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- References [1129]
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- Product number
- 10373-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10373-2-AP, RRID:AB_2250823
- Product name
- MMP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MMP2 antibody (Cat. #10373-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lymph Node Metastasis-Associated Spatiotemporal Mapping of the TFF3-Linked Niche in Breast Cancer: Integrating Radiogenomic Signatures with Immune-Ecosystem Remodeling.
Identification of Inhibitors for eIF5A2-Dependent Translation Elongation by Monitoring the Translational Efficiency of Polyproline Motif in Mitochondrial Fission Regulator 1.
Versatile Nanotherapeutics for Enhancing Sonodynamic Therapy/Chemotherapy of Thyroid Cancer through Remodeling Tumor Microenvironment and Synergistic Reactive Oxygen Species Augment.
An Injectable Photothermal Responsive Liposome Hydrogel Co-Loaded with Bufalin, Apatinib, and IR820 for Inhibiting Postoperative Recurrence of Colon Cancer.
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Targeting the LINC01515/miR-325-3p/ERBB4 axis suppresses gastric cancer progression.
Injectable Cu(2+) loaded rhein hydrogel for cross-amplifying osteosarcoma apoptosis and cuproptosis epitranscriptomically.
Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation.
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression.
TSG101 Promotes SIAH1 Auto-Ubiquitination to Drive Migration and Invasion in Hepatocellular Carcinoma Cells.
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Inhibition of CDC20 suppresses the development and progression of mantle cell lymphoma through PI3K/AKT pathway.
Cellular Effects and Regulated Protein Expression of MCF-7 Breast Cancer Cells Following Exposure to PAH Derivative 3-Hydroxybenz[a]anthracene.
Polystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism.
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
Hedyotis diffusa and Scutellaria barbata enhance the anti-ovarian cancer effect of cisplatin through network pharmacology analysis and molecular docking technology.
Nicotine Activates PI3K/AKT Pathway to Induce Cellular Proliferation, Invasion, and Migration in HPV-16 Positive Cervical Cancer SiHa Cells.
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Paeoniflorin suppresses the phenotypic transformation of vascular smooth muscle cells during atherosclerosis by regulating the MAPK/NF-κB pathways and ABCA1 expression.
The microbial metabolite isovaleric acid aggravates gelatinase-mediated periodontal tissue destruction via the NF-κB signaling pathway.
piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization.
Enhanced anti-tumor efficacy of prNK-lysin delivered by injectable pH-responsive hydrogel in the treatment of orthotopic breast cancer.
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
IL-36 participated in airway remodeling in chronic asthma model by inducing epithelial-mesenchymal transition process.
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
Buspirone hydrochloride: a potential regulator of PD-L1 for enhanced antitumor activity in melanoma-bearing mice.
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
SERPINA4 facilitates colorectal cancer progression through m⁶A-dependent stabilization.
Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8.
Discovery of Novel Snail Inhibitors Derived from Omeprazole for Antiatherosclerotic Therapy: A Structure-Based Approach.
DNMT3b promotes proliferation and invasion by mediating HOPX DNA methylation in lung cancer.
Fluoxetine suppresses triple-negative breast cancer progression by inducing apoptosis, inhibiting Src-mediated invasiveness, and enhancing anti-tumor immunity.
S100A10 promotes glycolysis and malignant progression of CCA by activating the HK2/ERK signaling pathway.
LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism.
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Rabdosin B suppresses proliferation of nonsmall cell lung cancer by regulating the SRC/PI3K/AKT signaling pathway.
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
Hyodeoxycholic acid relieves neuropathic pain by activating farnesoid X receptor signaling.
TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.
AKAP2 is required for assembly of cytoskeletal signaling complexes that promote growth and metastasis of triple-negative breast cancer.
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis.
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Structure-based discovery of a novel allosteric activator of ATG4B for the treatment of triple-negative breast cancer.
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation.
Sono-Gas-Mediated Precise Stiffness Remodeling for Triple-Negative Breast Cancer Mechanical Immunotherapy.
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression.
Lathyrol affects the expression of AR and PSA and inhibits the malignant behavior of RCC cells.
Association between TGF-β1 and β-catenin expression in the vaginal wall of patients with pelvic organ prolapse.
Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor.
Catalpol Alleviates HFpEF via Inhibition of the S100A8-RAGE-NOX4 Inflammatory Axis in Murine Hearts.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
Longikaurin A, a natural ent-kaurane, suppresses proliferation, invasion and tumorigenicity in oral squamous cell carcinoma cell by via inhibiting PI3K/Akt pathway in vitro and in vivo.
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
HMGA2 interacts with KAT6A to regulate MMPs chromatin architecture and promote triple-negative breast cancer metastasis.
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts.
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
LncRNA BANCR/miR-15a/MAPK1 Induces Apoptosis and Increases Proliferation of Vascular Smooth Muscle Cells in Aortic Dissection by Enhancing MMP2 Expression.
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Ubiquitin-specific protease 7-mediated stabilization of discoidin domain receptor 1 drives progression of TP53-Mutant cancers.
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion.
Microenvironment-driven transformable self-assembly nanoplatform enables spatiotemporal remodeling for rheumatoid arthritis therapy.
NGAL knockdown alleviated CSE-induced cellular senescence and reduced MMP2 and MMP9 expression in alveolar macrophages through the PI3K/Akt pathway.
KLF9 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Regulating Ceramide Synthase 1 Synthesis.
JunB orchestrates macrophage-fibroblast crosstalk in silica nanoparticle-induced pulmonary fibrosis.
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Bushen Jiangu decoction alleviates osteoporosis by inhibiting MMP2 expression and activation of the MAPK pathway in vitro.
Cationic microbubble loading hSIRT3 and hTIMP3 optimize cardiac-targeted delivery and myocardial protection in the porcine MI/R model.
A dual-functional mitochondrial probe for melanoma visualization and PI3K/AKT/mTOR-EMT signaling axis-mediated antitumor therapy.
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
Selection and identification of a novel DNA aptamer for recognizing colorectal cancer stem cells.
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
Salvigenin inhibits gastric cancer progression by suppressing the EGFR/PI3K/AKT pathway.
An integrative bioinformatics approach unveils fibrosis-driven prognostic signature and immunotherapeutic potential in kidney renal clear cell carcinoma.
Selection and characterization of novel DNA aptamers targeting colorectal cancer cells with malignant potential.
Bone morphogenetic protein 1 as a macromolecular pan-cancer biomarker modulating the immune microenvironment and malignant phenotypes in glioblastoma.
LncRNA LINC01605 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection Through Regulating SGK1.
GCN2 promotes fatty acid metabolism through the activation of PI3K/AKT signaling in gastric cancer.
KLK1 as an Epithelial-Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R-Mediated Fibroblast Phenotypic Transition.
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
BRG1 Ablation in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm: Mechanism and Translational Potential.
Sorting nexin 9 expression and prognostic implications in lung adenocarcinoma: integrative bioinformatic and in vitro validation.
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
Targeting the p38/MAPK pathway to induce apoptosis: a multidimensional mechanistic exploration of Mentha and its active compound diosmetin against liver cancer.
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Precision hyperthermia-induced HSP20 inhibits gastric cancer cell invasion, migration, and proliferation.
Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD.
Methylparaben and propylparaben promote bladder cancer invasion via MMP2 and PPARG modulation.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
METTL1 Enhances RRP9 mRNA Stability Through m7G Modification to Drive Colorectal Tumorigenesis.
Cohesin Complex Interacting with Promoters of MMP Genes for in Pterygium Occurrence.
RBM15-mediated the m6A modification of MAT2A promotes osteosarcoma cell proliferation, metastasis and suppresses ferroptosis.
RTA activates the activity of the miR-155 promoter region and promotes the growth and invasion of endothelial cells through the regulatory network of miR-155/GATA3/STAT3.
lncRNA ZNF667‑AS1 inhibits ovarian cancer progression by interacting with the TNF signaling pathway.
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway.
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
CKIP-1 inhibits M2 macrophage polarization to suppress the progression of gastric cancer by inactivating JAK/STAT3 signaling.
Kidney Gastrin/CCKBR Attenuates Type 2 Diabetes Mellitus by Inhibiting SGLT2-Mediated Glucose Reabsorption through Erk/NF-κB Signaling Pathway.
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer.
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Unmodified RNA sequences form unusual stable G-quadruplexes with potential anti-RSV and anti-angiogenesis applications.
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
TSPAN31 Activates Fatty Acid Metabolism and PI3K/AKT Pathway to Promote Tumor Progression in Breast Cancer.
Enhancing the antioxidant capacity of Fe single-atom nanozymes through local coordination manipulation for psoriasis treatment.
DEP domain‑containing 1 is a prognostic biomarker associated with the cell cycle in gliomas.
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
Network pharmacology and experimental validation reveals the potential therapeutic effects of Polygonum cuspidatum against odontogenic keratocyst.
Aerobic Exercise Upregulates Renal-Derived ELABELA to Improve Myocardial Fibrosis by Activating APJ-AMPK-Sirt1 and Inhibiting TGFβ1-Smad2/3 Signaling Pathways in Myocardial Infarction Mice.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Sinomenine Ameliorates Liver Fibrosis by Blocking TGF-β/SMAD and c-JUN Signaling.
Ethanolic Extract of Atractylodis Rhizoma Ameliorates DSS-Induced Ulcerative Colitis via Improving Intestinal Barrier Function Through the Rho-Associated Kinase/Myosin Light Chain Pathway.
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
Matrix metalloproteinase-2 as a novel regulator of glucose utilization by adipocytes.
Ursodeoxycholic acid alleviates aortic aneurysm and dissection through the intestinal farnesoid X receptor/ceramide synthase 2 axis.
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Lingguizhugan decoction inhibit pulmonary hypertension by regulating macrophage IL-6 secretion via IL-33/ST2 pathway.
Growth Hormone Signaling in Bladder Cancer: Transcriptomic Profiling of Patient Samples and In Vitro Evidence of Therapy Resistance via ABC Transporters and EMT Activation.
Targeting LINC02320 prevents colorectal cancer growth via GRB7-dependent inhibition of MAPK signaling pathway.
Qingrehuoxue formula enhances anti-PD-1 immunotherapy in NSCLC by remodeling the tumor immune microenvironment via TREM2 signaling.
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
Enhancing the therapeutic efficacy of gemcitabine in bladder cancer through TGF-β1 inhibition and pluronic F-127-based microsphere delivery.
Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction.
THBS4 downregulation alters trophoblast function in preeclampsia via the TGF-β1/Smad signaling cascade.
Tea polyphenols nanoparticles integrated with microneedles multifunctionally boost 5-aminolevulinic acid photodynamic therapy for skin cancer.
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
N6-methyladenosine modification of SPOP relieves ferroptosis and diabetic cardiomyopathy by enhancing ubiquitination of VDAC3.
FSTL1 protects against acute aortic dissection by suppressing vascular smooth muscle cell phenotypic switching and degradation of the extracellular matrix.
The double face of licorice-kansui herb pair: Cure or curse, depending on the combining ratio and mediated by hydrogen sulfide.
Novel applications of metformin in the treatment of septic myocardial injury based on metabolomics and network pharmacology.
Lactamase β reprograms lipid metabolism to inhibit the progression of endometrial cancer through attenuating MDM2-mediated p53 ubiquitination and degradation.
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
GPX3 Overexpression Ameliorates Cardiac Injury Post Myocardial Infarction Through Activating LSD1/Hif1α Axis.
Effect of the IL-6 trans-signaling pathway in the absence or presence of TGF-β2 on Schlemm's canal endothelial cells.
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Exosomal miRNA reprogramming in pyroptotic macrophage drives silica-induced fibroblast-to-myofibroblast transition and pulmonary fibrosis.
Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection.
RPL22L1 fosters malignant features of cervical cancer via the modulation of DUSP6-ERK axis.
Decoding the heterogeneous subpopulations of glioblastoma for prognostic stratification and uncovering the promalignant role of PSMC2.
Dihydroartemisinin inhibits EphA2/PI3K/Akt pathway-mediated malignant behaviors and vasculogenic mimicry in glioma stem cells.
Inhibition Effects and Mechanism Study of rAj-HRP30, a Recombinant Histidine-Rich Peptide from Apostichopus japonicus, on the Viability of Pancreatic Ductal Adenocarcinoma Cells Panc01 and Panc02.
Bruton tyrosine kinase promotes wound healing after myocardial infarction by inhibiting the transcription of u-PA.
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Isobutyric Acid Regulates Gelatinase Secretion by Human Periodontal Ligament Stem Cells Via NF-κB Signalling.
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Bioactive recombinant human elastin gel for reconstructing elastic fibers and rejuvenating endogenously aged skin.
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
Different Intensities of Exercise Affect the Prognosis of Ventricular Aneurysm in Mice by Regulating the Progression of Cardiac Fibrosis.
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
Metabolic signatures for gastric cancer diagnosis and mechanistic insights: a multicenter study.
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
Identification and functional characterization of genes associated with lipopolysaccharide in lung adenocarcinoma.
Alkaloids isolated from Scutellaria Barbata D. Don trigger apoptosis and inhibit migration by modulating the p38-p53 pathway in ovarian cancer.
Decreased scleral Wnt5a(hi) fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.
Impaired decidualization and angiogenesis in eutopic endometrium of endometriosis: insights from in vitro models†.
Resveratrol Derivatives with a Urea Backbone Exert Anticancer Effects against Liver Cancer via Apoptosis Induction and Metastasis Inhibition.
Genetic and pharmacological targeting of Snail inhibits atherosclerosis by relieving intraplaque endothelium dysfunction and associated inflammation.
Inhibition of VSMC Ferroptosis Mitigates Pathological Vascular Remodeling: A Novel Therapeutic Strategy for Abdominal Aortic Aneurysm.
Branched-chain amino acids promote gelatinase secretion from human periodontal ligament stem cells through nuclear factor kappa-B signaling.
SOX15 Transcriptionally Decreases the Level of MMP2 and Inhibits Vasculogenic Mimicry to Slow Down the Progression of Ovarian Cancer.
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
FTO-mediated the destabilization of RASGRF1 mRNA impedes thyroid cancer progression and suppresses macrophage M2 polarization.
WTAP Dysregulation Mediates HLF-m6A Modification to Inhibit Trophoblast Ferroptosis in Preeclampsia.
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Oroxin A suppresses colorectal tumor growth by regulating the TRIM24-mediated ferroptosis and TSPO pathway.
Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer.
Spatial transcriptomics and single-cell RNA-sequencing revealed dendritic cell-mediated inflammation in keratoconus.
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
LC-MS/MS assay to confirm that the endogenous metabolite L-Arginine promotes trophoblast invasion in the placenta accreta spectrum through upregulation of the GPRC6A/PI3K/AKT pathway.
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Impact of Escherichia coli and Lipopolysaccharide on the MAPK Signaling Pathway, MMPs, TIMPs, and the uPA System in Bovine Mammary Epithelial Cells.
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Dihydroartemisinin Regulated the MMP-Mediated Cellular Microenvironment to Alleviate Rheumatoid Arthritis.
USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model.
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Huangqi-Danshen Decoction Against Renal Fibrosis in UUO Mice via TGF-β1 Induced Downstream Signaling Pathway.
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Epigenetic silencing of KCTD8 promotes hepatocellular carcinoma growth by activating PI3K/AKT signaling.
MiR-760 exerts a critical regulatory role in glioma proliferation, migration, and invasion by modulating MMP2 expression.
The cancer-associated fibroblasts interact with malignant T cells in mycosis fungoides and promote the disease progression.
O304 alleviates abdominal aortic aneurysm formation via AMPK/mTOR/MMP pathway activation.
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
The potential of brimonidine for myopia treatment: Targeting MMP-2 to regulate choroidal thickness and control eye growth.
CCDC113 promotes colorectal cancer tumorigenesis and metastasis via TGF-β signaling pathway.
Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia.
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation.
Quercetin promotes the proliferation, migration, and invasion of trophoblast cells by regulating the miR-149-3p/AKT1 axis.
Biomimetic nanocomplex based corneal neovascularization theranostics.
Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration.
BRAF V600E mutation mediates invasive and growth features in ameloblastoma.
Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives.
Transcription factor ETS1‑mediated ECT2 expression promotes the malignant behavior of prostate cancer cells.
The lncRNA TPTEP1 suppresses PI3K/AKT signalling and inhibits ovarian cancer progression by interacting with PTBP1.
CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation.
Targeted Delivery of Celastrol by GA-Modified Liposomal Calcium Carbonate Nanoparticles to Enhance Antitumor Efficacy Against Breast Cancer.
Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics.
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation.
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
IL-32 regulates trophoblast invasion through miR-205-NFκB-MMP2/9 axis contributing to the pregnancy-induced hypertension†.
The role of ALDH1A1 in glioblastoma proliferation and invasion.
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Fat Mass and Obesity-Associated Protein Regulates Granulosa Cell Aging by Targeting Matrix Metalloproteinase-2 Gene Via an N6-Methyladenosine-YT521-B Homology Domain Family Member 2-Dependent Pathway in Aged Mice.
MiR-424-5p Inhibits Proliferation, Migration, Invasion and Angiogenesis of the HTR-8/SVneo Cells Through Targeting LRP6 Mediated β-catenin.
ZnO nanoparticles induce melanoma-like lesions via recruiting dermal dendritic cells in barrier-damaged skin in mice.
Sterile Alpha Motif Domain-Containing 5 Suppresses Malignant Phenotypes and Tumor Growth in Breast Cancer: Regulation of Polo-Like Kinase 1 and c-Myc Signaling in a Xenograft Model.
POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer.
Quercetin Alleviates Scleral Remodeling Through Inhibiting the PERK-EIF2α Axis in Experiment Myopia.
The Inhibitory Effect and Mechanism of the Histidine-Rich Peptide rAj-HRP from Apostichopus japonicus on Human Colon Cancer HCT116 Cells.
Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking.
Restoration of ARA metabolic disorders in vascular smooth muscle cells alleviates intimal hyperplasia.
Circular RNA LDLRAD3 promotes gastric cancer progression by upregulating COL4A5 through sponging miR-h37.
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1.
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma.
Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway.
NSUN2 affects diabetic retinopathy progression by regulating MUC1 expression through RNA m(5)C methylation.
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3'UTR to decrease the expression of CD82.
Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Comparative peptidomics analysis of preeclamptic placenta and the identification of a novel bioactive SERPINA1 C-terminal peptide.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non-small cell lung cancer.
Silica-induced macrophage pyroptosis propels pulmonary fibrosis through coordinated activation of relaxin and osteoclast differentiation signaling to reprogram fibroblasts.
Fibulin 1, targeted by microRNA-24-3p, promotes cell proliferation and migration in vascular smooth muscle cells, contributing to the development of atherosclerosis in APOE(-/-) mice.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis.
Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs.
Cyclin L1 participates in Adriamycin resistance and progression of osteosarcoma via PI3K/AKT-mTOR pathway.
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.
Songorine ameliorates LPS-induced sepsis cardiomyopathy by Wnt/β-catenin signaling pathway-mediated mitochondrial biosynthesis.
Overexpressed FKBP5 mediates colorectal cancer progression and sensitivity to FK506 treatment via the NF-κB signaling pathway.
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
CCZ1 Accelerates the Progression of Cervical Squamous Cell Carcinoma by Promoting MMP2/MMP17 Expression.
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Loss of monopolar spindle-binding protein 3B expression promotes colorectal cancer invasiveness by activation of target of rapamycin kinase/autophagy signaling.
P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma.
Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis.
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner.
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
A drug-free cardiovascular stent functionalized with tailored collagen supports in-situ healing of vascular tissues.
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
miR-146a regulates emphysema formation and abnormal inflammation in the lungs of two mouse models.
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
RETRACTED ARTICLE: MiR-28-5p Promotes Osteosarcoma Development by Suppressing URGCP Expression.
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Glucagon Enhances Chemotherapy Efficacy By Inhibition of Tumor Vessels in Colorectal Cancer.
Ginseng-Sanqi-Chuanxiong (GSC) extracts attenuate d-galactose-induced vascular aging in mice via inhibition of endothelial progenitor cells senescence.
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
Shenlian extract improves atherosclerosis by relieving adventitial inflammation.
Fluvastatin prevents lung metastasis in triple-negative breast cancer by triggering autophagy via the RhoB/PI3K/mTOR pathway.
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation.
Biogenesis of circRBM33 mediated by N6-methyladenosine and its function in abdominal aortic aneurysm.
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Activated PRDM1-CREBBP contributes to preeclampsia by regulating apoptosis and invasion of the human trophoblast cells.
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
FUT3 promotes gastric cancer cell migration by synthesizing Lea on ITGA6 and GLG1, affecting adhesion and vesicle distribution.
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Development and Comparative Study of a Mouse Model of Airway Inflammation and Remodeling Induced by Exosomes Derived from Bone Marrow Mesenchymal Stem Cells.
Melatonin enhances the efficacy of anti-PD-L1 by improving hypoxia in residual tumors after insufficient radiofrequency ablation.
Fc receptor-like A promotes malignant behavior in renal cell carcinoma and correlates with tumor immune infiltration.
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
Activation of P2X7 Receptor Mediates the Abnormal Ovulation Induced by Chronic Restraint Stress and Chronic Cold Stress.
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection.
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Histone deacetylase 9-mediated phenotypic transformation of vascular smooth muscle cells is a potential target for treating aortic aneurysm/dissection.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling.
Establishment of a novel microfluidic co-culture system for simultaneous analysis of multiple indicators of gefitinib sensitivity in colorectal cancer cells.
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells.
Integrating bulk and single-cell sequencing data to construct a Scissor(+) dendritic cells prognostic model for predicting prognosis and immune responses in ESCC.
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
HMGB1 released from dead tumor cells after insufficient radiofrequency ablation promotes progression of HCC residual tumor via ERK1/2 pathway.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Inhibition of Non-small Cell Lung Cancer by Ferroptosis and Apoptosis Induction through P53 and GSK-3β/Nrf2 Signal Pathways using Qingrehuoxue Formula.
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
Pan-cancer analysis shows that IBSP is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including osteosarcoma.
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
The Role of miR-1183: A Potential Suppressor in Hepatocellular Carcinoma via Regulating Splicing Factor SRSF1.
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathway.
Gut Microbiota Metabolite 3-Indolepropionic Acid Directly Activates Hepatic Stellate Cells by ROS/JNK/p38 Signaling Pathways.
Bisphenol P and bisphenol M promote triple-negative breast cancer metastasis through activation of AKT pathways.
[Aumolertinib inhibits proliferation, invasion and migration and promotes apoptosis of neuroblastoma cells by downregulating MMP2 and MMP9 expression].
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Formin-related protein 1 facilitates proliferation and aggressive phenotype of clear cell renal cell carcinoma through MAPK/MMP2 pathway.
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Single-cell RNA sequencing of retina revealed novel transcriptional landscape in high myopia and underlying cell-type-specific mechanisms.
HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Colchicine protects against the development of experimental abdominal aortic aneurysm.
CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia‑induced invasion and therapeutic resistance.
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Hydrogen sulfide inhibits the rupture of fetal membranes throngh anti-aging pathways.
Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
NONHSAG028908.3 sponges miR‑34a‑5p to promote growth of colorectal cancer via targeting ALDOA.
Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma.
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Chrysin protects against cerebral ischemia-reperfusion injury in hippocampus via restraining oxidative stress and transition elements.
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
Accessing Apoptosis Induction and Metastasis Inhibition Effect of Magnolol on Triple Negative Breast Cancer In Vitro.
RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer.
Peptidase Inhibitor 16 Attenuates Left Ventricular Injury and Remodeling After Myocardial Infarction by Inhibiting the HDAC1-Wnt3a-β-Catenin Signaling Axis.
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation.
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx.
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
[DTX2 overexpression promotes migration and invasion of colorectal cancer cells through the Notch2/Akt axis].
Rab32 promotes glioblastoma migration and invasion via regulation of ERK/Drp1-mediated mitochondrial fission.
Integrated miRNA and mRNA omics reveal dioscin suppresses migration and invasion via MEK/ERK and JNK signaling pathways in human endometrial carcinoma in vivo and in vitro.
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
m(6)A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma.
Morusin shows potent antitumor activity for melanoma through apoptosis induction and proliferation inhibition.
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
TEAD4 predicts poor prognosis and transcriptionally targets PLAGL2 in serous ovarian cancer.
EIF4A3-Induced Upregulation of hsa_circ_0040039 is a Biomarker and Aggravates IL-1β-Stimulated Intervertebral Disc Degeneration.
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway.
Aiphanol, a multi-targeting stilbenolignan, potently suppresses mouse lymphangiogenesis and lymphatic metastasis.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Small GTP-binding protein Rap1 mediates EGF and HB-EGF signaling and modulates EGF receptor expression in HTR-8/SVneo extravillous trophoblast cells.
B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
METTL3 and METTL14-mediated N(6)-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
Nanomechanical-based classification of prostate tumor using atomic force microscopy.
SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection.
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34.
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.
Anthraquinone metabolites isolated from the rhizosphere soil Streptomyces of Panax notoginseng (Burk.) F. H. Chen target MMP2 to inhibit cancer cell migration.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis.
Knockdown of Krüppel-Like Factor 9 Inhibits Aberrant Retinal Angiogenesis and Mitigates Proliferative Diabetic Retinopathy.
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell.
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.
Preclinical Evidence of Progesterone as a New Pharmacological Strategy in Human Adrenocortical Carcinoma Cell Lines.
Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation.
Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone.
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway.
Orientin inhibits the progression of fibroblast-like synovial cells in rheumatoid arthritis by regulating MAPK-signaling pathway.
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R(-)/(-)) Mice.
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression.
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells.
ABCA12 Promotes Proliferation and Migration and Inhibits Apoptosis of Pancreatic Cancer Cells Through the AKT Signaling Pathway.
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Kangfuxiaoyanshuan alleviates uterine inflammation and adhesion via inhibiting NF-κB p65 and TGF-β/MMP-2 signaling pathway in pelvic inflammatory disease rats.
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Halofuginone inhibits tumor migration and invasion by affecting cancer-associated fibroblasts in oral squamous cell carcinoma.
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair.
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.
HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα.
Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
A Carabrane-Type Sesquiterpenolide Carabrone from Carpesium cernuum Inhibits SW1990 Pancreatic Cancer Cells by Inducing Ferroptosis.
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
LncRNA n339260 functions in hepatocellular carcinoma progression via regulation of miRNA30e-5p/TP53INP1 expression.
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
MiR-582 Down-Regulates Lissencephaly-1 (LIS1) via P-Akt and MMP-2 to Inhibit Cholangiocarcinoma Cell Proliferation and Invasion.
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
Scinderin Is a Novel Oncogene for Its Correlates with Poor Prognosis, Immune Infiltrates and Matrix Metalloproteinase-2/9 (MMP2/9) in Glioma.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer.
Taraxasterol inhibits inflammation in osteoarthritis rat model by regulating miRNAs and NF-κB signaling pathway.
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m(7)G-modified miR-760-dependent manner.
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation.
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
The programmed site-specific delivery of LY3200882 and PD-L1 siRNA boosts immunotherapy for triple-negative breast cancer by remodeling tumor microenvironment.
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification.
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu).
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Early mobilization in spinal cord injury promotes changes in microglial dynamics and recovery of motor function.
Dexamethasone attenuated thoracic aortic aneurysm and dissection in vascular smooth muscle cell Tgfbr2-disrupted mice with CCL8 suppression.
The molecular mechanism of baicalein repressing progression of gastric cancer mediating miR-7/FAK/AKT signaling pathway.
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Circ_0076305 facilitates prostate cancer development via sponging miR-411-5p and regulating PGK1.
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway.
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Identifying the anti-metastasis effect of Anhydroicaritin on breast cancer: Coupling network pharmacology with experimental validation.
Combination of mitochondria impairment and inflammation blockade to combat metastasis.
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
MiR-665 suppresses the progression of diffuse large B cell lymphoma (DLBCL) through targeting LIM and SH3 protein 1 (LASP1).
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Salidroside Promotes Sensitization to Doxorubicin in Human Cancer Cells by Affecting the PI3K/Akt/HIF Signal Pathway and Inhibiting the Expression of Tumor-Resistance-Related Proteins.
TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer.
Role of Periostin Expression in Non-Small Cell Lung Cancer: Periostin Silencing Inhibits the Migration and Invasion of Lung Cancer Cells via Regulation of MMP-2 Expression.
Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension.
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Lectin-type oxidized LDL receptor 1 modulates matrix metalloproteinase 2 production in peri-implantitis.
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer.
Treatment of malignant pleural effusion in non-small cell lung cancer with VEGF-directed therapy.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Effect of hydroxychloroquine on antiphospholipid antibodies-inhibited endometrial angiogenesis.
Exosomal microRNA-133b-3p from bone marrow mesenchymal stem cells inhibits angiogenesis and oxidative stress via FBN1 repression in diabetic retinopathy.
miR-4443/MMP2 suppresses the migration and invasion of trophoblasts through the HB-EGF/EGFR pathway in preeclampsia.
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Krüppel-like Factor 6 Suppresses the Progression of Pancreatic Cancer by Upregulating Activating Transcription Factor 3.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Chewing Behavior Attenuates Lung-Metastasis-Promoting Effects of Chronic Stress in Breast-Cancer Lung-Metastasis Model Mice.
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
The miR-410-5p /ITGA6 axis participates in the pathogenesis of recurrent abortion by regulating the biological function of trophoblast.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Sparstolonin B inhibits pancreatic adenocarcinoma through the NF-κB signaling pathway.
SEZ6L2, regulated by USF1, accelerates the growth and metastasis of breast cancer.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
LINC00982 Inhibits the Proliferation, Migration, and Invasion of Breast Cancer Cells Through the miR-765/DPF3 Axis.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
miR-340-5p affects oral squamous cell carcinoma (OSCC) cells proliferation and invasion by targeting endoplasmic reticulum stress proteins.
Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway.
LINC00022 acts as an oncogene in colorectal cancer progression via sponging miR-375-3p to regulate FOXF1 expression.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
Circular RNA CircPPP1CB Suppresses Tumorigenesis by Interacting With the MiR-1307-3p/SMG1 Axis in Human Bladder Cancer.
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Cancer-Associated Fibroblasts Promote Vascular Invasion of Hepatocellular Carcinoma via Downregulating Decorin-integrin β1 Signaling.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
The Mechanism of miR-141 Regulating the Proliferation and Metastasis of Liver Cancer Cells by Targeting STAT4.
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells.
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke.
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Induction of Apoptosis and Inhibition of EGFR/NF-κB Signaling Are Associated With Regorafenib-sensitized Non-small Cell Lung Cancer to Cisplatin.
Integrative analysis of genome-wide DNA methylation and single-nucleotide polymorphism identified ACSM5 as a suppressor of lumbar ligamentum flavum hypertrophy.
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness.
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
An inducible rodent glaucoma model that exhibits gradual sustained increase in intraocular pressure with distinct inner retina and optic nerve inflammation.
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
A reproducible swine model of a surgically created saccular thoracic aortic aneurysm.
L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Amentoflavone Induces Cell-cycle Arrest, Apoptosis, and Invasion Inhibition in Non-small Cell Lung Cancer Cells.
Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4.
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Bone marrow stem cells secretome accelerates simulated birth trauma-induced stress urinary incontinence recovery in rats.
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
The essential role of PRAK in tumor metastasis and its therapeutic potential.
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Lenvatinib Induces AKT/NF-κB Inactivation, Apoptosis Signal Transduction and Growth Inhibition of Non-small Cell Lung Cancer In Vivo.
Quercetin inhibits invasion and angiogenesis of esophageal cancer cells.
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3β/ZEB1 pathway.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Anti-tumor effects of Solanum nigrum L. extraction on C6 high-grade glioma.
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway.
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
Abiotic Mimic of Matrix Metalloproteinase-9 Inhibitor against Advanced Metastatic Cancer.
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2.
YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Expression of matrix metalloproteinases during axonal regeneration in the goldfish spinal cord.
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway.
Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway.
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
The protective effect of HOXA5 on carotid atherosclerosis occurs by modulating the vascular smooth muscle cell phenotype.
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Curcumol inhibits the viability and invasion of colorectal cancer cells via miR-30a-5p and Hippo signaling pathway.
Effects of blood oxygen saturation on pulmonary artery remodeling in an in vitro perfusion circuit model.
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model.
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Morusin Inhibits Human Osteosarcoma via the PI3K-AKT Signaling Pathway.
Overexpression of miR-29a-3p Suppresses Proliferation, Migration, and Invasion of Vascular Smooth Muscle Cells in Atherosclerosis via Targeting TNFRSF1A.
Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells.
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Overexpression of TEM8 promotes ovarian cancer progression via Rac1/Cdc42/JNK and MEK/ERK/STAT3 signaling pathways.
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway.
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer.
Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway.
Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer.
Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions.
Ziyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells.
Dysfunction of pulmonary epithelial tight junction induced by silicon dioxide nanoparticles via the ROS/ERK pathway and protein degradation.
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Activation of calcium‑sensing receptor‑mediated autophagy in high glucose‑induced cardiac fibrosis in vitro.
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells.
ERK/AKT Inactivation and Apoptosis Induction Associate With Quetiapine-inhibited Cell Survival and Invasion in Hepatocellular Carcinoma Cells.
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Elastophagocytosis and interstitial granulomatous infiltrate are more common in extragenital vs genital lichen sclerosus.
Lactate induced up-regulation of KLHDC8A (Kelch domain-containing 8A) contributes to the proliferation, migration and apoptosis of human glioma cells.
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p.
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Insulin-like growth factor-binding protein 3 inhibits angiotensin II-induced aortic smooth muscle cell phenotypic switch and matrix metalloproteinase expression.
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Wnt/β‑catenin signaling modulates piperine‑mediated antitumor effects on human osteosarcoma cells.
MicroRNA-203 restrains epithelial-mesenchymal transition, invasion and migration of papillary thyroid cancer by downregulating AKT3.
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway.
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.
Long non-coding RNA lnc-DC in dendritic cells regulates trophoblast invasion via p-STAT3-mediated TIMP/MMP expression.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
KLF5 inhibits STAT3 activity and tumor metastasis in prostate cancer by suppressing IGF1 transcription cooperatively with HDAC1.
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity.
Activities of matrix metalloproteinase-2, matrix metalloproteinase-9, and serine proteases in samples of the colorectal mucosa of Miniature Dachshunds with inflammatory colorectal polyps.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.
8‑Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway.
MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
CARLo-5 as an oncogenic gene in endometrial carcinoma.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p.
Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway.
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
Discovery of 9O-Substituted Palmatine Derivatives as a New Class of anti-COL1A1 Agents via Repressing TGF-β1/Smads and JAK1/STAT3 Pathways.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
MiR-126-5p promotes contractile switching of aortic smooth muscle cells by targeting VEPH1 and alleviates Ang II-induced abdominal aortic aneurysm in mice.
Circular RNA circRIMS1 Acts as a Sponge of miR-433-3p to Promote Bladder Cancer Progression by Regulating CCAR1 Expression.
Transplanting Rac1-silenced bone marrow mesenchymal stem cells promote neurological function recovery in TBI mice.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
PRCC-TFE3 regulates migration and invasion of translocation renal cell carcinomas via activation of Drp1-dependent mitochondrial fission.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
MicroRNA-505-3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
MicroRNA-1298-5p inhibits cell proliferation and the invasiveness of bladder cancer cells via down-regulation of connexin 43.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
IκB kinase α: an independent prognostic factor that promotes the migration and invasion of oral squamous cell carcinoma.
Wnt5a is involved in LOX-1 and TLR4 induced host inflammatory response in peri-implantitis.
Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy.
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine.
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice.
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA.
Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
Downregulation of RAI14 inhibits the proliferation and invasion of breast cancer cells.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
Estradiol promotes trophoblast viability and invasion by activating SGK1.
HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.
Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells.
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
MicroRNA-99a-5p alleviates atherosclerosis via regulating Homeobox A1.
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Hyperoside protects against heart failure-induced liver fibrosis in rats.
CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.
Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway.
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Inhibition of perivascular mast cell activation is involved in the atheroprotective effect of rosiglitazone in apolipoprotein E-deficient mice.
Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery.
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation.
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals.
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
miR‑16‑2‑3p inhibits cell proliferation and migration and induces apoptosis by targeting PDPK1 in maxillary primordium mesenchymal cells.
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer.
AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model.
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis.
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells.
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway.
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Amentoflavone Induces Apoptosis and Reduces Expression of Anti-apoptotic and Metastasis-associated Proteins in Bladder Cancer.
Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-β1/Smad2 signaling pathway.
Effect of SEPT6 on the biological behavior of hepatic stellate cells and liver fibrosis in rats and its mechanism.
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2).
NCK1 promotes the angiogenesis of cervical squamous carcinoma via Rac1/PAK1/MMP2 signal pathway.
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Upregulation of fascin-1 is involved in HIF-1α-dependent invasion and migration of hypopharyngeal squamous cell carcinoma.
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice.
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis.
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart.
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
In Vitro Study of Colon Cancer Cell Migration Using E-Jet 3D Printed Cell Culture Platforms.
The relationship between lncRNA PCGEM1 and STAT3 during the occurrence and development of endometrial carcinoma.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Magnolol Induces Apoptosis and Inhibits ERK-modulated Metastatic Potential in Hepatocellular Carcinoma Cells.
Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling.
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Ginkgetin ameliorates experimental atherosclerosis in rats.
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice.
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Anticancer Efficacy of Targeted Shikonin Liposomes Modified with RGD in Breast Cancer Cells.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Interference of Notch 1 inhibits the proliferation and invasion of breast cancer cells: Involvement of the β‑catenin signaling pathway.
PUM1 promotes ovarian cancer proliferation, migration and invasion.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Identification of COL1A1 as an invasion‑related gene in malignant astrocytoma.
Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Fine Particulate Matter (PM(2.5)) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Significance of Vasculogenic Mimicry Formation in Gastric Carcinoma.
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells.
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Mda‑7/IL‑24 induces the differentiation of B cell lymphoma via activation of the P38 mitogen activated protein kinase signaling pathway.
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
BMAL1 facilitates trophoblast migration and invasion via SP1-DNMT1/DAB2IP pathway in recurrent spontaneous abortion.
Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells.
LOX-1 is involved in IL-1β production and extracellular matrix breakdown in dental peri-implantitis.
PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds.
Combination of sonodynamic with temozolomide inhibits C6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing NHE-1 expression.
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation.
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice.
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2.
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
MKL1 links epigenetic activation of MMP2 to ovarian cancer cell migration and invasion.
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis.
MicroRNA-203 inhibits proliferation and invasion, and promotes apoptosis of osteosarcoma cells by targeting Runt-related transcription factor 2.
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy.
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.
Effects of quercetin on proliferation and migration of human glioblastoma U251 cells.
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Role of the lncRNA ABHD11-AS(1) in the tumorigenesis and progression of epithelial ovarian cancer through targeted regulation of RhoC.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Dynamics of MMP‑9, MMP‑2 and TIMP‑1 in a rat model of brain injury combined with traumatic heterotopic ossification.
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
HOX Antisense lincRNA HOXA-AS2 Promotes Tumorigenesis of Hepatocellular Carcinoma.
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells.
Nanoparticle-mediated arresten gene inhibits neointimal formation of vein grafts: an experimental research.
Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling.
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
Yes-Associated Protein Contributes to the Development of Human Cutaneous Squamous Cell Carcinoma via Activation of RAS.
Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing.
MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Elevated Expression of Matrix Metalloproteinase-9 not Matrix Metalloproteinase-2 Contributes to Progression of Extracranial Arteriovenous Malformation.
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Low-dose UVB irradiation prevents MMP2-induced skin hyperplasia by inhibiting inflammation and ROS.
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice.
Plasma miR-185 is decreased in patients with esophageal squamous cell carcinoma and might suppress tumor migration and invasion by targeting RAGE.
ENaC mediates human extravillous trophblast cell line (HTR8/SVneo) invasion by regulating levels of matrix metalloproteinase 2 (MMP2).
miR-29c suppresses pancreatic cancer liver metastasis in an orthotopic implantation model in nude mice and affects survival in pancreatic cancer patients.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
The Notch pathway mediates the angiotensin II-induced synthesis of extracellular matrix components in podocytes.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Potent effects of dioscin against liver fibrosis.
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer.
α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway.
Human umbilical cord mesenchymal stem cells promote carcinoma growth and lymph node metastasis when co-injected with esophageal carcinoma cells in nude mice.
Effects of reduced β2-glycoprotein I on the expression of aortic matrix metalloproteinases and tissue inhibitor matrix metalloproteinases in diabetic mice.
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway.
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries.
Rho GDP dissociation inhibitor beta promotes cell proliferation and invasion by modulating the AKT pathway in hepatocellular carcinoma.
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
The use of MMP2 antibody-conjugated cationic microbubble to target the ischemic myocardium, enhance Timp3 gene transfection and improve cardiac function.
Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression.
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19.
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Inhibition of cell migration by ouabain in the A549 human lung cancer cell line.
Effects of stable knockdown of Aurora kinase A on proliferation, migration, chromosomal instability, and expression of focal adhesion kinase and matrix metalloproteinase-2 in HEp-2 cells.
Cai D, Zhu C, Huang H, Cao Y, Cai G, Chen Z, Feng J, Zhang W, Mao W, Lai J
Research (Washington, D.C.) 2026;9:1016
Research (Washington, D.C.) 2026;9:1016
Identification of Inhibitors for eIF5A2-Dependent Translation Elongation by Monitoring the Translational Efficiency of Polyproline Motif in Mitochondrial Fission Regulator 1.
Suzuki M, Komeno M, Yasumura R, Miwa A, Enomoto M, Kotani H, Matsumoto K, Akimoto K, Takahashi C, Igarashi K, Higashi K
Biological & pharmaceutical bulletin 2026;49(2):355-363
Biological & pharmaceutical bulletin 2026;49(2):355-363
Versatile Nanotherapeutics for Enhancing Sonodynamic Therapy/Chemotherapy of Thyroid Cancer through Remodeling Tumor Microenvironment and Synergistic Reactive Oxygen Species Augment.
Wang D, Sun L, Wang J, Wang L, Wang Z, Zhang Y, Zhou Q, Chen Y, Jiang J
Biomaterials research 2026;30:0338
Biomaterials research 2026;30:0338
An Injectable Photothermal Responsive Liposome Hydrogel Co-Loaded with Bufalin, Apatinib, and IR820 for Inhibiting Postoperative Recurrence of Colon Cancer.
Wang AJ, Tian H, Wang ZP, Cheng JX, Sun J, Zhao F, Shi YJ, Zhang XF, Zou JB, Luan F, Zhai BT, Guo DY
International journal of nanomedicine 2026;21:575430
International journal of nanomedicine 2026;21:575430
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Shao C, Sun Y, Zhao J, Ju C, Yang T, Liu J, Zhou L, Jia R, Zhao F
Stem cells international 2026;2026:3343152
Stem cells international 2026;2026:3343152
Targeting the LINC01515/miR-325-3p/ERBB4 axis suppresses gastric cancer progression.
Ji Q, Tan B, Li F, Liu W, Zhao Y, Yuan X, Hua K, Chen Z, Fan L, Zhao Q, Li Y
American journal of translational research 2026;18(1):524-536
American journal of translational research 2026;18(1):524-536
Injectable Cu(2+) loaded rhein hydrogel for cross-amplifying osteosarcoma apoptosis and cuproptosis epitranscriptomically.
Zhu J, Zhou T, Tang X, Gao Y, Teng Q, Zhang Y, Lv Z, Chen X, Zou J, Shi H
Biomaterials 2026 Sep;332:124170
Biomaterials 2026 Sep;332:124170
Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation.
Li C, Yang L, Zhang Y, Zhao B, Qu H
Oncology reports 2026 May;55(5)
Oncology reports 2026 May;55(5)
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression.
Deng C, Cai S, Guo C, Khan S, Liu L, Tian Q, Ma Z, Zhang J, Zhao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e20917
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e20917
TSG101 Promotes SIAH1 Auto-Ubiquitination to Drive Migration and Invasion in Hepatocellular Carcinoma Cells.
Qiu J, Gu X, Wu K, Wu J, Xu C, Shan W, Shi H
Journal of cellular and molecular medicine 2026 Mar;30(6):e71109
Journal of cellular and molecular medicine 2026 Mar;30(6):e71109
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Li H, Qian L, Ji Y, Geng Y, Lu Y, Zhang L, Xu Y, Zong W, Jiang X, Zhou X, Wen J, Liu D, Wang Y, Li Y, Li B, Ma H, Yu D
Cell death & disease 2026 Mar 9;17(1)
Cell death & disease 2026 Mar 9;17(1)
Inhibition of CDC20 suppresses the development and progression of mantle cell lymphoma through PI3K/AKT pathway.
Chen Y, Yang P, Gao S, Liu S, Wang J, Zhang W, Jing H
Annals of hematology 2026 Mar 9;105(4)
Annals of hematology 2026 Mar 9;105(4)
Cellular Effects and Regulated Protein Expression of MCF-7 Breast Cancer Cells Following Exposure to PAH Derivative 3-Hydroxybenz[a]anthracene.
Kang X, Song W, Li X, Yang Y, Wu X
Toxics 2026 Mar 4;14(3)
Toxics 2026 Mar 4;14(3)
Polystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism.
Huang X, Xu L, Wang J, Cheng J, Yuan J, Liu X, Larionova I, Kzhyshkowska J, Chen S, Zhao Y
Cell death discovery 2026 Mar 26;12(1)
Cell death discovery 2026 Mar 26;12(1)
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Dong T, Jiang Y, Ye F, Zhao B, Xi F, Lv M, Yang M, Pu Y, Jiang P, Luo Q
Placenta 2026 Mar 25;176:76-86
Placenta 2026 Mar 25;176:76-86
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
Lin M, Zhou Y, Wang Y, Yan H, Qin X, Zhong X, Yang G, Liu Q
Biochemical genetics 2026 Mar 25;
Biochemical genetics 2026 Mar 25;
Hedyotis diffusa and Scutellaria barbata enhance the anti-ovarian cancer effect of cisplatin through network pharmacology analysis and molecular docking technology.
Bi R, Chen F, Fu Y, Guo C, Li W
Scientific reports 2026 Mar 17;16(1)
Scientific reports 2026 Mar 17;16(1)
Nicotine Activates PI3K/AKT Pathway to Induce Cellular Proliferation, Invasion, and Migration in HPV-16 Positive Cervical Cancer SiHa Cells.
Wang J, Hu Y, Gong J, Chen L, Zhang L, Wang H
Journal of applied toxicology : JAT 2026 Jun;46(6):2077-2089
Journal of applied toxicology : JAT 2026 Jun;46(6):2077-2089
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
Du X, Li SY, Wu GL, Cai HY, Sun CY, Lin H, Cai YF, Wang Q
Rejuvenation research 2026 Jun;29(3):131-145
Rejuvenation research 2026 Jun;29(3):131-145
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Qi W, Wang J, Wang Y, Cui J, Wu X, Ding Z, Jiang T, Liu W, Zhai X, Jin S, Ye L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Paeoniflorin suppresses the phenotypic transformation of vascular smooth muscle cells during atherosclerosis by regulating the MAPK/NF-κB pathways and ABCA1 expression.
Zhang Y, Sun L, Li F, Li Y, Zhou Q
Cellular signalling 2026 Jul;143:112477
Cellular signalling 2026 Jul;143:112477
The microbial metabolite isovaleric acid aggravates gelatinase-mediated periodontal tissue destruction via the NF-κB signaling pathway.
Zheng H, Tu Y, Ning X, Guo Q, Ren B, Xie J, Liu C
Journal of periodontology 2026 Jan;97(1):97-110
Journal of periodontology 2026 Jan;97(1):97-110
piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization.
Shi Y, Sun J, Yu K, Lu D, Niu X, Li Y, Huang S, Luo J, Wang X, Ma X, Li J, Ying Y, Xie L, Liu B
Translational oncology 2026 Jan;63:102626
Translational oncology 2026 Jan;63:102626
Enhanced anti-tumor efficacy of prNK-lysin delivered by injectable pH-responsive hydrogel in the treatment of orthotopic breast cancer.
Cheng X, Fan K, Zhou Y, Haseeb A, Noor F, Sun N, Yin W, Sun P, Zhang H, Yang H, Zhang Z, Shen S, Li H
International journal of biological macromolecules 2026 Jan;338(Pt 2):149754
International journal of biological macromolecules 2026 Jan;338(Pt 2):149754
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
Shi Y, Song Y, Wang T, Jiao Y, Dang J, Zhang Y, Xiao S, Song B, Yu Z
Pathology, research and practice 2026 Jan;277:156311
Pathology, research and practice 2026 Jan;277:156311
MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
Pan T, Zhu J, Wang X, Tang D, Wang Z, Yang Y, Teng Y, Tian Q, Dan G, Chen C, Yu D, Liu M, Wang H, Zhang T, Guo B, Chen T, Jin B
Cancer research 2026 Jan 2;86(1):146-166
Cancer research 2026 Jan 2;86(1):146-166
IL-36 participated in airway remodeling in chronic asthma model by inducing epithelial-mesenchymal transition process.
Zhang M, Cen J, Gan W, Feng K, Yang H, Zou X, Li H, Zhang T
European journal of medical research 2026 Jan 15;31(1):225
European journal of medical research 2026 Jan 15;31(1):225
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
Wang M, Liu C, Li Z, Wang Y, Li Y, Pei F
Scientific reports 2026 Jan 13;16(1):4621
Scientific reports 2026 Jan 13;16(1):4621
Buspirone hydrochloride: a potential regulator of PD-L1 for enhanced antitumor activity in melanoma-bearing mice.
Geng J, Wang K, Zhang S, Cheng X, Zhang C, Mo M, Ji X, Shao M, Jiang H, Lei M, Guo S, Yang Z, Zhang Y, Wei T, Tian Z, Ji Y, Zhao T, Jia H
Journal of drug targeting 2026 Jan 12;:1-14
Journal of drug targeting 2026 Jan 12;:1-14
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
Li L, Dan M, Li S, Cui X, Bao S, Luo S, Cao J
Toxicology 2026 Feb;520:154368
Toxicology 2026 Feb;520:154368
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
Liu H, Su PW, Song H, Wang C, Shan P, Zhang H
Chemistry & biodiversity 2026 Feb;23(2):e02436
Chemistry & biodiversity 2026 Feb;23(2):e02436
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
Ding Y, Wang Z, Xia X, Wang J, Li Z, Gu C, Hao C, Xu K, Gao M, Yin H, Chen S, Gong X, Zhou W, Zhang M, Yang Y, Zhang D, Dai B, Zhang M
European journal of medicinal chemistry 2026 Feb 5;303:118471
European journal of medicinal chemistry 2026 Feb 5;303:118471
SERPINA4 facilitates colorectal cancer progression through m⁶A-dependent stabilization.
Zhang X, Liu Y, Tu Q, Zhang D, Deng J, Zhou J, Lv H, Zhou J, Qiu F, Deng Y
Journal of translational medicine 2026 Feb 28;24(1)
Journal of translational medicine 2026 Feb 28;24(1)
Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8.
Takasaki-Kawasaki H, Sato S, Tamehisa T, Yoneda T, Shiroshita A, Fujimura T, Tamura I, Maekawa R, Sugino N
Scientific reports 2026 Feb 27;16(1)
Scientific reports 2026 Feb 27;16(1)
Discovery of Novel Snail Inhibitors Derived from Omeprazole for Antiatherosclerotic Therapy: A Structure-Based Approach.
Zeng Z, Lu Y, Fang M, Guo X, Zhong W, Xiong G, Wang Y, Sun F, Xu J, Wu Z, Fu R, Liu J
Journal of medicinal chemistry 2026 Feb 26;69(4):5002-5023
Journal of medicinal chemistry 2026 Feb 26;69(4):5002-5023
DNMT3b promotes proliferation and invasion by mediating HOPX DNA methylation in lung cancer.
Guan K, Zhao S, Zhang G, Wang Y, Song D, Ding Y
iScience 2026 Feb 20;29(2):114347
iScience 2026 Feb 20;29(2):114347
Fluoxetine suppresses triple-negative breast cancer progression by inducing apoptosis, inhibiting Src-mediated invasiveness, and enhancing anti-tumor immunity.
Wu HJ, Weng YS, Liu YC, Wei YT, Li PY, Lee PY, Hsu FT
Molecular medicine (Cambridge, Mass.) 2026 Feb 17;32(1)
Molecular medicine (Cambridge, Mass.) 2026 Feb 17;32(1)
S100A10 promotes glycolysis and malignant progression of CCA by activating the HK2/ERK signaling pathway.
Wang Y, Chen W, Liu W, Zhang X, Wang Y, Dai N
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Feb 17;
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Feb 17;
LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism.
Zhao F, Yang S, He T, Yang L, Mo T, Kang J, Cao H, Sun X, Yu Y
Scientific reports 2026 Feb 16;16(1)
Scientific reports 2026 Feb 16;16(1)
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275
Free radical biology & medicine 2026 Feb 1;243:260-275
Rabdosin B suppresses proliferation of nonsmall cell lung cancer by regulating the SRC/PI3K/AKT signaling pathway.
Chen X, Hao J, Guo C, Zhang J, Lv L, Peng Y, Li N, Xie Q, Wang X, Chen H, Zhang Y
Pharmaceutical biology 2026 Dec;64(1):451-470
Pharmaceutical biology 2026 Dec;64(1):451-470
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
Liu L, Gao M, He W, Wang M, Zhou S, Wang X, Shu Y
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
Yang Z, Wei W, Nie D, Zhang M, Chen Q
Future science OA 2026 Dec;12(1):2615619
Future science OA 2026 Dec;12(1):2615619
Hyodeoxycholic acid relieves neuropathic pain by activating farnesoid X receptor signaling.
Lin J, Zeng X, Su Z, Li X, Yu Y, Qian S, Hou Q, Duan W, Wang Z, Liu C, Zhang J, Huang C, Liao L
Journal of advanced research 2026 Apr;82:881-900
Journal of advanced research 2026 Apr;82:881-900
TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.
Weiden EM, Serianz Z, Klingl Y, Jörs S, Jaślan D, Keller M, Castro SP, Mkhitaryan M, Jeridi A, Briukhovetska D, Spix B, Scotto Rosato A, Agami A, Schiller HB, Rajan S, Schredelseker J, Fois G, Frick M, Kobold S, Klein M, Geisler F, Garcia-Fortanet J, Murphy LO, Bracher F, Wahl-Schott C, Gudermann T, Dietrich A, Biel M, Yildirim AÖ, Grimm C
The EMBO journal 2026 Apr;45(7):2182-2209
The EMBO journal 2026 Apr;45(7):2182-2209
AKAP2 is required for assembly of cytoskeletal signaling complexes that promote growth and metastasis of triple-negative breast cancer.
Rosenthal KJ, Felix-Sanchez P, Forbush K, Rhoads N, Kang M, Vicente JJ, Smith FD, Wordeman L, Ong SE, Cheung KJ, Scott JD
The Journal of biological chemistry 2026 Apr;302(4):111329
The Journal of biological chemistry 2026 Apr;302(4):111329
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Chen MH, Hua YJ, Li Y, Lei Y, Zhou SY, Hu XD, Hu DH, Dong ZH, Lu Y, Zhuang T, Ruan CC
Nature immunology 2026 Apr;27(4):738-749
Nature immunology 2026 Apr;27(4):738-749
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
Li H, Zhao R, Wan L, Yuan Y, Ma E, Li Y, Chen Z, Liu B, Song Y, Cao Z, Jiao X, Wang Y, Wu P, Jin H, Li J, Yang X, Huang L, Zhang Y, Yang K, Huo J, Jin H, Zhong H, Min M, Zhang S, Cao Y, Li W, Zhang R, Wei C
Nature aging 2026 Apr 6;
Nature aging 2026 Apr 6;
Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis.
Li BB, Zhang JT, Jiang YY, Li X, Wang DN, Zang JM, Liu ZL, Hu FX, Zhu X, Shen CC, Zhang W, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 19;156:158220
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 19;156:158220
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.
Wang Y, Wang J, Chang Z
Applied biochemistry and biotechnology 2026 Apr 17;
Applied biochemistry and biotechnology 2026 Apr 17;
Structure-based discovery of a novel allosteric activator of ATG4B for the treatment of triple-negative breast cancer.
