84826-1-RR

antibody from Proteintech Group

Targeting: SQSTM1 A170, OSIL, p60, p62, p62B, PDB3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

84826-1-RR

Provider

Proteintech Group

Product name

P62/SQSTM1 monoclonal antibody

Antibody type

Recombinant

Description

P62/SQSTM1 monoclonal antibody (Catalog no. 84826-1-RR) is a rabbit recombinant antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, IHC, IF/ICC, FC (Intra), IP, ELISA

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

241992C4

References

Submitted references

IL-22 inhibits ferroptosis and attenuates ischemia-reperfusion-induced acute kidney injury: Association with activation of the P62-Keap1-Nrf2 signaling pathway.

Zhang L, Luo F, Chai Y, Sun L, Wang X, Yin L, Luo C
PloS one 2026;21(2):e0342335

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PYCR1 Downregulation Induces Autophagy Dependent Apoptosis Through Inhibiting PI3K/AKT/mTOR Axis in Human Hepatocellular Carcinoma Cells.

Zhang J, Hou Y, Jin X, Gu B, Wu W
Analytical cellular pathology (Amsterdam) 2026;2026(1):e3662809

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Reproductive toxicity mechanisms of PNMC: Evidence from mitochondrial dysfunction and hormone synthesis disruption in the KGN cells.

Xie J, Pan Z, Du Y, Li K, Liu Y, Weng Q, Zhang H
Reproductive toxicology (Elmsford, N.Y.) 2026 May;142:109223

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Gentiana szechenyii Kanitz Compounds Regulate Lipopolysaccharide-Induced Inflammation and Mitochondrial Autophagy Via the Toll-Like Receptor 4-Nuclear Factor Kappa B Pathway.

Zhang H, Zhang Z, Hu J, Li Y, Nan X, Yang F
Chemistry & biodiversity 2026 Mar;23(3):e03838

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Insights on the enhanced wound healing potential of russelioside B isolated from Caralluma quadrangula via modulation of AMPK/Beclin-1 and P-62 autophagy pathway.

Ali MM, Al-Mokaddem AK, Abdel-Sattar E, El-Shiekh RA, Al-Hawshabi OSS, Farag MM, Aljuaydi SH, Shaheed IB
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108008

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Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.

Wu W, Chen Z, Xu Y, Xie X, Tan A, Hu M, Xu D, Lv X, Chen W, Zhou J, Zhu Y, Ma H
Free radical biology & medicine 2026 Jun;249:589-602

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Butyrate-Modified Hyaluronic Acid Ameliorates MPTP-Induced Parkinson's Disease via Modulating PINK1/Parkin-Involved Mitophagy and Intestinal Flora.

Sun Y, Cui L, Peng W, Chen R, Guan X, Liu J
Biomacromolecules 2026 Jan 12;27(1):134-149

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Integrated multi-omics and machine learning elucidate the pathogenic role of mitophagy in osteoarthritis and identify novel therapeutic strategies.

Dong Q, Huang H, Feng Y, Chao L, Wu Z, Zha Z, Li R, Chen J
International immunopharmacology 2026 Jan 1;168(Pt 2):115916

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Lipophagy Dynamics in Hyperlipidemia Model ICR Mice Across Different High-Fat-Diet Feeding Durations.

Xue S, Guo X, Wang Q, Chen X, Yang J, Zhou Y, Zhang Y, Niu W
International journal of molecular sciences 2026 Feb 5;27(3)

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Icaritin eliminates tumor-associated macrophages via STX16-dependent extracellular vesicle delivery of autophagosomes from hepatocellular carcinoma cells.

Zheng X, Qu W, Xun C, Zhang C, Li Y, Xu X, Gao Y, Gu Y, Yang Z, Huang X, Qian J
Journal of experimental & clinical cancer research : CR 2026 Feb 23;45(1)

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Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.

You T, Dai B, Ding X, He Z, Peng J, Tao S, Ye L, Song T, Fan Z, Chen N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985

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Targeting Fgr-STAT3 Mediated Autophagy Inhibition in the Spinal Cord Alleviates Neuropathic Pain in Rats.

He L, Zhang Y, Yang C, Huang Z, Zou K, Deng Q, Zhang J, Mulati M, Sun B, Guo Q, Huang C
Neuroscience bulletin 2026 Apr 9;

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Development of an efficient mice model of cancer-associated cardiac cachexia.

Xiong S, Zheng H, Wu T, Tan J, Huang T, Shen C, Ji Y, Liu M, Wan J, Cai W
Animal models and experimental medicine 2025 Nov;8(11):1960-1970

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Carvedilol Confers Neuroprotective Activity Through Modulating Ferroptosis Key Players and PINK1/PARKIN Mediated Mitophagy in an Experimental Parkinson's Rat Model.

Abuelezz NZ, Ahmed MK, Abd El Aziz AE, El Sayed NS
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70607

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Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux.

Bian WH, Wang SH, Kang ZC, Xu Y, Li YN, Yang MZ, Yang JH, Liu JY, Cheng YL, Chang D, Xie X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157357

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MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia-Reperfusion Injury.

Li H, Xie X, Zhang Y, Han X, Shi T, Li J, Chen W, Wei Q, Pan H, Xu S, Chen Q, Yin L, Qin C
Pharmaceutics 2025 Nov 16;17(11)

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Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.

Wu Y, Zhou H, Liu H, Hu J, Sun Y, Yan W, Tong C, Kong Y, Liu B
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320

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Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis.

Qin Z, Xie L, Wang Y, Zhang N, Bi H, Song M, Xu C
Metabolites 2025 Jun 5;15(6)

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5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.

Xu N, Huang J, Wang Y, Liu Y, Jiang Y, Zhou W, Sheng J, Zhang L
Acta biochimica et biophysica Sinica 2025 Jun 23;58(2):290-302

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Canagliflozin Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease via Mitochondrial Protection and Enhanced Mitophagy.

Lu M, Zhao Y, Liu Z, Zhang Y, Liu J
Hepatology research : the official journal of the Japan Society of Hepatology 2025 Dec;55(12):1598-1609

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m6A Methylation-Induced Autophagy Impairment by TFEB Regulation in SOD1-G93A ALS Cell Model.

An D, Wu Y, Han J, Fang P, Bu Y, Ji G, Deng J, Song X
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2025 Dec;198(8):221-229

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Regulation of autophagy by oncogene DJ1 via the JNK signaling pathway in human ovarian cancer cells.

Zhao XM, Wang K, Wang Z, Xie D, Liu H, Li P, Wang WM
Journal of ovarian research 2025 Dec 27;19(1):30

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Identifying Key Genes of Proanthocyanidin Intervention in Fluoride-Induced Liver Injury: Integrated Molecular Docking and Experimental Validation.

Wu Z, Xiao M, Gong Z, Wang B, Zhao W, Guo Y, Yang L
Genes 2025 Aug 31;16(9)

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Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.

Hong R, Shi Y, Fan Z, Gao Y, Chen H, Pan C
Toxicology 2024 Dec;509:153996