaffold Proteins in Vitro and in Vivo by Mediating Autophagy through Regulation of the RAGE/CaMKKβ/AMPK/mTOR Pathway.
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
RAB37 multiple alleles, transcription activation and evolution in mammals.
IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.
Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux.
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
The Effect of Autophagy on Chronic Intermittent Hypobaric Hypoxia Ameliorating Liver Damage in Metabolic Syndrome Rats.
NLRC5 Inhibits Inflammation of Secretory Phase Ectopic Endometrial Stromal Cells by Up-Regulating Autophagy in Ovarian Endometriosis.
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
PIWI-Interacting RNA-004800 Is Regulated by S1P Receptor Signaling Pathway to Keep Myeloma Cell Survival.
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo.
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Inhibition of Endoplasmic Reticulum Stress-Mediated Autophagy Enhances the Anticancer Effect of Iodine-125 Seed Radiation on Esophageal Squamous Cell Carcinoma.
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
Phosphorylation of PRAS40 contributes to the activation of the PI3K/AKT/mTOR signaling pathway and the inhibition of autophagy following status epilepticus in rats.
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
[IL-17A/lL-17RA reduces cisplatin sensitivity of ovarian cancer SKOV3 cells by regulating autophagy].
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway.
NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway.
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy.
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Autophagic-CTSB-inflammasome axis modulates hepatic stellate cells activation in arsenic-induced liver fibrosis.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Siderophores induce mitophagy-dependent apoptosis in platelets.
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy.
Dehydroandrographolide inhibits mastitis by activating autophagy without affecting intestinal flora.
Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
A robust TDP-43 knock-in mouse model of ALS.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.
Nobiletin Triggers Reactive Oxygen Species-Mediated Pyroptosis through Regulating Autophagy in Ovarian Cancer Cells.
Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine.
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34.
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Identification of curcumin as a novel natural inhibitor of rDNA transcription.
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis.
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
NAD(+) administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Artemisinin Attenuated Atherosclerosis in High-Fat Diet-Fed ApoE-/- Mice by Promoting Macrophage Autophagy Through the AMPK/mTOR/ULK1 Pathway.
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases.
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
The up-regulation of P62 levels is associated with resistance of sorafenib in hepatocarcinoma cells.
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress.
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate ameliorates pressure overload-induced cardiac hypertrophy and dysfunction through inhibiting autophagy.
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Krüppel‑like factor 4 ameliorates diabetic kidney disease by activating autophagy via the mTOR pathway.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Mitophagy protects against statin-mediated skeletal muscle toxicity.
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Dihydroartemisinin, an antimalarial drug, induces absent in melanoma 2 inflammasome activation and autophagy in human hepatocellular carcinoma HepG2215 cells.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Carfilzomib enhances cisplatin-induced apoptosis in SK-N-BE(2)-M17 human neuroblastoma cells.
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte.
LncRNA ENST00000453774.1 contributes to oxidative stress defense dependent on autophagy mediation to reduce extracellular matrix and alleviate renal fibrosis.
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
ERβ promotes Aβ degradation via the modulation of autophagy.
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Alterations of autophagy in knee cartilage by treatment with treadmill exercise in a rat osteoarthritis model.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Autophagy protects against redox-active trace metal-induced cell death in rabbit synovial fibroblasts through Toll-like receptor 4 activation.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Taurine protected As(2)O(3)-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells.
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Loss of HMBOX1 promotes LPS-induced apoptosis and inhibits LPS-induced autophagy of vascular endothelial cells in mouse.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
FAM134B improves preadipocytes differentiation by enhancing mitophagy.
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway.
Solanesol derived therapeutic carriers for anticancer drug delivery.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Zearalenone induces NLRP3-dependent pyroptosis via activation of NF-κB modulated by autophagy in INS-1 cells.
Quercetin shows anti-tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway.
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function.
Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice.
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease.
Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy.
Silver nanoparticles induce protective autophagy via Ca(2+)/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
Activation of Cyclooxygenase-2 by ATF4 During Endoplasmic Reticulum Stress Regulates Kidney Podocyte Autophagy Induced by Lupus Nephritis.
3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation.
Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway.
Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H(2)S formation.
NLRC5 and autophagy combined as possible predictors in patients with endometriosis.
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Mutant UBQLN2(P497H) in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.
Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells.
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33.
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
Prodigiosin stimulates endoplasmic reticulum stress and induces autophagic cell death in glioblastoma cells.
A tumor-activatable particle with antimetastatic potential in breast cancer via inhibiting the autophagy-dependent disassembly of focal adhesion.
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Potentiating bacterial cancer therapy using hydroxychloroquine liposomes.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress.
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice.
Chronic intermittent hypobaric hypoxia protects vascular endothelium by ameliorating autophagy in metabolic syndrome rats.
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Pancreatic islet-autonomous effect of arsenic on insulin secretion through endoplasmic reticulum stress-autophagy pathway.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Autophagy dysregulation caused by ApoM deficiency plays an important role in liver lipid metabolic disorder.
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.
Pre-treatment with angiotensin-(1-7) inhibits tumor growth via autophagy by downregulating PI3K/Akt/mTOR signaling in human nasopharyngeal carcinoma xenografts.
Autophagy participates in innate immune defense in lamprey.
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats.
Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling.
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Attenuating Spinal Cord Injury by Conditioned Medium from Bone Marrow Mesenchymal Stem Cells.
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
(-)-Guaiol regulates autophagic cell death depending on mTOR signaling in NSCLC.
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease.
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
HMGA2 plays an important role in Cr (VI)-induced autophagy.
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells.
An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis.
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Prion-like transmission of α-synuclein pathology in the context of an NFL null background.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Synergism and mechanism of Astragaloside IV combined with Ginsenoside Rg1 against autophagic injury of PC12 cells induced by oxygen glucose deprivation/reoxygenation.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.
miR-29b contributes to multiple types of muscle atrophy.
BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.
Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway.
The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells.
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1-independent autophagy in mice.
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.
Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1.
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Regulation of Autophagy-Related Protein and Cell Differentiation by High Mobility Group Box 1 Protein in Adipocytes.
Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment.
Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages.
Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition.
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cells.
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
β-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1-dependent autophagy.
Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus.
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Autophagy protects renal tubular cells against ischemia / reperfusion injury in a time-dependent manner.
Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice.
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells.
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux.
Induction of autophagy improves embryo viability in cloned mouse embryos.
Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach.
Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease.
SQSTM1 splice site mutation in distal myopathy with rimmed vacuoles.
Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG(2) cells to epirubicin.
Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis.
Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma.
Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.
mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.
Increased autophagy accelerates colchicine-induced muscle toxicity.
Xue Y, Wan B, Wang Z, Wang Z, Wang D, Yang W, Wang X, Zhu L
Current neuropharmacology 2026;24(3):404-418
Current neuropharmacology 2026;24(3):404-418
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination.
Guo X, Lin Y, Jiang Y, Wang M, Li Y, Gao Y, Chen B, Bao Z, Tian H, Chu X, Zhang Z, Shao J, Zhang F, Wang H, Xuan J, Xu X, Zheng S
International journal of biological sciences 2026;22(3):1648-1673
International journal of biological sciences 2026;22(3):1648-1673
Circular RNA circPLXNC1 functions as an inhibitor of senescence by regulating autophagy in osteoarthritis.
Zhou H, Ji Z, Sun H, Zhang W, Huang Y, Jin G, Cai H, Huang X, Dai J, Zhao J, Chen H, Fan S, Wu Y, Shen J
International journal of biological sciences 2026;22(1):346-364
International journal of biological sciences 2026;22(1):346-364
SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy.
Jiang M, Li J, Ding N, Jia G, Wu S, Liu N, Kang Y, Zhang G, Wu J, Zhang L, Zhang Y
International journal of biological sciences 2026;22(1):178-200
International journal of biological sciences 2026;22(1):178-200
Aspergillus fumigatus Gliotoxin Inhibits LC3-Associated Phagocytosis in Macrophages in a Calcium-Dependent Manner.
Sun Y, Chen F, Zhang L, Zheng C, Wang Y, Zhang Y, Han L
Journal of immunology research 2026;2026(1):e5542735
Journal of immunology research 2026;2026(1):e5542735
Exosomal lncRNA FENDRR Orchestrates Immune Remodelling and Ferroptosis in the Comorbidity of Lung Cancer and Type 1 Myocardial Infarction.
He Y, Qian Y, Zheng Z, Zhou Y, Li C, Wu Q, Ren M
Human mutation 2026;2026:8861747
Human mutation 2026;2026:8861747
C9orf72-ALS mutation drives basal mitophagy impairments in iNeurons.
Lee JAK, Moutin C, Granger S, Roome K, Shaw A, Allen SP, Ferraiuolo L, Shaw PJ, Mortiboys H
Frontiers in cellular neuroscience 2026;20:1731669
Frontiers in cellular neuroscience 2026;20:1731669
Ginsenoside Rg3 Mitigates LPS-Induced Injury in Human Bronchial Epithelial Cells by Restoring Autophagic Flux and Inhibiting the TLR4/NF-κB-Mediated Inflammatory Response.
Tao X, Liu L, Gu X, Jia B, Yu Q, Wei Y, Zhang W, Zhou J
Journal of inflammation research 2026;19:555053
Journal of inflammation research 2026;19:555053
Bitter gourd peptides (BG) alleviate lupus progression in mice through regulation of miR-146a/BRD4 axis in macrophages.
Wu Y, Han W, Li X, Su X
Frontiers in immunology 2026;17:1666212
Frontiers in immunology 2026;17:1666212
Nanosized silicon nitride promotes vascularized osteogenesis through regulating the endothelial adherens junctions via the FRMD6/VE-cadherin pathway.
Wang R, Liu Z, Liu W, Zheng X, Zhao Y, Huang F, Wen S, Gan Y, Huang Z, Zhang Y, Lu Y, Rong M
Biomaterials 2026 Sep;332:124150
Biomaterials 2026 Sep;332:124150
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Li Z, Ma Z, Chen Y, Yu W, Yu J, Lu J, Zhang Q, Wu Q, Cai Y, Wang Z, Shang C, Hou B, Zhang C, Huang S, Wang L, Zhou Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
RNA-binding motif protein 15 promotes gastric cancer growth and drug resistance via USP10-mediated deubiquitination and stabilization of nuclear NRF2.
Ma Z, Xu Z, Xu J, Chen C, Niu W, Wang Y, Qian Y, Zhang X, Yang M, Stefan SM, Gan L, Wang S, Wang B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101376
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101376
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
Zhu T, Jiao X, Shi J, Wang B, Li C, Li Y
Veterinary microbiology 2026 May;316:110993
Veterinary microbiology 2026 May;316:110993
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Li S, Chen L, Fang Z, Shen W, Cai J, Dong B, Lin T, Zhang R, Jin L, Liu C, Wu F, Wu Q, Chen D
Free radical biology & medicine 2026 May;248:401-412
Free radical biology & medicine 2026 May;248:401-412
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
Cheng S, Shi S, Cheng B, Liu C, Yang X, Liu L, Liu H, Wen Y, Tinkov AA, Skalny AV, Jia Y, Zhang F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
vtRNA1-1/p62 regulates macrophages autophagy in ankylosing spondylitis.
Jiang M, Ni J, Yu X, Zhao H, Lu X, Cheng L, Li Z, Wu H, Pan Z, Qu L, Gao M, Cai G, Wang M, Pan F
Molecular immunology 2026 May;193:1-9
Molecular immunology 2026 May;193:1-9
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Ginsenoside Rg1 mitigates sepsis-associated acute respiratory distress syndrome by promoting autophagy through the Prdx1-PTEN/PI3K/AKT pathway.
Xue X, Huang C, Chen J, Ding W, Ren Y, Zhang W, Li Q, Yang Z, Sun Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158027
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158027
Ixazomib triggers autophagic degradation of MUC5AC/integrin-β4 and inhibits non-small cell lung cancer progression.
Appadurai MI, Alsafwani ZW, Chaudhary S, Shah A, Somavarapu P, Dooshety SN, Kubicek BS, Batra SK, Lakshmanan I, Ganti AK
Cancer letters 2026 May 1;645:218333
Cancer letters 2026 May 1;645:218333
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Zhao W, Gong Z, Wang B, Wu Z, Guo Y, Wang S, Zhai H, Zheng X, Yang L
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism.
Li P, Liao R, Li J, Chen S, Diao W, Shi K, Zuo C, Tan S, Li J, Jiang Z, Hu Y, Wu W, Zhou J
Journal of advanced research 2026 Mar;81:781-796
Journal of advanced research 2026 Mar;81:781-796
Ajugoside Promotes the Repair of Osteoporotic Bone by Inducing Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells.
Yang R, Wang C, Xie P, Ye J, Huang S
Clinical and experimental pharmacology & physiology 2026 Mar;53(3):e70114
Clinical and experimental pharmacology & physiology 2026 Mar;53(3):e70114
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Ma X, Lei P, Ren B, Xie S, Zhang Y, Wang Y, Ma W
Archives of pharmacal research 2026 Mar;49(3):357-374
Archives of pharmacal research 2026 Mar;49(3):357-374
Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis.
Guo S, Fu W, Wang Y, Liu Q, Li J, Guo K, Zhang H
CNS neuroscience & therapeutics 2026 Mar;32(3):e70807
CNS neuroscience & therapeutics 2026 Mar;32(3):e70807
Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
Gong Q, Zhao W, Wang T, Pan Y, Cui C, Qu Y, Zhou X
The Journal of biological chemistry 2026 Mar;302(3):111182
The Journal of biological chemistry 2026 Mar;302(3):111182
Restricting intracellular Salmonella proliferation by coordinating p-TBK1 mediated mitophagy and xenophagy.
Li J, Yang Y, Ge Y, Zhang X, Liu H, Chen Y, Yang Y, Wu Z
Autophagy 2026 Mar;22(3):445-467
Autophagy 2026 Mar;22(3):445-467
TIGAR promotes osteogenic differentiation and ameliorates glucocorticoid-induced osteoporosis via autophagy-Nrf2-ROS axis.
Zhang D, Ding F, Wang Y, Cheng J, Zhu J, Liu S, Wang X, Qin ZH, Ren L
Genes & diseases 2026 Mar;13(2):101735
Genes & diseases 2026 Mar;13(2):101735
Thymoquinone attenuates poly(I:C)-induced cellular stress via PKR/ATF4/CHOP signaling and autophagy modulation in human alveolar epithelial cells.
Kolac UK, Goker Bagca B, Donmez Yalcin G, Taskiran MI, Kara SS
Toxicology in vitro : an international journal published in association with BIBRA 2026 Mar;111:106165
Toxicology in vitro : an international journal published in association with BIBRA 2026 Mar;111:106165
Translation of expanded CGG repeats in LRP12 associated oculopharyngodistal myopathy.
Li C, Daw JA, Pittman SK, Maltby CJ, Sakurai H, Todd PK, Weihl CC
Acta neuropathologica communications 2026 Mar 6;14(1)
Acta neuropathologica communications 2026 Mar 6;14(1)
Polystyrene Nanoplastics induced placental toxicology by activating Keap1-mediated ferroptosis via METTL3-dependent m6A methylation.
Chen Y, Liu Y, Zhang M, Li S, Yan Y, Yin C
Cell biology and toxicology 2026 Mar 3;42(1)
Cell biology and toxicology 2026 Mar 3;42(1)
Resveratrol Attenuates Liver Inflammation in Non-Alcoholic Fatty Liver Disease by Activating PINK1-Mediated Mitophagy.
Tan S, Yu R, Sun L, Shen M, Pedroso JF, Chacón OC, Li C, Zhao W
Animals : an open access journal from MDPI 2026 Mar 27;16(7)
Animals : an open access journal from MDPI 2026 Mar 27;16(7)
Didymin alleviates neuropathic pain by targeting RKIP-mediated NF-κB/NLRP3 crosstalk to inhibit pyroptosis and neuroinflammation.
Wang K, Guo A, Chen Y, Xia C, Liang J, Zhang X, Huang L, Zhang Z, Wu L, Yan H
Journal of ethnopharmacology 2026 Mar 25;359:121046
Journal of ethnopharmacology 2026 Mar 25;359:121046
Annexin A1 triggers autophagy to orchestrate radioiodine resistance in thyroid cancer via upregulating HMGB1.
Wang X, Guo L, Yuan M, Feng Y, Wang Y, Jin G
Cancer cell international 2026 Mar 23;26(1)
Cancer cell international 2026 Mar 23;26(1)
Cannabigerol Reduces Lipid Peroxidation Influencing Oxidative Stress and Inflammation Signaling Pathways in Melanocytes Exposed to UVA Radiation.
Jarocka-Karpowicz I, Gęgotek A, Žarković N, Maruška A, Skrzydlewska E
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47793
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47793
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein.
Zhao W, Kong N, Lan D, Zhang Y, Liu H, Liu C, Qin W, Yang X, Liu T, Tong W, Yu H, Zheng H, Tong G, Xie S, Xing G, Shan T
Virologica Sinica 2026 Mar 20;
Virologica Sinica 2026 Mar 20;
A germline-specific vesicular structure licenses mRNA activation during spermiogenesis and is hijacked in gastric cancer.
Liu M, Wang Z, Li Y, Xie Q, Xiao Z, He X, Wang G, Gao Y, Zhang Y, Zheng L, Xia X, Chen L, Dong Y, Liu S, Zhang X, Xu C, Bian S, Yuan Y, Wu H, Cao Y, Zhang J, Hua R, He X
Science bulletin 2026 Mar 2;
Science bulletin 2026 Mar 2;
Overexpression of As3mt Attenuates Sodium Arsenite Induced Ferritinophagy and Hepatic Lipid Accumulation in Mice.
Bao JC, Yang Y, Wang Y, Xie FS
Biological trace element research 2026 Mar 17;
Biological trace element research 2026 Mar 17;
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
Wang L, Zhang W, Wang Z, Zhang W, Zhang L, Li J, Mao Z, Zhang J, Liang T, Ge R, Zhang Y, Yan C, Zhang J, Liang T
Phytotherapy research : PTR 2026 Mar 17;
Phytotherapy research : PTR 2026 Mar 17;
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Chen SX, Qi X, Zheng XT, Bi ZM, Zhang Y, Wang YM
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Nuclear Localization of Effector BPE159: A Pivotal Mechanism for Intracellular Persistence of Brucella by Hampering Host Autophagy.
Zhang Y, Lyu T, Song S, Zhang Y, Wei C, Liu L, Wang Z, Sun Z, Zhou X, Guo J, Zhang H
Microorganisms 2026 Mar 14;14(3)
Microorganisms 2026 Mar 14;14(3)
Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury.
Xu L, Wang M, Feng Y, Wang S, Qian Y, Jiang W, Xu J, Fang Y, Zhang Y, Chu L
Biomolecules 2026 Mar 13;16(3)
Biomolecules 2026 Mar 13;16(3)
Lipotoxic hepatocyte-derived UBQLN1-enriched small extracellular vesicles activate hepatic stellate cells to promote hepatic fibrosis.
Yang F, Chen Y, Wang Y, Zheng G, Abouelnazar F, Fan L, Wang Y, Yan Y
Autophagy 2026 Mar 13;:1-23
Autophagy 2026 Mar 13;:1-23
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
Liu K, Hong Y, Gao Q, Huang J, Liu L, Li Y, Liang Y, Zhang S, He X, Nie X
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Zheng H, Tian S, Wu L, Jia G, Xiao Y, Yu X, Zuo Q, Zhou R, Min J, Wu Q, Xie H, Luo Q, Wu W
The journal of headache and pain 2026 Mar 11;27(1)
The journal of headache and pain 2026 Mar 11;27(1)
Glaesserella parasuis serotype 5 disrupts the swine respiratory epithelial barrier via NBR1-mediated selective autophagic degradation of Claudin-1.
Wang Q, Song C, Song C, Fang K, Yuan Y, Wang J, Fan H
Veterinary microbiology 2026 Jun;317:111030
Veterinary microbiology 2026 Jun;317:111030
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
Wen Z, Guo Y, Bai R, Liu W, Liang B, Dong C, Zhang Y, Song Y, Wang T, Wang Z, Du J, Ma X, Ding J, Yu Z
Pathology, research and practice 2026 Jun;282:156467
Pathology, research and practice 2026 Jun;282:156467
EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy.
Zhang X, Zhang B, Shi C, Kampan N, Treebupachatsakul W, Pantan R, Narakornsak S, Phatsara M
IBRO neuroscience reports 2026 Jun;20:577-586
IBRO neuroscience reports 2026 Jun;20:577-586
Usenamine a potentiates anti-CRC activity of sorafenib by inducing autophagy and inhibiting YAP pathway through targeting SOD2.
Zhuge W, Kuang J, Kuang K, Rao M, Jian D, Lin H, Li Z, Li S, Zheng Y, Cho N, Li X, Cui R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158086
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158086
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL
Synthetic and systems biotechnology 2026 Jun;12:197-208
Synthetic and systems biotechnology 2026 Jun;12:197-208
Bergapten ameliorates osteoarthritis progression by inhibiting the PI3K/AKT/mTOR pathway to activate mitophagy and suppress pyroptosis.
Huang X, Zhang J, Chen N, Huang B, Zhao Y, Zhu C, Zhang S, Xia J, Zhang L, Liu L, Lin X
International immunopharmacology 2026 Jun 15;179:116565
International immunopharmacology 2026 Jun 15;179:116565
A foam cell-targeted lipophagy restoration strategy stabilizes vulnerable atherosclerotic plaques.
Li H, Qin Y, Zhang J, Guo X, Hu X, Sun D, Zhao Y, Bernardini S, Xu D, Jiang P, Zhang H, Luo Y
Bioactive materials 2026 Jul;61:879-899
Bioactive materials 2026 Jul;61:879-899
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy.
Zhang Y, Shen X, Shen Y, Wang C, Yu C, Han J, Cao S, Qian L, Ma M, Huang S, Wen W, Yin M, Lei QY
Nature 2026 Jan;649(8098):1022-1031
Nature 2026 Jan;649(8098):1022-1031
The Neuroprotective Role of Ginsenoside Rg1 Against Cerebral Ischemia-Reperfusion Damage Through Inhibition of Mitophagy via Blocking Mitophagosome-Lysosome Fusion.
Ai L, Ren H, Wang Y, Liu M, Qiu Y, Feng J, Dai R, Fu W, Wang Y, Xi Z, Xu H, Wang F
Cell proliferation 2026 Jan;59(1):e70071
Cell proliferation 2026 Jan;59(1):e70071
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
Hu P, Chen Y, Long P, Zhang A, Lan X, He Y, Li G, Li S
International endodontic journal 2026 Jan;59(1):134-152
International endodontic journal 2026 Jan;59(1):134-152
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Gao S, Yao W, Yang J, Liu Y, Pei Z
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
Selaginella Tamariscina extract reduces UVA-induced skin photodamage via regulating apoptosis and autophagy by AKT phosphorylation.
Zhao N, Zhou X, Li Z, Liang L, Bao J, Chen X, Shu P, Zhong J
Journal of photochemistry and photobiology. B, Biology 2026 Jan;274:113343
Journal of photochemistry and photobiology. B, Biology 2026 Jan;274:113343
Parkin protects against traumatic brain injury through regulating mitochondrial quality control.
Wu X, Lv W, Chen H, Fu Y, Fei X, Dou Y, Luo P, Yu Y, Niu Z, Huan Y, Wei J, Zhang J, Ji C, Li S, Zhou Y, Yuan Y, Chao W, Luo Y, Xie C, Qiang Y, Chang H, Gao D, Li X
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00846
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00846
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Han S, Pu Y, Liu Z
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.
Song YN, Zhang F, He Y, Li YH, Hu FY, Gao Y, Zong SY, Wang Y, Gao XY, Tang Q, Jiang XM, Tong FZ, Yan LP, Wei F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157706
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157706
Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux.
Cao X, Li Y, Guo B, Liu Y, Wang B, Wang H, Lu J, Wei L, Gao Y, Guo Y, Wu T
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 8;49(1):21
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 8;49(1):21
Opn3 Drives Blue-Light-Induced Reduction in Lipid Droplets and Antiviral Defense.
Wu Q, Liu H, Liang H, Jiang X, Qin Y, Liang S, Wang J, Liu K
Biomolecules 2026 Jan 8;16(1)
Biomolecules 2026 Jan 8;16(1)
Targeting endolysosomal acidification inhibits poxvirus entry and replication.
Xu S, Zhang X, Li C, Zhang Z, Wang X, Wan C, Wang P, Lv Y, He Y, Chan FK, Liu Z
Cell communication and signaling : CCS 2026 Jan 28;24(1)
Cell communication and signaling : CCS 2026 Jan 28;24(1)
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Toriola MA, Timlin E, Bulbule S, Reyes A, Adedeji OM, Gottschalk CG, Barua A, Arnold LA, Roy A
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Outer membrane vesicles secreted by avian pathogenic Escherichia coli promote its survival within macrophages and systemic infection by inducing endoplasmic reticulum stress-mediated autophagy flux blockade.
Cui T, Li Z, Gao J, Miao Z, Li F, Shao Y, Wang Z, Sun J, Song X, Qi K, Tu J
Veterinary research 2026 Jan 27;57(1):34
Veterinary research 2026 Jan 27;57(1):34
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Xiao M, Guo W, Zeng R, Wu S, Jin X
Nature communications 2026 Jan 16;17(1):1740
Nature communications 2026 Jan 16;17(1):1740
Acacetin Attenuates Lysophosphatidylcholine-Induced Vascular Smooth Muscle Cell Injury via Sirt1-Nrf2/p62 Signaling Axis.
Li YD, Wu Y, Zhou TL, Yuan Q, Li GR, Wu WY, Wang Y, Li G
Biomedicines 2026 Jan 15;14(1)
Biomedicines 2026 Jan 15;14(1)
rIL-22 Alleviates Severe Acute Pancreatitis and Secondary Multiple Organ Injury Induced by Caerulein in Mice.
Yang H, Sun W, Cheng P, Zhou F, Mo R, Xu Q, Zhu C, Cao R, Jing H, Wang H, Jin B, Yu F, Ge L, Xu H
Inflammation 2026 Jan 14;49(1):47
Inflammation 2026 Jan 14;49(1):47
tRNA m(2)G methyltransferase complex THUMPD3-TRMT112 promotes pancreatic cancer progression and autophagy via modulating TFEB translation.
Yuan W, Li S, Xi Y, Tian R, Liu Y, Chen X, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Qin W, Yan C, Chen XZ, Zhou C, Tang J
Molecular cancer 2026 Jan 13;25(1)
Molecular cancer 2026 Jan 13;25(1)
In Situ Reprogramming of Senescent Microenvironment via Augmentation of Endogenous Senolytic Actions for Advanced Atherosclerosis Management.
Wang Z, Chen X, Xu Y, Guo X, Liu X, Dai X, Lu J, Qi J, Zheng T, Zhang L, Ma L, Wang S, Yang G, Lu G, Wang F, Zhou Q, Sheng J, Zhang L
ACS nano 2026 Jan 13;20(1):1249-1266
ACS nano 2026 Jan 13;20(1):1249-1266
Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy.
Xie X, Liu C, Liu X, Hou L, Zhang Y, Huang L, Peng W, Liu Y
Scientific reports 2026 Jan 13;16(1):5155
Scientific reports 2026 Jan 13;16(1):5155
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
Yin H, Wei Y, Han Z, Li Z, Liu K, Zhu L
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
STING deficiency alleviates ischemia-reperfusion injury via JAK2/STAT3-mediated macrophage polarization and autophagy.
Zhang Y, Jing Y, Liao H, Ding K, Zhang L, Liao S, Kadier T, Chen R, Meng Q
International immunopharmacology 2026 Jan 1;168(Pt 1):115784
International immunopharmacology 2026 Jan 1;168(Pt 1):115784
Heme oxygenase 1 (HO-1) is a drug target for reversing cisplatin resistance in non-small cell lung cancer.
Mei J, Tian HX, Zhang XY, Chen YS, Wang LY, Zhang Z, Zhang YL, Rong DC, Zeng J, Dong M, Gao Y, Yin JY, Wu HJ, Wang PY, Zhang W
Journal of advanced research 2026 Feb;80:1121-1137
Journal of advanced research 2026 Feb;80:1121-1137
Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following Porphyromonas endodontalis Infection.
Lei S, Li J, Wang XC, Yu S, Wang AC, Yang N, Gao MC, Chen X
International endodontic journal 2026 Feb;59(2):225-237
International endodontic journal 2026 Feb;59(2):225-237
Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease.
Pan Y, Yang F, Wang L, Yang T, Du G, Xu C, Yang H, Yu M, Xiao W
International journal of molecular medicine 2026 Feb;57(2)
International journal of molecular medicine 2026 Feb;57(2)
STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma.
Hu H, Zhang H, Han S, Chen J, Xie Y
International journal of molecular medicine 2026 Feb;57(2)
International journal of molecular medicine 2026 Feb;57(2)
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
Li L, Dan M, Li S, Cui X, Bao S, Luo S, Cao J
Toxicology 2026 Feb;520:154368
Toxicology 2026 Feb;520:154368
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR
Molecular medicine reports 2026 Feb;33(2)
Molecular medicine reports 2026 Feb;33(2)
SIX2-Mediated Microglial M2 Polarization and Exosomal miR-3470b Delivery Protect Dopaminergic Neurons in Parkinson's Disease.
Kan JS, Cao XY, Ye YX, Huang XX, Sun GJ, Gao J
CNS neuroscience & therapeutics 2026 Feb;32(2):e70756
CNS neuroscience & therapeutics 2026 Feb;32(2):e70756
CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy.
Gao X, Yu Y, Sun J, Zhao H, You Y, Shi X, Wang K, Hong S, Xiong X, Huang C, Zhang H, Jiang G
PLoS biology 2026 Feb;24(2):e3003647
PLoS biology 2026 Feb;24(2):e3003647
Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.
Tong B, Zhang X, Zhu D, Wang Y, Wei J, Ou Z, Liang H, Xu H, Zhang Z, Lei J, Zhou X, Wu D, Song Y, Wang K, Feng X, Tan L, Liao Z, Yang C
EMBO molecular medicine 2026 Feb;18(2):759-794
EMBO molecular medicine 2026 Feb;18(2):759-794
Cannabidiol alleviates methamphetamine-induced autophagy and oxidative stress by suppressing sigma 1 receptor expression.
Li Y, Liu L, Miao L, Zhang Y, Li XD, Sun T, Zeng XF, Huang J, Liu JX
Cellular signalling 2026 Feb;138:112280
Cellular signalling 2026 Feb;138:112280
MSMP promotes an aberrant phenotype of fibroblast-like synoviocytes in rheumatoid arthritis by blocking autophagy via the RUNX1/GPR137B axis.
Wang C, Zeng Y, Tan P, Yuan S, Li W, Ye J, Chen M, Lao M, Xiao Y, Liang L, Xu H, Cai X
Arthritis research & therapy 2026 Feb 3;28(1)
Arthritis research & therapy 2026 Feb 3;28(1)
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Tang C, Teng W, Jiang Y, Wu Y
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin.
Jeong H, Qin Y, Xu F, Trajkovic K, Kim MJ, Marotta N, Hamada K, Allada R, Yang S, Krainc D
JCI insight 2026 Feb 23;11(4)
JCI insight 2026 Feb 23;11(4)
SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis.
Lin YC, Lin YW, Wang RH, Chang CJ, Pang JY, Hsiao MC, Wang HM, Wu SY, Chiang CM, Chao JI
Journal of advanced research 2026 Feb 21;
Journal of advanced research 2026 Feb 21;
Neural stem cell-derived exosomal PA2G4 induces ANXA2 degradation to promote mitophagy and alleviate neuronal oxidative stress in cerebral ischemia/reperfusion.
Dai M, Lu T, Li J, Yu H
Apoptosis : an international journal on programmed cell death 2026 Feb 20;31(3)
Apoptosis : an international journal on programmed cell death 2026 Feb 20;31(3)
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
Huang X, Meng Y, Song J, Zhu Y, Li J, Xi Y, Peng X, Xiong Y
iScience 2026 Feb 20;29(2):114734
iScience 2026 Feb 20;29(2):114734
Melatonin ameliorates copper accumulation-induced cognitive impairment in Wilson disease via activation of the SIRT3/FOXO3α signaling pathway.
Wang L, Wu L, Wang T, Yue Y, Jiang Z, Jiang P, Zhou H, He L, Xia Z, Song Y, Wang F, Xiao X, Han H
Neuropharmacology 2026 Feb 15;284:110779
Neuropharmacology 2026 Feb 15;284:110779
Negative feedback regulation of STING signaling by TAX1BP1-directed Golgiphagy.
Suklabaidya S, Mohanty S, Reider IE, White J, Colter D, McCormick SM, Shembade N, Choi YB, Norbury CC, Harhaj EW
Nature communications 2026 Feb 11;17(1)
Nature communications 2026 Feb 11;17(1)
miR-17-5p inhibits classical swine fever virus replication by targeting the PKD2-regulated AMPK/mTOR autophagy pathway.
Wang X, Yang S, Xie L, Qi S, Gao L, Li Y, Li Q, Bi J, Liu J, Li Y, Yin G
Virulence 2026 Dec;17(1):2629657
Virulence 2026 Dec;17(1):2629657
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Zhang J, Duan K, Liu Q, Chen S, Zheng H, Liu Y, Qian J, Yin M, Liu J, Li J, Li Z, Chen M, Huang X, Lin F, Gao M, Liao L
Bioactive materials 2026 Aug;62:1-16
Bioactive materials 2026 Aug;62:1-16
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Jiashu Z, Jingbao L, Hua F, Meiqi S, Jing L, Mengyao W, Wei Z
Cellular signalling 2026 Aug;144:112517
Cellular signalling 2026 Aug;144:112517
Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.
Zhao X, Zhang R, Ma Y, Yu T, Li J, Liu A, Hu J, Wu J, Zhang L, Ye M, Wu B, Dang Y
Bioorganic chemistry 2026 Aug 5;177:109885
Bioorganic chemistry 2026 Aug 5;177:109885
MeCP2 dysregulation inhibits mitophagy and impairs neural development in cortical organoids.
Zhou J, Liu Y, Jing X, Peng H, Li F, Cao L, Li W, Li R, Zhang J, Wang X, Lian J, Tong D, Huang C
Journal of advanced research 2026 Apr;82:429-448
Journal of advanced research 2026 Apr;82:429-448
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Yang Z, Zeng A, Yu B, Xie C, Zhu W, Liu H, Gu C, Fu M
Biochemical genetics 2026 Apr;64(2):2416-2447
Biochemical genetics 2026 Apr;64(2):2416-2447
Oligodendrocyte Inclusion Pathology in Fragile X-Associated Tremor/Ataxia Syndrome.
McLennan Y, Aliashrafzadeh H, Zirkelbach-Ngai F, McKenzie F, Dufour BD, Becerra-Hernández LV, Escobar AS, Tassone F, Hagerman P, Hagerman R, Martínez-Cerdeño V
Movement disorders : official journal of the Movement Disorder Society 2026 Apr;41(4):1041-1046
Movement disorders : official journal of the Movement Disorder Society 2026 Apr;41(4):1041-1046
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
Xu J, Li Y, Xu J, He R, Jiang F, Lu J, Xu T, Wang J, Zhang C
Materials today. Bio 2026 Apr;37:102926
Materials today. Bio 2026 Apr;37:102926
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
Zhu C, Jia S, Wang J, Gao F, Lin Y, Nie A, Guo Z, Zhou Z, Xu B, Lei H
Materials today. Bio 2026 Apr;37:102828
Materials today. Bio 2026 Apr;37:102828
ANKFY1 suppresses PDCoV replication by degrading viral nsp8 protein via p62-dependent selective autophagy.
Xu Y, Zhang Y, Zhu H, Yu X, Lou J, Liu M, Liu G, Bai J, Jiang P, Yang Z, Wang X
Veterinary microbiology 2026 Apr;315:110927
Veterinary microbiology 2026 Apr;315:110927
TNFAIP8 targets ATG3 to regulate autophagy and participate in the molecular mechanism of ankylosing spondylitis.
Zhao Y, Ni M, Zhao H, Ren Y, Li Z, Wu H, Xu L, Li G, Pan F
Immunology letters 2026 Apr;278:107124
Immunology letters 2026 Apr;278:107124
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Wang X, Sun H, Xiao W, Zhang Y, Lu X, Gong Z, Li D, Liu S, Xia X, Wang H, Shao M, Xu G, Ma X
Non-coding RNA research 2026 Apr;17:112-127
Non-coding RNA research 2026 Apr;17:112-127
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
Li HF, Zhang CJ, Shi YN, Zhu N, Yang Q, Long JP, Liang YT, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.
Ye J, Wang D, Pang H, Liu Q, Pan Z, Wang L, Liu B, He G
European journal of medicinal chemistry 2026 Apr 5;307:118633
European journal of medicinal chemistry 2026 Apr 5;307:118633
Emerging Alternaria Toxins Drive LX-2 Cells Transdifferentiation into Myofibroblasts for Liver Fibrosis and CotA Detoxification.
Lin H, Jia B, Chang B, Sun F, Tan Y, Tian Y, Fan Y, Liang J, Wu A
Journal of agricultural and food chemistry 2026 Apr 29;74(16):13162-13178
Journal of agricultural and food chemistry 2026 Apr 29;74(16):13162-13178
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Tian P, Du Q, Zeng F, Chen J, Wang P, Zhang L, Li Y
Molecular biology reports 2026 Apr 22;53(1)
Molecular biology reports 2026 Apr 22;53(1)
Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity.
You Z, Kim J, Guo C, Hu H, Chapman NM, Meng X, Shi H, Wang Y, Guy C, Kc A, Li J, Saravia J, Palacios G, Rankin S, Robinson CG, Chi H
Science (New York, N.Y.) 2026 Apr 2;392(6793):eadv6582
Science (New York, N.Y.) 2026 Apr 2;392(6793):eadv6582
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Pang P, Chen J, Li Q, Su Z, Lin J, Zeng Y, Zhang W, Xiao Z, Chen Z, Liu Z, Lin Y, Zheng G, Yu W, Xie Z
Journal of advanced research 2026 Apr 17;
Journal of advanced research 2026 Apr 17;
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Dong Y, Yin X, Shan X, Hu Y, Zhu C
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Deficiency in beclin1 alleviates doxorubicin-induced liver injury through inhibiting ferroptosis and autophagy.
Zhang L, He Y, Zhao A, Han H, Li Y, Li L, Zhang Y, Gao Q, Ye H
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2026 Apr 15;1274:124971
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2026 Apr 15;1274:124971
STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates.
Haws W, Dao TP, Varner B, Jones HB, Brown MP, Castañeda CA
bioRxiv : the preprint server for biology 2026 Apr 15;
bioRxiv : the preprint server for biology 2026 Apr 15;
Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.
Liu X, Liu S, Xu G, Chen W, Shi Y, Wang G, Cao Y, Lu G, Ning Y, Zhao Y
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
Li X, Ren B, Zhang D, Dan M, Liu D, Zhang Z, Zhao J, Nan Y, Hiscox JA, Stewart JP, Zhu Z, Zhao Q, Sun Y
Autophagy 2026 Apr 11;:1-20
Autophagy 2026 Apr 11;:1-20
USP2 Attenuates Spermatogenic Cell Apoptosis Via PINK1/Parkin-Dependent Mitophagy in Varicocoele: A Functional Study.
Yao RJ, Xiao H, Zheng JH, Lin B, Liao SJ, He HH, Xu N, Zhou HL
Andrology 2026 Apr 10;
Andrology 2026 Apr 10;
T-2 toxin induces ER stress-dependent liver injury via mitophagy-mediated ER-phagy suppression: Berbamine blocks SNARE complex for hepatoprotection.
Xu Q, Deng L, Xu J, Wu Z, Lin R, Deng Y, Wen J
Journal of hazardous materials 2026 Apr 1;507:141693
Journal of hazardous materials 2026 Apr 1;507:141693
EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy.
Pang H, Wu F, Zhang YU, Zhang N, Wang C, Li Q, He GU, Zhang P
Oncology research 2025;33(2):443-464
Oncology research 2025;33(2):443-464
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
Zheng Z, Chen J, Xue X, Ma X, Zhang S, Wang M, Xue Y, Jia Y
International journal of biological sciences 2025;21(9):4215-4230
International journal of biological sciences 2025;21(9):4215-4230
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
Xie Y, Tian Y, Huang J, Deng W, Li X, Liu Y, Liu H, Gao L, Xie Q, Yu Q
International journal of biological sciences 2025;21(8):3505-3526
International journal of biological sciences 2025;21(8):3505-3526
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274
International journal of biological sciences 2025;21(3):1259-1274
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Qi M, Wang Q, Sun R, Cheng Z, Li M, Fan X, Bai F, Yu J
Cardiovascular therapeutics 2025;2025:9549175
Cardiovascular therapeutics 2025;2025:9549175
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
Zou X, Chen W, Shao Y, Shi T, Ke Y
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Wang J, Qi X, Zhao W, Hao Z, Wang K, Li Y, Wang Y, Zhang Y
PloS one 2025;20(8):e0329847
PloS one 2025;20(8):e0329847
Endotoxin tolerance inhibits NLRP3 inflammasome activation in macrophages of septic mice by restoring autophagic flux through TRIM26.
Yang Y, Wu S, Lin M, Xie X, Shi H, Chen Y, Li S, Jiang Y, Zheng S, Shen C, Yang N, Lu M
Open medicine (Warsaw, Poland) 2025;20(1):20251231
Open medicine (Warsaw, Poland) 2025;20(1):20251231
Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.
Mao Y, Du X, Wang W, Dong T, Zhu M, Niu J, Li M, Jiang J, Han L, Yang X
International journal of nanomedicine 2025;20:11081-11097
International journal of nanomedicine 2025;20:11081-11097
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Ding F, Zhang W, Liu T, Rong X, Cui Y, Meng L, Wang L, Liu B, Li M
Drug design, development and therapy 2025;19:2173-2188
Drug design, development and therapy 2025;19:2173-2188
Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury.
Yan L, Zhou X, Li Q, Hong H, Wu C, Gao YJ, Cui Z, Xu G
Frontiers in cellular neuroscience 2025;19:1622825
Frontiers in cellular neuroscience 2025;19:1622825
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
Zhang S, Yan M, Liang P, Zhang Y, Liu J, Huang H, Li G, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Wang A, Zhou Y, Deng Z, Duan Y, Dai Z, Jiang D
Frontiers in immunology 2025;16:1719525
Frontiers in immunology 2025;16:1719525
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
Yu J, Kang X, Chang R, Zhang C, Yang S, Chen L, Wang X, Hu B, Wang Z, Gong L, Liu L
Frontiers in pharmacology 2025;16:1704023
Frontiers in pharmacology 2025;16:1704023
Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxin.
Wu JX, Wu YL, Li MF, Liu N, Liu Y, Huang YP, Gan Y, Wang XY, Chai HS, Xu J, Xi Q, Guo XR, Sheng HM, Shen TT, Zhang Q
Frontiers in pharmacology 2025;16:1694242
Frontiers in pharmacology 2025;16:1694242
Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy.
Liu Y, Zhou Y, Chen J, Jin J, Wang X, Wang X, Zhang J, Li J, Zhang J, Zhu L, Xu GT, Bi Y, Ou Q, Jin C
Frontiers in endocrinology 2025;16:1652898
Frontiers in endocrinology 2025;16:1652898
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Cao Y, Zhou J, Quan H, Li W, Li T, Wang L
Frontiers in immunology 2025;16:1597222
Frontiers in immunology 2025;16:1597222
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Zhang P, Jin M, Zhang L, Cui Y, Dong X, Yang J, Zhang J, Wu H
Frontiers in pharmacology 2025;16:1540835
Frontiers in pharmacology 2025;16:1540835
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
Wu T, Xiao Z, Su B, Yan Z, Zhao Y, Huang C, Zhou L, Tian H, Zhang G
American journal of cancer research 2025;15(6):2826-2842
American journal of cancer research 2025;15(6):2826-2842
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
Liu R, Li X, Xu J, Yan L, Hu K, Shi M, Zhang Y, Zhao Y, Fan Y, Wang G, Guo Y, Feng Y, Liu P
Theranostics 2025;15(17):9091-9113
Theranostics 2025;15(17):9091-9113
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
Zhu G, Zheng L, He W, Chen X, Huang S, Jin M, Zhang Y
Frontiers in oncology 2025;15:1743808
Frontiers in oncology 2025;15:1743808
The aggrephagy-related gene TUBA1B influences clinical outcomes in glioma patients by regulating the cell cycle.
Sun Z, Huang P, Lin J, Jiang G, Chen J, Liu Q
Frontiers in oncology 2025;15:1531465
Frontiers in oncology 2025;15:1531465
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Fang P, Li S, Lu ZQ, Xia DL, Xu MM, Pan JJ, Fu L, Sun GY, You QH
Burns & trauma 2025;13:tkaf056
Burns & trauma 2025;13:tkaf056
Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels.
Li J, Wu G, Su H, Liang M, Cen S, Liao Y, Zhou X, Xie G, Deng Z, Tan W, Li Y, Xiao W, Liu L, Zhang J, Zheng Z, Deng Y, Huang Y, Shi X, Liu Y, Zhang G, Chen X
Redox biology 2025 Sep;85:103672
Redox biology 2025 Sep;85:103672
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Wan J, Cai X, Liao Z, Liu Y, Liu Q, Zhang C, Long F
IUBMB life 2025 Sep;77(9):e70048
IUBMB life 2025 Sep;77(9):e70048
Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction.
Perera ND, De Silva S, Tomas D, Cuic B, Turner BJ
Glia 2025 Sep;73(9):1860-1882
Glia 2025 Sep;73(9):1860-1882
ADSC-EVs Activate Autophagy Via the AKT/FOXO1 Pathway to Inhibit Tendon Fibrosis.
Zhang AD, Liu HC, Zhang TT, Li XQ, Wu Y, Guo YJ, Li RW, Xu B, Jiang ZT, Li ZZ
The American journal of sports medicine 2025 Sep;53(11):2618-2632
The American journal of sports medicine 2025 Sep;53(11):2618-2632
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation.
Pu Q, Gao F, Xiao Y, Wu J, Wang C, Mo X, Zhang Z, Zheng R, Wu D
Toxicology 2025 Sep;516:154193
Toxicology 2025 Sep;516:154193
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Shafik MS, El-Tanbouly DM, Bishr A, Soubh AA, Attia AS, Muhammad RN
Toxicology and applied pharmacology 2025 Sep;502:117423
Toxicology and applied pharmacology 2025 Sep;502:117423
Promoter polymorphism rs510432 in ATG5 affects the susceptibility of noise-induced hearing loss by altering the binding of C/EBPβ.
Miao L, Qu M, Xue Y, Li X, Yin L, Pu Y
Hearing research 2025 Sep;465:109340
Hearing research 2025 Sep;465:109340
miR-545-x regulates hypoxia-induced proliferation, apoptosis and autophagy of yak coronary smooth muscle cells by antagonizing DNA damage inducible transcript 4.
Yang S, Cui Y, Yu S, He J, Ma R, Niu Y
International journal of biological macromolecules 2025 Sep;321(Pt 2):146226
International journal of biological macromolecules 2025 Sep;321(Pt 2):146226
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
Huang Y, Xu F, Wang L, Mei S, Zhao F, Wang L, Xie Y, Wei L, Hu Y, Gao Z, Xue T, Fang J, Guo F
EMBO reports 2025 Sep;26(18):4607-4630
EMBO reports 2025 Sep;26(18):4607-4630
PINK1-mediated mitochondrial autophagy protects lens epithelial cells by reducing ROS and apoptosis.
Liu X, Wang M, Ji Z, Zhu X, Tian J, Chen Y, Cai J, Dong M, Li Z
Experimental eye research 2025 Sep;258:110437
Experimental eye research 2025 Sep;258:110437
R406 and its structural analogs reduce SNCA/α-synuclein levels via autophagic degradation.
Zhong C, Gao X, Chen Q, Guan B, Wu W, Ma Z, Tao M, Liu X, Ding Y, Fei Y, Liu Y, Lu B, Li Z
Autophagy 2025 Sep;21(9):1945-1961
Autophagy 2025 Sep;21(9):1945-1961
Resveratrol ameliorates streptozotocin induced renal inflammation and promotes autophagy by mediating the SphK1 pathway via Sirt1 in Wistar rats.
Feng F, Li S, Shi J, Chen W, Deng Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115588
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115588
EPOR activation attenuates colitis via enhancing LC3B-dependent apoptotic cell clearance.
Liu X, Zhang LY, Zhang YG, Duan TH, Ding Y, Pan CL, Xu L, Qian C, Ni M, Zhang ZY
Immunology 2025 Sep;176(1):33-48
Immunology 2025 Sep;176(1):33-48
Energy metabolism disturbance induced by atorvastatin exposure on yellowstripe goby (Mugilogobius chulae) larvae based on transcriptome and metabolome analysis.
Zhao Y, Wang Y, Gong W, Duan C, Ren J, Zhang H, Nie X
Journal of environmental sciences (China) 2025 Sep;155:475-487
Journal of environmental sciences (China) 2025 Sep;155:475-487
Tectorigenin attenuates myocardial damage by doxorubicin-induced ferroptosis by activating the p62-Keap1-Nrf2/HO-1/GPX4 axis.
Xie L, Xiao S, Zhou Q, Chen W, Hu Z, Li Y, Liu Y, Ma X, Li Y
Journal of traditional and complementary medicine 2025 Sep;15(5):573-581
Journal of traditional and complementary medicine 2025 Sep;15(5):573-581
Magnolin Promotes PINK1-Parkin-mediated Mitophagy in Diffuse Large B-cell Lymphoma Cells via PPAR-γ Pathway.
Zhou X, Guo Q, Qiao Q, Fang X, Jiang Y, Wang X, Hu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157059
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157059
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
Qi Y, Xie S, Chen J, Zhang C, Ma X, Yu Y, Yu X, Wang Y
The Journal of nutritional biochemistry 2025 Sep;143:109954
The Journal of nutritional biochemistry 2025 Sep;143:109954
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Shen Y, Wang L, Guo Z, Wang J, Zhang R, Tang C, Wu J
Cellular signalling 2025 Sep;133:111873
Cellular signalling 2025 Sep;133:111873
Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.
Su Z, Shu H, Huang X, Ding L, Liang F, Xu Z, Zhu Z, Chen M, Wang X, Li G, Xia H, Cao Q, Zhang W, Xu P, Yang X
Cellular and molecular life sciences : CMLS 2025 Sep 6;82(1):337
Cellular and molecular life sciences : CMLS 2025 Sep 6;82(1):337
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
Ma C, Wang J, Cui S, Xu R
European journal of pharmacology 2025 Sep 5;1002:177859
European journal of pharmacology 2025 Sep 5;1002:177859
Melatonin attenuates ischemia-reperfusion-induced acute kidney injury by regulating abnormal autophagy and pyroptosis through SIRT1-mediated p53 deacetylation.
Sun C, Liu J, Li H, Yan Y
International immunopharmacology 2025 Sep 23;162:115092
International immunopharmacology 2025 Sep 23;162:115092
Type B Fibers: A Novel Ultrastructural Biomarker for Cognitive Impairment in Neuronal Intranuclear Inclusion Disease.
Zhou B, Zhong S, Lian Y, Liang J, Huang L, Ding J, Wang X
Brain sciences 2025 Sep 23;15(10)
Brain sciences 2025 Sep 23;15(10)
LINC01018 attenuates hepatic lipid accumulation by inducing autophagy via DHX9 pathway in alcohol-associated liver disease.
Ni B, Yang F, Zhao L, Li L, Liang X, Xu R, Xu Y, He Y, Yuan C, Chen W, Zhang Q
International journal of biological macromolecules 2025 Sep 2;328(Pt 1):147298
International journal of biological macromolecules 2025 Sep 2;328(Pt 1):147298
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Yang R, Zhan Y, Deng Z, Zhang J, Chen S, Zhang Y, Fu H, Meng X, Wu J, Gu Y, Huang Q, Wang C, Xie J
Redox biology 2025 Oct;86:103793
Redox biology 2025 Oct;86:103793
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
Ye G, Sun X, Li J, Pu M, Zhang J
Journal of advanced research 2025 Oct;76:731-744
Journal of advanced research 2025 Oct;76:731-744
IRGM Inhibits the AKT/mTOR Signaling Pathway by Interacting with TRIM21 to Alleviate Sepsis-Induced Acute Lung Injury.
Guo N, Xia Y, He N, Zhang L, Liu J
Inflammation 2025 Oct;48(5):3282-3299
Inflammation 2025 Oct;48(5):3282-3299
SNX10 enhances HCoV-OC43 infection by facilitating viral entry and inhibiting virus-triggered autophagy.
Li H, Guo H, Rong B, Li H, Wu W, Yang C, Liu S
Virologica Sinica 2025 Oct;40(5):755-768
Virologica Sinica 2025 Oct;40(5):755-768
Effect of activated autophagy on an animal model of vestibular migraine-like attacks.
Li H, Huang Y, Chen Q, Zhai Q, Zhang C, Yu Q, Chen S, Ying C, Pan Y
Experimental neurology 2025 Oct;392:115366
Experimental neurology 2025 Oct;392:115366
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
Yaxian L, Xiaodong W, Futao M, Huizhen W, Chuansheng W, Mengdi M, Bo Y, Yida L, Xin X, Ziqing F, Mingdian L, Yuxian S, Yongxiang L
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
ER‑α36 knockdown is associated with lysosomal dysfunction and proliferation inhibition in liver cancer cells.
He H, Wang X, Wei Z, Wang A, Fang X, He H, Wu Z, Shu X, Sun B, Chen Q, Huang X, Zhou H, Liu Y, Fu Z
Molecular medicine reports 2025 Oct;32(4)
Molecular medicine reports 2025 Oct;32(4)
The Matrine Derivative MASM Alleviates LPS-Induced Depressive-Like Behavior in Mice by Modulating Hippocampal Inflammation, Oxidative Stress, and Autophagy.
Li CR, Xu ZY, Sun LN, Wu LL, Zeng WF, Zhou J, Lian YJ, Wang Y, Wang YX
Alpha psychiatry 2025 Oct;26(5):47820
Alpha psychiatry 2025 Oct;26(5):47820
Asparaginase and Autophagy Inhibitors Effectively Remove Senescent Cells by Synergistically Limiting Asparagine Supply.
Huang Z, Liu X, Zhou X, Chen K, Diao H, Wang M, Wei J, Li Z, Yang Y, Mao Z, Yu W
Aging cell 2025 Oct;24(10):e70203
Aging cell 2025 Oct;24(10):e70203
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
Gou Y, Ding J, Wang H, Bai R, Wang H, Wang B, Cao Y, Liu J, Cui J, Zhang Z
Free radical biology & medicine 2025 Oct;238:640-652
Free radical biology & medicine 2025 Oct;238:640-652
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610
Free radical biology & medicine 2025 Oct;238:595-610
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Chen W, Liu S, Zhou Y, Liu B, Wang W, Chen C, Lou Z, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Berberine partially ameliorates cardiolipotoxicity in diabetic cardiomyopathy by modulating SIRT3-mediated lipophagy to remodel lipid droplets homeostasis.
Chen W, Jin T, Xie Y, Zhong C, Gao H, Zhang L, Ju J, Cheng T, Li M, Wang H, Yang Z, Deng Q, Du Z, Liang H
British journal of pharmacology 2025 Oct;182(20):5038-5056
British journal of pharmacology 2025 Oct;182(20):5038-5056
Wogonin modulates macrophage polarization and inflammatory signaling through the LSD1-p65 axis to alleviate osteoarthritis.
Cai Z, Lu C, Chen D, Zhang S, Zhou J, Yu S, Wong CK, Jia Z, Jin S, Feng Y, Wu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157149
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157149
Artificial intelligence combined with affinity chromatography discover that 7-Epitaxol promotes autophagy in NSCLC cells by interacting with EGFR: Discovery of novel EGFR antagonist based on DL and CMC.
Bai H, Wu T, Lv Y, Chen W, Jiang Y, Chen F, Su P, Yu H, He L, Li Z, Han S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157127
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157127
LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney disease.
Fan Z, Zhang Y, Yuan L, Gao Y, Tian X, Tian J, Wan J, Li B, Wang X, Wang S, Zhang L, Wang L, Zhou P, Liu W
Cellular signalling 2025 Oct;134:111955
Cellular signalling 2025 Oct;134:111955
The AKT-USP15 axis modulates autophagy in MPP(+)-induced Parkinson's disease model of SN4741 cells.
Wu X, Wen Y, Yuan Y, Bai T, Yang N, Xu L, Ma Y, Su P, Luo W, Li W
Cellular signalling 2025 Oct;134:111879
Cellular signalling 2025 Oct;134:111879
Yogurt alleviates alcohol-induced hepatocyte pyroptosis and inflammation via autophagy/P62/Nrf2/ROS/NLRP3 pathway.
Guan S, Wang Y, Zhang R, Yao X, Lu S, Deng X, Lu J
Journal of dairy science 2025 Oct;108(10):10489-10503
Journal of dairy science 2025 Oct;108(10):10489-10503
Novel Isolongifolenone-Based Caprolactam Derivatives as Potential Anticancer Agents via the p53/mTOR/Autophagy Pathway.
Wang Y, Hu M, Han J, Zhao Y, Xiong B, Li P, Wang S
Molecules (Basel, Switzerland) 2025 Oct 8;30(19)
Molecules (Basel, Switzerland) 2025 Oct 8;30(19)
Uncovering the Regulatory Role of Proteins in EBSS-Induced Autophagy Using RNA-Seq Analysis.
Ruan C, Li Y, Wu R
Biology 2025 Oct 8;14(10)
Biology 2025 Oct 8;14(10)
Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma.
Ding Y, Luo J, Deng YJ, Liu JL, Wang MQ, Hu Y
Journal of thoracic disease 2025 Oct 31;17(10):7810-7825
Journal of thoracic disease 2025 Oct 31;17(10):7810-7825
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
Li H, Ouyang J, Zhang Y, Zhang Z, Sun M, Liu R, Qian C
Scientific reports 2025 Oct 29;15(1):37897
Scientific reports 2025 Oct 29;15(1):37897
Bisphenol A Disrupts Spermatogenesis via Excessive Mitophagy-Driven Ferroptosis.
Zhou Y, Duan H, Wang X, Sheng X, Qi X, Liu B, Chen X, Fang Z, Dong W, Xiao L
Environmental science & technology 2025 Oct 28;59(42):22423-22438
Environmental science & technology 2025 Oct 28;59(42):22423-22438
The WW domain presents a promising target for the development of PCIF1 agonists in the treatment of glioma.
Yin J, Liu G, Zhou Y, Zhou J, Guo M, Hu Z, Musunuru PP, Yu R, Meng Q, Gao S
NPJ precision oncology 2025 Oct 23;9(1):329
NPJ precision oncology 2025 Oct 23;9(1):329
Inhibition of glutamine synthetase enhances hepatocellular carcinoma radiosensitivity through ROS-induced excessive mitophagy.
Liu R, Ju G, Lu Y, Liu X, Ding Q, Wang K, Gu H, Qian J
Molecular biology reports 2025 Oct 23;53(1):5
Molecular biology reports 2025 Oct 23;53(1):5
Lipidomics Revealed the Suppression of 5-PAHSA from Human Milk on Macrophage Foam Cell Formation.
Zhang Y, Zhu S, He Y, Lei JN, Wang H, Tan C, Liu YF, Chen M, Xu YJ
Journal of agricultural and food chemistry 2025 Oct 22;73(42):27089-27098
Journal of agricultural and food chemistry 2025 Oct 22;73(42):27089-27098
HIF-1α Activates Mitophagy through BNIP3 to Inhibit IPEC-J2 Apoptosis under Heat Stress.
Li H, Bai X, Yang T, Wu C, Liu Y, Shan C, Lin R, Wen X, Cheng A
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26621-26632
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26621-26632
Curcumin's dual effect on pyroptosis and autophagy in metabolic- associated fatty liver disease: a potential therapeutic strategy.
Eldken ZH, Youssef OM, Khalil RM, Kassab AAM, Ramadan A, Sakr NH
Scientific reports 2025 Oct 2;15(1):34309
Scientific reports 2025 Oct 2;15(1):34309
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Li X, Li J, Gou F, Dai Y, Zhao M, Wang D, Sun Z, Wen P, Wang J, Fan Q, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123860
Life sciences 2025 Oct 15;379:123860
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
Fang L, Lyu L, Zhong H, Lin J, Ren P, Wang Y, Yin Y, Zhang M, Qu Y
European journal of pharmacology 2025 Oct 15;1005:178043
European journal of pharmacology 2025 Oct 15;1005:178043
CORM-3 mitigates osteoarthritis by anti-inflammation and enhancing autophagy via inhibiting MAPK and mTOR pathways.
Li J, Zeng Y, Wang S, Chen X, Huang H, Gan X, Kang H
International immunopharmacology 2025 Oct 10;163:115296
International immunopharmacology 2025 Oct 10;163:115296
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Sun W, Sheng X, Li R, Li P, Lin H, Gong Y
International immunopharmacology 2025 Oct 10;163:115251
International immunopharmacology 2025 Oct 10;163:115251
Inhibition of DYRK1A can alleviate MPTP/MPP(+)-induced neuronal apoptosis and mitochondrial damage.
Cai Q, Xia H, Li P, Yao Y, Luo Q, Yang X
Brain research bulletin 2025 Oct 1;230:111516
Brain research bulletin 2025 Oct 1;230:111516
Development of an efficient mice model of cancer-associated cardiac cachexia.
Xiong S, Zheng H, Wu T, Tan J, Huang T, Shen C, Ji Y, Liu M, Wan J, Cai W
Animal models and experimental medicine 2025 Nov;8(11):1960-1970
Animal models and experimental medicine 2025 Nov;8(11):1960-1970
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Zou Y, Mao Z, Xu J, Wang W, Wang Z, Dai J, Zheng R, Du M, Zhang Z
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues.
Hua H, Cheng F, Meng Z, Zhang A, Li M, Zhang M, Lou P, Zhu Y, Tong P, Zhang Y
Journal of orthopaedic translation 2025 Nov;55:293-308
Journal of orthopaedic translation 2025 Nov;55:293-308
Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathway.
