15902-1-AP

antibody from Proteintech Group

Targeting: GSTP1 FAEES3, GST3, GSTP

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

15902-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#15902-1-AP, RRID:AB_2116216

Product name

GSTP1 antibody

Antibody type

Polyclonal

Description

KD/KO validated GSTP1 antibody (Cat. #15902-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

SIRT5-related lysine demalonylation of GSTP1 contributes to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy.

Wei C, Shi M, Dong S, Li Z, Zhao B, Liu D, Li G, Cen J, Yu L, Liang X, Shi L
International journal of biological sciences 2024;20(2):585-605

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N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.

Duan WL, Ma YP, Wang XJ, Ma CS, Han B, Sheng ZM, Dong H, Zhang LY, Li PA, Zhang BG, He MT
European journal of pharmacology 2024 Jun 5;972:176553

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Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studies.

Zhao Y, Yakufu M, Ma C, Wang B, Yang J, Hu J
Molecular medicine reports 2024 Jan;29(1)

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Natural product P57 induces hypothermia through targeting pyridoxal kinase.

Wang R, Xiao L, Pan J, Bao G, Zhu Y, Zhu D, Wang J, Pei C, Ma Q, Fu X, Wang Z, Zhu M, Wang G, Gong L, Tong Q, Jiang M, Hu J, He M, Wang Y, Li T, Liang C, Li W, Xia C, Li Z, Ma DK, Tan M, Liu JY, Jiang W, Luo C, Yu B, Dang Y
Nature communications 2023 Sep 26;14(1):5984

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GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.

Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S
Redox biology 2023 May;61:102635

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Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells.

Nguyen V, Kravitz J, Gao C, Hochman ML, Meng D, Chen D, Wang Y, Jegga AG, Nelson JS, Tan W
bioRxiv : the preprint server for biology 2023 Jul 19;

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RNA-binding protein SPEN controls hepatocyte maturation via regulating Hnf4α expression during liver development.

Zhang J, Yang Z, Yan X, Duan J, Ruan B, Zhang X, Wen T, Zhang P, Liang L, Han H
Biochemical and biophysical research communications 2023 Jan 29;642:128-136

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SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.

Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y
Molecular cell 2023 Dec 7;83(23):4352-4369.e8

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Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells.

Nguyen V, Kravitz J, Gao C, Hochman ML, Meng D, Chen D, Wang Y, Jegga AG, Nelson JS, Tan W
Metabolites 2023 Aug 31;13(9)

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Decreased Klotho Expression Causes Accelerated Decline of Male Fecundity through Oxidative Injury in Murine Testis.

Wang YY, Lin YH, Wu VC, Lin YH, Huang CY, Ku WC, Sun CY
Antioxidants (Basel, Switzerland) 2023 Aug 25;12(9)

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Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.

Zhu H, Yan C, Yao P, Li P, Li Y, Yang H
Free radical biology & medicine 2023 Aug 1;204:54-67

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Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.

Chang T, Lian Z, Ma S, Liang Z, Ma X, Wen X, Wang Y, Liu R
The Prostate 2023 Apr;83(5):470-486

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Comparative Analysis of Proteomic of Curcumin Reversing Multidrug Resistance in HCT-8/VCR Cells.

Li L, Yu L, Cao X, Zhang C, Liu Q, Chen J
Journal of oncology 2022;2022:3605436

---

COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.

Zhang H, Yan T, Zhong A, Guo L, Lu R
Current issues in molecular biology 2022 Sep 1;44(9):3948-3958

---

Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.

Jin C, Min F, Zhong Y, Sun D, Luo R, Liu Q, Peng X
Toxicology letters 2022 Mar 1;356:110-120

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Study of Drug Resistance in Chemotherapy Induced by Extracellular Vesicles on a Microchip.

Fang T, Lu W, Zhang J, Ge K, Chen Z, Wang M, Yao B
Analytical chemistry 2022 Dec 6;94(48):16919-16926

---

TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.

Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC
The Journal of cell biology 2021 Sep 6;220(9)

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Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex.

