AP0771

antibody from Bioworld Technology, Inc
Targeting: SQSTM1 A170, OSIL, p60, p62, p62B, PDB3
Provider product page for AP0771
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
AP0771 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SQSTM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human SQSTM1.
Description
The chronic focal skeletal disorder, Paget£ªs disease of bone, affects 2-3% of the population over the age of 60 years. Paget£ªs disease is characterized by increased bone resorption by osteoclasts, followed by abundant new bone formation that is of poor quality. The disease leads to several complications including bone pain and deformities, as well as fissures and fractures. Mutations in the ubiquitin-associated (UBA) domain of the Sequestosome 1 protein (SQSTM1), also designated p62 or ZIP, commonly cause Paget£ªs disease since the UBA is necessary for aggregate sequestration and cell survival. The SQSTM1-L1 gene product, also known as LOC647259, has been provisionally designated SQSTM1-L1 pending further characterization.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SQSTM1 protein structure - AP0771 shown in red.