Liu S, Wu J, Lin Y, Liang H, Cai Y, Wang L, Wang Z, Sang H
Journal of orthopaedic translation 2025 Nov;55:146-158
Journal of orthopaedic translation 2025 Nov;55:146-158
Cadmium-mediated autophagy increases ferroptosis of ovarian granulosa cells.
Yang L, Xu Y, Gao Y, Wan X, Chen N
Toxicology 2025 Nov;517:154224
Toxicology 2025 Nov;517:154224
NFE2L2 protects against Sorafenib-induced Ferroptosis and cardiotoxicity by activating the HO1/ferritin pathway.
Jiang H, Su Y, Hou Y, Wang C
Toxicology and applied pharmacology 2025 Nov;504:117537
Toxicology and applied pharmacology 2025 Nov;504:117537
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
Zhao R, Wang Z, Liu C, Zhang L, Zhang M, Du H, Yang G, Sun H, Liu W, Yan S, Wang M
Journal of ginseng research 2025 Nov;49(6):652-662
Journal of ginseng research 2025 Nov;49(6):652-662
A novel GM-CSF-encoding oncolytic adenovirus induces profound autophagy and promotes viral replication to enhance anti-tumor efficacy.
Cao H, Ye J, Li X, Si Y, Jin X, Xiong S, Ji T, Ding Y, Ma D, Gao Q, Wang X, Dai Z, Li F
Cancer gene therapy 2025 Nov;32(11):1276-1291
Cancer gene therapy 2025 Nov;32(11):1276-1291
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
Gong B, Li F, Bai Y, Guo Y, Zhang R, Yu Y, Dong B
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
Xia F, Li W, Wang W, Liu J, Li X, Cai J, Shan H, Cai Z, Cui J
Autophagy 2025 Nov;21(11):2422-2442
Autophagy 2025 Nov;21(11):2422-2442
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Guo J, Wu B, Wang S, Huang D, Hu Y
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
Qin X, Liu J, Zhao X, Wang L, Liu X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
CERKL Reduced PI3P/Autophagy to Promote Pancreatic Cancer.
Zeng W, Yang Y, Li W, Pan J, Huang B, Zhang P, Xiao J
Cancer medicine 2025 Nov;14(22):e71402
Cancer medicine 2025 Nov;14(22):e71402
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
Wang J, Zha F, Lin S, Wei Y, Xuan L, Ye Z, Huang H
Journal of dermatological science 2025 Nov;120(2):61-70
Journal of dermatological science 2025 Nov;120(2):61-70
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Wu Y, Liu H, Wang Q, Zhang T, Chen R, Yuan Q, Tong X, Yang W, Xiao Y, Yan F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane.
Liu PH, Lin YS, Chu WH, Sun WT, Huang PY, Huang JR, Chiang WC
Biology direct 2025 Nov 6;20(1):108
Biology direct 2025 Nov 6;20(1):108
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
Yan W, Li H, Yu X, Chen X, Ma L, Deng X, Zhang J
Food chemistry 2025 Nov 30;493(Pt 2):145797
Food chemistry 2025 Nov 30;493(Pt 2):145797
TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy.
Yang J, Dong Y, Xu J, Qian X, Cai Y, Chen Y, Zhang P, Gao D, Cui Z, Cui Y
Developmental cell 2025 Nov 3;60(21):2862-2879.e8
Developmental cell 2025 Nov 3;60(21):2862-2879.e8
Oxymatrine Alleviates Cerebral Ischemia/Reperfusion Injury By Targeting HDAC1 to Regulate Mitochondria-Related Autophagy and Oxidative Stress.
Ma CS, Han B, Liu YX, Shi CK, Li DL, Guo JF, Bai M, Meng SC, Zhang LY, Duan MY, He MT
Molecular neurobiology 2025 Nov 29;63(1):219
Molecular neurobiology 2025 Nov 29;63(1):219
Ferroptosis mediated by ferritinophagy is involved in liver injury caused by sepsis.
Zhang H, Li H, Liu S, Zheng J, Li P
Scientific reports 2025 Nov 27;15(1):45489
Scientific reports 2025 Nov 27;15(1):45489
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Liang X, Xu J, Shu S, Lv W, Yin D, Miao S, Lu X, Zhang C, Liu X, Dai J, Li J, Wu W, Zhang E, Guo R
NPJ precision oncology 2025 Nov 26;9(1):391
NPJ precision oncology 2025 Nov 26;9(1):391
Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression.
Pan Y, Zhang N, Fu X, Wang X, Ma Y, Chen Q, Zhou Y, Liu H, Zhu Y, Xu L, Wang Q, Chen D, Wang Z, Wang L
Journal of experimental & clinical cancer research : CR 2025 Nov 25;44(1):310
Journal of experimental & clinical cancer research : CR 2025 Nov 25;44(1):310
Matrine activates high xenophagy to inhibit enterovirus replication.
Li X, Liu Y, Yu X, Guan X, Liu S, Huo W, Zhou X, Cui M, Liu M, Wang C, Huang C, Bai H, Yin S, Bai S, Yu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157522
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157522
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Zheng D, Shu J, Gao B, Yu H, Liu K, Zheng M, Liu X, Chen G, Lin Y, Li Q, Sun Y, Zheng Y, Li B, Yang X, Wang K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Semen Ziziphi Spinosae affects circadian rhythm of the cAMP signaling pathway by BMAL1-clockophagy to improve sleep disorders in depression.
Zhang Y, Feng Y, Lu Y, Ying Y, Wang D, Ying X, Pang Z, Zhang W, Liu Z, Zheng W, Yang F, Xu Q, Chen S, Zhu Y, Yu J, Zhu Z, Sun H, He S, Zhang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157483
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157483
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Xu Z, Si J, Liang A, Zhang Y, Gong J, Li G, Zhong Y, Yu M, Feng R, Li X, Chang J, Wang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Glaucocalyxin A induces autophagy-mediated ferroptosis by targeting PRDX1 and TXNRD1 proteins in non-small cell lung cancer.
Wang Y, Luo W, Shen S, Zhuang Y, Zhu Y, Liu Y, Zhang J, Meng Y, Pan L, Luo T, Xia F, Liu Y, Li S, Shen S, Liu Q, Wang J, Gu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157280
[Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway].
Yi M, Luo Y, Wu L, Wu Z, Jiang C, Chen S, Ke X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2427-2437
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2427-2437
Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.
Zhang Y, Fan T
Antioxidants (Basel, Switzerland) 2025 Nov 19;14(11)
Antioxidants (Basel, Switzerland) 2025 Nov 19;14(11)
Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis.
Zhao Y, Wang Y, Huang K, Wang F, Wang Y
Virology journal 2025 Nov 17;22(1):379
Virology journal 2025 Nov 17;22(1):379
GLP-1/GIP dual agonist tirzepatide alleviates mice model of Parkinson's disease by promoting mitochondrial homeostasis.
Tian R, Liu K, Lai H, Liao C, Li J, Tu H
International immunopharmacology 2025 Nov 14;165:115443
International immunopharmacology 2025 Nov 14;165:115443
AICAr Inhibition of cardiomyocyte autophagy promotes p62-dependent NRF2 expression and protection against doxorubicin toxicity.
Fassett EK, Mayer B, Fassett JT
Cellular and molecular life sciences : CMLS 2025 Nov 13;82(1):395
Cellular and molecular life sciences : CMLS 2025 Nov 13;82(1):395
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway.
Li J, Li J, Xie T, Huang S, Tian H, Liu M, Kong X, Zhang D, Nawaz KI, Wang M, Li H, Zhang J, Yuan F, Guo W, Cui X, Mu H, Hu Y
Cell communication and signaling : CCS 2025 Nov 12;23(1):492
Cell communication and signaling : CCS 2025 Nov 12;23(1):492
An effector of phosphatidylinositol 3-kinase activity promotes Rickettsia rickettsii virulence by enhancing autophagy.
Huang D, OuYang X, Peng Z, Chen D, Song L, Luo Z-Q
mBio 2025 Nov 12;16(11):e0228425
mBio 2025 Nov 12;16(11):e0228425
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Huang T, Tang Y, Su Q, Su C, Wang J, Fu L, Tang Y
Cell death & disease 2025 Nov 10;16(1):815
Cell death & disease 2025 Nov 10;16(1):815
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Kan X, Xu P, Yu M, Guo W, Cao Y, Hu G, Liu J, Fu S, Bi J
Scientific reports 2025 Nov 10;15(1):39252
Scientific reports 2025 Nov 10;15(1):39252
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Huang HJ, Lin YC, Ho LJ, Su RY, Liu WC, Chiu HW
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis.
Xiang X, Huang L, Luo W, Qin L, Bian M, Chen W, Han G, Wang N, Mo G, Zhang C, Zhang Y, Yang H, Lu S, Zhang J, Fu T
Journal of orthopaedic translation 2025 May;52:249-264
Journal of orthopaedic translation 2025 May;52:249-264
S-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy.
Zheng W, Pu M, Zeng S, Zhang H, Wang Q, Chen T, Zhou T, Chang C, Neculai D, Liu W
The EMBO journal 2025 May;44(9):2596-2619
The EMBO journal 2025 May;44(9):2596-2619
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
Al-Maamari A, Sultan M, Wu S, Zhang T, Wang C, Han B, Duan Y, Ding SS, Chen N, Zhang H, Sun F, Chen X, Yu D, Su S
International journal of biological macromolecules 2025 May;310(Pt 4):143549
International journal of biological macromolecules 2025 May;310(Pt 4):143549
Acetylation of Hsc70 at K512 inhibits goat ovarian granulosa cell senescence by restoring chaperone-mediated autophagy.
Li Y, Wang Y, Yao H, Li Z, Wang L, Song S, Li J, Li Y, Yang M, Zhang K, Han Y, Zhao Y, Yao S, Li Q, Ma Z, Xu D, Zhao Z
International journal of biological macromolecules 2025 May;310(Pt 2):143119
International journal of biological macromolecules 2025 May;310(Pt 2):143119
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Zhang L, Wu G, Yao J, Wang D, Gao F, Qian Z
International journal of biological macromolecules 2025 May;309(Pt 4):143143
International journal of biological macromolecules 2025 May;309(Pt 4):143143
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
Wang M, Wang Y, Wang X, Qiu Y, Li C, Li H, Li H, Yu J
International journal of biological macromolecules 2025 May;309(Pt 4):143033
International journal of biological macromolecules 2025 May;309(Pt 4):143033
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Cai Y, Xu H, Deng K, Yang H, Zhao B, Zhang C, Li S, Wei Z, Wang Z, Wang F, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 1):141271
International journal of biological macromolecules 2025 May;306(Pt 1):141271
Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis.
Bao Z, Xu M, Kan Y, Guo X, Li M, Wang J, Zhou Y, Zhang Z, Shao J, Zhang F, Chen L, Zheng S, Xuan J
International journal of biological macromolecules 2025 May;305(Pt 1):141055
International journal of biological macromolecules 2025 May;305(Pt 1):141055
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Guo C, Zhang T, Du L, Yu K, Zeng S, Li M, Chi Y, Li Y
Biochemical pharmacology 2025 May;235:116821
Biochemical pharmacology 2025 May;235:116821
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
Xin Y, Zhang Y, Yuan Z, Li S
Free radical biology & medicine 2025 May;232:28-39
Free radical biology & medicine 2025 May;232:28-39
Nicotine Ameliorates α-Synuclein Preformed Fibril-Induced Behavioral Deficits and Pathological Features in Mice.
Huang Z, Pan Y, Ma K, Luo H, Zong Q, Wu Z, Zhu Z, Guan Y
Applied biochemistry and biotechnology 2025 May;197(5):3026-3047
Applied biochemistry and biotechnology 2025 May;197(5):3026-3047
7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death.
Yang H, Jiang B, Li W, Du G, Xu F, Zhang Y, Yang Y, Zhang S, Cao W, Li X, Zhang X, Ji T, Wang J
British journal of pharmacology 2025 May;182(10):2310-2331
British journal of pharmacology 2025 May;182(10):2310-2331
NAT10 inhibition alleviates astrocyte autophagy by impeding ac4C acetylation of Timp1 mRNA in ischemic stroke.
Yang L, Li X, Zhao Y, Chen H, Wang C, Wu A, Guo X, Huang Y, Wang Q, Hao L, Li X, Ji Y, Ban J, Wang G, Cao J, Pan Z
Acta pharmaceutica Sinica. B 2025 May;15(5):2575-2592
Acta pharmaceutica Sinica. B 2025 May;15(5):2575-2592
Liensinine overcomes EGFR-TKI resistance in lung adenocarcinoma through DRP1-mediated autophagy.
Chen Y, Shu C, Yan Z, Zhang S, Zhang W, Zhao J, Wang A, Li J, Zeng Y, Zhu J, Huang JA, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156593
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156593
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
Lin Y, Zhang J, Gao X, Wu Z, Yang L, Tian K, Lv X, Li J, Chen K, Zhang Y, Hu H, Zhu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
LAMP3 exacerbates autophagy-mediated neuronal damage through NF-kB in microglia.
Jia K, Shen R, Li Y, Shi W, Xia W
Cellular signalling 2025 May;129:111658
Cellular signalling 2025 May;129:111658
Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low-Temperature Photothermal Therapy via Targeting HSP90-TXNDC9 Interactions.
He D, Chen S, Wang X, Wen X, Gong C, Liu L, He G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2412953
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2412953
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
Luo A, Wang R, Gong J, Wang S, Yun C, Chen Z, Jiang Y, Liu X, Dai H, Liu H, Zheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Wang JQ, Liu XM, Zhu ZS, Li Z, Xie CZ, Qiao X, Feng YK, Xu JY
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Rab GTPases are evolutionarily conserved signals mediating selective autophagy.
Zhao P, Tian R, Song D, Zhu Q, Ding X, Zhang J, Cao B, Zhang M, Xu Y, Fang J, Tan J, Yi C, Xia H, Liu W, Zou W, Sun Q
The Journal of cell biology 2025 May 5;224(5)
The Journal of cell biology 2025 May 5;224(5)
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Jiang S, Bu S, Kang X, Dong Y, Chen L, Yuan L, Shi M, Du M, Liang M, Huang K, Yang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
Bai J, He S, Wang X, Zhang L, Ma C, Gao D, Yuan H, Mei J, Guan X, Yu H, Wan K, Zhu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
αSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis.
Chen Y, Sun LV
Scientific reports 2025 May 30;15(1):18989
Scientific reports 2025 May 30;15(1):18989
Calpain1 inhibition enhances autophagy-lysosomal pathway and ameliorates tubulointerstitial fibrosis in Nephronophthisis.
Li D, Zhang J, Su X, Yang Y, Lai J, Wei X, Chen H, Liu Y, Wang H, Sun L
Molecular medicine (Cambridge, Mass.) 2025 May 3;31(1):166
Molecular medicine (Cambridge, Mass.) 2025 May 3;31(1):166
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Xu Q, Lin R, Jiang T, Deng L, Wu Y, Yuan Q, Qi X, Mu P, Jiang J, Deng Y, Wen J
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Dihydroartemisinin alleviates diethylnitrosamine-induced hepatocarcinogenesis by targeting a novel MAZ/TRIM50 axis.
Liu R, Huang Y, Li D, Cui H, Tang Y, Hu Y, Xu L, Lin C, Qi G, Chen L, Zhang Z, Tan S, Zhu X
International immunopharmacology 2025 May 27;156:114733
International immunopharmacology 2025 May 27;156:114733
RAB18 deficiency disrupts lipid metabolism and autophagy in mice.
Zhang LW, Han YQ, Yang Y, Li YJ, Ma YX, Ming SL
Biochemical and biophysical research communications 2025 May 26;760:151673
Biochemical and biophysical research communications 2025 May 26;760:151673
Long non-coding RNA HOXA11-AS inhibits apoptosis, induces proliferation, and promotes autophagy via the miR-214-3p/ATG12 axis in acute T lymphoblastic leukemia.
Zhang R, Zhang Y, Li X, Wang S, Li J, Shao S, Liu B, Guo W, Shi M
Journal of molecular histology 2025 May 26;56(3):170
Journal of molecular histology 2025 May 26;56(3):170
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.
Gong B, Liu Y, Yan W, Cheng C, Yang H, Huang J, Liu Q, Liu Y, Guo J, Deng X, Zhou B, Zheng D, Liu X, Liu Z, Fang W
Molecular cancer 2025 May 26;24(1):152
Molecular cancer 2025 May 26;24(1):152
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Zhang R, Cui Y, Pan Y, Wang M, Yu S, Xu R, Ma W, Wang J, Zhong D, Jiao Z
Biomolecules 2025 May 24;15(6)
Biomolecules 2025 May 24;15(6)
Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease.
Xia L, Li J, Pang Y, Dai C, Xu M, Du Y, Tian Q, Yi L, Wu B, Chen M, Qiu Y, Cheng C, Wang YT, Song W, Dong Z
Science advances 2025 May 23;11(21):eadt7981
Science advances 2025 May 23;11(21):eadt7981
SRSF1-mediated alternative splicing regulates bladder cancer progression and cisplatin sensitivity through HIF1A/BNIP3/mitophagy axis.
Wu Q, Yu H, Sun H, Lv J, Zhuang J, Cai L, Jiang L, Chen Y, Tao Y, Bai K, Yang H, Yang X, Lu Q
Journal of translational medicine 2025 May 22;23(1):571
Journal of translational medicine 2025 May 22;23(1):571
Autophagy and exosome dynamics in Radiation-Induced pulmonary fibrosis: the critical role of TRIB3.
Li N, Zhao W, Li J, Zhang D, Li K, Yang M, Lu X, Du L, Xu C, Liu Q
Respiratory research 2025 May 21;26(1):194
Respiratory research 2025 May 21;26(1):194
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.
Scialò C, Zhong W, Jagannath S, Wilkins O, Caredio D, Hruska-Plochan M, Lurati F, Peter M, De Cecco E, Celauro L, Aguzzi A, Legname G, Fratta P, Polymenidou M
Neuron 2025 May 21;113(10):1614-1628.e11
Neuron 2025 May 21;113(10):1614-1628.e11
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
Zhang X, Deng Z, Zhang X, Xu Q, Liu L, Yang D, Guo Z
European journal of medical research 2025 May 20;30(1):403
European journal of medical research 2025 May 20;30(1):403
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Gao L, Liu J, Li Y, Yang J, Cai J, Wang L, Ye Z, Tong S, Deng G, Chen Q, Cai Q
Scientific reports 2025 May 20;15(1):17488
Scientific reports 2025 May 20;15(1):17488
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Wang S, Du T, Yan J, Zheng Y, Tang Y, Wu J, Xu Q, Xu S, Liu L, Chen X, Han S, Yin J, Peng B, He X, Liu W
Retrovirology 2025 May 2;22(1):7
Retrovirology 2025 May 2;22(1):7
Effects of Aerobic Exercise on Irisin and Skeletal Muscle Autophagy in ApoE(-/-) Mice.
Wang W, Zheng F, Zhou J, Cao Y, Zhang L, Lu Y, Li Q, Li T, Korivi M, Wang L, Li W
Current issues in molecular biology 2025 May 19;47(5)
Current issues in molecular biology 2025 May 19;47(5)
Lysionotin promoted apoptosis of hepatocellular carcinoma cells via inducing autophagy.
Wang X, Zhong W, Wang Q, Song P, Lin X, Li B, Yin Y, Yang C, Li M
Discover oncology 2025 May 16;16(1):788
Discover oncology 2025 May 16;16(1):788
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
Shen R, Xia P, Guo Y, Ji P, Yuan X, Wang L, Shuang S, Zhou L, Tong R, Zhang L, Liu D, Wang D
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C
Bone research 2025 May 12;13(1):51
Bone research 2025 May 12;13(1):51
Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.
Zhang R, Liang L, Liao K, Zeng H, Yang X, Wang X, Wang B, Yuan J
Investigative ophthalmology & visual science 2025 May 1;66(5):23
Investigative ophthalmology & visual science 2025 May 1;66(5):23
Mechanism of arsenic regulation of mitochondrial damage and autophagy induced synaptic damage through SIRT1 and protective effect of melatonin in HT22 cell.
Zhang X, Wang J, Li S, Chen K, Wang L, Feng C, Gao Y, Yan X, Zhao Q, Li B, Zheng J, Qiu Y
Chemico-biological interactions 2025 May 1;412:111461
Chemico-biological interactions 2025 May 1;412:111461
Analysis of the key signaling pathway of baicalin that induces autophagy in papillary thyroid cancer via an optical resonator.
Lai Y, Ru D, Ding C, Wang C, Ding L, Luo C, Qi Y, Chen X, Dai H, Li H
Biomedical optics express 2025 May 1;16(5):1843-1855
Biomedical optics express 2025 May 1;16(5):1843-1855
Hsp90 and HIF-1α regulate mitophagy by promoting BNIP3 expression in renal ischemia-reperfusion injury.
Dong Q, Li X, Cheng K
Transplant immunology 2025 Mar;89:102177
Transplant immunology 2025 Mar;89:102177
Caloric restriction exacerbates renal post-ischemic injury and fibrosis by modulating mTORC1 signaling and autophagy.
Shi L, Zha H, Zhao J, An H, Huang H, Xia Y, Yan Z, Song Z, Zhu J
Redox biology 2025 Mar;80:103500
Redox biology 2025 Mar;80:103500
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation.
Duan Q, Wang W, Xiong H, Xiao J, Xiao H, Zhu F, Lu H
Oncogene 2025 Mar;44(9):587-600
Oncogene 2025 Mar;44(9):587-600
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
NLRX1 deficiency exacerbates skin inflammation in atopic dermatitis by disrupting mitophagy.
Yue L, Qiao P, Li X, Xue K, Pang B, Bai Y, Song P, Qu H, Qiao H, Sun D, Wu X, Liu R, Wang G, Dang E
Clinical immunology (Orlando, Fla.) 2025 Mar;272:110442
Clinical immunology (Orlando, Fla.) 2025 Mar;272:110442
Rpl12 is a conserved ribophagy receptor.
Chen Y, Hu J, Zhao P, Fang J, Kuang Y, Liu Z, Dong S, Yao W, Ding Y, Wang X, Pan Y, Wu J, Zhao J, Yang J, Xu Z, Liu X, Zhang Y, Wu C, Zhang L, Fan M, Feng S, Hong Z, Yan Z, Xia H, Tang K, Yang B, Liu W, Sun Q, Mei K, Zou W, Huang Y, Feng D, Yi C
Nature cell biology 2025 Mar;27(3):477-492
Nature cell biology 2025 Mar;27(3):477-492
Bisdemethoxycurcumin mitigates traumatic brain injury in rats by modulating autophagy and oxidative stress via heat shock protein 90 alpha family class A member 1-mediated nuclear translocation of transcription factor EB.
Xu Y, Peng LS, Xiao CQ, Zhou Y, Wang QS, Fu H
Brain research bulletin 2025 Mar;222:111221
Brain research bulletin 2025 Mar;222:111221
Dehydroervatamine as a promising novel TREM2 agonist, attenuates neuroinflammation.
Li L, Xu N, He Y, Tang M, Yang B, Du J, Chen L, Mao X, Song B, Hua Z, Tang B, Lee SM
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Mar;22(2):e00479
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Mar;22(2):e00479
USP13 facilitates a ferroptosis-to-autophagy switch by activation of the NFE2L2/NRF2-SQSTM1/p62-KEAP1 axis dependent on the KRAS signaling pathway.
Chen L, Ning J, Linghu L, Tang J, Liu N, Long Y, Sun J, Lv C, Shi Y, Tao T, Xiao D, Cao Y, Wang X, Liu S, Li G, Zhang B, Tao Y
Autophagy 2025 Mar;21(3):565-582
Autophagy 2025 Mar;21(3):565-582
ATP6V1D drives hepatocellular carcinoma stemness and progression via both lysosome acidification-dependent and -independent mechanisms.
Xu Z, Liu R, Ke H, Xu F, Yang P, Zhang W, Zhan Y, Zhao Z, Xiao F
Autophagy 2025 Mar;21(3):513-529
Autophagy 2025 Mar;21(3):513-529
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
Li O, An K, Wang H, Li X, Wang Y, Huang L, Du Y, Qin N, Dong J, Wei J, Sun R, Shi Y, Guo Y, Sun X, Yang Y, Yang YG, Kan Q, Tian X
Clinical and translational medicine 2025 Mar;15(3):e70270
Clinical and translational medicine 2025 Mar;15(3):e70270
2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione mediates the effect of ROS-enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer.
Chen L, Chen M, Xie Y, Zhang Y, Mo S, He Y, Liang T, Liao Y, Huang R, Huang G, Han C, Pham TTH
FEBS open bio 2025 Mar;15(3):474-489
FEBS open bio 2025 Mar;15(3):474-489
SIRT5-mediated GLS and GDH desuccinylation attenuates the autophagy of bovine mammary epithelial cells induced by ammonia.
Yang H, Gao S, Lu G, He J, Dong J, Zhang X, Liu L, Zhong K, Zha G, Han L, Guo S, Li H, Wang Y
Cellular signalling 2025 Mar;127:111570
Cellular signalling 2025 Mar;127:111570
TFE3-mediated neuroprotection: Clearance of aggregated α-synuclein and accumulated mitochondria in the AAV-α-synuclein model of Parkinson's disease.
He X, Chen M, Fan Y, Wu B, Dong Z
Genes & diseases 2025 Mar;12(2):101429
Genes & diseases 2025 Mar;12(2):101429
Microglia-Derived Interleukin-6 Triggers Astrocyte Apoptosis in the Hippocampus and Mediates Depression-Like Behavior.
Shen SY, Liang LF, Shi TL, Shen ZQ, Yin SY, Zhang JR, Li W, Mi WL, Wang YQ, Zhang YQ, Yu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2412556
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2412556
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Shi M, Li X, Guo Y, Zhang Y, Xu J, Yan L, Liu R, Wang H, Tang S, Zhao Y, Li Z, Feng Y, Ren D, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
Yang H, Wang Y, Liu S, Zhang S, Chen Y, Ding J, Chen S, Zhu F, Xia B, Luo P, Liu Y
Neurotoxicology 2025 Mar;107:53-61
Neurotoxicology 2025 Mar;107:53-61
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Zhang S, Gu M, Yin H, Pan S, Xie H, Chen W, Gul S, Zhao Y, Wang Z, Zheng W, You Y, You B
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Costunolide Ameliorates the Methylmalonic Acidemia Via the PINK1/Parkin Pathway.
Lu X, Zheng H, Bai H, Wang Y, Li L, Ma B
Neurochemical research 2025 Mar 7;50(2):115
Neurochemical research 2025 Mar 7;50(2):115
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
Qi H, Gao H, Li M, Sun T, Gu X, Wei L, Zhi M, Li Z, Fu D, Liu Y, Wei Z, Dou Y, Feng Q
Nature communications 2025 Mar 7;16(1):2305
Nature communications 2025 Mar 7;16(1):2305
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Peng X, Yang R, Wang C, Peng W, Zhao Z, Shi S, Cai Q, He B, Wang L, Yu F, Wang X, Tao Y
Cancer letters 2025 Mar 31;613:217503
Cancer letters 2025 Mar 31;613:217503
Poria cocos-Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation.
Wang T, Zhao J, Li QY, Yang HQ, Li M, Duan R, Zhang M, Qi Y, Yu J, Yang XX
International journal of molecular sciences 2025 Mar 3;26(5)
International journal of molecular sciences 2025 Mar 3;26(5)
Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy.
Xia B, Liang J, Lu Y, Ding J, Peng J, Li F, Dai J, Liu Y, Wang J, Wan C, Luo P
Scientific reports 2025 Mar 27;15(1):10585
Scientific reports 2025 Mar 27;15(1):10585
Regulation on mitophagy in adenomyosis by Guizhi Fuling Wan.
Liu S, Li C, Fu X, Chen M, Wang M, Wang K, Du L
Journal of ethnopharmacology 2025 Mar 26;344:119570
Journal of ethnopharmacology 2025 Mar 26;344:119570
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
Xu Y, Liang H, Xia K, Yao J, Chen Y, Hou B, Hao Z
International immunopharmacology 2025 Mar 26;150:114250
International immunopharmacology 2025 Mar 26;150:114250
DKS26 Alleviates Ischemia-Reperfusion Injury-Induced Acute Kidney Injury by Stabilizing Vitamin D Receptors to Inhibit the Inflammatory Pathway of NF-κB P65.
Liang L, Ruan Y, Yu X, Tan W, Xu X, Jia J, Peng J, Wang F, Peng Y, Chen Y, Liu L, Guo B, Zhang J, Wang Y
International journal of molecular sciences 2025 Mar 25;26(7)
International journal of molecular sciences 2025 Mar 25;26(7)
Rapamycin mitigates neurotoxicity of fluoride and aluminum by activating autophagy through the AMPK/mTOR/ULK1 pathway in hippocampal neurons and NG108-15 cells.
Tao D, Xia Y, Liao Q, Yang X, Zhang L, Xie C
Scientific reports 2025 Mar 21;15(1):9801
Scientific reports 2025 Mar 21;15(1):9801
FBXO45 restricts HIV-1 replication by inducing SQSTM1/p62-mediated autophagic degradation of Tat.
Xu M, Hu H, Yang W, Zhang J, Wang H, Zhang W, Huan C
Journal of virology 2025 Mar 18;99(3):e0191224
Journal of virology 2025 Mar 18;99(3):e0191224
Exploring the effect of chlorogenic acid on oxidative stress and autophagy in dry eye mice via the AMPK/ULK1 pathway.
Chen H, Shi J, Tang Y, Chen X, Wang Z, Liu Q, Wu K, Yao X
European journal of pharmacology 2025 Mar 15;991:177311
European journal of pharmacology 2025 Mar 15;991:177311
Lysophosphatidylcholine promoting α-Synuclein aggregation in Parkinson's disease: disrupting GCase glycosylation and lysosomal α-Synuclein degradation.
Mu C, Shao K, Su M, Guo Y, Qiu Y, Sun R, Sun S, Sun Y, Liu C, Wang W, Qin X, Tang C
NPJ Parkinson's disease 2025 Mar 15;11(1):47
NPJ Parkinson's disease 2025 Mar 15;11(1):47
HTLV-1 Tax induces PINK1-Parkin-dependent mitophagy to mitigate activation of the cGAS-STING pathway.
Mohanty S, Suklabaidya S, Mnatsakanyan N, Jacobson S, Harhaj EW
bioRxiv : the preprint server for biology 2025 Mar 15;
bioRxiv : the preprint server for biology 2025 Mar 15;
Characterization and neurotherapeutic evaluation of venom polypeptides identified from Vespa magnifica: The role of Mastoparan-M in Parkinson's disease intervention.
Liu C, Li X, Chen M, Liu Y, Li K, Wang D, Yang Z, Guo Y, Zhao Y, Zhao H, Zhang C
Journal of ethnopharmacology 2025 Mar 13;343:119481
Journal of ethnopharmacology 2025 Mar 13;343:119481
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation.
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Shimada T, Niiyama S, Sasazawa Y, Ishikawa K, Akamatsu W, Hattori N
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Mar 12;45(11)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Mar 12;45(11)
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Zhao N, Xu A, Yang J, Zhao J, Xie J, Li B, Duan J, Cao G
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation.
Guo D, Pang Y, Wang W, Feng Y, Wang L, Sun Y, Hao J, Li F, Zhao S
Cells 2025 Mar 1;14(5)
Cells 2025 Mar 1;14(5)
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Ou W, Li X, Tang K, Ding L, Sun T, Li Q, Li T
Science China. Life sciences 2025 Jun;68(6):1689-1702
Science China. Life sciences 2025 Jun;68(6):1689-1702
HN1 Functions in Protein Synthesis Regulation via mTOR-RPS6 Axis and Maintains Nucleolar Integrity.
Özduman G, Javed A, Akçaöz Alasar A, Akgül B, Korkmaz KS
Cell proliferation 2025 Jun;58(6):e13805
Cell proliferation 2025 Jun;58(6):e13805
Accumulation of microtubule-associated protein tau promotes hepatocellular carcinogenesis through inhibiting autophagosome-lysosome fusion.
Liu X, Hao Z, He H, Wang X, Wang W, Shu X, Sun B, Hu Z, Hu S, Hou X, Xiao Y, Zhou H, Liu Y, Wang J, Fu Z
Molecular and cellular biochemistry 2025 Jun;480(6):3621-3635
Molecular and cellular biochemistry 2025 Jun;480(6):3621-3635
SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression.
Zhang L, Wang X, Hu D, Li S, Sun M, Liu Q, Feng H, Zhou M, Chen C, Zhou H, Ma S
Oncogene 2025 Jun;44(23):1844-1855
Oncogene 2025 Jun;44(23):1844-1855
Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Segura-Roman A, Citron YR, Shin M, Sindoni N, Maya-Romero A, Rapp S, Goul C, Mancias JD, Zoncu R
The EMBO journal 2025 Jun;44(11):3150-3179
The EMBO journal 2025 Jun;44(11):3150-3179
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Wang A, Zhang F, Zhang W, Gong J, Sun X
Experimental neurology 2025 Jun;388:115218
Experimental neurology 2025 Jun;388:115218
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Li W, Yin Q, Qiu Y, Liu J, Wang J, Li C, Zhang D, Zhang P, Lv H, Lv Y, Wang Y
Cancer genetics 2025 Jun;294-295:156-170
Cancer genetics 2025 Jun;294-295:156-170
Reduced store operated calcium entry contributes to autophagy mediated escape of prostate cancer to oxaliplatin treatment.
Kannancheri Puthooru D, Yassine M, Gordienko D, Ziental-Gelus N, Desruelles E, Farfariello V, Lemonnier L, Prevarskaya N
Biochimica et biophysica acta. Molecular cell research 2025 Jun;1872(5):119953
Biochimica et biophysica acta. Molecular cell research 2025 Jun;1872(5):119953
Photobiomodulation regulates inflammation and autophagy in spinal cord injury through NLRP3/Caspase-1/IL-1β pathway by targeting TLR2.
Zuo X, Ju C, Zhang Z, Wei X, Ma Y, Song Z, Zhang J, Luo L, Zhu Z, Wang Z, Hu X
Molecular immunology 2025 Jun;182:1-10
Molecular immunology 2025 Jun;182:1-10
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Han J, Hong R, Cao C, Feng W, Zhuang W, Wang G, Tang J, Yang Y, Zhang C, Zhou A, Qu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Antitumor/anti-inflammatory effects/tissue healing as an all-in-one therapeutic strategy for nasopharyngeal carcinoma.
Ni F, Lv H, Lin L, Zhang Y, Qiao Y, Zhang X, Li Z, Wang X, Dai X, Dong J
Journal of nanobiotechnology 2025 Jun 9;23(1):431
Journal of nanobiotechnology 2025 Jun 9;23(1):431
Polypyrrole-ferric phosphate-methotrexate nanoparticles enhance apoptosis/ferroptosis of M1 macrophages via autophagy blockage for rheumatoid arthritis treatment.
Liu H, Wan H, Zhang A, Ouyang Y, Lu X, Wu M, Hu N, Pan J, Guo D, Li ZA, Xie D
Journal of nanobiotechnology 2025 Jun 7;23(1):428
Journal of nanobiotechnology 2025 Jun 7;23(1):428
β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1.
Li Y, Fang J, Ding Y, Zhang X, Liu Y, Qiu W, Xu H, Kang Y, Chen J, Gao Y, Zhao YG, Yang P, Wang B, Tian W, Chen Y, Bi W, Zhang P
Nature communications 2025 Jun 5;16(1):5227
Nature communications 2025 Jun 5;16(1):5227
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168
Journal of neuroinflammation 2025 Jun 28;22(1):168
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
Xiang D, Zhang X, Xue X, Liang H, Meng J, Zhao S, Yang J, Zhou Y, Hu Y, Xu L, Shi M, Zhang J, Wang M, Chen J, Han Y
Journal of ethnopharmacology 2025 Jun 26;350:120055
Journal of ethnopharmacology 2025 Jun 26;350:120055
Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets.
Feng Q, Yuan J, Hu Y, Feng C, Lin X, Liu S, Ji S, Mao X, Lin X, Cong J, Li X, Li X, Li H, Yan D, Dai J
Cell reports 2025 Jun 24;44(6):115771
Cell reports 2025 Jun 24;44(6):115771
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Zhang Y, Yang E, Zhang X, Zhang Z, Huang G, Tang B, Chen C, Lai L, Pei Z, Zhang Y, Wang Z
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
Li Y, Shang J, Zhang H, Lu Y, Zhao Y, Wang Y, Yan X, Zhang J
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Fan L, Xu F, Liu S, Wu D, Wang S, Pan X, Zhou Y, Qu L, Zhou W
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
Zhang F, Dong Y, Yang Z, Guo C, Zhang X, Shang Y, Li L, Gao M, Pang Y
International immunopharmacology 2025 Jun 17;158:114831
International immunopharmacology 2025 Jun 17;158:114831
Exposure of the human placental primary cells to nanoplastics induces cytotoxic effects, an inflammatory response and endocrine disruption.
Poinsignon L, Lefrère B, Ben Azzouz A, Chissey A, Colombel J, Djelidi R, Ferecatu I, Fournier T, Beaudeux JL, Lespes G, Zerrad-Saadi A
Journal of hazardous materials 2025 Jun 15;490:137713
Journal of hazardous materials 2025 Jun 15;490:137713
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Cheng Z, Gao H, Shi P, Zhang A, Chen X, Chen Y, Gan W, Zhao K, Li S, Yang C, Zhang Y
Bone research 2025 Jun 12;13(1):62
Bone research 2025 Jun 12;13(1):62
Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome.
Quan X, Yang Y, Liu X, Kaltwasser B, Pillath-Eilers M, Walkenfort B, Voortmann S, Mohamud Yusuf A, Hagemann N, Wang C, Hasenberg M, Hermann DM, Brockmeier U
Redox biology 2025 Jul;84:103700
Redox biology 2025 Jul;84:103700
Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4-regulated ferroptosis.
Wen SY, Gao RR, Chen YY, Wang YJ, Wang XT, Liu HX
Animal models and experimental medicine 2025 Jul;8(7):1155-1165
Animal models and experimental medicine 2025 Jul;8(7):1155-1165
ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.
Li X, Li W, Xie X, Fang T, Yang J, Shen Y, Wang Y, Wang H, Tao L, Zhang H
Molecular neurobiology 2025 Jul;62(7):9271-9289
Molecular neurobiology 2025 Jul;62(7):9271-9289
Adipose mesenchymal stem cell-derived extracellular vesicles regulate PINK1/parkin-mediated mitophagy to repair high glucose-induced dermal fibroblast senescence and promote wound healing in rats with diabetic foot ulcer.
Luo Y, Guo Q, Liu C, Zheng Y, Wang Y, Wang B
Acta diabetologica 2025 Jul;62(7):1041-1056
Acta diabetologica 2025 Jul;62(7):1041-1056
Inhibition of CDC27 O-GlcNAcylation coordinates the antitumor efficacy in multiple myeloma through the autophagy-lysosome pathway.
Wu HQ, Qin RC, Li WJ, Liu JN, Deng C, Zheng ZH, Zheng JP, Liu Y, Meng YF, Tang C, Tan HM, Duan FF, Tang Y, Xiao F, Lu LW, Dai XY, Ma KY
Acta pharmacologica Sinica 2025 Jul;46(7):2041-2055
Acta pharmacologica Sinica 2025 Jul;46(7):2041-2055
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
Huang H, Fang L, Zhu C, Lv J, Xu P, Chen Z, Zhang Z, Wang J, Wang W, Xu Z
Oncogene 2025 Jul;44(28):2357-2371
Oncogene 2025 Jul;44(28):2357-2371
Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway.
Zhao H, Wang W, Yang Y, Feng C, Lin T, Gong L
Ocular immunology and inflammation 2025 Jul;33(5):766-780
Ocular immunology and inflammation 2025 Jul;33(5):766-780
Metformin Improves Palmitate-Induced Follicular Granulosa Cell Dysfunction by Activating ULK1-Mediated Autophagy.
Heng N, Hao H, Hu Y, Wang Y, Wang H, He W, Zhu N, Wang R, Xuan X, Zhu H, Zhao S, Wang F
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jul;32(7):2442-2452
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jul;32(7):2442-2452
TRIM21-driven K63-linked ubiquitination of RBM38c, as a novel interactor of BECN1, contributes to DNA damage-induced autophagy.
Xia L, Xing Y, Ye X, Wu Y, Yang Y, Yin Z, Wang A, Chen J, Zhang M
Cell death and differentiation 2025 Jul;32(7):1317-1335
Cell death and differentiation 2025 Jul;32(7):1317-1335
Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy.
Wang H, Cheng G, Zhang S, Qu H, Zhao X, Yang A, Sun X, Pan H
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Extracellular GMFB activates the non-canonical FAS-FAF1 pathway to induce lysosomal dysfunction in early diabetic retinopathy.
Liu C, Gao F, Zhu L, Sun W, Zhu T, Shi S, Wang J, Ou Q, Xu JY, Li J, Xu J, Jia S, Bi Y, Jin C, Tian H, Xu GT, Lu L
International journal of biological macromolecules 2025 Jul;318(Pt 1):145082
International journal of biological macromolecules 2025 Jul;318(Pt 1):145082
Nuclear p62/SQSTM1 facilitates ubiquitin-independent proteasomal degradation of BMAL1.
Zhang C, Wu Q, Zhang H, Liu R, Li L
PLoS genetics 2025 Jul;21(7):e1011794
PLoS genetics 2025 Jul;21(7):e1011794
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma.
Shi H, Yang Y, Gao J, Kumar S, Xie H, Chen Z, Lyu J, Sihto H, Koljonen V, Vega-Rubin-de-Celis S, Vukojevic V, Farnebo F, Björnhagen V, Höög A, Juhlin CC, Lee L, Wickström M, Becker JC, Johnsen JI, Larsson C, Lui WO
Autophagy 2025 Jul;21(7):1523-1543
Autophagy 2025 Jul;21(7):1523-1543
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Tang Q, Tang K, Markby GR, Parys M, Phadwal K, MacRae VE, Corcoran BM
Autophagy 2025 Jul;21(7):1433-1455
Autophagy 2025 Jul;21(7):1433-1455
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Baicalein benefits amyotrophic lateral sclerosis via reduction of Intraneuronal misfolded protein.
Ting CH, Tai ST, Chang HY, Huang PY, Cheng LF, Lai HJ, Kuo YC, Kao CH, Wang IF, Tsai LK
Biochimica et biophysica acta. General subjects 2025 Jul;1869(8):130831
Biochimica et biophysica acta. General subjects 2025 Jul;1869(8):130831
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Li XJ, Huang KX, Wang KX, Liu R, Wang DC, Liang YR, Hao EJ, Wang Y, Guo HM
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
Jiang W, Fan X, Wu H, Song J, Yang C, Zhao Z
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
Ling L, Hu T, Zhou C, Dai Y, Hu L, Chen Y, Hu Z, Huang K, Chen J, Wang Y
Molecular cancer 2025 Jul 8;24(1):192
Molecular cancer 2025 Jul 8;24(1):192
Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane.
Chen T, Ouyang A, Zou J, Feng Y, Wu C, Jiang M, Tu S, Ding L, Cheng Y, Hu W, Sheng W, Li Y, Jin M, Chen H, Zhou H
Nature communications 2025 Jul 8;16(1):6271
Nature communications 2025 Jul 8;16(1):6271
hnRNPA2B1 restrains granulosa cell ferroptosis by m(6)A/SLC7A11 in premature ovarian failure.
Xiong J, He L, Zhang Y, Zhao X
Journal of ovarian research 2025 Jul 26;18(1):165
Journal of ovarian research 2025 Jul 26;18(1):165
Paeonol ameliorates diabetic nephropathy by promoting TFEB-mediated lysosome biogenesis and lipophagy.
Ai S, Tao J, Wang Y, Zhou J, Liu W, Li X, Wang L, Hou J, Zhao L, Wang Z, Peng L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156901
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156901
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Jia LL, Wu CJ, Ye PW, Zhang Q, Liu H, Li TP, Hu XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Chen X, Liu Q, Wu J, Zhou P, Zhao M, Song J
Nature communications 2025 Jul 23;16(1):6769
Nature communications 2025 Jul 23;16(1):6769
Interferon-stimulated gene MCL1 inhibits foot-and-mouth disease virus replication by modulating mitochondrial dynamics and autophagy.
Mogulothu A, Hickman D, Attreed S, Azzinaro P, Rodriguez-Calzada M, Dittmann M, de Los Santos T, Szczepanek S, Medina GN
Journal of virology 2025 Jul 22;99(7):e0058125
Journal of virology 2025 Jul 22;99(7):e0058125
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Dong X, Suo Y, Yu J, Yu F, Li F, Zheng J, Li G, Ma S, Hao Y, Zhang H, Liu B, Jiang Y
ACS nano 2025 Jul 22;19(28):25628-25644
ACS nano 2025 Jul 22;19(28):25628-25644
Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA.
Yang W, Li H, Wang S, Huang R, Zhang Y, Guo M, Huang L, Li S, Yang R, Zhao D, Xiong Y, Liu Y, Huang M, Hui L, Xiao W, Wu Y
Nature communications 2025 Jul 22;16(1):6756
Nature communications 2025 Jul 22;16(1):6756
Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma.
Li A, Gong Z, Long Y, Li Y, Liu C, Lu X, Li Q, He X, Lu H, Wu K, Nie Y, Tan J, Ye J, You H
Developmental cell 2025 Jul 21;60(14):1974-1990.e11
Developmental cell 2025 Jul 21;60(14):1974-1990.e11
Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death.
Zhang D, Song S, Lin J, Ye T, Yang X, Jiang Q, Mi Y, Zhang M, Ge X, Shen Y, Du P, Shi Y, Zhang X, Li L, Zhang Y, Ding L, Liu J, Zhang Y, Gao S, Ye Q
Developmental cell 2025 Jul 21;60(14):1958-1973.e9
Developmental cell 2025 Jul 21;60(14):1958-1973.e9
Uridine alleviates the aging of alveolar epithelial cells in idiopathic pulmonary fibrosis through the Keap1-Nrf2 signaling pathway.
Ding C, Zuo R, Liao Q, Guo Z, He J, Ye Z, Liu G
Scientific reports 2025 Jul 2;15(1):22952
Scientific reports 2025 Jul 2;15(1):22952
Kumatakenin alleviates depressive-like behaviors by suppressing excessive autophagy in hippocampus via ATG5.
Li L, Gu L, Hua Y, Xu H, Ling Y, Tong L, Chen M, Ma R
European journal of pharmacology 2025 Jul 15;999:177688
European journal of pharmacology 2025 Jul 15;999:177688
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Yuan C, Li C, Lu J, Liao S, Wu R, Li D, Huang M, Gong D, Wu W, Yu X, Fei S, Si W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
Genetic perturbation of cellular homeostasis regulates integrated stress response signaling to control Drosophila hematopoiesis.
Ghosh K, Iyer RK, Sood S, Islam MS, Labad JG, Khadilkar RJ
Biology open 2025 Jul 15;14(7)
Biology open 2025 Jul 15;14(7)
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Ji Y, Li R, Tang G, Xiao Y, Ye R, Shi J, Geng C, Ran R, Zhu C, Wang W, Chen C, Yang Q
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
Li Z, Liu F, Li F, Zeng G, Wen X, Ding J, Zhou J
Cell death & disease 2025 Jul 14;16(1):524
Cell death & disease 2025 Jul 14;16(1):524
DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus.
Ji X, Zhi M, Gu X, Han Y, Lan X, Song L, Sun P, Li J, Qi X, Feng Q
Microbiome 2025 Jul 14;13(1):164
Microbiome 2025 Jul 14;13(1):164
Hydroxychloroquine confers placental protection in antiphospholipid Syndrome: Mechanistic insights into autophagy regulation and trophoblast dysfunction.
Qi W, Cai Y, Wang X
Biochemical and biophysical research communications 2025 Jul 12;770:151994
Biochemical and biophysical research communications 2025 Jul 12;770:151994
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
Liu L, Liu X, Zhang R, Sun X, Zhang K, Zheng B, Yang R, Yang K, Song G, Zhang Z
Journal of translational medicine 2025 Jul 11;23(1):781
Journal of translational medicine 2025 Jul 11;23(1):781
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
Deng G, He Y, Gan B, Liao C, Luo X, Zheng C, Mao L
Journal of translational medicine 2025 Jul 1;23(1):714
Journal of translational medicine 2025 Jul 1;23(1):714
A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity.
Peng SQ, Wu QQ, Wang WY, Zhang YL, Zhou RN, Liao J, Wei JX, Yang Y, Shi W, Yang JL, Wang XX, Wei ZY, Sun JX, Huang L, Fan H, Cai H, Wang CK, Li XH, Li TS, Liu BC, Zhang XL, Wang B
The Journal of clinical investigation 2025 Jul 1;135(13)
The Journal of clinical investigation 2025 Jul 1;135(13)
Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO(4) in porcine ovarian granulosa cells.
Qi N, Wang B, Xing W, Li M, Liu J
Domestic animal endocrinology 2025 Jan;90:106881
Domestic animal endocrinology 2025 Jan;90:106881
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
He Z, Zheng D, Li F, Chen L, Wu C, Zeng Z, Yu C
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
Chen Y, Shen J, Yuan M, Li H, Li Y, Zheng S, Han B, Zhang C, Liu S, Sun Q, Wu J
Journal of advanced research 2025 Jan;67:331-348
Journal of advanced research 2025 Jan;67:331-348
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.
Zhang R, Lu M, Ran C, Niu L, Qi Q, Wang H
Journal of ginseng research 2025 Jan;49(1):80-91
Journal of ginseng research 2025 Jan;49(1):80-91
MYC-dependent MiR-7-5p regulated apoptosis and autophagy in diffuse large B cell lymphoma by targeting AMBRA1.
Zhang C, Wang K, Tao J, Zheng C, Zhai L
Molecular and cellular biochemistry 2025 Jan;480(1):191-202
Molecular and cellular biochemistry 2025 Jan;480(1):191-202
Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy.
Liu TY, Hao Y, Mao Q, Zhou N, Liu MH, Wu J, Wang Y, Yang MR
Chinese journal of integrative medicine 2025 Jan;31(1):19-27
Chinese journal of integrative medicine 2025 Jan;31(1):19-27
Single-cell analysis combined with transcriptome sequencing identifies autophagy hub genes in macrophages after spinal cord injury.
Ju C, Liu R, Ma Y, Dong H, Xu R, Hu H, Hao D
Clinical immunology (Orlando, Fla.) 2025 Jan;270:110412
Clinical immunology (Orlando, Fla.) 2025 Jan;270:110412
Deciphering glioblastoma pathogenesis: Insights from mitophagy dysregulation and SNX7 as a therapeutic target.
Zhang Y, Chen B, Liu R, Mei W, Lin Y
Brain research bulletin 2025 Jan;220:111184
Brain research bulletin 2025 Jan;220:111184
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
Sun Z, Ma Z, Cao W, Jiang C, Guo L, Liu K, Gao Y, Bai J, Pi J, Jiang P, Liu X
PLoS pathogens 2025 Jan;21(1):e1012872
PLoS pathogens 2025 Jan;21(1):e1012872
GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes.
Xing Y, Huang L, Jian Y, Zhang Z, Zhao X, Zhang X, Fu T, Zhang Y, Wang Y, Zhang X
Autophagy 2025 Jan;21(1):37-53
Autophagy 2025 Jan;21(1):37-53
Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity.
Zhang WK, Yan JM, Chu M, Li B, Gu XL, Jiang ZZ, Li ZM, Liu PP, Yu TM, Zhou CM, Yu XJ
Autophagy 2025 Jan;21(1):102-119
Autophagy 2025 Jan;21(1):102-119
IL-17A's role in exacerbating radiation-induced lung injury: Autophagy impairment via the PP2A-mTOR pathway.
Liu L, Yi G, Li X, Chen C, Chen K, He H, Li J, Cai F, Peng Y, Yang Z, Zhang X
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119864
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119864
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
Yang J, Wang H, Li B, Liu J, Zhang X, Wang Y, Peng J, Gao L, Wang X, Hu S, Zhang W, Hong L
Metabolism: clinical and experimental 2025 Jan;162:156041
Metabolism: clinical and experimental 2025 Jan;162:156041
Long-Term Administration of Nicotinamide Mononucleotide Mitigates High-Fat-Diet-Induced Physiological Decline in Aging Mice.
Zhou AJ, Xiong ZE, Wang L, Chen XX, Wang ZP, Zhang YD, Chen WW, Cai XL, Xu YL, Rong S, Wang T
The Journal of nutrition 2025 Jan;155(1):237-249
The Journal of nutrition 2025 Jan;155(1):237-249
POU4F1 enhances lung cancer gemcitabine resistance by regulating METTL3-dependent TWF1 mRNA N6 adenosine methylation.
Tang J, Liu Z, Xie G, Wang C, Jiang Y
3 Biotech 2025 Jan;15(1):7
3 Biotech 2025 Jan;15(1):7
Isoliquiritin targeting m5C RNA methylation improves mitophagy in doxorubicin-induced myocardial cardiotoxicity.
Fu J, Cheng L, Zhang J, Sun R, Yu M, Wu M, Li S, Cui X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156293
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156293
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Liu W, Hu J, Wang Y, Gan T, Ding Y, Wang X, Xu Q, Xiong J, Xiong N, Lu S, Wang Y, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
STIM1 promotes cervical cancer progression through autophagy activation via TFEB nuclear translocation.
Luo X, Jian M, Wu P, Wu Y, Ma Y, Feng N, Lu M, Shi D, Liu R, Ding Y, Zhang W, Fan L, He X
Cellular signalling 2025 Jan;125:111500
Cellular signalling 2025 Jan;125:111500
The BET inhibitor JQ1 suppresses tumor survival by ABCB5-mediated autophagy in uveal melanoma.
Liu W, Cui Z, Wan Q, Liu Y, Chen M, Cheng Y, Sang X, Su Y, Gu S, Li C, Liu C, Chen S, Wang Z, Wang X
Cellular signalling 2025 Jan;125:111483
Cellular signalling 2025 Jan;125:111483
Rapamycin ameliorates inflammatory pain via recovery of autophagy flux mediated by mammalian target of rapamycin (mTOR) signaling pathway in the rat spinal cord.
Zhang J, Chen S, Zhang R, Zheng X, Liu C, Zhang J, Zhang L, Yang Z, Wang L
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251317284
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251317284
A patient-specific engineered tissue model of BAG3-mediated cardiomyopathy.
Morsink MAJ, Wang BZ, Watkins JM, Zhuang RZ, Zhang X, Chesnais F, Chen C, Lock RI, Fine BM, Vunjak-Novakovic G
Journal of tissue engineering 2025 Jan-Dec;16:20417314251371296
Journal of tissue engineering 2025 Jan-Dec;16:20417314251371296
Gboxin Induced Apoptosis and Ferroptosis of Cervical Cancer Cells by Promoting Autophagy-Mediated Inhibition of Nrf2 Signaling Under Low-Glucose Conditions.
Liu W, Lu J, Li J, Wang L, Chen Y, Wu Y, Zhang Z, Zhang J, Gao F, Jia C, Bao Y, Yang X, Song Z
International journal of molecular sciences 2025 Jan 9;26(2)
International journal of molecular sciences 2025 Jan 9;26(2)
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Xu L, Zhou S, Li J, Yu W, Gao W, Luo H, Fang X
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1.
Yuan Y, Lai S, Hu T, Hu F, Zou C, Wang X, Fang M, Liu J, Huang H
Scientific reports 2025 Jan 4;15(1):794
Scientific reports 2025 Jan 4;15(1):794
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Zhang JL, Wang XF, Li JL, Duan C, Wang JF
Veterinary research 2025 Jan 31;56(1):23
Veterinary research 2025 Jan 31;56(1):23
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
You Q, Wu J, Lyu R, Cai Y, Jiang N, Liu Y, Zhang F, He Y, Chen D, Wu Z
BMC microbiology 2025 Jan 29;25(1):53
BMC microbiology 2025 Jan 29;25(1):53
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
Wei M, Jiang Q, Bian S, Chang P, Li B, Shi C, Zhu Y, Wang Y, Hou P, Li J
Journal of nanobiotechnology 2025 Jan 29;23(1):54
Journal of nanobiotechnology 2025 Jan 29;23(1):54
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Wu X, Li Y, Wang W, Xu J, Zhao B, Sun W, Ge D, Xiong L, Dou X, Zou X, Wang L, Chen M
Scientific reports 2025 Jan 28;15(1):3542
Scientific reports 2025 Jan 28;15(1):3542
ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer.
Shi B, Chen J, Guo H, Shi X, Tai Q, Chen G, Yao H, Mi X, Zhong R, Lu Y, Zhao Y, Sun L, Zhou D, Yao Y, He S
Scientific reports 2025 Jan 23;15(1):2992
Scientific reports 2025 Jan 23;15(1):2992
Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors.
Shekhar S, Tracy C, Lidsky PV, Andino R, Wert KJ, Krämer H
Nature communications 2025 Jan 2;16(1):252
Nature communications 2025 Jan 2;16(1):252
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis.
Xia B, Lu YL, Peng J, Liang JW, Li FQ, Ding JY, Wan CW, Le CY, Dai JL, Jie-Wang, Guo B, Huang J
Scientific reports 2025 Jan 2;15(1):603
Scientific reports 2025 Jan 2;15(1):603
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
Yu C, Zhang C, Zhang Q, Zhang C, Han J, Li J
iScience 2025 Jan 17;28(1):111590
iScience 2025 Jan 17;28(1):111590
Heat Tolerance-Associated circRNA3685 Regulates Apoptosis and Autophagy in Bovine Mammary Epithelial Cells via Sponging bta-miR-138.
Zhang C, Hu L, Wang S, Chen G, Brito LF, Li B, Xu Q, Wang Y
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1656-1671
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1656-1671
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress.
Deng H, Taishi Y, Wang G, Kong Y, Zhang R, Zheng X
Ecotoxicology and environmental safety 2025 Jan 15;290:117566
Ecotoxicology and environmental safety 2025 Jan 15;290:117566
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice.
Sun S, Yu T, Huh JY, Cai Y, Yoon S, Javaid HMA
Skeletal muscle 2025 Jan 13;15(1):2
Skeletal muscle 2025 Jan 13;15(1):2
Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J
bioRxiv : the preprint server for biology 2025 Jan 13;
bioRxiv : the preprint server for biology 2025 Jan 13;
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
Zheng K, Jin G, Cao R, Gao Y, Xu J, Chai R, Kang Y
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
Xie X, Li H, Luo B, Fan X, Li Y, Zhang Y, Cui X, Yin W, Liu B, Xu H, Cheng H, Li W, Yu H, Wu F
International immunopharmacology 2025 Jan 10;144:113670
International immunopharmacology 2025 Jan 10;144:113670
CAVIN2 attenuates ventilator-induced lung injury in rats by MAPK/ERK1/2 signaling pathway.
Zhu Q, Wu K, Lv J, Yang R, Li C, Liu W, Zhang J, Lian S, Wang L, Zhang X
International immunopharmacology 2025 Jan 10;144:113669
International immunopharmacology 2025 Jan 10;144:113669
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Zhao B, Tan WL, Yu BB, Fan J, Liu C, Liu J, Liu Z
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Molecular and cellular endocrinology 2025 Jan 1;595:112392
LC3B-regulated autophagy mitigates zinc oxide nanoparticle-induced epithelial cell dysfunction and acute lung injury.
Chen R, Luo S, Zhang Y, Mao L, Diao J, Cheng S, Zou Z, Chen C, Qin X, Jiang X, Zhang J
Toxicological sciences : an official journal of the Society of Toxicology 2025 Jan 1;203(1):105-117
Toxicological sciences : an official journal of the Society of Toxicology 2025 Jan 1;203(1):105-117
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, Zhang Z, Tang M, Shi C, Xu Y
Neural regeneration research 2025 Jan 1;20(1):253-264
Neural regeneration research 2025 Jan 1;20(1):253-264
Bradykinin attenuates NiSO(4)-induced autophagy in MIN6 cells and protects islet function in mice by regulating the PI3K/AKT/mTOR signaling pathway.
Wang Z, Chen H
Biochemical and biophysical research communications 2025 Feb;746:151265
Biochemical and biophysical research communications 2025 Feb;746:151265
Dimethyl fumarate alleviate hepatic ischemia-reperfusion injury through suppressing cGAS-STING signaling.
Xiong Y, Chen J, Li K, Liang W, Song J, Qiu X, Zhang B, Qiu D, Qin Y
MedComm 2025 Feb;6(2):e70077
MedComm 2025 Feb;6(2):e70077
Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson's disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle.
Wang SS, Peng Y, Fan PL, Ye JR, Ma WY, Wu QL, Wang HY, Tian YJ, He WB, Yan X, Zhang Z, Chu SF, Chen NH
Acta pharmacologica Sinica 2025 Feb;46(2):308-325
Acta pharmacologica Sinica 2025 Feb;46(2):308-325
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
Puerarin Reversing Autophagy-Lysosomal Dysfunction via Acid Sphingomyelinase Inhibition in Cardiomyocytes.
Li YP, He Q, Yu XY, Xiong ST, You HJ, Xuan Y, Liao WY, Chen ZY, Li HY, Wang W, Chen Y, Wang X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70427
Journal of cellular and molecular medicine 2025 Feb;29(4):e70427
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
Jiang H, Xie Y, Hu Z, Lu J, Zhang J, Li H, Zeng K, Peng W, Yang C, Huang J, Han Z, Bai X, Yu X
PLoS biology 2025 Feb;23(2):e3002961
PLoS biology 2025 Feb;23(2):e3002961
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
Zhang Z, Chen S, Jun S, Xu X, Hong Y, Yang X, Zou L, Song YQ, Chen Y, Tu J
Autophagy 2025 Feb;21(2):424-446
Autophagy 2025 Feb;21(2):424-446
Impaired degradation of PLCG1 by chaperone-mediated autophagy promotes cellular senescence and intervertebral disc degeneration.