Jin W, Li Z, Li Z, Song J, Liu H, Liu Q, Gao F, Zhang L
European journal of medicinal chemistry 2026 Apr 15;308:118686
European journal of medicinal chemistry 2026 Apr 15;308:118686
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Zhang H, Chang Y, Fu Q, Jin T, Zhang S, Zhang M
International immunopharmacology 2026 Apr 15;175:116417
International immunopharmacology 2026 Apr 15;175:116417
Tributyl phosphate as a type of environmental endocrine disruptor associated with liver fibrosis: insights from NHANES and in vitro validation.
Yang L, Ju A, Huang Y, Jiang H, Ye J, Qi W, Zhou L
Frontiers in toxicology 2025;7:1623830
Frontiers in toxicology 2025;7:1623830
Sono-Gas-Mediated Precise Stiffness Remodeling for Triple-Negative Breast Cancer Mechanical Immunotherapy.
Hu Y, Cheng L, Guo X, Zheng M, Zhang W, Wang X, Tang R, Chen Q, Guo Y, Cao Y, Wang Z, Ran H
Biomaterials research 2025;29:0207
Biomaterials research 2025;29:0207
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression.
He HF, Hou S, Ma XY, Huang SS, Yang B, Wang JK, Xu Y, Tan L, Li HY
PloS one 2025;20(4):e0319605
PloS one 2025;20(4):e0319605
Lathyrol affects the expression of AR and PSA and inhibits the malignant behavior of RCC cells.
Song S, Tai L, Zhou L, Jiang J, Zhao J
Open medicine (Warsaw, Poland) 2025;20(1):20241136
Open medicine (Warsaw, Poland) 2025;20(1):20241136
Association between TGF-β1 and β-catenin expression in the vaginal wall of patients with pelvic organ prolapse.
Xue FQ, Xu D, Zhao SR, Ma Y, Zhao Y
Open life sciences 2025;20(1):20221058
Open life sciences 2025;20(1):20221058
Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor.
Chen YN, Xiu JY, Zhao HQ, Luo JT, Yang Q, Li Y, Wei WB
International journal of ophthalmology 2025;18(5):765-778
International journal of ophthalmology 2025;18(5):765-778
Catalpol Alleviates HFpEF via Inhibition of the S100A8-RAGE-NOX4 Inflammatory Axis in Murine Hearts.
Cao Y, Li S, Zhang Y, He M, Shen Y
Journal of inflammation research 2025;18:17143-17161
Journal of inflammation research 2025;18:17143-17161
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
Yuan Q, Jiang H, Zhu M, Chu Y, Zhang Y, Bie J, Li L
Journal of Cancer 2025;16(3):765-783
Journal of Cancer 2025;16(3):765-783
Longikaurin A, a natural ent-kaurane, suppresses proliferation, invasion and tumorigenicity in oral squamous cell carcinoma cell by via inhibiting PI3K/Akt pathway in vitro and in vivo.
Luo Y, Wang Z, Li Y, Zhang L
Journal of Cancer 2025;16(3):708-719
Journal of Cancer 2025;16(3):708-719
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Wang J, Wang C, Jia Y, Chen F, Wang Y, Du J
Frontiers in pharmacology 2025;16:1654108
Frontiers in pharmacology 2025;16:1654108
HMGA2 interacts with KAT6A to regulate MMPs chromatin architecture and promote triple-negative breast cancer metastasis.
Qiao L, Liang Z, Ma P, Zhang S, Sun C, Luo W, Yu L
Frontiers in immunology 2025;16:1590368
Frontiers in immunology 2025;16:1590368
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
Ge H, Du Z, Liu W, Wang L, Li J, Yang G, Li A
Frontiers in pharmacology 2025;16:1578877
Frontiers in pharmacology 2025;16:1578877
TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts.
Mi B, Li C
Frontiers in immunology 2025;16:1558881
Frontiers in immunology 2025;16:1558881
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583
Theranostics 2025;15(15):7567-7583
LncRNA BANCR/miR-15a/MAPK1 Induces Apoptosis and Increases Proliferation of Vascular Smooth Muscle Cells in Aortic Dissection by Enhancing MMP2 Expression.
Zheng Z, Wang W, Chen B, Huang M, Wang T, Xu Z, Dai X
Cell biochemistry and biophysics 2025 Sep;83(3):3581-3596
Cell biochemistry and biophysics 2025 Sep;83(3):3581-3596
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
Jin S, Wu Q, Chang S, Zeng S, Yin J, Ma H
Electrophoresis 2025 Sep;46(18):1388-1396
Electrophoresis 2025 Sep;46(18):1388-1396
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Zhang B, Yu C, Zhang S, Zhang M
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Ubiquitin-specific protease 7-mediated stabilization of discoidin domain receptor 1 drives progression of TP53-Mutant cancers.
Xue Y, Xiu B, Yang M, Zhang Y, Yang C, Zhang L, Yan Y, Luo X, Huang Y, Mei H, Li G, Zhou L, Chen Y, Zhang W, Qian C, Zhang P, Liu J, Liang A, Zeng Y, Yang J
The Journal of biological chemistry 2025 Sep;301(9):110515
The Journal of biological chemistry 2025 Sep;301(9):110515
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Xia W, Yao H, Mu T, Liu H, Chen J, Feng S, Wen S
Experimental and therapeutic medicine 2025 Sep;30(3):167
Experimental and therapeutic medicine 2025 Sep;30(3):167
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
Lv L, Che D, Zhang Z, Zhang W, Zhou Q, Li F, Zhou J
Experimental eye research 2025 Sep;258:110485
Experimental eye research 2025 Sep;258:110485
HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion.
Pessa JC, Paavolainen O, Hästbacka HSE, Puustinen MC, Da Silva AJ, Pihlström S, Gramolelli S, Boström P, Hartiala P, Peuhu E, Joutsen J, Sistonen L
Science advances 2025 Sep 5;11(36):eady1289
Science advances 2025 Sep 5;11(36):eady1289
Microenvironment-driven transformable self-assembly nanoplatform enables spatiotemporal remodeling for rheumatoid arthritis therapy.
Hu C, Ma J, Chen X, Chen Y, Song Y, Tang Q, He X, Wang Y, Gao H, Zhang J
Science advances 2025 Sep 5;11(36):eadu5245
Science advances 2025 Sep 5;11(36):eadu5245
NGAL knockdown alleviated CSE-induced cellular senescence and reduced MMP2 and MMP9 expression in alveolar macrophages through the PI3K/Akt pathway.
Wang Y, Jin C, Zheng Y, Wang J
European journal of medical research 2025 Sep 23;30(1):850
European journal of medical research 2025 Sep 23;30(1):850
KLF9 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Regulating Ceramide Synthase 1 Synthesis.
He Y, Pan J, Chen S, Lin Y, She P, Chen Y, Xu N, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70954
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70954
JunB orchestrates macrophage-fibroblast crosstalk in silica nanoparticle-induced pulmonary fibrosis.
Li F, Song D, Meng J, Tian J, Li N, Zheng Y, Zhang Z, Yun X, Li Z, Sun H, Zhang L, Shen F
Ecotoxicology and environmental safety 2025 Sep 15;303:119046
Ecotoxicology and environmental safety 2025 Sep 15;303:119046
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC-MS, network pharmacology, molecular docking, and experimental validation.
Liu G, Kuang S, Zhong W, Yang A, Huang X, Xie Y, Zhang X, Li Y, Qin Q, Liu G
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Journal of pharmaceutical and biomedical analysis 2025 Sep 15;263:116899
Bushen Jiangu decoction alleviates osteoporosis by inhibiting MMP2 expression and activation of the MAPK pathway in vitro.
Chen P, Lin J
Tissue & cell 2025 Oct;96:103025
Tissue & cell 2025 Oct;96:103025
Cationic microbubble loading hSIRT3 and hTIMP3 optimize cardiac-targeted delivery and myocardial protection in the porcine MI/R model.
Cai P, Chen K, Qin X, Jiang X, Jiao X, Liu K, Guo E, Li Z, Qiu X, Liu C, Sun L, Chuai J, Wu J, Chen W, Tian H
Materials today. Bio 2025 Oct;34:102234
Materials today. Bio 2025 Oct;34:102234
A dual-functional mitochondrial probe for melanoma visualization and PI3K/AKT/mTOR-EMT signaling axis-mediated antitumor therapy.
Xia T, Liao H, Zeng Z, Li M, Yang S, Yang X, He Y, Qing J, Liu L, Xiong X, Sun C
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114847
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114847
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
Liu YJ, Song HX, Li JH, Wang XY, Nie XF, Zhang LN
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
Selection and identification of a novel DNA aptamer for recognizing colorectal cancer stem cells.
Li W, Bing T, Wang Q, Li Y, Sun S, Li X, Ma Y, Wang R, Ba W, Li X, Shangguan D, Fang J
Bioorganic chemistry 2025 Oct;165:108989
Bioorganic chemistry 2025 Oct;165:108989
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
Li JH, Wang XY, Song HX, Nie XF, Zhang LN
Biomolecules 2025 Oct 7;15(10)
Biomolecules 2025 Oct 7;15(10)
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
Li H, Ouyang J, Zhang Y, Zhang Z, Sun M, Liu R, Qian C
Scientific reports 2025 Oct 29;15(1):37897
Scientific reports 2025 Oct 29;15(1):37897
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
Li J, Tang H, Chang H, Du Y, Du L, Zhao E
Cell death & disease 2025 Oct 21;16(1):737
Cell death & disease 2025 Oct 21;16(1):737
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
Zhao Q, Wu J, Yao J, Liu Z, Li C, Sun Q
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
Salvigenin inhibits gastric cancer progression by suppressing the EGFR/PI3K/AKT pathway.
Qiao K, Yang Z, Fang Y, Fang C
Biochemical and biophysical research communications 2025 Oct 10;784:152645
Biochemical and biophysical research communications 2025 Oct 10;784:152645
An integrative bioinformatics approach unveils fibrosis-driven prognostic signature and immunotherapeutic potential in kidney renal clear cell carcinoma.
Lai J, Chen Z, Wu W
Toxicology and applied pharmacology 2025 Nov;504:117533
Toxicology and applied pharmacology 2025 Nov;504:117533
Selection and characterization of novel DNA aptamers targeting colorectal cancer cells with malignant potential.
Ma Y, Wang Q, Sun S, Li Y, Wang R, Yang H, Wang D, Hao Y, Tong Y, Li W
Analytical and bioanalytical chemistry 2025 Nov;417(26):5941-5955
Analytical and bioanalytical chemistry 2025 Nov;417(26):5941-5955
Bone morphogenetic protein 1 as a macromolecular pan-cancer biomarker modulating the immune microenvironment and malignant phenotypes in glioblastoma.
Yu Z, Hu F, Nie C, Fang X, Shen Y, Shang R, Liu H, Zhou Q, Zhang H, Gao A, Liang H
International journal of biological macromolecules 2025 Nov;331(Pt 1):148136
International journal of biological macromolecules 2025 Nov;331(Pt 1):148136
LncRNA LINC01605 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection Through Regulating SGK1.
Li M, Li R, Zheng Z, Xiao C, Yang Q, Chen B, Dai X
Journal of cellular and molecular medicine 2025 Nov;29(22):e70963
Journal of cellular and molecular medicine 2025 Nov;29(22):e70963
GCN2 promotes fatty acid metabolism through the activation of PI3K/AKT signaling in gastric cancer.
Sun D, Sun X, Wang X, Zhang J, Liu L, Xie J
Cellular signalling 2025 Nov;135:111984
Cellular signalling 2025 Nov;135:111984
KLK1 as an Epithelial-Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R-Mediated Fibroblast Phenotypic Transition.
Zhou L, Wang M, Liu S, Gu L, Liu S, Du Q, Zhang T, Ma Y, Zhao L, Wang J, Xu Q, Ling T, Cheng H, Chen H, Sun Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e07063
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e07063
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Long T, Li X, Zhou Y, Zhu C, Zhang M, Li M, Wei Z
Gene 2025 Nov 5;971:149800
Gene 2025 Nov 5;971:149800
BRG1 Ablation in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm: Mechanism and Translational Potential.
Li N, Xue Y, Zhang Q, Xu Y, Xu H, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71199
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71199
Sorting nexin 9 expression and prognostic implications in lung adenocarcinoma: integrative bioinformatic and in vitro validation.
Liu W, Yin Y, Wang B, Li T, Chen J
Translational cancer research 2025 Nov 30;14(11):7480-7493
Translational cancer research 2025 Nov 30;14(11):7480-7493
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Gong S, Xu Y, Zhao R, Yu J, Bao L, Zhang Y, Li F, Jiao L, Kou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
Li J, Cui H, Sun X, Zhu L, Li J, Liu R, Li Z
International immunopharmacology 2025 Nov 14;165:115509
International immunopharmacology 2025 Nov 14;165:115509
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
Li N, Zhang R, Zhao XX, Zhou L, Li YL, Cui ZG, Zheng HC
International immunopharmacology 2025 Nov 14;165:115445
International immunopharmacology 2025 Nov 14;165:115445
Targeting the p38/MAPK pathway to induce apoptosis: a multidimensional mechanistic exploration of Mentha and its active compound diosmetin against liver cancer.
Song Y, Du Y, Li W, Fan Y, Zhang Y, Shen H, Cheng L, Wang J, Deng F, Tang B
Scientific reports 2025 Nov 11;15(1):39432
Scientific reports 2025 Nov 11;15(1):39432
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Zhang L, Ou X, Wang Q, Shi S
Journal of translational medicine 2025 Nov 10;23(1):1249
Journal of translational medicine 2025 Nov 10;23(1):1249
Precision hyperthermia-induced HSP20 inhibits gastric cancer cell invasion, migration, and proliferation.
Sun Q, Long Z, Wang Y, Ren J, Wang D
Discover oncology 2025 Nov 10;16(1):2070
Discover oncology 2025 Nov 10;16(1):2070
Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD.
Jung U, Wei E, Ahsan H, Mitanoska A, Chen K, Kyba M, Bosnakovski D
JCI insight 2025 Nov 10;10(21)
JCI insight 2025 Nov 10;10(21)
Methylparaben and propylparaben promote bladder cancer invasion via MMP2 and PPARG modulation.
Zhu T, Luo W, Zhang Y, Liang Z, Wu S, Yang C, Zhou R, Tan W, Liu C
Ecotoxicology and environmental safety 2025 Nov 1;306:119383
Ecotoxicology and environmental safety 2025 Nov 1;306:119383
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
METTL1 Enhances RRP9 mRNA Stability Through m7G Modification to Drive Colorectal Tumorigenesis.
Li N, Jing Y, Xu L, Wang M
Molecular carcinogenesis 2025 May;64(5):858-869
Molecular carcinogenesis 2025 May;64(5):858-869
Cohesin Complex Interacting with Promoters of MMP Genes for in Pterygium Occurrence.
Han S, Zhu W, Guo Q
Current eye research 2025 May;50(5):467-476
Current eye research 2025 May;50(5):467-476
RBM15-mediated the m6A modification of MAT2A promotes osteosarcoma cell proliferation, metastasis and suppresses ferroptosis.
Huang Z, Chen P, Liu Y
Molecular and cellular biochemistry 2025 May;480(5):2923-2933
Molecular and cellular biochemistry 2025 May;480(5):2923-2933
RTA activates the activity of the miR-155 promoter region and promotes the growth and invasion of endothelial cells through the regulatory network of miR-155/GATA3/STAT3.
Pan Y, Zheng J, Ren Z, Yuan W, Zhao J, Zheng C, Zeng Y
International journal of biological macromolecules 2025 May;310(Pt 4):143536
International journal of biological macromolecules 2025 May;310(Pt 4):143536
lncRNA ZNF667‑AS1 inhibits ovarian cancer progression by interacting with the TNF signaling pathway.
Wu F, Zhang T, Mei X, Gao T
Experimental and therapeutic medicine 2025 May;29(5):100
Experimental and therapeutic medicine 2025 May;29(5):100
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Wang J, Du J, Song Y, Tan X, Wu J, Wang T, Shi Y, Xu X, Yu Z, Song B
Cell death & disease 2025 May 9;16(1):371
Cell death & disease 2025 May 9;16(1):371
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Wang JQ, Liu XM, Zhu ZS, Li Z, Xie CZ, Qiao X, Feng YK, Xu JY
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Gao Z, Yu X, Su W, Huang P, Li Z, Lin Y, Chen LL, Cao Y, Liu Y, Chen J, Yang D, Cao G
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
Wang Z, He K, Liu M, Lv W, Cheng B, Zhang G, Wang X, Zeng M, Jiao L, Han S, Zheng Y, Feng Z
Cancer letters 2025 May 28;618:217623
Cancer letters 2025 May 28;618:217623
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway.
Wang JM, Zhang FH, Xie HY, Liu ZX, Tang YJ, Shu X, Wu YQ, Lu DH, Sun JZ, Ying YF, Ma XY, Zheng XY, Wang X, Liu B, Li JF, Xie LP, Luo JD
Cell reports 2025 May 27;44(5):115595
Cell reports 2025 May 27;44(5):115595
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
Huang Y, Yang T, Yang C, Tang B, Su B, Yang X
Scientific reports 2025 May 22;15(1):17870
Scientific reports 2025 May 22;15(1):17870
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
Liu L, Wang L, Hao N, Du N, Li Y, Kang S
Gene 2025 May 20;950:149385
Gene 2025 May 20;950:149385
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Zhang M, Hong Y, Yu W, Zhang Y, Shen Y, Cai Z, Jia R, Pang Z, Huang X, Huang Y, Gao X, Liu Y, Qu Y, Yang Q, Zhang X, Zhu A, Ao H
International immunopharmacology 2025 May 16;155:114513
International immunopharmacology 2025 May 16;155:114513
Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway.
Ge J, Dai J, Ji H, Guo J, Shen X, Sun D, Chen Q, Chen P, Ye G, Guo J, Zhang S
Cell death discovery 2025 May 15;11(1):238
Cell death discovery 2025 May 15;11(1):238
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
Zhang J, Li Z, Song X, Cai P, Liu Q
Scientific reports 2025 May 13;15(1):16664
Scientific reports 2025 May 13;15(1):16664
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
Ma X, Zhang B, Yin X, Yang S, Lin Z, Yang Y, Zhou X
Breast cancer research : BCR 2025 May 12;27(1):74
Breast cancer research : BCR 2025 May 12;27(1):74
CKIP-1 inhibits M2 macrophage polarization to suppress the progression of gastric cancer by inactivating JAK/STAT3 signaling.
Xu X, Xu Z, Cai Y, Chen X, Huang C
Cell biochemistry and biophysics 2025 Mar;83(1):1289-1298
Cell biochemistry and biophysics 2025 Mar;83(1):1289-1298
Kidney Gastrin/CCKBR Attenuates Type 2 Diabetes Mellitus by Inhibiting SGLT2-Mediated Glucose Reabsorption through Erk/NF-κB Signaling Pathway.
Zhang X, Zhang Y, Shi Y, Shi D, Niu M, Liu X, Liu X, Yang Z, Wu X
Diabetes & metabolism journal 2025 Mar;49(2):194-209
Diabetes & metabolism journal 2025 Mar;49(2):194-209
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Wang L, Song J, Yang Z, Zhang H, Wang Y, Liu J, Wang S, Shi J, Tong X
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Xu X, Li X, Zhai C, Yao Y, Li X, Ming C, Sun J, Wang H, Mao Y, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Feng X, Ma Y, Zhao Y, Zhao Z, Song Z, Lin L, Wang W
Molecular immunology 2025 Mar;179:94-105
Molecular immunology 2025 Mar;179:94-105
The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer.
Jiang Y, Wang Y, Xue K, Ma J, Xu S, Wang K, Guo P
Cell & bioscience 2025 Mar 7;15(1):33
Cell & bioscience 2025 Mar 7;15(1):33
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Wang Y, Huang J, Song Z, Zhang S, Guo H, Leng Q, Fang N, Ji S, Yang J
Biology direct 2025 Mar 27;20(1):37
Biology direct 2025 Mar 27;20(1):37
Unmodified RNA sequences form unusual stable G-quadruplexes with potential anti-RSV and anti-angiogenesis applications.
Tian RQ, Gao Y, Hu XH, Jia MH, Fu LY, Pan D, Su SF, Shen XC, Xiao CD
Communications biology 2025 Mar 21;8(1):474
Communications biology 2025 Mar 21;8(1):474
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
Zeng H, Guo A, Liu Z, Xiang S, Zheng F
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Niu X, Chang G, Xu N, Li R, Niu B, Mao R, Wang S, Li G, Jiang J, Wang L
ACS nano 2025 Mar 18;19(10):10433-10451
ACS nano 2025 Mar 18;19(10):10433-10451
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Zhang M, Qiu H, Han Z, Ma Y, Hou J, Yuan J, Jia H, Zhou M, Lu H, Wu Y
International journal of pharmaceutics: X 2025 Jun;9:100316
International journal of pharmaceutics: X 2025 Jun;9:100316
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
Yang Y, Liu S, Xiao X
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
Li B, Zhou W, Yu Y, Chen B, Lv Z, Zhang J, Zhang T, Sun S, Zhou L, Wang M
FASEB bioAdvances 2025 Jun;7(6):e70020
FASEB bioAdvances 2025 Jun;7(6):e70020
TSPAN31 Activates Fatty Acid Metabolism and PI3K/AKT Pathway to Promote Tumor Progression in Breast Cancer.
Luo W, Sun Y, Cao L
Molecular carcinogenesis 2025 Jun;64(6):1078-1089
Molecular carcinogenesis 2025 Jun;64(6):1078-1089
Enhancing the antioxidant capacity of Fe single-atom nanozymes through local coordination manipulation for psoriasis treatment.
Xue H, Li Y, Ma X, Zhang Q, Zhu J, Ni X, Qiu J, Li Z, Mu Z
Materials today. Bio 2025 Jun;32:101830
Materials today. Bio 2025 Jun;32:101830
DEP domain‑containing 1 is a prognostic biomarker associated with the cell cycle in gliomas.
Li H, Liu Y, Zhang H, Wang X
Oncology letters 2025 Jun;29(6):276
Oncology letters 2025 Jun;29(6):276
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
Shi Y, Cao Z, Ge L, Lei L, Tao D, Zhong J, Xu D, Geng T, Li X, Li Z, Xing S, Wu X, Wang Z, Li L
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
Network pharmacology and experimental validation reveals the potential therapeutic effects of Polygonum cuspidatum against odontogenic keratocyst.
Yi JR, Zeng B, Liu JF, Man QW
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3):102105
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3):102105
Aerobic Exercise Upregulates Renal-Derived ELABELA to Improve Myocardial Fibrosis by Activating APJ-AMPK-Sirt1 and Inhibiting TGFβ1-Smad2/3 Signaling Pathways in Myocardial Infarction Mice.
Ren W, Xi Y, Ma Y, Duan X, Wang T, Yu M, Qin S, Gong DW, Tian Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70734
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70734
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Cui M, Ding X, Jiang Y, Zhang L, Cao W, Wang Y, Sheng Z, Sun W, Guo A, Gu L, Zhang X, Duan W, Shi L, Zhang B
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Sinomenine Ameliorates Liver Fibrosis by Blocking TGF-β/SMAD and c-JUN Signaling.
Du Y, Bai J, Ma T, Wu Z, Wang P, Zhong X, Fu W, He S
Phytotherapy research : PTR 2025 Jul;39(7):3182-3196
Phytotherapy research : PTR 2025 Jul;39(7):3182-3196
Ethanolic Extract of Atractylodis Rhizoma Ameliorates DSS-Induced Ulcerative Colitis via Improving Intestinal Barrier Function Through the Rho-Associated Kinase/Myosin Light Chain Pathway.
Gao Z, Huang P, Yu X, Dong R, Lin Y, Tu J, Chen L, Cao Y, Liu Y, Yang D, Cao G
Journal of medicinal food 2025 Jul;28(7):694-707
Journal of medicinal food 2025 Jul;28(7):694-707
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
Huang Z, Jiang Q, Zhang Q, Lu N, Rui X, Chen R, Wang Y, Wang Y, Xu X, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
Matrix metalloproteinase-2 as a novel regulator of glucose utilization by adipocytes.
Lempicki MD, Garrigues RJ, Hondros AD, Zeczycki TN, Garcia BL, Cavanagh J, Harris TE, Meher AK
Scientific reports 2025 Jul 7;15(1):24277
Scientific reports 2025 Jul 7;15(1):24277
Ursodeoxycholic acid alleviates aortic aneurysm and dissection through the intestinal farnesoid X receptor/ceramide synthase 2 axis.
Zhang Z, Xie L, Lin X, He J, Xie Y, Li J, Zhuang X, Tang L, Xie R, Wu Q, Qiu Z, Chen L
Communications biology 2025 Jul 5;8(1):1009
Communications biology 2025 Jul 5;8(1):1009
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Hu Q, Chen Q, Yang W, Ren A, Tan J, Huang T
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Lingguizhugan decoction inhibit pulmonary hypertension by regulating macrophage IL-6 secretion via IL-33/ST2 pathway.
Dong Z, Xue Z, Zhang M, Wang L, Lu Q, Zhao H, Wang X, Nie S, Wei J, Yan H, Fan G, Wang Y, Zhu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156822
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156822
Growth Hormone Signaling in Bladder Cancer: Transcriptomic Profiling of Patient Samples and In Vitro Evidence of Therapy Resistance via ABC Transporters and EMT Activation.
Davis E, Caggiano LJ, Munholland H, Basu R, Berryman DE, Kopchick JJ
International journal of molecular sciences 2025 Jul 23;26(15)
International journal of molecular sciences 2025 Jul 23;26(15)
Targeting LINC02320 prevents colorectal cancer growth via GRB7-dependent inhibition of MAPK signaling pathway.
Zhang L, Chen H, Yang Y, Zhao L, Xie H, Li P, Lv X, He L, Liu N, Liu B
Cellular & molecular biology letters 2025 Jul 21;30(1):86
Cellular & molecular biology letters 2025 Jul 21;30(1):86
Qingrehuoxue formula enhances anti-PD-1 immunotherapy in NSCLC by remodeling the tumor immune microenvironment via TREM2 signaling.
Li BB, Jiang YY, Li X, Yu MM, Meng Q, Wang DN, Zang JM, Xu F
BMC complementary medicine and therapies 2025 Jul 16;25(1):270
BMC complementary medicine and therapies 2025 Jul 16;25(1):270
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
Kang Z, Yin S, Han X, Liu X, Peng Y, Jia Q, Fu Z, Li Y, Wu Y, Xiao Z, Li Z, Wang Y, Luo M, Yang X
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
Enhancing the therapeutic efficacy of gemcitabine in bladder cancer through TGF-β1 inhibition and pluronic F-127-based microsphere delivery.
Xiong Y, Li Y, Chen L, Chen M, He W, Qi L
Journal of biological engineering 2025 Jul 11;19(1):62
Journal of biological engineering 2025 Jul 11;19(1):62
Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction.
Ye Y, Shen F, Yan M, Zhan C, Lv J, Zou M, Wang Z, Ning S, Gao Y, Wu J, Li W
Cell death & disease 2025 Jul 10;16(1):509
Cell death & disease 2025 Jul 10;16(1):509
THBS4 downregulation alters trophoblast function in preeclampsia via the TGF-β1/Smad signaling cascade.
Shi H, Mao Y, Cui J, Ma R, Yang Z, Zhao Y
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C170-C182
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C170-C182
Tea polyphenols nanoparticles integrated with microneedles multifunctionally boost 5-aminolevulinic acid photodynamic therapy for skin cancer.
Wang Y, Fu S, Zeng Y, Jiao S, Chai G, Xu Y
Journal of colloid and interface science 2025 Jan;677(Pt A):446-458
Journal of colloid and interface science 2025 Jan;677(Pt A):446-458
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
Liang H, Zhang C, Hu M, Hu F, Wang S, Wei W, Hu W
Molecular carcinogenesis 2025 Jan;64(1):57-71
Molecular carcinogenesis 2025 Jan;64(1):57-71
N6-methyladenosine modification of SPOP relieves ferroptosis and diabetic cardiomyopathy by enhancing ubiquitination of VDAC3.
Meng W, Li L
Free radical biology & medicine 2025 Jan;226:216-229
Free radical biology & medicine 2025 Jan;226:216-229
FSTL1 protects against acute aortic dissection by suppressing vascular smooth muscle cell phenotypic switching and degradation of the extracellular matrix.
