Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- 916606 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#916606, RRID:AB_2565820
- Product name
- Purified anti-Podoplanin (Lymphatic Endothelial Marker)
- Antibody type
- Monoclonal
- Antigen
- M2A protein derived from human germ cell tumors.
- Description
- Podoplanin is expressed by a variety of normal cells, which include breast and prostate myopepithelial cells, follicular dendritic cells, basal keratinocytes of the skin and cervix (focal), type I pneumocytes, ependymal cells, and fetal cerebral germinal matrix cells. Podoplanin is a marker of lymphatic differentiation because it is expressed by normal human lymphatic endothelium, but not by vascular endothelium. It is diagnostically a useful marker for the evaluation of a variety of neoplasms, including Kaposi sarcoma mesothelioma, testicular germ cell tumors, and cutanneous sebaceous neoplasms.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- D2-40
- Vial size
- 100 µg
- Concentration
- 1.0 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Staining of Clone D2-40 on formalin fixed paraffin embedded human colon tissue at 1 µg/ml.