Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AP0771 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- SQSTM1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human SQSTM1.
- Description
- The chronic focal skeletal disorder, Paget£ªs disease of bone, affects 2-3% of the population over the age of 60 years. Paget£ªs disease is characterized by increased bone resorption by osteoclasts, followed by abundant new bone formation that is of poor quality. The disease leads to several complications including bone pain and deformities, as well as fissures and fractures. Mutations in the ubiquitin-associated (UBA) domain of the Sequestosome 1 protein (SQSTM1), also designated p62 or ZIP, commonly cause Paget£ªs disease since the UBA is necessary for aggregate sequestration and cell survival. The SQSTM1-L1 gene product, also known as LOC647259, has been provisionally designated SQSTM1-L1 pending further characterization.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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