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- References [14]
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- Immunohistochemistry [1]
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- Product number
- 12192-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12192-1-AP, RRID:AB_10344682
- Product name
- Alpha Antichymotrypsin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Antichymotrypsin antibody (Cat. #12192-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic Effects of Noninvasive Electrical Stimulation in Combination Transplantation of Human Adipose-Derived Stem Cells-Derived Dopaminergic Neuron on the Monkey Model of Parkinson's Disease.
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning.
Identification of liver proteins as biomarker for postmortem diagnosis of heat stroke through proteomics.
Maternal exercise prevents metabolic disorders in offspring mice through SERPINA3C.
Proteomic profiling reveals the molecular signatures of chemotherapy-induced human ovarian damage.
PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina3.
SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS.
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD.
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Synaptic proteomics reveal distinct molecular signatures of cognitive change and C9ORF72 repeat expansion in the human ALS cortex.
Serum protein profiling in diffuse large B-cell lymphoma.
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Huang C, Gao S, Zheng X, Song X, Wu J, Liao K, Li J, Lin Y, Li C, Lu Y, Feng J, Wei H, Wang L, Xu H, Wang W, Chen Y, Wu J, Gao J, Song J, Shi C, Zhang J, Yan S
MedComm 2026 Feb;7(2):e70595
MedComm 2026 Feb;7(2):e70595
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning.
Yuan Y, Jiang H, Xue R, Feng XJ, Liu BF, Li L, Peng B, Ren CS, Li SM, Li N, Li M, Wang DB, Zhang XE
Journal of extracellular vesicles 2025 May;14(5):e70078
Journal of extracellular vesicles 2025 May;14(5):e70078
Identification of liver proteins as biomarker for postmortem diagnosis of heat stroke through proteomics.
Pan M, Liu H, Sun T, Ma C, Yang L, Dong H
Scientific reports 2025 May 16;15(1):17075
Scientific reports 2025 May 16;15(1):17075
Maternal exercise prevents metabolic disorders in offspring mice through SERPINA3C.
Li Y, Li RY, Zhu JY, Chen M, Mu WJ, Luo HY, Li S, Yan LJ, Yin MT, Li X, Chen HM, Guo L
Nature metabolism 2025 Feb;7(2):401-420
Nature metabolism 2025 Feb;7(2):401-420
Proteomic profiling reveals the molecular signatures of chemotherapy-induced human ovarian damage.
Grosbois J, Bisteau X, Imbault V, Conrard L, Condorelli M, Findikli N, Lybaert P, Demeestere I
Human reproduction (Oxford, England) 2025 Dec 1;40(12):2395-2408
Human reproduction (Oxford, England) 2025 Dec 1;40(12):2395-2408
PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina3.
Hu L, Liu M, Tang B, Li X, Xu H, Wang H, Wang D, Liu S, Xu C
Cancer gene therapy 2024 Nov;31(11):1696-1707
Cancer gene therapy 2024 Nov;31(11):1696-1707
SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.
Barter MJ, Turner DA, Rice SJ, Hines M, Lin H, Falconer AMD, McDonnell E, Soul J, Arques MDC, Europe-Finner GN, Rowan AD, Young DA, Wilkinson DJ
Matrix biology : journal of the International Society for Matrix Biology 2024 Nov;133:33-42
Matrix biology : journal of the International Society for Matrix Biology 2024 Nov;133:33-42
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS.
Aly A, Laszlo ZI, Rajkumar S, Demir T, Hindley N, Lamont DJ, Lehmann J, Seidel M, Sommer D, Franz-Wachtel M, Barletta F, Heumos S, Czemmel S, Kabashi E, Ludolph A, Boeckers TM, Henstridge CM, Catanese A
Acta neuropathologica 2023 Sep;146(3):451-475
Acta neuropathologica 2023 Sep;146(3):451-475
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Gao S, Chao Y, Li N, Li H, Zhao H, Liu X, Chen W, Dong X
Frontiers in medicine 2022;9:805356
Frontiers in medicine 2022;9:805356
Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD.
Wang D, Chen B, Bai S, Zhao L
Frontiers in immunology 2022;13:967357
Frontiers in immunology 2022;13:967357
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Liu Z, Liu R, Wang R, Dai J, Chen H, Wang J, Li X
Food & function 2022 Oct 3;13(19):9973-9987
Food & function 2022 Oct 3;13(19):9973-9987
Synaptic proteomics reveal distinct molecular signatures of cognitive change and C9ORF72 repeat expansion in the human ALS cortex.
Laszlo ZI, Hindley N, Sanchez Avila A, Kline RA, Eaton SL, Lamont DJ, Smith C, Spires-Jones TL, Wishart TM, Henstridge CM
Acta neuropathologica communications 2022 Oct 29;10(1):156
Acta neuropathologica communications 2022 Oct 29;10(1):156
Serum protein profiling in diffuse large B-cell lymphoma.
Riby J, Mobley J, Zhang J, Bracci PM, Skibola CF
Proteomics. Clinical applications 2016 Nov;10(11):1113-1121
Proteomics. Clinical applications 2016 Nov;10(11):1113-1121
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Jin Y, Wang J, Ye X, Su Y, Yu G, Yang Q, Liu W, Yu W, Cai J, Chen X, Liang Y, Chen Y, Wong BH, Fu X, Sun H
British journal of cancer 2016 Mar 1;114(5):532-44
British journal of cancer 2016 Mar 1;114(5):532-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 12192-1-AP(SERPINA3,AACT antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The alpha 1 Antichymotrypsin / AACT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha 1 Antichymotrypsin / AACT. This antibody recognizes human antigen. The alpha 1 Antichymotrypsin / AACT antibody has been validated for the following applications: ELISA, IHC, WB analysis.