Cheng Z, Gan W, Xiang Q, Zhao K, Gao H, Chen Y, Shi P, Zhang A, Li G, Song Y, Feng X, Yang C, Zhang Y
Autophagy 2025 Feb;21(2):352-373
Autophagy 2025 Feb;21(2):352-373
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Papoutsi E, Steiner JL, Gordon B, Haynatzki G, Pacher P, Koutakis P
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
Ji J, Chen YF, Hong C, Ren XW, Xu H, Cai ZY, Dong YF, Sun XL
Journal of neurochemistry 2025 Feb;169(2):e70013
Journal of neurochemistry 2025 Feb;169(2):e70013
N(6)-Methyladenosine modification mediated by METTL3 promotes DNA-PKcs expression to induce anlotinib resistance in osteosarcoma.
Zhang Y, Shen G, Zhang D, Meng T, Lv Z, Chen L, Li J, Li K
Clinical and translational medicine 2025 Feb;15(2):e70228
Clinical and translational medicine 2025 Feb;15(2):e70228
Natural molecule isoliquiritigenin mitigates MASH and liver fibrosis in mice by promoting autophagy through the PI3K/Akt signaling pathway.
Liu R, Zhang Y, Liu M, Shang Z, Song S, Zhang Y, Zhou Y, Tu C
The Journal of nutritional biochemistry 2025 Feb;136:109808
The Journal of nutritional biochemistry 2025 Feb;136:109808
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Lv Y, Song B, Yang G, Wang Y, Wu Z, Si M, Yang Z, Chen H, Liu C, Li M, Zhang Y, Qiao Z, Wang L, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Beclin1 regulates yak endometrial inflammation and TLR4/NF-κB signaling pathway through autophagy/non-autophagy function.
Ma W, Wang L, Pan Y, Wang M, Wang J, Feng M, Wang J, Zhang H, Zhang R, Jiao Z, Cui Y, Yu S
International immunopharmacology 2025 Feb 6;147:113940
International immunopharmacology 2025 Feb 6;147:113940
Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1.
Lin K, Wei L, Wang R, Li L, Song S, Wang F, He M, Pu W, Wang J, Wazir J, Cao W, Yang X, Treuter E, Fan R, Wang Y, Huang Z, Wang H
Cell metabolism 2025 Feb 4;37(2):460-476.e8
Cell metabolism 2025 Feb 4;37(2):460-476.e8
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Exposure to Nanoplastics During Pregnancy Induces Brown Adipose Tissue Whitening in Male Offspring.
Shen Z, Tian K, Tang J, Wang L, Zhang F, Yang L, Ge Y, Jiang M, Zhao X, Yang J, Chen G, Wang X
Toxics 2025 Feb 27;13(3)
Toxics 2025 Feb 27;13(3)
Bone marrow mesenchymal stem cells alleviate neurological dysfunction by reducing autophagy damage via downregulation of SYNPO2 in neonatal hypoxic-ischemic encephalopathy rats.
Xue LL, Cheng J, Du RL, Luo BY, Chen L, Xiao QX, Zhou HS, She HQ, Wang SF, Chen TB, Hu CY, He YQ, Wang TH, Xiong LL
Cell death & disease 2025 Feb 25;16(1):131
Cell death & disease 2025 Feb 25;16(1):131
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer.
Huo L, Huang X, Wang Y, Ouyang Y, Zheng X, Ouyang Y, Cao X, Chen K, Wei D, Wu Y, Zhang R, Lin Y, Kang T, Gao Y
Cell death & disease 2025 Feb 25;16(1):130
Cell death & disease 2025 Feb 25;16(1):130
RNF167 mediates atypical ubiquitylation and degradation of RLRs via two distinct proteolytic pathways.
He M, Yang Z, Xie L, Chen J, Liu S, Lu L, Li Z, Zheng B, Ye Y, Lin Y, Bu L, Xiao J, Zhong Y, Jia P, Li Q, Liang Y, Guo D, Li CM, Hou P
Nature communications 2025 Feb 24;16(1):1920
Nature communications 2025 Feb 24;16(1):1920
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
Gu L, Wang S, Zhou L, Wang W, Bao Y, He Y, Yang T, Sun J, Jiang Q, Shan T, Du C, Wang Z, Wang H, Xie L, Gu A, Zhao Y, Ji Y, Wang Q, Wang L
Communications biology 2025 Feb 23;8(1):292
Communications biology 2025 Feb 23;8(1):292
Paeoniflorin Inhibits Porcine Circovirus Type 2 Replication by Inhibiting Autophagy and Targeting AKT/mTOR Signaling.
Wu Z, Yu L, Hu Y, Bao W, Wu S
Veterinary sciences 2025 Feb 2;12(2)
Veterinary sciences 2025 Feb 2;12(2)
Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling.
Xia H, Tai XJ, Cheng W, Wu Y, He D, Wang LF, Liu H, Zhang SY, Sun YT, Liu HZ, Liu DD, Zhao HZ, Ji FY, Li XH
Scientific reports 2025 Feb 19;15(1):6081
Scientific reports 2025 Feb 19;15(1):6081
BLM knockdown promotes cells autophagy via p53-AMPK-mTOR pathway in triple negative breast cancer cells.
Wang L, Wang Y, Chen C, Li Y, Dong H, Yao T, Jin G, Wang Z
Molecular biology reports 2025 Feb 18;52(1):243
Molecular biology reports 2025 Feb 18;52(1):243
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Zhao X, Xu Y, Li S, Bai S, Zhang W, Zhang Y
Biomolecules 2025 Feb 18;15(2)
Biomolecules 2025 Feb 18;15(2)
Layered Double Hydroxide LDH-Loaded miR-141-3p Targets RAB10 Suppressing Cellular Autophagy to Reverse Paclitaxel Resistance in Breast Cancer.
Tao S, Ji Y, Li R, Xiao Y, Wu H, Ye R, Shi J, Geng C, Tang G, Ran R, Zhu C, Wang W, Chen C, Yang Q
ACS omega 2025 Feb 18;10(6):5886-5899
ACS omega 2025 Feb 18;10(6):5886-5899
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Wang F, Xiao W, Li J, Zhang Z, Zhang X, Sun J, Zhong Y, Wang X, Zhuang R, Gu X
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Biochemical and biophysical research communications 2025 Feb 16;749:151385
In situ architecture of the intercellular organelle reservoir between epididymal epithelial cells by volume electron microscopy.
Li X, Qiao F, Guo J, Jiang T, Lou H, Li H, Xie G, Wu H, Wang W, Pei R, Liu S, Ye M, Li J, Huang S, Zhang M, Ma C, Huang Y, Xu S, Li X, Sun X, Yu J, Fok KL, Duan S, Chen H
Nature communications 2025 Feb 15;16(1):1664
Nature communications 2025 Feb 15;16(1):1664
The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance.
Xu Y, Wang Q, Wang J, Qian C, Wang Y, Lu S, Song L, He Z, Liu W, Wan W
Immunity 2025 Feb 11;58(2):309-325.e6
Immunity 2025 Feb 11;58(2):309-325.e6
Hypoxia Regulates the Proliferation and Apoptosis of Coronary Artery Smooth Muscle Cells Through HIF-1α Mediated Autophagy in Yak.
Yang S, Cui Y, Ma R, Yu S, Zhang H, Zhao P, He J
Biomolecules 2025 Feb 10;15(2)
Biomolecules 2025 Feb 10;15(2)
INHIBITING SIRT2 ATTENUATES SEPSIS-INDUCED ACUTE KIDNEY INJURY VIA FOXO1 ACETYLATION-MEDIATED AUTOPHAGY ACTIVATION.
Yu B, Weng L, Li J, Wang T, Qiu W, Li Y, Shi M, Lin B, Lin X, Chen Z, Zeng Z, Gao Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):255-266
Shock (Augusta, Ga.) 2025 Feb 1;63(2):255-266
Aggregatin is a mitochondrial regulator of MAVS activation to drive innate immunity.
Gao J, Ding M, Xiyang Y, Qin S, Shukla D, Xu J, Miyagi M, Fujioka H, Liang J, Wang X
Journal of immunology (Baltimore, Md. : 1950) 2025 Feb 1;214(2):238-252
Journal of immunology (Baltimore, Md. : 1950) 2025 Feb 1;214(2):238-252
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
Zhang J, Fu Z, Wen F, Lyu P, Huang S, Cai X, Zhang Z, Zhang Y, Fan C, Man W, Sun X, Huang Y
Journal of neurophysiology 2025 Feb 1;133(2):490-501
Journal of neurophysiology 2025 Feb 1;133(2):490-501
Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection.
Zeng Q, Huang BX, Liu C, Liang N, Yu J, Liao SJ
Molecular neurobiology 2025 Dec;62(12):15628-15646
Molecular neurobiology 2025 Dec;62(12):15628-15646
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Jie L, Zhang Y, Liu J, Fu H, Zhu Z, Huang Z, Shi X, Wang P, Yin S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
Guo R, Chen MN, Lin QH, Qi HM, Wang XQ, Li BY, Wang S, Xu SJ, Zhang Y, Liu W
Inflammation 2025 Dec;48(6):4094-4109
Inflammation 2025 Dec;48(6):4094-4109
RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression.
Liu X, Wang W, Cao W, Li Z, Huang H, Liu F, Wang Y, Zhong Z, Zhang H, Pei X, Chen H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):2001-2015
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):2001-2015
Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis.
Feng J, Chen R, Chen Y, Deng J, Wei J
Renal failure 2025 Dec;47(1):2538268
Renal failure 2025 Dec;47(1):2538268
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351
Biochemistry and biophysics reports 2025 Dec;44:102351
Integrating superlubricative nanomaterials with precision drug delivery for advanced osteoarthritis therapy.
Gan X, Li J, Li S, Wang X, Wang Q, Chen X, Huang Y, Nie M, Kang H, Dai H
Materials today. Bio 2025 Dec;35:102359
Materials today. Bio 2025 Dec;35:102359
Biomolecule-tailored chiral nickel oxide nanozymes amplify autophagy-mediated tumor ablation via synergistic photodynamic-chemodynamic therapy.
Pang W, Shao Y, Xu H, Li T, Wu L, Liu Z, Zhang L, Chen W, Li Y, Xu D, Cheng J, Xu X
Materials today. Bio 2025 Dec;35:102303
Materials today. Bio 2025 Dec;35:102303
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Huang Y, Liu Q, Chen L, Tan X, Zeng D, Zhang Y, Qin J, Zeng F, Wei X, Zhong Q, Zhang J, Yuan D
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
Electroacupuncture Improves Pregnancy Outcomes of Assisted Reproduction and Mitochondrial Function of Granulosa Cells in Patients with Polycystic Ovary Syndrome of Phlegm-Dampness Syndrome.
Pang CH, Guo DY, Wang Q, Wang KH, Lian F
Chinese journal of integrative medicine 2025 Dec;31(12):1105-1112
Chinese journal of integrative medicine 2025 Dec;31(12):1105-1112
COX-2 targeting Ru-arene complexes from metal-ligand synergistic enhancement strategy for breast cancer therapy.
Zhang GD, Hao W, Yu ZH, Liu HK, Su Z
Journal of inorganic biochemistry 2025 Dec;273:113044
Journal of inorganic biochemistry 2025 Dec;273:113044
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
Chen H, Zhu M, Zhao Z, Jiang Y, Wang H, Liu Y, Chen Y, Li H, Xun C, Hui H
Pharmacological research 2025 Dec;222:108050
Pharmacological research 2025 Dec;222:108050
Dysfunctional autophagy triggers STING1 activation to exacerbate cartilage degeneration in obesity-associated osteoarthritis.
Kang X, Liu W, Ma X, Feng D, Sun H, Wu S
Autophagy 2025 Dec;21(12):3344-3360
Autophagy 2025 Dec;21(12):3344-3360
Inflammatory signaling attenuates spliceosome function and cognitive ability.
Lin L, Huang X, Huang C, Zou J, Hu M, Lan T, Wang H, Du Z, Tian M, Liu J, Dong H, Liu B, Cheng H, Zhou L, Chen Y, Zhou R
Autophagy 2025 Dec;21(12):3123-3141
Autophagy 2025 Dec;21(12):3123-3141
Deacetylation of ATG16L1 is required for LC3-associated lysosomal microautophagy.
Wang Q, Wan W, Zhang H, Zhou T, Shen HM, Huang P, Liu W
Autophagy 2025 Dec;21(12):2948-2962
Autophagy 2025 Dec;21(12):2948-2962
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
Fiesel FC, Bustillos BA, Watzlawik JO, Chen CXQ, Berryer MH, Zhang J, Boneski PK, Hayes CS, Bredenberg JM, Deneault E, You Z, Abdien N, Aprahamian N, Goldsmith TM, Baninameh Z, Cocker LT, Zhang H, Goldberg MS, Fon EA, Trempe JF, Virdee S, Durcan TM, Springer W
Autophagy 2025 Dec;21(12):2750-2770
Autophagy 2025 Dec;21(12):2750-2770
Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication.
Zhou Q, Shi D, Tang YD, Zhang L, Liu H, Ye G, Zhang Z, Hu B, Huang L, Weng C
Autophagy 2025 Dec;21(12):2597-2613
Autophagy 2025 Dec;21(12):2597-2613
MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma.
Ye F, Zhang H, Chen Q, Gui Y, Tian G, Ye Y, Chen X, Dong H, Fan X, Chen J, Yuan R, Zhao L, Yu J
Cell adhesion & migration 2025 Dec;19(1):2515763
Cell adhesion & migration 2025 Dec;19(1):2515763
Comparative Evaluation of Spores and Vegetative Forms of Bacillus subtilis and Bacillus licheniformis on Probiotic Functionality In Vitro and In Vivo.
Xie H, Yu T, Zhou Q, Na K, Lu S, Zhang L, Guo X
Probiotics and antimicrobial proteins 2025 Dec;17(6):4709-4727
Probiotics and antimicrobial proteins 2025 Dec;17(6):4709-4727
Laminar double hydroxide-loaded miR-654-3p targets POU2F1-mediated metabolic reprogramming against colorectal cancer.
Shi J, Zhu C, Xu S, Ran R, Ye R, Xiao Y, Ji Y, Geng C, Tang G, Li R, Ding Y, Wang W, Yang Q, Chen C
Bioorganic chemistry 2025 Dec;167:109234
Bioorganic chemistry 2025 Dec;167:109234
Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77.
Hu S, Li X, Yu M, Zhang H, Wang X, Qi C, Huang S, Xu Z, Hu H, Chen S, Fang M, Zeng J
Bioorganic chemistry 2025 Dec;167:109113
Bioorganic chemistry 2025 Dec;167:109113
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Zhang Y, Tao C, Yin X, Wang Z, Zhang Y, Yu J, Wang Y, Han W
Clinical and translational medicine 2025 Dec;15(12):e70556
Clinical and translational medicine 2025 Dec;15(12):e70556
Ginsenoside Rb1 alleviates atherosclerosis by modulating vascular smooth muscle cell proliferation, foam cell formation, and autophagy.
Yuan HH, Yi ZY, Xie LL, Bu LL, Guo MH, Zheng XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157503
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157503
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
Zhang J, Li X, Sun L, Chen B, Zhang R, Duan J
The Journal of nutritional biochemistry 2025 Dec;146:110080
The Journal of nutritional biochemistry 2025 Dec;146:110080
PARP inhibitors accumulate B7-H3 on fibroblasts via blocking autophagic flux to potentiate immune evasion in ovarian cancer.
Fang T, Xia Y, Li Y, Xu S, Li H, Wang S, Huang P, Qian Y, Jin P, Jin N, Xu C, Wang Z, Xiong X, Wang M, Zhou D, Wang Y, Li X, Xu T, Zhang Q, Liu D, Fang Y, Zhao GN, Gao Q
Oncoimmunology 2025 Dec;14(1):2516294
Oncoimmunology 2025 Dec;14(1):2516294
Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.
Zhao X, Wang L, Huang S, Liu L, Wang X, Pu L, Chen H, Nie J
Reproductive toxicology (Elmsford, N.Y.) 2025 Dec;138:109048
Reproductive toxicology (Elmsford, N.Y.) 2025 Dec;138:109048
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Dan Z, Liu W, Zhang H, Shi X, Zhu R, Yang M, Wang Y, Zhu H
Cellular signalling 2025 Dec;136:112080
Cellular signalling 2025 Dec;136:112080
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Inhibitory Effect of Sirtuin6 on EndMT by Regulating Oxidative Stress and Autophagy in Coxsackievirus B3-Induced Cardiac Endothelial Cells.
Yang Z, Wang Y, Chen J, Shou X, Zhang D, Zhou Z, Liu Q
Immunity, inflammation and disease 2025 Dec;13(12):e70316
Immunity, inflammation and disease 2025 Dec;13(12):e70316
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Zhang X, Su Y, Yang W, Song Z, Sun Z, Wu X, Chen J, Gao B, Wang Z, Wang L, Jiang Q, Bu L, Li J, Lin Y, Xie W, Li J, Guo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16-OPTN Axis in Glioblastoma.
Chang H, Hou J, Hu X, Hou N, Xu M, Du Y, Xu J, Wang Y, Xie Z, Shi J, Zhang Y, Cui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e02915
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e02915
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Yang Y, Li M, Wang J, Zhang H, Chang R, Zhao B, Aernouts B, Huang Q, Xu C
Journal of dairy science 2025 Dec;108(12):13919-13937
Journal of dairy science 2025 Dec;108(12):13919-13937
FUT3-B3GNT3 interaction promotes pancreatic cancer progression and chemoresistance via NF-κB signaling mediated autophagy.
Jin L, Han W, Zou J, Tang X, Chen P, Xie H, Zhou B, Qian D, Yu Y
European journal of medical research 2025 Dec 9;30(1):1223
European journal of medical research 2025 Dec 9;30(1):1223
OPRK1 drives SLC9A3R1 progression to neuroendocrine prostate cancer.
Liang L, Shen Z, Zhang Y, Cheng Y, Yao B, Feng N, Zhao R
Cell death & disease 2025 Dec 7;17(1):68
Cell death & disease 2025 Dec 7;17(1):68
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Deng Y, Jiang X, Che Z, Shang Y, Hu M, Wang W, Yu W, Yang B, Liu X
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Journal of nanobiotechnology 2025 Dec 6;23(1):767
A20 Attenuates Inflammatory Injury in Bovine Endometrial Epithelial Cells Through Autophagy-Mediated NLRP3 Inflammasome Inactivation.
Jiang Y, Fei F, Wang X, Jiang Y, Liu K, Guo L, Cui L, Wang H, Dong J, Li J
Animals : an open access journal from MDPI 2025 Dec 5;15(24)
Animals : an open access journal from MDPI 2025 Dec 5;15(24)
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Mecca M, Sichetti M, Spina E, Giuseffi M, Giglio E, Picerno S, Valvano L, Statuto T, Santarsiere A, Funicello M, Armentano MF, Chiummiento L, Lupattelli P, Romano A, Giordano A, Cortellino S
Cancer cell international 2025 Dec 23;26(1):44
Cancer cell international 2025 Dec 23;26(1):44
Lysosomal escape and TMEM106B fibrillar core determine TDP-43 seeding outcomes.
Zhong W, Scialò C, Gatta B, Häfliger M, Leu N, Lurati F, Peter M, Ramesh N, Roschitzki B, Jagannath S, Manglunia R, de Cecco E, Lim SM, Wilkins OG, Aguzzi A, Ward M, Fratta P, Petrucelli L, Lagier-Tourenne C, Polymenidou M
bioRxiv : the preprint server for biology 2025 Dec 22;
bioRxiv : the preprint server for biology 2025 Dec 22;
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Zhao C, Liu J, Zhao S, Liu P, Li Z, Li Y, Dong R, Wang XL
Physiological research 2025 Dec 2;74(5):871-884
Physiological research 2025 Dec 2;74(5):871-884
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Gao X, Huang G, Hao R, Wang L, Ma A, Zhang Z, Zhao T
iScience 2025 Dec 19;28(12):114022
iScience 2025 Dec 19;28(12):114022
Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy-lysosomal pathway: an experimental study.
Wang A, An Y, Wang X, Gou W, Xu F, Li Y, Wang C, Tu Z, Hou W, Cui Y
International journal of surgery (London, England) 2025 Dec 17;112(4):9262-81
International journal of surgery (London, England) 2025 Dec 17;112(4):9262-81
Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.
Xue WH, Zhang X, Guo S, Yu H, Man RY, Lu PF, Ge GH, Liu HY, Meng FH, Zhang TJ
European journal of medicinal chemistry 2025 Dec 15;300:118151
European journal of medicinal chemistry 2025 Dec 15;300:118151
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Song HC, Li DL, Wang JJ, Jiao HJ, Li MW, Zhao L, Yang XH, Yan M
Parasites & vectors 2025 Dec 15;19(1):38
Parasites & vectors 2025 Dec 15;19(1):38
Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus.
Tao L, Teng L, Ge M, Wang Y, Hu C, Chen J, Zhao J, Cheng L, Zhang Z, Qin W, Jia Y, Mi D, Yuan Z, Chen L
Nature communications 2025 Dec 15;16(1):11117
Nature communications 2025 Dec 15;16(1):11117
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
Liu S, Guan H, Wang F
International immunopharmacology 2025 Dec 10;167:115667
International immunopharmacology 2025 Dec 10;167:115667
PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13.
Lou J, Zhu H, Yang Z, Jiang P, Liu G, Wang X
mBio 2025 Dec 10;16(12):e0239625
mBio 2025 Dec 10;16(12):e0239625
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Liu J, Zhang C, Ma R, Yin C, Ren J, Yang S, Zhao Y, Tang Y, Wei J, Li X
Free radical biology & medicine 2025 Dec 1;240:514-531
Free radical biology & medicine 2025 Dec 1;240:514-531
Hemorrhagic shock and reperfusion induced cognitive impairment through HIF3α/SIRT1.
Xue S, Wang J, Tian Y, Zong T, Zhang Y, Zhou X, Li M, He S, Yan W, Zhang Y, Hu X, Huang C
Free radical biology & medicine 2025 Dec 1;240:491-503
Free radical biology & medicine 2025 Dec 1;240:491-503
LC3-dependent intercellular transfer of phosphorylated STAT1/2 elicits CXCL9+ macrophages and enhances radiation-induced antitumor immunity.
Li JY, Li YQ, Dai JH, Gong S, He QM, Bai JW, Huang SW, Lu YQ, Duan YF, Feng SY, Tan XR, Liang XY, Ma J, Guo R, Liu N
The Journal of clinical investigation 2025 Dec 1;135(23)
The Journal of clinical investigation 2025 Dec 1;135(23)
Effect of spermidine on cuproptosis in follicular granulosa cells.
Li S, Qi Y, Qi Y, Wang Z, Xu S, Xiao T, Zhu Y, Zheng W, Wang X, Jiang D, Kang B
British poultry science 2025 Aug;66(4):539-546
British poultry science 2025 Aug;66(4):539-546
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Xu J, Hu M, Li Y, Gong H, Zhang X, He Z, Xiao C, Yang C, Zeng J
Cell biology international 2025 Aug;49(8):1042-1055
Cell biology international 2025 Aug;49(8):1042-1055
SDF2L1 downregulation mediates high glucose-caused Schwann cell dysfunction by inhibiting nuclear import of TFEB and CREB via KPNA3.
Jin T, Li F, Wei W, Li Q, Gao Y, Yuwen C, Sun Y, Li W, Zhu L, Hao J
Experimental neurology 2025 Aug;390:115273
Experimental neurology 2025 Aug;390:115273
Zn(2+)-driven metformin conjugated with siRNA attenuates osteoarthritis progression by inhibiting NF-κB signaling and activating autophagy.
He H, Huang C, Huang H, Lan N, Liu S, Luo Y, Zheng L, Liu G, Qin Z, Zhao J
Biomaterials 2025 Aug;319:123210
Biomaterials 2025 Aug;319:123210
H3K36me2 methyltransferase NSD2/WHSC1 promotes triple-negative breast cancer metastasis via activation of ULK1-dependent autophagy.
Chen D, Chen X, Yang M, Li Q, Weng S, Kou S, Liu X, Jiang G, Liu H
Autophagy 2025 Aug;21(8):1824-1842
Autophagy 2025 Aug;21(8):1824-1842
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
Chen B, Liu B, Chen J, Li W, Ma N, Liu J, Fan R, Hu Q, Song H, Xu Y, Jiang T, Song J
Autophagy 2025 Aug;21(8):1680-1699
Autophagy 2025 Aug;21(8):1680-1699
FKBP10 Silencing Alleviates Gluteal Muscle Contracture by Inhibiting Fibrosis and Restoring Autophagy via HSP47/SMAD3 Pathway Inactivation.
Xu H, Yao J, Jin Q, Yao J, Ren L, Zhu J, Luo W, Zheng P, Li L, Zhou J
The American journal of pathology 2025 Aug;195(8):1504-1522
The American journal of pathology 2025 Aug;195(8):1504-1522
TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy.
Jin W, Lu D, Wei W, Wang M, Chen R, Yan F, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167866
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167866
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
Wu F, Li C, Song X, Xie L
Cellular signalling 2025 Aug;132:111834
Cellular signalling 2025 Aug;132:111834
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
Kong X, Gu H, Zhang Y, Meng Q, Li Q, Song K, Li Y, Liu K, Liu Z, Hu R, Zhai H, Li T, Ling Z, Wei Z, Wei F, Cheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8-AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma.
Chen ZW, Shan JJ, Chen M, Wu Z, Zhao YM, Zhu HX, Jin X, Wang YX, Wu YB, Xiang Z, Ding ZW, Lin ZH, Wang LR, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01042
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01042
Whey protein hydrolysate alleviated acetaminophen-induced hepatocyte pyroptosis by activating mitophagy.
Zhang S, Guo J, Liu M, Chen Y, Shen X, Wang J, Deng X, Guan S
Journal of dairy science 2025 Aug;108(8):7896-7911
Journal of dairy science 2025 Aug;108(8):7896-7911
HSP90 deficiency promotes cholesteryl ester accumulation in lipid droplets via endocytosis of low-density lipoprotein.
Ma C, Che X, Liang Y, Li J, Yu K, Zhao TJ, Li P, Chen FJ
Communications biology 2025 Aug 6;8(1):1169
Communications biology 2025 Aug 6;8(1):1169
DHRS9 promotes malignant progression of ovarian cancer through SQSTM1.
Wu Y, Meng S, Zhao H, Tan B, Gao J, Du J, Meng X
Journal of cancer research and clinical oncology 2025 Aug 27;151(8):236
Journal of cancer research and clinical oncology 2025 Aug 27;151(8):236
PP2A attenuates α-amanitin-induced liver injury by promoting autophagy and inhibiting apoptosis in mouse models.
Xu H, Sun J, Zhao Y, Zhou Y, Wang K, Liu X, Yang J, Wu P, Wang S, Kastelic JP, Qu W, Zhang L, Gu X
Chemico-biological interactions 2025 Aug 25;417:111558
Chemico-biological interactions 2025 Aug 25;417:111558
Pure platelet-rich plasma delays intervertebral disc degeneration by activating SIRT1-mediated autophagy in nucleus pulposus cells.
Han J, Ding Z, Huang J, Zhang Y, Ding Y
Journal of orthopaedic surgery and research 2025 Aug 22;20(1):786
Journal of orthopaedic surgery and research 2025 Aug 22;20(1):786
Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis.
Pan Z, Yu F, You W, Li F, Cui F, Guo J, Yang Z
Oncogenesis 2025 Aug 21;14(1):31
Oncogenesis 2025 Aug 21;14(1):31
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
Huang H, Cui J, Tang D, Xiang X, Mao J, He Z, Hu H, He Z, He L, Tang H
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
Comprehensive Transcriptomic and m6A Epitranscriptomic Analysis Reveals Colchicine-Induced Kidney Toxicity via DNA Damage and Autophagy in HK2 Cells.
Tian K, Wen J, Zhang D, Lin J, Weng L, Yang L, Zhao W, Li C, Zhu A
Toxins 2025 Aug 14;17(8)
Toxins 2025 Aug 14;17(8)
Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation.
Qu F, Jian W, Huang Y, Zhou X, Wang X, Li J, Wang G, Mainly
Cellular and molecular life sciences : CMLS 2025 Aug 13;82(1):309
Cellular and molecular life sciences : CMLS 2025 Aug 13;82(1):309
Hepatocyte-Enriched miRNA-193b-3p Promotes Hepatitis B Virus Replication by Dual Activation of Viral Core Promoter Activity and Autophagy Induction by Targeting IGF-1R.
Deng Y, Zheng J, Li F, Zou H, Tian S, Zhao Z, Zeng H, Zhai Y, Deng W, Zhang J, Lu M, Jia B, Lin Y
Journal of medical virology 2025 Apr;97(4):e70330
Journal of medical virology 2025 Apr;97(4):e70330
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Yang Q, Yang C, Lv H, Zheng X, Mao S, Liu N, Mo S, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Shang J
Inflammation 2025 Apr;48(2):541-556
Inflammation 2025 Apr;48(2):541-556
Clomiphene and dexamethasone inhibit apoptosis and autophagy via the ROS-JNK/MAPK-P21 signaling pathway in PCOS.
Liu R, Tang Y, Chen X, Shang X
Histology and histopathology 2025 Apr;40(4):555-570
Histology and histopathology 2025 Apr;40(4):555-570
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.
Wang G, Dai S, Chen J, Zhang K, Huang C, Zhang J, Xie K, Lin F, Wang H, Gao Y, Yin L, Jiang K, Miao Y, Lu Z
Cell death and differentiation 2025 Apr;32(4):702-713
Cell death and differentiation 2025 Apr;32(4):702-713
VDAC1 Inhibition Protects Against Noise-Induced Hearing Loss via the PINK1/Parkin Pathway.
Jin Y, Dong W, Jiang Y, Dong L, Li Z, Yu D
CNS neuroscience & therapeutics 2025 Apr;31(4):e70410
CNS neuroscience & therapeutics 2025 Apr;31(4):e70410
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Yan C, Dong T, Shan Y, Zhao B, Yang H, Cai Y, Li S, Liu Q, Chu Y, Hao H, Cheng Z, Liu M, Zhang Y
Veterinary microbiology 2025 Apr;303:110446
Veterinary microbiology 2025 Apr;303:110446
Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J
Nature cell biology 2025 Apr;27(4):619-632
Nature cell biology 2025 Apr;27(4):619-632
Dietary cinnamon promotes longevity and extends healthspan via mTORC1 and autophagy signaling.
Guo Y, Zhang Q, Zhang B, Pan T, Ronan EA, Huffman A, He Y, Inoki K, Liu J, Xu XZS
Aging cell 2025 Apr;24(4):e14448
Aging cell 2025 Apr;24(4):e14448
Overexpression of hnRNPK and inhibition of cytoplasmic translocation ameliorate lipid disorder in doxorubicin-induced cardiomyopathy via PINK1/Parkin-mediated mitophagy.
Xu Q, Wang X, Hu J, Wang Y, Lu S, Xiong J, Li H, Xiong N, Huang Y, Wang Y, Wang Z
Free radical biology & medicine 2025 Apr;231:94-108
Free radical biology & medicine 2025 Apr;231:94-108
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L, Wang Y, Wang C
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Chemistry & biodiversity 2025 Apr;22(4):e202401873
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Zhang S, Nie F, Zeng Y, Yang Z, Song W, Yan X, Tang Z, Fu Y, Guo R
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Novel Parkin agonists from Poria cocos against dyslipidemia.
He X, Tao Y, Song C, He J, Gong D, Yu W, Wang H, Yu J, Yang X
Fitoterapia 2025 Apr;182:106469
Fitoterapia 2025 Apr;182:106469
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Tang CT, Wu Y, Tao Q, Zeng CY, Chen YX
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Min L, Huo F, Zhu Z, Din L, Zhang L, Xu Y, Xing X, Zhang P, Wang Q
Cellular signalling 2025 Apr;128:111649
Cellular signalling 2025 Apr;128:111649
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
Liu J, Liu X, Xie X, Si W, Zhang Y, Xue M, Peng X, Jiang M, Du S, Shao J, Mao Y, Zhang F, Hu Y
Journal of cellular biochemistry 2025 Apr;126(4):e70031
Journal of cellular biochemistry 2025 Apr;126(4):e70031
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
3-D Sustained-Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells.
Luo L, Zhang S, Gong J, Zhang J, Xie P, Yin J, Zhang M, Zhang C, Chen H, Liu Y, Ni B, Li C, Tian Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410151
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410151
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Fu Y, Zhu D, Chen X, Qu L, Guo M, Zhang S, Xu G, Chen Z, Li M, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
Ren J, Wu P, Liu M, Zhang X, Guo Z, Liu Y, Zhao R, Wang G, Duan S, Li H
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway.
Su S, Wu L, Huang C, He C, Wang L, Li W, Liu W, Liu L
Discover oncology 2025 Apr 9;16(1):499
Discover oncology 2025 Apr 9;16(1):499
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Apolipoprotein M delays the development of atherosclerosis by regulating autophagy and mitochondrial function.
Shi Y, Yao S, Jiang B, Zhang J, Cao M, Wu J, Zheng L, Xu N, Zhang X, Shui G, Luo G
Cardiovascular diagnosis and therapy 2025 Apr 30;15(2):423-440
Cardiovascular diagnosis and therapy 2025 Apr 30;15(2):423-440
Exploring the Molecular Mechanism of 1,25(OH)(2)D(3) Reversal of Sorafenib Resistance in Hepatocellular Carcinoma Based on Network Pharmacology and Experimental Validation.
Long Z, Wu X, Luo T, Chen X, Huang J, Zhang S
Current issues in molecular biology 2025 Apr 29;47(5)
Current issues in molecular biology 2025 Apr 29;47(5)
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
Tu WC, He YK, Wang DW, Ming SX, Zhao Y
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
LncRNA HITT inhibits autophagy by attenuating ATG12-ATG5-ATG16L1 complex formation.
Liu H, Wang X, Li B, Xiang Z, Zhao Y, Lu M, Lin Q, Zheng S, Guan T, Zhang Y, Hu Y
Cancer letters 2025 Apr 28;616:217532
Cancer letters 2025 Apr 28;616:217532
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Guo J, Hu JP, Liu M, Chen Y, Zhang S, Guan S
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse.
Drago-Garcia D, Giri S, Chatterjee R, Simoni-Nieves A, Abedrabbo M, Genna A, Rios MLU, Lindzen M, Sekar A, Gupta N, Aharoni N, Bhandari T, Mayalagu A, Schwarzmüller L, Tarade N, Zhu R, Mohan-Raju HR, Karatekin F, Roncato F, Eyal-Lubling Y, Keidar T, Nof Y, Belugali Nataraj N, Bernshtein KS, Wagner B, Nair NU, Sanghvi N, Alon R, Seger R, Pikarsky E, Donzelli S, Blandino G, Wiemann S, Lev S, Prywes R, Barkan D, Rueda OM, Caldas C, Ruppin E, Shiloh Y, Dahlhoff M, Yarden Y
Science signaling 2025 Apr 22;18(883):eado3473
Science signaling 2025 Apr 22;18(883):eado3473
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Zhou W, Wang J, Ding L, Cai R, Cheng J, Liang P, Zhu Y, Zhang Z
Scientific reports 2025 Apr 21;15(1):13805
Scientific reports 2025 Apr 21;15(1):13805
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
He J, Yin L, Yuan Q, Su X, Shen Y, Deng Z
World journal of surgical oncology 2025 Apr 2;23(1):115
World journal of surgical oncology 2025 Apr 2;23(1):115
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
Wang F, Amona FM, Pang Y, Zhang Q, Liang Y, Chen X, Ke Y, Chen J, Song C, Wang Y, Li Z, Zhang C, Fang X, Chen X
Journal of virology 2025 Apr 15;99(4):e0158524
Journal of virology 2025 Apr 15;99(4):e0158524
3,4-Dimethoxychalcone alleviates limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and antioxidative response.
Qiu YH, Zhang YH, Wu ZC, Huang JY, Chen BC, Xiao J, Chen FF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70496
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70496
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein.
Xiao ZW, Zeng YC, Ji LT, Yuan JT, Li L
World journal of gastrointestinal oncology 2025 Apr 15;17(4):103843
World journal of gastrointestinal oncology 2025 Apr 15;17(4):103843
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136
Respiratory research 2025 Apr 12;26(1):136
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
USP18 Antagonizes Pyroptosis by Facilitating Selective Autophagic Degradation of Gasdermin D.
Wang L, Li M, Lian G, Yang S, Wu Y, Cui J
Research (Washington, D.C.) 2024;7:0380
Research (Washington, D.C.) 2024;7:0380
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
Zhu P, Wu Z, Yang Z, Tang T, Liao Y, Zhao W, Huang Y, Chen T, Li J, Nong C, Wu Z, Hu G, Liu Y, Chen Y
Research (Washington, D.C.) 2024;7:0344
Research (Washington, D.C.) 2024;7:0344
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Zheng B, Sun X, Zhang L, Qu G, Ren C, Yan P, Zhou C, Yue B
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Leukemia Inhibitory Factor Protects against Degeneration of Cone Photoreceptors Caused by RPE65 Deficiency.
Dong S, Zhen F, Zou T, Zhou Y, Wu J, Wang T, Zhang H
Current medicinal chemistry 2024;31(25):4022-4033
Current medicinal chemistry 2024;31(25):4022-4033
Method to Purify Phase-Separated p62 Bodies Using Fluorescence-Activated Particle Sorting.
Takada S, Komatsu M, Morishita H
Methods in molecular biology (Clifton, N.J.) 2024;2845:191-196
Methods in molecular biology (Clifton, N.J.) 2024;2845:191-196
Evidence for the potential role of m6A modification in regulating autophagy in models of amyotrophic lateral sclerosis.
An D, Han J, Fang P, Bu Y, Ji G, Liu M, Deng J, Song X
CytoJournal 2024;21:33
CytoJournal 2024;21:33
The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels.
Zhao G, Lyu J, Huang X, Huang G, Chen F, Wei Y, Wang S, Xia J, Chen J, Shi J
Archives of medical science : AMS 2024;20(5):1680-1694
Archives of medical science : AMS 2024;20(5):1680-1694
The PI3K/Akt-Nrf2 Signaling Pathway and Mitophagy Synergistically Mediate Hydroxytyrosol to Alleviate Intestinal Oxidative Damage.
Wen X, Tang S, Wan F, Zhong R, Chen L, Zhang H
International journal of biological sciences 2024;20(11):4258-4276
International journal of biological sciences 2024;20(11):4258-4276
Zinc Oxide Nanoparticles Exacerbate Epileptic Seizures by Modulating the TLR4-Autophagy Axis.
Ke P, Liu J, Chen C, Luo S, Gu H, Gu J, Liu Y, Ma Y, Meng Y, Hu L, Tian X, Xiao F
International journal of nanomedicine 2024;19:2025-2038
International journal of nanomedicine 2024;19:2025-2038
Overexpression of TRPV1 activates autophagy in human lens epithelial cells under hyperosmotic stress through Ca(2+)-dependent AMPK/mTOR pathway.
Huang LH, Lyu J, Chen S, Liang TY, Rao YQ, Fei P, Li J, Jin HY, Zhao PQ
International journal of ophthalmology 2024;17(3):420-434
International journal of ophthalmology 2024;17(3):420-434
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Dong J, Liu M, Bian Y, Zhang W, Yuan C, Wang D, Zhou Z, Li Y, Shi Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Li Y, Wu T, Li H, Liu M, Xu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Liu W, Li Y, An Y, Zhao R, Wei C, Ren X, He H
Journal of inflammation research 2024;17:2271-2284
Journal of inflammation research 2024;17:2271-2284
IRGM Deficiency Exacerbates Sepsis-Induced Acute Lung Injury by Inhibiting Autophagy Through the AKT/mTOR Signaling Pathway.
Guo N, Xia Y, He N, Cheng H, Zhang L, Liu J
Journal of inflammation research 2024;17:10255-10272
Journal of inflammation research 2024;17:10255-10272
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
Gao P, Chen A, Tian H, Wang F, Wang N, Ge K, Lian C, Wang F, Zhang Q
Journal of Cancer 2024;15(13):4313-4327
Journal of Cancer 2024;15(13):4313-4327
JiangyaTongluo decoction ameliorates tubulointerstitial fibrosis via regulating the SIRT1/PGC-1α/mitophagy axis in hypertensive nephropathy.
Zhao Y, Jia Q, Hao G, Han L, Gao Y, Zhang X, Yan Z, Li B, Wu Y, Zhang B, Li Y, Qin J
Frontiers in pharmacology 2024;15:1491315
Frontiers in pharmacology 2024;15:1491315
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717
Frontiers in pharmacology 2024;15:1393717
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
Wu S, Liu H, Yi J, Xu M, Jiang J, Tao J, Wu B
Gastroenterology report 2024;12:goae084
Gastroenterology report 2024;12:goae084
HSP90B1 regulates autophagy via PI3K/AKT/mTOR signaling, mediating HNSC biological behaviors.
Li C, Lin X, Su J
PeerJ 2024;12:e17028
PeerJ 2024;12:e17028
EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy.
Cai W, Xiao Y, Yan J, Peng H, Tu C
Frontiers in cell and developmental biology 2024;12:1489774
Frontiers in cell and developmental biology 2024;12:1489774
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Cilenti L, Di Gregorio J, Mahar R, Liu F, Ambivero CT, Periasamy M, Merritt ME, Zervos AS
Frontiers in molecular biosciences 2024;11:1397565
Frontiers in molecular biosciences 2024;11:1397565
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Wang W, Gong Z, Wang Y, Zhao Y, Lu Y, Sun R, Zhang H, Shang J, Zhang J
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
Enhancing Rab7 Activity by Inhibiting TBC1D5 Expression Improves Mitophagy in Alzheimer's Disease Models.
Liang X, Wang Y, Li S, Fan J, Zhou F, Li X, Li S, Li Y
Journal of Alzheimer's disease : JAD 2024;100(1):279-296
Journal of Alzheimer's disease : JAD 2024;100(1):279-296
IGF2BP2 modulates autophagy and serves as a prognostic marker in glioma.
Li N, Deng L, Zhang Y, Tang X, Lei B, Zhang Q
Ibrain 2024 Spring;10(1):19-33
Ibrain 2024 Spring;10(1):19-33
ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.
Cao J, Cao F, Wang C, Jiao Z, You Y, Wang X, Zhao W
Neoplasia (New York, N.Y.) 2024 Sep;55:101015
Neoplasia (New York, N.Y.) 2024 Sep;55:101015
ent-8(14),15-Pimaradiene-2β,19-diol, a diterpene from Aleuritopteris albofusca, inhibits growth and induces protective autophagy in hepatocellular carcinoma cells.
Zhang Y, Liu Z, Wang F, Liu J, Zhang Y, Cao J, Huang G, Ma L
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6867-6878
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6867-6878
Urolithin A exerts anti-tumor effects on gastric cancer via activating autophagy-Hippo axis and modulating the gut microbiota.
Qiao Y, Xia Q, Cao X, Xu J, Qiao Z, Wu L, Chen Z, Yang L, Lu X
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6633-6645
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6633-6645
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Zhou X, Wang M, Sun M, Yao N
Molecular medicine reports 2024 Sep;30(3)
Molecular medicine reports 2024 Sep;30(3)
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
Wen C, Jiang Y, Chen W, Xu Y, Chen G, Zhou Q, Liu Q, Jiang H, Liu Y, Cao X, Yao Y, Zhang R, Qiu Z, Liu S
Experimental and therapeutic medicine 2024 Sep;28(3):349
Experimental and therapeutic medicine 2024 Sep;28(3):349
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Jiang Y, Liu B, Fu L, Li F
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
The Role of BNIP3 and Blocked Autophagy Flux in Arsenic-Induced Oxidative Stress-Induced Liver Injury in Rats.
Zhi H, Bi D, Zheng D, Lu Q, Wang H, Wang Y, Lv Y, Lou D, Hu Y
Biological trace element research 2024 Sep;202(9):4054-4064
Biological trace element research 2024 Sep;202(9):4054-4064
FoxO1 silencing in Atp7b(-/-) neural stem cells attenuates high copper-induced apoptosis via regulation of autophagy.
Zhang Y, Wang M, Tang L, Yang W, Zhang J
Journal of neurochemistry 2024 Sep;168(9):2762-2774
Journal of neurochemistry 2024 Sep;168(9):2762-2774
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
The role of DNA damage response in human embryonic stem cells exposed to atmospheric oxygen tension: Implications for embryo development and differentiation.
Zhou Y, Ye F, Zhang L, Kang Q, Luo Y, Jiang N, Lou L, Mao Y, Wang L, Jin F
Reproductive toxicology (Elmsford, N.Y.) 2024 Sep;128:108648
Reproductive toxicology (Elmsford, N.Y.) 2024 Sep;128:108648
3-Hydroxy-3-methylglutaryl-CoA synthase 2 facilitates erectile dysfunction via inhibiting autophagy by enhancing the mammalian target of rapamycin pathway in type 1 diabetic mellitus rats.
Dai Z, Zeng Y, Tan X, Zhou T, Li X, Deng Q
Andrology 2024 Sep;12(6):1449-1462
Andrology 2024 Sep;12(6):1449-1462
Autophagy Deficiency Induced by SAT1 Potentiates Tumor Progression in Triple-Negative Breast Cancer.
Tian W, Zhu L, Luo Y, Tang Y, Tan Q, Zou Y, Chen K, Deng X, Tang H, Li H, Cai M, Xie X, Ye F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2309903
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2309903
Acteoside delays the fibrosis process of diabetic nephropathy by anti-oxidation and regulating the autophagy-lysosome pathway.
Zhou M, Zhang S, Bai X, Cai Y, Zhang Z, Zhang P, Xue C, Zheng H, Sun Q, Han D, Lou L, Wang Y, Liu W
European journal of pharmacology 2024 Sep 5;978:176715
European journal of pharmacology 2024 Sep 5;978:176715
Acid sphingomyelinase inhibition induces cerebral angiogenesis post-ischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism.
Mohamud Yusuf A, Borbor M, Hussner T, Weghs C, Kaltwasser B, Pillath-Eilers M, Walkenfort B, Kolesnick R, Gulbins E, Hermann DM, Brockmeier U
Cell death & disease 2024 Sep 4;15(9):650
Cell death & disease 2024 Sep 4;15(9):650
LncRNA MIAT suppresses inflammation in LPS-induced J774A.1 macrophages by promoting autophagy through miR-30a-5p/SOCS1 axi.
Sun L, Yang K, Wang L, Wu S, Wen D, Wang J
Scientific reports 2024 Sep 30;14(1):22608
Scientific reports 2024 Sep 30;14(1):22608
Isorhapontigenin delays senescence and matrix degradation of nucleus pulposus cells via PI3K/AKT/mTOR-mediated autophagy pathway in vitro and alleviates intervertebral disc degeneration in vivo.
Wang Z, Ma J, Sun Y, Jin Z, Zheng R, Li Y, Yu H, Ye H, Wu Y, Ge X, Chen Z
International immunopharmacology 2024 Sep 30;139:112717
International immunopharmacology 2024 Sep 30;139:112717
Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer.
Xue W, Xu C, Zhang K, Cui L, Huang X, Nan Y, Ju D, Chang X, Zhang X
Cell death discovery 2024 Sep 3;10(1):393
Cell death discovery 2024 Sep 3;10(1):393
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.
Zhao S, Sun J, Chang Q, Pang S, Zhang N, Fan Y, Liu J
Cancer cell international 2024 Sep 28;24(1):327
Cancer cell international 2024 Sep 28;24(1):327
Autophagy defects at weaning impair complement-dependent synaptic pruning and induce behavior deficits.
Su X, Wang G, Liu S, Li J, Shao M, Yang Y, Song M, Han Y, Li W, Lv L
Journal of neuroinflammation 2024 Sep 27;21(1):239
Journal of neuroinflammation 2024 Sep 27;21(1):239
Exposure to Succinate Leads to Steatosis in Non-Obese Non-Alcoholic Fatty Liver Disease by Inhibiting AMPK/PPARα/FGF21-Dependent Fatty Acid Oxidation.
Yang H, Ran S, Zhou Y, Shi Q, Yu J, Wang W, Sun C, Li D, Hu Y, Pan C, Yuan Q, Zhen Y, Liu Q, Song L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21052-21064
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21052-21064
Schisandrin B attenuates bleomycin-induced pulmonary fibrosis in mice through AKT-mTOR pathway.
Yang J, Zhou D, Hu J, Yang DH, Cai Y, Lu Q
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2024 Sep 24;41(3):e2024034
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2024 Sep 24;41(3):e2024034
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Chen D, Wu L, Liu X, Wang Q, Gui S, Bao L, Wang Z, He X, Zhao Y, Zhou J, Xie Y
Scientific reports 2024 Sep 17;14(1):21648
Scientific reports 2024 Sep 17;14(1):21648
Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study.
Guo R, Liu H, Su R, Mao Q, Zhao M, Zhang H, Mu J, Zhao N, Wang Y, Hao Y
Journal of ethnopharmacology 2024 Sep 15;331:118159
Journal of ethnopharmacology 2024 Sep 15;331:118159
Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy.
Ying W, Yunqi Z, Deji L, Jian K, Fusheng Q
Theriogenology 2024 Sep 15;226:263-276
Theriogenology 2024 Sep 15;226:263-276
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma.
Li Y, Wang F, Geng Z, He T, Song Y, Wu J, Wang B
Cell & bioscience 2024 Sep 10;14(1):116
Cell & bioscience 2024 Sep 10;14(1):116
SS-31 mitigates oxidative stress and restores mitochondrial function in cigarette smoke-damaged oral epithelial cells via PINK1-mediated mitophagy.
Ye P, Liu H, Qin Y, Li Z, Huang Z, Bu X, Peng Q, Duan N, Wang W, Wang X
Chemico-biological interactions 2024 Sep 1;400:111166
Chemico-biological interactions 2024 Sep 1;400:111166
Lubricin-Inspired Nanozymes Reconstruct Cartilage Lubrication System with an "In-Out" Strategy.
Du C, Chen Z, Liu S, Liu J, Zhan J, Zou J, Liao J, Huang W, Lei Y
Small methods 2024 Oct;8(10):e2400757
Small methods 2024 Oct;8(10):e2400757
Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction.
Ren YL, Jiang Z, Wang JY, He Q, Li SX, Gu XJ, Qi YR, Zhang M, Yang WJ, Cao B, Li JY, Wang Y, Chen YP
Molecular neurobiology 2024 Oct;61(10):7968-7988
Molecular neurobiology 2024 Oct;61(10):7968-7988
Placental growth factor alleviates hyperglycemia-induced trophoblast pyroptosis by regulating mitophagy.
Tao J, Rao Y, Wang J, Tan S, Zhao J, Cao Z, He L, Meng J, Wu P, Wang Z
The journal of obstetrics and gynaecology research 2024 Oct;50(10):1813-1829
The journal of obstetrics and gynaecology research 2024 Oct;50(10):1813-1829
Electroacupuncture ameliorates senile osteoporosis by promoting bone remodeling and regulating autophagy.
Liu J, Zhou J, Wang J, Huang X, Qu M, Liao Y, Sun G, Zhong P, Tan J, Sun Z
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Oct;42(5):260-267
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2024 Oct;42(5):260-267
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Shen Z, Zhao L, Yoo SA, Lin Z, Zhang Y, Yang W, Piao J
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Sparassis latifolia polysaccharide alleviated lipid metabolism abnormalities in kidney of lead-exposed mice by regulating oxidative stress-mediated inflammation and autophagy based on multi-omics.
Lu X, Wu S, Ai H, Wu R, Cheng Y, Yun S, Chang M, Liu J, Meng J, Cheng F, Feng C, Cao J
International journal of biological macromolecules 2024 Oct;278(Pt 1):134662
International journal of biological macromolecules 2024 Oct;278(Pt 1):134662
Truncation mutations of CRYGD gene in congenital cataracts cause protein aggregation by disrupting the structural stability of γD-crystallin.
Lin N, Song H, Zhang Y, Chen F, Xu J, Wu W, Tian Q, Luo C, Yao K, Hu L, Chen X
International journal of biological macromolecules 2024 Oct;277(Pt 2):134292
International journal of biological macromolecules 2024 Oct;277(Pt 2):134292
RNF144B negatively regulates antiviral immunity by targeting MDA5 for autophagic degradation.
Li G, Zhang J, Zhao Z, Wang J, Li J, Xu W, Cui Z, Sun P, Yuan H, Wang T, Li K, Bai X, Ma X, Li P, Fu Y, Cao Y, Bao H, Li D, Liu Z, Zhu N, Tang L, Lu Z
EMBO reports 2024 Oct;25(10):4594-4624
EMBO reports 2024 Oct;25(10):4594-4624
S100A9-TLR4 axis aggravates dry eye through the blockage of autophagy.
Liang L, Yang X, Zeng H, Liao K, Zhang R, Wang B, Yuan J
Experimental eye research 2024 Oct;247:110052
Experimental eye research 2024 Oct;247:110052
PLK2-mediated phosphorylation of SQSTM1 S349 promotes aggregation of polyubiquitinated proteins upon proteasomal dysfunction.
Chen YD, Lin XP, Ruan ZL, Li M, Yi XM, Zhang X, Li S, Shu HB
Autophagy 2024 Oct;20(10):2221-2237
Autophagy 2024 Oct;20(10):2221-2237
TMX2 potentiates cell viability of hepatocellular carcinoma by promoting autophagy and mitophagy.
Zhang W, Tang Y, Yang P, Chen Y, Xu Z, Qi C, Huang H, Liu R, Qin H, Ke H, Huang C, Xu F, Pang P, Zhao Z, Shan H, Xiao F
Autophagy 2024 Oct;20(10):2146-2163
Autophagy 2024 Oct;20(10):2146-2163
Bunyavirus SFTSV NSs utilizes autophagy to escape the antiviral innate immune response.
Li ZM, Duan SH, Yu TM, Li B, Zhang WK, Zhou CM, Yu XJ
Autophagy 2024 Oct;20(10):2133-2145
Autophagy 2024 Oct;20(10):2133-2145
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS, ER stress, and blocked autophagy.
Ji Y, Li C, Wan S, Dong Z, Liu C, Guo L, Shi S, Ci M, Xu M, Li Q, Hu H, Cui H, Liu Y
Journal of pharmaceutical analysis 2024 Oct;14(10):101036
Journal of pharmaceutical analysis 2024 Oct;14(10):101036
Blocking ACSL6 Compromises Autophagy via FLI1-Mediated Downregulation of COLs to Radiosensitize Lung Cancer.
Ding W, Bao S, Zhao Q, Hao W, Fang K, Xiao Y, Lin X, Zhao Z, Xu X, Cui X, Yang X, Yao L, Jin H, Zhang K, Guo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(40):e2403202
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(40):e2403202
The Hemagglutinin of Influenza A Virus Induces Ferroptosis to Facilitate Viral Replication.
Ouyang A, Chen T, Feng Y, Zou J, Tu S, Jiang M, Sun H, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2404365
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2404365
A20 Alleviates the Inflammatory Response in Bovine Endometrial Epithelial Cells by Promoting Autophagy.
Dong J, Ji B, Jiang Y, Fei F, Guo L, Liu K, Cui L, Meng X, Li J, Wang H
Animals : an open access journal from MDPI 2024 Oct 6;14(19)
Animals : an open access journal from MDPI 2024 Oct 6;14(19)
Overcoming multi-drug resistance in SCLC: a synergistic approach with venetoclax and hydroxychloroquine targeting the lncRNA LYPLAL1-DT/BCL2/BECN1 pathway.
Li S, Lv J, Li Z, Zhang Q, Lu J, Huo X, Guo M, Liu X, Li C, Wang J, Shi H, Deng L, Chen Z, Du X
Molecular cancer 2024 Oct 31;23(1):243
Molecular cancer 2024 Oct 31;23(1):243
MiR-155-5p regulates autophagy and apoptosis of glioma cells through RICTOR.
Guo Z, Tian JJ, Wang Y, Jiang L, Chen Y, Dai HJ, Wang L, Zhang Y
Translational cancer research 2024 Oct 31;13(10):5509-5521
Translational cancer research 2024 Oct 31;13(10):5509-5521
Quercetin activates autophagy in the distal ischemic area of random skin flaps through Beclin1 to enhance the adaptability to energy deficiency.
Zheng X, Wang Y, Gong X, Chen W, Zheng W, Chen T
Heliyon 2024 Oct 30;10(20):e38181
Heliyon 2024 Oct 30;10(20):e38181
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Zheng S, Zhu J, Wang C, Wu Y, Sun S, Guo H, Chang Y, Ma R, Li G
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Potential role of host autophagy in Clonorchis sinensis infection.
Shang M, Gong Y, Luo H, Chen W, Wu Y, Hu B, Dong H, Li X
Parasitology research 2024 Oct 23;123(10):359
Parasitology research 2024 Oct 23;123(10):359
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Huang Y, Huang Y, Cai Z, Ferrari MW, Li C, Zhang T, Lyu G, Wang Z
Communications biology 2024 Oct 22;7(1):1371
Communications biology 2024 Oct 22;7(1):1371
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
Wang G, Zhao R, Guo Z, Cui H, Wang D, Ren J, Zhu S, Zhang K, Tang B, Zhang J, Li P, Duan S, Li H
Human cell 2024 Oct 22;38(1):4
Human cell 2024 Oct 22;38(1):4
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
Wang S, Cheng T, Chen X, Zeng C, Qin W, Xu Y
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Wang S, Li X, Wang T, Sun Z, Feng E, Jin Y
Communications biology 2024 Oct 15;7(1):1330
Communications biology 2024 Oct 15;7(1):1330
Black phosphorus nanosheets induce autophagy dysfunction by a size- and surface modification-related impairment of lysosomes in macrophages.
Deng S, Zhao Q, Liu D, Xiong Z, Zhang S, Zhang X, Wu F, Xing B
Ecotoxicology and environmental safety 2024 Oct 15;285:117073
Ecotoxicology and environmental safety 2024 Oct 15;285:117073
Silica nanoparticles cause ovarian dysfunction and fertility decrease in mice via oxidative stress-activated autophagy and apoptosis.
Liu W, Liu H, Zhang S, Hao H, Meng F, Ma W, Guo Z, Jiang S, Shang X
Ecotoxicology and environmental safety 2024 Oct 15;285:117049
Ecotoxicology and environmental safety 2024 Oct 15;285:117049
Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer's disease.
Zhang Z, Li M, Li X, Feng Z, Luo G, Wang Y, Gao X
Journal of neuroinflammation 2024 Oct 15;21(1):261
Journal of neuroinflammation 2024 Oct 15;21(1):261
Tumor-associated macrophages/C-X-C motif chemokine ligand 1 promotes breast cancer autophagy-mediated chemoresistance via IGF1R/STAT3/HMGB1 signaling.
Yang B, Li G, Wang S, Zheng Y, Zhang J, Pan B, Wang N, Wang Z
Cell death & disease 2024 Oct 11;15(10):743
Cell death & disease 2024 Oct 11;15(10):743
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
Chen Y, Zhang M, Liu Z, Zhang N, Wang Q
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
Continuous Theta Burst Stimulation Inhibits Oxidative Stress-Induced Inflammation and Autophagy in Hippocampal Neurons by Activating Glutathione Synthesis Pathway, Improving Cognitive Impairment in Sleep-Deprived Mice.
Zhang Y, Zhang C, Dai Q, Ma R
Neuromolecular medicine 2024 Oct 10;26(1):40
Neuromolecular medicine 2024 Oct 10;26(1):40
GL-V9 Promotes Autophagy-Mediated YAP1 Degradation and Activates Mitochondrial Apoptosis in PDAC Cells.
Liu H, Lin Z, Guo Y, Zhou Y, Li W
Pharmaceuticals (Basel, Switzerland) 2024 Oct 10;17(10)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 10;17(10)
The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by enhancing migration of Schwann cells.
Tang W, Yin X, Liu K, Shao T, Gao Q, Shen H, Zhong X, Zhang Z
Experimental cell research 2024 Oct 1;442(2):114261
Experimental cell research 2024 Oct 1;442(2):114261
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Liu C, Wu C, Zhang S, Lv Z
Experimental gerontology 2024 Oct 1;195:112528
Experimental gerontology 2024 Oct 1;195:112528
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.
Li D, Xiong Y, Li M, Long L, Zhang Y, Yan H, Xiang H
Archives of biochemistry and biophysics 2024 Nov;761:110149
Archives of biochemistry and biophysics 2024 Nov;761:110149
Hexavalent chromium reduces testosterone levels by impairing lipophagy and disrupting lipid metabolism homeostasis: Based on a metabolomic analysis.
Xue Q, Zhang L, Wang R, Xu J, Wang C, Gao S, Fang X, Meng C, Lu R, Guo L
Toxicology 2024 Nov;508:153908
Toxicology 2024 Nov;508:153908
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
Zhuge R, Zhang L, Xue Q, Wang R, Xu J, Wang C, Meng C, Lu R, Yin F, Guo L
Toxicology and applied pharmacology 2024 Nov;492:117139
Toxicology and applied pharmacology 2024 Nov;492:117139
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti-AD compound, screened via network proximity and gene enrichment analyses.
Zhao J, Guo P, Fang J, Wang C, Yan C, Bai Y, Wang Z, Du G, Liu A
Phytotherapy research : PTR 2024 Nov;38(11):5474-5489
Phytotherapy research : PTR 2024 Nov;38(11):5474-5489
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
Zhu Z, Song J, Zhang C, Zhang J, Shan Z
Oral diseases 2024 Nov;30(8):5050-5061
Oral diseases 2024 Nov;30(8):5050-5061
High levels of mitochondrial dynamics, autophagy, and apoptosis contribute to stable testicular status in hibernating Daurian ground squirrels.
Wang Z, Wang MD, Wang XC, Chen L, Li LF, Jiang LN, Xu JH, Kai Dang
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2024 Nov;297:111705
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2024 Nov;297:111705
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Lu L, Chen J, Jiang H, Li N, Li X, Liu Y, Zong C
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
(-)-Epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation.
