Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations [0]
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- Product number
- ALX-804-190-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-190-C100, RRID:AB_2051764
- Product name
- Laminin-2 (_-2-chain) monoclonal antibody (4H8-2)
- Antibody type
- Monoclonal
- Antigen
- Purified from natural sources
- Description
- Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.
- Reactivity
- Human, Mouse
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 4H8-2
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
Submitted references MicroRNA-26a induced by hypoxia targets HDAC6 in myogenic differentiation of embryonic stem cells.
Dystroglycan does not contribute significantly to kidney development or function, in health or after injury.
Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells.
Maintenance of glomerular filtration barrier integrity requires laminin alpha5.
Hematopoietic contribution to skeletal muscle regeneration in acid alpha-glucosidase knockout mice.
A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination.
Lung development in laminin gamma2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation.
Laminin alpha2 is essential for odontoblast differentiation regulating dentin sialoprotein expression.
Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization.
Skeletal muscle engraftment potential of adult mouse skin side population cells.
Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice.
Characterization of bone marrow laminins and identification of alpha5-containing laminins as adhesive proteins for multipotent hematopoietic FDCP-Mix cells.
Mild congenital muscular dystrophy in two patients with an internally deleted laminin alpha2-chain.
Diagnosis of merosin (laminin-2) deficient congenital muscular dystrophy by skin biopsy.
Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.
Lee SW, Yang J, Kim SY, Jeong HK, Lee J, Kim WJ, Lee EJ, Kim HS
Nucleic acids research 2015 Feb 27;43(4):2057-73
Nucleic acids research 2015 Feb 27;43(4):2057-73
Dystroglycan does not contribute significantly to kidney development or function, in health or after injury.
Jarad G, Pippin JW, Shankland SJ, Kreidberg JA, Miner JH
American journal of physiology. Renal physiology 2011 Mar;300(3):F811-20
American journal of physiology. Renal physiology 2011 Mar;300(3):F811-20
Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells.
Mizuno Y, Chang H, Umeda K, Niwa A, Iwasa T, Awaya T, Fukada S, Yamamoto H, Yamanaka S, Nakahata T, Heike T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Jul;24(7):2245-53
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Jul;24(7):2245-53
Maintenance of glomerular filtration barrier integrity requires laminin alpha5.
Goldberg S, Adair-Kirk TL, Senior RM, Miner JH
Journal of the American Society of Nephrology : JASN 2010 Apr;21(4):579-86
Journal of the American Society of Nephrology : JASN 2010 Apr;21(4):579-86
Hematopoietic contribution to skeletal muscle regeneration in acid alpha-glucosidase knockout mice.
Mori J, Ishihara Y, Matsuo K, Nakajima H, Terada N, Kosaka K, Kizaki Z, Sugimoto T
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008 Sep;56(9):811-7
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008 Sep;56(9):811-7
A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination.
Patton BL, Wang B, Tarumi YS, Seburn KL, Burgess RW
Journal of cell science 2008 May 15;121(Pt 10):1593-604
Journal of cell science 2008 May 15;121(Pt 10):1593-604
Lung development in laminin gamma2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation.
Nguyen NM, Pulkkinen L, Schlueter JA, Meneguzzi G, Uitto J, Senior RM
Respiratory research 2006 Feb 16;7:28
Respiratory research 2006 Feb 16;7:28
Laminin alpha2 is essential for odontoblast differentiation regulating dentin sialoprotein expression.
Yuasa K, Fukumoto S, Kamasaki Y, Yamada A, Fukumoto E, Kanaoka K, Saito K, Harada H, Arikawa-Hirasawa E, Miyagoe-Suzuki Y, Takeda S, Okamoto K, Kato Y, Fujiwara T
The Journal of biological chemistry 2004 Mar 12;279(11):10286-92
The Journal of biological chemistry 2004 Mar 12;279(11):10286-92
Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization.
Miner JH, Li C, Patton BL
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2004 Feb;52(2):153-6
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2004 Feb;52(2):153-6
Skeletal muscle engraftment potential of adult mouse skin side population cells.
Montanaro F, Liadaki K, Volinski J, Flint A, Kunkel LM
Proceedings of the National Academy of Sciences of the United States of America 2003 Aug 5;100(16):9336-41
Proceedings of the National Academy of Sciences of the United States of America 2003 Aug 5;100(16):9336-41
Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice.
Araishi K, Sasaoka T, Imamura M, Noguchi S, Hama H, Wakabayashi E, Yoshida M, Hori T, Ozawa E
Human molecular genetics 1999 Sep;8(9):1589-98
Human molecular genetics 1999 Sep;8(9):1589-98
Characterization of bone marrow laminins and identification of alpha5-containing laminins as adhesive proteins for multipotent hematopoietic FDCP-Mix cells.
Gu Y, Sorokin L, Durbeej M, Hjalt T, Jönsson JI, Ekblom M
Blood 1999 Apr 15;93(8):2533-42
Blood 1999 Apr 15;93(8):2533-42
Mild congenital muscular dystrophy in two patients with an internally deleted laminin alpha2-chain.
Allamand V, Sunada Y, Salih MA, Straub V, Ozo CO, Al-Turaiki MH, Akbar M, Kolo T, Colognato H, Zhang X, Sorokin LM, Yurchenco PD, Tryggvason K, Campbell KP
Human molecular genetics 1997 May;6(5):747-52
Human molecular genetics 1997 May;6(5):747-52
Diagnosis of merosin (laminin-2) deficient congenital muscular dystrophy by skin biopsy.
Sewry CA, Philpot J, Sorokin LM, Wilson LA, Naom I, Goodwin F, D'Alessandro M, Dubowitz V, Muntoni F
Lancet (London, England) 1996 Mar 2;347(9001):582-4
Lancet (London, England) 1996 Mar 2;347(9001):582-4
Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.
Schuler F, Sorokin LM
Journal of cell science 1995 Dec;108 ( Pt 12):3795-805
Journal of cell science 1995 Dec;108 ( Pt 12):3795-805
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