Li JP, He WB, Xu SW, Liu JZ, Huang ZQ, Li CP, Huang CL, Mai PB, Geng DF, Qiu XF, Liu ZY, Zhang K, Zhou SX
Journal of molecular and cellular cardiology 2025 Jan;198:60-73
Journal of molecular and cellular cardiology 2025 Jan;198:60-73
The double face of licorice-kansui herb pair: Cure or curse, depending on the combining ratio and mediated by hydrogen sulfide.
Li N, Xue W, Wang C, Fan X, Yu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155692
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:155692
Novel applications of metformin in the treatment of septic myocardial injury based on metabolomics and network pharmacology.
Li X, Zhang Z, Li C, Liu J, Fang Q, Zhang M, Huang J
European journal of pharmacology 2025 Jan 5;986:177141
European journal of pharmacology 2025 Jan 5;986:177141
Lactamase β reprograms lipid metabolism to inhibit the progression of endometrial cancer through attenuating MDM2-mediated p53 ubiquitination and degradation.
Zhou T, Li X, Zhao F, Zhou J, Sun B
Archives of biochemistry and biophysics 2025 Feb;764:110287
Archives of biochemistry and biophysics 2025 Feb;764:110287
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Yang S, Sun Y, Wang N, Yang Z, Xing H, Jia J
Molecular and cellular biochemistry 2025 Feb;480(2):1155-1167
Molecular and cellular biochemistry 2025 Feb;480(2):1155-1167
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
Cheng J, Liu O, Bin X, Tang Z
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
GPX3 Overexpression Ameliorates Cardiac Injury Post Myocardial Infarction Through Activating LSD1/Hif1α Axis.
Jiang QQ, Du C, Qian LL, Shan TK, Bao YL, Gu LF, Wang SB, Yang TT, Zhou LH, Wang ZM, He Y, Wang QM, Wang H, Wang RX, Wang LS
Journal of cellular and molecular medicine 2025 Feb;29(3):e70398
Journal of cellular and molecular medicine 2025 Feb;29(3):e70398
Effect of the IL-6 trans-signaling pathway in the absence or presence of TGF-β2 on Schlemm's canal endothelial cells.
Urahashi M, Fujimoto T, Inoue-Mochita M, Inoue T
Experimental eye research 2025 Feb;251:110215
Experimental eye research 2025 Feb;251:110215
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Chen Z, Yun X, Tian J, Li F, Zhang Z, Meng J, Li N, Bian H, Duan S, Zhang L
Advanced healthcare materials 2025 Feb;14(4):e2403227
Advanced healthcare materials 2025 Feb;14(4):e2403227
Exosomal miRNA reprogramming in pyroptotic macrophage drives silica-induced fibroblast-to-myofibroblast transition and pulmonary fibrosis.
Zhang L, Tian J, Li N, Wang Y, Jin Y, Bian H, Xiong M, Zhang Z, Meng J, Han Z, Duan S
Journal of hazardous materials 2025 Feb 5;483:136629
Journal of hazardous materials 2025 Feb 5;483:136629
Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection.
Zhuang X, Zarif M, Shen Y, Zhang Z, He J, Xie L, Wu Q, Lin X, Chen K, Tian Y, Lin Y, Zhang Y, Cai Z, Qiu Z, Chen L
Journal of the American Heart Association 2025 Feb 4;14(3):e037172
Journal of the American Heart Association 2025 Feb 4;14(3):e037172
RPL22L1 fosters malignant features of cervical cancer via the modulation of DUSP6-ERK axis.
Zhang D, Zhao M, Jiang P, Zhou Y, Yan X, Zhou C, Mu Y, Xiao S, Ji G, Wu N, Sun D, Cui X, Ning S, Meng H, Xiao S, Jin Y
Journal of translational medicine 2025 Feb 28;23(1):244
Journal of translational medicine 2025 Feb 28;23(1):244
Decoding the heterogeneous subpopulations of glioblastoma for prognostic stratification and uncovering the promalignant role of PSMC2.
Zhou N, Yan J, Xiong M, Zhu S
Scientific reports 2025 Feb 17;15(1):5714
Scientific reports 2025 Feb 17;15(1):5714
Dihydroartemisinin inhibits EphA2/PI3K/Akt pathway-mediated malignant behaviors and vasculogenic mimicry in glioma stem cells.
Fu H, Wu S, Shen H, Luo K, Huang Z, Lu N, Li Y, Lan Q, Xian Y
Heliyon 2025 Feb 15;11(3):e42095
Heliyon 2025 Feb 15;11(3):e42095
Inhibition Effects and Mechanism Study of rAj-HRP30, a Recombinant Histidine-Rich Peptide from Apostichopus japonicus, on the Viability of Pancreatic Ductal Adenocarcinoma Cells Panc01 and Panc02.
Song Y, Gao S, Jiang J, Zhang Y, Zhang J, Wang X, Lv L, Zhou Z, Wang J
International journal of molecular sciences 2025 Feb 11;26(4)
International journal of molecular sciences 2025 Feb 11;26(4)
Bruton tyrosine kinase promotes wound healing after myocardial infarction by inhibiting the transcription of u-PA.
Dong Z, Zhu JB, Cheng S, Weng XY, Sun XL, Qian JY, Zou YZ, Sun AJ, Wang SJ, Ma LL, Ge JB
Free radical biology & medicine 2025 Feb 1;227:260-275
Free radical biology & medicine 2025 Feb 1;227:260-275
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Liu X, Ding J, Zong Q, Mao Y
Tissue & cell 2025 Dec;97:103066
Tissue & cell 2025 Dec;97:103066
Isobutyric Acid Regulates Gelatinase Secretion by Human Periodontal Ligament Stem Cells Via NF-κB Signalling.
Tu Y, Fu X, Ning X, Zheng H, Zhang L, Guo Q, Huang M, Cao H, Chen H, Jia Y, Duan M, Liu Y, Pi C, Ren B, Liu C, Xie J
International dental journal 2025 Dec;75(6):103966
International dental journal 2025 Dec;75(6):103966
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Jin H, Liu T, Guo Y, Bu W, Liu F, Hou Y
International dental journal 2025 Dec;75(6):103945
International dental journal 2025 Dec;75(6):103945
Bioactive recombinant human elastin gel for reconstructing elastic fibers and rejuvenating endogenously aged skin.
Yang Y, Huang W, Shi J, Tian B, Fu C, Xiao J
Materials today. Bio 2025 Dec;35:102270
Materials today. Bio 2025 Dec;35:102270
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
Qian L, Deng S, Tian T, He Y, Li Y, Wang X, Tian T, Jiang M, Pan Y, Li D
Experimental dermatology 2025 Dec;34(12):e70193
Experimental dermatology 2025 Dec;34(12):e70193
High Shear Stress-Induced Endothelial Piezo1 Downregulation Promotes Intracranial Aneurysm Formation via the PDGF-BB/PDGFRβ Paracrine Signaling Pathway.
Lu Z, Li S, Xu F, Tang H, Zhu S, Wang C, Yang X, Huang Q
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
CNS neuroscience & therapeutics 2025 Dec;31(12):e70715
Different Intensities of Exercise Affect the Prognosis of Ventricular Aneurysm in Mice by Regulating the Progression of Cardiac Fibrosis.
Qi RQ, Song J, Ma HB, Nie ML, Su LH, Dai CL, Zhou FG, Li SJ
Cardiovascular toxicology 2025 Dec;25(12):1891-1902
Cardiovascular toxicology 2025 Dec;25(12):1891-1902
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
Zhu C, Zhang M, Yang W, Gao A, Yu X, Su X, Chen R, Guo M
Epigenetics 2025 Dec;20(1):2512764
Epigenetics 2025 Dec;20(1):2512764
Metabolic signatures for gastric cancer diagnosis and mechanistic insights: a multicenter study.
Zhu J, Huang Y, Li X, Liu B, Yuan L, Wang L, Qian K, Mao Y, Xu Y, Du L, Cheng X
EMBO molecular medicine 2025 Dec;17(12):3355-3376
EMBO molecular medicine 2025 Dec;17(12):3355-3376
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Zhang Y, Tao C, Yin X, Wang Z, Zhang Y, Yu J, Wang Y, Han W
Clinical and translational medicine 2025 Dec;15(12):e70556
Clinical and translational medicine 2025 Dec;15(12):e70556
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
Nie C, Liang H, Zhou J, Liu H, Shang R, Yang H, Jiang W, Qi H, Wang J, Gao A
Cellular signalling 2025 Dec;136:112117
Cellular signalling 2025 Dec;136:112117
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
Zhao J, Ma YB, Xia RH, Jiang ZC, Zhou Y, Wang YN, Yang MY, Dai JJ, Zhu T, Pan LB, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
Wang SH, Jiang JX, Zheng KT, Zhang SJ, Chen TD, Wang Z
Journal of translational medicine 2025 Dec 6;24(1):274
Journal of translational medicine 2025 Dec 6;24(1):274
Identification and functional characterization of genes associated with lipopolysaccharide in lung adenocarcinoma.
Zhou S, Gao M, Dong S, Wang M, Xiao H, Shu Y, Wang X
BMC cancer 2025 Dec 3;26(1):54
BMC cancer 2025 Dec 3;26(1):54
Alkaloids isolated from Scutellaria Barbata D. Don trigger apoptosis and inhibit migration by modulating the p38-p53 pathway in ovarian cancer.
Gao B, Sui X, Choe H, Yang Y, Liu Y, Xia L, Li P, Chen Y, Huo Y, Zhao Z, Ding K, Ma J, Zhao D, Zhang L
Journal of ovarian research 2025 Dec 24;18(1):301
Journal of ovarian research 2025 Dec 24;18(1):301
Decreased scleral Wnt5a(hi) fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.
Zhu H, Chen W, Ling X, Jiao S, Yu L, Liu H, Ding M, Zhang F, Zhou Y, Pan Y, Zhou Z, Qu J, Zhao F, Zhao F, Zhou X
Nature communications 2025 Dec 16;17(1):554
Nature communications 2025 Dec 16;17(1):554
Impaired decidualization and angiogenesis in eutopic endometrium of endometriosis: insights from in vitro models†.
Qin R, Zhong X, Lin J, Li C, Liu X, Qin A, Zheng F
Biology of reproduction 2025 Dec 16;113(6):1539-1548
Biology of reproduction 2025 Dec 16;113(6):1539-1548
Resveratrol Derivatives with a Urea Backbone Exert Anticancer Effects against Liver Cancer via Apoptosis Induction and Metastasis Inhibition.
Hua W, Cheng Y, Li F, Li Y, Lu Z, Li L, Wang D, Liu J
Journal of agricultural and food chemistry 2025 Dec 10;73(49):31429-31443
Journal of agricultural and food chemistry 2025 Dec 10;73(49):31429-31443
Genetic and pharmacological targeting of Snail inhibits atherosclerosis by relieving intraplaque endothelium dysfunction and associated inflammation.
Ren BX, Zeng ZL, Deng L, Hu JM, Chen MZ, Jiang HW, Zang CZ, Fang ST, Weiss SJ, Liu J, Fu R, Wu ZQ
Acta pharmacologica Sinica 2025 Aug;46(8):2196-2212
Acta pharmacologica Sinica 2025 Aug;46(8):2196-2212
Inhibition of VSMC Ferroptosis Mitigates Pathological Vascular Remodeling: A Novel Therapeutic Strategy for Abdominal Aortic Aneurysm.
Zhou Y, Chen Y, Cui Y, Gan N, Xiang Q, Li M, Zeng W, Zheng XL, Dai X, Peng J, Tang Z
Journal of cardiovascular translational research 2025 Aug;18(4):785-799
Journal of cardiovascular translational research 2025 Aug;18(4):785-799
Branched-chain amino acids promote gelatinase secretion from human periodontal ligament stem cells through nuclear factor kappa-B signaling.
Ning X, Zheng H, Tu Y, Guo Q, Ren B, Wu L, Xie J, Liu C
Archives of oral biology 2025 Aug;176:106297
Archives of oral biology 2025 Aug;176:106297
SOX15 Transcriptionally Decreases the Level of MMP2 and Inhibits Vasculogenic Mimicry to Slow Down the Progression of Ovarian Cancer.
Zhao X, Wang X, Wang C, Tian H, Zhou Y, Gong L
Biology of the cell 2025 Aug;117(8):e70031
Biology of the cell 2025 Aug;117(8):e70031
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
Han Y, Fan J, Xia W, Dong X, Ye Y
Biochemical and biophysical research communications 2025 Aug 8;774:152049
Biochemical and biophysical research communications 2025 Aug 8;774:152049
FTO-mediated the destabilization of RASGRF1 mRNA impedes thyroid cancer progression and suppresses macrophage M2 polarization.
Li Z, Ma J, Guan H, Lai J, Xu F, Cao G
Cell biology and toxicology 2025 Aug 4;41(1):123
Cell biology and toxicology 2025 Aug 4;41(1):123
WTAP Dysregulation Mediates HLF-m6A Modification to Inhibit Trophoblast Ferroptosis in Preeclampsia.
Liu S, Zhang L, Li Y, Jia X, Kang J, Sun M, Zhang X, Tang J, Meng T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70961
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70961
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Wang Y, Li Y, Zhang Y, Li Y, Zhao L, Tong L, Zhu X, Wang J, Dong Y
Chemico-biological interactions 2025 Aug 25;417:111562
Chemico-biological interactions 2025 Aug 25;417:111562
Oroxin A suppresses colorectal tumor growth by regulating the TRIM24-mediated ferroptosis and TSPO pathway.
He C, Weng C, Lai Z, Luo H, Chen K, Li T, Li W, Li G
iScience 2025 Aug 15;28(8):113196
iScience 2025 Aug 15;28(8):113196
Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer.
Liu Y, Xue N, Liu Y, Mei J, Cai Y, Wang Z, Lin H, Wan M, Zhou J, Xia T, Zhu Y, Wang S
Translational oncology 2025 Apr;54:102343
Translational oncology 2025 Apr;54:102343
Spatial transcriptomics and single-cell RNA-sequencing revealed dendritic cell-mediated inflammation in keratoconus.
Luo S, Li J, Yang Y, Jiang Y, Jie Y, Ge W
The ocular surface 2025 Apr;36:134-150
The ocular surface 2025 Apr;36:134-150
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Ma YN, Jiang XM, Hu XQ, Wang L, Gao JJ, Liu H, Qi FH, Song PP, Tang W
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Jia H, Li J, Chen X, Liu Z, Wu C, Liu C, Zhang J, Luo M, Huang M, Huang S, Cai M, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
LC-MS/MS assay to confirm that the endogenous metabolite L-Arginine promotes trophoblast invasion in the placenta accreta spectrum through upregulation of the GPRC6A/PI3K/AKT pathway.
Gao Z, Xue M, Wang Z
BMC pregnancy and childbirth 2025 Apr 7;25(1):402
BMC pregnancy and childbirth 2025 Apr 7;25(1):402
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Wang C, Su Y, Shi J, Feng G
Journal of molecular histology 2025 Apr 28;56(3):146
Journal of molecular histology 2025 Apr 28;56(3):146
Impact of Escherichia coli and Lipopolysaccharide on the MAPK Signaling Pathway, MMPs, TIMPs, and the uPA System in Bovine Mammary Epithelial Cells.
Zhang Y, Ding Y, Liang J, Zhang K, Su H, Wang D, Zhang M, Zhao F, Sun Z, Wu Z, Wang F, Cao G, Zhang Y
International journal of molecular sciences 2025 Apr 20;26(8)
International journal of molecular sciences 2025 Apr 20;26(8)
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
Xiao R, Xu P, Li X, Shen F, Tao S, Zhu X, Cai Y, Feng Z, Liu Z, Xiao H, Ding F, Zhu M
Journal of translational medicine 2025 Apr 14;23(1):438
Journal of translational medicine 2025 Apr 14;23(1):438
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
Fan X, Wu L, Cheng T, Lv W, Tian J, Tao J, Tu S, Tan F, Wang Y
Scientific reports 2025 Apr 10;15(1):12225
Scientific reports 2025 Apr 10;15(1):12225
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Chen X, Wang J, Tu F, Yang Q, Wang D, Zhu Q
Ginekologia polska 2024;95(9):661-667
Ginekologia polska 2024;95(9):661-667
Dihydroartemisinin Regulated the MMP-Mediated Cellular Microenvironment to Alleviate Rheumatoid Arthritis.
Guo Q, Wang Q, Chen J, Zhao M, Lu T, Guo Z, Wang C, Wong YK, He X, Chen L, Zhang W, Dai C, Shen S, Pang H, Xia F, Qiu C, Xie D, Wang J
Research (Washington, D.C.) 2024;7:0459
Research (Washington, D.C.) 2024;7:0459
USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.
Wang J, Gan L, Liu F, Yang Q, Deng Q, Jiang D, Zhang C, Zhang L, Wang X
International journal of biological sciences 2024;20(13):5343-5362
International journal of biological sciences 2024;20(13):5343-5362
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Ji Q, Tu Z, Liu J, Zhou Z, Li F, Zhu X, Huang K
International journal of biological sciences 2024;20(11):4364-4381
International journal of biological sciences 2024;20(11):4364-4381
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Ren Y, Yu M, Zheng D, He W, Jin J
Archives of medical science : AMS 2024;20(1):233-247
Archives of medical science : AMS 2024;20(1):233-247
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Wang Y, Deng X, Wei J, Yang Z, Du Y, Song S, Shi Y, Wu H
PloS one 2024;19(6):e0299389
PloS one 2024;19(6):e0299389
Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model.
Xu G, Song X, Wang X, Xue R, Yan X, Qin L, Chang X, Gao J, Chen Z, Song G
International journal of nanomedicine 2024;19:9227-9253
International journal of nanomedicine 2024;19:9227-9253
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Peng C, Kang S, Jiang M, Yang M, Gong X
International journal of nanomedicine 2024;19:8709-8727
International journal of nanomedicine 2024;19:8709-8727
Huangqi-Danshen Decoction Against Renal Fibrosis in UUO Mice via TGF-β1 Induced Downstream Signaling Pathway.
Huang X, Peng Y, Lu L, Gao L, Wu S, Lu J, Liu X
Drug design, development and therapy 2024;18:4119-4134
Drug design, development and therapy 2024;18:4119-4134
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Yang T, Wu P, Jiang L, Chen R, Jin Q, Ye G
Journal of inflammation research 2024;17:8861-8879
Journal of inflammation research 2024;17:8861-8879
Epigenetic silencing of KCTD8 promotes hepatocellular carcinoma growth by activating PI3K/AKT signaling.
Zhou J, Zhang M, Gao A, Herman JG, Guo M
Epigenomics 2024;16(13):929-944
Epigenomics 2024;16(13):929-944
MiR-760 exerts a critical regulatory role in glioma proliferation, migration, and invasion by modulating MMP2 expression.
Qian Z, Xin H, Jia Z, Xia J, Tang Y, Li X, Wu H, Fan Y
Journal of Cancer 2024;15(10):3076-3084
Journal of Cancer 2024;15(10):3076-3084
The cancer-associated fibroblasts interact with malignant T cells in mycosis fungoides and promote the disease progression.
Zhao Y, Li Y, Wang P, Zhu M, Wang J, Xie B, Tang C, Ma Y, Wang S, Jin S, Xu J, Li Z, Zhang X, Li L, Song X, Wang P
Frontiers in immunology 2024;15:1474564
Frontiers in immunology 2024;15:1474564
O304 alleviates abdominal aortic aneurysm formation via AMPK/mTOR/MMP pathway activation.
Sun D, Du Y
Frontiers in pharmacology 2024;15:1457817
Frontiers in pharmacology 2024;15:1457817
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
Liu J, Yang K, Lin X, Xu J, Cui X, Hao J, Wang W, Wang W, Li L, Hao M
Human cell 2024 Sep;37(5):1434-1445
Human cell 2024 Sep;37(5):1434-1445
The potential of brimonidine for myopia treatment: Targeting MMP-2 to regulate choroidal thickness and control eye growth.
Xiang A, Peng Z, He H, Meng X, Luo Y, Yang J, Zeng F, Chen X, Zhong X
Heliyon 2024 Sep 30;10(18):e37416
Heliyon 2024 Sep 30;10(18):e37416
CCDC113 promotes colorectal cancer tumorigenesis and metastasis via TGF-β signaling pathway.
Hou C, Yang Y, Wang P, Xie H, Jin S, Zhao L, Wu G, Xing H, Chen H, Liu B, Du C, Sun X, He L
Cell death & disease 2024 Sep 11;15(9):666
Cell death & disease 2024 Sep 11;15(9):666
Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia.
Zhang Y, Che N, Wang S, Meng J, Zhao N, Han J, Dong X, Li Y, Mo J, Zhao X, Liu T
Journal of gastroenterology 2024 Oct;59(10):941-957
Journal of gastroenterology 2024 Oct;59(10):941-957
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation.
Zhou YY, Zhao SY, Huang FJ, Zhang LJ, Liu YL, Wang J, Ma XJ
Journal of endocrinological investigation 2024 Oct;47(10):2521-2537
Journal of endocrinological investigation 2024 Oct;47(10):2521-2537
Quercetin promotes the proliferation, migration, and invasion of trophoblast cells by regulating the miR-149-3p/AKT1 axis.
Wang D, Zhao XR, Li YF, Wang RL, Li XB, Wang CX, Li YW
The Kaohsiung journal of medical sciences 2024 Oct;40(10):903-915
The Kaohsiung journal of medical sciences 2024 Oct;40(10):903-915
Biomimetic nanocomplex based corneal neovascularization theranostics.
Ye J, Cheng Y, Wen X, Han Y, Wei X, Wu Y, Chen C, Su M, Cai S, Pan J, Liu G, Chu C
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration.
Liu Y, Sun X, Wang L, Dou Y, Tian Y, Yu T, Zhang Y, Zhao Q, Lu J, Feng Y, Wang J, Liu X, Shang Y, Li C, Yang Q
Advanced materials (Deerfield Beach, Fla.) 2024 Oct;36(41):e2408678
Advanced materials (Deerfield Beach, Fla.) 2024 Oct;36(41):e2408678
BRAF V600E mutation mediates invasive and growth features in ameloblastoma.
Zhang CX, Zhang LZ, Lin H, Man QW, Liu B
Oral diseases 2024 Oct;30(7):4426-4439
Oral diseases 2024 Oct;30(7):4426-4439
Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives.
Sun X, Chen J, Huang D, Ding F, Zhao L, Li HM, Wang XS, Zhang YX, Wu CZ
Molecular diversity 2024 Oct;28(5):2749-2758
Molecular diversity 2024 Oct;28(5):2749-2758
Transcription factor ETS1‑mediated ECT2 expression promotes the malignant behavior of prostate cancer cells.
Zheng B, Chen K, Liu X, Wan Z, Wu Y, Xu L, Xiao J, Chen J
Oncology letters 2024 Oct;28(4):453
Oncology letters 2024 Oct;28(4):453
The lncRNA TPTEP1 suppresses PI3K/AKT signalling and inhibits ovarian cancer progression by interacting with PTBP1.
Feng Y, Zhang Z, Yang H, Miao F, Li Y, Zhang M, Cao Y, Li M
Journal of cellular and molecular medicine 2024 Oct;28(20):e70106
Journal of cellular and molecular medicine 2024 Oct;28(20):e70106
CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation.
Pan J, Wu S, Pan Q, Zhang Y, He L, Yao Q, Chen J, Li J, Xu Y
Cell death & disease 2024 Oct 5;15(10):728
Cell death & disease 2024 Oct 5;15(10):728
Targeted Delivery of Celastrol by GA-Modified Liposomal Calcium Carbonate Nanoparticles to Enhance Antitumor Efficacy Against Breast Cancer.
Zhang W, Li J, Yue L, Ji C
Pharmaceutics 2024 Oct 27;16(11)
Pharmaceutics 2024 Oct 27;16(11)
Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics.
Zhang B, Wang W, Song Y, Chen H, Lin X, Chen J, Chen Y, Huang J, Li D, Wu S
Pharmaceuticals (Basel, Switzerland) 2024 Oct 2;17(10)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 2;17(10)
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy.
Qi F, Deng Y, Huang W, Cai Y, Hong K, Xiang S
European journal of histochemistry : EJH 2024 Oct 15;68(4)
European journal of histochemistry : EJH 2024 Oct 15;68(4)
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
Zhang R, Hu M, Liu Y, Li W, Xu Z, He S, Lu Y, Gong Y, Wang X, Hai S, Li S, Qi S, Li Y, Shu Y, Du D, Zhang H, Xu H, Zhou Z, Lei P, Chen HN, Dai L
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation.
Zhao J, Zhang H, Liu Y, Lu G, Wang Z, Mo Q, Wang G, Shen Y, Jiao L
Heliyon 2024 Oct 15;10(19):e37900
Heliyon 2024 Oct 15;10(19):e37900
Yiqihuoxue decoction (GSC) inhibits mitochondrial fission through the AMPK pathway to ameliorate EPCs senescence and optimize vascular aging transplantation regimens.
Liu Y, Niu Z, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Chinese medicine 2024 Oct 14;19(1):143
Chinese medicine 2024 Oct 14;19(1):143
IL-32 regulates trophoblast invasion through miR-205-NFκB-MMP2/9 axis contributing to the pregnancy-induced hypertension†.
Liu J, Li W, Wang J, Bai L, Xu J, Chen X, Wang S, Li L, Xu X
Biology of reproduction 2024 Oct 14;111(4):780-799
Biology of reproduction 2024 Oct 14;111(4):780-799
The role of ALDH1A1 in glioblastoma proliferation and invasion.
Huang YK, Wang TM, Chen CY, Li CY, Wang SC, Irshad K, Pan Y, Chang KC
Chemico-biological interactions 2024 Oct 1;402:111202
Chemico-biological interactions 2024 Oct 1;402:111202
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720
Cell death & disease 2024 Oct 1;15(10):720
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Xie H, Li J, Lu M, Zhang R, Mao H
Molecular biotechnology 2024 Nov;66(11):3182-3194
Molecular biotechnology 2024 Nov;66(11):3182-3194
Fat Mass and Obesity-Associated Protein Regulates Granulosa Cell Aging by Targeting Matrix Metalloproteinase-2 Gene Via an N6-Methyladenosine-YT521-B Homology Domain Family Member 2-Dependent Pathway in Aged Mice.
Li L, Yang L, Shen L, Zhao Y, Wang L, Zhang H
Reproductive sciences (Thousand Oaks, Calif.) 2024 Nov;31(11):3498-3511
Reproductive sciences (Thousand Oaks, Calif.) 2024 Nov;31(11):3498-3511
MiR-424-5p Inhibits Proliferation, Migration, Invasion and Angiogenesis of the HTR-8/SVneo Cells Through Targeting LRP6 Mediated β-catenin.
Fei K, Zhang H, Zhang W, Liao C
Reproductive sciences (Thousand Oaks, Calif.) 2024 Nov;31(11):3428-3439
Reproductive sciences (Thousand Oaks, Calif.) 2024 Nov;31(11):3428-3439
ZnO nanoparticles induce melanoma-like lesions via recruiting dermal dendritic cells in barrier-damaged skin in mice.
You M, Huang Y, Chen Y, Li D, Tang Y, Du YK, Yang H, Liang A, Hu G, Chen Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:114948
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:114948
Sterile Alpha Motif Domain-Containing 5 Suppresses Malignant Phenotypes and Tumor Growth in Breast Cancer: Regulation of Polo-Like Kinase 1 and c-Myc Signaling in a Xenograft Model.
Tuo Y, Ye Y
Cureus 2024 Nov;16(11):e73259
Cureus 2024 Nov;16(11):e73259
POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer.
Yao Q, Gao S, Sun Q, Liuhua Wang, Ren J, Wang D
Discover oncology 2024 Nov 9;15(1):633
Discover oncology 2024 Nov 9;15(1):633
Quercetin Alleviates Scleral Remodeling Through Inhibiting the PERK-EIF2α Axis in Experiment Myopia.
Zhang M, Zhang R, Hao J, Zhao X, Ma Z, Peng Y, Bao B, Xin J, Yin X, Bi H, Guo D
Investigative ophthalmology & visual science 2024 Nov 4;65(13):11
Investigative ophthalmology & visual science 2024 Nov 4;65(13):11
The Inhibitory Effect and Mechanism of the Histidine-Rich Peptide rAj-HRP from Apostichopus japonicus on Human Colon Cancer HCT116 Cells.
