Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- 337001 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#337001, RRID:AB_1595616
- Product name
- Purified anti-Human Podoplanin
- Antibody type
- Monoclonal
- Antigen
- Podoplanin
- Description
- Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.
Chyou S, Benahmed F, Chen J, Kumar V, Tian S, Lipp M, Lu TT
Journal of immunology (Baltimore, Md. : 1950) 2011 Dec 1;187(11):5558-67
Journal of immunology (Baltimore, Md. : 1950) 2011 Dec 1;187(11):5558-67
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