Shao Y, Zhang Y, Zou S, Wang J, Li X, Qin M, Sun L, Yin W, Chang X, Wang S, Han X, Wu T, Chen F
Autophagy 2024 Nov;20(11):2460-2477
Autophagy 2024 Nov;20(11):2460-2477
Angiopoietin 1 Relieves Osteolysis by Promoting Macrophage Mitophagy Through the TBK1-SQSTM1 Pathway to Inhibit AIM2 Inflammasome-Mediated Pyroptosis.
Yin J, Lai P, Zhu L, Ma J
Applied biochemistry and biotechnology 2024 Nov;196(11):7908-7927
Applied biochemistry and biotechnology 2024 Nov;196(11):7908-7927
Expediting the development of robust 5-FU-resistant colorectal cancer models using innovative combined in vivo and in vitro strategies.
Shao M, Gao Y, Xu X, Shi J, Wang Z, Du J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117576
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117576
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer.
Xu C, Huang X, Hu Q, Xue W, Zhou K, Li X, Nan Y, Ju D, Wang Z, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117550
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117550
Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy.
Li D, Yuan X, Ma J, Lu T, Zhang J, Liu H, Zhang G, Wang Y, Liu X, Xie Q, Zhou L, Xu M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117510
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117510
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
Ding L, Guo H, Zhang J, Zheng M, Zhang W, Wang L, Du Q, Zhou C, Xu Y, Wu H, He Q, Yang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Cai X, Zhang H, Kong S, Xu W, Zheng J, Wang N, He S, Li S, Shen Y, Wang K, Zhang Z, Cai H, Ma F, Bai S, Zhu F, Xiao F, Wang F
Cell death & disease 2024 Nov 8;15(11):806
Cell death & disease 2024 Nov 8;15(11):806
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity.
Huang Y, Luo G, Peng K, Song Y, Wang Y, Zhang H, Li J, Qiu X, Pu M, Liu X, Peng C, Neculai D, Sun Q, Zhou T, Huang P, Liu W
The Journal of cell biology 2024 Nov 4;223(11)
The Journal of cell biology 2024 Nov 4;223(11)
Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation.
Lv X, Nie C, Shi Y, Qiao Q, Gao J, Zou Y, Yang J, Chen L, Hou X
Lipids in health and disease 2024 Nov 28;23(1):395
Lipids in health and disease 2024 Nov 28;23(1):395
Trehalose Alleviates D-Galactose-Induced Aging-Related Granulosa Cell Death in Ovaries.
Xi H, Chen X, Liang K, Wang X, Jiang F, Li Y, Niu D
International journal of molecular sciences 2024 Nov 25;25(23)
International journal of molecular sciences 2024 Nov 25;25(23)
Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy.
Ren J, Pei Q, Dong H, Wei X, Li L, Duan H, Zhang G, Zhang A
Journal of virology 2024 Nov 19;98(11):e0143724
Journal of virology 2024 Nov 19;98(11):e0143724
Cremastrae Pseudobulbus Pleiones Pseudobulbus (CPPP) Against Non-Small-Cell Lung Cancer: Elucidating Effective Ingredients and Mechanism of Action.
Cao Y, Hao Z, Liu M, Xue J, Wang Y, Wang Y, Li J, Lu Y, Wang C, Shi J
Pharmaceuticals (Basel, Switzerland) 2024 Nov 11;17(11)
Pharmaceuticals (Basel, Switzerland) 2024 Nov 11;17(11)
LncRNA AGAP2-AS1 stabilizes ATG9A to promote autophagy in endothelial cells - Implications for burn wound healing.
Guo L, Zhang P, Zhang M, Liang P, Zhou S
Experimental cell research 2024 Nov 1;443(1):114310
Experimental cell research 2024 Nov 1;443(1):114310
Soybean isoflavones protect dopaminergic neurons from atrazine damage by inhibiting VPS13A to increase autophagy.
Li P, Song W, Xu N, Wang Z, Pang H, Wang D
Ecotoxicology and environmental safety 2024 Nov 1;286:117225
Ecotoxicology and environmental safety 2024 Nov 1;286:117225
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Shi M, Guo Y, Xu J, Yan L, Li X, Liu R, Feng Y, Zhang Y, Zhao Y, Zhang C, Du K, Li M, Zhang Y, Zhang J, Li Z, Ren D, Liu P
Free radical biology & medicine 2024 Nov 1;224:770-784
Free radical biology & medicine 2024 Nov 1;224:770-784
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
Jiang Y, Xu S, Guo M, Lu Z, Wei X, An F, Xin X
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
USP26 promotes colorectal cancer tumorigenesis by restraining PRKN-mediated mitophagy.
Wu Q, Wang Z, Chen S, She X, Zhu S, Li P, Liu L, Zhao C, Li K, Liu A, Huang C, Chen Y, Hu F, Wang G, Hu J
Oncogene 2024 May;43(21):1581-1593
Oncogene 2024 May;43(21):1581-1593
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
Shen J, Jin J, Huang J, Guo Y, Qian Q
Experimental dermatology 2024 May;33(5):e15094
Experimental dermatology 2024 May;33(5):e15094
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner.
Xu W, Hua Z, Wang Y, Tang W, Ou W, Liu F, Yang Y, Ding W, Wang Z, Cui L, Ge W, Gu Y, Wang X, Chen Y, Liu CY, Du P
Cell death and differentiation 2024 May;31(5):618-634
Cell death and differentiation 2024 May;31(5):618-634
Tau regulates Arc stability in neuronal dendrites via a proteasome-sensitive but ubiquitin-independent pathway.
Yakout DW, Shroff A, Wei W, Thaker V, Allen ZD, Sajish M, Nazarko TY, Mabb AM
The Journal of biological chemistry 2024 May;300(5):107237
The Journal of biological chemistry 2024 May;300(5):107237
Nicotinamide ribose ameliorates myocardial ischemia/reperfusion injury by regulating autophagy and regulating oxidative stress.
Yuan C, Yang H, Lan W, Yang J, Tang Y
Experimental and therapeutic medicine 2024 May;27(5):187
Experimental and therapeutic medicine 2024 May;27(5):187
NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway.
Ren S, Chen Y, Wang Q, Song L, Xin Z, Shi M, Liu X
Pathology, research and practice 2024 May;257:155323
Pathology, research and practice 2024 May;257:155323
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Zhang Z, Kang Z, Deng K, Li J, Liu Z, Huang X, Wang F, Fan Y
Journal of cellular physiology 2024 May;239(5):e31226
Journal of cellular physiology 2024 May;239(5):e31226
UBC9-mediated SUMOylation of Lamin B1 enhances DNA-damage-induced nuclear DNA leakage and autophagy after spinal cord injury.
Fan YP, Lou JS, Jin MR, Zhou CH, Shen HH, Fu CY, Mao XJ, Chen YY, Zhong JJ, Wang LL, Wu JS
Journal of cellular physiology 2024 May;239(5):e31213
Journal of cellular physiology 2024 May;239(5):e31213
Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy.
Xu Y, Qian C, Wang Q, Song L, He Z, Liu W, Wan W
Autophagy 2024 May;20(5):1134-1146
Autophagy 2024 May;20(5):1134-1146
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Wang Q, Liu C, Chen M, Zhao J, Wang D, Gao P, Zhang C, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η.
Hu T, Hu FJ, Huang H, Zhang ZY, Qiao YM, Huang WX, Wang YC, Tang XY, Lai SQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116542
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.
Xu M, Zhong W, Yang C, Liu M, Yuan X, Lu T, Li D, Zhang G, Liu H, Zeng Y, Yang X, Zhou Y, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155392
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J
Research square 2024 May 30;
Research square 2024 May 30;
Label-Free Three-Dimensional Morphological Characterization of Cell Death Using Holographic Tomography.
Huang CH, Lai YJ, Chen LN, Hung YH, Tu HY, Cheng CJ
Sensors (Basel, Switzerland) 2024 May 26;24(11)
Sensors (Basel, Switzerland) 2024 May 26;24(11)
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias.
Ohiri JC, Dellefave-Castillo L, Tomar G, Wilsbacher L, Choudhury L, Barefield DY, Fullenkamp D, Gacita AM, Monroe TO, Pesce L, Blancard M, Vaught L, George AL Jr, Demonbreun AR, Puckelwartz MJ, McNally EM
Journal of the American Heart Association 2024 May 21;13(10):e030467
Journal of the American Heart Association 2024 May 21;13(10):e030467
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
Chen S, Yang Y, Zheng Z, Zhang M, Chen X, Xiao N, Liu H
Cell death discovery 2024 May 18;10(1):238
Cell death discovery 2024 May 18;10(1):238
AMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy.
Liu M, Wei X, Zheng Z, Xie E, Yu Q, Gao Y, Ma J, Yang L
Molecular medicine (Cambridge, Mass.) 2024 May 17;30(1):63
Molecular medicine (Cambridge, Mass.) 2024 May 17;30(1):63
Curdepsidone A Induces Intrinsic Apoptosis and Inhibits Protective Autophagy via the ROS/PI3K/AKT Signaling Pathway in HeLa Cells.
Xu S, Li Z, Xin X, An F
Marine drugs 2024 May 17;22(5)
Marine drugs 2024 May 17;22(5)
Exploring the neuroprotective role of artesunate in mouse models of anti-NMDAR encephalitis: insights from molecular mechanisms and transmission electron microscopy.
Liu J, Huang Y, Qian T, Chen J, Ding Y, Lai Z, Zhong X, Lai M, Zhang H, Wang Y, Wang H, Peng Y
Cell communication and signaling : CCS 2024 May 14;22(1):269
Cell communication and signaling : CCS 2024 May 14;22(1):269
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
Jiao K, Lai Z, Cheng Q, Yang Z, Liao W, Liao Y, Long H, Sun R, Lang T, Shao L, Deng C, She Y
Journal of ethnopharmacology 2024 May 10;325:117766
Journal of ethnopharmacology 2024 May 10;325:117766
Selenomethionine preconditioned mesenchymal stem cells derived extracellular vesicles exert enhanced therapeutic efficacy in intervertebral disc degeneration.
Ma S, Xue R, Zhu H, Han Y, Ji X, Zhang C, Wei N, Xu J, Li F
International immunopharmacology 2024 May 10;132:112028
International immunopharmacology 2024 May 10;132:112028
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
Autophagy activity is increased in the cumulus cells of women with poor ovarian response.
Zhu JR, Zhu WJ, Li T, Ou JP
Taiwanese journal of obstetrics & gynecology 2024 Mar;63(2):205-213
Taiwanese journal of obstetrics & gynecology 2024 Mar;63(2):205-213
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Weng AB, Deng MM, Liu XD, Wang HB, Lin Q
Iranian journal of public health 2024 Mar;53(3):614-624
Iranian journal of public health 2024 Mar;53(3):614-624
Selective degradation of PL2L60 by metabolic stresses‑induced autophagy suppresses multi‑cancer growth.
Sun L, Hui F, Tang GY, Shen HL, Cao XL, Gao JX, Li LF
Oncology reports 2024 Mar;51(3)
Oncology reports 2024 Mar;51(3)
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Li Z, Zhang F, Huang L, Deng J, Pan Y, Xu T, Liu J, Gao N, Duan R, Shao C, Wu C, Wang M, Lu L
Neurochemical research 2024 Mar;49(3):670-683
Neurochemical research 2024 Mar;49(3):670-683
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
Li Y, Yang J, Chen X, Hu H, Lan N, Zhao J, Zheng L
Biomaterials 2024 Mar;305:122449
Biomaterials 2024 Mar;305:122449
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitro.
Han Y, Wang C, Lu K, Dong X, Chang Z, Zhang R, Hou Q, Wang X, Xiao S, Liu H, Yang Z
Veterinary microbiology 2024 Mar;290:109972
Veterinary microbiology 2024 Mar;290:109972
CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction.
Wang H, Ye J, Peng Y, Ma W, Chen H, Sun H, Feng Z, He W, Li G, Chu S, Zhang Z, Chen N
Autophagy 2024 Mar;20(3):590-613
Autophagy 2024 Mar;20(3):590-613
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Wen T, Xie J, Ma L, Hao Z, Zhang W, Wu T, Li L
The American journal of pathology 2024 Mar;194(3):369-383
The American journal of pathology 2024 Mar;194(3):369-383
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Hu R, Wang XJ, Chen S, Huang Y, Yu J
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Kaempferol improves Pb-induced cognitive impairments via inhibiting autophagy.
Wang M, Xia Y, Ai S, Gu X, Wang HL
The Journal of nutritional biochemistry 2024 Mar;125:109556
The Journal of nutritional biochemistry 2024 Mar;125:109556
Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke.
Xie J, Zhang Y, Li B, Xi W, Wang Y, Li L, Liu C, Shen L, Han B, Kong Y, Yao H, Zhang Z
Journal of translational medicine 2024 Mar 7;22(1):248
Journal of translational medicine 2024 Mar 7;22(1):248
Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy.
Li Z, Zhang Y, Zhao B, Xue Q, Wang C, Wan S, Wang J, Chen X, Qi X
Veterinary research 2024 Mar 5;55(1):27
Veterinary research 2024 Mar 5;55(1):27
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
Liu ZD, Shi YH, Xu QC, Zhao GY, Zhu YQ, Li FX, Ma MJ, Ye JY, Huang XT, Wang XY, Xu X, Wang JQ, Zhao W, Yin XY
Cancer letters 2024 Mar 31;585:216640
Cancer letters 2024 Mar 31;585:216640
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
Wang X, Liu Z, Deng S, Zhou J, Li X, Huang J, Chen J, Ji C, Deng Y, Hu Y
International immunopharmacology 2024 Mar 30;130:111755
International immunopharmacology 2024 Mar 30;130:111755
ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis.
Zhang T, Zhu S, Huang GW
World journal of gastroenterology 2024 Mar 28;30(12):1764-1776
World journal of gastroenterology 2024 Mar 28;30(12):1764-1776
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Dong J, Wang B, Xiao Y, Liu J, Wang Q, Xiao H, Jin Y, Liu Z, Chen Z, Li Y, Fan S, Li Y, Cui M
Cell reports 2024 Mar 26;43(3):113846
Cell reports 2024 Mar 26;43(3):113846
Glucosylceramide accumulation in microglia triggers STING-dependent neuroinflammation and neurodegeneration in mice.
Wang R, Sun H, Cao Y, Zhang Z, Chen Y, Wang X, Liu L, Wu J, Xu H, Wu D, Mu C, Hao Z, Qin S, Ren H, Han J, Fang M, Wang G
Science signaling 2024 Mar 26;17(829):eadk8249
Science signaling 2024 Mar 26;17(829):eadk8249
Novel TFG mutation causes autosomal-dominant spastic paraplegia and defects in autophagy.
Xu L, Wang Y, Wang W, Zhang R, Zhao D, Yun Y, Liu F, Zhao Y, Yan C, Lin P
Journal of medical genetics 2024 Mar 21;61(4):325-331
Journal of medical genetics 2024 Mar 21;61(4):325-331
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway.
Wang DX, Bao SY, Song NN, Chen WZ, Ding XQ, Walker RJ, Fang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23436
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Wang W, Zhou C, Ma Z, Zeng L, Wang H, Cheng X, Zhang C, Xue Y, Yuan Y, Li J, Hu L, Huang J, Luo T, Zheng L
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Luo X, Zhang J, Guo C, Jiang N, Zhang F, Jiao Q, Xu K, Yang J, Qu G, Lv XB, Zhang Z
Gene 2024 Mar 10;898:148110
Gene 2024 Mar 10;898:148110
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
Yao W, Zhang Q, Zhao Y, Xu X, Zhang S, Wang X
Journal of ethnopharmacology 2024 Mar 1;321:117536
Journal of ethnopharmacology 2024 Mar 1;321:117536
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
Yang Y, Song B, Guo M, Gao J, Jiang L, Li Q, Liu Y, Cao J
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Li D, Zhou L, Liu Z, Zhang Z, Mao W, Shi W, Zhu M, Wang F, Wan Y
Theriogenology 2024 Mar 1;216:20-29
Theriogenology 2024 Mar 1;216:20-29
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Zhou C, Li D, He J, Luo T, Liu Y, Xue Y, Huang J, Zheng L, Li J
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.
Wang L, Zhuang J, Xue Z, Lu H, Zeng W, Zhang T
Journal of food science 2024 Jun;89(6):3858-3870
Journal of food science 2024 Jun;89(6):3858-3870
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Xu T, Zhao H, Li J, Fang X, Wu H, Hu W
JOR spine 2024 Jun;7(2):e1325
JOR spine 2024 Jun;7(2):e1325
CircUTRN24/miR-483-3p/IGF-1 Regulates Autophagy Mediated Liver Fibrosis in Biliary Atresia.
Liu D, Wu Z, Gao J, Mei Q, Zhang X, Wang B
Molecular biotechnology 2024 Jun;66(6):1424-1433
Molecular biotechnology 2024 Jun;66(6):1424-1433
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Lin JJ, Chen R, Yang LY, Gong M, Du MY, Mu SQ, Jiang ZA, Li HH, Yang Y, Wang XH, Wang SF, Liu KX, Cao SH, Wang ZY, Zhao AQ, Yang SY, Li C, Sun SG
Journal of advanced research 2024 Jun;60:93-110
Journal of advanced research 2024 Jun;60:93-110
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
Zeng X, Sun J, Li F, Peng L, Zhang C, Jiang X, Zha L, Rathinasabapathy A, Ren J, Yu Z, Wang L, Liu X
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Wang H, Liu X, Yan X, Du Y, Pu F, Ren J, Qu X
Biomaterials 2024 Jun;307:122523
Biomaterials 2024 Jun;307:122523
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3.
Shi X, Yao J, Huang Y, Wang Y, Jiang X, Wang Z, Zhang M, Zhang Y, Liu X
The Journal of biological chemistry 2024 Jun;300(6):107335
The Journal of biological chemistry 2024 Jun;300(6):107335
Identification critical host factors for Japanese encephalitis virus replication via CRISPR screening of human sgRNA library.
Liu LL, Yin YQ, Ma KX, Xing JC, Ren XX, Huang JY, Liao M, Qi WB, Huang LH
Veterinary microbiology 2024 Jun;293:110099
Veterinary microbiology 2024 Jun;293:110099
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
Qi W, Jin L, Huang S, Aikebaier A, Xue S, Wang Q, Chen Q, Lu Y, Ding C
Acta biomaterialia 2024 Jun;181:425-439
Acta biomaterialia 2024 Jun;181:425-439
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Li R, Geng H, Tan X, Wang J, Deng L
The Journal of nutrition 2024 Jun;154(6):1790-1802
The Journal of nutrition 2024 Jun;154(6):1790-1802
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Sheng X, Wang MM, Zhang GD, Su Y, Fang HB, Yu ZH, Su Z
Bioorganic chemistry 2024 Jun;147:107325
Bioorganic chemistry 2024 Jun;147:107325
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C
Journal of autoimmunity 2024 Jun;146:103214
Journal of autoimmunity 2024 Jun;146:103214
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.
Tan Y, Qiao J, Yang S, Liu H, Wang Q, Liu Q, Feng W, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140
CYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells.
Hao Z, Liu X, He H, Wei Z, Shu X, Wang J, Sun B, Zhou H, Wang J, Niu Y, Hu Z, Hu S, Liu Y, Fu Z
Molecular medicine (Cambridge, Mass.) 2024 Jun 7;30(1):79
Molecular medicine (Cambridge, Mass.) 2024 Jun 7;30(1):79
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Qi Z, Bai X, Wu L, Zhang P, Guo Z, Yu Y
Journal of translational medicine 2024 Jun 6;22(1):538
Journal of translational medicine 2024 Jun 6;22(1):538
Microbial metabolite sodium butyrate enhances the anti-tumor efficacy of 5-fluorouracil against colorectal cancer by modulating PINK1/Parkin signaling and intestinal flora.
Li Y, He P, Chen Y, Hu J, Deng B, Liu C, Yu B, Dong W
Scientific reports 2024 Jun 6;14(1):13063
Scientific reports 2024 Jun 6;14(1):13063
Hypoxia-inducible factor prolyl hydroxylase inhibitor alleviates heatstroke-induced acute kidney injury by activating BNIP3-mediated mitophagy.
Wang L, Song Y, Zhang P, Chen W, Xiao F, Zhou P, Yang X, Dai H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23723
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jun 30;38(12):e23723
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS-RAF1-MEK1/2-ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy.
Wu Y, Jia Q, Tang Q, Chen L, Deng H, He Y, Tang F
Cellular & molecular biology letters 2024 Jun 28;29(1):92
Cellular & molecular biology letters 2024 Jun 28;29(1):92
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Lei LM, Li FX, Lin X, Xu F, Shan SK, Guo B, Zheng MH, Tang KX, Wang Y, Xu QS, Ouyang WL, Duan JY, Wu YY, Cao YC, Zhou ZA, He SY, Wu YL, Chen X, Lin ZJ, Pan Y, Yuan LQ, Li ZH
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
Chen F
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
Myostatin regulates energy homeostasis through autocrine- and paracrine-mediated microenvironment communication.
Wang H, Guo S, Gao H, Ding J, Li H, Kong X, Zhang S, He M, Feng Y, Wu W, Xu K, Chen Y, Zhang H, Liu T, Kong X
The Journal of clinical investigation 2024 Jun 18;134(16)
The Journal of clinical investigation 2024 Jun 18;134(16)
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
Bai J, Feng Z, Chen Y, Li Y, Zhang L, Li L
Discover oncology 2024 Jun 10;15(1):217
Discover oncology 2024 Jun 10;15(1):217
3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.
Zhang R, Guan S, Meng Z, Deng X, Lu J
Journal of agricultural and food chemistry 2024 Jun 10;
Journal of agricultural and food chemistry 2024 Jun 10;
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Zhou GQ, Wang X, Gao P, Qin TZ, Guo L, Zhang ZW, Huang ZF, Lin JJ, Jing YT, Wang HN, Wang CP, Ding GR
The Science of the total environment 2024 Jun 1;927:172391
The Science of the total environment 2024 Jun 1;927:172391
Hsa_circ_0096157 silencing suppresses autophagy and reduces cisplatin resistance in non-small cell lung cancer by weakening the Nrf2/ARE signaling pathway.
Lu H, Kong J, Cai S, Huang H, Luo J, Liu L
Molecular biology reports 2024 Jun 1;51(1):703
Molecular biology reports 2024 Jun 1;51(1):703
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Xing H, Xu P, Ma Y, Li T, Zhang Y, Ding X, Liu L, Keerman M, Niu Q
Environmental toxicology 2024 Jul;39(7):3779-3789
Environmental toxicology 2024 Jul;39(7):3779-3789
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Qi J, Wu Y, Guo Z, Zhu S, Xiong J, Hu F, Liang X, Ye X
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Zhang GD, Wang MM, Su Y, Fang H, Xue XL, Liu HK, Su Z
Journal of inorganic biochemistry 2024 Jul;256:112574
Journal of inorganic biochemistry 2024 Jul;256:112574
FUDNC1-dependent mitophagy ameliorate motor neuron death in an amyotrophic lateral sclerosis mouse model.
Guo X, Zhang Z, Gu J, Ke P, Liu J, Meng Y, Zheng W, Que W, Fan R, Luo J, Xiao F
Neurobiology of disease 2024 Jul;197:106534
Neurobiology of disease 2024 Jul;197:106534
Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro.
Ping Z, Shuxia Z, Xinyu D, Kehe H, Xingxiang C, Chunfeng W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jul;189:114714
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jul;189:114714
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice.
Wu Y, Zhang H, Wang Y, Zhang Y, Hong Z, Wang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116869
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116869
THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B-CaMKII-ERK1/2 pathway.
Liu T, Shi J, Wu D, Li D, Wang Y, Liu J, Meng P, Hu L, Fu C, Mei Z, Ge J, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155595
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155595
The HSP90AA1 gene is involved in heat stress responses and its functional genetic polymorphisms are associated with heat tolerance in Holstein cows.
Hu L, Fang H, Abbas Z, Luo H, Brito LF, Wang Y, Xu Q
Journal of dairy science 2024 Jul;107(7):5132-5149
Journal of dairy science 2024 Jul;107(7):5132-5149
Neonatal Exposure to Polystyrene Nanoplastics Impairs Microglia-Mediated Synaptic Pruning and Causes Social Behavioral Defects in Adulthood.
Zou L, Xu X, Wang Y, Lin F, Zhang C, Liu R, Hou X, Wang J, Jiang X, Zhang Q, Li L
Environmental science & technology 2024 Jul 9;58(27):11945-11957
Environmental science & technology 2024 Jul 9;58(27):11945-11957
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Su S, Liu L, Fu Q, Ma M, Yang N, Pan T, Geng S, Yu XF, Zhu J
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Paeoniflorin Promotes Ovarian Development in Mice by Activating Mitophagy and Preventing Oxidative Stress.
Xi H, Wang Z, Li M, Duan X, Li Y
International journal of molecular sciences 2024 Jul 30;25(15)
International journal of molecular sciences 2024 Jul 30;25(15)
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617
Journal of translational medicine 2024 Jul 3;22(1):617
Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor.
Zhou Z, Huang S, Fan S, Li X, Wang C, Yu W, Du D, Zhang Y, Chen K, Fu W, Luo C
Journal of medicinal chemistry 2024 Jul 25;67(14):12184-12204
Journal of medicinal chemistry 2024 Jul 25;67(14):12184-12204
Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response.
Liu Y, Gu Y, Chen Y, Wang X, Zhou G, Li J, Wang M, Fang S, Yang Y
Cell reports 2024 Jul 23;43(7):114402
Cell reports 2024 Jul 23;43(7):114402
Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering.
Zhang WY, Wei QQ, Zhang T, Wang CS, Chen J, Wang JH, Xie X, Jiang P
Journal of neuroinflammation 2024 Jul 20;21(1):177
Journal of neuroinflammation 2024 Jul 20;21(1):177
Defective ferritinophagy and imbalanced iron metabolism in PBDE-47-triggered neuronal ferroptosis and salvage by Canolol.
Wang Y, Li X, Qu T, Huang F, Xu J, Gao H, Zhang S
The Science of the total environment 2024 Jul 15;934:173118
The Science of the total environment 2024 Jul 15;934:173118
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
Han L, Chen W, Li J, Zhao Y, Zong Y, He Z, Du R
Brain research 2024 Jul 15;1835:148932
Brain research 2024 Jul 15;1835:148932
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia‒reperfusion injury.
Ding X, Gao X, Ren A, Xu J, Jiang X, Liang X, Xie K, Zhou Y, Hu C, Huang D
Chemico-biological interactions 2024 Jul 1;397:111078
Chemico-biological interactions 2024 Jul 1;397:111078
CDK5-USP30 signaling pathway regulates MAVS-mediated inflammation via suppressing mitophagy in MPTP/MPP(+) PD model.
Ren Y, Wu X, Bai T, Yang N, Yuan Y, Xu L, Wen Y, Wen Y, Wang Z, Zhou L, Zou F, Li W
Ecotoxicology and environmental safety 2024 Jul 1;279:116446
Ecotoxicology and environmental safety 2024 Jul 1;279:116446
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
Luo QQ, Tian Y, Qu GJ, Huang K, Hu PP, Xue Y, Hu BF, Luo SS
Molecular reproduction and development 2024 Jan;91(1):e23724
Molecular reproduction and development 2024 Jan;91(1):e23724
GPSM1 in POMC neurons impairs brown adipose tissue thermogenesis and provokes diet-induced obesity.
Tang M, Zhang Y, Zhang R, Zhang Y, Zheng J, Wang D, Wang X, Yan J, Hu C
Molecular metabolism 2024 Jan;79:101839
Molecular metabolism 2024 Jan;79:101839
Overexpression of SESN1 improves mitochondrial damage and mitophagy, a potential therapeutic strategy for cognitive dysfunction after anaesthesia.
Sun L, Hong X, Wang D, Li Y
The European journal of neuroscience 2024 Jan;59(2):208-219
The European journal of neuroscience 2024 Jan;59(2):208-219
Human filaggrin monomer does not seem to be a proteasome target.
Briot J, Arbey E, Goudounèche D, Bernard D, Simon M, Méchin MC
Experimental dermatology 2024 Jan;33(1):e14772
Experimental dermatology 2024 Jan;33(1):e14772
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy.
Toriyama K, Okuma T, Abe S, Nakamura H, Aoshiba K
Oncology letters 2024 Jan;27(1):12
Oncology letters 2024 Jan;27(1):12
CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in LPS-induced mouse model of depression.
Zhou Z, Ye Q, Ren H, Zhang Y, Han B, Yao H, Bai Y
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.
Deng Z, He M, Hu H, Zhang W, Zhang Y, Ge Y, Ma T, Wu J, Li L, Sun M, An S, Li J, Huang Q, Gong S, Zhang J, Chen Z, Zeng Z
Autophagy 2024 Jan;20(1):151-165
Autophagy 2024 Jan;20(1):151-165
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
Lu J, Zhang L, Zhu N, Wang D, Xie F, Qin M, Wang Y
Archives of oral biology 2024 Jan;157:105851
Archives of oral biology 2024 Jan;157:105851
Exosomal microRNA profiling revealed enhanced autophagy suppression and anti-tumor effects of a combination of compound Phyllanthus urinaria and lenvatinib in hepatocellular carcinoma.
Liao M, Qin M, Liu L, Huang H, Chen N, Du H, Huang D, Wang P, Zhou H, Tong G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155091
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Li X, Gu Y, Ren L, Cai Q, Qiu Y, He J, Qu W, Ji W
Chemical biology & drug design 2024 Jan;103(1):e14367
Chemical biology & drug design 2024 Jan;103(1):e14367
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells.
Xia Q, Xie J, Zhang J, Zhang L, Zhou Y, Zhu B, Wu Y, Yang Z, Li J
Chemico-biological interactions 2024 Jan 5;387:110819
Chemico-biological interactions 2024 Jan 5;387:110819
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
Sun P, Wang Z, Li S, Yin J, Gan Y, Liu S, Lin Z, Wang H, Fan Z, Qu Q, Hu Z, Li K, Miao Y
Cell & bioscience 2024 Jan 5;14(1):6
Cell & bioscience 2024 Jan 5;14(1):6
Targeting ENPP1 depletion may be a promising therapeutic strategy for treating oral squamous cell carcinoma via cytotoxic autophagy-related apoptosis.
Ma C, Zhao J, Zhou L, Jia C, Shi Y, Li X, Jihu K, Zhang T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23420
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23420
Evidence for Involvement of ADP-Ribosylation Factor 6 in Intracellular Trafficking and Release of Murine Leukemia Virus Gag.
Kang H, Kang T, Jackson L, Murphy A, Nitta T
Cells 2024 Jan 31;13(3)
Cells 2024 Jan 31;13(3)
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Wang R, Zeng J, Chen L, Sun L, Wang Y, Xu J, He X
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region.
Zhao Z, Xie L, Shi J, Liu T, Wang S, Huang J, Wu D, Zhang X
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117172
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117172
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Wang J, Zheng F, Wang D, Yang Q
Cell death & disease 2024 Jan 29;15(1):97
Cell death & disease 2024 Jan 29;15(1):97
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
Zhang B, He Z, Guo J, Li F, Huang Z, Zheng W, Xing W, Li M, Zhu Y, Yang X
Aging 2024 Jan 26;16(2):1145-1160
Aging 2024 Jan 26;16(2):1145-1160
SNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway.
Yang W, Li L, Zhang J, Wu J, Kang W, Wang Y, Ding H, Li D, Zheng H
Journal of virology 2024 Jan 23;98(1):e0159923
Journal of virology 2024 Jan 23;98(1):e0159923
Quercetin stimulates trophoblast fusion via the mitochondrial function.
Yoshida K, Kusama K, Shinohara G, Sato S, Yoshie M, Tamura K
Scientific reports 2024 Jan 2;14(1):287
Scientific reports 2024 Jan 2;14(1):287
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200
Theriogenology 2024 Jan 15;214:192-200
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Chen H, Yang X, Gao Y, Jiang H, Guo M, Zhou Y, Li C, Tan Y, Zhang Y, Xue W
Brain research 2024 Jan 15;1823:148683
Brain research 2024 Jan 15;1823:148683
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Li P, Dou Q, Zhang D, Xiang Y, Tan L
Aging 2024 Jan 10;16(1):844-856
Aging 2024 Jan 10;16(1):844-856
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Hu J, Hou W, Ma N, Zhang Y, Liu X, Wang Y, Ci X
Life sciences 2024 Jan 1;336:122352
Life sciences 2024 Jan 1;336:122352
Interleukin-37 relieves PM2.5-triggered lung injury by inhibiting autophagy through the AKT/mTOR signaling pathway in vivo and in vitro.
Cao J, Hou S, Chen Z, Yan J, Chao L, Qian Y, Li J, Yan X
Ecotoxicology and environmental safety 2024 Jan 1;269:115816
Ecotoxicology and environmental safety 2024 Jan 1;269:115816
Autophagy activation alleviates the LPS-induced inflammatory response in endometrial epithelial cells in dairy cows.
Dong J, Ji B, Jiang Y, Liu K, Guo L, Cui L, Wang H, Li B, Li J
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Feb;91(2):e13820
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Feb;91(2):e13820
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Huang H, Yan J, Xu X, Feng Y, Liu H, Liu J, Xie M, Chen L, Xiang D, Peng W, Zeng L, Zeng Y, Chen F, Zhang S, Liu Q
Drug development research 2024 Feb;85(1):e22140
Drug development research 2024 Feb;85(1):e22140
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Xu H, Fu J, Tu Q, Shuai Q, Chen Y, Wu F, Cao Z
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Reticulon 3 regulates sphingosine-1-phosphate synthesis in endothelial cells to control blood pressure.
Jin JY, Chang SH, Chen YQ, Liu MW, Dong Y, Liu JS, Wang Q, Huang H, Fan LL, Xiang R
MedComm 2024 Feb;5(2):e480
MedComm 2024 Feb;5(2):e480
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells.
Zhao YY, Li J, Wang HQ, Zheng HB, Ma SW, Zhou GZ
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23642
Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway.
Li S, Chen T, Zhou Y, Li X
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166972
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166972
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents.
Lin G, Zhong Y, Hu S, He F, Zhang Z, Li W, Hu H, Zeng JZ
Bioorganic chemistry 2024 Feb;143:107022
Bioorganic chemistry 2024 Feb;143:107022
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC Jr, Kirwan JP, Axelrod CL, Singh P
Physiological reports 2024 Feb;12(3):e15948
Physiological reports 2024 Feb;12(3):e15948
Inhibition of SIRT7 promotes STAT1 activation and STAT1-dependent signaling in hepatocellular carcinoma.
Dong L, Wei X, Yu L, Li Y, Chen L
Cellular signalling 2024 Feb;114:111005
Cellular signalling 2024 Feb;114:111005
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Dan Z, Shi X, Shu C, Zhu R, Wang Y, Zhu H
Cellular signalling 2024 Feb;114:111001
Cellular signalling 2024 Feb;114:111001
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chen B, Zhao Y, Xu S, Jiang F, Nie Y, Tang A, Zhou Q
Annals of hematology 2024 Feb;103(2):533-544
Annals of hematology 2024 Feb;103(2):533-544
Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte.
Tu WJ, Zhang YH, Wang XT, Zhang M, Jiang KY, Jiang S
Poultry science 2024 Feb;103(2):103293
Poultry science 2024 Feb;103(2):103293
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
Cheng S, Liu Y, He B, Zhang J, Yang Y, Wang X, Li Z
Pathogens and disease 2024 Feb 7;82
Pathogens and disease 2024 Feb 7;82
BOP1 contributes to the activation of autophagy in polycystic ovary syndrome via nucleolar stress response.
Ji R, Zhang Z, Yang Z, Chen X, Yin T, Yang J
Cellular and molecular life sciences : CMLS 2024 Feb 27;81(1):101
Cellular and molecular life sciences : CMLS 2024 Feb 27;81(1):101
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility.
Wang X, Fan X, Zhang J, Wang F, Chen J, Wen Y, Wang L, Li T, Li H, Gu H, Zhang Y, Yuan S
Cell reports 2024 Feb 27;43(2):113769
Cell reports 2024 Feb 27;43(2):113769
PPAR γ activation in chondrocytes alleviates glucocorticoid-induced oxidative stress, mitochondrial impairment, and pyroptosis via autophagic flow enhancement.
Wu D, Shen Z, Gou Y, Yu T, Hong J, Wang Y, Ni F, Qiqige N, Lu H, Xue E
Chemico-biological interactions 2024 Feb 25;390:110877
Chemico-biological interactions 2024 Feb 25;390:110877
Synergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence.
Li N, Jiang X, Zhang Q, Huang Y, Wei J, Zhang H, Luo H
Journal of ovarian research 2024 Feb 23;17(1):49
Journal of ovarian research 2024 Feb 23;17(1):49
Gonococcal OMV-delivered PorB induces epithelial cell mitophagy.
Gao S, Gao L, Yuan D, Lin X, van der Veen S
Nature communications 2024 Feb 23;15(1):1669
Nature communications 2024 Feb 23;15(1):1669
M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.
Wu S, Qiu C, Ni J, Guo W, Song J, Yang X, Sun Y, Chen Y, Zhu Y, Chang X, Sun P, Wang C, Li K, Han X
Nature communications 2024 Feb 22;15(1):1646
Nature communications 2024 Feb 22;15(1):1646
Mitochondria-mediated ferroptosis contributes to the inflammatory responses of bovine viral diarrhea virus (BVDV) in vitro.
Li Z, Zhao B, Zhang Y, Fan W, Xue Q, Chen X, Wang J, Qi X
Journal of virology 2024 Feb 20;98(2):e0188023
Journal of virology 2024 Feb 20;98(2):e0188023
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Feng J, Li Y, Zhang Y, Sun S, Sun J, Xu Q, Ji X, Liu Y, Wan Q
Journal of translational medicine 2024 Feb 16;22(1):161
Journal of translational medicine 2024 Feb 16;22(1):161
Activation of the p62-Keap1-Nrf2 pathway improves pulmonary arterial hypertension in MCT-induced rats by inhibiting autophagy.
Jiang G, Shi LF, Li LJ, Duan XJ, Zheng ZF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 15;38(3):e23452
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 15;38(3):e23452
2'-Hydroxychalcone Induces Autophagy and Apoptosis in Breast Cancer Cells via the Inhibition of the NF-κB Signaling Pathway: In Vitro and In Vivo Studies.
Wang X, Liang Y, Zhang B, He L, Li W, Zhang W, Li C, Luo L, Umar T, Feng H, Qiu C
Nutrients 2024 Feb 13;16(4)
Nutrients 2024 Feb 13;16(4)
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy.
Wu J, Xu W, Li J, Luo C, Chen B, Lin L, Huang T, Luo T, Yang L, Yang J
Molecular and cellular probes 2024 Dec;78:101988
Molecular and cellular probes 2024 Dec;78:101988
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1.
Yuan Y, Huang H, Hu T, Zou C, Qiao Y, Fang M, Liu J, Lai S
International journal of molecular medicine 2024 Dec;54(6)
International journal of molecular medicine 2024 Dec;54(6)
ATF4/PHGDH mediates the effects of ER stress on cadmium-induced autophagy and glycolysis.
Yang Y, Li S, Yang Y, Li Q, Liu Y, Cao J
Toxicology 2024 Dec;509:153976
Toxicology 2024 Dec;509:153976
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Kong J, Dong Y, Li M, Fan J, Wang T
Toxicology and applied pharmacology 2024 Dec;493:117145
Toxicology and applied pharmacology 2024 Dec;493:117145
Association between mitophagy and NLRP3 inflammasome in uric acid nephropathy.
Li XQ, Gu YQ, Ling YY, Wang M, Miao J, Xue L, Ji W, Liu J
Renal failure 2024 Dec;46(2):2438847
Renal failure 2024 Dec;46(2):2438847
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y
Renal failure 2024 Dec;46(1):2338933
Renal failure 2024 Dec;46(1):2338933
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.
Xi ZC, Ren HG, Ai L, Wang Y, Liu MF, Qiu YF, Feng JL, Fu W, Bi QQ, Wang F, Xu HX
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
Acta pharmacologica Sinica 2024 Dec;45(12):2474-2486
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Wang S, Li C, Kang X, Su X, Liu Y, Wang Y, Liu S, Deng X, Huang H, Li T, Lu D, Cai W, Lu Z, Wei L, Lu T
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Cai S, Ding R, Zhang H, Chen Q, Yu F, Xia Y, Chen Q, Miao X, Zhou B, Chen J, Liao L, Cheng X, Fu X
Materials today. Bio 2024 Dec;29:101323
Materials today. Bio 2024 Dec;29:101323
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
Chen KY, Cheng CJ, Chang YT, Lin YH, Huang YH, Lin SY, Wang LC, Jhan KY, Chiu CH
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins.
Zhou P, Zhang Q, Yang Y, Wu W, Chen D, Zheng Z, Jongkaewwattana A, Jin H, Zhou H, Luo R
Autophagy 2024 Dec;20(12):2769-2784
Autophagy 2024 Dec;20(12):2769-2784
Degarelix limits the survival of mycobacteria and granuloma formation.
Li J, Gao J, Gao Y, Shi C, Guo X, Huang H, Wang J, Huang X, Chen H, Huang J, Wang W, Yang H
Microbial pathogenesis 2024 Dec;197:107046
Microbial pathogenesis 2024 Dec;197:107046
The RIP3 activator C8 regulates the autophagy flux mediated by p62 and promotes the immunogenic form of cell death in human gastric cancer cells.
Liu X, Jin Y, Zhang M, Jin Y, Cao J, Dong H, Fu X, Jin CY
Bioorganic chemistry 2024 Dec;153:107937
Bioorganic chemistry 2024 Dec;153:107937
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Chen Z, Zhang M, Xu Q, Lu P, Liu M, Yin R, Liu X, Dai Y, Gao X, Gong J, Zhang S, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.
Zhang M, Cui Y, Jia R, Cai Z, Shen Y, Yu W, Pang Z, Ding S, Gao X, Huang Y, Song M, Lou Y, Ye F, Ao H, Zhu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156132
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156132
Lipopolysaccharide-regulated RNF31/NRF2 axis in colonic epithelial cells mediates homeostasis of the intestinal barrier in ulcerative colitis.
Tang CT, Liu ZD, Wang P, Zeng CY, Chen YX
Cellular signalling 2024 Dec;124:111480
Cellular signalling 2024 Dec;124:111480
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
Hu HF, Fu JY, Han L, Gao GB, Zhang WX, Yu SM, Li N, Li YJ, Lu YF, Ding XF, Pan YL, Wang Y, He QY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions.
Oh SJ, Shin YY, Ahn JS, Park HJ, Kang MJ, Shin TH, Lee BC, Kim WK, Oh JM, Lee D, Kim YH, Kim JM, Sung ES, Lee EW, Jeong JH, Lee BJ, Seo Y, Kim HS
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2400660
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2400660
Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity.
Ritika, Liao ZY, Chen PY, Rao NV, Mathew J, Sharma R, Grewal AS, Singh G, Mehan S, Liou JP, Pan CH, Nepali K
European journal of medicinal chemistry 2024 Dec 5;279:116866
European journal of medicinal chemistry 2024 Dec 5;279:116866
Fisetin Ameliorates Hepatocyte Lipid Droplet Accumulation via Targeting the Rhythmic Protein BMAL1 to Regulate Cell Death-Inducing DNA Fragmentation Factor-α-like Effector C-Mediated Lipid Droplet Fusion.
Zhang R, Liu M, Lu J, Lu S, Wang Y, Guan S
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26884-26897
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26884-26897
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Wang Y, Guo J, Zhang D, Shi C, Zhang X, Gong Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
Stilbene glycosides alleviate atherosclerosis partly by promoting lipophagy of dendritic cells.
Yang Y, Bai D, Jiang L, Chen Y, Wang M, Wang W, Wang H, He Q, Bu G, Long J, Yuan D
International immunopharmacology 2024 Dec 25;143(Pt 1):113223
International immunopharmacology 2024 Dec 25;143(Pt 1):113223
mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin.
Zheng K, Gao Y, Xu J, Kang M, Chai R, Jin G, Kang Y
Biomedicines 2024 Dec 24;13(1)
Biomedicines 2024 Dec 24;13(1)
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Redox homeostasis of one-carbon metabolism-dependent reprogramming is critical for RCC progression under exogenous serine/glycine-deprived conditions.
Wang H, Fan M, Liu S, Qu M, Hou X, Hou J, Xu Y, Shang X, Liu C, He M, Gao J, Chen J, Li X
BMC cancer 2024 Dec 18;24(1):1515
BMC cancer 2024 Dec 18;24(1):1515
LOC730101 improves ovarian cancer drug sensitivity by inhibiting autophagy-mediated DNA damage repair via BECN1.
Zhong Y, Shuai Y, Yang J, Zhang M, He T, Zheng L, Yang S, Peng S
Cell death & disease 2024 Dec 18;15(12):893
Cell death & disease 2024 Dec 18;15(12):893
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Qiu H, Gao L, Shi W, Wang J, Li B, Ke S, Chen J, Gong Y, Wu Y, Zhao W, Chen Y
Cancer letters 2024 Dec 16;611:217401
Cancer letters 2024 Dec 16;611:217401
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Pan C, Wang K, Hong R, Wang X, Zhang Y, Fan Z, Shi Y, Liu T, Chen H
Environmental research 2024 Dec 15;263(Pt 2):120098
Environmental research 2024 Dec 15;263(Pt 2):120098
DEHP regulates ferritinophagy to promote testicular ferroptosis via suppressing SIRT1/PGC-1α pathway.
Zhu Q, Zhai J, Chen Z, Guo Z, Sun X, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
The Science of the total environment 2024 Dec 1;954:176497
The Science of the total environment 2024 Dec 1;954:176497
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
Lin Y, Cheng L, Chen Y, Li W, Guo Q, Miao Y
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes.
Zheng Y, Chen J, Macwan V, Dixon CL, Li X, Liu S, Yu Y, Xu P, Sun Q, Hu Q, Liu W, Raught B, Fairn GD, Neculai D
Nature metabolism 2024 Aug;6(8):1549-1565
Nature metabolism 2024 Aug;6(8):1549-1565
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Lv S, Jiang H, Yu L, Zhang Y, Sun L, Xu J
Journal of molecular histology 2024 Aug;55(4):391-401
Journal of molecular histology 2024 Aug;55(4):391-401
Curcumin inhibits PAT-induced renal ferroptosis via the p62/Keap1/Nrf2 signalling pathway.
Zhai J, Chen Z, Zhu Q, Guo Z, Sun X, Jiang L, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Toxicology 2024 Aug;506:153863
Toxicology 2024 Aug;506:153863
EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis.
Liu X, Gao X, Yang Y, Yang D, Guo Q, Li L, Liu S, Cong W, Lu S, Hou L, Wang B, Li N
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1161-1184
Apoptosis : an international journal on programmed cell death 2024 Aug;29(7-8):1161-1184
Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway.
Xia Y, Zhang H, Wu X, Xu Y, Tan Q
Biogerontology 2024 Aug;25(4):649-664
Biogerontology 2024 Aug;25(4):649-664
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Yue C, Lu W, Fan S, Huang Z, Yang J, Dong H, Zhang X, Shang Y, Lai W, Li D, Dong T, Yuan A, Wu J, Kang L, Hu Y
Nature nanotechnology 2024 Aug;19(8):1203-1215
Nature nanotechnology 2024 Aug;19(8):1203-1215
Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway.
Tang X, Gong J, Ren L, Wang Z, Yang B, Wang W, Wang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117037
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117037
Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats.
Liang JH, Yu H, Xia CP, Zheng YH, Zhang Z, Chen Y, Raza MA, Wu L, Yan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117006
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117006
Novel meroterpene-like compounds inhibit ferroptosis through Fe(2+) chelation.
Lou S, Liu YX, Xia C, Zhang Q, Deng L, Tang JJ
The international journal of biochemistry & cell biology 2024 Aug;173:106610
The international journal of biochemistry & cell biology 2024 Aug;173:106610
L-Alanine promotes anti-infectious properties of Bacillus subtilis S-2 spores via the germination receptor gerAA.
Lu S, Liao X, Lu W, Zhang L, Na K, Li X, Guo X
Probiotics and antimicrobial proteins 2024 Aug;16(4):1399-1410
Probiotics and antimicrobial proteins 2024 Aug;16(4):1399-1410
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
Liu N, Cui X, Yan W, Guo T, Wang Z, Wei X, Sun Y, Liu J, Xian C, Ma W, Chen L
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
Melatonin alleviates palmitic acid-induced mitochondrial dysfunction by reducing oxidative stress and enhancing autophagy in bovine endometrial epithelial cells.
Wang Y, Gong J, Heng N, Hu Y, Wang R, Wang H, He W, Zhu N, Hu Z, Hao H, Zhu H, Zhao S
Journal of animal science and biotechnology 2024 Aug 8;15(1):108
Journal of animal science and biotechnology 2024 Aug 8;15(1):108
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
He L, Tian Y, Liu Q, Bao J, Ding RB
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
Identification and Validation of the miR/RAS/RUNX2 Autophagy Regulatory Network in AngII-Induced Hypertensive Nephropathy in MPC5 Cells Treated with Hydrogen Sulfide Donors.
Ye Q, Ren M, Fan D, Mao Y, Zhu YZ
Antioxidants (Basel, Switzerland) 2024 Aug 7;13(8)
Antioxidants (Basel, Switzerland) 2024 Aug 7;13(8)
NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling.
Wang S, Qiao X, Cui Y, Liu L, Cooper T, Hu Y, Lin J, Liu H, Wang M, Hayball J, Wang X
Cell death & disease 2024 Aug 6;15(8):565
Cell death & disease 2024 Aug 6;15(8):565
RILP Induces Cholesterol Accumulation in Lysosomes by Inhibiting Endoplasmic Reticulum-Endolysosome Interactions.
Han Y, Liu X, Xu L, Wei Z, Gu Y, Ren Y, Hua W, Zhang Y, Liu X, Jiang C, Zhuang R, Hong W, Wang T
Cells 2024 Aug 6;13(16)
Cells 2024 Aug 6;13(16)
Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Segura-Roman A, Citron YR, Shin M, Sindoni N, Maya-Romero A, Rapp S, Goul C, Mancias JD, Zoncu R
bioRxiv : the preprint server for biology 2024 Aug 6;
bioRxiv : the preprint server for biology 2024 Aug 6;
Cajaninstilbene acid ameliorates depression-like behaviors in mice by suppressing TLR4/NF-κB mediated neuroinflammation and promoting autophagy.
Tao X, Zhou Y, Wang Z, Wang L, Xia T, Yan M, Chang Q
Behavioural brain research 2024 Aug 5;471:115142
Behavioural brain research 2024 Aug 5;471:115142
Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis.
Liu J, Zhou H, Chen J, Zuo Q, Liu F
Physiological research 2024 Aug 31;73(4):633-642
Physiological research 2024 Aug 31;73(4):633-642
Regulatory role of the mTOR signaling pathway in autophagy and mesangial proliferation in IgA nephropathy.
Liu Y, Leng B, Xia M, Liu D, Tan X, Chen G, He L, Wang C, Zhu X, Liu H
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2024 Aug 28;49(8):1220-1231
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2024 Aug 28;49(8):1220-1231
Mitochondria-Targeted Multifunctional Nanoprodrugs by Inhibiting Metabolic Reprogramming for Combating Cisplatin-Resistant Lung Cancer.
Lu H, Tong W, Jiang M, Liu H, Meng C, Wang K, Mu X
ACS nano 2024 Aug 13;18(32):21156-21170
ACS nano 2024 Aug 13;18(32):21156-21170
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Luo YW, Zhou JP, Ji H, Xu D, Zheng A, Wang X, Dai Z, Luo Z, Cao F, Wang XY, Bai Y, Chen D, Chen Y, Wang Q, Yang Y, Zhang X, Chiu S, Peng X, Huang AL, Tang KF
Nature communications 2024 Aug 13;15(1):6964
Nature communications 2024 Aug 13;15(1):6964
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Zhang W, Peng H, Yang D, Song G, He J, Zhou Y, Huang C, Huang B
Neuroscience letters 2024 Aug 10;837:137921
Neuroscience letters 2024 Aug 10;837:137921
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
Luo L, Lin J, Chen S, Ni J, Peng H, Shen F, Huang Z
Journal of ethnopharmacology 2024 Aug 10;330:118196
Journal of ethnopharmacology 2024 Aug 10;330:118196
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Li H, Wu D, Zhang H, Liu S, Zhen J, Yan Y, Li P
BMC gastroenterology 2024 Aug 1;24(1):245
BMC gastroenterology 2024 Aug 1;24(1):245
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Li Y, Liu W, Zhao R, An Y, Zhang M, Ren X, He H
International dental journal 2024 Apr;74(2):284-293
International dental journal 2024 Apr;74(2):284-293
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Zhang S, Zhao N, Song S, Wang Y, Wang Y, Sun C, Dong M, Huo M, Xu N, Liu W, Li G
Toxicology and applied pharmacology 2024 Apr;485:116890
Toxicology and applied pharmacology 2024 Apr;485:116890
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G
Inflammation 2024 Apr;47(2):718-732
Inflammation 2024 Apr;47(2):718-732
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
Luo L, Ni J, Zhang J, Lin J, Chen S, Shen F, Huang Z
Toxicology letters 2024 Apr;394:102-113
Toxicology letters 2024 Apr;394:102-113
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
Zuo Z, Li Q, Zhou S, Yu R, Wu C, Chen J, Xiao Y, Chen H, Song J, Pan Y, Wang W
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress.
Luo J, Li P, Dong M, Zhang Y, Lu S, Chen M, Zhou H, Lin N, Jiang H, Wang Y
Cell death and differentiation 2024 Apr;31(4):417-430
Cell death and differentiation 2024 Apr;31(4):417-430
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Cao G, Kang T, Li N, Li P
Experimental and therapeutic medicine 2024 Apr;27(4):135
Experimental and therapeutic medicine 2024 Apr;27(4):135
Characterization and function of PTEN-induced putative kinase 1 (PINK1) in process of Zinc alleviates hepatic lipid deposition of yellow catfish (Pelteobagrus fulvidraco).
Xiao L, Chen B, Chen C, Xiao F, Li M, Zhuang M, Dai Y, Wu K
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
International journal of biological macromolecules 2024 Apr;265(Pt 2):131156
MiR-181a-5p may regulate cell proliferation and autophagy in myopia and the associated retinopathy.
Jiang B, Hong N, Zhang L, Xu B, He Q, Qian X, Li F, Dong F
Experimental eye research 2024 Apr;241:109829
Experimental eye research 2024 Apr;241:109829
CIRBP Increases the synthesis and secretion of steroid hormones by in yak granulaso cells.
Zhang R, Pan Y, Wang M, Wang J, Zhang T, Zhao L, Xu R, Wang Y, Han X, Ye X, Cui Y, Yu S
The Journal of steroid biochemistry and molecular biology 2024 Apr;238:106449
The Journal of steroid biochemistry and molecular biology 2024 Apr;238:106449
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Liu H, Zhou L, Wang X, Zheng Q, Zhan F, Zhou L, Dong Y, Xiong Y, Yi P, Xu G, Hua F
Biochemical pharmacology 2024 Apr;222:116050
Biochemical pharmacology 2024 Apr;222:116050
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Chen L, Zhao Z, Diarimalala RO, Chen Z, Wang Y, Zhan T, Zhao Y, Ma C, Wang X, Zhao C, Xiao Z, Hu K, Wu P
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Selenomethionine Inhibits NF-κB-mediated Inflammatory Responses of Bovine Mammary Epithelial Cells Caused by Klebsiella pneumoniae by Increasing Autophagic Flux.
Xu S, Miao Y, Dong J, Cui L, Liu K, Li J, Meng X, Zhu G, Wang H
Biological trace element research 2024 Apr;202(4):1568-1581
Biological trace element research 2024 Apr;202(4):1568-1581
DDIT3/CHOP promotes LPS/ATP-induced pyroptosis in osteoblasts via mitophagy inhibition.
Dong Z, Yang B, Jia M, Yang C, Wang S, Mu H, Wang J
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119712
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119712
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
Duan H, Pan C, Wu T, Peng J, Yang L
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Wu H, Qu L, Bai X, Zhu C, Liu Y, Duan Z, Liu H, Fu R, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Zhang R, Guan S, Meng Z, Zhang D, Lu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Nie J, Mao Z, Zeng X, Zhao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
TFEB regulates the odontoblastic differentiation of dental pulp stem cells by promoting a positive feedback loop between mitophagy and glycolysis.
Li Y, Yang E, Geng Y, Li M, Wang X, Zhang D
Archives of oral biology 2024 Apr;160:105909
Archives of oral biology 2024 Apr;160:105909
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
Ding X, Cao S, Wang Q, Du B, Lu K, Qi S, Cheng Y, Tuo QZ, Liang W, Lei P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
Effect of beta-cypermethrin on the reproductive capacity of female mice in advanced age.
Qiao QF, Wang LQ, Yu DE, Li N, Xu QJ, Zhou YJ
Environmental toxicology and pharmacology 2024 Apr;107:104410
Environmental toxicology and pharmacology 2024 Apr;107:104410
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Qi C, Lv C, Jiang M, Zhao X, Gao Y, Wang Y, Zhang P, Liu J, Zhao X
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Chen Y, Yuan C, Qin W, Yu B, Wei D, Wu P
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Biochemical and biophysical research communications 2024 Apr 9;703:149667
HACD3 Prevents PB1 from Autophagic Degradation to Facilitate the Replication of Influenza A Virus.
Li Q, Jiang L, Wang Y, Liu X, Wang B, Shan Z, Wang YH, Wang Y, Chen H, Li C
Viruses 2024 Apr 29;16(5)
Viruses 2024 Apr 29;16(5)
RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation.
Ying R, Li C, Li H, Zou J, Hu M, Hong Q, Shen Y, Hou L, Cheng H, Zhou R
Cell reports 2024 Apr 23;43(4):114010
Cell reports 2024 Apr 23;43(4):114010
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Wu Y, Li L, Wang L, Zhang S, Zeng Z, Lu J, Wang Z, Zhang Y, Zhang S, Li H, Chen T
BMC cancer 2024 Apr 22;24(1):506
BMC cancer 2024 Apr 22;24(1):506
Protective effects of pulsed electromagnetic field therapy attenuates autophagy and apoptosis in osteoporotic osteoarthritis model rats by activating PPARγ.
Liu J, Zhou J, Huang X, Yin L, Zhou L, Liao Y, Sun G, Zhong P, Peng X, Sun Z
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):61-70
Electromagnetic biology and medicine 2024 Apr 2;43(1-2):61-70
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Ma X, Yin J, Qiao L, Wan H, Liu X, Zhou Y, Wu J, Niu L, Wu M, Wang X, Ye H
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Tang X, Luo X, Wang X, Zhang Y, Xie J, Niu X, Lu X, Deng X, Xu Z, Wu F
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Wang Y, Gu L, Li J, Wang R, Zhuang Y, Li X, Wang X, Zhang J, Liu Q, Wang J, Song SJ
European journal of medicinal chemistry 2024 Apr 15;270:116312
European journal of medicinal chemistry 2024 Apr 15;270:116312
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
Triamcinolone acetonide induces the autophagy of Ag85B-treated WI-38 cells via SIRT1/FOXO3 pathway.
Luo L, Zhou L, Luo L, Feng D, Ding Y, Lu Z, Nie G, Bai L, Xiao Y
Allergologia et immunopathologia 2023;51(2):27-35
Allergologia et immunopathologia 2023;51(2):27-35
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Zhang F, Wang M, Li Z, Deng J, Fan Y, Gou Z, Zhou Y, Huang L, Lu L
Experimental lung research 2023;49(1):178-192
Experimental lung research 2023;49(1):178-192
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Mao X, Xie X, Ma J, Wei Y, Huang Z, Wang T, Zhu J, Wang Y, Zhao H, Hua J
Biological & pharmaceutical bulletin 2023;46(7):929-938
Biological & pharmaceutical bulletin 2023;46(7):929-938
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Liang HY, Peng F, Pan MJ, Liao SL, Wei C, Wei GY, Xie X, Xue KY, Chen MK, Yang JK, Guo WB, Liu CD, Zhou QZ
Asian journal of andrology 2023;25(4):474-483
Asian journal of andrology 2023;25(4):474-483
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.
Su R, Yin J, Ruan X, Chen Y, Wan P, Luo Z
Computational and structural biotechnology journal 2023;21:4478-4487
Computational and structural biotechnology journal 2023;21:4478-4487
Deciphering the Molecular Mechanism of Yifei-Sanjie Pill in Cancer-Related Fatigue.
Wu Y, Zhou S, Pi D, Dong Y, Wang W, Ye H, Yi Z, Chen Y, Lin L, Ouyang M
Journal of oncology 2023;2023:5486017
Journal of oncology 2023;2023:5486017
Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.
Yu Y, Ren Y, Li Z, Li Y, Li Y, Zhang Y, Gui R, Cui Y, Qian L, Xiong Y
Oxidative medicine and cellular longevity 2023;2023:4654083
Oxidative medicine and cellular longevity 2023;2023:4654083
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
Ma Z, Wu J, Wu Y, Sun X, Rao Z, Sun N, Fu Y, Zhang Z, Li J, Xiao M, Zeng Q, Wu Y, Han C, Ding D, Zhang H, Yuan H, Zhang J, Yang S, Chen Y
International journal of biological sciences 2023;19(5):1633-1644
International journal of biological sciences 2023;19(5):1633-1644
TNFR2 deficiency impairs the growth of mouse colon cancer.
Li P, Yang Y, Yang X, Wang Y, Chou CK, Jiang M, Zheng J, Chen F, Chen X
International journal of biological sciences 2023;19(4):1024-1035
International journal of biological sciences 2023;19(4):1024-1035
Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration.
Xu WN, Liu C, Zheng HL, Xu HX, Yang RZ, Jiang SD, Zhu LX
International journal of biological sciences 2023;19(2):571-592
International journal of biological sciences 2023;19(2):571-592
Construction and validation of a prognostic signature based on necroptosis-related genes in hepatocellular carcinoma.
