Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 20967-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- CRHR1 antibody
- Antibody type
- Polyclonal
- Description
- CRHR1 antibody (Cat. #20967-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Corticotropin-releasing hormone signaling from piriform cortex to amygdala mediates social homophily in opioid addiction.
Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells.
Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice.
Tea-derived exosome-like nanoparticles prevent irritable bowel syndrome induced by water avoidance stress in rat model.
Lactobacillus reuteri or Lactobacillus rhamnosus GG intervention facilitates gut barrier function, decreases corticosterone and ameliorates social behavior in LPS-exposed offspring.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Antidepressant effect of 4-Butyl-alpha-agarofuran via HPA axis and serotonin system.
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Dynamic expression of corticotropin-releasing hormone and urocortin in estrogen induced-cholestasis pregnant rat.
Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema.
Huo Y, Wang X, Lin X, Yu J, Li B, Liu Z, Guo S, Wang Y, Tang R, Li B, Zhang S, Zhang Y, Jiang Z, Fan X, Ye X, Li Y, Zhang X, Yao Y, Song S, Xu M, Jiang H, Xing G, Wan Y, Cui C, Li Y, Sun L
Neuron 2025 Nov 5;113(21):3632-3646.e7
Neuron 2025 Nov 5;113(21):3632-3646.e7
Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells.
Tao Y, Li X, Dong Q, Kong L, Petersen AJ, Yan Y, Xu K, Zima S, Li Y, Schmidt DK, Ayala M, Mathivanan S, Sousa AMM, Chang Q, Zhang SC
Nature biotechnology 2024 Sep;42(9):1404-1416
Nature biotechnology 2024 Sep;42(9):1404-1416
Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice.
Ding SM, Shi LG, Xing F, Cui SS, Cheng HR, Liu Y, Ji DM, Liang D, Cao YX, Liu YJ
Reproductive sciences (Thousand Oaks, Calif.) 2024 Oct;31(10):3191-3201
Reproductive sciences (Thousand Oaks, Calif.) 2024 Oct;31(10):3191-3201
Tea-derived exosome-like nanoparticles prevent irritable bowel syndrome induced by water avoidance stress in rat model.
Gong Q, Xiong F, Zheng Y, Guo Y
Journal of gastroenterology and hepatology 2024 Dec;39(12):2690-2699
Journal of gastroenterology and hepatology 2024 Dec;39(12):2690-2699
Lactobacillus reuteri or Lactobacillus rhamnosus GG intervention facilitates gut barrier function, decreases corticosterone and ameliorates social behavior in LPS-exposed offspring.
Wang X, Hu R, Lin F, Yang T, Lu Y, Sun Z, Li T, Chen J
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115212
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115212
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Antidepressant effect of 4-Butyl-alpha-agarofuran via HPA axis and serotonin system.
Wang H, Hu J, Hu J, Chen Q, Shang N, Liu M, Li X, Xiang L, Yin D, Lan J, Xiao Q, Peng Y
Brain research bulletin 2023 Jun 15;198:3-14
Brain research bulletin 2023 Jun 15;198:3-14
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sun Y, Li H, Liu L, Bai X, Wu L, Shan J, Sun X, Wang Q, Guo Y
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, Li S, Wu R, Yang H, Lian S
Brain research 2019 Nov 1;1722:146354
Brain research 2019 Nov 1;1722:146354
Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats.
Lian S, Xu B, Wang D, Wang L, Li W, Yao R, Ji H, Wang J, Guo J, Li S, Yang H
Behavioural brain research 2019 Feb 1;359:304-311
Behavioural brain research 2019 Feb 1;359:304-311
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Dynamic expression of corticotropin-releasing hormone and urocortin in estrogen induced-cholestasis pregnant rat.
Zhou F, Gao B, Deng C, Huang G, Xu T, Wang X
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:179-186
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:179-186
Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema.
Chen SJ, Yang JF, Kong FP, Ren JL, Hao K, Li M, Yuan Y, Chen XC, Yu RS, Li JF, Leng G, Chen XQ, Du JZ
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 9;111(36):13199-204
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 9;111(36):13199-204
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The CRHR1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CRHR1. This antibody recognizes human antigen. The CRHR1 antibody has been validated for the following applications: ELISA, WB analysis.