337002

antibody from BioLegend

Targeting: PDPN aggrus, Gp38, GP40, PA2.26, T1A-2

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

337002

Provider

BioLegend

Proper citation

BioLegend Cat#337002, RRID:AB_1595511

Product name

Purified anti-Human Podoplanin

Antibody type

Monoclonal

Antigen

Podoplanin

Description

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

Reactivity

Human

Host

Rat

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C.

References

Submitted references

Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.

Chyou S, Benahmed F, Chen J, Kumar V, Tian S, Lipp M, Lu TT
Journal of immunology (Baltimore, Md. : 1950) 2011 Dec 1;187(11):5558-67