Peng YL, Wang LX, Li MY, Liu LP, Li RS
PloS one 2023;18(2):e0279744
PloS one 2023;18(2):e0279744
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Zhu X, Wang S, Cheng Y, Gu H, Zhang X, Teng M, Zhang Y, Wang J, Hua W, Lu X
Frontiers in neuroscience 2023;17:1174455
Frontiers in neuroscience 2023;17:1174455
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Duan J, Zhang Z, Du J, Zhang J, Li M, Li C
OncoTargets and therapy 2023;16:425-440
OncoTargets and therapy 2023;16:425-440
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway.
Ma J, Han Z, Jiao R, Yuan G, Ma C, Yan X, Meng A
Journal of inflammation research 2023;16:1045-1057
Journal of inflammation research 2023;16:1045-1057
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
C. tropicalis promotes CRC by down-regulating tumor cell-intrinsic PD-1 receptor via autophagy.
Qu J, Chen Q, Bing Z, Shen S, Hou Y, Lv M, Wang T
Journal of Cancer 2023;14(10):1794-1808
Journal of Cancer 2023;14(10):1794-1808
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Xiao T, Yu X, Yang L, Duan X
Frontiers in immunology 2023;14:1268467
Frontiers in immunology 2023;14:1268467
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling.
Wu L, Lin Y, Gao S, Wang Y, Pan H, Wang Z, Pozzolini M, Yang F, Zhang H, Yang Y, Xiao L, Xu Y
Frontiers in pharmacology 2023;14:1200843
Frontiers in pharmacology 2023;14:1200843
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
Echovirus induces autophagy to promote viral replication via regulating mTOR/ULK1 signaling pathway.
Wu C, Zeng L, Yi W, Miao Y, Liu Y, Wang Q, Liu S, Peng G, Zheng Z, Xia J
Frontiers in immunology 2023;14:1162208
Frontiers in immunology 2023;14:1162208
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Luo M, Chen Y, Pan X, Chen H, Fan L, Wen Y
Frontiers in immunology 2023;14:1137089
Frontiers in immunology 2023;14:1137089
Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma.
Qin H, Zheng G, Li Q, Shen L
Frontiers in pharmacology 2023;14:1128312
Frontiers in pharmacology 2023;14:1128312
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
Zhao S, Sun Y, Wu X, Yang Y, Fan K, Hu K, Qin Y, Li K, Lin L, Chen K, Ma Y, Zhu M, Liu G, Zhang L
Frontiers in pharmacology 2023;14:1092943
Frontiers in pharmacology 2023;14:1092943
SIRT6 drives sensitivity to ferroptosis in anaplastic thyroid cancer through NCOA4-dependent autophagy.
Yang Z, Huang R, Wang Y, Guan Q, Li D, Wu Y, Liao T, Wang Y, Xiang J
American journal of cancer research 2023;13(2):464-474
American journal of cancer research 2023;13(2):464-474
The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence.
Ayoubi R, Alshafie W, Shlaifer I, Southern K, McPherson PS, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group
F1000Research 2023;12:324
F1000Research 2023;12:324
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
Jiang S, Zheng J, Cui Z, Li Y, Wu Q, Cai X, Zheng C, Sun Y
Frontiers in cell and developmental biology 2023;11:1200197
Frontiers in cell and developmental biology 2023;11:1200197
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
He L, Li H, Li C, Liu ZK, Lu M, Zhang RY, Wu D, Wei D, Shao J, Liu M, Wei HL, Zhang C, Wang Z, Kong LM, Chen ZN, Bian H
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells.
Yu H, Hao Z, Liu X, Wei Z, Tan R, Liu X, Chen Q, Chen Y, Zhou H, Liu Y, Fu Z
Environmental toxicology 2023 Sep;38(9):2100-2110
Environmental toxicology 2023 Sep;38(9):2100-2110
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
Baicalin promotes random-pattern skin flap survival by inducing autophagy via AMPK-regulated TFEB nuclear transcription.
Zhang L, Yu G, Yu Q, Wang L, Wu L, Tao Z, Ding J, Lin D
Phytotherapy research : PTR 2023 Sep;37(9):3926-3938
Phytotherapy research : PTR 2023 Sep;37(9):3926-3938
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
Ma Y, Wu S, Zhao F, Li H, Li Q, Zhang J, Li H, Yuan Z
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Xu W, Hu Z, Tang Y, Zhang J, Xu S, Niu Q
Biological trace element research 2023 Sep;201(9):4472-4483
Biological trace element research 2023 Sep;201(9):4472-4483
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu J
Neurospine 2023 Sep;20(3):1011-1027
Neurospine 2023 Sep;20(3):1011-1027
NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity.
Wu T, Shao Y, Li X, Wu T, Yu L, Liang J, Zhang Y, Wang J, Sun T, Zhu Y, Chang X, Wang S, Chen F, Han X
Autophagy 2023 Sep;19(9):2538-2557
Autophagy 2023 Sep;19(9):2538-2557
CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.
Zhou Y, Liu Y, Kang Z, Yao H, Song N, Wang M, Song C, Zhang K, Ding J, Tang J, Hu G, Lu M
Autophagy 2023 Sep;19(9):2520-2537
Autophagy 2023 Sep;19(9):2520-2537
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Apatinib combined with olaparib induces ferroptosis via a p53-dependent manner in ovarian cancer.
Yue W, Yupeng G, Jun C, Kui J
Journal of cancer research and clinical oncology 2023 Sep;149(11):8681-8689
Journal of cancer research and clinical oncology 2023 Sep;149(11):8681-8689
Liensinine pretreatment reduces inflammation, oxidative stress, apoptosis, and autophagy to alleviate sepsis acute kidney injury.
Zhang W, Chen H, Xu Z, Zhang X, Tan X, He N, Shen J, Dong J
International immunopharmacology 2023 Sep;122:110563
International immunopharmacology 2023 Sep;122:110563
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
Spermidine alleviating oxidative stress and apoptosis by inducing autophagy of granulosa cells in Sichuan white geese.
Jiang D, Wang X, Zhou X, Wang Z, Li S, Sun Q, Jiang Y, Ji C, Ling W, An X, Kang B
Poultry science 2023 Sep;102(9):102879
Poultry science 2023 Sep;102(9):102879
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Chen J, Zheng D, Cai Z, Zhong B, Zhang H, Pan Z, Ling X, Han Y, Meng J, Li H, Chen X, Zhang H, Liu L
Toxics 2023 Sep 4;11(9)
Toxics 2023 Sep 4;11(9)
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Chen Q, Hu K, Shi J, Li H, Li W
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Zhou Q, Fang G, Pang Y, Wang X
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Sheng B, Wang W, Xia D, Qu X
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
Cancer/testis antigen CAGE mediates osimertinib resistance in non-small cell lung cancer cells and predicts poor prognosis in patients with pulmonary adenocarcinoma.
Yeon M, Lee H, Yeo J, Jeong MS, Jung HS, Lee H, Shim K, Jo H, Jeon D, Koh J, Jeoung D
Scientific reports 2023 Sep 21;13(1):15748
Scientific reports 2023 Sep 21;13(1):15748
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
Wang L, Cheng F, Pan R, Cui Z, She J, Zhang Y, Yang X
International journal of molecular sciences 2023 Sep 18;24(18)
International journal of molecular sciences 2023 Sep 18;24(18)
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Liu Y, Li Y, Tan Q, Lv Y, Tang Y, Yang Y, Yao X, Yang F
Toxins 2023 Sep 18;15(9)
Toxins 2023 Sep 18;15(9)
ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover.
Pu M, Zheng W, Zhang H, Wan W, Peng C, Chen X, Liu X, Xu Z, Zhou T, Sun Q, Neculai D, Liu W
Protein & cell 2023 Sep 14;14(9):653-667
Protein & cell 2023 Sep 14;14(9):653-667
Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers.
Yu L, Lv Z, Li S, Jiang H, Han B, Zheng X, Liu Y, Zhang Z
The Science of the total environment 2023 Sep 10;890:164172
The Science of the total environment 2023 Sep 10;890:164172
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation.
Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z
Journal of medical genetics 2023 Oct;60(10):939-950
Journal of medical genetics 2023 Oct;60(10):939-950
Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
Feng R, Liu J, Yang Z, Yao T, Ye P, Li X, Zhang J, Jiang H
Molecular neurobiology 2023 Oct;60(10):6001-6017
Molecular neurobiology 2023 Oct;60(10):6001-6017
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Guo Y, Zhang L
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Sorokolet K, Wilburn D, Bradley C, Papoutsi E, Wilkinson T, Ring A, Ferrer L, Haynatzki G, Smith RS, Bohannon WT, Koutakis P
Translational research : the journal of laboratory and clinical medicine 2023 Oct;260:17-31
Translational research : the journal of laboratory and clinical medicine 2023 Oct;260:17-31
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Yang Q, Zou Y, Wei X, Ye P, Wu Y, Ai H, Zhang Z, Tan J, Zhou J, Yang Y, Dai Q, Dou C, Luo F
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
Bu X, Zhang J, Sun H, Wang W, Ma X, Sun L
Journal of dental sciences 2023 Oct;18(4):1685-1692
Journal of dental sciences 2023 Oct;18(4):1685-1692
The adhesion G protein-coupled receptor VLGR1/ADGRV1 controls autophagy.
Linnert J, Güler BE, Krzysko J, Wolfrum U
Basic & clinical pharmacology & toxicology 2023 Oct;133(4):313-330
Basic & clinical pharmacology & toxicology 2023 Oct;133(4):313-330
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells.
Zhou M, Boulos JC, Omer EA, Rudbari HA, Schirmeister T, Micale N, Efferth T
European journal of pharmacology 2023 Oct 5;956:175980
European journal of pharmacology 2023 Oct 5;956:175980
Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling.
Chai L, Wang Q, Wang Y, Li D, Zhang Q, Chen Y, Liu J, Chen H, Qiu Y, Shen N, Wang J, Xie X, Li M
European journal of pharmacology 2023 Oct 5;956:175968
European journal of pharmacology 2023 Oct 5;956:175968
TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.
Yao W, Chen Y, Chen Y, Zhao P, Liu J, Zhang Y, Jiang Q, Wu C, Xie Y, Fan S, Ye M, Wang Y, Feng Y, Bai X, Fan M, Feng S, Wang J, Cui Y, Xia H, Ma C, Xie Z, Zhang L, Sun Q, Liu W, Yi C
The EMBO journal 2023 Oct 4;42(19):e112814
The EMBO journal 2023 Oct 4;42(19):e112814
Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Tsioras K, Smith KC, Edassery SL, Garjani M, Li Y, Williams C, McKenna ED, Guo W, Wilen AP, Hark TJ, Marklund SL, Ostrow LW, Gilthorpe JD, Ichida JK, Kalb RG, Savas JN, Kiskinis E
Cell reports 2023 Oct 31;42(10):113160
Cell reports 2023 Oct 31;42(10):113160
Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration.
Ren C, Cui H, Bao X, Huang L, He S, Fong HKW, Zhao M
Investigative ophthalmology & visual science 2023 Oct 3;64(13):41
Investigative ophthalmology & visual science 2023 Oct 3;64(13):41
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Gao Y, Lu LJ, Zhang ZZ, Yang X, Du J, Wen K, Huang H, Wang XP, Sun XL
Journal of ethnopharmacology 2023 Oct 28;315:116678
Journal of ethnopharmacology 2023 Oct 28;315:116678
Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin-Angiotensin System in Mice.
Yi X, Xu C, Yang J, Zhong C, Yang H, Tang L, Song S, Yu J
International journal of molecular sciences 2023 Oct 25;24(21)
International journal of molecular sciences 2023 Oct 25;24(21)
Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction.
Zhang C, Duan Y, Huang C, Li L
Cellular & molecular biology letters 2023 Oct 24;28(1):85
Cellular & molecular biology letters 2023 Oct 24;28(1):85
Visual impairment cell non-autonomously dysregulates brain-wide proteostasis.
Shekhar S, Wert KJ, Krämer H
bioRxiv : the preprint server for biology 2023 Oct 23;
bioRxiv : the preprint server for biology 2023 Oct 23;
Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease.
Wang X, Xie Y, Chen G, Lu Y, Wang D, Zhu L
Journal of neuroinflammation 2023 Oct 20;20(1):240
Journal of neuroinflammation 2023 Oct 20;20(1):240
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Liu C, Lu C, Yixi L, Hong J, Dong F, Ruan S, Hu T, Zhao X
Breast cancer research : BCR 2023 Oct 17;25(1):124
Breast cancer research : BCR 2023 Oct 17;25(1):124
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Cadmium induces apoptosis of mouse spermatocytes through JNK activation and disruption of autophagic flux.
Zhou L, Chen Y, Sun Y, Li N, Liu Y, Tan W, Zhang L
Ecotoxicology and environmental safety 2023 Oct 15;265:115505
Ecotoxicology and environmental safety 2023 Oct 15;265:115505
Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia.
Bressan C, Snapyan M, Snapyan M, Klaus J, di Matteo F, Robertson SP, Treutlein B, Parent M, Cappello S, Saghatelyan A
EMBO molecular medicine 2023 Oct 11;15(10):e16908
EMBO molecular medicine 2023 Oct 11;15(10):e16908
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
Wang L, Song R, Ma M, Chen Y, Jiang Y, Li J, Yang Z, Zhang L, Jing M, Wang X, Zhang M, Fan J
Chemico-biological interactions 2023 Oct 1;384:110725
Chemico-biological interactions 2023 Oct 1;384:110725
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Zhang T, Bai J, Chen G, Chen Z, Zeng S, Yang Y, Wu Z
Chemico-biological interactions 2023 Oct 1;384:110695
Chemico-biological interactions 2023 Oct 1;384:110695
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Differential regulation of autophagy on urine-concentrating capability through modulating the renal AQP2 expression and renin-angiotensin system in mice.
Xu C, Yi X, Tang L, Wang H, Chu S, Yu J
American journal of physiology. Renal physiology 2023 Oct 1;325(4):F503-F518
American journal of physiology. Renal physiology 2023 Oct 1;325(4):F503-F518
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Hu H, Wang Y, Dong Y, Wang L, Chen Y, Zhou Y, Sun L
Molecular biology reports 2023 Nov;50(11):8985-8993
Molecular biology reports 2023 Nov;50(11):8985-8993
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Lian N, Tong J, Zhu W, Meng Q, Jiang M, Bian M, Li Y
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
Boulos JC, Omer EA, Rigano D, Formisano C, Chatterjee M, Leich E, Klauck SM, Shan LT, Efferth T
Acta pharmacologica Sinica 2023 Nov;44(11):2265-2281
Acta pharmacologica Sinica 2023 Nov;44(11):2265-2281
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W
Oncogene 2023 Nov;42(45):3331-3343
Oncogene 2023 Nov;42(45):3331-3343
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Liu H, He Y, Gao X, Li T, Qiao B, Tang L, Lan J, Su Q, Ruan Z, Tang Z, Hu L
Mycotoxin research 2023 Nov;39(4):437-451
Mycotoxin research 2023 Nov;39(4):437-451
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Yan Y, Yu S, Fan Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages.
Jiang K, Li J, Jiang L, Li H, Lei L
Oral diseases 2023 Nov;29(8):3665-3676
Oral diseases 2023 Nov;29(8):3665-3676
Plasma metabonomic study on the effect of Para‑hydroxybenzaldehyde intervention in a rat model of transient focal cerebral ischemia.
Yu X, Luo Y, Yang L, Duan X
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage.
Li D, Wang L, Zhao Z, Bai C, Li X
Immunology letters 2023 Nov;263:25-32
Immunology letters 2023 Nov;263:25-32
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
Wenhao R, Yali C, Shaoming L, Jingjing Z, Ling G, Keqian Z
Journal of cellular physiology 2023 Nov;238(11):2612-2624
Journal of cellular physiology 2023 Nov;238(11):2612-2624
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
Lu J, Chen Z, Bu X, Chen S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
Hu H, Lin G, He F, Liu J, Jia R, Li K, Hong W, Fang M, Zeng JZ
Bioorganic chemistry 2023 Nov;140:106795
Bioorganic chemistry 2023 Nov;140:106795
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Xiao C, Sun Y, Fan J, Nguyen W, Chen S, Long Y, Chen W, Zhu A, Liu B
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Activation of Nrf2/ARE pathway by Anisodamine (654-2) for Inhibition of cellular aging and alleviation of Radiation-Induced lung injury.
Guo H, Chen J, Yu H, Dong L, Yu R, Li Q, Song J, Chen H, Zhang H, Pu J, Wang W
International immunopharmacology 2023 Nov;124(Pt A):110864
International immunopharmacology 2023 Nov;124(Pt A):110864
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
Wang Q, Jiang Y, Bao G, Yao W, Yang Q, Chen S, Wang G
Veterinary research 2023 Nov 7;54(1):103
Veterinary research 2023 Nov 7;54(1):103
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Wang Y, Xu Y, Wang Q, Guo F, Song Y, Fan X, Shao M, Chen D, Zhang W, Qin G
European journal of pharmacology 2023 Nov 5;958:176042
European journal of pharmacology 2023 Nov 5;958:176042
Six-hour time-restricted feeding inhibits lung cancer progression and reshapes circadian metabolism.
Shi D, Fang G, Chen Q, Li J, Ruan X, Lian X
BMC medicine 2023 Nov 3;21(1):417
BMC medicine 2023 Nov 3;21(1):417
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Peroxiredoxin 1 regulates crosstalk between pyroptosis and autophagy in oral squamous cell carcinoma leading to a potential pro-survival.
Ye M, Liu T, Liu S, Tang R, Liu H, Zhang F, Luo S, Li M
Cell death discovery 2023 Nov 25;9(1):425
Cell death discovery 2023 Nov 25;9(1):425
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Xu ST, Zhang YX, Liu SL, Liu F, Ye JT
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Zhang X, Dong Z, Yang Y, Liu C, Li J, Sun W, Zhu Y, Shen Y, Wang Z, Lü M, Cui H
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells.
Su AL, Tian CQ, Ou YJ, Bao XB, Huan XJ, Miao ZH, Wang YQ
Life sciences 2023 Nov 1;332:122129
Life sciences 2023 Nov 1;332:122129
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Liu J, Zhu Q, Pan Y, Hao S, Wang Z, Cui C, Li J, Huang Y, Xia L, Xu T, Cheng J, Shen J, Xia Y
Molecular human reproduction 2023 Nov 1;29(11)
Molecular human reproduction 2023 Nov 1;29(11)
Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice.
Zhao H, Dan P, Xi J, Chen Z, Zhang P, Wei W, Zhao Y
International journal of biological macromolecules 2023 Nov 1;251:126347
International journal of biological macromolecules 2023 Nov 1;251:126347
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Zhou F, Li X, Jia K, Li F, Xue X, Liu J, Qu J, Liu R
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
Modulation of virus-induced neuroinflammation by the autophagy receptor SHISA9 in mice.
Zheng Y, Wang L, Liu Q, Xian H, Zhang C, Cai S, Yang S, Jin S, Cui J
Nature microbiology 2023 May;8(5):958-972
Nature microbiology 2023 May;8(5):958-972
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S
Redox biology 2023 May;61:102635
Redox biology 2023 May;61:102635
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Xiao Z, Li M, Zhang X, Rong X, Xu H
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats.
Guan T, Xiao Y, Xie X, Meng N, Qi Q, Xu J, Jiang X, Zhang Z, Teng Z, Lv P
Neurochemical research 2023 May;48(5):1561-1579
Neurochemical research 2023 May;48(5):1561-1579
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Guo Y, Cui Y, Li Y, Jin X, Wang D, Lei M, Chen F, Liu Y, Xu J, Yao G, Zeng G, Chen X
Cancer communications (London, England) 2023 May;43(5):582-612
Cancer communications (London, England) 2023 May;43(5):582-612
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
Yan G, Yang J, Li W, Guo A, Guan J, Liu Y
Nature cell biology 2023 May;25(5):754-764
Nature cell biology 2023 May;25(5):754-764
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
Ma Z, Bai J, Jiang C, Zhu H, Liu D, Pan M, Wang X, Pi J, Jiang P, Liu X
Autophagy 2023 May;19(5):1512-1532
Autophagy 2023 May;19(5):1512-1532
Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression.
Yao H, Li J, Liu Z, Ouyang C, Qiu Y, Zheng X, Mu J, Xie Z
Autophagy 2023 May;19(5):1491-1511
Autophagy 2023 May;19(5):1491-1511
Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53.
Zhang Y, Guo T, Li S, Ren Z, Gao S, Lu H, Ma X, Liu D, Liu Y, Kong D, Qiu Y
Discover oncology 2023 May 31;14(1):84
Discover oncology 2023 May 31;14(1):84
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389
Scientific reports 2023 May 24;13(1):8389
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Zhang X, Wang S, Jin Y, Wang J, Wang R, Yang X, Zhang S, Yan T, Jia Y
Journal of ethnopharmacology 2023 May 23;308:116253
Journal of ethnopharmacology 2023 May 23;308:116253
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Wu J, Subbaiah KCV, Hedaya O, Chen S, Munger J, Tang WHW, Yan C, Yao P
bioRxiv : the preprint server for biology 2023 May 22;
bioRxiv : the preprint server for biology 2023 May 22;
Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis.
Dai S, Liu M, Liu M, Jiang C, Yang Y, Han H, Yang Y, Jiang X, Shen Y
Human molecular genetics 2023 May 18;32(11):1814-1825
Human molecular genetics 2023 May 18;32(11):1814-1825
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Zhang L, Yang G, Wang J, Zhang J, Chen K, Xiong X, Zhu Y, Xu C, Wang J
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Meng Z, Gao M, Wang C, Guan S, Zhang D, Lu J
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Xia C, Wang G, Chen L, Geng H, Yao J, Bai Z, Deng L
Cell proliferation 2023 Mar;56(3):e13360
Cell proliferation 2023 Mar;56(3):e13360
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
Liu F, Li M
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Lu R, Xu H, Deng X, Wang Y, He Z, Xu S, Liang S, Huang X, You H, Guo F, Cheng P, Chen AM
Journal of orthopaedic translation 2023 Mar;39:74-87
Journal of orthopaedic translation 2023 Mar;39:74-87
Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR.
Ren J, Hu Z, Niu G, Xia J, Wang X, Hong R, Gu J, Wang D, Ke C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22790
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22790
P‑hydroxybenzyl alcohol ameliorates neuronal cerebral ischemia‑reperfusion injury by activating mitochondrial autophagy through SIRT1.
Yu X, Luo Y, Yang L, Chen P, Duan X
Molecular medicine reports 2023 Mar;27(3)
Molecular medicine reports 2023 Mar;27(3)
MiR-141-3p promotes hypoxia-induced autophagy in human placental trophoblast cells.
Luo Q, Tian Y, Qu G, Huang K, Hu P, Li L, Luo S
Reproductive biology 2023 Mar;23(1):100712
Reproductive biology 2023 Mar;23(1):100712
Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models.
Lu H, Liu Z, Deng X, Chen S, Zhou R, Zhao R, Parandaman R, Thind A, Henley J, Tian L, Yu J, Comai L, Feng P, Yuan W
PLoS pathogens 2023 Mar;19(3):e1011240
PLoS pathogens 2023 Mar;19(3):e1011240
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857
Autophagy 2023 Mar;19(3):839-857
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Yang J, Hasenbilige, Bao S, Luo S, Jiang L, Li Q, Kong Y, Cao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C, Lu T, Liu M, Yuan X, Li D, Zhang J, Zhou L, Xu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Zhang M, Li L, Li S, Liu Z, Zhang N, Sun B, Wang Z, Jia D, Liu M, Wang Q
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Gai C, Zhao Y, Xin D, Li T, Cheng Y, Jiang Z, Song Y, Liu D, Wang Z
Cells 2023 Mar 9;12(6)
Cells 2023 Mar 9;12(6)
Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
Yuan G, Xu Y, Bai X, Wang W, Wu X, Chen J, Li J, Jia X, Gu Z, Zhang X, Hu W, Wang J, Liu Y, Zhu XM
ACS applied materials & interfaces 2023 Mar 8;15(9):11431-11443
ACS applied materials & interfaces 2023 Mar 8;15(9):11431-11443
Aqueous extract of Sanghuangporus baumii induces autophagy to inhibit cervical carcinoma growth.
Wu D, Yuan X, Zhou R, Chen W, Li W, Li Z, Li X, Zhu R, Wang H, Yang Y
Food & function 2023 Mar 6;14(5):2374-2384
Food & function 2023 Mar 6;14(5):2374-2384
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Pei X, Liu D, Li J, Li L, Ding X, Zhang W, Li Z, Xu G, Li C, Li D
The Science of the total environment 2023 Mar 20;865:161242
The Science of the total environment 2023 Mar 20;865:161242
A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ERα degradation and the autophagy-lysosome pathway.
Zhou J, Shen R, Liu J, Deng X, Xin L, Zhou HB, Huang J
Bioorganic & medicinal chemistry 2023 Mar 15;82:117235
Bioorganic & medicinal chemistry 2023 Mar 15;82:117235
YTHDF2 controls hexavalent chromium-induced mitophagy through modulating Hif1α and Bnip3 decay via the m(6)A/mRNA pathway in spermatogonial stem cells/progenitors.
Li T, Zheng Y, Wu Z, Guo M, Liu R, Zeng W, Lv Y
Toxicology letters 2023 Mar 15;377:38-50
Toxicology letters 2023 Mar 15;377:38-50
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Hu Z, Xu W, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Pre-ischaemic Treatment with Enriched Environment Alleviates Acute Neuronal Injury by Inhibiting Endoplasmic Reticulum Stress-dependent Autophagy and Apoptosis.
Han Y, Shen XY, Gao ZK, Ping Han P, Bi X
Neuroscience 2023 Mar 1;513:14-27
Neuroscience 2023 Mar 1;513:14-27
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
Zheng R, Yu Y, Lv L, Zhang Y, Deng H, Li J, Zhang B
Experimental cell research 2023 Mar 1;424(1):113487
Experimental cell research 2023 Mar 1;424(1):113487
YAP1 suppression inhibits autophagy and improves the efficacy of anti-PD-1 immunotherapy in hepatocellular carcinoma.
Gao Y, Peng Q, Li S, Zheng K, Gong Y, Xue Y, Liu Y, Lu J, Zhang Y, Shi X
Experimental cell research 2023 Mar 1;424(1):113486
Experimental cell research 2023 Mar 1;424(1):113486
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Zhang H, Xie Z, Peng Y, Xie A, Fu C, Zheng D, Cai Z, Zhong J, Ming Q, Li M, Lu R, Liu X, Chen J
Ecotoxicology and environmental safety 2023 Mar 1;252:114630
Ecotoxicology and environmental safety 2023 Mar 1;252:114630
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Liu X, Xi H, Han S, Zhang H, Hu J
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Ecotoxicology and environmental safety 2023 Mar 1;252:114571
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Ge W, Luo S, Zhang K, Liu L, Zhou Z, Liu Y
Tissue & cell 2023 Jun;82:102113
Tissue & cell 2023 Jun;82:102113
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Ursolic acid nanoparticles for glioblastoma therapy.
Li Y, Zhao L, Zhao Q, Zhou Y, Zhou L, Song P, Liu B, Chen Q, Deng G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Li ZB, Jiang L, Ni JD, Xu YH, Liu F, Liu WM, Wang SG, Liu ZQ, Wang CY
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Wei Y, Sun L, Liu C, Li L
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2023 Jun;39(3):729-749
Cell biology and toxicology 2023 Jun;39(3):729-749
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Wang P, Zheng SY, Jiang RL, Wu HD, Li YA, Lu JL, Xiong Y, Han B, Lin L
Free radical biology & medicine 2023 Jun;202:76-96
Free radical biology & medicine 2023 Jun;202:76-96
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Deng H, Chen W, Zhang B, Zhang Y, Han L, Zhang Q, Yao S, Wang H, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure.
Piell KM, Petri BJ, Head KZ, Wahlang B, Xu R, Zhang X, Pan J, Rai SN, de Silva K, Chariker JH, Rouchka EC, Tan M, Li Y, Cave MC, Klinge CM
Environmental toxicology and pharmacology 2023 Jun;100:104138
Environmental toxicology and pharmacology 2023 Jun;100:104138
CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP-43 and Encoding A Novel TMEFF1-339aa Protein.
Chen R, Yang T, Jin B, Xu W, Yan Y, Wood N, Lehmann HI, Wang S, Zhu X, Yuan W, Chen H, Liu Z, Li G, Bowen TS, Li J, Xiao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206732
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206732
Mitochondrial damage-induced abnormal glucose metabolism with ageing in the hippocampus of APP/PS1 mice.
Li S, Wang Y, Zhang X, Xiong X, Zhou F, Li X, Fan J, Liang X, Li G, Peng Y, Li Y
Metabolomics : Official journal of the Metabolomic Society 2023 Jun 8;19(6):56
Metabolomics : Official journal of the Metabolomic Society 2023 Jun 8;19(6):56
RETRACTED: Tangzhiqing-mediated NRF2 reduces autophagy-dependent ferroptosis to mitigate diabetes-related cognitive impairment neuronal damage.
Qiu L, Chen K, Wang X, Zhao Y
Rejuvenation research 2023 Jun 6;
Rejuvenation research 2023 Jun 6;
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Wang C, Liu T, Wang J, Cheng C, Zhang Z, Zhang J, Huang H, Li Y
Discover oncology 2023 Jun 3;14(1):86
Discover oncology 2023 Jun 3;14(1):86
miR-210 promotes hepatocellular carcinoma progression by modulating macrophage autophagy through PI3K/AKT/mTOR signaling.
Bi S, Zhang Y, Zhou J, Yao Y, Wang J, Fang M, Li B, Wu C, Ren C
Biochemical and biophysical research communications 2023 Jun 25;662:47-57
Biochemical and biophysical research communications 2023 Jun 25;662:47-57
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Chen Z, Chen H, Huang L, Duan B, Dai S, Cai W, Sun M, Jiang Z, Lu R, Jiang Y, Jiang X, Zheng H, Yao Q, Kim K, Lin G, Xie C, Chu M, Chen R, Kou L
International journal of pharmaceutics 2023 Jun 25;641:123082
International journal of pharmaceutics 2023 Jun 25;641:123082
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
Tong Y, Zhu W, Chen J, Wen T, Xu F, Pang J
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, Zhang L, Qian Y, Sun Y, Wang A, Zou Y, Chen W, Li Y, Huang L, Yang Y, Zhao Y, Cheng X
Science advances 2023 Jun 2;9(22):eadg4993
Science advances 2023 Jun 2;9(22):eadg4993
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
Yao X, Liu Y, Yang Y, Li Y, Hu N, Song F, Yang F
Toxins 2023 Jun 19;15(6)
Toxins 2023 Jun 19;15(6)
Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway.
Liu H, Zhou Z, Deng H, Tian Z, Wu Z, Liu X, Ren Z, Jiang Z
European journal of pharmacology 2023 Jun 15;949:175735
European journal of pharmacology 2023 Jun 15;949:175735
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Wu J, Deng F, Tang X, Chen W, Zhou R, Zhao T, Mao X, Shu F
Journal of hazardous materials 2023 Jun 15;452:131234
Journal of hazardous materials 2023 Jun 15;452:131234
USP1-Associated Factor 1 Modulates Japanese Encephalitis Virus Replication by Governing Autophagy and Interferon-Stimulated Genes.
Xing J, Hu C, Che S, Lan Y, Huang L, Liu L, Yin Y, Li H, Liao M, Qi W
Microbiology spectrum 2023 Jun 15;11(3):e0318622
Microbiology spectrum 2023 Jun 15;11(3):e0318622
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
Feng C, Liu Y, Zhang BY, Zhang H, Shan FY, Li TQ, Zhao ZN, Wang XX, Zhang XY
ACS omega 2023 Jun 13;8(23):20739-20754
ACS omega 2023 Jun 13;8(23):20739-20754
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.
Farris LC, Torres-Odio S, Adams LG, West AP, Hyde JA
Journal of immunology (Baltimore, Md. : 1950) 2023 Jun 1;210(11):1761-1770
Journal of immunology (Baltimore, Md. : 1950) 2023 Jun 1;210(11):1761-1770
Impairment of autophagy promotes human conjunctival fibrosis and pterygium occurrence via enhancing the SQSTM1-NF-κB signaling pathway.
He Q, Cai Y, Huang J, He X, Han W, Chen W
Journal of molecular cell biology 2023 Jun 1;15(1)
Journal of molecular cell biology 2023 Jun 1;15(1)
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
Lin Q, Liu T, Wang X, Hou G, Xiang Z, Zhang W, Zheng S, Zhao D, Leng Q, Zhang X, Lu M, Guan T, Liu H, Hu Y
The Journal of clinical investigation 2023 Jun 1;133(11)
The Journal of clinical investigation 2023 Jun 1;133(11)
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Li H, Wei Y, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Hao J
Acta cardiologica 2023 Jul;78(5):594-606
Acta cardiologica 2023 Jul;78(5):594-606
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336
Advanced biology 2023 Jul;7(7):e2200336
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X
Redox biology 2023 Jul;63:102732
Redox biology 2023 Jul;63:102732
Homoplantaginin attenuates high glucose-induced vascular endothelial cell apoptosis through promoting autophagy via the AMPK/TFEB pathway.
Fan L, Zhang X, Huang Y, Zhang B, Li W, Shi Q, Lin Y, Wu F
Phytotherapy research : PTR 2023 Jul;37(7):3025-3041
Phytotherapy research : PTR 2023 Jul;37(7):3025-3041
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Zhang LC, Liu YN, La XQ, Li ST, Wen LN, Liu T, Li HQ, Li AP, Wu H, Wu CX, Li ZY
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Li D, Li Z, Dong L, Zhang Y, Lu Y, Wang J, Sun H, Wang S
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Ding M, Zhou F, Li Y, Liu C, Gu Y, Wu J, Fan G, Li Y, Li X
Chinese herbal medicines 2023 Jul;15(3):421-429
Chinese herbal medicines 2023 Jul;15(3):421-429
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Wang Y, Chen YY, Gao GB, Zheng YH, Yu NN, Ouyang L, Gao X, Li N, Wen SY, Huang S, Zhao Q, Liu L, Cao M, Zhang S, Zhang J, He QY
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice.
Chen F, Zhan J, Al Mamun A, Tao Y, Huang S, Zhao J, Zhang Y, Xu Y, Du S, Lu W, Li X, Chen Z, Xiao J
Food & function 2023 Jul 31;14(15):7176-7194
Food & function 2023 Jul 31;14(15):7176-7194
Proteomics of Plasma and Plasma-Treated Podocytes: Application to Focal and Segmental Glomerulosclerosis.
Chhuon C, Herrera-Marcos LV, Zhang SY, Charrière-Bertrand C, Jung V, Lipecka J, Savas B, Nasser N, Pawlak A, Boulmerka H, Audard V, Sahali D, Guerrera IC, Ollero M
International journal of molecular sciences 2023 Jul 28;24(15)
International journal of molecular sciences 2023 Jul 28;24(15)
Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells.
Zhou M, Boulos JC, Omer EA, Klauck SM, Efferth T
Molecules (Basel, Switzerland) 2023 Jul 26;28(15)
Molecules (Basel, Switzerland) 2023 Jul 26;28(15)
ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway.
Sun RX, Zhu HJ, Zhang YR, Wang JN, Wang Y, Cao QC, Ji JD, Jiang C, Yuan ST, Chen X, Liu QH
Cell reports 2023 Jul 25;42(7):112779
Cell reports 2023 Jul 25;42(7):112779
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
Lloyd GM, Long B, Quintin S, Sorrentino ZA, Gorion KM, Bell BM, Carrillo D, Sullivan P, Borchelt D, Giasson BI
Acta neuropathologica communications 2023 Jul 23;11(1):119
Acta neuropathologica communications 2023 Jul 23;11(1):119
Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe(3)O(4) in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway.
Li Y, Liu T, Li X, Yang M, Liu T, Bao J, Jiang M, Hu L, Wang Y, Shao P, Jiang J
Aging 2023 Jul 19;15(14):6933-6949
Aging 2023 Jul 19;15(14):6933-6949
Cold exposure protects against medial arterial calcification development via autophagy.
Li FX, Liu JJ, Xu F, Shan SK, Zheng MH, Lei LM, Lin X, Guo B, Li CC, Wu F, Tang KX, Cao YC, Wu YY, Duan JY, Wu YL, He SY, Chen X, Yuan LQ
Journal of nanobiotechnology 2023 Jul 17;21(1):226
Journal of nanobiotechnology 2023 Jul 17;21(1):226
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Chu F, Wu P, Mu M, Hu S, Niu C
Cell death & disease 2023 Jul 17;14(7):443
Cell death & disease 2023 Jul 17;14(7):443
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
Liu X, Li H, Wang T, Yang T, Yang X, Guo K, Hu L, Ming J
International journal of biological macromolecules 2023 Jul 15;243:125130
International journal of biological macromolecules 2023 Jul 15;243:125130
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex.
Kurusu R, Fujimoto Y, Morishita H, Noshiro D, Takada S, Yamano K, Tanaka H, Arai R, Kageyama S, Funakoshi T, Komatsu-Hirota S, Taka H, Kazuno S, Miura Y, Koike M, Wakai T, Waguri S, Noda NN, Komatsu M
Developmental cell 2023 Jul 10;58(13):1189-1205.e11
Developmental cell 2023 Jul 10;58(13):1189-1205.e11
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner.
Wang L, Li D, Su X, Zhao Y, Huang A, Li H, Li J, Xia W, Jia T, Zhang H, Dong J, Liu X, Shao N
Oncogene 2023 Jan;42(1):62-77
Oncogene 2023 Jan;42(1):62-77
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Xu X, Feng Y, Han C, Yao Z, Liu Y, Luo C, Sheng J
Environmental toxicology 2023 Jan;38(1):205-215
Environmental toxicology 2023 Jan;38(1):205-215
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
Lv M, Qian X, Li S, Gong J, Wang Q, Qian Y, Su Z, Xue X, Liu HK
Journal of inorganic biochemistry 2023 Jan;238:112057
Journal of inorganic biochemistry 2023 Jan;238:112057
SIRT3 attenuates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome via autophagy.
Sun Z, Fang C, Xu S, Wang B, Li D, Liu X, Mi Y, Guo H, Jiang J
Biochemical pharmacology 2023 Jan;207:115354
Biochemical pharmacology 2023 Jan;207:115354
Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia.
Lin Y, Zhan Z, Hu M, Li H, Zhang B, Wu R, Tan S, Shan Y, Lu Z, Qin B
Journal of neurochemistry 2023 Jan;164(2):172-192
Journal of neurochemistry 2023 Jan;164(2):172-192
Berberine enhances autophagic flux by activating the Nrf2 signaling pathway in bovine endometrial epithelial cells to resist LPS-induced apoptosis.
Fu K, Chen H, Mei L, Wang J, Gong B, Li Y, Cao R
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13847
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13847
Ischemic Stroke Induces Skeletal Muscle Damage and Alters Transcriptome Profile in Rats.
Qi H, Li X, Zhang X, Li B, Tian D, Wang D, Yang R, Zeng N
Journal of clinical medicine 2023 Jan 9;12(2)
Journal of clinical medicine 2023 Jan 9;12(2)
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4.
Luo S, Zhang C, Gao Z, Jiang L, Li Q, Shi X, Kong Y, Cao J
Chemico-biological interactions 2023 Jan 5;369:110293
Chemico-biological interactions 2023 Jan 5;369:110293
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis.
Lei C, Huo Y, Ma F, Liao J, Hu Z, Han Q, Li Y, Pan J, Hu L, Guo J, Tang Z
Chemico-biological interactions 2023 Jan 5;369:110256
Chemico-biological interactions 2023 Jan 5;369:110256
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Chen F, Song C, Meng F, Zhu Y, Chen X, Fang X, Ma D, Wang Y, Zhang C
International journal of biological macromolecules 2023 Jan 31;226:397-409
International journal of biological macromolecules 2023 Jan 31;226:397-409
EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis.
Liu B, Zhou Y, Wu Q, Fu Y, Zhang X, Wang Z, Yi W, Wang H, Chen Z, Song Z, Xiong W, Qiu Y, He W, Ju Z
Cell death & disease 2023 Jan 30;14(1):71
Cell death & disease 2023 Jan 30;14(1):71
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Meng Z, Lu J, Ge G, Wang G, Zhang R, Li Y, Guan S, Lu J
Food & function 2023 Jan 3;14(1):240-249
Food & function 2023 Jan 3;14(1):240-249
Effects of exogenous spermidine on autophagy and antioxidant capacity in ovaries and granulosa cells of Sichuan white geese.
Jiang D, Sun Q, Jiang Y, Zhou X, Kang L, Wang Z, Wang X, An X, Ji C, Ling W, Wang Y, Yang Y, Kang B
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Sun H, Wang Z, Zhang Q, Chen N, Tang M, Yang Z, Xu Y, Kang J, Wang Y
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis.
Long X, Liu X, Deng T, Chen J, Lan J, Zhang S, Zhou M, Guo D, Zhou J
Journal of experimental & clinical cancer research : CR 2023 Jan 24;42(1):33
Journal of experimental & clinical cancer research : CR 2023 Jan 24;42(1):33
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Li Q, Fan J, Chen Y, Liu Y, Liu H, Jiang W, Li D, Dang Y
Marine drugs 2023 Jan 20;21(2)
Marine drugs 2023 Jan 20;21(2)
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Zhang J, Tang Y, Hu Z, Xu W, Ma Y, Xu P, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Xu W, Hu Z, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Design, synthesis and anti-ovarian cancer activities of thieno[2,3-d]pyrimidine based chimeric BRD4 inhibitor/nitric oxide-donator.
Zhang Y, Pan Z, Chen C, Tan Y, Wang X, Wang L, Zhang L, Chen Y, He G
European journal of medicinal chemistry 2023 Jan 15;246:114970
European journal of medicinal chemistry 2023 Jan 15;246:114970
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
Huang PH, Duan XB, Tang ZZ, Zou ZX, Song WM, Gao G, Li D, Nie FQ, Yan X, Fu YX, Guo R, Xu YY
Scientific reports 2023 Jan 13;13(1):743
Scientific reports 2023 Jan 13;13(1):743
LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers.
Ma M, Cai B, Zhou Z, Kong S, Zhang J, Xu H, Zhang X, Nie Q
Cell communication and signaling : CCS 2023 Jan 12;21(1):7
Cell communication and signaling : CCS 2023 Jan 12;21(1):7
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Xi H, Hu Z, Han S, Liu X, Wang L, Hu J
Theriogenology 2023 Jan 1;195:103-114
Theriogenology 2023 Jan 1;195:103-114
Targeting Annexin A1 as a Druggable Player to Enhance the Anti-Tumor Role of Honokiol in Colon Cancer through Autophagic Pathway.
Wang X, Shao G, Hong X, Shi Y, Zheng Y, Yu Y, Fu C
Pharmaceuticals (Basel, Switzerland) 2023 Jan 1;16(1)
Pharmaceuticals (Basel, Switzerland) 2023 Jan 1;16(1)
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Zhang T, Yang K, Chen Y, Jiang Y, Zhou Z, Liu J, Du Y, Wang L, Han X, Wu X, Wang X
Journal of periodontal research 2023 Feb;58(1):70-82
Journal of periodontal research 2023 Feb;58(1):70-82
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2023 Feb;39(1):259-275
Cell biology and toxicology 2023 Feb;39(1):259-275
N(6)-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Gao Z, Li C, Sun H, Bian Y, Cui Z, Wang N, Wang Z, Yang Y, Liu Z, He Z, Li B, Li F, Li Z, Wang L, Zhang D, Yang L, Xu Z, Li X, Xu H
Cell death and differentiation 2023 Feb;30(2):544-559
Cell death and differentiation 2023 Feb;30(2):544-559
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Zhang G, Jiang C, Yang Y, Wang Y, Zhou H, Dai S, Liu M, Yang Y, Yang L, Shen Q, Zhang T, Zhang X, Yang Y, Shen Y
Cell death and differentiation 2023 Feb;30(2):500-514
Cell death and differentiation 2023 Feb;30(2):500-514
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers.
Zheng S, Wang X, Liu H, Zhao D, Lin Q, Jiang Q, Li L, Hu Y
Cell death and differentiation 2023 Feb;30(2):327-340
Cell death and differentiation 2023 Feb;30(2):327-340
Combination of a New Oral Demethylating Agent, OR2100, and Venetoclax for Treatment of Acute Myeloid Leukemia.
Kamachi K, Ureshino H, Watanabe T, Yoshida-Sakai N, Fukuda-Kurahashi Y, Kawasoe K, Hoshiko T, Yamamoto Y, Kurahashi Y, Kimura S
Cancer research communications 2023 Feb;3(2):297-308
Cancer research communications 2023 Feb;3(2):297-308
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
Zhang X, Li S, Ren X, Xiang P, Zhang Y, Wang T, Qin Q, Sun F, Liu J, Gao L, Ma C, Yue X, Yang X, Han S, Liang X
The FEBS journal 2023 Feb;290(4):1117-1133
The FEBS journal 2023 Feb;290(4):1117-1133
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Zhang B, Li H, Wang Y, Li Y, Zhou Z, Hou X, Zhang X, Liu T
Ecotoxicology and environmental safety 2023 Feb;251:114557
Ecotoxicology and environmental safety 2023 Feb;251:114557
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Li B, Li W, Zheng M, Wang Y, Diao Y, Mou X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
Qin S, Wang G, Chen L, Geng H, Zheng Y, Xia C, Wu S, Yao J, Deng L
PLoS genetics 2023 Feb;19(2):e1010629
PLoS genetics 2023 Feb;19(2):e1010629
Apilimod enhances specific productivity in recombinant CHO cells through cell cycle arrest and mediation of autophagy.
Lu JT, Xiao MK, Feng YY, Wang XY, Qiu LL, Chai YR, Wang TY, Jia YL
Biotechnology journal 2023 Feb;18(2):e2200147
Biotechnology journal 2023 Feb;18(2):e2200147
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Inoue M, Noguchi S, Inoue YU, Iida A, Ogawa M, Bengoechea R, Pittman SK, Hayashi S, Watanabe K, Hosoi Y, Sano T, Takao M, Oya Y, Takahashi Y, Miyajima H, Weihl CC, Inoue T, Nishino I
Acta neuropathologica 2023 Feb;145(2):235-255
Acta neuropathologica 2023 Feb;145(2):235-255
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Zhu D, Kong M, Chen C, Luo J, Kong L
International immunopharmacology 2023 Feb;115:109689
International immunopharmacology 2023 Feb;115:109689
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Liu XM, Li Z, Xie XR, Wang JQ, Qiao X, Qiao X, Xie CZ, Xu JY
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure.
Wang A, Guo Y, Ding S, Yu Y, Yuan Z, Zhang H, Liu Y
Frontiers in bioscience (Landmark edition) 2023 Feb 24;28(2):34
Frontiers in bioscience (Landmark edition) 2023 Feb 24;28(2):34
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Chen SJ, Huang Y, Yu F, Feng X, Zheng YY, Li Q, Niu Q, Jiang YH, Zhao LQ, Wang M, Cheng PP, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
Lu R, Wei Z, Wang Z, Xu S, Sun K, Cheng P, Huang X, You H, Guo F, Liang S, Chen AM
iScience 2023 Feb 17;26(2):105936
iScience 2023 Feb 17;26(2):105936
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Xu J, Wu D, Zhou S, Hu H, Li F, Guan Z, Zhan X, Gao Y, Wang P, Rao Z
Cell death discovery 2023 Feb 10;9(1):58
Cell death discovery 2023 Feb 10;9(1):58
Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKβ-AMPK-mTOR-mediated autophagy.
Ma S, Xu J, Zheng Y, Li Y, Wang Y, Li H, Fang Z, Li J
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115878
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115878
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
Sun X, Du J, Meng H, Liu F, Yang N, Deng S, Wan H, Ye D, Song E, Zeng H
Cell biology and toxicology 2023 Dec;39(6):3255-3267
Cell biology and toxicology 2023 Dec;39(6):3255-3267
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.
Zhou M, Boulos JC, Klauck SM, Efferth T
Cell biology and toxicology 2023 Dec;39(6):2971-2997
Cell biology and toxicology 2023 Dec;39(6):2971-2997
Ame-miR-980-3p participates in autophagy-mediated midgut remodelling in Apis mellifera via targeting Atg2B.
Chen WF, Chi XP, Song HY, Wang HF, Wang Y, Liu ZG, Xu BH
Insect molecular biology 2023 Dec;32(6):748-760
Insect molecular biology 2023 Dec;32(6):748-760
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway.
Xiong Y, Huang CW, Shi C, Peng L, Cheng YT, Hong W, Liao J
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2363-2380
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2363-2380
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103
Theriogenology 2023 Dec;212:91-103
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Lu D, Liu Y, Huang H, Hu M, Li T, Wang S, Shen S, Wu R, Cai W, Lu T, Lu Z
Translational stroke research 2023 Dec;14(6):910-928
Translational stroke research 2023 Dec;14(6):910-928
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Xue R, Fan XL, Yang Q, Yu C, Lu TY, Wan GM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
FUNDC1/PFKP-mediated mitophagy induced by KD025 ameliorates cartilage degeneration in osteoarthritis.
Fang G, Wen X, Jiang Z, Du X, Liu R, Zhang C, Huang G, Liao W, Zhang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Dec 6;31(12):3594-3612
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Dec 6;31(12):3594-3612
SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1.
Li Y, Bie J, Song C, Li Y, Zhang T, Li H, Zhao L, You F, Luo J
EMBO reports 2023 Dec 6;24(12):e57500
EMBO reports 2023 Dec 6;24(12):e57500
Imidacloprid Induces Lysosomal Dysfunction and Cell Death in Human Astrocytes and Fibroblasts-Environmental Implication of a Clinical Case Report.
Eriksson I, Ward LJ, Vainikka L, Sultana N, Leanderson P, Flodin U, Li W, Yuan XM
Cells 2023 Dec 5;12(24)
Cells 2023 Dec 5;12(24)
A20 ameliorates Aspergillus fumigatus keratitis by promoting autophagy and inhibiting NF-κB signaling.
Han F, Wang L, Shen L, Liu W, Li Y, Ma H, Wu X
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
International journal of biological macromolecules 2023 Dec 31;253(Pt 8):127640
Cataract-causing mutations S78F and S78P of γD-crystallin decrease protein conformational stability and drive aggregation.
Lin N, Zhang Y, Song X, Xu J, Luo C, Tian Q, Yao K, Wu W, Chen X, Hu L
International journal of biological macromolecules 2023 Dec 31;253(Pt 4):126910
International journal of biological macromolecules 2023 Dec 31;253(Pt 4):126910
Tetrahydropalmatine: Orchestrating survival - Regulating autophagy and apoptosis via the PI3K/AKT/mTOR pathway in perforator flaps.
Chen X, Fu K, Lai Y, Dong C, Chen Z, Huang Y, Li G, Jiang R, Wu H, Wang A, Huang S, Shen L, Gao W, Li S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115887
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115887
GNL3L promotes autophagy via regulating AMPK signaling in esophageal cancer cells.
He W, Sun F, Li W, Du R, Yan S, Liu C
Medical oncology (Northwood, London, England) 2023 Dec 26;41(1):29
Medical oncology (Northwood, London, England) 2023 Dec 26;41(1):29
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Data-independent acquisition (DIA) mass spectrometry reveals related proteins involved in the occurrence of early intestinal-type gastric cancer.
Zhang L, Xu F, Lu H, Dong X, Gao Z, Zhao Q, Weng T, Li H, Ye H
Medical oncology (Northwood, London, England) 2023 Dec 19;41(1):23
Medical oncology (Northwood, London, England) 2023 Dec 19;41(1):23
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Furthmann N, Bader V, Angersbach L, Blusch A, Goel S, Sánchez-Vicente A, Krause LJ, Chaban SA, Grover P, Trinkaus VA, van Well EM, Jaugstetter M, Tschulik K, Damgaard RB, Saft C, Ellrichmann G, Gold R, Koch A, Englert B, Westenberger A, Klein C, Jungbluth L, Sachse C, Behrends C, Glatzel M, Hartl FU, Nakamura K, Christine CW, Huang EJ, Tatzelt J, Winklhofer KF
Nature communications 2023 Dec 19;14(1):8368
Nature communications 2023 Dec 19;14(1):8368
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants.
Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Journal of the American Heart Association 2023 Dec 19;12(24):e029938
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects.
Tan S, Wang D, Fu Y, Zheng H, Liu Y, Lu B
Science bulletin 2023 Dec 15;68(23):3013-3026
Science bulletin 2023 Dec 15;68(23):3013-3026
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Liu J, Sun Y, Chen W, Deng L, Chen M, Dong J
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
Blockade of CXCR4 promotes macrophage autophagy through the PI3K/AKT/mTOR pathway to alleviate coronary heart disease.
Li F, Peng J, Lu Y, Zhou M, Liang J, Le C, Ding J, Wang J, Dai J, Wan C, Wang J, Luo P, Xia B
International journal of cardiology 2023 Dec 1;392:131303
International journal of cardiology 2023 Dec 1;392:131303
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
Wang Y, Li B, Liu G, Han Q, Diao Y, Liu J
Life sciences 2023 Dec 1;334:122176
Life sciences 2023 Dec 1;334:122176
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139
Tissue & cell 2023 Aug;83:102139
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Jiang X, Xu Y, Yang J, Wang J, Gao L, Yu L
Cell biology international 2023 Aug;47(8):1453-1465
Cell biology international 2023 Aug;47(8):1453-1465
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
He P, He Y, Ma J, Liu Y, Liu C, Baoping Y, Dong W
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Artemether ameliorates adriamycin induced cardiac atrophy in mice.
Weng W, Yu X, Dong Y, Wang T, Shao M, Sun H, Han P
Molecular medicine reports 2023 Aug;28(2)
Molecular medicine reports 2023 Aug;28(2)
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Zhou J, Lu Y, Lin Y, Li C, Liu J, Jiang Z, Chen K
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:1-15
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:1-15
Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.
Li Z, Yin X, Lyu C, Wang T, Wang W, Zhang J, Wang J, Wang Z, Han C, Zhang R, Guo D, Xu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114988
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114988
Arginine regulates HSPA5/BiP translation through ribosome pausing in triple-negative breast cancer cells.
Vidal CM, Ouyang C, Qi Y, Mendez-Dorantes C, Coblentz A, Alva-Ornelas JA, Stark JM, Seewaldt VL, Ann DK
British journal of cancer 2023 Aug;129(3):444-454
British journal of cancer 2023 Aug;129(3):444-454
Experimental Study of Warburg Effect in Keloid Nodules: Implication for Downregulation of miR-133b.
Lee Y, Ito Y, Taniguchi K, Nuri T, Lee S, Ueda K
Plastic and reconstructive surgery. Global open 2023 Aug;11(8):e5202
Plastic and reconstructive surgery. Global open 2023 Aug;11(8):e5202
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
Li T, Su X, Lu P, Kang X, Hu M, Li C, Wang S, Lu D, Shen S, Huang H, Liu Y, Deng X, Cai W, Wei L, Lu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
The Chicken cGAS-STING Pathway Exerts Interferon-Independent Antiviral Function via Cell Apoptosis.
Jiang S, Lv M, Zhang D, Cao Q, Xia N, Luo J, Zheng W, Chen N, Meurens F, Zhu J
Animals : an open access journal from MDPI 2023 Aug 9;13(16)
Animals : an open access journal from MDPI 2023 Aug 9;13(16)
TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines.
Zhang Q, Dan J, Meng S, Li Y, Li J
Gene 2023 Aug 5;876:147520
Gene 2023 Aug 5;876:147520
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Yu X, Liu X, Mi X, Luo X, Lian Z, Tang J, Wang G
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Liu Y, Chen X, Zhao Y, Wang XY, Luo YW, Chen L, Wang W, Zhong S, Hu M, Dai Z, Jiang J, Wang X, Ji H, Cheng XX, Zheng A, Zuo J, Liu H, Ma D, Luo Z, Cao F, Hu S, Huang AL, Tang KF
Cell reports 2023 Aug 29;42(8):112852
Cell reports 2023 Aug 29;42(8):112852
Metabolomic Analysis of Trehalose Alleviating Oxidative Stress in Myoblasts.
Zhang S, Qiu X, Zhang Y, Huang C, Lin D
International journal of molecular sciences 2023 Aug 28;24(17)
International journal of molecular sciences 2023 Aug 28;24(17)
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
Shi M, Zhang J, Li M, Zhao Y, Guo Y, Xu J, Liu R, Li Z, Ren D, Liu P
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
Xu C, Pan X, Wang D, Guan Y, Yang W, Chen X, Liu Y
Molecular cell 2023 Aug 17;83(16):3027-3040.e11
Molecular cell 2023 Aug 17;83(16):3027-3040.e11
In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia.
Boulos JC, Chatterjee M, Shan L, Efferth T
Cancers 2023 Aug 16;15(16)
Cancers 2023 Aug 16;15(16)
Adipose-derived mesenchymal stem cell therapy for reverse bleomycin-induced experimental pulmonary fibrosis.
Zhao X, Wu J, Yuan R, Li Y, Yang Q, Wu B, Zhai X, Wang J, Magalon J, Sabatier F, Daumas A, Zhu WM, Zhu N
Scientific reports 2023 Aug 14;13(1):13183
Scientific reports 2023 Aug 14;13(1):13183
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics.
Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, Shan Z, Peng X
Nutrients 2023 Aug 11;15(16)
Nutrients 2023 Aug 11;15(16)
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Li D, Dun Y, Qi D, Ripley-Gonzalez JW, Dong J, Zhou N, Qiu L, Zhang J, Zeng T, You B, Liu S
Scientific reports 2023 Aug 11;13(1):13068
Scientific reports 2023 Aug 11;13(1):13068
Dysregulation of lipid metabolism in the pseudolobule promotes region-specific autophagy in hepatitis B liver cirrhosis.
Pu W, Wang X, Zhong X, Zhao D, Zeng Z, Cai W, Zhong Y, Huang J, Tang D, Dai Y
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Liu M, Yu Z, Yang F, Zhao Z, Zhou M, Wang C, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Aug 1;494:153581
Toxicology 2023 Aug 1;494:153581
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
Wang X, Song M, Li X, Su C, Yang Y, Wang K, Liu C, Zheng Z, Jia Y, Ren S, Dong W, Chen J, Wang T, Liu L, Guan M, Zhang C, Xue Y
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y
Cell death & disease 2023 Aug 1;14(8):488
Cell death & disease 2023 Aug 1;14(8):488
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Zhu LL, Shi JJ, Guo YD, Yang C, Wang RL, Li SS, Gan DX, Ma PX, Li JQ, Su HC
Neoplasma 2023 Apr;70(2):272-286
Neoplasma 2023 Apr;70(2):272-286
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway.
Song CF, Hu YH, Mang ZG, Ye Z, Chen HD, Jing DS, Fan GX, Ji SR, Yu XJ, Xu XW, Qin Y
Acta pharmacologica Sinica 2023 Apr;44(4):865-876
Acta pharmacologica Sinica 2023 Apr;44(4):865-876
Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells.
Li J, Wang SH, Liu YT, Zhang Q, Zhou GZ
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23307
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23307
Mitochondria-associated endoplasmic reticulum membranes dysfunction contributes to PARP-1-dependent cell death under oxidative stress in retinal precursor cells.
Yang Y, Wu J, Lu W, Dai Y, Zhang Y, Sun X
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23303
Journal of biochemical and molecular toxicology 2023 Apr;37(4):e23303
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
Li X, Li Y, Liu B, Chen L, Lyu F, Zhang P, He Q, Cheng L, Liu C, Song Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance.
Wang C, Li X, Zhang W, Liu W, Lv Z, Gui R, Li M, Li Y, Sun X, Liu P, Fan X, Yang S, Xiong Y, Qian L
Free radical biology & medicine 2023 Apr;199:126-140
Free radical biology & medicine 2023 Apr;199:126-140
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hao J, Li J, Zhang Z, Yang Y, Zhou Q, Wu T, Chen T, Wu Z, Zhang P, Cui J, Li YP
Autophagy 2023 Apr;19(4):1332-1347
Autophagy 2023 Apr;19(4):1332-1347
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway.
Jin D, Zhao Y, Sun Y, Xue J, Li X, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114340
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114340
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
Zhou F, Li X, Xue X, Li S, Fan G, Cai Y, Chang Z, Qu J, Liu R
Advanced healthcare materials 2023 Apr;12(11):e2202757
Advanced healthcare materials 2023 Apr;12(11):e2202757
ATG2B upregulated in LPS-stimulated BMSCs-derived exosomes attenuates septic liver injury by inhibiting macrophage STING signaling.
Liu J, Tang M, Li Q, Li Q, Dai Y, Zhou H
International immunopharmacology 2023 Apr;117:109931
International immunopharmacology 2023 Apr;117:109931
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Tan H, Cao L
Immunity, inflammation and disease 2023 Apr;11(4):e830
Immunity, inflammation and disease 2023 Apr;11(4):e830
Pathogenic mechanism of Eimeria tenella autophagy activation of chicken embryo cecal epithelial cells induced by Eimeria tenella.
Zhang Y, Duan BT, Zhao YJ, Cui KL, Xu T, Zhang XS, Lv XL, Guo LL, Zheng MX, Bai R
Poultry science 2023 Apr;102(4):102535
Poultry science 2023 Apr;102(4):102535
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux.
Saha K, Subramenium Ganapathy A, Wang A, Michael Morris N, Suchanec E, Ding W, Yochum G, Koltun W, Nighot M, Ma T, Nighot P
Journal of Crohn's & colitis 2023 Apr 3;17(3):433-449
Journal of Crohn's & colitis 2023 Apr 3;17(3):433-449
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Wang W, Liu Y, Xiong L, Sun D, Wang H, Song Z, Li Y, Li H, Chen L
Journal of natural products 2023 Apr 28;86(4):767-781
Journal of natural products 2023 Apr 28;86(4):767-781
Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.
Zhu X, Guan Z, Fang Y, Zhang Y, Guan Z, Li S, Peng K
Journal of virology 2023 Apr 27;97(4):e0181422
Journal of virology 2023 Apr 27;97(4):e0181422
The SFTSV Nonstructural Proteins Induce Autophagy to Promote Viral Replication via Interaction with Vimentin.