Zhang Y, Gao S, Mao J, Song Y, Wang X, Jiang J, Lv L, Zhou Z, Wang J
Molecules (Basel, Switzerland) 2024 Nov 4;29(21)
Molecules (Basel, Switzerland) 2024 Nov 4;29(21)
Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking.
Zheng J, Wang L, Liu A, Shen H, Wang B, Jiang Y, Jing P, Guan D, Yu L, Zhang X
Hereditas 2024 Nov 21;161(1):47
Hereditas 2024 Nov 21;161(1):47
Restoration of ARA metabolic disorders in vascular smooth muscle cells alleviates intimal hyperplasia.
Wu H, Li D, Zhang CY, Huang LL, Zeng YJ, Chen TG, Yu K, Meng JW, Lin YX, Guo R, Zhou Y, Gao G
European journal of pharmacology 2024 Nov 15;983:176824
European journal of pharmacology 2024 Nov 15;983:176824
Circular RNA LDLRAD3 promotes gastric cancer progression by upregulating COL4A5 through sponging miR-h37.
Li C, Xing X, Huang S, Zhu T, Yan B
Journal of the Chinese Medical Association : JCMA 2024 Nov 1;87(11):1018-1028
Journal of the Chinese Medical Association : JCMA 2024 Nov 1;87(11):1018-1028
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
Song X, Wang L, Cai P, Xu Y, Liu Q, Fan D
Toxicology and applied pharmacology 2024 May;486:116938
Toxicology and applied pharmacology 2024 May;486:116938
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520
International journal of biological macromolecules 2024 May;267(Pt 2):131520
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1.
Wang X, Liu D, Hua K, Fang L
Cellular signalling 2024 May;117:111112
Cellular signalling 2024 May;117:111112
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma.
Wu X, Mi T, Jin L, Ren C, Wang J, Zhang Z, Liu J, Wang Z, Guo P, He D
Cancer immunology, immunotherapy : CII 2024 May 7;73(7):122
Cancer immunology, immunotherapy : CII 2024 May 7;73(7):122
Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway.
Wang L, Chen L, Schlenk D, Li F, Liu J
The Science of the total environment 2024 May 20;926:172015
The Science of the total environment 2024 May 20;926:172015
NSUN2 affects diabetic retinopathy progression by regulating MUC1 expression through RNA m(5)C methylation.
Wang R, Xue W, Kan F, Zhang H, Wang D, Wang L, Wang J
Journal of translational medicine 2024 May 19;22(1):476
Journal of translational medicine 2024 May 19;22(1):476
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3'UTR to decrease the expression of CD82.
You G, Li Z, Li L, Xu C
Heliyon 2024 May 15;10(9):e30702
Heliyon 2024 May 15;10(9):e30702
Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Chang R, Su Y, Kong H, Wang F, Xing Y, Jiang L, Xin H
Molecular biotechnology 2024 Mar;66(3):531-543
Molecular biotechnology 2024 Mar;66(3):531-543
Comparative peptidomics analysis of preeclamptic placenta and the identification of a novel bioactive SERPINA1 C-terminal peptide.
Jiang L, Zhu Y, Wu L, Wang C, Yang N, Xu Y, Sun L
Reproductive biology 2024 Mar;24(1):100858
Reproductive biology 2024 Mar;24(1):100858
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Wang H, Liu J, Zhang Z, Peng J, Wang Z, Yang L, Wang X, Hu S, Hong L
Free radical biology & medicine 2024 Mar;214:137-157
Free radical biology & medicine 2024 Mar;214:137-157
LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non-small cell lung cancer.
Yin C, Li J, Li S, Yang X, Lu Y, Wang C, Liu B
Cellular signalling 2024 Mar;115:111031
Cellular signalling 2024 Mar;115:111031
Silica-induced macrophage pyroptosis propels pulmonary fibrosis through coordinated activation of relaxin and osteoclast differentiation signaling to reprogram fibroblasts.
Tian J, Song D, Peng Y, Zhang J, Ma L, Chen Z, Liang L, Zhang Z, Yun X, Zhang L
Ecotoxicology and environmental safety 2024 Mar 15;273:116106
Ecotoxicology and environmental safety 2024 Mar 15;273:116106
Fibulin 1, targeted by microRNA-24-3p, promotes cell proliferation and migration in vascular smooth muscle cells, contributing to the development of atherosclerosis in APOE(-/-) mice.
Ji T, Yan D, Huang Y, Luo M, Zhang Y, Xu T, Gao S, Zhang L, Ruan L, Zhang C
Gene 2024 Mar 10;898:148129
Gene 2024 Mar 10;898:148129
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration.
Yang Y, Song B, Guo M, Gao J, Jiang L, Li Q, Liu Y, Cao J
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
Ecotoxicology and environmental safety 2024 Mar 1;272:116076
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Lin JJ, Chen R, Yang LY, Gong M, Du MY, Mu SQ, Jiang ZA, Li HH, Yang Y, Wang XH, Wang SF, Liu KX, Cao SH, Wang ZY, Zhao AQ, Yang SY, Li C, Sun SG
Journal of advanced research 2024 Jun;60:93-110
Journal of advanced research 2024 Jun;60:93-110
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
Yang C, Xing S, Wei X, Lu J, Zhao G, Ma X, Dai Z, Liang X, Huang W, Liu Y, Jiang X, Zhu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis.
Wang S, Zhang Y, Zhang D, Meng J, Che N, Zhao X, Liu T
Cancer science 2024 Jun;115(6):2067-2081
Cancer science 2024 Jun;115(6):2067-2081
Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs.
Yuan J, Li L, Fan Y, Xu X, Huang X, Shi J, Zhang C, Shi L, Wang Y
European journal of histochemistry : EJH 2024 Jun 27;68(3)
European journal of histochemistry : EJH 2024 Jun 27;68(3)
Cyclin L1 participates in Adriamycin resistance and progression of osteosarcoma via PI3K/AKT-mTOR pathway.
Zhang Y, Zhang T, Chen L, Guo Z, Jiang X
Aging 2024 Jun 26;16(14):11208-11223
Aging 2024 Jun 26;16(14):11208-11223
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
Song N, Cui K, Zeng L, Fan Y, Wang Z, Shi P, Su W, Wang H
Journal of proteomics 2024 Jun 15;301:105182
Journal of proteomics 2024 Jun 15;301:105182
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
Liu Y, Han Y, Liu Y, Huang C, Feng W, Cui H, Li M
Journal of ethnopharmacology 2024 Jun 12;327:117946
Journal of ethnopharmacology 2024 Jun 12;327:117946
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Zhang Y, Chang L, Huang P, Cao M, Hong R, Zhao X, He X, Xu L
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.
Li Y, Zhong X, Yang F
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4823-4831
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4823-4831
Songorine ameliorates LPS-induced sepsis cardiomyopathy by Wnt/β-catenin signaling pathway-mediated mitochondrial biosynthesis.
Chen M, Huang S, Weng S, Weng J, Guo R, Shi B, Liu D
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4713-4725
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4713-4725
Overexpressed FKBP5 mediates colorectal cancer progression and sensitivity to FK506 treatment via the NF-κB signaling pathway.
Liu T, Wang C, Xia Z
The FEBS journal 2024 Jul;291(14):3128-3146
The FEBS journal 2024 Jul;291(14):3128-3146
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Li H, Qin S, Tang J, Wang T, Ren W, Di L, Bo W, Ma Y, Wu F, Xu Z, Song W, Cai M, Xi Y, Tian Z
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
Zhang H, Han B, Tian S, Gong Y, Chen L, Liu L
Aging 2024 Jul 9;16(13):11103-11116
Aging 2024 Jul 9;16(13):11103-11116
CCZ1 Accelerates the Progression of Cervical Squamous Cell Carcinoma by Promoting MMP2/MMP17 Expression.
Yu J, Yuan Z, Liu J, Deng L, Zhao Y, Wang S, Tang E, Yang X, Li N, An J, Wu L
Biomedicines 2024 Jul 3;12(7)
Biomedicines 2024 Jul 3;12(7)
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Wu J, Song Y, Wang J, Wang T, Yang L, Shi Y, Song B, Yu Z
Heliyon 2024 Jul 15;10(13):e33802
Heliyon 2024 Jul 15;10(13):e33802
Loss of monopolar spindle-binding protein 3B expression promotes colorectal cancer invasiveness by activation of target of rapamycin kinase/autophagy signaling.
Sun J, Zhang JX, Li MS, Qin MB, Cheng RX, Wu QR, Chen QL, Yang D, Liao C, Liu SQ, Huang JA
World journal of gastroenterology 2024 Jul 14;30(26):3229-3246
World journal of gastroenterology 2024 Jul 14;30(26):3229-3246
P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma.
Chi Z, Wang Q, Wang X, Li D, Tong L, Shi Y, Yang F, Guo Q, Zheng J, Chen Z
Scientific reports 2024 Jul 1;14(1):15023
Scientific reports 2024 Jul 1;14(1):15023
Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis.
Meng X, Chen Z, Li T, Nie Z, Han H, Zhong S, Yin Z, Sun S, Xie J, Shen J, Xu X, Gao C, Ran L, Xu B, Xiang Z, Wang J, Sun P, Xin P, A X, Zhang C, Qiu G, Gao H, Bian Y, Xu M, Cao B, Li F, Zheng L, Zhang X, Xiao L
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jan;76(1):32-47
Arthritis & rheumatology (Hoboken, N.J.) 2024 Jan;76(1):32-47
Vasculogenic mimicry-associated novel gene signature predicted prognosis and response to immunotherapy in lung adenocarcinoma.
Zhang L, Wu J, Yin WW, Hu J, Liao L, Ma J, Xu Z, Wu S
Pathology, research and practice 2024 Jan;253:155048
Pathology, research and practice 2024 Jan;253:155048
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner.
Wang T, Wagner RT, Hlady RA, Pan X, Zhao X, Kim S, Wang L, Lee JH, Luo H, Castle EP, Lake DF, Ho TH, Robertson KD
Molecular oncology 2024 Jan;18(1):44-61
Molecular oncology 2024 Jan;18(1):44-61
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Xu L, Zhang L, Zhang S, Yang J, Zhu A, Sun J, Kalvakolanu DV, Cong X, Zhang J, Tang J, Guo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
A drug-free cardiovascular stent functionalized with tailored collagen supports in-situ healing of vascular tissues.
Wu H, Yang L, Luo R, Li L, Zheng T, Huang K, Qin Y, Yang X, Zhang X, Wang Y
Nature communications 2024 Jan 25;15(1):735
Nature communications 2024 Jan 25;15(1):735
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
Wu J, Wang W, Yuan F, Zheng J, Zhang W, Guo H, Wang L, Dai C, Han F, Wu X, Gao J
International immunopharmacology 2024 Jan 25;127:111375
International immunopharmacology 2024 Jan 25;127:111375
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Xue Z, Zhang Y, Zhao R, Liu X, Grützmann K, Klink B, Zhang X, Wang S, Zhao W, Sun Y, Han M, Wang X, Hu Y, Liu X, Yang N, Qiu C, Li W, Huang B, Li X, Bjerkvig R, Wang J, Zhou W
Journal of experimental & clinical cancer research : CR 2024 Jan 22;43(1):25
Journal of experimental & clinical cancer research : CR 2024 Jan 22;43(1):25
miR-146a regulates emphysema formation and abnormal inflammation in the lungs of two mouse models.
Yoshikawa H, Sato T, Horikoshi K, Komura M, Nitta NA, Mitsui A, Koike K, Kodama Y, Takahashi K
American journal of physiology. Lung cellular and molecular physiology 2024 Jan 1;326(1):L98-L110
American journal of physiology. Lung cellular and molecular physiology 2024 Jan 1;326(1):L98-L110
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
Wang Y, Mang X, Li D, Wang Z, Chen Y, Cai Z, Tan F
Redox biology 2024 Feb;69:102991
Redox biology 2024 Feb;69:102991
RETRACTED ARTICLE: MiR-28-5p Promotes Osteosarcoma Development by Suppressing URGCP Expression.
Zhang C, Wu Y, Yue Q, Zhang X, Hao Y, Liu J
Biochemical genetics 2024 Feb;62(1):574
Biochemical genetics 2024 Feb;62(1):574
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
Chi Z, Wang Q, Tong L, Qiu J, Yang F, Guo Q, Li W, Zheng J, Chen Z
Cell biology international 2024 Feb;48(2):174-189
Cell biology international 2024 Feb;48(2):174-189
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
Glucagon Enhances Chemotherapy Efficacy By Inhibition of Tumor Vessels in Colorectal Cancer.
Xu Y, Ni F, Sun D, Peng Y, Zhao Y, Wu X, Li S, Qi X, He X, Li M, Zhou Y, Zhang C, Yan M, Yao C, Zhu S, Yang Y, An B, Yang C, Zhang G, Jiang W, Mi J, Chen X, Wei P, Tian G, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2307271
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2307271
Ginseng-Sanqi-Chuanxiong (GSC) extracts attenuate d-galactose-induced vascular aging in mice via inhibition of endothelial progenitor cells senescence.
Liu Y, Liu Y, Wang X, Xiu C, Hu Y, Wang J, Lei Y, Yang J
Heliyon 2024 Feb 29;10(4):e25253
Heliyon 2024 Feb 29;10(4):e25253
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Zhou H, Li J, He Y, Xia X, Liu J, Xiong H
Cancer cell international 2024 Feb 24;24(1):85
Cancer cell international 2024 Feb 24;24(1):85
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
Wang H, Xu YH, Guo Y
Journal of ovarian research 2024 Feb 23;17(1):50
Journal of ovarian research 2024 Feb 23;17(1):50
Shenlian extract improves atherosclerosis by relieving adventitial inflammation.
Han S, Nie C, Wang C, Song M, Li J, Cui X, Yang Q, Li Y, Chen Y, Li Q, Cai W, Weng X, Wang Y, Zhu X
Journal of ethnopharmacology 2024 Feb 10;320:117339
Journal of ethnopharmacology 2024 Feb 10;320:117339
Fluvastatin prevents lung metastasis in triple-negative breast cancer by triggering autophagy via the RhoB/PI3K/mTOR pathway.
Xu WH, Zhang T, Zhou Y, Mao Y
Experimental cell research 2024 Feb 1;435(1):113893
Experimental cell research 2024 Feb 1;435(1):113893
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Xu F, Zhao X, Zhang J, Shen C
Journal of molecular histology 2024 Dec;55(6):1295-1306
Journal of molecular histology 2024 Dec;55(6):1295-1306
Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation.
Du Y, Liu T, Ding T, Zeng X, Chen Q, Zhao H
Materials today. Bio 2024 Dec;29:101305
Materials today. Bio 2024 Dec;29:101305
Biogenesis of circRBM33 mediated by N6-methyladenosine and its function in abdominal aortic aneurysm.
Xu Y, Weng X, Qiu J, Wang S
Epigenetics 2024 Dec;19(1):2392401
Epigenetics 2024 Dec;19(1):2392401
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
Wang H, Fan N, Cui X, Xie R, Tang Y, Thomas AM, Li S, Zhang JV, Liu S, Qin H
Placenta 2024 Dec;158:240-252
Placenta 2024 Dec;158:240-252
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
Sun Q, Xu J, Yuan F, Liu Y, Chen Q, Guo L, Dong H, Liu B
Cancer biology & therapy 2024 Dec 31;25(1):2321770
Cancer biology & therapy 2024 Dec 31;25(1):2321770
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
Du Q, Zhang M, Gao A, He T, Guo M
Cancer biology & therapy 2024 Dec 31;25(1):2302924
Cancer biology & therapy 2024 Dec 31;25(1):2302924
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Yao W, Shang L, Wang Y, Xu L, Bai Y, Feng M, Jia X, Wu S
Journal of translational medicine 2024 Dec 31;22(1):1167
Journal of translational medicine 2024 Dec 31;22(1):1167
Activated PRDM1-CREBBP contributes to preeclampsia by regulating apoptosis and invasion of the human trophoblast cells.
Zhang X, Sun L
iScience 2024 Dec 20;27(12):111484
iScience 2024 Dec 20;27(12):111484
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
Gao M, Wang M, Zhou S, Hou J, He W, Shu Y, Wang X
Cancer cell international 2024 Dec 18;24(1):400
Cancer cell international 2024 Dec 18;24(1):400
FUT3 promotes gastric cancer cell migration by synthesizing Lea on ITGA6 and GLG1, affecting adhesion and vesicle distribution.
Wu F, Cao L, Zhang J, Cai S, Wu H, Miao J, Zhao L, Zhao C, Wang X, Ramzan MA, Ali S, Wu F, Ni L, Liu L, Qin Y, Huang C
Life sciences 2024 Dec 15;359:123193
Life sciences 2024 Dec 15;359:123193
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
Jiang D, Qi Z, Xu ZY, Li YR
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563
Oncogene 2024 Aug;43(34):2548-2563
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Lu P, Fan J, Li B, Wang X, Song M
Atherosclerosis 2024 Aug;395:117575
Atherosclerosis 2024 Aug;395:117575
Development and Comparative Study of a Mouse Model of Airway Inflammation and Remodeling Induced by Exosomes Derived from Bone Marrow Mesenchymal Stem Cells.
Yao B, Liu J, Xie J, Li Z, Luo Y, Wang M
Bulletin of experimental biology and medicine 2024 Aug;177(4):544-551
Bulletin of experimental biology and medicine 2024 Aug;177(4):544-551
Melatonin enhances the efficacy of anti-PD-L1 by improving hypoxia in residual tumors after insufficient radiofrequency ablation.
Ren Y, Zhu L, Guo Y, Ma J, Yang L, Zheng C, Dong X
Journal of pharmaceutical analysis 2024 Aug;14(8):100942
Journal of pharmaceutical analysis 2024 Aug;14(8):100942
Fc receptor-like A promotes malignant behavior in renal cell carcinoma and correlates with tumor immune infiltration.
Liu JP, Jiang YF, Liu JW, Tian CJ, Lin YZ, Yang YZ, Zhang ZK, Fang YL, Huang B, Lin H
Cancer medicine 2024 Aug;13(15):e70072
Cancer medicine 2024 Aug;13(15):e70072
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
Duan Y, Chen Y, He Y, Gong R, Xia Z
Scientific reports 2024 Aug 7;14(1):18353
Scientific reports 2024 Aug 7;14(1):18353
Activation of P2X7 Receptor Mediates the Abnormal Ovulation Induced by Chronic Restraint Stress and Chronic Cold Stress.
Fan X, Wang J, Ma Y, Chai D, Han S, Xiao C, Huang Y, Wang X, Wang J, Wang S, Xiao L, Zhang C
Biology 2024 Aug 15;13(8)
Biology 2024 Aug 15;13(8)
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
Liu XR, Li SF, Mei WY, Liu XD, Zhou RB
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection.
Xue S, Leng S, Zhang F, Dang Z, Su G, Yu W
Experimental and therapeutic medicine 2024 Apr;27(4):145
Experimental and therapeutic medicine 2024 Apr;27(4):145
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Lin M, Xiao Y, Dai Y, Mao Y, Xu L, Zhang Q, Chen Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Histone deacetylase 9-mediated phenotypic transformation of vascular smooth muscle cells is a potential target for treating aortic aneurysm/dissection.
Dang Z, Li H, Xue S, Shao B, Ning Y, Su G, Zhang F, Yu W, Leng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116396
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116396
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Zhang T, Cao RJ, Niu JL, Chen ZH, Mu SQ, Cao T, Pang JX, Dong LH
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Wei X, Li Y, Jiang T, Luo P, Dai Y, Wang Q, Xu M, Yan J, Li Y, Gao J, Liu L, Zhang C, Liu Y
European journal of pharmacology 2024 Apr 5;968:176397
European journal of pharmacology 2024 Apr 5;968:176397
Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.
Fan Y, Zhang W, Huang X, Fan M, Shi C, Zhao L, Pi G, Zhang H, Ni S
Nature communications 2024 Apr 5;15(1):2939
Nature communications 2024 Apr 5;15(1):2939
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
Chen D, Cai B, Zhu Y, Ma Y, Yu X, Xiong J, Shen J, Tie W, Zhang Y, Guo F
Clinical epigenetics 2024 Apr 4;16(1):51
Clinical epigenetics 2024 Apr 4;16(1):51
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
Yang L, Ruan Y, Xu H
BMC cancer 2024 Apr 29;24(1):544
BMC cancer 2024 Apr 29;24(1):544
BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling.
Huang X, Guo J, Ning A, Zhang N, Sun Y
Cardiovascular diabetology 2024 Apr 25;23(1):140
Cardiovascular diabetology 2024 Apr 25;23(1):140
Establishment of a novel microfluidic co-culture system for simultaneous analysis of multiple indicators of gefitinib sensitivity in colorectal cancer cells.
Li X, Li W, Wang J, Wang Q, Liang M, Chen S, Ba W, Fang J
Mikrochimica acta 2024 Apr 22;191(5):279
Mikrochimica acta 2024 Apr 22;191(5):279
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
Wu M, Huang X, Wu B, Zhu M, Zhu Y, Yu L, Lan T, Liu J
Molecular biology reports 2024 Apr 20;51(1):553
Molecular biology reports 2024 Apr 20;51(1):553
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
Liu BX, Xie Y, Zhang J, Zeng S, Li J, Tao Q, Yang J, Chen Y, Zeng C
International immunopharmacology 2024 Apr 20;131:111759
International immunopharmacology 2024 Apr 20;131:111759
MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells.
Liu W, Ren Y, Wang T, Wang M, Xu Y, Zhang J, Bi J, Wu Z, Lv Y, Wu R
European journal of pharmacology 2024 Apr 15;969:176462
European journal of pharmacology 2024 Apr 15;969:176462
Integrating bulk and single-cell sequencing data to construct a Scissor(+) dendritic cells prognostic model for predicting prognosis and immune responses in ESCC.
Cheng M, Xiong J, Liu Q, Zhang C, Li K, Wang X, Chen S
Cancer immunology, immunotherapy : CII 2024 Apr 15;73(6):97
Cancer immunology, immunotherapy : CII 2024 Apr 15;73(6):97
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
He NN, Wang JA, Huang D, Sun XL, Ding F, Zhao L, Zhang YX, Li HM, Wu CZ
Chemical & pharmaceutical bulletin 2023;71(11):798-803
Chemical & pharmaceutical bulletin 2023;71(11):798-803
HMGB1 released from dead tumor cells after insufficient radiofrequency ablation promotes progression of HCC residual tumor via ERK1/2 pathway.
Zhou Y, Liu X, Zhang W, Xu Y, Zhang Q, Xiong S, Tang H, Luo B
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2174709
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023;40(1):2174709
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
Zhu L, Yao Z, Luo Q, Liu Y, Zhao W, Shao C, Shao S, Cui F
International journal of medical sciences 2023;20(8):1038-1045
International journal of medical sciences 2023;20(8):1038-1045
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
Que Z, Luo B, Yu P, Qi D, Shangguan W, Wang P, Liu J, Li Y, Li H, Ke R, Wu E, Tian J
International journal of biological sciences 2023;19(16):5204-5217
International journal of biological sciences 2023;19(16):5204-5217
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
Zhu M, Sun Y, Xue H, Wu G, Wang Z, Shi J, Ma J, Gu B, Yan X
International journal of general medicine 2023;16:2831-2848
International journal of general medicine 2023;16:2831-2848
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
Inhibition of Non-small Cell Lung Cancer by Ferroptosis and Apoptosis Induction through P53 and GSK-3β/Nrf2 Signal Pathways using Qingrehuoxue Formula.
Xu F, Zhang J, Ji L, Cui W, Cui J, Tang Z, Sun N, Zhang G, Guo M, Liu B, Dong J
Journal of Cancer 2023;14(3):336-349
Journal of Cancer 2023;14(3):336-349
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
Li F, Wang L, Wang Y, Shen H, Kou Q, Shen C, Xu X, Zhang Y, Zhang J
Journal of Cancer 2023;14(15):2820-2832
Journal of Cancer 2023;14(15):2820-2832
Pan-cancer analysis shows that IBSP is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including osteosarcoma.
Pan B, Cheng X, Tan W, Liu R, Wu X, He J, Fan Q, Zhang Y, Cheng J, Deng Y
Frontiers in immunology 2023;14:1188256
Frontiers in immunology 2023;14:1188256
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
Shi S, Zhong J, Peng W, Yin H, Zhong D, Cui H, Sun X
Frontiers in oncology 2023;13:1075716
Frontiers in oncology 2023;13:1075716
The Role of miR-1183: A Potential Suppressor in Hepatocellular Carcinoma via Regulating Splicing Factor SRSF1.
Yao Z, Liu N, Lin H, Zhou Y
Journal of hepatocellular carcinoma 2023;10:1169-1180
Journal of hepatocellular carcinoma 2023;10:1169-1180
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Zhang Y, Zhao X, Guo C, Zhang Y, Zeng F, Yin Q, Li Z, Shao L, Zhou D, Liu L
Neuroscience bulletin 2023 Sep;39(9):1375-1395
Neuroscience bulletin 2023 Sep;39(9):1375-1395
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Li L, Wang H, Pang S, Wang L, Fan Z, Ma C, Yang S, Banda J, Hui Q, Lv F, Fan H, Huang T, Zhang X, Wang X
The Journal of biological chemistry 2023 Sep;299(9):105127
The Journal of biological chemistry 2023 Sep;299(9):105127
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Qu Y, Qiu L, Qiu H, Shen Y, Tang M, Huang Y, Peng Y, Wang J, Fu Q
Cytokine 2023 Sep;169:156309
Cytokine 2023 Sep;169:156309
Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathway.
Zhang J, Zhuang Z, Guo M, Wu K, Yang Q, Min X, Cui W, Xu F
Journal of traditional and complementary medicine 2023 Sep;13(5):417-429
Journal of traditional and complementary medicine 2023 Sep;13(5):417-429
Gut Microbiota Metabolite 3-Indolepropionic Acid Directly Activates Hepatic Stellate Cells by ROS/JNK/p38 Signaling Pathways.
Yuan X, Yang J, Huang Y, Li J, Li Y
Biomolecules 2023 Sep 28;13(10)
Biomolecules 2023 Sep 28;13(10)
Bisphenol P and bisphenol M promote triple-negative breast cancer metastasis through activation of AKT pathways.
Liu J, Wang H, Hou X, Fan L, Yang F, Dai Y, Deng Y, Fu Z, Shu X, Sun B, Liu Y
The Science of the total environment 2023 Sep 20;892:164748
The Science of the total environment 2023 Sep 20;892:164748
[Aumolertinib inhibits proliferation, invasion and migration and promotes apoptosis of neuroblastoma cells by downregulating MMP2 and MMP9 expression].
Liu X, Yang Y, Cai H, Zhang Y, Fan F, Li X, Li S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1493-1499
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1493-1499
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Dong Y, Tan H, Wang L, Liu Z
Cancer cell international 2023 Sep 2;23(1):191
Cancer cell international 2023 Sep 2;23(1):191
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Haoran S, Zhishan J, Yan M, Ruilin M, Jianjian C, Zejun Y, Jianwen Z, Hui G, Yin Z
Stem cells (Dayton, Ohio) 2023 Sep 15;41(9):877-891
Stem cells (Dayton, Ohio) 2023 Sep 15;41(9):877-891
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
Formin-related protein 1 facilitates proliferation and aggressive phenotype of clear cell renal cell carcinoma through MAPK/MMP2 pathway.
Ma G, Zhang B, Fu S, Lu J, Zhang L, Shang P, Yue Z
Molecular and cellular probes 2023 Oct;71:101921
Molecular and cellular probes 2023 Oct;71:101921
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Wenjuan T, Yu HU, Man Z, Mingzhi D, Tieming L, Ammar S, Yingzhuan Z, Yanmin Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Single-cell RNA sequencing of retina revealed novel transcriptional landscape in high myopia and underlying cell-type-specific mechanisms.
Yao Y, Chen Z, Wu Q, Lu Y, Zhou X, Zhu X
MedComm 2023 Oct;4(5):e372
MedComm 2023 Oct;4(5):e372
HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.