Liu X, Blazejewski SM, Bennison SA, Toyo-Oka K
Human molecular genetics 2021 Mar 25;30(1):30-45

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In Vitro and in Vivo Efficacy of NBDHEX on Gefitinib-resistant Human Non-small Cell Lung Cancer.

Sha H, Dong S, Yu C, Zou R, Zhu Y, Lu Y, Zhang J, Cao H, Chen D, Wu J, Feng J
Journal of Cancer 2020;11(24):7216-7223

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Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.

Ye L, Chen T, Cao J, Sun L, Li W, Zhang C
International journal of oncology 2020 Nov;57(5):1116-1128

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Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies.

Xu M, Yang Q, Xu L, Rao Z, Cao D, Gao M, Liu S
Particle and fibre toxicology 2019 Nov 27;16(1):46

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Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.

Wang C, Xu W, Zhang Y, Huang D, Huang K
Cell death & disease 2018 Jul 26;9(8):819

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Prognostic significance of GSTP1 in patients with triple negative breast cancer.

Chen G, Zhang H, Sun L, Jiang Y, Xu Z, Gu H, Xu H, Yang J, Wang Y, Xu T, Zhang Y, Liu C
Oncotarget 2017 Sep 15;8(40):68675-68680

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The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.

Zheng ZG, Xu H, Suo SS, Xu XL, Ni MW, Gu LH, Chen W, Wang LY, Zhao Y, Tian B, Hua YJ
Scientific reports 2016 May 19;6:26093

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MicroRNA-133b targets glutathione S-transferase π expression to increase ovarian cancer cell sensitivity to chemotherapy drugs.

Chen S, Jiao JW, Sun KX, Zong ZH, Zhao Y
Drug design, development and therapy 2015;9:5225-35

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Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice.

Conklin DJ, Haberzettl P, Jagatheesan G, Baba S, Merchant ML, Prough RA, Williams JD, Prabhu SD, Bhatnagar A
Toxicology and applied pharmacology 2015 Jun 1;285(2):136-48

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Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM
Age (Dordrecht, Netherlands) 2014;36(4):9687

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Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

Rojanathammanee L, Rakoczy S, Brown-Borg HM
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Oct;69(10):1199-211

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Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.

Shirai M, Arakawa S, Miida H, Matsuyama T, Kinoshita J, Makino T, Kai K, Teranishi M
Journal of toxicologic pathology 2013 Jun;26(2):175-86

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Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice.

Yu H, Wark L, Ji H, Willard L, Jaing Y, Han J, He H, Ortiz E, Zhang Y, Medeiros DM, Lin D
Molecular nutrition & food research 2013 Jul;57(7):1158-69

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Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer's disease.

Chang SH, Jung IS, Han GY, Kim NH, Kim HJ, Kim CW
Biochemical and biophysical research communications 2013 Jan 11;430(2):670-5

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Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells.

Song J, Zhao M, Liu X, Zhu Y, Hu X, Chen F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Aug;58:306-10

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Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight.

Cologna SM, Jiang XS, Backlund PS, Cluzeau CV, Dail MK, Yanjanin NM, Siebel S, Toth CL, Jun HS, Wassif CA, Yergey AL, Porter FD
PloS one 2012;7(10):e47845

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Jurkat cells were subjected to SDS PAGE followed by western blot with 15902-1-AP(GSTP1 antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells using 15902-1-AP( GSTP1 Antibody) at dilution of 1:50 and N/A

Sample type

cell line

Immunoprecipitation

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

IP Result of anti-GSTP1 (IP:15902-1-AP, 3ug; Detection:15902-1-AP 1:800) with mouse brain tissue lysate 4000ug.

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human skin using 15902-1-AP(GSTP1 antibody) at dilution of 1:100 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human skin using 15902-1-AP(GSTP1 antibody) at dilution of 1:100 (under 40x lens)

Sample type

tissue

Flow cytometry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The GSTP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GSTP1. This antibody recognizes human,mouse,rat antigen. The GSTP1 antibody has been validated for the following applications: ELISA, WB, IHC, IF, IP, FC analysis.

Appendix

15902-1-AP.pdf

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