11629-1-AP

antibody from Proteintech Group

Targeting: PDPN aggrus, Gp38, GP40, PA2.26, T1A-2

Provider product page for 11629-1-AP

Western blot

ELISA

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [23]
Comments [0]
Validations
Immunohistochemistry [2]

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Product number: 11629-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11629-1-AP, RRID:AB_2162067
Product name: Podoplanin antibody
Antibody type: Polyclonal
Description: Podoplanin antibody (Cat. #11629-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

PDPN protein structure - 11629-1-AP shown in red.

Submitted references SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.

Gao GF, Ruan ZH, Zhang SB, He S, Li YQ, Lyu JL, Liu Y, Tan XL, Wang YJ, Liu ZW, Lv GZ, Chen G, Yu JH, Wei PP, Zhao JF, Sun ZT, Zhao Z, Shi Y, Liao W, Chen SW, Zhang N, Kuang DM, Guan XY, Peng RJ, Cai MY, Yao K, Bian XW, Ding PR, Luo CL, Bei JX
Gut 2026 Feb 10;

Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis.

Kong L, Chen H, Zhang H, Zhang X, Chen J, Nie Y, Su Z, Lin L
Journal of inflammation research 2025;18:17129-17142

Targeting PDPN enhances antitumor T-cell activity by disrupting β-catenin-mediated PD-L1 expression in melanoma.

Feng C, Liu Y, Zhong X, Wei Z, Cui H, Yi J
Frontiers in immunology 2025;16:1692864

Exploring Core Genes Involved in Ischemic Stroke and the Therapeutic Potential of Hyperbaric Oxygen: Insights from Transcriptomic Analysis.

Bao Y, Guo X, Wang J, Kang J, Ma R, Cheng X, Ma Y, Niu Y, Zhang W, Li X
Neuromolecular medicine 2025 Jul 26;27(1):54

Dihydrotanshinone I improves cardiac function by promoting lymphangiogenesis after myocardial ischemia-reperfusion injury.

Wang YC, Zhu Y, Meng WT, Zheng Y, Guan XQ, Shao CL, Li XY, Hu D, Wang MZ, Guo HD
European journal of pharmacology 2025 Feb 15;989:177245

Structure and thickness of Glisson's capsule differ considerably on the liver surface in mammalian species.

Uchida H, Aihara N, Morimura T, Matsumoto S, Hasegawa D, Ichiki T, Okamura E, Muto M, Sugahara G, Miki T, Ema M, Watanabe K, Kamiie J, Asahina K
Anatomical record (Hoboken, N.J. : 2007) 2025 Dec;308(12):3283-3296

Acidosis regulates immune progression in rheumatoid arthritis by promoting the expression of cytokines and co-stimulatory molecules in synovial fibroblasts.

Qian X, Zai Z, Tao Y, Lv H, Hao M, Zhang L, Zhang X, Xu Y, Zhang Y, Chen F
Molecular medicine (Cambridge, Mass.) 2025 Apr 15;31(1):136

Podoplanin immunoexpression in odontogenic lesions: a systematic review, meta-analysis, and integrated bioinformatic analysis.

Alarcón-Sánchez MA, Luna-Bonilla G, Romero-Servin S, Heboyan A
Diagnostic pathology 2024 Aug 24;19(1):115

Liu Z, Zeinalzadeh Z, Huang T, Han Y, Peng L, Wang D, Zhou Z, Ousmane D, Wang J
Translational oncology 2024 Apr;42:101896

Microgel-based carriers enhance skeletal stem cell reprogramming towards immunomodulatory phenotype in osteoarthritic therapy.

Li PL, Chen DF, Li XT, Hao RC, Zhao ZD, Li ZL, Yin BF, Tang J, Luo YW, Wu CT, Nie JJ, Zhu H
Bioactive materials 2024 Apr;34:204-220

Refractory kaposiform lymphangiomatosis relieved by splenectomy.