Tong Z, Shen Y, Yuan Q, Yu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119553
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119553
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Li W, Xu L, Cao J, Ge J, Liu X, Liu P, Teng Y, Wang S, Sun Y, Liu M, Tian L
Immunology 2023 Oct;170(2):253-269
Immunology 2023 Oct;170(2):253-269
Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
Lin W, Song Y, Li T, Yan J, Zhang R, Han L, Ba X, Huang Y, Qin K, Chen Z, Wang Y, Tu S, Huang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115394
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115394
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Yang Z, Wu G, Zhao J, Shi G, Zhou J, Zhou X
Cancer medicine 2023 Oct;12(19):19850-19865
Cancer medicine 2023 Oct;12(19):19850-19865
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.
Ye J, Liu W, Yu X, Wu L, Chen Z, Yu Y, Wang J, Bai S, Zhang M
Cell death discovery 2023 Oct 16;9(1):378
Cell death discovery 2023 Oct 16;9(1):378
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Wang L, Wang X, Sun H, Wang W, Cao L
Aging 2023 Oct 12;15(19):10746-10766
Aging 2023 Oct 12;15(19):10746-10766
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM, Fu H
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia‑induced invasion and therapeutic resistance.
Lumibao JC, Haak PL, Kolossov VL, Chen JE, Stutchman J, Ruiz A, Sivaguru M, Sarkaria JN, Harley BAC, Steelman AJ, Gaskins HR
International journal of oncology 2023 Nov;63(5)
International journal of oncology 2023 Nov;63(5)
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Hong JW, Yu Y, Wang LS, Li Z, Zhang R, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Hydrogen sulfide inhibits the rupture of fetal membranes throngh anti-aging pathways.
Wang J, Xu J, Chao B, Liu H, Xie L, Qi H, Luo X
Placenta 2023 Nov;143:22-33
Placenta 2023 Nov;143:22-33
Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth.
Mi T, Tan X, Wang Z, Zhang Z, Jin L, Wang J, Li M, Wu X, He D
European journal of medical research 2023 Nov 8;28(1):503
European journal of medical research 2023 Nov 8;28(1):503
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Wang H, Yang L, Liu R, He H, Zhang M, Xu Y
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Wang Y, Mang X, Li D, Chen Y, Cai Z, Tan F
Free radical biology & medicine 2023 Nov 1;208:134-152
Free radical biology & medicine 2023 Nov 1;208:134-152
NONHSAG028908.3 sponges miR‑34a‑5p to promote growth of colorectal cancer via targeting ALDOA.
Wang C, Xin H, Yan G, Liu Z
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma.
Zhang C, Wang R, Li M, Yang Q
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Wang T, Huang X, Liu J, Liu W, Yang Z, He K, Chen J, Zhao L
Environmental toxicology 2023 May;38(5):1143-1152
Environmental toxicology 2023 May;38(5):1143-1152
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Wu Y, Wang Z, Li S, Chen X, Zhou S
Experimental and therapeutic medicine 2023 May;25(5):195
Experimental and therapeutic medicine 2023 May;25(5):195
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Chou SH, Lin HC, Chen SW, Tai YT, Jung SM, Ko FH, Pang JS, Chu PH
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Chrysin protects against cerebral ischemia-reperfusion injury in hippocampus via restraining oxidative stress and transition elements.
Shang J, Jiao J, Yan M, Wang J, Li Q, Shabuerjiang L, Lu Y, Song Q, Bi L, Huang G, Zhang X, Wen Y, Cui Y, Wu K, Li G, Wang P, Liu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114534
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114534
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
Chen H, Cai X, Du B, Cai J, Luo Z
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
Accessing Apoptosis Induction and Metastasis Inhibition Effect of Magnolol on Triple Negative Breast Cancer In Vitro.
Li YC, Wong CN, Hsu FT, Chen JH, Yang CC, Liu HH, Chen WL, Weng YS
In vivo (Athens, Greece) 2023 May-Jun;37(3):1028-1036
In vivo (Athens, Greece) 2023 May-Jun;37(3):1028-1036
RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer.
Li F, Sun H, Yu Y, Che N, Han J, Cheng R, Zhao N, Guo Y, Huang C, Zhang D
Cell death & disease 2023 May 22;14(5):335
Cell death & disease 2023 May 22;14(5):335
Peptidase Inhibitor 16 Attenuates Left Ventricular Injury and Remodeling After Myocardial Infarction by Inhibiting the HDAC1-Wnt3a-β-Catenin Signaling Axis.
Wang L, Du A, Lu Y, Zhao Y, Qiu M, Su Z, Shu H, Shen H, Sun W, Kong X
Journal of the American Heart Association 2023 May 16;12(10):e028866
Journal of the American Heart Association 2023 May 16;12(10):e028866
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
Hu M, Li H, Li G, Wang Y, Liu J, Zhang M, Shen D, Wang X
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation.
Li Z, Jiang D, Liu F, Li Y
In vitro cellular & developmental biology. Animal 2023 Mar;59(3):193-203
In vitro cellular & developmental biology. Animal 2023 Mar;59(3):193-203
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
Xie Y, Zhang Y, Liu X, Cao L, Han M, Wang C, Chen J, Zhang X
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.
Han S, Jin X, Hu T, Chi F
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Yang J, Hasenbilige, Bao S, Luo S, Jiang L, Li Q, Kong Y, Cao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113609
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx.
Crompton M, Ferguson JK, Ramnath RD, Onions KL, Ogier AS, Gamez M, Down CJ, Skinner L, Wong KH, Dixon LK, Sutak J, Harper SJ, Pontrelli P, Gesualdo L, Heerspink HL, Toto RD, Welsh GI, Foster RR, Satchell SC, Butler MJ
JCI insight 2023 Mar 8;8(5)
JCI insight 2023 Mar 8;8(5)
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Chen Y, Yang P, Wang J, Gao S, Xiao S, Zhang W, Zhu M, Wang Y, Ke X, Jing H
Experimental hematology & oncology 2023 Mar 7;12(1):28
Experimental hematology & oncology 2023 Mar 7;12(1):28
[DTX2 overexpression promotes migration and invasion of colorectal cancer cells through the Notch2/Akt axis].
Ma Z, Zhao X, Zhang X, Xu G, Liu F
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):340-348
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):340-348
Rab32 promotes glioblastoma migration and invasion via regulation of ERK/Drp1-mediated mitochondrial fission.
Chen P, Lu Y, He B, Xie T, Yan C, Liu T, Wu S, Yeh Y, Li Z, Huang W, Zhang X
Cell death & disease 2023 Mar 15;14(3):198
Cell death & disease 2023 Mar 15;14(3):198
Integrated miRNA and mRNA omics reveal dioscin suppresses migration and invasion via MEK/ERK and JNK signaling pathways in human endometrial carcinoma in vivo and in vitro.
Li XL, Zhang XX, Ma RH, Ni ZJ, Thakur K, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Journal of ethnopharmacology 2023 Mar 1;303:116027
Journal of ethnopharmacology 2023 Mar 1;303:116027
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Dong M, Luo Y, Lan Y, He Q, Xu L, Pei Z
Heliyon 2023 Jun;9(6):e17613
Heliyon 2023 Jun;9(6):e17613
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Gao L, Tong S, Liu J, Cai J, Ye Z, Zhou L, Song P, Li Z, Lei P, Wei H, Hua Q, Tian D, Cai Q
Heliyon 2023 Jun;9(6):e16559
Heliyon 2023 Jun;9(6):e16559
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Xu Q, Yu ZX, Xie YL, Bai L, Liang SR, Ji QH, Zhou J
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Li Y, Wang D, Zhang Z, Wang Y, Zhang Z, Liang Z, Liu F, Chen L
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
Photodiagnosis and photodynamic therapy 2023 Jun;42:103342
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
Zeng C, Wu JK, Lu X
International journal of experimental pathology 2023 Jun;104(3):140-150
International journal of experimental pathology 2023 Jun;104(3):140-150
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Wu B, Shi L, Wu Y
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
m(6)A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma.
Zhu X, Wu X, Yang H, Xu Q, Zhang M, Liu X, Lv K
Biology direct 2023 Jun 3;18(1):27
Biology direct 2023 Jun 3;18(1):27
Morusin shows potent antitumor activity for melanoma through apoptosis induction and proliferation inhibition.
Liu W, Ji Y, Wang F, Li C, Shi S, Liu R, Li Q, Guo L, Liu Y, Cui H
BMC cancer 2023 Jun 29;23(1):602
BMC cancer 2023 Jun 29;23(1):602
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Chen WJ, Zhuang Y, Peng W, Cui W, Zhang SJ, Wang JW
Chinese medicine 2023 Jun 29;18(1):80
Chinese medicine 2023 Jun 29;18(1):80
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
Zhao Y, Hu F, Wang Q
Heliyon 2023 Jul;9(7):e18289
Heliyon 2023 Jul;9(7):e18289
TEAD4 predicts poor prognosis and transcriptionally targets PLAGL2 in serous ovarian cancer.
Tong X, Liu YS, Tong R, Tang WW, Li XM, Wang CY, Wang YP
Human cell 2023 Jul;36(4):1535-1547
Human cell 2023 Jul;36(4):1535-1547
EIF4A3-Induced Upregulation of hsa_circ_0040039 is a Biomarker and Aggravates IL-1β-Stimulated Intervertebral Disc Degeneration.
Li L, Cao Y, Deng H, Jia J, Fan X
Applied biochemistry and biotechnology 2023 Jul;195(7):4292-4307
Applied biochemistry and biotechnology 2023 Jul;195(7):4292-4307
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
Wu J, Zhang L, Li W, Wang L, Jia Q, Shi F, Li K, Liao L, Shi Y, Wu S
Scientific reports 2023 Jul 5;13(1):10906
Scientific reports 2023 Jul 5;13(1):10906
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
Zhao B, Wan Y, Zhou X, Zhang J, Chen J, Yang J, Liu Y, Chen W, Zhong Y, Qian H
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway.
Cao Q, Ma J, Li W, Hong P, Shen T, Tong M
Genes & genomics 2023 Jan;45(1):1-11
Genes & genomics 2023 Jan;45(1):1-11
Aiphanol, a multi-targeting stilbenolignan, potently suppresses mouse lymphangiogenesis and lymphatic metastasis.
Chen SM, Zhao CK, Yao LC, Wang LX, Ma YN, Meng L, Cai SQ, Liu CY, Qu LK, Jia YX, Shou CC
Acta pharmacologica Sinica 2023 Jan;44(1):189-200
Acta pharmacologica Sinica 2023 Jan;44(1):189-200
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Small GTP-binding protein Rap1 mediates EGF and HB-EGF signaling and modulates EGF receptor expression in HTR-8/SVneo extravillous trophoblast cells.
Yoshie M, Ohishi K, Ishikawa G, Tsuru A, Kusama K, Azumi M, Tamura K
Reproductive medicine and biology 2023 Jan-Dec;22(1):e12537
Reproductive medicine and biology 2023 Jan-Dec;22(1):e12537
B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.
Fan J, Wang Y, Liang X, Peng Y, Li S, Li X, Zhou F, Li Y
Medical oncology (Northwood, London, England) 2023 Jan 24;40(3):85
Medical oncology (Northwood, London, England) 2023 Jan 24;40(3):85
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Xia Y, Hao L, Li Y, Li Y, Chen J, Li L, Han X, Liu Y, Wang X, Li D
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
METTL3 and METTL14-mediated N(6)-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis.
Shen L, Zhang C, Zhang Y, Yang Y
Reproductive biomedicine online 2023 Feb;46(2):255-265
Reproductive biomedicine online 2023 Feb;46(2):255-265
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Zhang S, Yang L, Hong S, Liu J, Cheng J, He Y, Hong L
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Wang DN, Ni JJ, Li JH, Gao YQ, Ni FJ, Zhang ZZ, Fang JY, Lu J, Yao YF
PLoS pathogens 2023 Feb;19(2):e1011189
PLoS pathogens 2023 Feb;19(2):e1011189
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Liu XM, Li Z, Xie XR, Wang JQ, Qiao X, Qiao X, Xie CZ, Xu JY
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
Tang S, Ma J, Su P, Lei H, Tong Y, Cai L, Xu S, Mao X, Sun P
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
Nanomechanical-based classification of prostate tumor using atomic force microscopy.
Zeng J, Zhang Y, Xu R, Chen H, Tang X, Zhang S, Yang H
The Prostate 2023 Dec;83(16):1591-1601
The Prostate 2023 Dec;83(16):1591-1601
SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection.
Li J, Yu C, Yu K, Chen Z, Xing D, Zha B, Xie W, Ouyang H
Experimental and therapeutic medicine 2023 Dec;26(6):546
Experimental and therapeutic medicine 2023 Dec;26(6):546
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression.
Wang X, Gao F, Cheng C, Zhang Y
Functional & integrative genomics 2023 Dec 8;24(1):1
Functional & integrative genomics 2023 Dec 8;24(1):1
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Yu W, Zhang Q, Qiu Y, Chen H, Huang X, Xiao L, Xu G, Li S, Hu P, Tong X
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
Aging 2023 Dec 27;15(24):15183-15195
Aging 2023 Dec 27;15(24):15183-15195
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Wang Z, Cai H, Li Z, Sun W, Zhao E, Cui H
Clinical epigenetics 2023 Dec 13;15(1):192
Clinical epigenetics 2023 Dec 13;15(1):192
Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.
Pan Z, Chen C, Huang X, Xiong Y, Kang X, Zhou J, Guo X, Zheng S, Wang C, Zheng F, Hu W
Neoplasma 2023 Aug;70(4):534-544
Neoplasma 2023 Aug;70(4):534-544
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34.
Wu J, Yue C, Xu W, Li H, Zhu J, Li L
Oncology letters 2023 Aug;26(2):325
Oncology letters 2023 Aug;26(2):325
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
Li J, Han J, Shi Y, Liu M
Experimental eye research 2023 Aug;233:109539
Experimental eye research 2023 Aug;233:109539
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
Wang M, Zhao M, Xu S, Zheng Z, Zhang J, Pan W, Yin Z, Liu J, Wei C, Wan J, Xu Y
Biochemical pharmacology 2023 Aug;214:115671
Biochemical pharmacology 2023 Aug;214:115671
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
Zhou Y, Zhang T, Wang S, Yang R, Jiao Z, Lu K, Li H, Jiang W, Zhang X
Pharmacological research 2023 Aug;194:106846
Pharmacological research 2023 Aug;194:106846
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071
The American journal of pathology 2023 Aug;193(8):1059-1071
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Zhou X, Li Y, Yang C, Chen D, Wang T, Liu T, Yan W, Su Z, Peng B, Ren X
Life sciences 2023 Aug 15;327:121698
Life sciences 2023 Aug 15;327:121698
ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.
Han S, Jin X, Hu T, Chi F
Carcinogenesis 2023 Aug 10;44(5):369-382
Carcinogenesis 2023 Aug 10;44(5):369-382
Anthraquinone metabolites isolated from the rhizosphere soil Streptomyces of Panax notoginseng (Burk.) F. H. Chen target MMP2 to inhibit cancer cell migration.
Xue JY, Wu YY, Han YL, Song XY, Zhang MY, Cheng J, Lin B, Xia MY, Zhang YX
Journal of ethnopharmacology 2023 Aug 10;312:116457
Journal of ethnopharmacology 2023 Aug 10;312:116457
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis.
Han Z, Hu H, Yin M, Lin Y, Yan Y, Han P, Liu B, Jing B
Molecular medicine (Cambridge, Mass.) 2023 Aug 1;29(1):104
Molecular medicine (Cambridge, Mass.) 2023 Aug 1;29(1):104
Knockdown of Krüppel-Like Factor 9 Inhibits Aberrant Retinal Angiogenesis and Mitigates Proliferative Diabetic Retinopathy.
Han N, Zhang L, Guo M, Yu L
Molecular biotechnology 2023 Apr;65(4):612-623
Molecular biotechnology 2023 Apr;65(4):612-623
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell.
Zhou W, Ma J, Zhao H, Wang Q, Guo X, Chen L, Cao Z, Xu J, Zhang B, Zhou X
Molecular & cellular proteomics : MCP 2023 Apr;22(4):100520
Molecular & cellular proteomics : MCP 2023 Apr;22(4):100520
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Lin S, Que Y, Que C, Li F, Deng M, Xu D
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.
Zhu S, Zhang X, Guo Y, Tang L, Zhou Z, Chen X, Peng C
Frontiers of medicine 2023 Apr;17(2):263-274
Frontiers of medicine 2023 Apr;17(2):263-274
Preclinical Evidence of Progesterone as a New Pharmacological Strategy in Human Adrenocortical Carcinoma Cell Lines.
Tamburello M, Abate A, Rossini E, Basnet RM, Zizioli D, Cosentini D, Hantel C, Laganà M, Tiberio GAM, Grisanti S, Memo M, Berruti A, Sigala S
International journal of molecular sciences 2023 Apr 6;24(7)
International journal of molecular sciences 2023 Apr 6;24(7)
Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation.
Jiang Y, Zhang M, Wang L, Zhang L, Ma M, Jing M, Li J, Song R, Zhang Y, Yang Z, Zhang Y, Pu Y, Qu X, Fan J
BMC complementary medicine and therapies 2023 Apr 17;23(1):122
BMC complementary medicine and therapies 2023 Apr 17;23(1):122
Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.
Hsu PL, Chien CW, Tang YA, Lin BW, Lin SC, Lin YS, Chen SY, Sun HS, Tsai SJ
Science advances 2023 Apr 14;9(15):eade3422
Science advances 2023 Apr 14;9(15):eade3422
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Zhu JX, Tang QQ, Zhou C, Shi XC, Yi SY, Yang Y
Frontiers in cardiovascular medicine 2022;9:808732
Frontiers in cardiovascular medicine 2022;9:808732
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone.
Silva A, Hatch CJ, Chu MT, Cardinal TR
Frontiers in cardiovascular medicine 2022;9:805810
Frontiers in cardiovascular medicine 2022;9:805810
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Lyu L, Cai Y, Zhang G, Jing Z, Liang J, Zhang R, Dang X, Zhang C
Frontiers in molecular biosciences 2022;9:1008802
Frontiers in molecular biosciences 2022;9:1008802
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
Li Y, Feng J, Bian Y, Cheng W, Qiao C
Folia histochemica et cytobiologica 2022;60(1):31-43
Folia histochemica et cytobiologica 2022;60(1):31-43
ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway.
Du T, Zhang K, Zhang Z, Guo A, Yu G, Xu Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2022;55:e11989
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2022;55:e11989
Orientin inhibits the progression of fibroblast-like synovial cells in rheumatoid arthritis by regulating MAPK-signaling pathway.
Ji W, Xu W
Allergologia et immunopathologia 2022;50(6):154-162
Allergologia et immunopathologia 2022;50(6):154-162
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Guan L, Wang F, Wang M, Han S, Cui Z, Xi S, Xu H, Li S
Oxidative medicine and cellular longevity 2022;2022:9613095
Oxidative medicine and cellular longevity 2022;2022:9613095
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Chen X, Zhang L, Geng J, Chen Z, Cui X
Journal of oncology 2022;2022:8267891
Journal of oncology 2022;2022:8267891
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R(-)/(-)) Mice.
Li W, Zhang H, Zhang L, Zhang T, Ding H
BioMed research international 2022;2022:7709926
BioMed research international 2022;2022:7709926
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
Liu J, Ding D, Liu F, Chen Y
BioMed research international 2022;2022:7184871
BioMed research international 2022;2022:7184871
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Tang R, Xiao G, Jian Y, Yuan Q, Jiang C, Wang W
Mediators of inflammation 2022;2022:6367264
Mediators of inflammation 2022;2022:6367264
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Xu J, Li Y, Li Z, Shao W, Song J, Wei J
Journal of oncology 2022;2022:3966386
Journal of oncology 2022;2022:3966386
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Han S, Lin F, Qi Y, Liu C, Zhou L, Xia Y, Chen K, Xing J, Liu Z, Yu W, Zhang Y, Zhou X, Rao T, Cheng F
Oxidative medicine and cellular longevity 2022;2022:3846217
Oxidative medicine and cellular longevity 2022;2022:3846217
IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression.
Chen H, Tang C, Tan C, Wu F, Li Z, Ji W, Lu L, Xu C, Shen Z, Huang Y
Journal of oncology 2022;2022:3445350
Journal of oncology 2022;2022:3445350
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
Wang F, Zhu L, Xue Q, Tang C, Tang W, Zhang N, Dai C, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1125932
Oxidative medicine and cellular longevity 2022;2022:1125932
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539
International journal of biological sciences 2022;18(6):2527-2539
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Qian W, Yang L, Ni Y, Yin F, Qin L, Yang Y
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells.
Wu K, Wu X, Liang Y, Wang T, Wu D, Li L, Wang Z
Frontiers in pharmacology 2022;13:922477
Frontiers in pharmacology 2022;13:922477
ABCA12 Promotes Proliferation and Migration and Inhibits Apoptosis of Pancreatic Cancer Cells Through the AKT Signaling Pathway.
Zheng S, Liu D, Wang F, Jin Y, Zhao S, Sun S, Wang S
Frontiers in genetics 2022;13:906326
Frontiers in genetics 2022;13:906326
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Li Y, Deng Y, Zhang X, Fu H, Han X, Guo W, Zhao W, Zhao X, Yu C, Li H, Lei K, Wang T
Frontiers in pharmacology 2022;13:897465
Frontiers in pharmacology 2022;13:897465
Kangfuxiaoyanshuan alleviates uterine inflammation and adhesion via inhibiting NF-κB p65 and TGF-β/MMP-2 signaling pathway in pelvic inflammatory disease rats.
Fan L, Liu Z, Zhang Z, Li T, Zong X, Bai H
Frontiers in pharmacology 2022;13:894149
Frontiers in pharmacology 2022;13:894149
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Wu Y, Chen M, Chen Z, Shu J, Zhang L, Hu J, Yu H, Huang K, Liang M
Frontiers in pharmacology 2022;13:861319
Frontiers in pharmacology 2022;13:861319
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
Halofuginone inhibits tumor migration and invasion by affecting cancer-associated fibroblasts in oral squamous cell carcinoma.
Wang D, Tian M, Fu Y, Sun Y, Ding L, Zhang X, Jing Y, Sun G, Ni Y, Song Y
Frontiers in pharmacology 2022;13:1056337
Frontiers in pharmacology 2022;13:1056337
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y
American journal of cancer research 2022;12(8):3892-3912
American journal of cancer research 2022;12(8):3892-3912
RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair.
Gou R, Li X, Dong H, Hu Y, Liu O, Liu J, Lin B
Frontiers in oncology 2022;12:936550
Frontiers in oncology 2022;12:936550
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.
Cheng J, Zhang Y, Wan R, Zhou J, Wu X, Fan Q, He J, Tan W, Deng Y
Frontiers in oncology 2022;12:919108
Frontiers in oncology 2022;12:919108
HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1.
Shu S, Li Z, Liu L, Ying X, Zhang Y, Wang T, Zhou X, Jiang P, Lv W
Frontiers in oncology 2022;12:900856
Frontiers in oncology 2022;12:900856
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Gong X, Liu X
Frontiers in oncology 2022;12:1054647
Frontiers in oncology 2022;12:1054647
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Li S, Hu Y, Liu O, Li X, Lin B
Frontiers in oncology 2022;12:1034737
Frontiers in oncology 2022;12:1034737
miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα.
Ma H, Wang X, Liu X, Wang C, Gao X, Niu J
Frontiers in cell and developmental biology 2022;10:841248
Frontiers in cell and developmental biology 2022;10:841248
Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis.
Jordan KR, Wyatt CR, Fallon ME, Woltjer R, Neuwelt EA, Cheng Q, Gailani D, Lorentz C, Tucker EI, McCarty OJT, Hinds MT, Nguyen KP
Journal of thrombosis and haemostasis : JTH 2022 Sep;20(9):2035-2045
Journal of thrombosis and haemostasis : JTH 2022 Sep;20(9):2035-2045
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.
Zhao W, Liu L, Li X, Xu S
International immunopharmacology 2022 Sep;110:109031
International immunopharmacology 2022 Sep;110:109031
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Chen W, Wang H, Lu Y, Huang Y, Xuan Y, Li X, Guo T, Wang C, Lai D, Wu S, Zhao W, Mai H, Li H, Wang B, Ma X, Zhang X
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
A Carabrane-Type Sesquiterpenolide Carabrone from Carpesium cernuum Inhibits SW1990 Pancreatic Cancer Cells by Inducing Ferroptosis.
Zheng YD, Zhang Y, Ma JY, Sang CY, Yang JL
Molecules (Basel, Switzerland) 2022 Sep 9;27(18)
Molecules (Basel, Switzerland) 2022 Sep 9;27(18)
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Xiao ZN, Guo DY, Yang J
Biology of reproduction 2022 Sep 12;107(3):834-845
Biology of reproduction 2022 Sep 12;107(3):834-845
LncRNA n339260 functions in hepatocellular carcinoma progression via regulation of miRNA30e-5p/TP53INP1 expression.
Liu T, Liao S, Mo J, Bai X, Li Y, Zhang Y, Zhang D, Cheng R, Zhao N, Che N, Guo Y, Dong X, Zhao X
Journal of gastroenterology 2022 Oct;57(10):784-797
Journal of gastroenterology 2022 Oct;57(10):784-797
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Ye C, Geng Z, Zhang LL, Zheng F, Zhou YB, Zhu GQ, Xiong XQ
Acta pharmacologica Sinica 2022 Oct;43(10):2573-2584
Acta pharmacologica Sinica 2022 Oct;43(10):2573-2584
MiR-582 Down-Regulates Lissencephaly-1 (LIS1) via P-Akt and MMP-2 to Inhibit Cholangiocarcinoma Cell Proliferation and Invasion.
Liu G, Li T, Ma L, Wang J, Yin Z
Iranian journal of biotechnology 2022 Oct;20(4):e3136
Iranian journal of biotechnology 2022 Oct;20(4):e3136
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
Lv S, Zhang Y, Song J, Chen J, Huang B, Luo Y, Zhao Y
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
Scinderin Is a Novel Oncogene for Its Correlates with Poor Prognosis, Immune Infiltrates and Matrix Metalloproteinase-2/9 (MMP2/9) in Glioma.
Wang Y, Li Z, Bai L, Zhang D, Zhang T, Ren F
Brain sciences 2022 Oct 20;12(10)
Brain sciences 2022 Oct 20;12(10)
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Wang T, Liu J, Huang X, Zhang C, Shangguan M, Chen J, Wu S, Chen M, Yang Z, Zhao S
Oncology reports 2022 Nov;48(5)
Oncology reports 2022 Nov;48(5)
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Tai S, Sun J, Zhou Y, Zhu Z, He Y, Chen M, Yang H, Xiao Y, Tu T, Tang L, Li X, Zeng J, Zheng X, Zhou S
Journal of advanced research 2022 Nov;41:205-218
Journal of advanced research 2022 Nov;41:205-218
STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer.
Yu S, E C, Yang J
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Nov;22(7):1003-1012
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Nov;22(7):1003-1012
Taraxasterol inhibits inflammation in osteoarthritis rat model by regulating miRNAs and NF-κB signaling pathway.
Xie Z, Wang B, Zheng C, Qu Y, Xu J, Wang B, Gao Y, Shen P
Acta biochimica Polonica 2022 Nov 26;69(4):811-818
Acta biochimica Polonica 2022 Nov 26;69(4):811-818
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
Lin L, Gao Y, Hu X, Ouyang J, Liu C
BMC women's health 2022 Nov 24;22(1):470
BMC women's health 2022 Nov 24;22(1):470
METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m(7)G-modified miR-760-dependent manner.
Xie H, Wang M, Yu H, Wang H, Ding L, Wang R, Luo W, Lu Z, Zheng Q, Ren L, Zhou Z, Su W, Xia L, Li G
Cell death discovery 2022 Nov 17;8(1):458
Cell death discovery 2022 Nov 17;8(1):458
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Zhang X, Li X, Xiong G, Yun F, Feng Y, Ni Q, Wu N, Yang L, Yi Z, Zhang Q, Yang Z, Kuang Y, Sai B, Zhu Y
Metabolites 2022 Nov 17;12(11)
Metabolites 2022 Nov 17;12(11)
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Zhang H, Liu J, Dang Q, Wang X, Chen J, Lin X, Yang N, Du J, Shi H, Liu Y, Han J
BMC molecular and cell biology 2022 Nov 16;23(1):48
BMC molecular and cell biology 2022 Nov 16;23(1):48
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Zhou W, Fu Y, Xu JS
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation.