Liu S, Su Y, Lu Z, Zou X, Xu L, Teng Y, Wang Z, Wang T
Journal of virology 2023 Apr 27;97(4):e0030223
Journal of virology 2023 Apr 27;97(4):e0030223
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Wang G, Qin S, Chen L, Geng H, Zheng Y, Xia C, Yao J, Deng L
Cell death & disease 2023 Apr 25;14(4):292
Cell death & disease 2023 Apr 25;14(4):292
MicroRNA-196-5p targets Derlin-1 to induce autophagy in human osteosarcoma cells.
Ji Z, Chen W, Wan S, Zhang Y, Xu J
Acta biochimica Polonica 2023 Apr 23;70(2):313-323
Acta biochimica Polonica 2023 Apr 23;70(2):313-323
STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy.
Wan W, Qian C, Wang Q, Li J, Zhang H, Wang L, Pu M, Huang Y, He Z, Zhou T, Shen HM, Liu W
The EMBO journal 2023 Apr 17;42(8):e112387
The EMBO journal 2023 Apr 17;42(8):e112387
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells.
Xie Y, Fan S, Ni D, Wan W, Xu P, Ding Y, Zhang R, Lu J, Zhang N, Zhang Y, Xiao W, Zhao K, Luo C
Bioorganic & medicinal chemistry 2023 Apr 15;84:117262
Bioorganic & medicinal chemistry 2023 Apr 15;84:117262
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Tang Y, Zhang J, Hu Z, Xu W, Xu P, Ma Y, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)
Biology 2023 Apr 11;12(4)
Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.
Liu X, Tan S, Liu H, Jiang J, Wang X, Li L, Wu B
Hepatology (Baltimore, Md.) 2023 Apr 1;77(4):1181-1197
Hepatology (Baltimore, Md.) 2023 Apr 1;77(4):1181-1197
SUMO1 Promotes Mesangial Cell Proliferation Through Inhibiting Autophagy in a Cell Model of IgA Nephropathy.
Tan X, Liu Y, Liu D, Tang X, Xia M, Chen G, He L, Zhu X, Liu H
Frontiers in medicine 2022;9:834164
Frontiers in medicine 2022;9:834164
The KLF4-p62 axis prevents vascular endothelial cell injury via the mTOR/S6K pathway and autophagy in diabetic kidney disease.
Wang X, Su W, Ma M, Zhu L, Gao R, Qin C, Shao S, Gao D, Gao J, Zhang Z
Endokrynologia Polska 2022;73(5):837-845
Endokrynologia Polska 2022;73(5):837-845
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334
Folia histochemica et cytobiologica 2022;60(4):323-334
BRD4 Inhibition Suppresses Senescence and Apoptosis of Nucleus Pulposus Cells by Inducing Autophagy during Intervertebral Disc Degeneration: An In Vitro and In Vivo Study.
Zhang GZ, Chen HW, Deng YJ, Liu MQ, Wu ZL, Ma ZJ, He XG, Gao YC, Kang XW
Oxidative medicine and cellular longevity 2022;2022:9181412
Oxidative medicine and cellular longevity 2022;2022:9181412
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S, Liu H, Wang B
Oxidative medicine and cellular longevity 2022;2022:8287227
Oxidative medicine and cellular longevity 2022;2022:8287227
Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells.
Zhou H, Pan P, Zhao Q, Liu W, Sun Y, Wang J, Liu C, Wang C
BioMed research international 2022;2022:6022981
BioMed research international 2022;2022:6022981
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Zhu X, Tao F, Zhang L, Yu Y, Xu Y, Yang G, Wei Z, Cheng Y, Yin X, Zhang X, Wei W, Wang A
Oxidative medicine and cellular longevity 2022;2022:5757367
Oxidative medicine and cellular longevity 2022;2022:5757367
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
SIRT2 Affects Cell Proliferation and Apoptosis by Suppressing the Level of Autophagy in Renal Podocytes.
Liu S, Gao X, Fan Z, Wang Q
Disease markers 2022;2022:4586198
Disease markers 2022;2022:4586198
Discovery of Therapeutic Candidates for Diabetic Retinopathy Based on Molecular Switch Analysis: Application of a Systematic Process.
Ren Y, Liu Y, Liu K, Huo X, Liu C, Zhang Y
Oxidative medicine and cellular longevity 2022;2022:3412032
Oxidative medicine and cellular longevity 2022;2022:3412032
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Hu Z, Wen T, Hu K, Wang R, Su X, Ouyang W, Zhou J, Wen Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Li H, Wang Y, Su X, Wang Q, Zhang S, Sun W, Zhang T, Dong M, Zhang Z, Lv S
Journal of diabetes research 2022;2022:2640209
Journal of diabetes research 2022;2022:2640209
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Chen P, Yang J, Wu N, Han B, Kastelic JP, Gao J
Oxidative medicine and cellular longevity 2022;2022:2549772
Oxidative medicine and cellular longevity 2022;2022:2549772
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux.
Zhang QQ, Luo L, Liu MX, Wang CJ, Wu Y, Yu KW
Mediators of inflammation 2022;2022:2396487
Mediators of inflammation 2022;2022:2396487
Mesangial Cell-Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2.
Yu M, Shen X, He W, Zheng D, He Q, Jin J
Oxidative medicine and cellular longevity 2022;2022:1740770
Oxidative medicine and cellular longevity 2022;2022:1740770
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
Zhou D, Yao Y, Zong L, Zhou G, Feng M, Chen J, Liu G, Chen G, Sun K, Yao H, Liu Y, Shi X, Zhang W, Shi B, Tai Q, Wu G, Sun L, Hu W, Zhu X, He S
International journal of biological sciences 2022;18(8):3374-3389
International journal of biological sciences 2022;18(8):3374-3389
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin YH, Smith EF, Illanes-Álvarez F, Higginbottom A, Shaw PJ, Azzouz M, Ferraiuolo L, Hautbergue GM, Grierson AJ, De Vos KJ
Frontiers in cellular neuroscience 2022;16:1061559
Frontiers in cellular neuroscience 2022;16:1061559
Shikonin Attenuates Cochlear Spiral Ganglion Neuron Degeneration by Activating Nrf2-ARE Signaling Pathway.
Du H, Zhou X, Shi L, Xia M, Wang Y, Guo N, Hu H, Zhang P, Yang H, Zhu F, Teng Z, Liu C, Zhao M
Frontiers in molecular neuroscience 2022;15:829642
Frontiers in molecular neuroscience 2022;15:829642
Beclin1 Deficiency Suppresses Epileptic Seizures.
Yang M, Lin P, Jing W, Guo H, Chen H, Chen Y, Guo Y, Gu Y, He M, Wu J, Jiang X, Zou Z, Xu X, Chen C, Xiao F, Wang X, Tian X
Frontiers in molecular neuroscience 2022;15:807671
Frontiers in molecular neuroscience 2022;15:807671
The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.
Mao XT, Zou WB, Cao Y, Wang YC, Deng SJ, Cooper DN, Férec C, Li ZS, Chen JM, Liao Z
Cellular and molecular gastroenterology and hepatology 2022;14(1):55-74
Cellular and molecular gastroenterology and hepatology 2022;14(1):55-74
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Xu M, Liu Y, Mayinuer T, Lin Y, Wang Y, Gao J, Wang D, Kastelic JP, Han B
Frontiers in microbiology 2022;13:935547
Frontiers in microbiology 2022;13:935547
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
Zhao W, Xu M, Barkema HW, Xie X, Lin Y, Khan S, Kastelic JP, Wang D, Deng Z, Han B
Frontiers in immunology 2022;13:934819
Frontiers in immunology 2022;13:934819
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Li L, Chen X, Lv M, Cheng Z, Liu F, Wang Y, Zhou A, Liu J, Zhao X
Frontiers in immunology 2022;13:934084
Frontiers in immunology 2022;13:934084
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
Hu H, Li P, Qiu J, Zhao M, Kuang M, Zhang Z, Wang D
Frontiers in pharmacology 2022;13:932807
Frontiers in pharmacology 2022;13:932807
EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway.
Wang L, Dai M, Ge Y, Chen J, Wang C, Yao C, Lin Y
Frontiers in pharmacology 2022;13:921394
Frontiers in pharmacology 2022;13:921394
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
You X, Wu Y, Li Q, Sheng W, Zhou Q, Fu W
Frontiers in pharmacology 2022;13:895696
Frontiers in pharmacology 2022;13:895696
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Hu Z, Wang Y, Gao X, Zhang Y, Liu C, Zhai Y, Chang X, Li H, Li Y, Lou J, Li C
Frontiers in pharmacology 2022;13:893307
Frontiers in pharmacology 2022;13:893307
Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection.
Wu Y, Zhou T, Hu J, Liu Y, Jin S, Wu J, Guan X, Cui J
Frontiers in microbiology 2022;13:889693
Frontiers in microbiology 2022;13:889693
Liuwei Dihuang Pills Inhibit Podocyte Injury and Alleviate IgA Nephropathy by Directly Altering Mesangial Cell-Derived Exosome Function and Secretion.
Zhu X, Shen X, Lin B, Fang J, Jin J, He Q
Frontiers in pharmacology 2022;13:889008
Frontiers in pharmacology 2022;13:889008
Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy.
Yi X, Yan W, Guo T, Liu N, Wang Z, Shang J, Wei X, Cui X, Sun Y, Ren S, Chen L
Frontiers in pharmacology 2022;13:883057
Frontiers in pharmacology 2022;13:883057
Intracellular Ca(2+) Signaling and Calcium Release-Activated Calcium Modulator ORAI1 Are Associated With CD4(+) T Lymphocytes in Dairy Cows.
Li M, Zhang B, Yin Y, Wen J, Wang J, He Y, Jiang Q, Loor JJ, Wang S, Yang W, Xu C
Frontiers in immunology 2022;13:835936
Frontiers in immunology 2022;13:835936
Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.
Tong F, Xu L, Xu S, Zhang M
Frontiers in genetics 2022;13:834935
Frontiers in genetics 2022;13:834935
Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control.
Yan M, Jin S, Liu Y, Wang L, Wang Z, Xia T, Chang Q
Frontiers in pharmacology 2022;13:824138
Frontiers in pharmacology 2022;13:824138
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Zhao X, Jiang Y, Ren J, Wang Y, Zhao Y, Feng X
Frontiers in pharmacology 2022;13:794938
Frontiers in pharmacology 2022;13:794938
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Lu R, He Z, Zhang W, Wang Y, Cheng P, Lv Z, Yuan X, Guo F, You H, Chen AM, Hu W
Frontiers in endocrinology 2022;13:1060721
Frontiers in endocrinology 2022;13:1060721
Hydrogen sulfide alleviates uremic cardiomyopathy by regulating PI3K/PKB/mTOR-mediated overactive autophagy in 5/6 nephrectomy mice.
Feng J, Li H, Wang S
Frontiers in pharmacology 2022;13:1027597
Frontiers in pharmacology 2022;13:1027597
Characterization and subcellular localization of Alongshan virus proteins.
Zhao Y, Wu P, Liu L, Ma B, Pan M, Huang Y, Du N, Yu H, Sui L, Wang ZD, Hou Z, Liu Q
Frontiers in microbiology 2022;13:1000322
Frontiers in microbiology 2022;13:1000322
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Zheng W, Wang K, Wu Y, Yan G, Zhang C, Li Z, Wang L, Chen S
Theranostics 2022;12(17):7289-7306
Theranostics 2022;12(17):7289-7306
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Zhu Z, Wang X, Zhang W, Gong M, Zhang S, Yang B, Qu B, Wu Z, Ma Q, Wang Z, Qian W
Frontiers in oncology 2022;12:960858
Frontiers in oncology 2022;12:960858
Autophagy-Related Signatures as Prognostic Indicators for Hepatocellular Carcinoma.
Ye W, Shi Z, Zhou Y, Zhang Z, Zhou Y, Chen B, Zhang Q
Frontiers in oncology 2022;12:654449
Frontiers in oncology 2022;12:654449
PIN1 protects auditory hair cells from senescence via autophagy.
Lv Z, Zhang Y, Cao H, Liu Q, Feng X, Yin H, Wang B
PeerJ 2022;10:e14267
PeerJ 2022;10:e14267
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Peng X, Yang R, Peng W, Zhao Z, Tu G, He B, Cai Q, Shi S, Yin W, Yu F, Tao Y, Wang X
PeerJ 2022;10:e14180
PeerJ 2022;10:e14180
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
Ma X, Gao HJ, Zhang Q, Yang MG, Bi ZJ, Ji SQ, Li Y, Xu L, Bu BT
Frontiers in cell and developmental biology 2022;10:791986
Frontiers in cell and developmental biology 2022;10:791986
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Lu J, Li R, Ni S, Xie Y, Liu X, Zhang K, Li Y
Frontiers in bioengineering and biotechnology 2022;10:1002291
Frontiers in bioengineering and biotechnology 2022;10:1002291
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
Wu J, Zhou F, Fan G, Liu J, Wang Y, Xue X, Lyu X, Lin S, Li X
IUBMB life 2022 Sep;74(9):880-895
IUBMB life 2022 Sep;74(9):880-895
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway.
Zhao L, Lan Z, Peng L, Wan L, Liu D, Tan X, Tang C, Chen G, Liu H
Cell proliferation 2022 Sep;55(9):e13278
Cell proliferation 2022 Sep;55(9):e13278
Gold nanoparticles targeting the autophagy-lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy.
Yin Y, Tian BM, Li X, Yu YC, Deng DK, Sun LJ, Qu HL, Wu RX, Xu XY, Sun HH, An Y, He XT, Chen FM
Biomaterials 2022 Sep;288:121743
Biomaterials 2022 Sep;288:121743
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis.
Zhang S, Xie Y, Yan F, Zhang Y, Yang Z, Chen Z, Zhao Y, Huang Z, Cai L, Deng Z
Autophagy 2022 Sep;18(9):2229-2245
Autophagy 2022 Sep;18(9):2229-2245
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.
Ganapathy AS, Saha K, Suchanec E, Singh V, Verma A, Yochum G, Koltun W, Nighot M, Ma T, Nighot P
Autophagy 2022 Sep;18(9):2086-2103
Autophagy 2022 Sep;18(9):2086-2103
Ferulic acid ameliorates renal injury via improving autophagy to inhibit inflammation in diabetic nephropathy mice.
Ma R, He Y, Fang Q, Xie G, Qi M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113424
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113424
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Zhu M, Zhang Y, Pan J, Tong X, Zhang X, Hu X, Gong C
Fish & shellfish immunology 2022 Sep;128:148-156
Fish & shellfish immunology 2022 Sep;128:148-156
Sodium butyrate attenuates bovine mammary epithelial cell injury by inhibiting the formation of neutrophil extracellular traps.
Li Y, Liu J, Cui Y, Cao Y, Xu P, Kan X, Guo W, Fu S
International immunopharmacology 2022 Sep;110:109009
International immunopharmacology 2022 Sep;110:109009
Selenomethionine alleviates NF-κB-mediated inflammation in bovine mammary epithelial cells induced by Escherichia coli by enhancing autophagy.
Tao L, Liu K, Li J, Zhang Y, Cui L, Dong J, Meng X, Zhu G, Wang H
International immunopharmacology 2022 Sep;110:108989
International immunopharmacology 2022 Sep;110:108989
Lactobacillusjohnsonii L531 Protects against Salmonella Infantis-Induced Intestinal Damage by Regulating the NOD Activation, Endoplasmic Reticulum Stress, and Autophagy.
Yang L, Wang JF, Liu N, Wang X, Wang J, Yang GH, Yang GY, Zhu YH
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, Wu Y, Sun L, Li C, Xie W, Zhao Y, Songyang Z, Peng K, Zhao J, Cui J
Nature communications 2022 Sep 3;13(1):5204
Nature communications 2022 Sep 3;13(1):5204
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation.
Chen Y, Qian J, Ding P, Wang W, Li X, Tang X, Tang C, Yang Y, Gu C
Cell death & disease 2022 Sep 26;13(9):822
Cell death & disease 2022 Sep 26;13(9):822
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351
Nature communications 2022 Sep 12;13(1):5351
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Wang H, Liang Z, Gou Y, Li Z, Cao Y, Jiao N, Tan J, Yu Y, Zhang Z
Cellular signalling 2022 Oct;98:110406
Cellular signalling 2022 Oct;98:110406
Puerarin prevents calcium oxalate crystal-induced renal epithelial cell autophagy by activating the SIRT1-mediated signaling pathway.
Jing GH, Liu YD, Liu JN, Jin YS, Yu SL, An RH
Urolithiasis 2022 Oct;50(5):545-556
Urolithiasis 2022 Oct;50(5):545-556
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity.
Xie W, Tian S, Yang J, Cai S, Jin S, Zhou T, Wu Y, Chen Z, Ji Y, Cui J
Autophagy 2022 Oct;18(10):2288-2302
Autophagy 2022 Oct;18(10):2288-2302
Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway.
Lin SR, Lin QM, Lin YJ, Qian X, Wang XP, Gong Z, Chen F, Song B
Neural regeneration research 2022 Oct;17(10):2232-2237
Neural regeneration research 2022 Oct;17(10):2232-2237
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Song W, Zeng Z, Zhang Y, Li H, Cheng H, Wang J, Wu F
Cell death & disease 2022 Oct 8;13(10):857
Cell death & disease 2022 Oct 8;13(10):857
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924
Nature communications 2022 Oct 7;13(1):5924
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Tang X, Liang Y, Sun G, He Q, Hou Z, Jiang X, Gao P, Qu H
Cell death & disease 2022 Oct 4;13(10):848
Cell death & disease 2022 Oct 4;13(10):848
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Combination of an autophagy inhibitor with immunoadjuvants and an anti-PD-L1 antibody in multifunctional nanoparticles for enhanced breast cancer immunotherapy.
Cheng Y, Wang C, Wang H, Zhang Z, Yang X, Dong Y, Ma L, Luo J
BMC medicine 2022 Oct 28;20(1):411
BMC medicine 2022 Oct 28;20(1):411
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
DDX17 promotes the growth and metastasis of lung adenocarcinoma.
Liu X, Li L, Geng C, Wen S, Zhang C, Deng C, Gao X, Zhang G, He QY, Liu L
Cell death discovery 2022 Oct 22;8(1):425
Cell death discovery 2022 Oct 22;8(1):425
Down-regulation of EVA1A by miR-103a-3p promotes hepatocellular carcinoma cells proliferation and migration.
Xu Q, Liao Z, Gong Z, Liu X, Yang Y, Wang Z, Yang W, Hou L, Yang J, Song J, Liu W, Wang B, Hua J, Pu M, Li N
Cellular & molecular biology letters 2022 Oct 22;27(1):93
Cellular & molecular biology letters 2022 Oct 22;27(1):93
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
Lv Z, Qiu X, Jin P, Li Z, Zhang Y, Lv L, Song F
Life (Basel, Switzerland) 2022 Oct 20;12(10)
Life (Basel, Switzerland) 2022 Oct 20;12(10)
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
Fan H, Cui J, Liu F, Zhang W, Yang H, He N, Dong Z, Dong J
European journal of pharmacology 2022 Oct 15;933:175252
European journal of pharmacology 2022 Oct 15;933:175252
Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus.
Baytas O, Kauer JA, Morrow EM
Neurobiology of disease 2022 Oct 15;173:105831
Neurobiology of disease 2022 Oct 15;173:105831
Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue.
Li Y, Hao D, Wei D, Xiao Y, Liu L, Li X, Wang L, Gan Y, Yan W, Ke B, Jiang X
Molecules (Basel, Switzerland) 2022 Oct 10;27(19)
Molecules (Basel, Switzerland) 2022 Oct 10;27(19)
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.
Cai Y, Zhu Y, Zheng J, Zhang Y, Chen W
Biochemical and biophysical research communications 2022 Oct 1;623:140-147
Biochemical and biophysical research communications 2022 Oct 1;623:140-147
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Zheng H, Liu Q, Wang S, Liu X, Ma M, Shen T, Wang X, Ren D
Chemico-biological interactions 2022 Oct 1;366:110125
Chemico-biological interactions 2022 Oct 1;366:110125
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Wen F, Zhan Q, Zou T, Tan ZG, Xiang J
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
Subsarcolemmal and cytoplasmic p62 positivity and rimmed vacuoles are distinctive for PLIN4-myopathy.
Wang Q, Yu M, Zhang W, Gang Q, Xie Z, Xu J, Zhou C, Wang D, Meng L, Lv H, Jia Z, Deng J, Yuan Y, Wang Z
Annals of clinical and translational neurology 2022 Nov;9(11):1813-1819
Annals of clinical and translational neurology 2022 Nov;9(11):1813-1819
Palmatine attenuates hepatocyte injury by promoting autophagy via the AMPK/mTOR pathway after alcoholic liver disease.
Lin GS, Zhao MM, Fu QC, Zhao SY, Ba TT, Yu HX
Drug development research 2022 Nov;83(7):1613-1622
Drug development research 2022 Nov;83(7):1613-1622
Impaired autophagy and mitochondrial dynamics are involved in Sorafenib-induced cardiomyocyte apoptosis.
Liang F, Zhang K, Ma W, Zhan H, Sun Q, Xie L, Zhao Z
Toxicology 2022 Nov;481:153348
Toxicology 2022 Nov;481:153348
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Tai S, Sun J, Zhou Y, Zhu Z, He Y, Chen M, Yang H, Xiao Y, Tu T, Tang L, Li X, Zeng J, Zheng X, Zhou S
Journal of advanced research 2022 Nov;41:205-218
Journal of advanced research 2022 Nov;41:205-218
Curcumin attenuates Cr (VI)-induced cell growth and migration by targeting autophagy-dependent reprogrammed metabolism.
Dlamini MB, Bao S, Gao Z, Mei J, Ge H, Jiang L, Geng C, Li Q, Shi X, Liu Y, Cao J
Journal of biochemical and molecular toxicology 2022 Nov;36(11):e23193
Journal of biochemical and molecular toxicology 2022 Nov;36(11):e23193
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Li H, Xu J, Zhang Y, Hong L, He Z, Zeng Z, Zhang L
Human cell 2022 Nov;35(6):1684-1696
Human cell 2022 Nov;35(6):1684-1696
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Wang J, Yang G, Zhang L, Zhang J, Wang J, Zou Y, Wang J
Virus research 2022 Nov;321:198905
Virus research 2022 Nov;321:198905
Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity.
Xiao Y, Wang J, Wang J, Wang H, Wu S, Bao W
Ecotoxicology and environmental safety 2022 Nov;246:114183
Ecotoxicology and environmental safety 2022 Nov;246:114183
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Shang Y, Sun X, Chen X, Wang Q, Wang EJ, Miller E, Xu R, Pieper AA, Qi X
Acta neuropathologica 2022 Nov;144(5):911-938
Acta neuropathologica 2022 Nov;144(5):911-938
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Wang Y, Zhu M, Liang J, Zhang N, Sun D, Li H, Chen L
Bioorganic chemistry 2022 Nov;128:106067
Bioorganic chemistry 2022 Nov;128:106067
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Zhou X, Li X, Yi K, Liang C, Geng S, Zhu J, Xie C, Zhong C
Bioorganic chemistry 2022 Nov;128:106034
Bioorganic chemistry 2022 Nov;128:106034
Paeoniflorin binds to VEGFR2 to restore autophagy and inhibit apoptosis for podocyte protection in diabetic kidney disease through PI3K-AKT signaling pathway.
Wang X, Jiang L, Liu XQ, Huang YB, Wang AL, Zeng HX, Gao L, Zhu QJ, Xia LL, Wu YG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154400
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154400
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Chen YH, Xu NZ, Hong C, Li WQ, Zhang YQ, Yu XY, Huang YL, Zhou JY
Cell death & disease 2022 Nov 8;13(11):939
Cell death & disease 2022 Nov 8;13(11):939
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D
Nature communications 2022 Nov 7;13(1):6704
Nature communications 2022 Nov 7;13(1):6704
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Ding Y, Xu Y, Fu Y, Zhang H, Zhao L, Fan X
Discover oncology 2022 Nov 6;13(1):121
Discover oncology 2022 Nov 6;13(1):121
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928
Cell death & disease 2022 Nov 5;13(11):928
The Clinicopathological Distinction between Immune-Mediated Necrotizing Myopathy and Limb-Girdle Muscular Dystrophy R2: Key Points to Prevent Misdiagnosis.
Yang M, Ji S, Xu L, Zhang Q, Li Y, Gao H, Bu B
Journal of clinical medicine 2022 Nov 5;11(21)
Journal of clinical medicine 2022 Nov 5;11(21)
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Yan X, Shang X, Feng Z, Chen B, Wu Y, Zhou Y, Li Y, Zhang L
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel.
Gabusi E, Lenzi E, Manferdini C, Dolzani P, Columbaro M, Saleh Y, Lisignoli G
Gels (Basel, Switzerland) 2022 Nov 24;8(12)
Gels (Basel, Switzerland) 2022 Nov 24;8(12)
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Qin S, Geng H, Wang G, Chen L, Xia C, Yao J, Bai Z, Deng L
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias.
Chen Y, Krishnan G, Parsi S, Pons M, Nikolaki V, Cao L, Xu Z, Gao FB
Acta neuropathologica communications 2022 Nov 22;10(1):169
Acta neuropathologica communications 2022 Nov 22;10(1):169
EGFR mediated the renal cell apoptosis in rhabdomyolysis-induced model via upregulation of autophagy.
Sun T, Wu D, Deng Y, Zhang D
Life sciences 2022 Nov 15;309:121050
Life sciences 2022 Nov 15;309:121050
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
Wang C, Li Z, Xu P, Xu L, Han S, Sun Y
Journal of nanobiotechnology 2022 Nov 11;20(1):476
Journal of nanobiotechnology 2022 Nov 11;20(1):476
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Li X, Zhu M, Zhao G, Zhou A, Min L, Liu S, Zhang N, Zhu S, Guo Q, Zhang S, Li P
Cellular signalling 2022 May;93:110286
Cellular signalling 2022 May;93:110286
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Lu X, Zhang J, Xue P, Wang Q, Wang X, Sun Y, Cui Z
Journal of physiology and biochemistry 2022 May;78(2):427-437
Journal of physiology and biochemistry 2022 May;78(2):427-437
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
Meng N, Dong Y, Huo T, Song M, Jiang X, Xiao Y, Lv P
Cellular and molecular neurobiology 2022 May;42(4):1021-1034
Cellular and molecular neurobiology 2022 May;42(4):1021-1034
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2022 May;200(5):2329-2337
Biological trace element research 2022 May;200(5):2329-2337
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models.
Mahmoud N, Hegazy MF, Wadie W, Elbadawi M, Fleischer E, Klinger A, Bringmann G, Khayyal MT, Efferth T
Pharmacological research 2022 May;179:106233
Pharmacological research 2022 May;179:106233
Ghrelin ameliorates diabetes-associated behavioral deficits and NLRP3 inflammasome activation via autophagic flux enhancement.
Han W, Cui C, Zhang H, Guo Y, Xie D, Zhang W, Wang C, Yang M, Jiang P
Pharmacological research 2022 May;179:106224
Pharmacological research 2022 May;179:106224
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Zhang D, Zheng N, Fu X, Shi J, Zhang J
Journal of thoracic disease 2022 May;14(5):1651-1662
Journal of thoracic disease 2022 May;14(5):1651-1662
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
Liu Y, Xiang H, Xiong W, Ouyang J, Liu H, Zhao S, Xiao J, Li J, Shu Z, Wang X, Liu H, Zhang J, Fan J, Li Y, Chen S, Lu H
Diabetes & vascular disease research 2022 May-Jun;19(3):14791641221102513
Diabetes & vascular disease research 2022 May-Jun;19(3):14791641221102513
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Hou Y, Wang S, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Yang G
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Meng Z, Zhu B, Gao M, Wang G, Zhou H, Lu J, Guan S
Food & function 2022 May 23;13(10):5559-5570
Food & function 2022 May 23;13(10):5559-5570
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
Yang J, Li J, Guo H, Zhang Y, Guo Z, Liu Y, Huo T
International journal of molecular sciences 2022 May 19;23(10)
International journal of molecular sciences 2022 May 19;23(10)
A transcriptomics and molecular biology based investigation reveals the protective effect and mechanism of carnosol on t-BHP induced HRMECs via Nrf2 signaling pathway.
Ren Y, Liu Y, Liu K, Shu Z, Lv T, Chen Z, Feng W, Zhang Y
European journal of pharmacology 2022 May 15;923:174933
European journal of pharmacology 2022 May 15;923:174933
SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism.
Zhang Y, Li T, Pan M, Wang W, Huang W, Yuan Y, Xie Z, Chen Y, Peng J, Li X, Meng Y
Journal of translational medicine 2022 May 14;20(1):222
Journal of translational medicine 2022 May 14;20(1):222
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Xia Y, Prokop S, Bell BM, Gorion KM, Croft CL, Nasif L, Xu G, Riffe CJ, Manaois AN, Strang KH, Quintin SS, Paterno G, Tansey MG, Borchelt DR, Golde TE, Giasson BI
Communications biology 2022 May 12;5(1):446
Communications biology 2022 May 12;5(1):446
Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation.
Yang S, Du Y, Zhao X, Tang Q, Su W, Hu Y, Yu P
International journal of molecular sciences 2022 May 11;23(10)
International journal of molecular sciences 2022 May 11;23(10)
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen L, Hu H, Wang L
Molecular and cellular endocrinology 2022 May 1;547:111598
Molecular and cellular endocrinology 2022 May 1;547:111598
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q
Ecotoxicology and environmental safety 2022 May 1;236:113500
Ecotoxicology and environmental safety 2022 May 1;236:113500
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
Zhang X, Jia Y, Yuan Z, Wen Y, Zhang Y, Ren J, Ji P, Yao W, Hua Y, Wei Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.
Zhao D, Zheng S, Wang X, Liu H, Zhao K, Li L, Hu Y
Oncogene 2022 Mar;41(13):1944-1958
Oncogene 2022 Mar;41(13):1944-1958
Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer's disease.
Setti SE, Das N, Raymick J, Hanig J, Sarkar S
Metabolic brain disease 2022 Mar;37(3):639-651
Metabolic brain disease 2022 Mar;37(3):639-651
CN-3 increases TMZ sensitivity and induces ROS-dependent apoptosis and autophagy in TMZ-resistance glioblastoma.
Xue YY, Lu YY, Sun GQ, Fang F, Ji YQ, Tang HF, Qiu PC, Cheng G
Journal of biochemical and molecular toxicology 2022 Mar;36(3):e22973
Journal of biochemical and molecular toxicology 2022 Mar;36(3):e22973
Vitamin D3 promotes autophagy in THP-1 cells infected with Mycobacterium tuberculosis.
Wu Y, Lin X, Song F, Xue D, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):240
Experimental and therapeutic medicine 2022 Mar;23(3):240
Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.
Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J
Biological trace element research 2022 Mar;200(3):1312-1320
Biological trace element research 2022 Mar;200(3):1312-1320
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Zhou H, Zhang J, Yan Z, Qu M, Zhang G, Han J, Wang F, Sun K, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
Deacetylation of ZKSCAN3 by SIRT1 induces autophagy and protects SN4741 cells against MPP(+)-induced oxidative stress.
Wu X, Ren Y, Wen Y, Lu S, Li H, Yu H, Li W, Zou F
Free radical biology & medicine 2022 Mar;181:82-97
Free radical biology & medicine 2022 Mar;181:82-97
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
Liu J, Wang L, Ge L, Sun W, Song Z, Lu X, Jin C, Wu S, Yang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Zhang J, Shang L, Jiang W, Wu W
Bioengineered 2022 Mar;13(3):7904-7918
Bioengineered 2022 Mar;13(3):7904-7918
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Wang C, Tang Z, Zhang Z, Liu T, Zhang J, Huang H, Li Y
Bioengineered 2022 Mar;13(3):7328-7339
Bioengineered 2022 Mar;13(3):7328-7339
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Ren C, Xu Y, Liu H, Wang Z, Ma T, Li Z, Sun L, Huang Q, Zhang K, Zhang C, Cui Y, Wang Q, Lu Y
Bioengineered 2022 Mar;13(3):5262-5276
Bioengineered 2022 Mar;13(3):5262-5276
c-MYC-mediated TRIB3/P62(+) aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2.
Su MX, Xu YL, Jiang XM, Huang MY, Zhang LL, Yuan LW, Xu XH, Zhu Q, Gao JL, Lu JH, Chen X, Huang MQ, Wang Y, Lu JJ
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1240-1253
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1240-1253
Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
Lu Y, Zhong W, Liu Y, Chen W, Zhang J, Zeng Z, Huang H, Qiao Y, Wan X, Meng X, Cai S, Dong H
International immunopharmacology 2022 Mar;104:108504
International immunopharmacology 2022 Mar;104:108504
Involvement of NEAT1/PINK1-mediated mitophagy in chronic obstructive pulmonary disease induced by cigarette smoke or PM(2.5).
Lin Q, Zhang CF, Guo JL, Su JL, Guo ZK, Li HY
Annals of translational medicine 2022 Mar;10(6):277
Annals of translational medicine 2022 Mar;10(6):277
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Ding XQ, Jian TY, Gai YN, Niu GT, Liu Y, Meng XH, Li J, Lyu H, Ren BR, Chen J
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2.
Cai B, Ma M, Zhang J, Wang Z, Kong S, Zhou Z, Lian L, Zhang J, Li J, Wang Y, Li H, Zhang X, Nie Q
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
Molecular therapy. Nucleic acids 2022 Mar 8;27:319-334
LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer.
Zhan L, Zhang J, Zhang J, Liu X, Zhu S, Shi Y, He Y, Wang W, Fan Y, Tang Z, Chen G, Wei B, Cao Y
Cancer letters 2022 Mar 31;529:37-52
Cancer letters 2022 Mar 31;529:37-52
Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma.
Li D, Yao Y, Rao Y, Huang X, Wei L, You Z, Zheng G, Hou X, Su Y, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Journal of experimental & clinical cancer research : CR 2022 Mar 30;41(1):116
Journal of experimental & clinical cancer research : CR 2022 Mar 30;41(1):116
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
Xu Z, Zhang M, Li X, Wang Y, Du R
International journal of molecular sciences 2022 Mar 30;23(7)
International journal of molecular sciences 2022 Mar 30;23(7)
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Gu X, Zhang L, Sun W, Liu K, Xu H, Wu P, Gui M, Qu W
Chemical research in toxicology 2022 Mar 21;35(3):392-401
Chemical research in toxicology 2022 Mar 21;35(3):392-401
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Zhong Y, Liu J, Sun D, Guo T, Yao Y, Xia X, Shi C, Peng X
Food & function 2022 Mar 21;13(6):3660-3673
Food & function 2022 Mar 21;13(6):3660-3673
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
Read ML, Brookes K, Thornton CEM, Fletcher A, Nieto HR, Alshahrani M, Khan R, Borges de Souza P, Zha L, Webster JRM, Alderwick LJ, Campbell MJ, Boelaert K, Smith VE, McCabe CJ
Cell chemical biology 2022 Mar 17;29(3):502-516.e7
Cell chemical biology 2022 Mar 17;29(3):502-516.e7
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Guan X, Yan Q, Wang D, Du G, Zhou J
Nutrients 2022 Mar 16;14(6)
Nutrients 2022 Mar 16;14(6)
The regulation of autophagy by the miR-199a-5p/p62 axis was a potential mechanism of small cell lung cancer cisplatin resistance.
Li T, Zhang H, Wang Z, Gao S, Zhang X, Zhu H, Wang N, Li H
Cancer cell international 2022 Mar 15;22(1):120
Cancer cell international 2022 Mar 15;22(1):120
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
He Z, Cai K, Zeng Z, Lei S, Cao W, Li X
Cell death & disease 2022 Mar 14;13(3):233
Cell death & disease 2022 Mar 14;13(3):233
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Jiang Y, Li H, Huang P, Li S, Li B, Huo L, Zhong J, Pan Z, Li Y, Xia X
Journal of ethnopharmacology 2022 Mar 1;285:114859
Journal of ethnopharmacology 2022 Mar 1;285:114859
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Zhang Y, Wu Z, Huang Z, Liu Y, Chen X, Zhao X, He H, Deng Y
Brain research 2022 Mar 1;1778:147768
Brain research 2022 Mar 1;1778:147768
Acetaldehyde Induces Cytotoxicity via Triggering Mitochondrial Dysfunction and Overactive Mitophagy.
Yan T, Zhao Y, Jiang Z, Chen J
Molecular neurobiology 2022 Jun;59(6):3933-3946
Molecular neurobiology 2022 Jun;59(6):3933-3946
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Liu H, He S, Wang J, Li C, Liao Y, Zou Q, Chen R
Neurochemical research 2022 Jun;47(6):1574-1587
Neurochemical research 2022 Jun;47(6):1574-1587
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
Zhou J, Huang Q, Wang L, Li E, Huang W, Xiang Z
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2022 Jun;38(5):331-338
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2022 Jun;38(5):331-338
The role of NOTCH2NLC in Parkinson's disease: A clinical, neuroimaging, and pathological study.
Liu P, Yang D, Zhang F, Chen S, Xie F, Luo Y, Wang H, Chen Y, Lin Z, Wang L, Chen X, Wang B, Wu S, Ouyang Z, Cen Z, Luo W
European journal of neurology 2022 Jun;29(6):1610-1618
European journal of neurology 2022 Jun;29(6):1610-1618
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Wang T, Zhang L, Liang W, Liu S, Deng W, Liu Y, Liu Y, Song M, Guo K, Zhang Y
Autophagy 2022 Jun;18(6):1433-1449
Autophagy 2022 Jun;18(6):1433-1449
Autophagy deficiency activates rDNA transcription.
Xu Y, Wu Y, Wang L, Ren Z, Song L, Zhang H, Qian C, Wang Q, He Z, Wan W
Autophagy 2022 Jun;18(6):1338-1349
Autophagy 2022 Jun;18(6):1338-1349
m(6)A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.
Liang D, Lin WJ, Ren M, Qiu J, Yang C, Wang X, Li N, Zeng T, Sun K, You L, Yan L, Wang W
Autophagy 2022 Jun;18(6):1318-1337
Autophagy 2022 Jun;18(6):1318-1337
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Li S, Ma Y, Ye S, Su Y, Hu D, Xiao F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113071
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113071
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Ren K, He J, Qiu Y, Xu Z, Wang X, Li J, Zang S, Yang Y, Li J, Long Y, Zhang Z, Li M, He Q
Acta biomaterialia 2022 Jun;145:185-199
Acta biomaterialia 2022 Jun;145:185-199
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
Lloyd GM, Sorrentino ZA, Quintin S, Gorion KM, Bell BM, Paterno G, Long B, Prokop S, Giasson BI
Acta neuropathologica 2022 Jun;143(6):663-685
Acta neuropathologica 2022 Jun;143(6):663-685
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
Ye Z, Xia Y, Zhou X, Li B, Yu W, Ruan Y, Li H, Ning J, Chen L, Rao T, Cheng F
International immunopharmacology 2022 Jun;107:108677
International immunopharmacology 2022 Jun;107:108677
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171
Critical care (London, England) 2022 Jun 9;26(1):171
Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.
Wen XP, Long G, Zhang YZ, Huang H, Liu TH, Wan QQ
Proteome science 2022 Jun 9;20(1):10
Proteome science 2022 Jun 9;20(1):10
Isogenic GAA-KO Murine Muscle Cell Lines Mimicking Severe Pompe Mutations as Preclinical Models for the Screening of Potential Gene Therapy Strategies.
Aguilar-González A, González-Correa JE, Barriocanal-Casado E, Ramos-Hernández I, Lerma-Juárez MA, Greco S, Rodríguez-Sevilla JJ, Molina-Estévez FJ, Montalvo-Romeral V, Ronzitti G, Sánchez-Martín RM, Martín F, Muñoz P
International journal of molecular sciences 2022 Jun 4;23(11)
International journal of molecular sciences 2022 Jun 4;23(11)
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Attenuation of histone H4 lysine 16 acetylation (H4K16ac) elicits a neuroprotection against ischemic stroke by alleviating the autophagic/lysosomal dysfunction in neurons at the penumbra.
Lingling D, Miaomiao Q, Yili L, Hongyun H, Yihao D
Brain research bulletin 2022 Jun 15;184:24-33
Brain research bulletin 2022 Jun 15;184:24-33
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Dong J, Zhang KJ, Li GC, Chen XR, Lin JJ, Li JW, Lv ZY, Deng ZZ, Dai J, Cao W, Jiang Q
Acta pharmacologica Sinica 2022 Jul;43(7):1793-1802
Acta pharmacologica Sinica 2022 Jul;43(7):1793-1802
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Shi YX, Sun ZW, Jia DL, Wang HB
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Abnormal accumulation of OFD1 in endometrial cancer with poor prognosis inhibits ciliogenesis.
Kojima R, Hassan E, Ozawa F, Yamada-Namikawa C, Ogawa S, Mase S, Goto S, Nishikawa R, Inagaki H, Kato Y, Sugiura-Ogasawara M
Oncology letters 2022 Jul;24(1):214
Oncology letters 2022 Jul;24(1):214
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Tian W, Liu SY, Zhang M, Meng JR, Tang N, Feng YD, Sun Y, Gao YY, Zhou L, Cao W, Li XQ
Pharmacological research 2022 Jul;181:106262
Pharmacological research 2022 Jul;181:106262
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2022 Jul;18(7):1599-1612
Autophagy 2022 Jul;18(7):1599-1612
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Jin Z, Chang B, Wei Y, Yang Y, Zhang H, Liu J, Piao L, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
Multifunctional theranostic nanoplatform loaded with autophagy inhibitor for enhanced photothermal cancer therapy under mild near-infrared irradiation.
Shi M, Liu Y, Huang J, Chen Z, Ni C, Lu J, Zhang Y, Liu Z, Bai J
Biomaterials advances 2022 Jul;138:212919
Biomaterials advances 2022 Jul;138:212919
sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death.
Wu Z, Xu Z, Zhou X, Li H, Zhao L, Lv Y, Guo Y, Shen G, He Y, Lei P
Cell death & disease 2022 Jul 7;13(7):587
Cell death & disease 2022 Jul 7;13(7):587
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Cao J, Chen C, Chen Q, Gao Y, Zhao Z, Yuan Q, Li A, Yang S, He Y, Zu X, Liu J
Journal of translational medicine 2022 Jul 6;20(1):307
Journal of translational medicine 2022 Jul 6;20(1):307
Aggregation-Induced Emission Photosensitizer Synergizes Photodynamic Therapy and the Inhibition of the NF-κB Signaling Pathway to Overcome Hypoxia in Breast Cancer.
Wang J, Wu H, Zhao Q, Zou Y, Ding D, Yin H, Xu H
ACS applied materials & interfaces 2022 Jul 6;14(26):29613-29625
ACS applied materials & interfaces 2022 Jul 6;14(26):29613-29625
Punicalagin Protects against Diabetic Liver Injury by Upregulating Mitophagy and Antioxidant Enzyme Activities.
Zhang Y, Tan X, Cao Y, An X, Chen J, Yang L
Nutrients 2022 Jul 6;14(14)
Nutrients 2022 Jul 6;14(14)
The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.
Guo S, Qi M, Li H, Cui Y, Qi C, Cheng G, Lv M, Zheng P, Liu J
Life (Basel, Switzerland) 2022 Jul 25;12(8)
Life (Basel, Switzerland) 2022 Jul 25;12(8)
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294
Stem cell research & therapy 2022 Jul 15;13(1):294
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis.
Hou B, Huang H, Li Y, Liang J, Xi Z, Jiang X, Liu L, Li E
Cell death discovery 2022 Jul 13;8(1):319
Cell death discovery 2022 Jul 13;8(1):319
Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway.
Liu Y, Li H, Zheng Z, Niu A, Liu S, Li W, Ren P, Liu Y, Inam M, Guan L, Ma H
International journal of biological macromolecules 2022 Jul 1;212:257-274
International journal of biological macromolecules 2022 Jul 1;212:257-274
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis.
Chen Y, Zhao H, Liang W, Jiang E, Zhou X, Shao Z, Liu K, Shang Z
Oncogene 2022 Jan;41(5):634-646
Oncogene 2022 Jan;41(5):634-646
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Zhang C, Tang Q, Xia H, Xu H, Bi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22121
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense.
Xie W, Jin S, Zhang C, Yang S, Wu Y, Zhao Y, Songyang Z, Cui J
Cell death and differentiation 2022 Jan;29(1):40-53
Cell death and differentiation 2022 Jan;29(1):40-53
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Xu Q, Zhang H, Liu H, Han Y, Qiu W, Li Z
Biomaterials 2022 Jan;280:121287
Biomaterials 2022 Jan;280:121287
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Jia S, He D, Liang X, Cheng P, Liu J, Chen M, Wang C, Zhang H, Meng C
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Ma C, Wu H, Yang G, Xiang J, Feng K, Zhang J, Hua Y, Kang L, Fan G, Yang S
British journal of pharmacology 2022 Jan;179(2):252-269
British journal of pharmacology 2022 Jan;179(2):252-269
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Zhong Y, Luo R, Liu Q, Zhu J, Lei M, Liang X, Wang X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
Li J, Li M, Li L, Ma J, Yao C, Yao S
Molecular immunology 2022 Jan;141:318-327
Molecular immunology 2022 Jan;141:318-327
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
Yu H, Cen J, Lin X, Cheng H, Seifert O
Immunity, inflammation and disease 2022 Jan;10(1):70-77
Immunity, inflammation and disease 2022 Jan;10(1):70-77
Mitochondrial dysfunction is involved in the cellular activity inhibition by eleutheroside B in SMMC-7721 and HeLa cells.
Sun S, Zhang Y, Xu W, Wang B, Chen J
Human & experimental toxicology 2022 Jan-Dec;41:9603271221089006
Human & experimental toxicology 2022 Jan-Dec;41:9603271221089006
PM2.5 activated NLRP3 inflammasome and IL-1β release in MH-S cells by facilitating autophagy via activating Wnt5a.
Yuan G, Liu Y, Wang Z, Wang X, Han Z, Yan X, Meng A
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221137464
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221137464
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Li S, Ma Y, Ye S, Hu D, Xiao F
Journal of hazardous materials 2022 Jan 5;421:126758
Journal of hazardous materials 2022 Jan 5;421:126758
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Yang L, Wang Q, Zhao Q, Yang F, Liu T, Huang X, Yan Q, Yang X
Aging 2022 Jan 4;14(1):316-329
Aging 2022 Jan 4;14(1):316-329
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Wu L, Shen B, Li J, Zhang H, Zhang K, Yang Y, Zu Z, Shen D, Luo M
Diagnostic pathology 2022 Jan 20;17(1):13
Diagnostic pathology 2022 Jan 20;17(1):13
Feeder-supported in vitro exercise model using human satellite cells from patients with sporadic inclusion body myositis.
Li Y, Chen W, Ogawa K, Koide M, Takahashi T, Hagiwara Y, Itoi E, Aizawa T, Tsuchiya M, Izumi R, Suzuki N, Aoki M, Kanzaki M
Scientific reports 2022 Jan 20;12(1):1082
Scientific reports 2022 Jan 20;12(1):1082
Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice.
Yan J, Sun W, Shen M, Zhang Y, Jiang M, Liu A, Ma H, Lai X, Wu J
Cell death discovery 2022 Jan 17;8(1):28
Cell death discovery 2022 Jan 17;8(1):28
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Xi H, Ren F, Li Y, Xian M, Wang L, Hu J
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Zhang Y, Han X, Tang Y, Zhang J, Hu Z, Xu W, Yao P, Niu Q
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Biotinylated curcumin as a novel chemosensitizer enhances naphthalimide-induced autophagic cell death in breast cancer cells.
Shao C, Wu J, Han S, Liu Y, Su Z, Zhu HL, Liu HK, Qian Y
European journal of medicinal chemistry 2022 Jan 15;228:114029
European journal of medicinal chemistry 2022 Jan 15;228:114029
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Liu X, Chen J, Long X, Lan J, Liu X, Zhou M, Zhang S, Zhou J
Cell death & disease 2022 Jan 10;13(1):43
Cell death & disease 2022 Jan 10;13(1):43
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Kan Y, Song M, Cui X, Yang Q, Zang Y, Li Q, Li Y, Cai W, Chen Y, Weng X, Wang Y, Zhu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2022 Feb;49(2):1223-1232
Molecular biology reports 2022 Feb;49(2):1223-1232
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
Hou B, Li E, Liang J, Liu S, Yang H, Liu L, Jiang X
Cell biology international 2022 Feb;46(2):311-322
Cell biology international 2022 Feb;46(2):311-322
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Journal of applied toxicology : JAT 2022 Feb;42(2):230-243
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
Wu P, Dong Y, Chen J, Guan T, Cao B, Zhang Y, Qi Y, Guan Z, Wang Y
Neurotoxicity research 2022 Feb;40(1):286-297
Neurotoxicity research 2022 Feb;40(1):286-297
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Wen C, Lin L, Zou R, Lin F, Liu Y
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner.
Huang W, Li N, Zhang Y, Wang X, Yin M, Lei QY
Autophagy 2022 Feb;18(2):309-319
Autophagy 2022 Feb;18(2):309-319
Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
Liu M, Lu J, Yang S, Chen Y, Yu J, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112811
Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver.
Zhu Y, Zhang J, Yao X, Qiu T, Jiang L, Wang N, Shi Y, Wu C, Yuan W, Yang G, Liu X, Bai J, Men L, Sun X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112771
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112771
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Liu Z, Yun B, Han Y, Jiang Z, Zhu H, Ren F, Li Z
Advanced healthcare materials 2022 Feb;11(3):e2102042
Advanced healthcare materials 2022 Feb;11(3):e2102042
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Packialakshmi B, Stewart IJ, Burmeister DM, Feng Y, McDaniel DP, Chung KK, Zhou X
Physiological reports 2022 Feb;10(3):e15181
Physiological reports 2022 Feb;10(3):e15181
Improving Lipophagy by Restoring Rab7 Cycle: Protective Effects of Quercetin on Ethanol-Induced Liver Steatosis.
Lin H, Guo X, Liu J, Liu P, Mei G, Li H, Li D, Chen H, Chen L, Zhao Y, Jiang C, Yu Y, Liu W, Yao P
Nutrients 2022 Feb 4;14(3)
Nutrients 2022 Feb 4;14(3)
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas.
Gao L, Zhang Q, Li S, Zheng J, Ren W, Zhi K
Cell death & disease 2022 Feb 26;13(2):192
Cell death & disease 2022 Feb 26;13(2):192
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
Wang Y, Xu J, Wang Y, Xiang L, He X
Food & function 2022 Feb 21;13(4):2200-2215
Food & function 2022 Feb 21;13(4):2200-2215
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Feb 2;30(2):932-946
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Feb 2;30(2):932-946
RIPK1-RIPK3 mediates myocardial fibrosis in type 2 diabetes mellitus by impairing autophagic flux of cardiac fibroblasts.
Qiao S, Hong L, Zhu Y, Zha J, Wang A, Qiu J, Li W, Wang C, An J, Zhang H
Cell death & disease 2022 Feb 14;13(2):147
Cell death & disease 2022 Feb 14;13(2):147
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Chaoqun H, Rong Y, Yunpeng P, Xiaole Z, Wanli G, Chenyuan S, Dongya H, Yi M, Qiang L
Tissue & cell 2022 Dec;79:101940
Tissue & cell 2022 Dec;79:101940
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Li Z, Wu Z, Xi X, Zhao F, Liu H, Liu D
Journal of periodontal research 2022 Dec;57(6):1169-1182
Journal of periodontal research 2022 Dec;57(6):1169-1182
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
Jia Z, Liu J, Wang J
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Gao Y, Zheng X, Chang B, Lin Y, Huang X, Wang W, Ding S, Zhan W, Wang S, Xiao B, Huo L, Yu Y, Chen Y, Gong R, Wu Y, Zhang R, Zhong L, Wang X, Chen Q, Gao S, Jiang Z, Wei D, Kang T
Cell research 2022 Dec;32(12):1086-1104
Cell research 2022 Dec;32(12):1086-1104
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
Zhao Q, Pan W, Li J, Yu S, Liu Y, Zhang X, Qu R, Zhang Q, Li B, Yan X, Ren X, Qiu Y
Chemosphere 2022 Dec;308(Pt 2):136341
Chemosphere 2022 Dec;308(Pt 2):136341
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
Xu Z, Li X, Ding Z, Zhang Y, Peng Z, Yang X, Cao W, Du R
The FEBS journal 2022 Dec;289(23):7545-7560
The FEBS journal 2022 Dec;289(23):7545-7560
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.
Tan Z, Ren H, Liu Y, Yang H, Luo Q, Deng X
Experimental and therapeutic medicine 2022 Dec;24(6):737
Experimental and therapeutic medicine 2022 Dec;24(6):737
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
Yan G, Li X, Zheng Z, Gao W, Chen C, Wang X, Cheng Z, Yu J, Zou G, Farooq MZ, Zhu X, Zhu W, Zhong Q, Yan X
Autophagy 2022 Dec;18(12):2799-2816
Autophagy 2022 Dec;18(12):2799-2816
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation.
Deng T, Hu B, Wang X, Ding S, Lin L, Yan Y, Peng X, Zheng X, Liao M, Jin Y, Dong W, Gu J, Zhou J
Autophagy 2022 Dec;18(12):2781-2798
Autophagy 2022 Dec;18(12):2781-2798
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
Zang X, Wang J, Xia Y, Li J, Chen L, Gu Y, Shen X
Leukemia research 2022 Dec;123:106967
Leukemia research 2022 Dec;123:106967
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Han F, Shen L, Ma H, Wang L, Guo H, Wu X
International immunopharmacology 2022 Dec;113(Pt A):109279
International immunopharmacology 2022 Dec;113(Pt A):109279
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Li X, Chen H, Zhang Z, Duan J, Hua R, Li X, Yang L, Cheng J, Li Q
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:381-390
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:381-390
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, Mao X, Wu J, Xu Y, Xiong Q, Chen Z, Zhang B, Han J
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Luo L, Liang Y, Fu Y, Liang Z, Zheng J, Lan J, Shen F, Huang Z
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.
Zheng Z, Yan G, Li X, Fei Y, Sun L, Yu H, Niu Y, Gao W, Zhong Q, Yan X
Cell reports 2022 Dec 20;41(12):111850
Cell reports 2022 Dec 20;41(12):111850
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
Croft CL, Paterno G, Vause AR, Rowe LA, Ryu DH, Goodwin MS, Moran CA, Cruz PE, Giasson BI, Golde TE
NPJ Parkinson's disease 2022 Dec 19;8(1):173
NPJ Parkinson's disease 2022 Dec 19;8(1):173
Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes.
Wang L, Zheng P, Cui Y, Zhang Z, Song K, Liu Y, Liu J
Ecotoxicology and environmental safety 2022 Dec 15;248:114315
Ecotoxicology and environmental safety 2022 Dec 15;248:114315
The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy.
Jiang S, Xia N, Luo J, Zhang Y, Cao Q, Zhang J, Wang Y, Zhao Y, Zheng W, Chen N, Meurens F, Li X, Zhu J
Journal of virology 2022 Dec 14;96(23):e0147622
Journal of virology 2022 Dec 14;96(23):e0147622
The SPATA2/CYLD pathway contributes to doxorubicin-induced cardiomyocyte ferroptosis via enhancing ferritinophagy.
Zhou YJ, Duan DQ, Lu LQ, Tang LJ, Zhang XJ, Luo XJ, Peng J
Chemico-biological interactions 2022 Dec 1;368:110205
Chemico-biological interactions 2022 Dec 1;368:110205
Lactoferrin alleviates spermatogenesis dysfunction caused by bisphenol A and cadmium via ameliorating disordered autophagy, apoptosis and oxidative stress.
He H, Chen X, Li X, Yang K, Li J, Shi H
International journal of biological macromolecules 2022 Dec 1;222(Pt A):1048-1062
International journal of biological macromolecules 2022 Dec 1;222(Pt A):1048-1062
Phosphorylated alpha-synuclein in Iba1-positive macrophages in the skin of patients with Parkinson's disease.
Oizumi H, Yamasaki K, Suzuki H, Ohshiro S, Saito Y, Murayama S, Sugimura Y, Hasegawa T, Fukunaga K, Takeda A
Annals of clinical and translational neurology 2022 Aug;9(8):1136-1146
Annals of clinical and translational neurology 2022 Aug;9(8):1136-1146
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
Liang L, Wang H, Hu Y, Bian H, Xiao L, Wang G
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, Nesvizhskii AI, Paulson HL, Wang Y
The Journal of biological chemistry 2022 Aug;298(8):102219
The Journal of biological chemistry 2022 Aug;298(8):102219
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
Zhang B, Li J, Zong X, Wang J, Xin L, Song H, Zhang W, Koda S, Hua H, Zhang B, Yu Q, Zheng KY, Yan C
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Inhibition of autophagy by 3-methyladenine promotes migration and invasion of colon cancer cells through epithelial mesenchymal transformation.
Zhang X, Wang H, Yu M, Ma K, Ning L
Translational cancer research 2022 Aug;11(8):2834-2842
Translational cancer research 2022 Aug;11(8):2834-2842
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
Xiu T, Guo Q, Jing F, Shi Y, Jing F
Translational cancer research 2022 Aug;11(8):2487-2500
Translational cancer research 2022 Aug;11(8):2487-2500
The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.
Cheng G, Zhang S, Lv M, Qi C, Fan R, Guo X, Liu J, Zhao X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154212
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154212
Stellettin B-Induced Oral Cancer Cell Death via Endoplasmic Reticulum Stress-Mitochondrial Apoptotic and Autophagic Signaling Pathway.
Kuo TJ, Jean YH, Shih PC, Cheng SY, Kuo HM, Lee YT, Lai YC, Tseng CC, Chen WF, Wen ZH
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
Liao Z, Gong Z, Wang Z, Yang W, Liu W, Hou L, Liu X, Hua J, Wang B, Li N
Cells 2022 Aug 30;11(17)
Cells 2022 Aug 30;11(17)
Sesamin Ameliorates Fine Particulate Matter (PM(2.5))-Induced Lung Injury via Suppression of Apoptosis and Autophagy in Rats.
Ren J, Li X, Zhu S, Yin B, Guo Z, Cui Q, Song J, Pei H, Ma Y
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9489-9498
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9489-9498
ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function.
Pant DC, Parameswaran J, Rao L, Loss I, Chilukuri G, Parlato R, Shi L, Glass JD, Bassell GJ, Koch P, Yilmaz R, Weishaupt JH, Gennerich A, Jiang J
EMBO reports 2022 Aug 3;23(8):e54234
EMBO reports 2022 Aug 3;23(8):e54234
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
Li S, Gao L, Liu J, Guo C, Zheng J, Zhi K, Ren W
Cell death discovery 2022 Aug 25;8(1):373
Cell death discovery 2022 Aug 25;8(1):373
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Zhang M, Qiu H, Mao L, Wang B, Li N, Fan Y, Weng P, Hu S, Dong X, Qin X, Chen C, Zou Z, Yu C, Zhang J
Cell death & disease 2022 Aug 25;13(8):733
Cell death & disease 2022 Aug 25;13(8):733
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Zhang K, Wang Q, Zhao D, Liu Z
Biochemical genetics 2022 Apr;60(2):770-789
Biochemical genetics 2022 Apr;60(2):770-789
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Yu K, Tan Z, Xin Y
Molecular biology reports 2022 Apr;49(4):2785-2793
Molecular biology reports 2022 Apr;49(4):2785-2793
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Zeng L, He J, Liu C, Zhang F, Zhang Z, Chen H, Wang Q, Ding X, Luo H
Inflammation 2022 Apr;45(2):725-738
Inflammation 2022 Apr;45(2):725-738
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Liu K, Qiu D, Liang X, Huang Y, Wang Y, Jia X, Li K, Zhao J, Du C, Qiu X, Cui J, Xiao Z, Qin Y, Zhang Q
Autophagy 2022 Apr;18(4):860-876
Autophagy 2022 Apr;18(4):860-876
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer.
Gong L, Zhang Y, Zhao J, Zhang Y, Tu K, Jiao L, Xu Q, Zhang M, Han S
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107656
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107656
PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway.
Du J, Xu Q, Zhao H, Jia X, Ba N, Peng F, Zhang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112665
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112665
S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia.
Oh CK, Dolatabadi N, Cieplak P, Diaz-Meco MT, Moscat J, Nolan JP, Nakamura T, Lipton SA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Apr 6;42(14):3011-3024
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Apr 6;42(14):3011-3024
Interpreting the Pharmacological Mechanisms of Sho-saiko-to on Thyroid Carcinoma through Combining Network Pharmacology and Experimental Evaluation.
Wang K, Qian R, Li H, Wang C, Ding Y, Gao Z
ACS omega 2022 Apr 5;7(13):11166-11176
ACS omega 2022 Apr 5;7(13):11166-11176
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
Usman M, Li Y, Ke Y, Chhetri G, Islam MA, Wang Z, Li X
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
Luo R, Liang H, Zhang W, Li G, Zhao K, Hua W, Song Y, Yang C
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy.
Liu B, Sun T, Li H, Qiu S, Li Y, Zhang D
Cell death & disease 2022 Apr 23;13(4):399
Cell death & disease 2022 Apr 23;13(4):399
Long noncoding RNA ZFP36L2-AS functions as a metabolic modulator to regulate muscle development.
Cai B, Ma M, Zhang J, Kong S, Zhou Z, Li Z, Abdalla BA, Xu H, Zhang X, Lawal RA, Nie Q
Cell death & disease 2022 Apr 21;13(4):389
Cell death & disease 2022 Apr 21;13(4):389
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Wu M, Cong Y, Wang K, Yu H, Zhang X, Ma M, Duan Z, Pei X
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
Xu L, Su B, Mo L, Zhao C, Zhao Z, Li H, Hu Z, Li J
International journal of molecular sciences 2022 Apr 1;23(7)
International journal of molecular sciences 2022 Apr 1;23(7)
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963
Neuropharmacology 2022 Apr 1;207:108963
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Jiang XJ, Wu YQ, Ma R, Chang YM, Li LL, Zhu JH, Liu GP, Li G
Frontiers in cell and developmental biology 2021;9:736267
Frontiers in cell and developmental biology 2021;9:736267
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Wang Y, He M, Li X, Chai J, Jiang Q, Peng C, He G, Huang W
Frontiers in chemistry 2021;9:700956
Frontiers in chemistry 2021;9:700956
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Li C, Zhu Y, Wu Y, Fu M, Wu Y, Wu Y, Qiu Y, Zhang H, Ding M
Frontiers in medicine 2021;8:813047
Frontiers in medicine 2021;8:813047
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Zhu X, Chen Y, Lin M, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy.
