abx004426

antibody from Abbexa

Targeting: PNP NP, PUNP

Western blot (Recommended by provider)

Antibody Data

Product number

abx004426

Provider

Abbexa

Product name

Purine Nucleoside Phosphorylase (PNP) Antibody

Antibody type

Polyclonal

Description

PNP Antibody is a Rabbit Polyclonal antibody against PNP. This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.