Cui Z, Sun S, Li J, Li J, Sha T, He J, Zuo L
Cell biology international 2022 May;46(5):806-818
Cell biology international 2022 May;46(5):806-818
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
Zhang Y, Hui J, Xu Y, Ma Y, Sun Z, Zhang M, Nie L, Ye L
Chemosphere 2022 May;295:133925
Chemosphere 2022 May;295:133925
The programmed site-specific delivery of LY3200882 and PD-L1 siRNA boosts immunotherapy for triple-negative breast cancer by remodeling tumor microenvironment.
Zhang P, Qin C, Liu N, Zhou X, Chu X, Lv F, Gu Y, Yin L, Liu J, Zhou J, Huo M
Biomaterials 2022 May;284:121518
Biomaterials 2022 May;284:121518
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification.
Zhang X, Lai K, Li S, Wang J, Li J, Wang W, Ni S, Lu B, Grzybowski A, Ji J, Han H, Yao K
Bioactive materials 2022 Mar;9:343-357
Bioactive materials 2022 Mar;9:343-357
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Xu Y, Shi H, Wang M, Huang P, Xu M, Han S, Li H, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):247
Experimental and therapeutic medicine 2022 Mar;23(3):247
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Li H, You S, Yang X, Liu S, Hu L
Biomaterials advances 2022 Mar;134:112715
Biomaterials advances 2022 Mar;134:112715
Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu).
Gao X, Fan X, Zeng W, Liang J, Guo N, Yang X, Zhao Y
Bioengineered 2022 Mar;13(3):7881-7893
Bioengineered 2022 Mar;13(3):7881-7893
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Jiang Q, Wang Z, Qi Q, Li J, Xin Y, Qiu J
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Zhu M, Niu J, Jiang J, Dong T, Chen Y, Yang X, Liu P
Life sciences 2022 Mar 15;293:120358
Life sciences 2022 Mar 15;293:120358
Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.
Zhou GX, Liu WB, Dai LM, Zhu HL, Xiong YW, Li DX, Xu DX, Wang H
The Science of the total environment 2022 Mar 1;810:152247
The Science of the total environment 2022 Mar 1;810:152247
Early mobilization in spinal cord injury promotes changes in microglial dynamics and recovery of motor function.
Asano K, Nakamura T, Funakoshi K
IBRO neuroscience reports 2022 Jun;12:366-376
IBRO neuroscience reports 2022 Jun;12:366-376
Dexamethasone attenuated thoracic aortic aneurysm and dissection in vascular smooth muscle cell Tgfbr2-disrupted mice with CCL8 suppression.
Wang X, Li Q, Li W, Zhang T, Li X, Jiao Y, Zhang X, Jiang J, Zhang X, Zhang X
Experimental physiology 2022 Jun;107(6):631-645
Experimental physiology 2022 Jun;107(6):631-645
The molecular mechanism of baicalein repressing progression of gastric cancer mediating miR-7/FAK/AKT signaling pathway.
Qiao D, Xing J, Duan Y, Wang S, Yao G, Zhang S, Jin J, Lin Z, Chen L, Piao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154046
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154046
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Xi P, Niu Y, Zhang Y, Li W, Gao F, Gu W, Kui F, Liu Z, Lu L, Du G
Journal of ethnopharmacology 2022 Jun 28;292:115138
Journal of ethnopharmacology 2022 Jun 28;292:115138
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
Wang D, Zhang Y, Cui L, Yang Q, Wang J
Molecular and cellular endocrinology 2022 Jun 15;550:111647
Molecular and cellular endocrinology 2022 Jun 15;550:111647
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
Li N, Du H, Mao L, Xu G, Zhang M, Fan Y, Dong X, Zheng L, Wang B, Qin X, Jiang X, Chen C, Zou Z, Zhang J
Journal of nanobiotechnology 2022 Jun 11;20(1):270
Journal of nanobiotechnology 2022 Jun 11;20(1):270
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Yao N, Zhou J, Song J, Jiang Y, Zhang J
Neoplasma 2022 Jul;69(4):764-775
Neoplasma 2022 Jul;69(4):764-775
Circ_0076305 facilitates prostate cancer development via sponging miR-411-5p and regulating PGK1.
Ding X, Sun J, Zhang X
Andrologia 2022 Jul;54(6):e14406
Andrologia 2022 Jul;54(6):e14406
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
Chang S, Wen J, Su Y, Ma H
Electrophoresis 2022 Jul;43(13-14):1466-1475
Electrophoresis 2022 Jul;43(13-14):1466-1475
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Zheng Z, Guo Z, Zhong F, Wang B, Liu L, Ma W, Yu CY, Wei H
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:127-142
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:127-142
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway.
Jia N, Ma H, Zhang T, Wang L, Cui J, Zha Y, Ding Y, Wang J
International immunopharmacology 2022 Jul;108:108854
International immunopharmacology 2022 Jul;108:108854
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Wu W, Su Y, Hu C, Tao H, Jiang Y, Zhu G, Zhu J, Zhai Y, Qu J, Zhou X, Zhao F
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Chen J, Duan Z, Liu Y, Fu R, Zhu C
Nutrients 2022 Jul 25;14(15)
Nutrients 2022 Jul 25;14(15)
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Zhao C, Miao J, Sun R, Liang R, Chen W, Gao Y, Wang X, Han S, Zhao W, Lei T, Huang C
Aging 2022 Jul 22;14(14):5878-5894
Aging 2022 Jul 22;14(14):5878-5894
Identifying the anti-metastasis effect of Anhydroicaritin on breast cancer: Coupling network pharmacology with experimental validation.
Shi Y, Wu Y, Li F, Zhang Y, Hua C, Yang J, Zheng J, Chen L, Wei Z, Yue H, Sun C, Zhou X, Liu S
Journal of ethnopharmacology 2022 Jul 15;293:115326
Journal of ethnopharmacology 2022 Jul 15;293:115326
Combination of mitochondria impairment and inflammation blockade to combat metastasis.
Yi X, Yan Y, Li L, Zhou R, Shen X, Huang Y
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:753-768
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:753-768
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
Fan XZ, Wang YY, Cui ZY, Cheng ZH, Zhang HL, Gamper N, Zhang F, Han M
Free radical biology & medicine 2022 Jan;178:111-124
Free radical biology & medicine 2022 Jan;178:111-124
MiR-665 suppresses the progression of diffuse large B cell lymphoma (DLBCL) through targeting LIM and SH3 protein 1 (LASP1).
Wang Y, Guo D, Li B, Wang Y, Wang B, Wang Z, Wang M, Teng Q
Leukemia research 2022 Jan;112:106769
Leukemia research 2022 Jan;112:106769
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Zhang B, Zhu Z, Zhang X, Li F, Ding A
Translational andrology and urology 2022 Jan;11(1):53-66
Translational andrology and urology 2022 Jan;11(1):53-66
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
Cheng Y, Heng X, Feng F
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Zheng T, Zhou Y, Xu X, Qi X, Liu J, Pu Y, Zhang S, Gao X, Luo X, Li M, Wang X, Dong L, Wang Y, Mao C
Journal of translational medicine 2022 Jan 6;20(1):20
Journal of translational medicine 2022 Jan 6;20(1):20
Salidroside Promotes Sensitization to Doxorubicin in Human Cancer Cells by Affecting the PI3K/Akt/HIF Signal Pathway and Inhibiting the Expression of Tumor-Resistance-Related Proteins.
Zeng Q, Nie X, Li L, Liu HF, Peng YY, Zhou WT, Hu XJ, Xu XY, Chen XL
Journal of natural products 2022 Jan 28;85(1):196-204
Journal of natural products 2022 Jan 28;85(1):196-204
TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer.
Chen Y, Chen D, Qin Y, Qiu C, Zhou Y, Dai M, Li L, Sun Q, Jiang Y
Cell death discovery 2022 Jan 24;8(1):35
Cell death discovery 2022 Jan 24;8(1):35
Role of Periostin Expression in Non-Small Cell Lung Cancer: Periostin Silencing Inhibits the Migration and Invasion of Lung Cancer Cells via Regulation of MMP-2 Expression.
Ratajczak-Wielgomas K, Kmiecik A, Dziegiel P
International journal of molecular sciences 2022 Jan 22;23(3)
International journal of molecular sciences 2022 Jan 22;23(3)
Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension.
Guo M, Zhang M, Cao X, Fang X, Li K, Qin L, He Y, Zhao J, Xu Y, Liu X, Li X
Respiratory research 2022 Jan 11;23(1):6
Respiratory research 2022 Jan 11;23(1):6
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Niu X, Wang X, Niu B, Wang Y, He H, Li G
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
Xu P, Wang H, Pan H, Chen J, Deng C
Cancer chemotherapy and pharmacology 2022 Feb;89(2):183-196
Cancer chemotherapy and pharmacology 2022 Feb;89(2):183-196
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
Sun X, Hou Z, Li N, Zhang S
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Zhuang J, Hao J, Bu F, Yin H, Chen W, Guo H
Pathology, research and practice 2022 Feb;230:153752
Pathology, research and practice 2022 Feb;230:153752
Lectin-type oxidized LDL receptor 1 modulates matrix metalloproteinase 2 production in peri-implantitis.
Zhang Q, Xu T, Bai N, Tan F, Zhao H, Liu J
Experimental and therapeutic medicine 2022 Feb;23(2):171
Experimental and therapeutic medicine 2022 Feb;23(2):171
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Du X, Li C, Zhang S, Sun C, Zhang X, Chen C, Wang X, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114507
Journal of ethnopharmacology 2022 Feb 10;284:114507
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
Wang J, Wang B, Zhou B, Chen J, Qi J, Shi L, Yu S, Chen G, Kang M, Jin X, Wang L, Xu J, Zhu L, Chen J
Cancer cell international 2022 Feb 10;22(1):69
Cancer cell international 2022 Feb 10;22(1):69
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
Li CM, Wu W, Zhu Z, Lu PL, Gong JP, Ma R
Neoplasma 2022 Dec;69(6):1359-1372
Neoplasma 2022 Dec;69(6):1359-1372
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer.
Lu D, Lin Z, Wang R, Chen Z, Zhuo J, Xu L, Pan L, Li H, Yang X, He C, Shen W, Yang M, Li H, Chen H, Tan W, Wei X, Zheng S, Xu X
Redox biology 2022 Dec;58:102538
Redox biology 2022 Dec;58:102538
Treatment of malignant pleural effusion in non-small cell lung cancer with VEGF-directed therapy.
Xiang Z, Deng X, He W, Yang Q, Ni L, Dehghan Shasaltaneh M, Maghsoudloo M, Yang G, Wu J, Imani S, Wen Q
Annals of medicine 2022 Dec;54(1):1357-1371
Annals of medicine 2022 Dec;54(1):1357-1371
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
Effect of hydroxychloroquine on antiphospholipid antibodies-inhibited endometrial angiogenesis.
Dong Y, Lu Y, Xia Y, Wang X
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Dec;35(25):7084-7092
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Dec;35(25):7084-7092
Exosomal microRNA-133b-3p from bone marrow mesenchymal stem cells inhibits angiogenesis and oxidative stress via FBN1 repression in diabetic retinopathy.
Liang G, Qin Z, Luo Y, Yin J, Shi Z, Wei R, Ma W
Gene therapy 2022 Dec;29(12):710-719
Gene therapy 2022 Dec;29(12):710-719
miR-4443/MMP2 suppresses the migration and invasion of trophoblasts through the HB-EGF/EGFR pathway in preeclampsia.
Chen C, Gao J, Chen D, Liu J, He B, Chen Y, Zhang H, Yang X, Cheng W
Cell cycle (Georgetown, Tex.) 2022 Dec;21(23):2517-2532
Cell cycle (Georgetown, Tex.) 2022 Dec;21(23):2517-2532
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Gu X, Liu H, Luo W, Wang X, Wang H, Li L
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Zhang S, Cao S, Gong M, Zhang W, Zhang W, Zhu Z, Wu S, Yue Y, Qian W, Ma Q, Wang S, Wang Z
Cancer biology & therapy 2022 Dec 31;23(1):336-347
Cancer biology & therapy 2022 Dec 31;23(1):336-347
Krüppel-like Factor 6 Suppresses the Progression of Pancreatic Cancer by Upregulating Activating Transcription Factor 3.
Xiong Q, Zhang Z, Yang Y, Xu Y, Zhou Y, Zhang S, Liu J, Zheng Y, Zhu Q
Journal of clinical medicine 2022 Dec 27;12(1)
Journal of clinical medicine 2022 Dec 27;12(1)
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
Chewing Behavior Attenuates Lung-Metastasis-Promoting Effects of Chronic Stress in Breast-Cancer Lung-Metastasis Model Mice.
Zhang JH, Wang KY, Kubo KY, Azuma K
Cancers 2022 Dec 1;14(23)
Cancers 2022 Dec 1;14(23)
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Su SB, Tao L, Liang XL, Chen W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Zhang B, Liu ZY, Wu R, Zhang CM, Cao K, Shan WG, Liu Z, Ji M, Tian ZL, Sethi G, Shi HL, Wang RH
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Zhang Y, Cao L, Xie Y, Wang C, Liu X, Zhang X, Chen J
Experimental and therapeutic medicine 2022 Aug;24(2):490
Experimental and therapeutic medicine 2022 Aug;24(2):490
The miR-410-5p /ITGA6 axis participates in the pathogenesis of recurrent abortion by regulating the biological function of trophoblast.
Wu S, Liu H, Zhou M, Shang Y, Luo L, Chen J, Yang J
Journal of reproductive immunology 2022 Aug;152:103647
Journal of reproductive immunology 2022 Aug;152:103647
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
Chen YC, Chang HN, Pang JS, Lin LP, Chen JM, Yu TY, Tsai WC
International journal of molecular sciences 2022 Aug 7;23(15)
International journal of molecular sciences 2022 Aug 7;23(15)
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Jia X, Xin M, Xu J, Xiang X, Li X, Jiao Y, Wang L, Jiang J, Pang F, Zhang X, Zhang J
Cell death & disease 2022 Aug 30;13(8):750
Cell death & disease 2022 Aug 30;13(8):750
Sparstolonin B inhibits pancreatic adenocarcinoma through the NF-κB signaling pathway.
Lyu Y, Duan B, Liu Z, Yang F, Chen C, Jiang X, Liu X
Experimental cell research 2022 Aug 1;417(1):113214
Experimental cell research 2022 Aug 1;417(1):113214
SEZ6L2, regulated by USF1, accelerates the growth and metastasis of breast cancer.
Chen L, Han S, Li Y, Zheng Y, Zhang Q
Experimental cell research 2022 Aug 1;417(1):113194
Experimental cell research 2022 Aug 1;417(1):113194
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
LINC00982 Inhibits the Proliferation, Migration, and Invasion of Breast Cancer Cells Through the miR-765/DPF3 Axis.
Chi F, Qiu F, Jin X, Chen L, He G, Han S
DNA and cell biology 2022 Apr;41(4):424-436
DNA and cell biology 2022 Apr;41(4):424-436
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
Wang C, Wang Y, Liu C, Meng X, Hang Z
Bioengineered 2022 Apr;13(4):9495-9507
Bioengineered 2022 Apr;13(4):9495-9507
METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X, Huang Y, Zhu W, Wang J, Wen J, Meng X, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1721-1740
miR-340-5p affects oral squamous cell carcinoma (OSCC) cells proliferation and invasion by targeting endoplasmic reticulum stress proteins.
Ou D, Wu Y, Zhang J, Liu J, Liu Z, Shao M, Guo X, Cui S
European journal of pharmacology 2022 Apr 5;920:174820
European journal of pharmacology 2022 Apr 5;920:174820
Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway.
Li F, Shi Y, Zhang Y, Yang X, Wang Y, Jiang K, Hua C, Wu C, Sun C, Qin Y, Liu S
Chinese medicine 2022 Apr 4;17(1):44
Chinese medicine 2022 Apr 4;17(1):44
LINC00022 acts as an oncogene in colorectal cancer progression via sponging miR-375-3p to regulate FOXF1 expression.
Xu L, He H, Shang Y, Qu X, Sun J
BMC cancer 2022 Apr 26;22(1):453
BMC cancer 2022 Apr 26;22(1):453
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M
Cell death & disease 2022 Apr 18;13(4):358
Cell death & disease 2022 Apr 18;13(4):358
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
Chen Y, Zhou X, Huang S, Lan Y, Yan R, Shi X, Li X, Zhang Y, Lei Z, Fan D
Frontiers in bioengineering and biotechnology 2021;9:793778
Frontiers in bioengineering and biotechnology 2021;9:793778
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
Wang W, Zhou M, Xu Y, Peng W, Zhang S, Li R, Zhang H, Zhang H, Cheng S, Wang Y, Wei X, Yue C, Yang Q, Chen C
Frontiers in bioengineering and biotechnology 2021;9:762489
Frontiers in bioengineering and biotechnology 2021;9:762489
Circular RNA CircPPP1CB Suppresses Tumorigenesis by Interacting With the MiR-1307-3p/SMG1 Axis in Human Bladder Cancer.
Wang F, Zhang Y, Zhou X, Chen X, Xiang J, Fan M, Yu Y, Cai Y, Wu H, Huang S, He N, Hu Z, Ding G, Jin X
Frontiers in cell and developmental biology 2021;9:704683
Frontiers in cell and developmental biology 2021;9:704683
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Liu H, Zhang Y, Song W, Sun Y, Jiang Y
Frontiers in cell and developmental biology 2021;9:681790
Frontiers in cell and developmental biology 2021;9:681790
Cancer-Associated Fibroblasts Promote Vascular Invasion of Hepatocellular Carcinoma via Downregulating Decorin-integrin β1 Signaling.
Zheng X, Wang P, Li L, Yu J, Yu C, Xu L, Li L, Dai F, Feng L, Zou H, Chen X, Zhang M, Xu M
Frontiers in cell and developmental biology 2021;9:678670
Frontiers in cell and developmental biology 2021;9:678670
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J
Nutrition and cancer 2021;73(8):1459-1470
Nutrition and cancer 2021;73(8):1459-1470
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Qiao D, Jin J, Xing J, Zhang Y, Jia N, Ren X, Lin Z, Jin N, Chen L, Piao Y
The American journal of Chinese medicine 2021;49(2):525-541
The American journal of Chinese medicine 2021;49(2):525-541
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Ji J, Yu Q, Dai W, Wu L, Feng J, Zheng Y, Li Y, Guo C
PPAR research 2021;2021:6651839
PPAR research 2021;2021:6651839
The Mechanism of miR-141 Regulating the Proliferation and Metastasis of Liver Cancer Cells by Targeting STAT4.
Ma L, Shao H, Chen H, Deng Q
Journal of oncology 2021;2021:5425491
Journal of oncology 2021;2021:5425491
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Yuan C, Bai R, Gao Y, Jiang X, Li S, Sun W, Li Y, Huang Z, Gong Y, Xie C
Oxidative medicine and cellular longevity 2021;2021:4522210
Oxidative medicine and cellular longevity 2021;2021:4522210
miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1.
Li D, Zhang Y, Li Y, Wang X, Wang F, Du J, Zhang H, Shi H, Wang Y, Gao Y, Feng Y, Yan J, Xue Y, Yang Y, Zhang J
BioMed research international 2021;2021:1503403
BioMed research international 2021;2021:1503403
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952
OncoTargets and therapy 2021;14:2941-2952
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Niu HT, Liu Y, Wang YZ, Tian Y, Yang M, Jiang HS
Cancer management and research 2021;13:489-497
Cancer management and research 2021;13:489-497
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Liu O, Wang C, Wang S, Hu Y, Gou R, Dong H, Li S, Li X, Lin B
Journal of Cancer 2021;12(22):6835-6850
Journal of Cancer 2021;12(22):6835-6850
Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells.
Nie X, Gao L, Zheng M, Wang C, Wang S, Li X, Qi Y, Zhu L, Liu J, Lin B
Journal of Cancer 2021;12(19):5772-5788
Journal of Cancer 2021;12(19):5772-5788
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Ye J, Qi L, Liang J, Zong K, Liu W, Li R, Feng R, Zhai W
Journal of Cancer 2021;12(12):3548-3557
Journal of Cancer 2021;12(12):3548-3557
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Huang YN, Xu YY, Ma Q, Li MQ, Guo JX, Wang X, Jin X, Shang J, Jiao LX
Journal of Cancer 2021;12(11):3367-3377
Journal of Cancer 2021;12(11):3367-3377
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Pan J, Cao Z, Fang C, Lei Y, Sun J, Huang X, Han D
Frontiers in pharmacology 2021;12:722530
Frontiers in pharmacology 2021;12:722530
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in pharmacology 2021;12:703962
Frontiers in pharmacology 2021;12:703962
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Aihaiti Y, Song Cai Y, Tuerhong X, Ni Yang Y, Ma Y, Shi Zheng H, Xu K, Xu P
Frontiers in pharmacology 2021;12:672054
Frontiers in pharmacology 2021;12:672054
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Wang Y, Shen H, Sun Q, Zhao L, Liu H, Ye L, Xu Y, Cai J, Li Y, Gao L, Tan Y, Liu B, Chen Q
Frontiers in pharmacology 2021;12:659511
Frontiers in pharmacology 2021;12:659511
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
Zhu X, Liu S, Yang X, Wang W, Shao W, Ji T
American journal of cancer research 2021;11(2):590-617
American journal of cancer research 2021;11(2):590-617
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, Hu H, Chen T, Tan B
Frontiers in oncology 2021;11:704001
Frontiers in oncology 2021;11:704001
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
Zhao Y, Zhou H, Shen J, Yang S, Deng K, Li Q, Cui W
Frontiers in oncology 2021;11:688882
Frontiers in oncology 2021;11:688882
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
Wang J, Li H, Wang L, Zhang J, Li M, Qiao L, Zhang J, Liu L, Zhang C, Gao J, Li W
Frontiers in oncology 2021;11:681250
Frontiers in oncology 2021;11:681250
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Shi S, Li C, Zhang Y, Deng C, Liu W, Du J, Li Q, Ji Y, Guo L, Liu L, Hu H, Liu Y, Cui H
Frontiers in oncology 2021;11:648052
Frontiers in oncology 2021;11:648052
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Nisar MA, Zheng Q, Saleem MZ, Ahmmed B, Ramzan MN, Ud Din SR, Tahir N, Liu S, Yan Q
Frontiers in oncology 2021;11:618839
Frontiers in oncology 2021;11:618839
Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke.
Liu B, Li Y, Han Y, Wang S, Yang H, Zhao Y, Li P, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153660
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153660
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Zhao ZQ, Wu XJ, Cheng YH, Zhou YF, Ma XM, Zhang J, Heng XY, Feng F
CNS neuroscience & therapeutics 2021 Sep;27(9):1064-1076
CNS neuroscience & therapeutics 2021 Sep;27(9):1064-1076
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Ma Y, Xia P, Wang Z, Xu J, Zhang L, Jiang Y
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
Miao Y, Wang X, Lai Y, Lin W, Huang Y, Yin H, Hou R, Zhang F
Oncology letters 2021 Sep;22(3):686
Oncology letters 2021 Sep;22(3):686
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Yan L, He Z, Li W, Liu N, Gao S
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Li H, Yang W, Zhang M, He T, Zhou F, G Herman J, Hu L, Guo M
Epigenomics 2021 Sep;13(17):1403-1419
Epigenomics 2021 Sep;13(17):1403-1419
Induction of Apoptosis and Inhibition of EGFR/NF-κB Signaling Are Associated With Regorafenib-sensitized Non-small Cell Lung Cancer to Cisplatin.
Wu JY, Weng YS, Chiou YC, Hsu FT, Chiang IT
In vivo (Athens, Greece) 2021 Sep-Oct;35(5):2569-2576
In vivo (Athens, Greece) 2021 Sep-Oct;35(5):2569-2576
Integrative analysis of genome-wide DNA methylation and single-nucleotide polymorphism identified ACSM5 as a suppressor of lumbar ligamentum flavum hypertrophy.
Cao Y, Zhan Y, Qiu S, Chen Z, Gong K, Ni S, Duan Y
Arthritis research & therapy 2021 Sep 30;23(1):251
Arthritis research & therapy 2021 Sep 30;23(1):251
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Kuang H, Wang T, Liu L, Tang C, Li T, Liu M, Wang T, Zhong W, Wang Y
Neuroscience letters 2021 Sep 25;762:136134
Neuroscience letters 2021 Sep 25;762:136134
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Zou Y, Pan L, Shen Y, Wang X, Huang C, Wang H, Jin X, Yin C, Wang Y, Jia J, Qian J, Zou Y, Gong H, Ge J
Cell death & disease 2021 Sep 25;12(10):877
Cell death & disease 2021 Sep 25;12(10):877
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Niu X, Wang X, Niu B, Meng Y, He H, Wang Y, Li G
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Huang Y, Zhang H, Wang L, Liu C, Guo M, Tan H, Liu Z
Cancer cell international 2021 Sep 16;21(1):494
Cancer cell international 2021 Sep 16;21(1):494
Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness.
Lu X, Zhang H, Wang M, Qu F, Li J, Li R, Yan X
Ecotoxicology and environmental safety 2021 Sep 15;221:112440
Ecotoxicology and environmental safety 2021 Sep 15;221:112440
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225
International journal of cardiology 2021 Sep 1;338:215-225
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Yu S, Wang S, Sun X, Wu Y, Zhao J, Liu J, Yang D, Jiang Y
Oncology letters 2021 Oct;22(4):736
Oncology letters 2021 Oct;22(4):736
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Guan X, Yu D, HuangFu M, Huang Z, Dou T, Liu Y, Zhou L, Li X, Wang L, Liu H, Wang J, Chen X
Biochemical pharmacology 2021 Oct;192:114742
Biochemical pharmacology 2021 Oct;192:114742
Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90.
Li HM, Ma H, Sun X, Li B, Cao C, Dai Y, Zhu M, Wu CZ
Molecules (Basel, Switzerland) 2021 Oct 30;26(21)
Molecules (Basel, Switzerland) 2021 Oct 30;26(21)
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway.
He D, Gao J, Zheng L, Liu S, Ye L, Lai H, Pan B, Pan W, Lou C, Chen Z, Fan S
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Lu ZN, Niu WX, Zhang N, Ge MX, Bao YY, Ren Y, Guo XL, He HW
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X, Cui X
Balkan medical journal 2021 Nov;38(6):331-340
Balkan medical journal 2021 Nov;38(6):331-340
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression.
Sun Y, Ma G, Xiang H, Wang X, Wang H, Zhang Y, Qie F, Li C
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
An inducible rodent glaucoma model that exhibits gradual sustained increase in intraocular pressure with distinct inner retina and optic nerve inflammation.
Mathew DJ, Livne-Bar I, Sivak JM
Scientific reports 2021 Nov 24;11(1):22880
Scientific reports 2021 Nov 24;11(1):22880
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Ma Y, Kuang Y, Bo W, Liang Q, Zhu W, Cai M, Tian Z
International journal of molecular sciences 2021 Nov 15;22(22)
International journal of molecular sciences 2021 Nov 15;22(22)
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong L, Ma Y, Wang Z, Liu N, Ma G, Liu C, Shi R, Du G
International immunopharmacology 2021 May;94:107507
International immunopharmacology 2021 May;94:107507
Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.
Cheng XB, Zhang T, Zhu HJ, Ma N, Sun XD, Wang SH, Jiang Y
Neoplasma 2021 May;68(3):546-556
Neoplasma 2021 May;68(3):546-556
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Ren K, Li B, Liu Z, Xia L, Zhai M, Wei X, Duan W, Yu S
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Zhang D, Huang J, Wang F, Ding H, Cui Y, Yang Y, Xu J, Luo H, Gao Y, Pan L, Wu Y, Gong Y, Xie L, Liu Z, Qu Y, Zhang L, Liu W, Zhang W, Zhao S, Yi Q, Niu T, Zheng Y
Cell death & disease 2021 May 15;12(5):495
Cell death & disease 2021 May 15;12(5):495
A reproducible swine model of a surgically created saccular thoracic aortic aneurysm.
Fukushima S, Ohki T, Koizumi M, Ohta H, TakahasHi T, Okano HJ
Experimental animals 2021 May 13;70(2):257-263
Experimental animals 2021 May 13;70(2):257-263
L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail.
