MA5-24656

antibody from Invitrogen Antibodies

Targeting: LAMA2 LAMM

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-24656

Provider

Invitrogen Antibodies

Product name

Laminin alpha-2 Monoclonal Antibody (CL3450)

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: DKLKPIKELE DNLKKNISEI KELINQARKQ ANSIKVSVSS GGDCIRTYKP EIKKGSYNNI VVNVKTAVAD NLLFYLGSAK FIDFLAIEMR KGKVSFLWDV GSGVGRVEYP DLTIDDSYWY RIVASRTGRN GT Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%. Binds to an epitope located within the peptide sequence DKLKPIKELEDNLKK as determined by overlapping synthetic peptides.

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

CL3450

Vial size

100 µL

Concentration

1.0 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in human placenta using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows moderate positivity in basement membrane of trophoblastic cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in rat stomach using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows strong positivity in basement membrane of glandular cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in mouse heart muscle using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows strong membranous positivity in cardiomyocytes.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in human heart muscle and tonsil tissues using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656). Corresponding LAMA2 RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in human heart muscle using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows strong membranous positivity in cardiomyocytes.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in human cerebral cortex using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows moderate positivity in blood vessels.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in human tonsil using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows no positivity in lymphoid cells as expected.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Laminin alpha-2 in rat heart muscle using Laminin alpha-2 Monoclonal Antibody (CL3450) (Product # MA5-24656) shows strong membranous positivity in cardiomyocytes.