Li S, Jiang Y, Xing X, Lin R, Li Q, Zhou W, Qiu W, Zheng W
Oxidative medicine and cellular longevity 2021;2021:7654143
Oxidative medicine and cellular longevity 2021;2021:7654143
Pentoxifylline Can Reduce the Inflammation Caused by LPS after Inhibiting Autophagy in RAW264.7 Macrophage Cells.
Ruan D, Deng S, Liu Z, He J
BioMed research international 2021;2021:6698366
BioMed research international 2021;2021:6698366
Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration.
Hu S, Zhang C, Qian T, Bai Y, Chen L, Chen J, Huang C, Xie C, Wang X, Jin H
Oxidative medicine and cellular longevity 2021;2021:6694964
Oxidative medicine and cellular longevity 2021;2021:6694964
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Zhao R, Wang B, Wang D, Wu B, Ji P, Tan D
Oxidative medicine and cellular longevity 2021;2021:6675264
Oxidative medicine and cellular longevity 2021;2021:6675264
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer's Disease by Network Pharmacology and Experimental Validation.
Jiang Y, Li S, Xie X, Li H, Huang P, Li B, Huo L, Zhong J, Li Y, Xia X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5730812
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5730812
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
Song S, Bao S, Zhang C, Zhang J, Lv J, Li X, Chudhary M, Ren X, Kong L
Oxidative medicine and cellular longevity 2021;2021:5587340
Oxidative medicine and cellular longevity 2021;2021:5587340
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Luo R, Li S, Li G, Lu S, Zhang W, Liu H, Lei J, Ma L, Ke W, Liao Z, Wang B, Song Y, Wang K, Zhang Y, Yang C
Oxidative medicine and cellular longevity 2021;2021:3843145
Oxidative medicine and cellular longevity 2021;2021:3843145
TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma.
Lu H, Zhu C, Ruan Y, Fan L, Wei K, Yang Z, Chen Q
Analytical cellular pathology (Amsterdam) 2021;2021:3081491
Analytical cellular pathology (Amsterdam) 2021;2021:3081491
HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats.
Tang Z, Chen J, Zhang Z, Bi J, Xu R, Lin Q, Wang Z
Oxidative medicine and cellular longevity 2021;2021:1764929
Oxidative medicine and cellular longevity 2021;2021:1764929
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
Jiang L, Shen X, Dun Y, Xie M, Fu S, Zhang W, Qiu L, Ripley-Gonzalez JW, Liu S
International journal of medical sciences 2021;18(7):1680-1686
International journal of medical sciences 2021;18(7):1680-1686
IFI30 expression predicts patient prognosis in breast cancer and dictates breast cancer cells proliferation via regulating autophagy.
Fan Y, Wang X, Li Y
International journal of medical sciences 2021;18(14):3342-3352
International journal of medical sciences 2021;18(14):3342-3352
The Anti-apoptosis Effect of Single Electroacupuncture Treatment via Suppressing Neuronal Autophagy in the Acute Stage of Ischemic Stroke Without Infarct Alleviation.
Xing Y, Zhang M, Wang MM, Feng YS, Dong F, Zhang F
Frontiers in cellular neuroscience 2021;15:633280
Frontiers in cellular neuroscience 2021;15:633280
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
Yan X, Tian R, Sun J, Zhao Y, Liu B, Su J, Li M, Sun W, Xu X
Frontiers in pharmacology 2021;12:788667
Frontiers in pharmacology 2021;12:788667
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Li M, Zhao X, Yong H, Shang B, Lou W, Wang Y, Bai J
Frontiers in pharmacology 2021;12:778698
Frontiers in pharmacology 2021;12:778698
Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.
Li G, Zhong Y, Wang W, Jia X, Zhu H, Jiang W, Song Y, Xu W, Wu S
Frontiers in pharmacology 2021;12:770667
Frontiers in pharmacology 2021;12:770667
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Xiong M, Hu W, Tan Y, Yu H, Zhang Q, Zhao C, Yi Y, Wang Y, Wu Y, Wu M
Frontiers in physiology 2021;12:748040
Frontiers in physiology 2021;12:748040
SC75741, A Novel c-Abl Inhibitor, Promotes the Clearance of TDP25 Aggregates via ATG5-Dependent Autophagy Pathway.
Zhou D, Yan H, Yang S, Zhang Y, Xu X, Cen X, Lei K, Xia H
Frontiers in pharmacology 2021;12:741219
Frontiers in pharmacology 2021;12:741219
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Liu Y, Zhong W, Zhang J, Chen W, Lu Y, Qiao Y, Zeng Z, Huang H, Cai S, Dong H
Frontiers in pharmacology 2021;12:739220
Frontiers in pharmacology 2021;12:739220
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Zhang C, Wang X, Sun J, Guo M, Zhang X, Wu Y
Frontiers in microbiology 2021;12:733385
Frontiers in microbiology 2021;12:733385
Lactobacillus rhamnosus GR-1 Prevents Escherichia coli-Induced Apoptosis Through PINK1/Parkin-Mediated Mitophagy in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Frontiers in immunology 2021;12:715098
Frontiers in immunology 2021;12:715098
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Yang W, Su J, Li M, Li T, Wang X, Zhao M, Hu X
Frontiers in pharmacology 2021;12:709526
Frontiers in pharmacology 2021;12:709526
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in China.
Ma X, Xu L, Ji S, Li Y, Bu B
Frontiers in neurology 2021;12:670784
Frontiers in neurology 2021;12:670784
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway.
Li X, Huang K, Liu X, Ruan H, Ma L, Liang J, Cui Y, Wang Y, Wu S, Li H, Wei Y, Li Z, Gao J, Yang B, Li X, Yang G, Zhou H, Yang C
Frontiers in pharmacology 2021;12:639574
Frontiers in pharmacology 2021;12:639574
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Su J, Gao C, Xie L, Fan Y, Shen Y, Huang Q, Wang N, Xu Y, Yang N, Gui D
Frontiers in pharmacology 2021;12:638422
Frontiers in pharmacology 2021;12:638422
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway.
Li L, Li Q, Huang W, Han Y, Tan H, An M, Xiang Q, Zhou R, Yang L, Cheng Y
Frontiers in pharmacology 2021;12:589273
Frontiers in pharmacology 2021;12:589273
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Dai H, Ma B, Dai X, Pang J, Wang J, Zhao Y, Wang M, Zhang H, Gao H, Qian S, Tian F, Sun X
Frontiers in pharmacology 2021;12:585286
Frontiers in pharmacology 2021;12:585286
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Liu X, Wang S, Zheng H, Liu Q, Shen T, Wang X, Ren D
American journal of cancer research 2021;11(7):3496-3514
American journal of cancer research 2021;11(7):3496-3514
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Liu WJ, Pan PY, Sun Y, Wang JB, Zhou H, Xie X, Duan ZY, Dong HY, Chen WN, Zhang LD, Wang C
Frontiers in oncology 2021;11:794735
Frontiers in oncology 2021;11:794735
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Ning H, Zhang W, Kang J, Ding T, Liang X, Lu Y, Guo C, Sun W, Wang H, Bai Y, Shen L
Frontiers in cellular and infection microbiology 2021;11:647220
Frontiers in cellular and infection microbiology 2021;11:647220
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.
Liu Q, Zheng B, Zhang Y, Huang W, Hong Q, Meng Y
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Canadian journal of physiology and pharmacology 2021 Sep;99(9):885-893
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Yang Y, Tian J, Zhang H, Ma M, Li H, Liu T, Yang Y, Liu T, She R
Virus research 2021 Sep;302:198369
Virus research 2021 Sep;302:198369
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
Davis SE, Roth JR, Aljabi Q, Hakim AR, Savell KE, Day JJ, Arrant AE
The Journal of biological chemistry 2021 Sep;297(3):100993
The Journal of biological chemistry 2021 Sep;297(3):100993
Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
Meng L, Goto M, Tanaka H, Kamikokura Y, Fujii Y, Okada Y, Furukawa H, Nishikawa Y
The American journal of pathology 2021 Sep;191(9):1580-1591
The American journal of pathology 2021 Sep;191(9):1580-1591
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Wang C, Qu L, Li S, Yin F, Ji L, Peng W, Luo H, Lu D, Liu X, Chen X, Kong L, Wang X
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model.
Wu C, Zhao J, Wu Q, Tan Q, Liu Q, Xiao S
International journal of molecular sciences 2021 Sep 8;22(18)
International journal of molecular sciences 2021 Sep 8;22(18)
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X
Nature communications 2021 Sep 6;12(1):5305
Nature communications 2021 Sep 6;12(1):5305
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
Chronic Restraint Stress-Induced Muscle Atrophy Leads to Fatigue in Mice by Inhibiting the AMPK Signaling Pathway.
Wang Z, Xia T, Jin S, Liu X, Pan R, Yan M, Chang Q
Biomedicines 2021 Sep 26;9(10)
Biomedicines 2021 Sep 26;9(10)
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
Lu H, Jia C, Wu D, Jin H, Lin Z, Pan J, Li X, Wang W
Cell death & disease 2021 Sep 23;12(10):865
Cell death & disease 2021 Sep 23;12(10):865
7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease.
Zuo L, Dai C, Yi L, Dong Z
Cell death discovery 2021 Sep 20;7(1):254
Cell death discovery 2021 Sep 20;7(1):254
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
Fasting improves tolerance to acute hypoxia in rats.
Yue XY, Wang XB, Zhao RZ, Jiang S, Zhou X, Jiao B, Zhang L, Yu ZB
Biochemical and biophysical research communications 2021 Sep 10;569:161-166
Biochemical and biophysical research communications 2021 Sep 10;569:161-166
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Wu Z, Zhang Y, Liu Y, Chen X, Huang Z, Zhao X, He H, Deng Y
Life (Basel, Switzerland) 2021 Sep 10;11(9)
Life (Basel, Switzerland) 2021 Sep 10;11(9)
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
Kang M, Luo J, Zhao L, Shi F, Ye G, He X, Hao S, Yang D, Chen H, Guo H, Li Y, Tang H
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
l-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration.
Zhang S, Zhou H, Kong N, Wang Z, Fu H, Zhang Y, Xiao Y, Yang W, Yan F
Bioactive materials 2021 Oct;6(10):3288-3299
Bioactive materials 2021 Oct;6(10):3288-3299
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Deng YJ, Lin XP, Li XQ, Lu PF, Cai Y, Liu LL, Pei GC, Han M
Current medical science 2021 Oct;41(5):880-887
Current medical science 2021 Oct;41(5):880-887
Bergenin attenuates bleomycin-induced pulmonary fibrosis in mice via inhibiting TGF-β1 signaling pathway.
Li X, Wang Y, Liang J, Bi Z, Ruan H, Cui Y, Ma L, Wei Y, Zhou B, Zhang L, Zhou H, Yang C
Phytotherapy research : PTR 2021 Oct;35(10):5808-5822
Phytotherapy research : PTR 2021 Oct;35(10):5808-5822
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy.
Liu T, Wang L, Liang P, Wang X, Liu Y, Cai J, She Y, Wang D, Wang Z, Guo Z, Bates S, Xia X, Huang J, Cui J
Cellular & molecular immunology 2021 Oct;18(10):2431-2442
Cellular & molecular immunology 2021 Oct;18(10):2431-2442
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Tang Y, Liu J, Wang Y, Yang L, Han B, Zhang Y, Bai Y, Shen L, Li M, Jiang T, Ye Q, Yu X, Huang R, Zhang Z, Xu Y, Yao H
Autophagy 2021 Oct;17(10):2905-2922
Autophagy 2021 Oct;17(10):2905-2922
Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.
Wang B, Cao C, Han D, Bai J, Guo J, Guo Q, Li D, Zhang J, Zhang Z, Wang Y, Tang J, Shen D, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112056
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112056
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Li X, Liu S, Chen X, Huang R, Ma L, Weng H, Yu Y, Zong X
NPJ breast cancer 2021 Oct 7;7(1):132
NPJ breast cancer 2021 Oct 7;7(1):132
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Co-modification with MSC membrane and PDA prevents Fe(3)O(4)-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154
Toxicology letters 2021 Oct 15;351:145-154
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Duan J, Chen H, Li Y, Xu D, Li X, Zhang Z, Cheng J, Yang L, Li Q
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11847-11855
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Kong L, Deng J, Zhou X, Cai B, Zhang B, Chen X, Chen Z, Wang W
Cell death & disease 2021 Oct 11;12(10):928
Cell death & disease 2021 Oct 11;12(10):928
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
Li N, Yan M, Chen Y, Wang Y, Wu J, Fu L, Yu J
Experimental cell research 2021 Oct 1;407(1):112780
Experimental cell research 2021 Oct 1;407(1):112780
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle.
Mori T, Ato S, Knudsen JR, Henriquez-Olguin C, Li Z, Wakabayashi K, Suginohara T, Higashida K, Tamura Y, Nakazato K, Jensen TE, Ogasawara R
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E551-E559
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E551-E559
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.
Xu K, Lu C, Ren X, Wang J, Xu P, Zhang Y
Environmental toxicology 2021 Nov;36(11):2123-2137
Environmental toxicology 2021 Nov;36(11):2123-2137
eIF2A-knockout mice reveal decreased life span and metabolic syndrome.
Anderson R, Agarwal A, Ghosh A, Guan BJ, Casteel J, Dvorina N, Baldwin WM 3rd, Mazumder B, Nazarko TY, Merrick WC, Buchner DA, Hatzoglou M, Kondratov RV, Komar AA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21990
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21990
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E(2) Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride.
Chen Q, Li Z, Xu Z, Chen C, Wang J, Zhu J, Dong Z
Biological trace element research 2021 Nov;199(11):4119-4128
Biological trace element research 2021 Nov;199(11):4119-4128
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Yang X, Jin N, Wang Y, Yao Y, Wang Y, Li T, Liu C, Yu T, Yin H, Zhang Z, Cheng SY, Yue S
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.
Zhang M, Yan W, Yu Y, Cheng J, Yi X, Guo T, Liu N, Shang J, Wang Z, Hu H, Chen L
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Journal of pharmacological sciences 2021 Nov;147(3):234-244
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J
Research in veterinary science 2021 Nov;140:18-25
Research in veterinary science 2021 Nov;140:18-25
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
Li R, Yao G, Zhou L, Zhang M, Yan J, Wang X, Li Y
Microvascular research 2021 Nov;138:104230
Microvascular research 2021 Nov;138:104230
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Guo X, Bao X, Wang X, Liu D, Liu P, Chi T, Ji X, Zheng Z, Chen G, Zou L
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Li M, Cheng W, Zhang L
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Xi H, Ren F, Li Y, Du Y, Wang L, Hu J
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
Duan J, Chen H, Xu D, Li Y, Li X, Cheng J, Hua R, Zhang Z, Yang L, Li Q
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
Acetylation of STX17 (syntaxin 17) controls autophagosome maturation.
Shen Q, Shi Y, Liu J, Su H, Huang J, Zhang Y, Peng C, Zhou T, Sun Q, Wan W, Liu W
Autophagy 2021 May;17(5):1157-1169
Autophagy 2021 May;17(5):1157-1169
Biosynthetic gold nanoparticles of Hibiscus syriacus L. callus potentiates anti-inflammation efficacy via an autophagy-dependent mechanism.
Xu XY, Tran THM, Perumalsamy H, Sanjeevram D, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
Materials science & engineering. C, Materials for biological applications 2021 May;124:112035
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
Liu X, Wang Q, Shao Z, Zhang S, Hou M, Jiang M, Du M, Li J, Yuan H
Human molecular genetics 2021 May 31;30(11):1030-1044
Human molecular genetics 2021 May 31;30(11):1030-1044
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
Yang A, Wang L, Jiang K, Lei L, Li H
Biochemical and biophysical research communications 2021 May 21;554:123-130
Biochemical and biophysical research communications 2021 May 21;554:123-130
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Martin TG, Myers VD, Dubey P, Dubey S, Perez E, Moravec CS, Willis MS, Feldman AM, Kirk JA
Nature communications 2021 May 19;12(1):2942
Nature communications 2021 May 19;12(1):2942
Interfering with hyaluronic acid metabolism suppresses glioma cell proliferation by regulating autophagy.
Yan T, Chen X, Zhan H, Yao P, Wang N, Yang H, Zhang C, Wang K, Hu H, Li J, Sun J, Dong Y, Lu E, Zheng Z, Zhang R, Wang X, Ma J, Gao M, Ye J, Wang X, Teng L, Liu H, Zhao S
Cell death & disease 2021 May 13;12(5):486
Cell death & disease 2021 May 13;12(5):486
Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection.
Gestuveo RJ, Royle J, Donald CL, Lamont DJ, Hutchinson EC, Merits A, Kohl A, Varjak M
Nature communications 2021 May 13;12(1):2766
Nature communications 2021 May 13;12(1):2766
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Lactobacillus salivarius ameliorated Mycoplasma gallisepticum-induced inflammatory injury and secondary Escherichia coli infection in chickens: Involvement of intestinal microbiota.
Wang J, Ishfaq M, Li J
Veterinary immunology and immunopathology 2021 Mar;233:110192
Veterinary immunology and immunopathology 2021 Mar;233:110192
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
Hou J, Zhao L, Tang H, He X, Ye G, Shi F, Kang M, Chen H, Li Y
Biological trace element research 2021 Mar;199(3):1062-1073
Biological trace element research 2021 Mar;199(3):1062-1073
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts.
Ma L, Liu H, Wang X, Jiang C, Yao S, Guo Y, Wang H, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Mar;1868(3):118923
Biochimica et biophysica acta. Molecular cell research 2021 Mar;1868(3):118923
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X, Zhang H, Meng L, Song H, Zhou Q, Qu C, Zhao P, Li Q, Zou C, Liu X, Zhang Z
Autophagy 2021 Mar;17(3):723-742
Autophagy 2021 Mar;17(3):723-742
Hongjingtian injection protects against myocardial ischemia reperfusion-induced apoptosis by blocking ROS induced autophagic- flux.
Zhao J, Zhang J, Liu Q, Wang Y, Jin Y, Yang Y, Ni C, Zhang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111205
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111205
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b.
Li J, Yang T, Sha Z, Tang H, Hua X, Wang L, Wang Z, Gao Z, Sluijter JPG, Rowe GC, Das S, Yang L, Xiao J
Molecular therapy. Nucleic acids 2021 Mar 5;23:743-756
Molecular therapy. Nucleic acids 2021 Mar 5;23:743-756
Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions.
Li J, Yang T, Tang H, Sha Z, Chen R, Chen L, Yu Y, Rowe GC, Das S, Xiao J
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1102-1119
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1102-1119
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Li HG, Tian WH, Qin CL, Ye RR, Liu DH, Liu HW
Aging 2021 Mar 19;13(7):9704-9718
Aging 2021 Mar 19;13(7):9704-9718
The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Zhang S, Shao Z, Liu X, Hou M, Cheng F, Lei D, Yuan H
Cell death discovery 2021 Mar 15;7(1):49
Cell death discovery 2021 Mar 15;7(1):49
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Li X, Sun L, Yan G, Yan X
Cellular signalling 2021 Jun;82:109956
Cellular signalling 2021 Jun;82:109956
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Guo W, Zhao Y, Li H, Lei L
Journal of periodontal research 2021 Jun;56(3):523-534
Journal of periodontal research 2021 Jun;56(3):523-534
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Chen L, Mei G, Jiang C, Cheng X, Li D, Zhao Y, Chen H, Wan C, Yao P, Gao C, Tang Y
Cell proliferation 2021 Jun;54(6):e13052
Cell proliferation 2021 Jun;54(6):e13052
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, Shi W, Chen Y, Liu J, Qu Z, Li S, Xie X, Li M
Cell proliferation 2021 Jun;54(6):e13048
Cell proliferation 2021 Jun;54(6):e13048
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Zhang X, Wei M, Fan J, Yan W, Zha X, Song H, Wan R, Yin Y, Wang W
Autophagy 2021 Jun;17(6):1519-1542
Autophagy 2021 Jun;17(6):1519-1542
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Ruan C, Wang C, Gong X, Zhang Y, Deng W, Zhou J, Huang D, Wang Z, Zhang Q, Guo A, Lu J, Gao J, Peng D, Xue Y
Autophagy 2021 Jun;17(6):1426-1447
Autophagy 2021 Jun;17(6):1426-1447
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
Zhang M, Zhang T, Song C, Qu J, Gu Y, Liu S, Li H, Xiao W, Kong L, Sun Y, Lv W
Journal of ethnopharmacology 2021 Jun 28;274:114064
Journal of ethnopharmacology 2021 Jun 28;274:114064
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice.
Li H, Qin S, Liang Q, Xi Y, Bo W, Cai M, Tian Z
Biomedicines 2021 Jun 21;9(6)
Biomedicines 2021 Jun 21;9(6)
Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
Amegandjin CA, Choudhury M, Jadhav V, Carriço JN, Quintal A, Berryer M, Snapyan M, Chattopadhyaya B, Saghatelyan A, Di Cristo G
Nature communications 2021 Jun 16;12(1):3653
Nature communications 2021 Jun 16;12(1):3653
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Wang W, Qin Y, Song H, Wang L, Jia M, Zhao C, Gong M, Zhao W
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Zhu F, Li X, Tang X, Jiang J, Han Y, Li Y, Ma C, Liu Z, He Y
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Autophagy inhibition and microRNA‑199a‑5p upregulation in paclitaxel‑resistant A549/T lung cancer cells.
Zeng T, Xu M, Zhang W, Gu X, Zhao F, Liu X, Zhang X
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
Zhang Q, Feng Z, Lu J, Lu J, Guan S, Chen Y
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
Jia X, Zhang A, Li Z, Peng X, Tian X, Gao F
Journal of neurochemistry 2021 Jul;158(2):373-390
Journal of neurochemistry 2021 Jul;158(2):373-390
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Ferreira N, Gram H, Sorrentino ZA, Gregersen E, Schmidt SI, Reimer L, Betzer C, Perez-Gozalbo C, Beltoja M, Nagaraj M, Wang J, Nowak JS, Dong M, Willén K, Cholak E, Bjerregaard-Andersen K, Mendez N, Rabadia P, Shahnawaz M, Soto C, Otzen DE, Akbey Ü, Meyer M, Giasson BI, Romero-Ramos M, Jensen PH
Acta neuropathologica 2021 Jul;142(1):87-115
Acta neuropathologica 2021 Jul;142(1):87-115
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Zhang X, Lv S, Zhang W, Jia Q, Wang L, Ding Y, Yuan P, Zhu Y, Liu L, Li Y, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
The Difference in Expression of Autophagy-Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo-A Cross-Sectional Pilot Study.
Yu H, Lin X, Huang Y, Cheng H, Seifert O
Indian journal of dermatology 2021 Jul-Aug;66(4):331-336
Indian journal of dermatology 2021 Jul-Aug;66(4):331-336
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
Activated autophagy restored the impaired frequency and function of regulatory T cells in chronic prostatitis.
Liu Y, Zhang Y, Zhang M, Meng J, Ma Q, Hao Z, Zheng M, Zhang L, Chen X, Liang C
The Prostate 2021 Jan;81(1):29-40
The Prostate 2021 Jan;81(1):29-40
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury.
Wang Y, Zhu J, Liu Z, Shu S, Fu Y, Liu Y, Cai J, Tang C, Liu Y, Yin X, Dong Z
Redox biology 2021 Jan;38:101767
Redox biology 2021 Jan;38:101767
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Wang J, Zhu H, Lin S, Wang K, Wang H, Liu Z
Journal of inorganic biochemistry 2021 Jan;214:111310
Journal of inorganic biochemistry 2021 Jan;214:111310
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Han F, Guo H, Wang L, Zhang Y, Sun L, Dai C, Wu X
Experimental eye research 2021 Jan;202:108366
Experimental eye research 2021 Jan;202:108366
Srag Regulates Autophagy via Integrating into a Preexisting Autophagy Pathway in Testis.
Cheng Y, Lai F, Wang X, Shang D, Zou J, Luo M, Xia X, Cheng H, Zhou R
Molecular biology and evolution 2021 Jan 4;38(1):128-141
Molecular biology and evolution 2021 Jan 4;38(1):128-141
Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.
Jin P, Li LH, Shi Y, Hu NB
Gene 2021 Jan 30;767:145075
Gene 2021 Jan 30;767:145075
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Zhou Y, Yan M, Pan R, Wang Z, Tao X, Li C, Xia T, Liu X, Chang Q
Journal of ethnopharmacology 2021 Jan 30;265:113317
Journal of ethnopharmacology 2021 Jan 30;265:113317
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Feng S, Qiu G, Yang L, Feng L, Fan X, Ren F, Huang K, Chen Y
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Zong DD, Liu XM, Li JH, Ouyang RY, Long YJ, Chen P, Chen Y
Respiratory research 2021 Jan 19;22(1):22
Respiratory research 2021 Jan 19;22(1):22
Atmospheric PM(2.5) blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
Liu Y, Zhao D, Peng W, Xue P, Jiang X, Chen S, Gao H, Wang X, Feng S
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Xu C, Cao H, Sui Y, Zhang H, Shi C, Wu J, Ma R, Feng J
Cancer cell international 2021 Jan 12;21(1):48
Cancer cell international 2021 Jan 12;21(1):48
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
Qin S, Ye L, Zheng Y, Gao J
FEBS letters 2021 Feb;595(4):507-520
FEBS letters 2021 Feb;595(4):507-520
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome.
Rahim I, Sayed RK, Fernández-Ortiz M, Aranda-Martínez P, Guerra-Librero A, Fernández-Martínez J, Rusanova I, Escames G, Djerdjouri B, Acuña-Castroviejo D
Naunyn-Schmiedeberg's archives of pharmacology 2021 Feb;394(2):261-277
Naunyn-Schmiedeberg's archives of pharmacology 2021 Feb;394(2):261-277
Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.
Yuan W, He X, Morin D, Barrière G, Liu X, Li J, Zhu Y
Journal of neurotrauma 2021 Feb;38(3):373-384
Journal of neurotrauma 2021 Feb;38(3):373-384
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
Liu Y, Wang Y, Liu J, Kang R, Tang D
Cancer gene therapy 2021 Feb;28(1-2):55-63
Cancer gene therapy 2021 Feb;28(1-2):55-63
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells.
Zhao Y, Wang W, Pan W, Yu Y, Huang W, Gao J, Zhang Y, Zhang S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J
Biological trace element research 2021 Feb;199(2):703-711
Biological trace element research 2021 Feb;199(2):703-711
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Wang R, Zhu Y, Ren C, Yang S, Tian S, Chen H, Jin M, Zhou H
Autophagy 2021 Feb;17(2):496-511
Autophagy 2021 Feb;17(2):496-511
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Zhou K, Xu Y, Wang Q, Dong L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Deng Z, Sun M, Wu J, Fang H, Cai S, An S, Huang Q, Chen Z, Wu C, Zhou Z, Hu H, Zeng Z
Cell death & disease 2021 Feb 26;12(2):217
Cell death & disease 2021 Feb 26;12(2):217
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Zhang MH, Li J, Zhu XY, Zhang YQ, Ye ST, Leng YR, Yang T, Zhang H, Kong LY
Free radical biology & medicine 2021 Feb 20;164:1-12
Free radical biology & medicine 2021 Feb 20;164:1-12
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway.
Li X, Ma L, Huang K, Wei Y, Long S, Liu Q, Zhang D, Wu S, Wang W, Yang G, Zhou H, Yang C
International journal of molecular sciences 2021 Feb 17;22(4)
International journal of molecular sciences 2021 Feb 17;22(4)
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
Lu Q, Gu W, Luo C, Wang L, Hua W, Sun Y, Tang L
Journal of ethnopharmacology 2021 Feb 10;266:113454
Journal of ethnopharmacology 2021 Feb 10;266:113454
ZFP91 is required for the maintenance of regulatory T cell homeostasis and function.
Wang A, Ding L, Wu Z, Ding R, Teng XL, Wang F, Hu Z, Chen L, Yu X, Zou Q
The Journal of experimental medicine 2021 Feb 1;218(2)
The Journal of experimental medicine 2021 Feb 1;218(2)
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
Yu YG, Han JH, Xue HX, Li WZ, Wu WN, Yin YY
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
The abrupt pathological deterioration of cisplatin-induced acute kidney injury: Emerging of a critical time point.
Gong Q, Wang M, Jiang Y, Zha C, Yu D, Lei F, Luo Y, Feng Y, Yang S, Li J, Du L
Pharmacology research & perspectives 2021 Dec;9(6):e00895
Pharmacology research & perspectives 2021 Dec;9(6):e00895
Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs).
Lin Y, Chen T, Chen J, Fang Y, Zeng C
Annals of translational medicine 2021 Dec;9(24):1794
Annals of translational medicine 2021 Dec;9(24):1794
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy.
Wang X, Wu F, Deng Y, Chai J, Zhang Y, He G, Li X
International journal of oncology 2021 Dec;59(6)
International journal of oncology 2021 Dec;59(6)
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
Okubo K, REßING N, Schulz WA, Hansen FK, Asano T, Sato A
Anticancer research 2021 Dec;41(12):5987-5996
Anticancer research 2021 Dec;41(12):5987-5996
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.
Huang H, Ding R, Chen Z, Yi Z, Wang H, Lv Y, Bao E
Veterinary microbiology 2021 Dec;263:109244
Veterinary microbiology 2021 Dec;263:109244
Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.
Meng Q, Zaharieva EK, Sasatani M, Kobayashi J
Redox report : communications in free radical research 2021 Dec;26(1):160-169
Redox report : communications in free radical research 2021 Dec;26(1):160-169
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G(1)/S cycle.
Lei Y, Xu X, Liu H, Chen L, Zhou H, Jiang J, Yang Y, Wu B
Autophagy 2021 Dec;17(12):4423-4441
Autophagy 2021 Dec;17(12):4423-4441
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Zhong S, Lian Y, Luo W, Luo R, Wu X, Ji J, Ji Y, Ding J, Wang X
Acta neuropathologica 2021 Dec;142(6):1003-1023
Acta neuropathologica 2021 Dec;142(6):1003-1023
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Wang B, Ji D, Xing W, Li F, Huang Z, Zheng W, Xue J, Zhu Y, Yang X
Cartilage 2021 Dec;13(2_suppl):592S-603S
Cartilage 2021 Dec;13(2_suppl):592S-603S
Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells.
Duan JX, Guan XX, Yang HH, Mei WX, Chen P, Tao JH, Li Q, Zhou Y
International immunopharmacology 2021 Dec;101(Pt B):108211
International immunopharmacology 2021 Dec;101(Pt B):108211
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
Su WQ, Yu XJ, Zhou CM
Viruses 2021 Dec 9;13(12)
Viruses 2021 Dec 9;13(12)
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis.
Yi J, Wu S, Tan S, Qin Y, Wang X, Jiang J, Liu H, Wu B
Cell death discovery 2021 Dec 4;7(1):374
Cell death discovery 2021 Dec 4;7(1):374
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
Wang G, Qin S, Zheng Y, Xia C, Zhang P, Zhang L, Yao J, Yi Y, Deng L
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Chen J, Mao K, Yu H, Wen Y, She H, Zhang H, Liu L, Li M, Li W, Zou F
Journal of neuroinflammation 2021 Dec 20;18(1):295
Journal of neuroinflammation 2021 Dec 20;18(1):295
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Feng X, Jiang T, Yang C, Pang S, Ding Z, Hu H, Wang H, Dong L, Yang N
Cell death & disease 2021 Dec 17;13(1):6
Cell death & disease 2021 Dec 17;13(1):6
LncRNA RP11-295G20.2 regulates hepatocellular carcinoma cell growth and autophagy by targeting PTEN to lysosomal degradation.
Liang L, Huan L, Wang J, Wu Y, Huang S, He X
Cell discovery 2021 Dec 14;7(1):118
Cell discovery 2021 Dec 14;7(1):118
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
Pulmonary Exposure to Copper Oxide Nanoparticles Leads to Neurotoxicity via Oxidative Damage and Mitochondrial Dysfunction.
Zhou H, Yao L, Jiang X, Sumayyah G, Tu B, Cheng S, Qin X, Zhang J, Zou Z, Chen C
Neurotoxicity research 2021 Aug;39(4):1160-1170
Neurotoxicity research 2021 Aug;39(4):1160-1170
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Wu W, Dong J, Gou H, Geng R, Yang X, Chen D, Xiang B, Zhang Z, Ren S, Chen L, Liu J
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Liu J, Liu L, Han YS, Yi J, Guo C, Zhao HQ, Ling J, Wang YH
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Zhang L, Zou L, Jiang X, Cheng S, Zhang J, Qin X, Qin Z, Chen C, Zou Z
Nanotoxicology 2021 Aug;15(6):779-797
Nanotoxicology 2021 Aug;15(6):779-797
Biosynthesis of gold nanoparticles using Nigella sativa and Curtobacterium proimmune K3 and evaluation of their anticancer activity.
Dhandapani S, Xu X, Wang R, Puja AM, Kim H, Perumalsamy H, Balusamy SR, Kim YJ
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112214
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Wu C, Zhou XX, Li JZ, Qiang HF, Wang Y, Li G
Stem cell research & therapy 2021 Aug 5;12(1):437
Stem cell research & therapy 2021 Aug 5;12(1):437
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes.
Dybas JM, Lum KK, Kulej K, Reyes ED, Lauman R, Charman M, Purman CE, Steinbock RT, Grams N, Price AM, Mendoza L, Garcia BA, Weitzman MD
mSystems 2021 Aug 31;6(4):101128msystems0046821
mSystems 2021 Aug 31;6(4):101128msystems0046821
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Zhao Y, Lu J, Mao A, Zhang R, Guan S
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47
Free radical biology & medicine 2021 Aug 20;172:33-47
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Yan M, Wang Z, Xia T, Jin S, Liu Y, Hu H, Chang Q
Biomedicines 2021 Aug 2;9(8)
Biomedicines 2021 Aug 2;9(8)
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis.
Yang RZ, Xu WN, Zheng HL, Zheng XF, Li B, Jiang LS, Jiang SD
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Journal of cellular physiology 2021 Apr;236(4):2725-2739
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Nie L, Liu M, Chen J, Wu Q, Li Y, Yi J, Zheng X, Zhang J, Chu C, Yang J
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Yang B, Zang J, Yuan W, Jiang X, Zhang F
Experimental and therapeutic medicine 2021 Apr;21(4):317
Experimental and therapeutic medicine 2021 Apr;21(4):317
UBXN7 cofactor of CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins.
Di Gregorio J, Cilenti L, Ambivero CT, Andl T, Liao R, Zervos AS
Biochimica et biophysica acta. Molecular cell research 2021 Apr;1868(4):118963
Biochimica et biophysica acta. Molecular cell research 2021 Apr;1868(4):118963
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Kong XT, Wang Z, Mou JJ, Li CS, Xue HL, Wu M, Chen L, Xu JH, Xu LX
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
Liu S, Jiang X, Cui X, Wang J, Liu S, Li H, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Apr 9;12(4):385
Cell death & disease 2021 Apr 9;12(4):385
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Lu J, Fan Y, Liu M, Zhang Q, Guan S
Toxicology 2021 Apr 30;454:152716
Toxicology 2021 Apr 30;454:152716
PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells.
Mao L, Liu H, Zhang R, Deng Y, Hao Y, Liao W, Yuan M, Sun S
Aging 2021 Apr 30;13(9):12955-12972
Aging 2021 Apr 30;13(9):12955-12972
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Liu A, Wang W, Lu Z, Liu Z, Zhou W, Zhong Z, Ye Q
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats.
Zhang W, Huang B, Gao L, Huang C
International journal of molecular sciences 2021 Apr 21;22(9)
International journal of molecular sciences 2021 Apr 21;22(9)
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Zhang M, Wu P, Li M, Guo Y, Tian T, Liao X, Tan S
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Biochemical and biophysical research communications 2021 Apr 2;547:131-138
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Xiao W, Yeerken D, Li J, Li Z, Jiang L, Li D, Fu M, Ma L, Song Y, Zhang W, Zhan Q
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
LC3B/p62-mediated mitophagy protects A549 cells from resveratrol-induced apoptosis.
Zheng J, Wei S, Xiao T, Li G
Life sciences 2021 Apr 15;271:119139
Life sciences 2021 Apr 15;271:119139
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hu J, Ding X, Tian S, Chu Y, Liu Z, Li Y, Li X, Wang G, Wang L, Wang Z
Cell death & disease 2021 Apr 12;12(4):391
Cell death & disease 2021 Apr 12;12(4):391
Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis.
Chen S, Ma J, Yang L, Teng M, Lai ZQ, Chen X, He J
Frontiers in bioengineering and biotechnology 2020;8:614419
Frontiers in bioengineering and biotechnology 2020;8:614419
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Du J, Dong Z, Tan L, Tan M, Zhang F, Zhang K, Pan G, Li C, Shi S, Zhang Y, Liu Y, Cui H
Frontiers in cell and developmental biology 2020;8:607757
Frontiers in cell and developmental biology 2020;8:607757
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Zhang W, Hou W, Chen M, Chen E, Xue D, Ye C, Li W, Pan Z
Frontiers in cell and developmental biology 2020;8:576104
Frontiers in cell and developmental biology 2020;8:576104
NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial-Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production.
Xu WN, Yang RZ, Zheng HL, Jiang LS, Jiang SD
Frontiers in cell and developmental biology 2020;8:515051
Frontiers in cell and developmental biology 2020;8:515051
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Zhang Z, Han K, Wang C, Sun C, Jia N
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
Xu YL, Liu XY, Cheng SB, He PK, Hong MK, Chen YY, Zhou FH, Jia YH
The American journal of Chinese medicine 2020;48(8):1821-1840
The American journal of Chinese medicine 2020;48(8):1821-1840
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Chen YL, Yen IC, Lin KT, Lai FY, Lee SY
The American journal of Chinese medicine 2020;48(5):1243-1261
The American journal of Chinese medicine 2020;48(5):1243-1261
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Huang Y, Liao Y, Zhang H, Li S
The Journal of toxicological sciences 2020;45(9):559-567
The Journal of toxicological sciences 2020;45(9):559-567
Yi-Zhi-Fang-Dai Formula Exerts a Protective Effect on the Injury of Tight Junction Scaffold Proteins in Vitro and in Vivo by Mediating Autophagy through Regulation of the RAGE/CaMKKβ/AMPK/mTOR Pathway.
Chan Y, Chen W, Chen Y, Lv Z, Wan W, Li Y, Zhang C
Biological & pharmaceutical bulletin 2020;43(12):1847-1858
Biological & pharmaceutical bulletin 2020;43(12):1847-1858
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Li QW, Yang Q, Liu HY, Wu YL, Hao YH, Zhang XQ
BioMed research international 2020;2020:7598375
BioMed research international 2020;2020:7598375
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Feng TY, Li Q, Ren F, Xi HM, Lv DL, Li Y, Hu JH
Oxidative medicine and cellular longevity 2020;2020:5954635
Oxidative medicine and cellular longevity 2020;2020:5954635
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Kuang M, Yang M, Li L, Li C, Wang G
Oxidative medicine and cellular longevity 2020;2020:4045674
Oxidative medicine and cellular longevity 2020;2020:4045674
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis.
Cheng Y, Pan X, Wang J, Li X, Yang S, Yin R, Ma A, Zhu X
Oxidative medicine and cellular longevity 2020;2020:3186306
Oxidative medicine and cellular longevity 2020;2020:3186306
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway.
Zhao X, Liu L, Jiang Y, Silva M, Zhen X, Zheng W
Oxidative medicine and cellular longevity 2020;2020:2524174
Oxidative medicine and cellular longevity 2020;2020:2524174
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy.
Williams T, Sorrentino Z, Weinrich M, Giasson BI, Chakrabarty P
Brain communications 2020;2(2):fcaa090
Brain communications 2020;2(2):fcaa090
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
RAB37 multiple alleles, transcription activation and evolution in mammals.
Xu X, Hu M, Ying R, Zou J, Lin L, Cheng H, Zhou R
International journal of biological sciences 2020;16(15):2964-2973
International journal of biological sciences 2020;16(15):2964-2973
IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation.
Xu L, Wang J, Yuan X, Yang S, Xu X, Li K, He Y, Wei L, Zhang J, Tian Y
International journal of biological sciences 2020;16(15):2951-2963
International journal of biological sciences 2020;16(15):2951-2963
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition.
Cai Q, Wang X, Wang S, Jin L, Ding J, Zhou D, Ma F
International journal of nanomedicine 2020;15:253-262
International journal of nanomedicine 2020;15:253-262
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Zhang Y, Huang N, Xu J, Zheng W, Cui X
Drug design, development and therapy 2020;14:4749-4763
Drug design, development and therapy 2020;14:4749-4763
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
You G, Long X, Song F, Huang J, Tian M, Xiao Y, Deng S, Wu Q
Drug design, development and therapy 2020;14:457-468
Drug design, development and therapy 2020;14:457-468
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Li Z, Cheng J, Liu J
Drug design, development and therapy 2020;14:2645-2655
Drug design, development and therapy 2020;14:2645-2655
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Wang MM, Zhang M, Feng YS, Xing Y, Tan ZX, Li WB, Dong F, Zhang F
Frontiers in cellular neuroscience 2020;14:134
Frontiers in cellular neuroscience 2020;14:134
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Xu X, Chen B, Huang Q, Wu Y, Liang T
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
Zhang T, Wang H, Lu M, Zhao K, Yin J, Liu Y, Sun Y
American journal of translational research 2020;12(9):5332-5342
American journal of translational research 2020;12(9):5332-5342
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
Zuo H, Chen C, Ma L, Min QX, Shen YH
American journal of translational research 2020;12(10):6478-6489
American journal of translational research 2020;12(10):6478-6489
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy.
Li W, Qin X, Wang B, Xu G, Zhang J, Jiang X, Chen C, Qiu F, Zou Z
Cancer management and research 2020;12:6563-6573
Cancer management and research 2020;12:6563-6573
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Wang C, Shi Z, Hong Z, Pan J, Chen Z, Qiu C, Zhuang H, Zheng X
Cancer management and research 2020;12:12185-12195
Cancer management and research 2020;12:12185-12195
Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.
Zhang W, Zhang S, Guan W, Huang Z, Kong J, Huang C, Wang H, Yang S
Frontiers in genetics 2020;11:930
Frontiers in genetics 2020;11:930
Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.
Wen X, Liu L, Li S, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
Frontiers in physiology 2020;11:868
Frontiers in physiology 2020;11:868
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju L, Zhuang X, Jiang X
Frontiers in pharmacology 2020;11:84
Frontiers in pharmacology 2020;11:84
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Zheng Y, Zhu G, Tang Y, Yan J, Han S, Yin J, Peng B, He X, Liu W
Frontiers in microbiology 2020;11:78
Frontiers in microbiology 2020;11:78
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Wang N, Muhetaer G, Zhang X, Yang B, Wang C, Zhang Y, Wang X, Zhang J, Wang S, Zheng Y, Zhang F, Wang Z
Frontiers in pharmacology 2020;11:591400
Frontiers in pharmacology 2020;11:591400
Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux.
He X, Yuan W, Liu F, Feng J, Guo Y
Frontiers in pharmacology 2020;11:586302
Frontiers in pharmacology 2020;11:586302
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly.
Ding W, Ding Z, Wang Y, Zhu Y, Gao Q, Cao W, Du R
Frontiers in pharmacology 2020;11:573870
Frontiers in pharmacology 2020;11:573870
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Wang Z, Xu JH, Mou JJ, Kong XT, Wu M, Xue HL, Xu LX
Frontiers in physiology 2020;11:408
Frontiers in physiology 2020;11:408
The Effect of Autophagy on Chronic Intermittent Hypobaric Hypoxia Ameliorating Liver Damage in Metabolic Syndrome Rats.
Cui F, Hu HF, Guo J, Sun J, Shi M
Frontiers in physiology 2020;11:13
Frontiers in physiology 2020;11:13
NLRC5 Inhibits Inflammation of Secretory Phase Ectopic Endometrial Stromal Cells by Up-Regulating Autophagy in Ovarian Endometriosis.
He R, Liu X, Zhang J, Wang Z, Wang W, Fu L, Fan Y, Sun S, Cao Y, Zhan L, Shui L
Frontiers in pharmacology 2020;11:1281
Frontiers in pharmacology 2020;11:1281
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Zhou B, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N, Wu Z
Frontiers in oncology 2020;10:606790
Frontiers in oncology 2020;10:606790
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Li P, Cao G, Huang Y, Wu W, Chen B, Wang Z, Xiong M
Frontiers in oncology 2020;10:541262
Frontiers in oncology 2020;10:541262
Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy.
Wu C, Yang M, Liu R, Hu H, Ji L, Zhang X, Huang S, Wang L
Frontiers in cellular and infection microbiology 2020;10:484
Frontiers in cellular and infection microbiology 2020;10:484
PIWI-Interacting RNA-004800 Is Regulated by S1P Receptor Signaling Pathway to Keep Myeloma Cell Survival.
Ma H, Wang H, Tian F, Zhong Y, Liu Z, Liao A
Frontiers in oncology 2020;10:438
Frontiers in oncology 2020;10:438
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Xu LY, Mu M, Wang ML, Liu JC, Zhou YJ, Wu J, Jiang BY, Chen MG, Hu D, Tao XR
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
Zhao L, Kong X, Zhong W, Wang Y, Li P
Pathology, research and practice 2020 Sep;216(9):153042
Pathology, research and practice 2020 Sep;216(9):153042
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Yang F, Qu Q, Zhao C, Liu X, Yang P, Li Z, Han L, Shi X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo.
Bressan C, Pecora A, Gagnon D, Snapyan M, Labrecque S, De Koninck P, Parent M, Saghatelyan A
eLife 2020 Sep 28;9
eLife 2020 Sep 28;9
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Wu CH, Ou CH, Yen IC, Lee SY
International journal of molecular sciences 2020 Sep 22;21(18)
International journal of molecular sciences 2020 Sep 22;21(18)
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Ye X, Xie G, Liu Z, Tang J, Cui M, Wang C, Guo C, Tang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Liu Z, Lv X, Xu L, Liu X, Zhu X, Song E, Song Y
Particle and fibre toxicology 2020 Sep 18;17(1):46
Particle and fibre toxicology 2020 Sep 18;17(1):46
Inhibition of Endoplasmic Reticulum Stress-Mediated Autophagy Enhances the Anticancer Effect of Iodine-125 Seed Radiation on Esophageal Squamous Cell Carcinoma.
Wang C, Li TK, Zeng CH, Yang J, Wang Y, Lu J, Zhu GY, Guo JH
Radiation research 2020 Sep 16;194(3):236-245
Radiation research 2020 Sep 16;194(3):236-245
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Qu W, Tarique I, Deng B, Zhang Y, Haseeb A, Chen Q, Yang P
Theriogenology 2020 Sep 15;154:237-245
Theriogenology 2020 Sep 15;154:237-245
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, Wang C, Chen J, Liu Y, Machens HG, Chen Z
Life sciences 2020 Sep 1;256:118022
Life sciences 2020 Sep 1;256:118022
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities.
Chen Y, Xie X, Wang C, Hu Y, Zhang H, Zhang L, Tu S, He Y, Li Y
Cell death & disease 2020 Sep 1;11(8):712
Cell death & disease 2020 Sep 1;11(8):712
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Lv S, Yuan P, Dong J, Lu C, Li M, Qu F, Zhu Y, Yuan Z, Zhang J
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Activated FMS-like tyrosine kinase 3 ameliorates angiotensin II-induced cardiac remodelling.
Ma W, Liang F, Zhan H, Jiang X, Gao C, Zhang X, Zhang K, Sun Q, Hu H, Zhao Z
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Acta physiologica (Oxford, England) 2020 Oct;230(2):e13519
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
Yu X, Fan H, Jiang X, Zheng W, Yang Y, Jin M, Ma X, Jiang W
Oncology letters 2020 Oct;20(4):52
Oncology letters 2020 Oct;20(4):52
Phosphorylation of PRAS40 contributes to the activation of the PI3K/AKT/mTOR signaling pathway and the inhibition of autophagy following status epilepticus in rats.
Lin J, Fang Y, Zhang M, Wang X, Li L, He M, Xue A, Zhu K, Shen Y, Li B
Experimental and therapeutic medicine 2020 Oct;20(4):3625-3632
Experimental and therapeutic medicine 2020 Oct;20(4):3625-3632
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.
Torkzaban B, Natarajaseenivasan K, Mohseni Ahooyi T, Shekarabi M, Amini S, Langford TD, Khalili K
Cell death & disease 2020 Oct 8;11(10):835
Cell death & disease 2020 Oct 8;11(10):835
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
Zhai C, Feng W, Shi W, Wang J, Zhang Q, Yan X, Wang Q, Li S, Liu L, Pan Y, Zhu Y, Chai L, Li C, Liu P, Chen Y, Li M
European journal of pharmacology 2020 Oct 5;884:173302
European journal of pharmacology 2020 Oct 5;884:173302
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Lu J, Meng Z, Chen Y, Yu L, Gao B, Zheng Y, Guan S
Food & function 2020 Oct 21;11(10):9208-9215
Food & function 2020 Oct 21;11(10):9208-9215
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, Li L, Zhao Y
Brain research 2020 Oct 15;1745:146948
Brain research 2020 Oct 15;1745:146948
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Sun Y, He L, Wang T, Hua W, Qin H, Wang J, Wang L, Gu W, Li T, Li N, Liu X, Chen F, Tang L
Molecular neurobiology 2020 Nov;57(11):4628-4641
Molecular neurobiology 2020 Nov;57(11):4628-4641
CdSe/ZnS quantum dots induced spermatogenesis dysfunction via autophagy activation.
Yang Q, Li F, Miao Y, Luo X, Dai S, Liu J, Niu W, Sun Y
Journal of hazardous materials 2020 Nov 5;398:122327
Journal of hazardous materials 2020 Nov 5;398:122327
[IL-17A/lL-17RA reduces cisplatin sensitivity of ovarian cancer SKOV3 cells by regulating autophagy].
Wang L, Zhang X, Wang L, Wang B, Zhang J, Li Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Nov 30;40(11):1550-1556
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Nov 30;40(11):1550-1556
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Ding S, Ma N, Liu H, Tang M, Mei J
Aging 2020 Nov 24;12(24):25505-25527
Aging 2020 Nov 24;12(24):25505-25527
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative.
Üner G, Tag Ö, Erzurumlu Y, Kirmizibayrak PB, Bedir E
Chemical research in toxicology 2020 Nov 16;33(11):2880-2891
Chemical research in toxicology 2020 Nov 16;33(11):2880-2891
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Shao CS, Zhou XH, Zheng XX, Huang Q
Journal of ethnopharmacology 2020 Nov 15;262:113213
Journal of ethnopharmacology 2020 Nov 15;262:113213
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A, Xia H
Nature communications 2020 Nov 12;11(1):5731
Nature communications 2020 Nov 12;11(1):5731
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D
Chemico-biological interactions 2020 Nov 1;331:109279
Chemico-biological interactions 2020 Nov 1;331:109279
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.
Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J
Ecotoxicology and environmental safety 2020 May;194:110414
Ecotoxicology and environmental safety 2020 May;194:110414
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Zeng Y, Guo Z, Hu Z, Liu M, Chen Y, Chen S, Peng B, Zhang P, Wu Z, Luo H, Zhong F, Jiang K, Lu Y, Yuan G, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD
Nature communications 2020 May 8;11(1):2306
Nature communications 2020 May 8;11(1):2306
Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Tian Y, Guo H, Miao X, Xu J, Yang R, Zhao L, Liu J, Yang L, Gao F, Zhang W, Liu Q, Sun S, Tian Y, Li H, Huang J, Gu C, Liu S, Feng X
Cell death & disease 2020 May 5;11(5):319
Cell death & disease 2020 May 5;11(5):319
The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway.
Shao Q, Liu T, Wang W, Duan Q, Liu T, Xu L, Huang G, Chen Z
Journal of ethnopharmacology 2020 May 23;254:112611
Journal of ethnopharmacology 2020 May 23;254:112611
NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway.
Luo S, Shao L, Chen Z, Hu D, Jiang L, Tang W
Experimental cell research 2020 May 15;390(2):111981
Experimental cell research 2020 May 15;390(2):111981
UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Chen T, Zhang W, Huang B, Chen X, Huang C
Cells 2020 May 13;9(5)
Cells 2020 May 13;9(5)
Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy.
Lin DS, Ho CS, Huang YW, Wu TY, Lee TH, Huang ZD, Wang TJ, Yang SJ, Chiang MF
Cells 2020 May 1;9(5)
Cells 2020 May 1;9(5)
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Yan K, Wu C, Ye Y, Li L, Wang X, He W, Ren S, Xu Y
Cell proliferation 2020 Mar;53(3):e12778
Cell proliferation 2020 Mar;53(3):e12778
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Lyu ZS, Cao XN, Wen Q, Mo XD, Zhao HY, Chen YH, Wang Y, Chang YJ, Xu LP, Zhang XH, Kong Y, Huang XJ
EBioMedicine 2020 Mar;53:102677
EBioMedicine 2020 Mar;53:102677
Autophagic-CTSB-inflammasome axis modulates hepatic stellate cells activation in arsenic-induced liver fibrosis.
Tao Y, Qiu T, Yao X, Jiang L, Wang N, Jia X, Wei S, Wang Z, Pei P, Zhang J, Zhu Y, Yang G, Liu X, Liu S, Sun X
Chemosphere 2020 Mar;242:124959
Chemosphere 2020 Mar;242:124959
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, Hardt M, Koeppel A, Roderfeld M, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
Zhu B, Jiang Q, Que G, Dai Z, Wu Y
Journal of oral science 2020 Mar 28;62(2):184-188
Journal of oral science 2020 Mar 28;62(2):184-188
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
Li K, Deng Y, Deng G, Chen P, Wang Y, Wu H, Ji Z, Yao Z, Zhang X, Yu B, Zhang K
Stem cell research & therapy 2020 Mar 20;11(1):131
Stem cell research & therapy 2020 Mar 20;11(1):131
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Choi I, Zhang Y, Seegobin SP, Pruvost M, Wang Q, Purtell K, Zhang B, Yue Z
Nature communications 2020 Mar 13;11(1):1386
Nature communications 2020 Mar 13;11(1):1386
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G
European journal of medicinal chemistry 2020 Mar 1;189:112076
European journal of medicinal chemistry 2020 Mar 1;189:112076
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M
Oncogene 2020 Jun;39(23):4551-4566
Oncogene 2020 Jun;39(23):4551-4566
Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Zhou H, Xu C, Lee H, Yoon Y, Chen W
Molecular metabolism 2020 Jun;36:100971
Molecular metabolism 2020 Jun;36:100971
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
Environmental science and pollution research international 2020 Jun;27(18):22980-22988
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Mooli RGR, Mukhi D, Watt M, Edmunds L, Xie B, Capooci J, Reslink M, Eze C, Mills A, Stolz DB, Jurczak M, Ramakrishnan SK
Metabolism: clinical and experimental 2020 Jun;107:154225
Metabolism: clinical and experimental 2020 Jun;107:154225
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis.
Chang Y, Xia L, Song M, Tang M, Patpur BK, Li J, Yang W, Yang C
Life sciences 2020 Jun 15;251:117595
Life sciences 2020 Jun 15;251:117595
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
Siderophores induce mitophagy-dependent apoptosis in platelets.
Wang W, Lu Y, Wang Y, Zhang Y, Xia B, Cao J
Annals of translational medicine 2020 Jul;8(14):879
Annals of translational medicine 2020 Jul;8(14):879
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.
Liu H, You L, Wu J, Zhao M, Guo R, Zhang H, Su R, Mao Q, Deng D, Hao Y
Journal of leukocyte biology 2020 Jul;108(1):253-266
Journal of leukocyte biology 2020 Jul;108(1):253-266
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Pang C, Song C, Li Y, Wang Q, Zhu X, Wu J, Tian Y, Fan H, Hu J, Li C, Wang B, Li X, Liu W, Fan L
Nanoscale research letters 2020 Jul 8;15(1):143
Nanoscale research letters 2020 Jul 8;15(1):143
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Mei ZG, Huang YG, Feng ZT, Luo YN, Yang SB, Du LP, Jiang K, Liu XL, Fu XY, Deng YH, Zhou HJ
Aging 2020 Jul 3;12(13):13187-13205
Aging 2020 Jul 3;12(13):13187-13205
Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss.
Zhang L, Qi M, Chen J, Zhao J, Li L, Hu J, Jin Y, Liu W
Stem cell research & therapy 2020 Jul 3;11(1):269
Stem cell research & therapy 2020 Jul 3;11(1):269
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy.
Sorrentino ZA, Hass E, Vijayaraghavan N, Gorion KM, Riffe CJ, Dhillon JS, Giasson BI
Neuroscience letters 2020 Jul 27;732:135017
Neuroscience letters 2020 Jul 27;732:135017
Dehydroandrographolide inhibits mastitis by activating autophagy without affecting intestinal flora.
Guo W, Liu J, Zhang Y, Ma H, Li Y, Gong Q, Cao Y, Hu G, Xie S, Fu S
Aging 2020 Jul 23;12(14):14050-14065
Aging 2020 Jul 23;12(14):14050-14065
Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
Liu L, Chen S, Yu M, Ge C, Ren M, Liu B, Yang X, Christian TW Jr, Hou YM, Zou J, Zhu WG, Luo J
Cell death & disease 2020 Jul 23;11(7):563
Cell death & disease 2020 Jul 23;11(7):563
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
Zheng X, Wei J, Li W, Li X, Wang W, Guo J, Fu Z
Aging 2020 Jul 20;12(16):16390-16409
Aging 2020 Jul 20;12(16):16390-16409
N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
Chen YC, Navarrete MS, Wang Y, McClintock NC, Sakurai R, Wang F, Chen KT, Chou TF, Rehan VK, Lee DJ, Diaz B
Scientific reports 2020 Jul 20;10(1):11952
Scientific reports 2020 Jul 20;10(1):11952
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Xiang Q, Wan P, Yang G, Huang S, Qin M, Yang H, Luo Z, Wu K, Wu J
Viruses 2020 Jul 14;12(7)
Viruses 2020 Jul 14;12(7)
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, Fu J
Life sciences 2020 Jul 1;252:117662
Life sciences 2020 Jul 1;252:117662
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, Li Y, Gong Q, Cao Y, Cheng J, Fu S
International immunopharmacology 2020 Jan;78:105983
International immunopharmacology 2020 Jan;78:105983
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, Ren L
Cell biology international 2020 Jan;44(1):127-136
Cell biology international 2020 Jan;44(1):127-136
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335
EMBO reports 2020 Jan 7;21(1):e48335
A robust TDP-43 knock-in mouse model of ALS.
Huang SL, Wu LS, Lee M, Chang CW, Cheng WC, Fang YS, Chen YR, Cheng PL, Shen CJ
Acta neuropathologica communications 2020 Jan 21;8(1):3
Acta neuropathologica communications 2020 Jan 21;8(1):3
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.
Wang Y, Liang HX, Zhang CM, Zou M, Zou BB, Wei W, Hu W
Translational cancer research 2020 Feb;9(2):937-948
Translational cancer research 2020 Feb;9(2):937-948
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Wu Q, Zhang M, Liu X, Zhang J, Wang H
International journal of molecular medicine 2020 Feb;45(2):475-484
International journal of molecular medicine 2020 Feb;45(2):475-484
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Chen M, Zhu LL, Su JL, Li GL, Wang J, Zhang YN
Human & experimental toxicology 2020 Feb;39(2):173-181
Human & experimental toxicology 2020 Feb;39(2):173-181
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.
Li Z, Li H, Xu X, Wang L, Liu B, Zheng W, Lian L, Song Y, Xia X, Hou L, Cheng H, Zhou R
Cell death and differentiation 2020 Feb;27(2):556-572
Cell death and differentiation 2020 Feb;27(2):556-572
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
Hu LD, Wang J, Chen XJ, Yan YB
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
Ying C, Ying L, Yanxia L, Le W, Lili C
Acta histochemica 2020 Feb;122(2):151485
Acta histochemica 2020 Feb;122(2):151485
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Lou L, Tian M, Chang J, Li F, Zhang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.
Li G, Song Y, Liao Z, Wang K, Luo R, Lu S, Zhao K, Feng X, Liang H, Ma L, Wang B, Ke W, Yin H, Zhan S, Li S, Wu X, Zhang Y, Yang C
Cell death & disease 2020 Feb 6;11(2):103
Cell death & disease 2020 Feb 6;11(2):103
Nobiletin Triggers Reactive Oxygen Species-Mediated Pyroptosis through Regulating Autophagy in Ovarian Cancer Cells.
Zhang R, Chen J, Mao L, Guo Y, Hao Y, Deng Y, Han X, Li Q, Liao W, Yuan M
Journal of agricultural and food chemistry 2020 Feb 5;68(5):1326-1336
Journal of agricultural and food chemistry 2020 Feb 5;68(5):1326-1336
Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine.
Ke X, Qin Q, Deng T, Liao Y, Gao SJ
Cancers 2020 Feb 5;12(2)
Cancers 2020 Feb 5;12(2)
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34.
Xie W, Jin S, Wu Y, Xian H, Tian S, Liu DA, Guo Z, Cui J
Cell reports 2020 Feb 25;30(8):2807-2819.e4
Cell reports 2020 Feb 25;30(8):2807-2819.e4
Silencing DAPK3 blocks the autophagosome-lysosome fusion by mediating SNAP29 in trophoblast cells under high glucose treatment.