Lan Y, Zhou J, Qiu T, Gong X, Ji Y
Frontiers in pediatrics 2023;11:1203336

Sodium accumulation in the skin is associated with higher density of skin lymphatic vessels in patients with arterial hypertension.

Chachaj A, Stanimirova I, Chabowski M, Gomułkiewicz A, Hodurek P, Glatzel-Plucińska N, Olbromski M, Piotrowska A, Kuzan A, Grzegrzółka J, Ratajczak-Wielgomas K, Nowak A, Szahidewicz-Krupska E, Wiśniewski J, Bromke MA, Podhorska-Okołów M, Gamian A, Janczak D, Dzięgiel P, Szuba A
Advances in medical sciences 2023 Sep;68(2):276-289

A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability.

Li K, Guo J, Ming Y, Chen S, Zhang T, Ma H, Fu X, Wang J, Liu W, Peng Y
Nature communications 2023 Oct 28;14(1):6876

Overexpression of Podoplanin Predicts Poor Prognosis in Patients With Glioma.

He J, Zhang G, Yuan Q, Wang S, Liu Z, Wang M, Cai H, Wan J, Zhao B
Applied immunohistochemistry & molecular morphology : AIMM 2023 May-Jun 01;31(5):295-303

Increased Chymase-Positive Mast Cells in High-Grade Mucoepidermoid Carcinoma of the Parotid Gland.

Nishimura H, Jin D, Kinoshita I, Taniuchi M, Higashino M, Terada T, Takai S, Kawata R
International journal of molecular sciences 2023 May 5;24(9)

A SCID mouse-human lung xenograft model of SARS-CoV-2 infection.

Fu W, Wang W, Yuan L, Lin Y, Huang X, Chen R, Cai M, Liu C, Chen L, Zhou M, Wu K, Zhao H, Pan D, Ma J, Hong J, Zhai B, Zhang Y, Kong Z, Wang Y, Chen Y, Yuan Q, Zhu H, Cheng T, Guan Y, Xia N
Theranostics 2021;11(13):6607-6615

Kaposi's sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene.

Ding Y, Chen W, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Sep;17(9):e1009847

Characterization of kaposiform lymphangiomatosis tissue-derived cells.

Nozawa A, Ozeki M, Yasue S, Endo S, Noguchi K, Kanayama T, Tomita H, Aoki Y, Ohnishi H
Pediatric blood & cancer 2021 Oct;68(10):e29086

Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.

Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Dec;17(12):e1009600

Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.

Nikolić MZ, Caritg O, Jeng Q, Johnson JA, Sun D, Howell KJ, Brady JL, Laresgoiti U, Allen G, Butler R, Zilbauer M, Giangreco A, Rawlins EL
eLife 2017 Jun 30;6

Podoplanin Expression Correlates with Disease Progression in Mycosis Fungoides.

Jankowska-Konsur A, Kobierzycki C, Grzegrzółka J, Piotrowska A, Gomulkiewicz A, Glatzel-Plucinska N, Reich A, Podhorska-Okołów M, Dzięgiel P, Szepietowski JC
Acta dermato-venereologica 2017 Feb 8;97(2):235-241

Altered expression of podoplanin in keratocystic odontogenic tumours following decompression.

Zhang X, Wang J, Ding X, Xing S, Zhang W, Wang L, Wu H, Wang L
Oncology letters 2014 Mar;7(3):627-630

Platelets direct monocyte differentiation into epithelioid-like multinucleated giant foam cells with suppressive capacity upon mycobacterial stimulation.

Feng Y, Dorhoi A, Mollenkopf HJ, Yin H, Dong Z, Mao L, Zhou J, Bi A, Weber S, Maertzdorf J, Chen G, Chen Y, Kaufmann SH
The Journal of infectious diseases 2014 Dec 1;210(11):1700-10

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 11629-1-AP(PDPN,D2-40,M2A antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Podoplanin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Podoplanin. This antibody recognizes human antigen. The Podoplanin antibody has been validated for the following applications: ELISA, IHC analysis.
Appendix: 11629-1-AP.pdf

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