Wang Y, Ji L, Peng Z, Lai R, Zhang X, Xu Y, Chen Z, Liu R, Zhong Y, Hu H, Wang L
Molecular and cellular endocrinology 2020 Feb 15;502:110674
Molecular and cellular endocrinology 2020 Feb 15;502:110674
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
Pan G, Jin L, Shen W, Zhang J, Pan J, Cheng J, Xie Q, Hu Q, Wu S, Zhang H, Chen X
Life sciences 2020 Feb 15;243:117279
Life sciences 2020 Feb 15;243:117279
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Liu J, Zhu Z, Liu Y, Wei L, Li B, Mao F, Zhang J, Wang Y, Liu Y
Life sciences 2020 Feb 1;242:117228
Life sciences 2020 Feb 1;242:117228
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Zhu L, Duan W, Wu G, Zhang D, Wang L, Chen D, Chen Z, Yang B
Annals of translational medicine 2020 Dec;8(23):1586
Annals of translational medicine 2020 Dec;8(23):1586
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938
Neurochemical research 2020 Dec;45(12):2926-2938
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Nordgren KKS, Wallace KB
Cardiovascular toxicology 2020 Dec;20(6):557-570
Cardiovascular toxicology 2020 Dec;20(6):557-570
Identification of curcumin as a novel natural inhibitor of rDNA transcription.
Xu Y, Wu Y, Wang L, Qian C, Wang Q, Wan W
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3362-3374
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3362-3374
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Xu J, Wang Z, Huang Y, Wang Y, Xiang L, He X
Steroids 2020 Dec;164:108737
Steroids 2020 Dec;164:108737
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis.
Chen W, Wang H, Zhu Z, Feng J, Chen L
Molecular therapy. Nucleic acids 2020 Dec 4;22:657-672
Molecular therapy. Nucleic acids 2020 Dec 4;22:657-672
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
Chen Y, Shen J, Qi G, Zha Q, Zhang C, Yao W, Gao X, Chen S
Neuropharmacology 2020 Dec 15;181:108335
Neuropharmacology 2020 Dec 15;181:108335
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Aras S, Purandare N, Gladyck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Li L, Xie P, Lin W, Liu J, Chen J, Guo Z, Bin C, An W, Zhang C, Zhan Y
Experimental cell research 2020 Dec 1;397(1):112341
Experimental cell research 2020 Dec 1;397(1):112341
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869
Cell proliferation 2020 Aug;53(8):e12869
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways.
Zhang Q, Wang X, Cao S, Sun Y, He X, Jiang B, Yu Y, Duan J, Qiu F, Kang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110245
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110245
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
Bengoechea R, Findlay AR, Bhadra AK, Shao H, Stein KC, Pittman SK, Daw JA, Gestwicki JE, True HL, Weihl CC
The Journal of clinical investigation 2020 Aug 3;130(8):4470-4485
The Journal of clinical investigation 2020 Aug 3;130(8):4470-4485
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Xie H, Li X, Yang W, Yu L, Jiang X, Chen Y, Shen Z, Li C, Gu M, Shi L
International journal of molecular sciences 2020 Aug 13;21(16)
International journal of molecular sciences 2020 Aug 13;21(16)
NAD(+) administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Zhang YJ, Zhang M, Zhao X, Shi K, Ye M, Tian J, Guan S, Ying W, Qu X
Basic research in cardiology 2020 Aug 10;115(5):57
Basic research in cardiology 2020 Aug 10;115(5):57
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Guo X, Zhang Y, Lu C, Qu F, Jiang X
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):714-724
Artemisinin Attenuated Atherosclerosis in High-Fat Diet-Fed ApoE-/- Mice by Promoting Macrophage Autophagy Through the AMPK/mTOR/ULK1 Pathway.
Cao Q, Du H, Fu X, Duan N, Liu C, Li X
Journal of cardiovascular pharmacology 2020 Apr;75(4):321-332
Journal of cardiovascular pharmacology 2020 Apr;75(4):321-332
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
Koller EJ, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz PE, Ryu D, Golde TE, Sullivan PM, Lewis J, Borchelt DR, Chakrabarty P
Molecular neurobiology 2020 Apr;57(4):1986-2001
Molecular neurobiology 2020 Apr;57(4):1986-2001
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
Shi W, Ma H, Liu T, Yan D, Luo P, Zhai M, Tao J, Huo S, Guo J, Li C, Lin J, Zhang C, Li S, Lv J, Lin L
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Journal of cellular and molecular medicine 2020 Apr;24(8):4748-4761
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Liu K, Chen P, Lu J, Zhu Y, Xu Y, Liu Y, Liu J
Biological trace element research 2020 Apr;194(2):570-580
Biological trace element research 2020 Apr;194(2):570-580
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, Xu M, Ma Y, Wang J, Zhang Q, Wei P
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases.
Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, Prokop S, Dickson DW, Yachnis AT, Giasson BI
Journal of neuropathology and experimental neurology 2020 Apr 1;79(4):407-418
Journal of neuropathology and experimental neurology 2020 Apr 1;79(4):407-418
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Zhang L, Zhou Y, Xia Q, Chen Y, Li J
Toxicology letters 2020 Apr 1;322:77-86
Toxicology letters 2020 Apr 1;322:77-86
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Yu M, Yang J, Gao X, Sun W, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Qin A, Zhong T, Zou H, Wan X, Yao B, Zheng X, Yin D
Cell & bioscience 2019;9:13
Cell & bioscience 2019;9:13
Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
Jiang J, Chen S, Li K, Zhang C, Tan Y, Deng Q, Chai Y, Wang X, Chen G, Feng K, Zhang L, Xie CM, Ma K
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):499-510
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Guo Y, Pei X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428
Oxidative medicine and cellular longevity 2019;2019:4032428
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Wu X, Sun R, Wang H, Yang B, Wang F, Xu H, Chen S, Zhao R, Pi J, Xu Y
Oxidative medicine and cellular longevity 2019;2019:1038932
Oxidative medicine and cellular longevity 2019;2019:1038932
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, Huang X, Xia G, Huang X
Cancer cell international 2019;19:7
Cancer cell international 2019;19:7
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, You C, Peng S, Tang G, Yang C, Sun W, Li S, Mao Y, Xu J, Xiao Y, Gong Y, Quan H, Xie C
International journal of biological sciences 2019;15(5):999-1009
International journal of biological sciences 2019;15(5):999-1009
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
The up-regulation of P62 levels is associated with resistance of sorafenib in hepatocarcinoma cells.
Pan J, Lu C, Jun W, Wu Y, Shi X, Ding Y
International journal of clinical and experimental pathology 2019;12(7):2622-2630
International journal of clinical and experimental pathology 2019;12(7):2622-2630
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677
OncoTargets and therapy 2019;12:5661-5677
The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress.
Zheng Y, Tu J, Wang X, Yu Y, Li J, Jin Y, Wu J
OncoTargets and therapy 2019;12:10187-10198
OncoTargets and therapy 2019;12:10187-10198
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, Zhou S, Jiang Y, Yang X, Zhang R, Shen L
American journal of translational research 2019;11(4):2042-2055
American journal of translational research 2019;11(4):2042-2055
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, Cai D, Rui J, Zhang L
Frontiers in pharmacology 2019;10:676
Frontiers in pharmacology 2019;10:676
Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells.
Chen Z, Tian D, Liao X, Zhang Y, Xiao J, Chen W, Liu Q, Chen Y, Li D, Zhu L, Cai S
Frontiers in pharmacology 2019;10:260
Frontiers in pharmacology 2019;10:260
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, Zhao L
Neurotoxicology 2019 Sep;74:74-80
Neurotoxicology 2019 Sep;74:74-80
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Pan Y, Li Z, Wang Y, Yan M, Wu J, Beharee RG, Yu J
Journal of cellular physiology 2019 Sep;234(9):16114-16124
Journal of cellular physiology 2019 Sep;234(9):16114-16124
Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate ameliorates pressure overload-induced cardiac hypertrophy and dysfunction through inhibiting autophagy.
Wang B, Shen D, Tang J, Li J, Xiao Y, Chen X, Cao C, Han D, Gao E, Zhao W, Zhang J, Chang J
Journal of cellular and molecular medicine 2019 Sep;23(9):6048-6059
Journal of cellular and molecular medicine 2019 Sep;23(9):6048-6059
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, Duan H, Huang Z, Wu Q
Molecular medicine reports 2019 Sep;20(3):2867-2874
Molecular medicine reports 2019 Sep;20(3):2867-2874
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Wang F, Lei X, Zhao Y, Yu Q, Li Q, Zhao H, Pei Z
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, Lian S
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
Xu D, Jiang X, He H, Liu D, Yang L, Chen H, Wu L, Geng G, Li Q
Life sciences 2019 Sep 1;232:116639
Life sciences 2019 Sep 1;232:116639
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
Zhou Y, Tao X, Wang Z, Feng L, Wang L, Liu X, Pan R, Liao Y, Chang Q
International journal of molecular sciences 2019 Sep 1;20(17)
International journal of molecular sciences 2019 Sep 1;20(17)
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Li CF, Pan YK, Gao Y, Shi F, Wang YC, Sun XQ
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Krüppel‑like factor 4 ameliorates diabetic kidney disease by activating autophagy via the mTOR pathway.
Gong J, Zhan H, Li Y, Zhang W, Jin J, He Q
Molecular medicine reports 2019 Oct;20(4):3240-3248
Molecular medicine reports 2019 Oct;20(4):3240-3248
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836
Journal of diabetes 2019 Oct;11(10):826-836
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT
Acta neuropathologica communications 2019 Oct 30;7(1):158
Acta neuropathologica communications 2019 Oct 30;7(1):158
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
Krans A, Skariah G, Zhang Y, Bayly B, Todd PK
Acta neuropathologica communications 2019 Oct 30;7(1):152
Acta neuropathologica communications 2019 Oct 30;7(1):152
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Lu Q, Tan S, Gu W, Li F, Hua W, Zhang S, Chen F, Tang L
Journal of ethnopharmacology 2019 Oct 28;243:112089
Journal of ethnopharmacology 2019 Oct 28;243:112089
Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells.
Hu B, Song W, Tang Y, Shi M, Li H, Yu D
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
Animals : an open access journal from MDPI 2019 Oct 21;9(10)
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Wei W, Lu M, Lan X, Liu N, Wang H, Du J, Sun T, Li Y, Yu J
Neuroscience letters 2019 Oct 15;711:134415
Neuroscience letters 2019 Oct 15;711:134415
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
Yu S, Wang X, Dou N, Zhou J, Gao Y, Li Y
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Wang Z, Zhang M, Shan R, Wang YJ, Chen J, Huang J, Sun LQ, Zhou WB
Oncology reports 2019 Nov;42(5):1915-1923
Oncology reports 2019 Nov;42(5):1915-1923
Mitophagy protects against statin-mediated skeletal muscle toxicity.
Ramesh M, Campos JC, Lee P, Song Y, Hernandez G, Sin J, Tucker KC, Saadaeijahromi H, Gurney M, Ferreira JCB, Andres AM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11857-11869
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11857-11869
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Kuang M, Li L, Li C, Wang G
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
Xu WN, Zheng HL, Yang RZ, Liu T, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, Wang Y, Huang Y, Zhang J, Li Q
International journal of oncology 2019 May;54(5):1601-1612
International journal of oncology 2019 May;54(5):1601-1612
Dihydroartemisinin, an antimalarial drug, induces absent in melanoma 2 inflammasome activation and autophagy in human hepatocellular carcinoma HepG2215 cells.
Shi X, Wang L, Ren L, Li J, Li S, Cui Q, Li S
Phytotherapy research : PTR 2019 May;33(5):1413-1425
Phytotherapy research : PTR 2019 May;33(5):1413-1425
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
Dhillon JS, Trejo-Lopez JA, Riffe C, Levites Y, Sacino AN, Borchelt DR, Yachnis AY, Giasson BI
Acta neuropathologica communications 2019 May 20;7(1):80
Acta neuropathologica communications 2019 May 20;7(1):80
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F
Cell reports 2019 May 14;27(7):2075-2091.e5
Cell reports 2019 May 14;27(7):2075-2091.e5
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Wang Y, Meng C, Zhang J, Wu J, Zhao J
International immunopharmacology 2019 Mar;68:234-241
International immunopharmacology 2019 Mar;68:234-241
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Gu X, Han M, Du Y, Wu Y, Xu Y, Zhou X, Ye D, Wang HL
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Carfilzomib enhances cisplatin-induced apoptosis in SK-N-BE(2)-M17 human neuroblastoma cells.
Lee SI, Jeong YJ, Yu AR, Kwak HJ, Cha JY, Kang I, Yeo EJ
Scientific reports 2019 Mar 25;9(1):5039
Scientific reports 2019 Mar 25;9(1):5039
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte.
Jin J, Shi Y, Gong J, Zhao L, Li Y, He Q, Huang H
Stem cell research & therapy 2019 Mar 15;10(1):95
Stem cell research & therapy 2019 Mar 15;10(1):95
LncRNA ENST00000453774.1 contributes to oxidative stress defense dependent on autophagy mediation to reduce extracellular matrix and alleviate renal fibrosis.
Xiao X, Yuan Q, Chen Y, Huang Z, Fang X, Zhang H, Peng L, Xiao P
Journal of cellular physiology 2019 Jun;234(6):9130-9143
Journal of cellular physiology 2019 Jun;234(6):9130-9143
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
Wu J, Kuang L, Chen C, Yang J, Zeng WN, Li T, Chen H, Huang S, Fu Z, Li J, Liu R, Ni Z, Chen L, Yang L
Biomaterials 2019 Jun;206:87-100
Biomaterials 2019 Jun;206:87-100
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Arhzaouy K, Papadopoulos C, Schulze N, Pittman SK, Meyer H, Weihl CC
Autophagy 2019 Jun;15(6):1082-1099
Autophagy 2019 Jun;15(6):1082-1099
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, Melki R, Gitler AD
Acta neuropathologica 2019 Jun;137(6):961-980
Acta neuropathologica 2019 Jun;137(6):961-980
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Jiang R, Zhou Z, Liao Y, Yang F, Cheng Y, Huang J, Wang J, Chen H, Zhu T, Chao J
Toxicology letters 2019 Jun 1;307:26-40
Toxicology letters 2019 Jun 1;307:26-40
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Zhu J, Li J, Wang X, Feng X, Li Y
The new microbiologica 2019 Jul;42(3):161-165
The new microbiologica 2019 Jul;42(3):161-165
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, Zhang G
Human & experimental toxicology 2019 Jul;38(7):794-802
Human & experimental toxicology 2019 Jul;38(7):794-802
Taurine protects against arsenic trioxide-induced insulin resistance via ROS-Autophagy pathway in skeletal muscle.
Yang L, Qiu T, Yao X, Jiang L, Wei S, Pei P, Wang Z, Bai J, Liu X, Yang G, Liu S, Sun X
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
The international journal of biochemistry & cell biology 2019 Jul;112:50-60
SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling.
Hou B, Wang G, Gao Q, Wei Y, Zhang C, Wang Y, Huo Y, Yang H, Jiang X, Xi Z
Scientific reports 2019 Jul 31;9(1):11087
Scientific reports 2019 Jul 31;9(1):11087
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
Lu J, Li Z, Wu X, Chen Y, Yan M, Ge X, Yu J
Stem cell research & therapy 2019 Jul 29;10(1):222
Stem cell research & therapy 2019 Jul 29;10(1):222
ERβ promotes Aβ degradation via the modulation of autophagy.
Wei Y, Zhou J, Wu J, Huang J
Cell death & disease 2019 Jul 22;10(8):565
Cell death & disease 2019 Jul 22;10(8):565
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Khan N, Yılmaz S, Aksoy S, Uzel A, Tosun Ç, Kirmizibayrak PB, Bedir E
Chemico-biological interactions 2019 Jul 1;307:167-178
Chemico-biological interactions 2019 Jul 1;307:167-178
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
Luo R, Liao Z, Song Y, Yin H, Zhan S, Li G, Ma L, Lu S, Wang K, Li S, Zhang Y, Yang C
Life sciences 2019 Jul 1;228:85-97
Life sciences 2019 Jul 1;228:85-97
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Chen Z, Jiang Q, Zhu P, Chen Y, Xie X, Du Z, Jiang L, Tang W
The Prostate 2019 Jan;79(1):44-53
The Prostate 2019 Jan;79(1):44-53
Alterations of autophagy in knee cartilage by treatment with treadmill exercise in a rat osteoarthritis model.
Zhang X, Yang Y, Li X, Zhang H, Gang Y, Bai L
International journal of molecular medicine 2019 Jan;43(1):336-344
International journal of molecular medicine 2019 Jan;43(1):336-344
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.
Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):652-667
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):652-667
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Zhang Z, Zhang M, Liu H, Yin W
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Zhang WX, He BM, Wu Y, Qiao JF, Peng ZY
Life sciences 2019 Jan 15;217:8-15
Life sciences 2019 Jan 15;217:8-15
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, Tian Y
Toxins 2019 Jan 15;11(1)
Toxins 2019 Jan 15;11(1)
Autophagy protects against redox-active trace metal-induced cell death in rabbit synovial fibroblasts through Toll-like receptor 4 activation.
Alsousi AA, Igwe OJ
Experimental cell research 2019 Jan 1;374(1):19-28
Experimental cell research 2019 Jan 1;374(1):19-28
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Taurine protected As(2)O(3)-induced the activation of hepatic stellate cells through inhibiting PPARα-autophagy pathway.
Wang Z, Tao Y, Qiu T, Yao X, Jiang L, Wang N, Wei S, Jia X, Pei P, Yang G, Liu X, Liu S, Sun X
Chemico-biological interactions 2019 Feb 25;300:123-130
Chemico-biological interactions 2019 Feb 25;300:123-130
Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells.
Cheng SY, Chen NF, Lin PY, Su JH, Chen BH, Kuo HM, Sung CS, Sung PJ, Wen ZH, Chen WF
Cancers 2019 Feb 14;11(2)
Cancers 2019 Feb 14;11(2)
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Meng Y, Pan M, Zheng B, Chen Y, Li W, Yang Q, Zheng Z, Sun N, Zhang Y, Li X
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Loss of HMBOX1 promotes LPS-induced apoptosis and inhibits LPS-induced autophagy of vascular endothelial cells in mouse.
Ma H, Su L, He X, Miao J
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):946-957
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):946-957
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
FAM134B improves preadipocytes differentiation by enhancing mitophagy.
Cai M, Zhao J, Liu Q, Wang X, Wang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158508
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Dec;1864(12):158508
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Wang N, Yang B, Muhetaer G, Wang S, Zheng Y, Lu J, Li M, Zhang F, Situ H, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition.
Qin S, Jiang C, Gao J
Biomedical reports 2019 Dec;11(6):241-252
Biomedical reports 2019 Dec;11(6):241-252
Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.
Wang J, Li L, Wang J, Song L, Tan N, Wang Z
Cells 2019 Dec 7;8(12)
Cells 2019 Dec 7;8(12)
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress.
You Z, Jiang WX, Qin LY, Gong Z, Wan W, Li J, Wang Y, Zhang H, Peng C, Zhou T, Tang C, Liu W
Nature communications 2019 Dec 19;10(1):5792
Nature communications 2019 Dec 19;10(1):5792
A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway.
Zhang Y, Cao Y, Chen J, Qin H, Yang L
Journal of agricultural and food chemistry 2019 Dec 18;67(50):13948-13959
Journal of agricultural and food chemistry 2019 Dec 18;67(50):13948-13959
Solanesol derived therapeutic carriers for anticancer drug delivery.
Xiong Y, Hou T, Liu L, Peng W, Wang C, Lu Y, Wang S, Shi J, Song S
International journal of pharmaceutics 2019 Dec 15;572:118823
International journal of pharmaceutics 2019 Dec 15;572:118823
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C
Nature communications 2019 Dec 12;10(1):5681
Nature communications 2019 Dec 12;10(1):5681
Zearalenone induces NLRP3-dependent pyroptosis via activation of NF-κB modulated by autophagy in INS-1 cells.
Wang X, Jiang L, Shi L, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Wang Y, Liu X
Toxicology 2019 Dec 1;428:152304
Toxicology 2019 Dec 1;428:152304
Quercetin shows anti-tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway.
Wu L, Li J, Liu T, Li S, Feng J, Yu Q, Zhang J, Chen J, Zhou Y, Ji J, Chen K, Mao Y, Wang F, Dai W, Fan X, Wu J, Guo C
Cancer medicine 2019 Aug;8(10):4806-4820
Cancer medicine 2019 Aug;8(10):4806-4820
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, Chen D, Diao Y, Almoiliqy M, Wang L
Pharmacological research 2019 Aug;146:104308
Pharmacological research 2019 Aug;146:104308
SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function.
Wang P, Wang L, Lu J, Hu Y, Wang Q, Li Z, Cai S, Liang L, Guo K, Xie J, Wang J, Lan R, Shen J, Liu P
Journal of molecular and cellular cardiology 2019 Aug;133:125-137
Journal of molecular and cellular cardiology 2019 Aug;133:125-137
Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice.
Chen Z, Yang D, Jiang X, Tian L, Sun J, Tian D, Bai W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Aug;130:1-11
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Aug;130:1-11
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.
Lu H, Xiao J, Ke C, Ni X, Xiu R, Tian Q, Pan H, Zou L, Wang F, Ma T, Ji X, Yuan P, Liu L, Zhang J, Jia W, Duan Q, Zhu F
Cell death & disease 2019 Aug 5;10(8):583
Cell death & disease 2019 Aug 5;10(8):583
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Li T, Wen L, Cheng B
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Liu H, Sun Y, Zhang Y, Yang G, Guo L, Zhao Y, Pei Z
Inflammation 2019 Apr;42(2):516-525
Inflammation 2019 Apr;42(2):516-525
Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease.
Barriocanal-Casado E, Hidalgo-Gutiérrez A, Raimundo N, González-García P, Acuña-Castroviejo D, Escames G, López LC
EBioMedicine 2019 Apr;42:511-523
EBioMedicine 2019 Apr;42:511-523
Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy.
Gao N, Yao X, Jiang L, Yang L, Qiu T, Wang Z, Pei P, Yang G, Liu X, Sun X
Journal of cellular physiology 2019 Apr;234(4):5143-5152
Journal of cellular physiology 2019 Apr;234(4):5143-5152
Silver nanoparticles induce protective autophagy via Ca(2+)/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Li L, Li L, Zhou X, Yu Y, Li Z, Zuo D, Wu Y
Nanotoxicology 2019 Apr;13(3):369-391
Nanotoxicology 2019 Apr;13(3):369-391
Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy.
Sun CY, Nie J, Zheng ZL, Zhao J, Wu LM, Zhu Y, Su ZQ, Zheng GJ, Feng B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108647
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108647
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.
Chen P, Geng N, Zhou D, Zhu Y, Xu Y, Liu K, Liu Y, Liu J
Ecotoxicology and environmental safety 2019 Apr 15;170:112-119
Ecotoxicology and environmental safety 2019 Apr 15;170:112-119
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
Yang J, Xu J, Han X, Wang H, Zhang Y, Dong J, Deng Y, Wang J
Frontiers in physiology 2018;9:1315
Frontiers in physiology 2018;9:1315
Activation of Cyclooxygenase-2 by ATF4 During Endoplasmic Reticulum Stress Regulates Kidney Podocyte Autophagy Induced by Lupus Nephritis.
Jin J, Zhao L, Zou W, Shen W, Zhang H, He Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):753-764
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):753-764
3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation.
Wang L, Li X, Chen C
Biomedical research (Tokyo, Japan) 2018;39(2):87-94
Biomedical research (Tokyo, Japan) 2018;39(2):87-94
Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.
Wang Y, Jiang SW, Liu X, Niu L, Ge XL, Zhang JC, Wang HR, Fei AH, Gao CJ, Pan SM
Oxidative medicine and cellular longevity 2018;2018:4612727
Oxidative medicine and cellular longevity 2018;2018:4612727
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Mo W, Wang C, Li J, Chen K, Xia Y, Li S, Xu L, Lu X, Wang W, Guo C
Gastroenterology research and practice 2018;2018:2824139
Gastroenterology research and practice 2018;2018:2824139
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis.
Lin HH, Chung Y, Cheng CT, Ouyang C, Fu Y, Kuo CY, Chi KK, Sadeghi M, Chu P, Kung HJ, Li CF, Limesand KH, Ann DK
Autophagy 2018;14(9):1481-1498
Autophagy 2018;14(9):1481-1498
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Han B, Zhang Y, Zhang Y, Bai Y, Chen X, Huang R, Wu F, Leng S, Chao J, Zhang JH, Hu G, Yao H
Autophagy 2018;14(7):1164-1184
Autophagy 2018;14(7):1164-1184
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z
Autophagy 2018;14(2):336-346
Autophagy 2018;14(2):336-346
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, Lv Y, Liu Q, Guo C, Zhou Y
Drug design, development and therapy 2018;12:4067-4082
Drug design, development and therapy 2018;12:4067-4082
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Zhang J, Liu L, Xue Y, Ma Y, Liu X, Li Z, Li Z, Liu Y
Frontiers in molecular neuroscience 2018;11:92
Frontiers in molecular neuroscience 2018;11:92
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Liang S, Jin J, Shen X, Jiang X, Li Y, He Q
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
Ye R, Dai N, He Q, Guo P, Xiang Y, Zhang Q, Hong Z, Zhang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:962-973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:962-973
Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway.
Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, Bai J, Yang G, Gao N, Yang L, Qi S, Yan R, Liu X, Sun X
Cell death & disease 2018 Sep 20;9(10):946
Cell death & disease 2018 Sep 20;9(10):946
Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
Ayers JI, Riffe CJ, Sorrentino ZA, Diamond J, Fagerli E, Brooks M, Galaleldeen A, Hart PJ, Giasson BI
Journal of virology 2018 Sep 15;92(18)
Journal of virology 2018 Sep 15;92(18)
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H(2)S formation.
Xin D, Chu X, Bai X, Ma W, Yuan H, Qiu J, Liu C, Li T, Zhou X, Chen W, Liu D, Wang Z
Brain, behavior, and immunity 2018 Oct;73:222-234
Brain, behavior, and immunity 2018 Oct;73:222-234
NLRC5 and autophagy combined as possible predictors in patients with endometriosis.
Zhan L, Yao S, Sun S, Su Q, Li J, Wei B
Fertility and sterility 2018 Oct;110(5):949-956
Fertility and sterility 2018 Oct;110(5):949-956
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Wan W, You Z, Zhou L, Xu Y, Peng C, Zhou T, Yi C, Shi Y, Liu W
Molecular cell 2018 Oct 18;72(2):303-315.e6
Molecular cell 2018 Oct 18;72(2):303-315.e6
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
Yang X, Chen XJ, Yang Z, Xi YB, Wang L, Wu Y, Yan YB, Rao Y
Journal of medicinal chemistry 2018 Oct 11;61(19):8693-8706
Journal of medicinal chemistry 2018 Oct 11;61(19):8693-8706
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Cui Y, Zhang Z, Zhang B, Zhao L, Hou C, Zeng Q, Nie J, Yu J, Zhao Y, Gao T, Wang A, Liu H
Toxicology letters 2018 Nov;297:24-33
Toxicology letters 2018 Nov;297:24-33
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Guo S, Liang X, Guo M, Zhang X, Li Z
International journal of biological macromolecules 2018 Nov;119:669-676
International journal of biological macromolecules 2018 Nov;119:669-676
Mutant UBQLN2(P497H) in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Chen T, Huang B, Shi X, Gao L, Huang C
Acta neuropathologica communications 2018 Nov 8;6(1):122
Acta neuropathologica communications 2018 Nov 8;6(1):122
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
Uenaka T, Satake W, Cha PC, Hayakawa H, Baba K, Jiang S, Kobayashi K, Kanagawa M, Okada Y, Mochizuki H, Toda T
Human molecular genetics 2018 Nov 15;27(22):3974-3985
Human molecular genetics 2018 Nov 15;27(22):3974-3985
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury.
Wang Y, Tang C, Cai J, Chen G, Zhang D, Zhang Z, Dong Z
Cell death & disease 2018 Nov 1;9(11):1113
Cell death & disease 2018 Nov 1;9(11):1113
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, Zhou R
Cell death and differentiation 2018 May;25(5):918-934
Cell death and differentiation 2018 May;25(5):918-934
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA
PLoS pathogens 2018 May;14(5):e1007071
PLoS pathogens 2018 May;14(5):e1007071
Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.
Thinon E, Fernandez JP, Molina H, Hang HC
Journal of proteome research 2018 May 4;17(5):1907-1922
Journal of proteome research 2018 May 4;17(5):1907-1922
Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells.
Yang G, Bai Y, Wu X, Sun X, Sun M, Liu X, Yao X, Zhang C, Chu Q, Jiang L, Wang S
Chemico-biological interactions 2018 May 25;288:24-31
Chemico-biological interactions 2018 May 25;288:24-31
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion.
Li Z, Wang G, Feng D, Zu G, Li Y, Shi X, Zhao Y, Jing H, Ning S, Le W, Yao J, Tian X
Cell death & disease 2018 May 1;9(5):483
Cell death & disease 2018 May 1;9(5):483
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33.
Ding L, Ren J, Zhang D, Li Y, Huang X, Hu Q, Wang H, Song Y, Ni Y, Hou Y
Carcinogenesis 2018 Mar 8;39(3):397-406
Carcinogenesis 2018 Mar 8;39(3):397-406
LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
Gao M, Li C, Xu M, Liu Y, Liu S
Toxicology letters 2018 Mar 1;284:195-204
Toxicology letters 2018 Mar 1;284:195-204
TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
Lee Y, Jonson PH, Sarparanta J, Palmio J, Sarkar M, Vihola A, Evilä A, Suominen T, Penttilä S, Savarese M, Johari M, Minot MC, Hilton-Jones D, Maddison P, Chinnery P, Reimann J, Kornblum C, Kraya T, Zierz S, Sue C, Goebel H, Azfer A, Ralston SH, Hackman P, Bucelli RC, Taylor JP, Weihl CC, Udd B
The Journal of clinical investigation 2018 Mar 1;128(3):1164-1177
The Journal of clinical investigation 2018 Mar 1;128(3):1164-1177
Prodigiosin stimulates endoplasmic reticulum stress and induces autophagic cell death in glioblastoma cells.
Cheng SY, Chen NF, Kuo HM, Yang SN, Sung CS, Sung PJ, Wen ZH, Chen WF
Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):314-328
Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):314-328
A tumor-activatable particle with antimetastatic potential in breast cancer via inhibiting the autophagy-dependent disassembly of focal adhesion.
Wang Y, Yin S, Zhang L, Shi K, Tang J, Zhang Z, He Q
Biomaterials 2018 Jun;168:1-9
Biomaterials 2018 Jun;168:1-9
Association of HMGB1, BRCA1 and P62 expression in ovarian cancer and chemotherapy sensitivity.
Li S, Wei Y
Oncology letters 2018 Jun;15(6):9572-9576
Oncology letters 2018 Jun;15(6):9572-9576
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, Song Z, Zhang L, Zhang X, Tian X
Neuropharmacology 2018 Jun;135:151-162
Neuropharmacology 2018 Jun;135:151-162
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, Chen S, Shi A, Chan DC, Song Z
Cell reports 2018 Jun 5;23(10):2989-3005
Cell reports 2018 Jun 5;23(10):2989-3005
Potentiating bacterial cancer therapy using hydroxychloroquine liposomes.
Wang Y, Zhou Z, Chen W, Qin M, Zhang Z, Gong T, Sun X
Journal of controlled release : official journal of the Controlled Release Society 2018 Jun 28;280:39-50
Journal of controlled release : official journal of the Controlled Release Society 2018 Jun 28;280:39-50
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy.
Gong J, Jin J, Zhao L, Li Y, Li Y, He Q
International journal of molecular medicine 2018 Jul;42(1):115-122
International journal of molecular medicine 2018 Jul;42(1):115-122
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress.
Zhang C, Gao J, Li M, Deng Y, Jiang C
Journal of cell science 2018 Jul 26;131(14)
Journal of cell science 2018 Jul 26;131(14)
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice.
Fang X, Ge K, Song C, Ge Y, Zhang J
Biochemical and biophysical research communications 2018 Jul 2;501(4):927-932
Biochemical and biophysical research communications 2018 Jul 2;501(4):927-932
Chronic intermittent hypobaric hypoxia protects vascular endothelium by ameliorating autophagy in metabolic syndrome rats.
Cui F, Guan Y, Guo J, Tian YM, Hu HF, Zhang XJ, Zhang Y
Life sciences 2018 Jul 15;205:145-154
Life sciences 2018 Jul 15;205:145-154
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Hu X, Mei S, Meng W, Xue S, Jiang L, Yang Y, Hui L, Chen Y, Guan MX
Cancer letters 2018 Jul 1;425:1-12
Cancer letters 2018 Jul 1;425:1-12
Pancreatic islet-autonomous effect of arsenic on insulin secretion through endoplasmic reticulum stress-autophagy pathway.
Wu W, Yao X, Jiang L, Zhang Q, Bai J, Qiu T, Yang L, Gao N, Yang G, Liu X, Chen M, Sun X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Jan;111:19-26
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Jan;111:19-26
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Autophagy dysregulation caused by ApoM deficiency plays an important role in liver lipid metabolic disorder.
Zhang X, Zhang P, Gao J, Huang Q
Biochemical and biophysical research communications 2018 Jan 22;495(4):2643-2648
Biochemical and biophysical research communications 2018 Jan 22;495(4):2643-2648
GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.
Xu H, Sun L, Zheng Y, Yu S, Ou-Yang J, Han H, Dai X, Yu X, Li M, Lan Q
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
Biochemical and biophysical research communications 2018 Jan 1;495(1):446-453
MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:1-8
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
He X, Yuan W, Li Z, Hou Y, Liu F, Feng J
Toxicology letters 2018 Feb;283:58-68
Toxicology letters 2018 Feb;283:58-68
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RKA, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D
Zebrafish 2018 Feb;15(1):15-26
Zebrafish 2018 Feb;15(1):15-26
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Xiao Y, Zhou Y, Lu Y, Zhou K, Cai W
Cell death & disease 2018 Feb 7;9(2):160
Cell death & disease 2018 Feb 7;9(2):160
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Li Z, Zhu S, Huang L, Shang M, Yu C, Zhu H, Han D, Huang H, Yu X, Li X
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
Wang W, Chen D, Zhu K
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Journal of experimental & clinical cancer research : CR 2018 Feb 23;37(1):37
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
Li CF, Sun JX, Gao Y, Shi F, Pan YK, Wang YC, Sun XQ
Cell death & disease 2018 Feb 2;9(2):147
Cell death & disease 2018 Feb 2;9(2):147
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.
Du Y, Duan T, Feng Y, Liu Q, Lin M, Cui J, Wang RF
The EMBO journal 2018 Feb 1;37(3):351-366
The EMBO journal 2018 Feb 1;37(3):351-366
Pre-treatment with angiotensin-(1-7) inhibits tumor growth via autophagy by downregulating PI3K/Akt/mTOR signaling in human nasopharyngeal carcinoma xenografts.
Lin YT, Wang HC, Chuang HC, Hsu YC, Yang MY, Chien CY
Journal of molecular medicine (Berlin, Germany) 2018 Dec;96(12):1407-1418
Journal of molecular medicine (Berlin, Germany) 2018 Dec;96(12):1407-1418
Autophagy participates in innate immune defense in lamprey.
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S
Fish & shellfish immunology 2018 Dec;83:416-424
Fish & shellfish immunology 2018 Dec;83:416-424
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Meng X, Liu X, Guo X, Jiang S, Chen T, Hu Z, Liu H, Bai Y, Xue M, Hu R, Sun SC, Liu X, Zhou P, Huang X, Wei L, Yang W, Xu C
Nature 2018 Dec;564(7734):130-135
Nature 2018 Dec;564(7734):130-135
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats.
Huang L, Yuan P, Yu P, Kong Q, Xu Z, Yan X, Shen Y, Yang J, Wan R, Hong K, Tang Y, Hu J
International journal of molecular medicine 2018 Dec;42(6):3278-3290
International journal of molecular medicine 2018 Dec;42(6):3278-3290
Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling.
Dai N, Ye R, He Q, Guo P, Chen H, Zhang Q
Oncology reports 2018 Dec;40(6):3235-3248
Oncology reports 2018 Dec;40(6):3235-3248
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, Wang X, Chen Y, Xie C, Geng S, Wu J, Zhong C, Xu P
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.
Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Ceballos Diaz C, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P
Neurobiology of disease 2018 Dec;120:98-106
Neurobiology of disease 2018 Dec;120:98-106
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Zhang X, Liu H, Hao Y, Xu L, Zhang T, Liu Y, Guo L, Zhu L, Pei Z
Lipids in health and disease 2018 Dec 8;17(1):279
Lipids in health and disease 2018 Dec 8;17(1):279
Attenuating Spinal Cord Injury by Conditioned Medium from Bone Marrow Mesenchymal Stem Cells.
Tsai MJ, Liou DY, Lin YR, Weng CF, Huang MC, Huang WC, Tseng FW, Cheng H
Journal of clinical medicine 2018 Dec 25;8(1)
Journal of clinical medicine 2018 Dec 25;8(1)
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Hsiao CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ, Tsai JW
Journal of cell science 2018 Dec 17;131(24)
Journal of cell science 2018 Dec 17;131(24)
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Wang L, Li X, Chen C
International immunopharmacology 2018 Aug;61:20-28
International immunopharmacology 2018 Aug;61:20-28
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
(-)-Guaiol regulates autophagic cell death depending on mTOR signaling in NSCLC.
Yang X, Zhu J, Wu J, Huang N, Cui Z, Luo Y, Sun F, Pan Q, Li Y, Yang Q
Cancer biology & therapy 2018 Aug 3;19(8):706-714
Cancer biology & therapy 2018 Aug 3;19(8):706-714
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Li J, Zeng C, Zheng B, Liu C, Tang M, Jiang Y, Chang Y, Song W, Wang Y, Yang C
Clinical science (London, England : 1979) 2018 Aug 16;132(15):1645-1667
Clinical science (London, England : 1979) 2018 Aug 16;132(15):1645-1667
Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease.
Huang N, Erie C, Lu ML, Wei J
Molecular and cellular neurosciences 2018 Apr;88:43-52
Molecular and cellular neurosciences 2018 Apr;88:43-52
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G
Journal of pineal research 2018 Apr;64(3)
Journal of pineal research 2018 Apr;64(3)
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Hoyer D, Schneider EK, Velkov T, Xiao X
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, Gao L, Tang D, Jin X, Kong D
Cell death & disease 2018 Apr 1;9(4):419
Cell death & disease 2018 Apr 1;9(4):419
Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.
Qi M, Zhang L, Ma Y, Shuai Y, Li L, Luo K, Liu W, Jin Y
Theranostics 2017;7(18):4498-4516
Theranostics 2017;7(18):4498-4516
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
Wu L, Zhang Q, Dai W, Li S, Feng J, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Gastroenterology research and practice 2017;2017:9724217
Gastroenterology research and practice 2017;2017:9724217
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Dun Y, Liu S, Zhang W, Xie M, Qiu L
Oxidative medicine and cellular longevity 2017;2017:8024857
Oxidative medicine and cellular longevity 2017;2017:8024857
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Li XC, Hu QK, Chen L, Liu SY, Su S, Tao H, Zhang LN, Sun T, He LJ
International journal of medical sciences 2017;14(13):1335-1341
International journal of medical sciences 2017;14(13):1335-1341
RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Muniz-Feliciano L, Doggett TA, Zhou Z, Ferguson TA
Autophagy 2017;13(12):2072-2085
Autophagy 2017;13(12):2072-2085
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, Liu T, Xu S, Fan X, Guo C
Drug design, development and therapy 2017;11:1989-2006
Drug design, development and therapy 2017;11:1989-2006
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Zhou W, Liu L, Xue Y, Zheng J, Liu X, Ma J, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:68
Frontiers in molecular neuroscience 2017;10:68
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Zhao Z, Zhang L, Guo XD, Cao LL, Xue TF, Zhao XJ, Yang DD, Yang J, Ji J, Huang JY, Sun XL
Frontiers in molecular neuroscience 2017;10:293
Frontiers in molecular neuroscience 2017;10:293
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
He Q, Li Z, Wang Y, Hou Y, Li L, Zhao J
International immunopharmacology 2017 Sep;50:208-215
International immunopharmacology 2017 Sep;50:208-215
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Su H, Yang F, Wang Q, Shen Q, Huang J, Peng C, Zhang Y, Wan W, Wong CCL, Sun Q, Wang F, Zhou T, Liu W
Molecular cell 2017 Sep 21;67(6):907-921.e7
Molecular cell 2017 Sep 21;67(6):907-921.e7
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, Hou Y, Wang T
Scientific reports 2017 Sep 18;7(1):11776
Scientific reports 2017 Sep 18;7(1):11776
HMGA2 plays an important role in Cr (VI)-induced autophagy.
Yang F, Zhao L, Mei D, Jiang L, Geng C, Li Q, Yao X, Liu Y, Kong Y, Cao J
International journal of cancer 2017 Sep 1;141(5):986-997
International journal of cancer 2017 Sep 1;141(5):986-997
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Li J, Zhang Q, Li S, Dai W, Feng J, Wu L, Liu T, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells.
Liu N, Jiang L, Sun X, Yao X, Zhai X, Liu X, Wu X, Bai Y, Wang S, Yang G
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:49-56
Toxicology in vitro : an international journal published in association with BIBRA 2017 Oct;44:49-56
An autophagic mechanism is involved in the 6-hydroxydopamine-induced neurotoxicity in vivo.
He X, Yuan W, Li Z, Feng J
Toxicology letters 2017 Oct 5;280:29-40
Toxicology letters 2017 Oct 5;280:29-40
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
Wang M, Wu H, Li S, Xu Z, Li X, Yang Y, Li B, Li Y, Guo J, Chen H
Oncotarget 2017 Oct 27;8(52):89692-89706
Oncotarget 2017 Oct 27;8(52):89692-89706
mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis.
Wan W, You Z, Xu Y, Zhou L, Guan Z, Peng C, Wong CCL, Su H, Zhou T, Xia H, Liu W
Molecular cell 2017 Oct 19;68(2):323-335.e6
Molecular cell 2017 Oct 19;68(2):323-335.e6
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Jin S, Tian S, Luo M, Xie W, Liu T, Duan T, Wu Y, Cui J
Molecular cell 2017 Oct 19;68(2):308-322.e4
Molecular cell 2017 Oct 19;68(2):308-322.e4
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Chen S, Wu DD, Sang XB, Wang LL, Zong ZH, Sun KX, Liu BL, Zhao Y
Cell death & disease 2017 Oct 12;8(10):e3118
Cell death & disease 2017 Oct 12;8(10):e3118
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
Xue TF, Ding X, Ji J, Yan H, Huang JY, Guo XD, Yang J, Sun XL
Journal of pharmacological sciences 2017 Nov;135(3):105-113
Journal of pharmacological sciences 2017 Nov;135(3):105-113
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Prion-like transmission of α-synuclein pathology in the context of an NFL null background.
Rutherford NJ, Brooks M, Riffe CJ, Gorion KM, Howard JK, Dhillon JS, Giasson BI
Neuroscience letters 2017 Nov 20;661:114-120
Neuroscience letters 2017 Nov 20;661:114-120
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Ge W, Zhao K, Wang X, Li H, Yu M, He M, Xue X, Zhu Y, Zhang C, Cheng Y, Jiang S, Hu Y
Cancer cell 2017 Nov 13;32(5):561-573.e6
Cancer cell 2017 Nov 13;32(5):561-573.e6
Synergism and mechanism of Astragaloside IV combined with Ginsenoside Rg1 against autophagic injury of PC12 cells induced by oxygen glucose deprivation/reoxygenation.
Huang XP, Ding H, Yang XQ, Li JX, Tang B, Liu XD, Tang YH, Deng CQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:124-134
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:124-134
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.
Sorrentino ZA, Brooks MMT, Hudson V 3rd, Rutherford NJ, Golde TE, Giasson BI, Chakrabarty P
Molecular neurodegeneration 2017 May 29;12(1):40
Molecular neurodegeneration 2017 May 29;12(1):40
miR-29b contributes to multiple types of muscle atrophy.
Li J, Chan MC, Yu Y, Bei Y, Chen P, Zhou Q, Cheng L, Chen L, Ziegler O, Rowe GC, Das S, Xiao J
Nature communications 2017 May 25;8:15201
Nature communications 2017 May 25;8:15201
BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.
Liu H, Cheng Y, Yang J, Wang W, Fang S, Zhang W, Han B, Zhou Z, Yao H, Chao J, Liao H
Cell death & disease 2017 Mar 9;8(3):e2657
Cell death & disease 2017 Mar 9;8(3):e2657
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
La X, Zhang L, Li Z, Yang P, Wang Y
Oncotarget 2017 Mar 28;8(13):20909-20924
Oncotarget 2017 Mar 28;8(13):20909-20924
Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.
Zhang T, Wang T, Cai P
Molecular medicine reports 2017 Jun;15(6):3566-3574
Molecular medicine reports 2017 Jun;15(6):3566-3574
Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway.
Lin YT, Wang HC, Hsu YC, Cho CL, Yang MY, Chien CY
International journal of molecular sciences 2017 Jun 23;18(7)
International journal of molecular sciences 2017 Jun 23;18(7)
The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells.
Chang H, Li X, Cai Q, Li C, Tian L, Chen J, Xing X, Gan Y, Ouyang W, Yang Z
International journal of molecular medicine 2017 Jul;40(1):182-192
International journal of molecular medicine 2017 Jul;40(1):182-192
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
Sun QZ, Lin GF, Li LL, Jin XT, Huang LY, Zhang G, Yang W, Chen K, Xiang R, Chen C, Wei YQ, Lu GW, Yang SY
Journal of medicinal chemistry 2017 Jul 27;60(14):6337-6352
Journal of medicinal chemistry 2017 Jul 27;60(14):6337-6352
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1-independent autophagy in mice.
Li Y, Wang F, Luo Y
The Journal of surgical research 2017 Jan;207:181-189
The Journal of surgical research 2017 Jan;207:181-189
Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
Koller EJ, Brooks MM, Golde TE, Giasson BI, Chakrabarty P
Molecular neurodegeneration 2017 Jan 3;12(1):1
Molecular neurodegeneration 2017 Jan 3;12(1):1
Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.
Ayers JI, Brooks MM, Rutherford NJ, Howard JK, Sorrentino ZA, Riffe CJ, Giasson BI
Journal of virology 2017 Jan 15;91(2)
Journal of virology 2017 Jan 15;91(2)
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
Zhang H, Li Y, Li L, Liu H, Hu L, Dai Y, Chen J, Xu S, Chen W, Xu X, Xu X
Marine drugs 2017 Feb 17;15(2)
Marine drugs 2017 Feb 17;15(2)
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Wang Y, Wu H, Li Z, Yang P, Li Z
Experimental cell research 2017 Feb 1;351(1):24-35
Experimental cell research 2017 Feb 1;351(1):24-35
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
Liu T, Zhang Z, Yu C, Zeng C, Xu X, Wu G, Huang Z, Li W
British journal of pharmacology 2017 Dec;174(23):4308-4328
British journal of pharmacology 2017 Dec;174(23):4308-4328
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.
Tayebi N, Parisiadou L, Berhe B, Gonzalez AN, Serra-Vinardell J, Tamargo RJ, Maniwang E, Sorrentino Z, Fujiwara H, Grey RJ, Hassan S, Blech-Hermoni YN, Chen C, McGlinchey R, Makariou-Pikis C, Brooks M, Ginns EI, Ory DS, Giasson BI, Sidransky E
Molecular genetics and metabolism 2017 Dec;122(4):198-208
Molecular genetics and metabolism 2017 Dec;122(4):198-208
Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice.
Rutherford NJ, Dhillon JS, Riffe CJ, Howard JK, Brooks M, Giasson BI
Human molecular genetics 2017 Dec 15;26(24):4906-4915
Human molecular genetics 2017 Dec 15;26(24):4906-4915
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y
The Biochemical journal 2017 Aug 2;474(16):2733-2747
The Biochemical journal 2017 Aug 2;474(16):2733-2747
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1.
Yan S, Liu L, Ren F, Gao Q, Xu S, Hou B, Wang Y, Jiang X, Che Y
Cell death & disease 2017 Aug 10;8(8):e2988
Cell death & disease 2017 Aug 10;8(8):e2988
Systematic Characterization of Autophagy in Gestational Diabetes Mellitus.
Ji L, Chen Z, Xu Y, Xiong G, Liu R, Wu C, Hu H, Wang L
Endocrinology 2017 Aug 1;158(8):2522-2532
Endocrinology 2017 Aug 1;158(8):2522-2532
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Zhang L, Li J, Ma J, Chen X, Chen K, Jiang Z, Zong L, Yu S, Li X, Xu Q, Lei J, Duan W, Li W, Shan T, Ma Q, Shen X
Oxidative medicine and cellular longevity 2016;2016:3897250
Oxidative medicine and cellular longevity 2016;2016:3897250
Regulation of Autophagy-Related Protein and Cell Differentiation by High Mobility Group Box 1 Protein in Adipocytes.
Feng H, Yu L, Zhang G, Liu G, Yang C, Wang H, Song X
Mediators of inflammation 2016;2016:1936386
Mediators of inflammation 2016;2016:1936386
Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.
Gao J, Li M, Qin S, Zhang T, Jiang S, Hu Y, Deng Y, Zhang C, You D, Li H, Mu D, Zhang Z, Jiang C
Autophagy 2016;12(4):632-47
Autophagy 2016;12(4):632-47
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Li J, Chen K, Li S, Feng J, Liu T, Wang F, Zhang R, Xu S, Zhou Y, Zhou S, Xia Y, Lu J, Zhou Y, Guo C
Drug design, development and therapy 2016;10:619-30
Drug design, development and therapy 2016;10:619-30
Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment.
Qin L, Xu T, Xia L, Wang X, Zhang X, Zhang X, Zhu Z, Zhong S, Wang C, Shen Z
Drug design, development and therapy 2016;10:1035-45
Drug design, development and therapy 2016;10:1035-45
Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages.
Liu E, Lopez Corcino Y, Portillo JA, Miao Y, Subauste CS
Infection and immunity 2016 Sep;84(9):2616-26
Infection and immunity 2016 Sep;84(9):2616-26
Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition.
Ju JS, Jeon SI, Park JY, Lee JY, Lee SC, Cho KJ, Jeong JM
The journal of physiological sciences : JPS 2016 Sep;66(5):417-30
The journal of physiological sciences : JPS 2016 Sep;66(5):417-30
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Dai C, Tang S, Velkov T, Xiao X
Molecular neurobiology 2016 Sep;53(7):4685-700
Molecular neurobiology 2016 Sep;53(7):4685-700
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Zhang Y, Shen K, Bai Y, Lv X, Huang R, Zhang W, Chao J, Nguyen LK, Hua J, Gan G, Hu G, Yao H
Autophagy 2016 Sep;12(9):1538-59
Autophagy 2016 Sep;12(9):1538-59
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Guo YJ, Dong SY, Cui XX, Feng Y, Liu T, Yin M, Kuo SH, Tan EK, Zhao WJ, Wu YC
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Sun R, Shen S, Zhang YJ, Xu CF, Cao ZT, Wen LP, Wang J
Biomaterials 2016 Oct;103:44-55
Biomaterials 2016 Oct;103:44-55
Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.
Breid S, Bernis ME, Babila JT, Garza MC, Wille H, Tamgüney G
Journal of virology 2016 Oct 15;90(20):9182-93
Journal of virology 2016 Oct 15;90(20):9182-93
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Wang HS, Pei F, Chen Z, Zhang L
Journal of dental research 2016 Jun;95(6):697-703
Journal of dental research 2016 Jun;95(6):697-703
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Wang K, Zhang C, Bao J, Jia X, Liang Y, Wang X, Chen M, Su H, Li P, Wan JB, He C
Scientific reports 2016 Jun 6;6:26064
Scientific reports 2016 Jun 6;6:26064
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin.
Wang Y, Shi K, Zhang L, Hu G, Wan J, Tang J, Yin S, Duan J, Qin M, Wang N, Xie D, Gao X, Gao H, Zhang Z, He Q
Autophagy 2016 Jun 2;12(6):949-62
Autophagy 2016 Jun 2;12(6):949-62
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Su C, Shi Q, Song X, Fu J, Liu Z, Wang Y, Wang Y, Xia X, Song E, Song Y
Toxicology 2016 Jul 1;363-364:48-57
Toxicology 2016 Jul 1;363-364:48-57
Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cells.
Peng WX, Xiong EM, Ge L, Wan YY, Zhang CL, Du FY, Xu M, Bhat RA, Jin J, Gong AH
Experimental cell research 2016 Jan 1;340(1):62-70
Experimental cell research 2016 Jan 1;340(1):62-70
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
Yao J, Ma C, Gao W, Liang J, Liu C, Yang H, Yan Q, Wen Q
Oncology reports 2016 Dec;36(6):3363-3370
Oncology reports 2016 Dec;36(6):3363-3370
β-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1-dependent autophagy.
Deng M, Huang L, Ning B, Wang N, Zhang Q, Zhu C, Fang Y
Brain research 2016 Dec 1;1652:188-194
Brain research 2016 Dec 1;1652:188-194
Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus.
Li X, Liu F, Zhang X, Shi G, Ren J, Ji J, Ding L, Fan H, Dou H, Hou Y
Cell death & disease 2016 Aug 18;7(8):e2341
Cell death & disease 2016 Aug 18;7(8):e2341
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy.
Liu T, Tang Q, Liu K, Xie W, Liu X, Wang H, Wang RF, Cui J
Cell reports 2016 Aug 16;16(7):1988-2002
Cell reports 2016 Aug 16;16(7):1988-2002
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Liu X, Chen L, Ge J, Yan C, Huang Z, Hu J, Wen C, Li M, Huang D, Qiu Y, Hao H, Yuan R, Lei J, Yu X, Shao J
Cancer research 2016 Aug 15;76(16):4897-907
Cancer research 2016 Aug 15;76(16):4897-907
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Webster CP, Smith EF, Bauer CS, Moller A, Hautbergue GM, Ferraiuolo L, Myszczynska MA, Higginbottom A, Walsh MJ, Whitworth AJ, Kaspar BK, Meyer K, Shaw PJ, Grierson AJ, De Vos KJ
The EMBO journal 2016 Aug 1;35(15):1656-76
The EMBO journal 2016 Aug 1;35(15):1656-76
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Sun L, Liu N, Liu SS, Xia WY, Liu MY, Li LF, Gao JX
American journal of cancer research 2015;5(9):2626-42
American journal of cancer research 2015;5(9):2626-42
Autophagy protects renal tubular cells against ischemia / reperfusion injury in a time-dependent manner.
Guan X, Qian Y, Shen Y, Zhang L, Du Y, Dai H, Qian J, Yan Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(1):285-98
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(1):285-98
Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice.
Zhao XG, Sun RJ, Yang XY, Liu DY, Lei DP, Jin T, Pan XL
PloS one 2015;10(4):e0126147
PloS one 2015;10(4):e0126147
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.
Brun T, Li N, Jourdain AA, Gaudet P, Duhamel D, Meyer J, Bosco D, Maechler P
Human molecular genetics 2015 Sep 15;24(18):5270-84
Human molecular genetics 2015 Sep 15;24(18):5270-84
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.
Hunt JB Jr, Nash KR, Placides D, Moran P, Selenica ML, Abuqalbeen F, Ratnasamy K, Slouha N, Rodriguez-Ospina S, Savlia M, Ranaweera Y, Reid P, Dickey CA, Uricia R, Yang CG, Sandusky LA, Gordon MN, Morgan D, Lee DC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Nov 4;35(44):14842-60
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Nov 4;35(44):14842-60
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Li J, Wang F, Xia Y, Dai W, Chen K, Li S, Liu T, Zheng Y, Wang J, Lu W, Zhou Y, Yin Q, Lu J, Zhou Y, Guo C
Marine drugs 2015 May 27;13(6):3368-87
Marine drugs 2015 May 27;13(6):3368-87
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Yang R, Zhang M, Gustafson AR, Wang E, Cole MP, Tooley CE, Cheng A
Bioscience reports 2015 May 1;35(3)
Bioscience reports 2015 May 1;35(3)
Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells.
Liu YN, Wang YX, Liu XF, Jiang LP, Yang G, Sun XC, Geng CY, Li QJ, Chen M, Yao XF
Toxicon : official journal of the International Society on Toxinology 2015 Mar;95:30-7
Toxicon : official journal of the International Society on Toxinology 2015 Mar;95:30-7
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Yue M, Hinkle KM, Davies P, Trushina E, Fiesel FC, Christenson TA, Schroeder AS, Zhang L, Bowles E, Behrouz B, Lincoln SJ, Beevers JE, Milnerwood AJ, Kurti A, McLean PJ, Fryer JD, Springer W, Dickson DW, Farrer MJ, Melrose HL
Neurobiology of disease 2015 Jun;78:172-95
Neurobiology of disease 2015 Jun;78:172-95
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
Ceballos-Diaz C, Rosario AM, Park HJ, Chakrabarty P, Sacino A, Cruz PE, Siemienski Z, Lara N, Moran C, Ravelo N, Golde TE, McFarland NR
Molecular neurodegeneration 2015 Jul 8;10:25
Molecular neurodegeneration 2015 Jul 8;10:25
Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.
Rutherford NJ, Sacino AN, Brooks M, Ceballos-Diaz C, Ladd TB, Howard JK, Golde TE, Giasson BI
Molecular neurodegeneration 2015 Jul 30;10:32
Molecular neurodegeneration 2015 Jul 30;10:32
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux.
Wang Y, Tai X, Zhang L, Liu Y, Gao H, Chen J, Shi K, Zhang Q, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2015 Feb 10;199:17-28
Journal of controlled release : official journal of the Controlled Release Society 2015 Feb 10;199:17-28
Induction of autophagy improves embryo viability in cloned mouse embryos.
Shen X, Zhang N, Wang Z, Bai G, Zheng Z, Gu Y, Wu Y, Liu H, Zhou D, Lei L
Scientific reports 2015 Dec 8;5:17829
Scientific reports 2015 Dec 8;5:17829
Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach.
Narayan M, Seeley KW, Jinwal UK
Journal of ethnopharmacology 2015 Dec 4;175:86-92
Journal of ethnopharmacology 2015 Dec 4;175:86-92
Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease.
Erie C, Sacino M, Houle L, Lu ML, Wei J
The European journal of neuroscience 2015 Aug;42(3):1941-51
The European journal of neuroscience 2015 Aug;42(3):1941-51
SQSTM1 splice site mutation in distal myopathy with rimmed vacuoles.
Bucelli RC, Arhzaouy K, Pestronk A, Pittman SK, Rojas L, Sue CM, Evilä A, Hackman P, Udd B, Harms MB, Weihl CC
Neurology 2015 Aug 25;85(8):665-74
Neurology 2015 Aug 25;85(8):665-74
Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG(2) cells to epirubicin.
Peng W, DU T, Zhang Z, DU F, Jin J, Gong A
Experimental and therapeutic medicine 2015 Apr;9(4):1271-1276
Experimental and therapeutic medicine 2015 Apr;9(4):1271-1276
Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis.
Weihl CC, Baloh RH, Lee Y, Chou TF, Pittman SK, Lopate G, Allred P, Jockel-Balsarotti J, Pestronk A, Harms MB
Neuromuscular disorders : NMD 2015 Apr;25(4):289-96
Neuromuscular disorders : NMD 2015 Apr;25(4):289-96
Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma.
Bao LJ, Jaramillo MC, Zhang ZB, Zheng YX, Yao M, Zhang DD, Yi XF
International journal of clinical and experimental pathology 2014;7(4):1502-13
International journal of clinical and experimental pathology 2014;7(4):1502-13
Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.
Sacino AN, Brooks M, McKinney AB, Thomas MA, Shaw G, Golde TE, Giasson BI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 10;34(37):12368-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 10;34(37):12368-78
A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.
Gonzalez MA, Feely SM, Speziani F, Strickland AV, Danzi M, Bacon C, Lee Y, Chou TF, Blanton SH, Weihl CC, Zuchner S, Shy ME
Brain : a journal of neurology 2014 Nov;137(Pt 11):2897-902
Brain : a journal of neurology 2014 Nov;137(Pt 11):2897-902
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
Yao XF, Cao J, Xu LM, Sun XC, Kang J, Yang G, Jiang LP, Geng CY, Gao CZ, Zhong LF, Ma YF
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
Sacino AN, Brooks M, Thomas MA, McKinney AB, McGarvey NH, Rutherford NJ, Ceballos-Diaz C, Robertson J, Golde TE, Giasson BI
Acta neuropathologica 2014 May;127(5):645-65
Acta neuropathologica 2014 May;127(5):645-65
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10732-7
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10732-7
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Liang JX, Ning Z, Gao W, Ling J, Wang AM, Luo HF, Liang Y, Yan Q, Wang ZY
Oncology reports 2014 Dec;32(6):2726-34
Oncology reports 2014 Dec;32(6):2726-34
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.
Fiesel FC, Moussaud-Lamodière EL, Ando M, Springer W
Journal of cell science 2014 Aug 15;127(Pt 16):3488-504
Journal of cell science 2014 Aug 15;127(Pt 16):3488-504
mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Ching JK, Elizabeth SV, Ju JS, Lusk C, Pittman SK, Weihl CC
Human molecular genetics 2013 Mar 15;22(6):1167-79
Human molecular genetics 2013 Mar 15;22(6):1167-79
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.
Sacino AN, Brooks M, McGarvey NH, McKinney AB, Thomas MA, Levites Y, Ran Y, Golde TE, Giasson BI
Acta neuropathologica communications 2013 Jul 17;1:38
Acta neuropathologica communications 2013 Jul 17;1:38
Increased autophagy accelerates colchicine-induced muscle toxicity.
Ching JK, Ju JS, Pittman SK, Margeta M, Weihl CC
Autophagy 2013 Dec;9(12):2115-25
Autophagy 2013 Dec;9(12):2115-25
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 18420-1-AP(SQSTM1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SQSTM1 antibody 18420-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-P62;SQSTM1 (IP:18420-1-AP, 3ug; Detection:18420-1-AP 1:2000) with HEK-293 cells lysate 1300ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 18420-1-AP(SQSTM1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