Fan X, Zhou J, Bi X, Liang J, Lu S, Yan X, Luo L, Yin Z
The Journal of nutritional biochemistry 2021 Mar;89:108556
The Journal of nutritional biochemistry 2021 Mar;89:108556
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Amentoflavone Induces Cell-cycle Arrest, Apoptosis, and Invasion Inhibition in Non-small Cell Lung Cancer Cells.
Chen WT, Chen CH, Su HT, Yueh PF, Hsu FT, Chiang IT
Anticancer research 2021 Mar;41(3):1357-1364
Anticancer research 2021 Mar;41(3):1357-1364
Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4.
Aronovich A, Moyal L, Gorovitz B, Amitay-Laish I, Naveh HP, Forer Y, Maron L, Knaneh J, Ad-El D, Yaacobi D, Barel E, Erez N, Hodak E
The Journal of investigative dermatology 2021 Mar;141(3):619-627.e2
The Journal of investigative dermatology 2021 Mar;141(3):619-627.e2
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Choi MH, Kim J, Ha JH, Park JU
Scientific reports 2021 Mar 9;11(1):5468
Scientific reports 2021 Mar 9;11(1):5468
Bone marrow stem cells secretome accelerates simulated birth trauma-induced stress urinary incontinence recovery in rats.
Jiang M, Liu J, Liu W, Zhu X, Bano Y, Liao H, Li H, Jiang HH
Aging 2021 Mar 31;13(7):10517-10534
Aging 2021 Mar 31;13(7):10517-10534
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Cvetanova B, Li MY, Yang CC, Hsiao PW, Yang YC, Feng JH, Shen YC, Nakagawa-Goto K, Lee KH, Shyur LF
International journal of molecular sciences 2021 Mar 22;22(6)
International journal of molecular sciences 2021 Mar 22;22(6)
The essential role of PRAK in tumor metastasis and its therapeutic potential.
Wang Y, Wang W, Wu H, Zhou Y, Qin X, Wang Y, Wu J, Sun XY, Yang Y, Xu H, Qian X, Pang X, Li Y, Zhang Z, Han J, Zhang Y
Nature communications 2021 Mar 19;12(1):1736
Nature communications 2021 Mar 19;12(1):1736
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
Que ZJ, Yang Y, Liu HT, Shang-Guan WJ, Yu P, Zhu LH, Li HG, Liu HM, Tian JH
Journal of ethnopharmacology 2021 Mar 1;267:113473
Journal of ethnopharmacology 2021 Mar 1;267:113473
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Lenvatinib Induces AKT/NF-κB Inactivation, Apoptosis Signal Transduction and Growth Inhibition of Non-small Cell Lung Cancer In Vivo.
Liu YC, Hsu FT, Chung JG, Weng MC, Ting CY, Tsai CJ, Lan A, Wu JY, Lin CC, Lin SS
Anticancer research 2021 Jun;41(6):2867-2874
Anticancer research 2021 Jun;41(6):2867-2874
Quercetin inhibits invasion and angiogenesis of esophageal cancer cells.
Liu Y, Li CL, Xu QQ, Cheng D, Liu KD, Sun ZQ
Pathology, research and practice 2021 Jun;222:153455
Pathology, research and practice 2021 Jun;222:153455
Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Que Y, Shu X, Wang L, Wang S, Li S, Hu P, Tong X
British journal of pharmacology 2021 Jun;178(11):2305-2323
British journal of pharmacology 2021 Jun;178(11):2305-2323
IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.
Chen Y, Qin Y, Dai M, Liu L, Ni Y, Sun Q, Li L, Zhou Y, Qiu C, Jiang Y
Cancer medicine 2021 Jun;10(12):4030-4045
Cancer medicine 2021 Jun;10(12):4030-4045
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
Li X, Wang C, Wang S, Hu Y, Jin S, Liu O, Gou R, Nie X, Liu J, Lin B
Cancer cell international 2021 Jun 9;21(1):302
Cancer cell international 2021 Jun 9;21(1):302
Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3β/ZEB1 pathway.
Lv F, Du Q, Li L, Xi X, Liu Q, Li W, Liu S
European journal of pharmacology 2021 Jun 5;900:174069
European journal of pharmacology 2021 Jun 5;900:174069
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Anti-tumor effects of Solanum nigrum L. extraction on C6 high-grade glioma.
Li JH, Li SY, Shen MX, Qiu RZ, Fan HW, Li YB
Journal of ethnopharmacology 2021 Jun 28;274:114034
Journal of ethnopharmacology 2021 Jun 28;274:114034
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway.
Yang F, Wang H, Yan B, Li T, Min L, Chen E, Yang J
Biological chemistry 2021 Jun 25;402(7):805-813
Biological chemistry 2021 Jun 25;402(7):805-813
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Liu X, Lv Z, Zhou S, Kan S, Liu X, Jing P, Xu W
International immunopharmacology 2021 Jul;96:107776
International immunopharmacology 2021 Jul;96:107776
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Liu X, Jin J, Liu Y, Shen Z, Zhao R, Ou L, Xing T
International immunopharmacology 2021 Jul;96:107618
International immunopharmacology 2021 Jul;96:107618
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
Xu K, Gao Y, Yang L, Liu Y, Wang C
Connective tissue research 2021 Jul;62(4):475-484
Connective tissue research 2021 Jul;62(4):475-484
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Du T, Wang D, Wan X, Xu J, Xiao Q, Liu B
Oncology letters 2021 Jul;22(1):516
Oncology letters 2021 Jul;22(1):516
Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
Sun XL, Zhu ML, Dai YQ, Li HM, Li BH, Ma H, Zhang CH, Wu CZ
Molecules (Basel, Switzerland) 2021 Jul 15;26(14)
Molecules (Basel, Switzerland) 2021 Jul 15;26(14)
Abiotic Mimic of Matrix Metalloproteinase-9 Inhibitor against Advanced Metastatic Cancer.
Zhang T, Dar KK, Li Y, Guo J, Sun W, Shea KJ, Tan T, Lv Y
ACS biomaterials science & engineering 2021 Jul 12;7(7):3190-3200
ACS biomaterials science & engineering 2021 Jul 12;7(7):3190-3200
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Chen S, Chen X, Qiu J, Chen P, Han X, Wu Y, Zhuang J, Yang M, Wu C, Wu N, Yang Y, Ge J, Yu K, Zhuang J
Oncology reports 2021 Jan;45(1):278-290
Oncology reports 2021 Jan;45(1):278-290
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Li Q, Chu Z, Geng S
Cancer investigation 2021 Jan;39(1):84-97
Cancer investigation 2021 Jan;39(1):84-97
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Zhang W, Feng G
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
Kiaa0101 serves as a prognostic marker and promotes invasion by regulating p38/snail1 pathway in glioma.
Liu J, Gao L, Liao J, Yang J, Yuan F, Chen Q
Annals of translational medicine 2021 Feb;9(3):260
Annals of translational medicine 2021 Feb;9(3):260
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Li C, Li Y, Lou L, Han X, Wang H, Huang T, Li C
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Lin L, Wang Q, Xu F, Luo X, Xu J, Yan L, Li Q, Hao H
Immunology letters 2021 Feb;230:27-35
Immunology letters 2021 Feb;230:27-35
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Guan JH, Cao ZY, Guan B, Wei LH, Peng J, Chen YQ, Sferra TJ, Sankararaman S, Zhan ZX, Lin JM
Translational cancer research 2021 Feb;10(2):953-965
Translational cancer research 2021 Feb;10(2):953-965
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
Liu Y, Wang D, Lei M, Gao J, Cui Y, Jin X, Yu Q, Jiang Y, Guo Y, Liu Y, Cai L, Chen X
Aging 2021 Feb 11;13(4):5858-5874
Aging 2021 Feb 11;13(4):5858-5874
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X, Cui X
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2.
Li B, Liu X, Wu G, Liu J, Cai S, Wang F, Yang C, Liu J
Bioengineered 2021 Dec;12(2):9507-9519
Bioengineered 2021 Dec;12(2):9507-9519
YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.
Sha T, Li J, Sun S, Li J, Zhao X, Li Z, Cui Z
Bioengineered 2021 Dec;12(1):7286-7296
Bioengineered 2021 Dec;12(1):7286-7296
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275.
Feng J, Li J, Qie P, Li Z, Xu Y, Tian Z
Bioengineered 2021 Dec;12(1):196-207
Bioengineered 2021 Dec;12(1):196-207
Expression of matrix metalloproteinases during axonal regeneration in the goldfish spinal cord.
Takeda A, Kanemura A, Funakoshi K
Journal of chemical neuroanatomy 2021 Dec;118:102041
Journal of chemical neuroanatomy 2021 Dec;118:102041
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway.
Zhao G, Shi X, Sun Z, Zhao P, Lu Z
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1602-1613
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1602-1613
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
Zhang X, He Y, Jiang Y, Bao Y, Chen Q, Xie D, Yu H, Wang X
Oncology reports 2021 Aug;46(2)
Oncology reports 2021 Aug;46(2)
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway.
Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, Yu H, Chen K, Hu Q, Xia X, Liu S, Guan W
Clinical and translational medicine 2021 Aug;11(8):e522
Clinical and translational medicine 2021 Aug;11(8):e522
Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway.
Wang D, Hu A, Peng H, Li D, Zhang L
3 Biotech 2021 Aug;11(8):380
3 Biotech 2021 Aug;11(8):380
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Chen X, Zhang W, Xu X
World journal of surgical oncology 2021 Aug 6;19(1):232
World journal of surgical oncology 2021 Aug 6;19(1):232
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
The protective effect of HOXA5 on carotid atherosclerosis occurs by modulating the vascular smooth muscle cell phenotype.
Jing Y, Gao B, Han Z, Xia L, Xin S
Molecular and cellular endocrinology 2021 Aug 20;534:111366
Molecular and cellular endocrinology 2021 Aug 20;534:111366
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Wang X, Zhang X, Qiu T, Yang Y, Li Q, Zhang X
Experimental cell research 2021 Aug 15;405(2):112703
Experimental cell research 2021 Aug 15;405(2):112703
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Liu J, Zhang Y, Yu C, Zhang P, Gu S, Wang G, Xiao H, Li S
Drug development research 2021 Apr;82(2):278-286
Drug development research 2021 Apr;82(2):278-286
Curcumol inhibits the viability and invasion of colorectal cancer cells via miR-30a-5p and Hippo signaling pathway.
Yu D, Liu H, Qin J, Huangfu M, Guan X, Li X, Zhou L, Dou T, Liu Y, Wang L, Fu M, Wang J, Chen X
Oncology letters 2021 Apr;21(4):299
Oncology letters 2021 Apr;21(4):299
Effects of blood oxygen saturation on pulmonary artery remodeling in an in vitro perfusion circuit model.
Liu Y, Wen B, Zhang F, Pan XB
Journal of thoracic disease 2021 Apr;13(4):2169-2176
Journal of thoracic disease 2021 Apr;13(4):2169-2176
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model.
Chen J, Zhang Y, Wang Y, Jiang P, Zhou G, Li Z, Yang J, Li X
Chinese medicine 2021 Apr 27;16(1):34
Chinese medicine 2021 Apr 27;16(1):34
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Guo S, Zhang B, Qi W, Cao X, Xu Y, Zhang X, Li X, Zhou L, Ye L
Toxicology 2021 Apr 15;453:152734
Toxicology 2021 Apr 15;453:152734
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Morusin Inhibits Human Osteosarcoma via the PI3K-AKT Signaling Pathway.
Zhang Y, Weng Q, Chen J, Han J
Current pharmaceutical biotechnology 2020;21(13):1402-1409
Current pharmaceutical biotechnology 2020;21(13):1402-1409
Overexpression of miR-29a-3p Suppresses Proliferation, Migration, and Invasion of Vascular Smooth Muscle Cells in Atherosclerosis via Targeting TNFRSF1A.
You L, Chen H, Xu L, Li X
BioMed research international 2020;2020:9627974
BioMed research international 2020;2020:9627974
Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells.
Xi Y, Nie X, Wang J, Gao L, Lin B
BioMed research international 2020;2020:3607436
BioMed research international 2020;2020:3607436
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, Xiong Z, Yang S
BioMed research international 2020;2020:3126182
BioMed research international 2020;2020:3126182
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Wang S, Wang C, Li X, Hu Y, Gou R, Guo Q, Nie X, Liu J, Zhu L, Lin B
Cancer cell international 2020;20:418
Cancer cell international 2020;20:418
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y
International journal of biological sciences 2020;16(4):708-718
International journal of biological sciences 2020;16(4):708-718
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
Liu H, Liao W, Fan L, Zheng Z, Liu D, Zhang QW, Yang A, Liu F
Chinese medicine 2020;15:11
Chinese medicine 2020;15:11
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
Zheng P, Li L
OncoTargets and therapy 2020;13:451-463
OncoTargets and therapy 2020;13:451-463
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Wu QQ, Zhao M, Huang GZ, Zheng ZN, Chen Y, Zeng WS, Lv XZ
OncoTargets and therapy 2020;13:2599-2611
OncoTargets and therapy 2020;13:2599-2611
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z
OncoTargets and therapy 2020;13:1993-2006
OncoTargets and therapy 2020;13:1993-2006
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
Yuan Q, Yu H, Chen J, Song X, Sun L
OncoTargets and therapy 2020;13:1637-1647
OncoTargets and therapy 2020;13:1637-1647
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Wang X, Song X, Cheng G, Zhang J, Dong L, Bai J, Luo D, Xiong Y, Li S, Liu F, Sun Y, Wang X, Li Y, Huang Y
OncoTargets and therapy 2020;13:11781-11794
OncoTargets and therapy 2020;13:11781-11794
Overexpression of TEM8 promotes ovarian cancer progression via Rac1/Cdc42/JNK and MEK/ERK/STAT3 signaling pathways.
Wang CX, Xiong HF, Wang S, Wang J, Nie X, Guo Q, Li X, Qi Y, Liu JJ, Lin B
American journal of translational research 2020;12(7):3557-3576
American journal of translational research 2020;12(7):3557-3576
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Lv Z, Wu K, Qin X, Yuan J, Yan M, Zhang J, Wang L, Ji T, Cao W, Chen W
Cancer management and research 2020;12:4855-4869
Cancer management and research 2020;12:4855-4869
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
Cui X, Zhang H, Cao A, Cao L, Hu X
Journal of Cancer 2020;11(7):1800-1807
Journal of Cancer 2020;11(7):1800-1807
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Yu J, Wang W, Yao W, Yang Z, Gao P, Liu M, Wang H, Chen S, Wang D, Wang W, Sun G
Journal of Cancer 2020;11(19):5568-5577
Journal of Cancer 2020;11(19):5568-5577
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Zhang YY, Luo LM, Wang YX, Zhu N, Zhao TJ, Qin L
Journal of Cancer 2020;11(14):4261-4273
Journal of Cancer 2020;11(14):4261-4273
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
Jin Y, Liu J, Liu Y, Liu Y, Guo G, Yu S, An R
Frontiers in pharmacology 2020;11:808
Frontiers in pharmacology 2020;11:808
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway.
Deng G, Zeng F, Su J, Zhao S, Hu R, Zhu W, Hu S, Chen X, Yin M
Theranostics 2020;10(25):11428-11443
Theranostics 2020;10(25):11428-11443
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.
Xu H, Wang H, Zhao W, Fu S, Li Y, Ni W, Xin Y, Li W, Yang C, Bai Y, Zhan M, Lu L
Theranostics 2020;10(13):5671-5686
Theranostics 2020;10(13):5671-5686
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer.
Huang T, Fan Q, Wang Y, Cui Y, Wang Z, Yang L, Sun X, Wang Y
Frontiers in oncology 2020;10:19
Frontiers in oncology 2020;10:19
Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway.
Gao X, Qiao X, Xing X, Huang J, Qian J, Wang Y, Zhang Y, Zhang X, Li M, Cui J, Yang Y
Frontiers in oncology 2020;10:1563
Frontiers in oncology 2020;10:1563
Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer.
Zhu W, Liu C, Lu T, Zhang Y, Zhang S, Chen Q, Deng N
Frontiers in oncology 2020;10:1451
Frontiers in oncology 2020;10:1451
Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions.
Wei R, Chen L, Qin D, Guo Q, Zhu S, Li P, Min L, Zhang S
Frontiers in oncology 2020;10:1372
Frontiers in oncology 2020;10:1372
Ziyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells.
Liao W, Fan L, Zheng Z, Liu H, Deng H, Li M, Liu F, Yang A
Anti-cancer drugs 2020 Sep;31(8):819-827
Anti-cancer drugs 2020 Sep;31(8):819-827
Dysfunction of pulmonary epithelial tight junction induced by silicon dioxide nanoparticles via the ROS/ERK pathway and protein degradation.
Liu Y, Wei H, Tang J, Yuan J, Wu M, Yao C, Hosoi K, Yu S, Zhao X, Han Y, Chen G
Chemosphere 2020 Sep;255:126954
Chemosphere 2020 Sep;255:126954
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Li J, Liu J, Yue W, Xu K, Cai W, Cui F, Li Z, Wang W, He J
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Activation of calcium‑sensing receptor‑mediated autophagy in high glucose‑induced cardiac fibrosis in vitro.
Yuan H, Xu J, Zhu Y, Li L, Wang Q, Yu Y, Zhou B, Liu Y, Xu X, Wang Z
Molecular medicine reports 2020 Sep;22(3):2021-2031
Molecular medicine reports 2020 Sep;22(3):2021-2031
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Song X, Yang W, Wu C, Han Y, Lu Y
Oncology letters 2020 Sep;20(3):2897-2905
Oncology letters 2020 Sep;20(3):2897-2905
Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells.
Tian C, Zhang B, Ge C
Oncology letters 2020 Sep;20(3):2677-2688
Oncology letters 2020 Sep;20(3):2677-2688
ERK/AKT Inactivation and Apoptosis Induction Associate With Quetiapine-inhibited Cell Survival and Invasion in Hepatocellular Carcinoma Cells.
Lee YJ, Chung JG, Tan ZL, Hsu FT, Liu YC, Lin SS
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2407-2417
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2407-2417
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, Ma F, Gao Q, Chang R, Lee HH, Zhao S, Su J, Li H, Peng J, Chen H, Yin M, Peng C, Yang N, Wang J, Liu J, Liu H, Han L, Chen X
Genome medicine 2020 Sep 28;12(1):83
Genome medicine 2020 Sep 28;12(1):83
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Zheng D, Wu Z, Han J, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 Sep 25;329:109202
Chemico-biological interactions 2020 Sep 25;329:109202
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Elastophagocytosis and interstitial granulomatous infiltrate are more common in extragenital vs genital lichen sclerosus.
Fancher K, Gardner JM, Shalin SC
Journal of cutaneous pathology 2020 Oct;47(10):903-912
Journal of cutaneous pathology 2020 Oct;47(10):903-912
Lactate induced up-regulation of KLHDC8A (Kelch domain-containing 8A) contributes to the proliferation, migration and apoptosis of human glioma cells.
Zhu X, Chen T, Yang H, Lv K
Journal of cellular and molecular medicine 2020 Oct;24(20):11691-11702
Journal of cellular and molecular medicine 2020 Oct;24(20):11691-11702
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis.
Zhang JX, Qin MB, Ye Z, Peng P, Li SM, Song Q, Lin L, Liu SQ, Xie LH, Zhu Y, Huang JA
Oncology reports 2020 Nov;44(5):2174-2184
Oncology reports 2020 Nov;44(5):2174-2184
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p.
Zhang G, Yang W, Li D, Li X, Huang J, Huang R, Luo J
Molecular medicine reports 2020 Nov;22(5):3635-3644
Molecular medicine reports 2020 Nov;22(5):3635-3644
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Wu J, Guo L, Qiu X, Ren Y, Li F, Cui W, Song S
British journal of cancer 2020 Nov;123(11):1673-1685
British journal of cancer 2020 Nov;123(11):1673-1685
Insulin-like growth factor-binding protein 3 inhibits angiotensin II-induced aortic smooth muscle cell phenotypic switch and matrix metalloproteinase expression.
Chen S, Chen H, Zhong Y, Ge Y, Li C, Qiao Z, Zhu J
Experimental physiology 2020 Nov;105(11):1827-1839
Experimental physiology 2020 Nov;105(11):1827-1839
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Guo Y, Cao F, Hu S, Liu S, Sun H, Li A, Li F
Discovery medicine 2020 Nov-Dec;30(161):145-153
Discovery medicine 2020 Nov-Dec;30(161):145-153
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Ying X, Xie Q, Li S, Yu X, Zhou K, Yue J, Chen X, Tu W, Yang G, Jiang S
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956
IUBMB life 2020 May;72(5):942-956
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Wnt/β‑catenin signaling modulates piperine‑mediated antitumor effects on human osteosarcoma cells.
Qi YB, Yang W, Si M, Nie L
Molecular medicine reports 2020 May;21(5):2202-2208
Molecular medicine reports 2020 May;21(5):2202-2208
MicroRNA-203 restrains epithelial-mesenchymal transition, invasion and migration of papillary thyroid cancer by downregulating AKT3.
You A, Fu L, Li Y, Li X, You B
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1105-1121
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1105-1121
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
Sun YS, Thakur K, Hu F, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
Li S, Hou X, Wu C, Han L, Li Q, Wang J, Luo S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
Wang N, Lu K, Qu H, Wang H, Chen Y, Shan T, Ge X, Wei Y, Zhou P, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway.
Chen K, Jiao J, Xue J, Chen T, Hou Y, Jiang Y, Qian L, Wang Y, Ma Z, Liang Z, Sun B, Ren Q
Oncology reports 2020 Mar;43(3):886-896
Oncology reports 2020 Mar;43(3):886-896
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Zhao CC, Yu WW, Qi YJ, Xu LF, Wang ZR, Qiang YW, Ma F, Ma XL
Anti-cancer drugs 2020 Mar;31(3):223-230
Anti-cancer drugs 2020 Mar;31(3):223-230
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, Jiang Y, Li C, Wang M, Yang F, Li G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
Qu Q, Pang Y, Zhang C, Liu L, Bi Y
Stem cell research & therapy 2020 Mar 23;11(1):133
Stem cell research & therapy 2020 Mar 23;11(1):133
HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.
Wang X, Feng Q, Yu H, Zhou X, Shan C, Zhang Q, Liu S
Life sciences 2020 Mar 15;245:117354
Life sciences 2020 Mar 15;245:117354
Long non-coding RNA lnc-DC in dendritic cells regulates trophoblast invasion via p-STAT3-mediated TIMP/MMP expression.
Zhang W, Yang M, Yu L, Hu Y, Deng Y, Liu Y, Xiao S, Ding Y
American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Jun;83(6):e13239
American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Jun;83(6):e13239
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, Zhan Z, Sferra TJ, Sankararaman S, Lin J
The Journal of international medical research 2020 Jun;48(6):300060520925598
The Journal of international medical research 2020 Jun;48(6):300060520925598
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
Wu H, Wei M, Jiang X, Tan J, Xu W, Fan X, Zhang R, Ding C, Zhao F, Shao X, Zhang Z, Shi R, Zhang W, Wu G
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway.
Liu X, Shen S, Zhu L, Su R, Zheng J, Ruan X, Shao L, Wang D, Yang C, Liu Y
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
Journal of experimental & clinical cancer research : CR 2020 Jun 29;39(1):121
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
KLF5 inhibits STAT3 activity and tumor metastasis in prostate cancer by suppressing IGF1 transcription cooperatively with HDAC1.
Ma JB, Bai JY, Zhang HB, Jia J, Shi Q, Yang C, Wang X, He D, Guo P
Cell death & disease 2020 Jun 16;11(6):466
Cell death & disease 2020 Jun 16;11(6):466
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity.
Wang H, Cai J, Du S, Wei W, Shen X
Experimental cell research 2020 Jun 1;391(1):111984
Experimental cell research 2020 Jun 1;391(1):111984
Activities of matrix metalloproteinase-2, matrix metalloproteinase-9, and serine proteases in samples of the colorectal mucosa of Miniature Dachshunds with inflammatory colorectal polyps.
Nagata N, Ohta H, Yamada A, Teoh YB, Ichii O, Morishita K, Sasaki N, Takiguchi M
American journal of veterinary research 2020 Jul;81(7):572-580
American journal of veterinary research 2020 Jul;81(7):572-580
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
Su Z, Yang B, Zeng Z, Zhu S, Wang C, Lei S, Jiang Y, Lin L
Oncology letters 2020 Jul;20(1):99-112
Oncology letters 2020 Jul;20(1):99-112
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Wang J, Wang C, Li Q, Guo C, Sun W, Zhao D, Jiang S, Hao L, Tian Y, Liu S, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, Yang J, Yao Y, Yan J, Zhao L, Li H, Yang L
Cell death & disease 2020 Jul 24;11(7):576
Cell death & disease 2020 Jul 24;11(7):576
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.
Zhang Y, Cong X, Li Z, Xue Y
International immunopharmacology 2020 Jan;78:105937
International immunopharmacology 2020 Jan;78:105937
8‑Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway.
Hu SM, Yao XH, Hao YH, Pan AH, Zhou XW
International journal of oncology 2020 Jan;56(1):390-397
International journal of oncology 2020 Jan;56(1):390-397
MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.
Fan B, Jin Y, Zhang H, Zhao R, Sun M, Sun M, Yuan X, Wang W, Wang X, Chen Z, Liu W, Yu N, Wang Q, Liu T, Li X
International journal of oncology 2020 Jan;56(1):178-192
International journal of oncology 2020 Jan;56(1):178-192
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356
Redox biology 2020 Jan;28:101356
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway.
Cheng B, Rong A, Zhou Q, Li W
Journal of experimental & clinical cancer research : CR 2020 Jan 3;39(1):5
Journal of experimental & clinical cancer research : CR 2020 Jan 3;39(1):5
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
Liu X, Zhao J, Luan X, Li S, Zhai J, Liu J, Du Y
Placenta 2020 Jan 1;89:33-41
Placenta 2020 Jan 1;89:33-41
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Zhao X, Zhang C, Wei X, Shi L, Dai S, Jia J, Wei S, Wang Y, Wang Y, Cheng J, Zhao L
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Wang Y, Liu G, Sun S, Qin J
Genes & genomics 2020 Feb;42(2):217-224
Genes & genomics 2020 Feb;42(2):217-224
Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p.
Jiang G, Dong H, Dong Y, Yang X
Molecular medicine reports 2020 Feb;21(2):768-776
Molecular medicine reports 2020 Feb;21(2):768-776
Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway.
Zhang Y, Weng Q, Han J, Chen J
Molecular medicine reports 2020 Feb;21(2):675-684
Molecular medicine reports 2020 Feb;21(2):675-684
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
Xue J, Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Li H, Jiang W, Li G, Zhao W, Zhang X
Cancer letters 2020 Feb 28;471:12-26
Cancer letters 2020 Feb 28;471:12-26
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
Gao L, Nie X, Zheng M, Li X, Guo Q, Liu J, Liu Q, Hao Y, Lin B
Life sciences 2020 Feb 15;243:116910
Life sciences 2020 Feb 15;243:116910
Discovery of 9O-Substituted Palmatine Derivatives as a New Class of anti-COL1A1 Agents via Repressing TGF-β1/Smads and JAK1/STAT3 Pathways.
Fan T, Ge M, Guo Z, He H, Zhang N, Li Y, Song D
Molecules (Basel, Switzerland) 2020 Feb 11;25(4)
Molecules (Basel, Switzerland) 2020 Feb 11;25(4)
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
Xiao Y, Liu S, Li J, Dai W, Tang W, Xiang L, Zhang W, Lin J, Wang J, Wu X, Liu G, Liu Y, Chen Y, Zhu H, Wang Y, Lin Z, Yang Q, Chen T, Sun Y, Li A, Xiong J, Wang J
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
Zhang W, Han L, Xing P, Liu B, Sun Z, Zhou W, Dong J
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
The kinesin motor protein KIF4A as a potential therapeutic target in renal cell carcinoma.
Liu G, Lu Y, Li L, Jiang T, Chu S, Hou P, Bai J, Chen M
Investigational new drugs 2020 Dec;38(6):1730-1742
Investigational new drugs 2020 Dec;38(6):1730-1742
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
MiR-126-5p promotes contractile switching of aortic smooth muscle cells by targeting VEPH1 and alleviates Ang II-induced abdominal aortic aneurysm in mice.
Shi X, Ma W, Pan Y, Li Y, Wang H, Pan S, Tian Y, Xu C, Li L
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1564-1574
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1564-1574
Circular RNA circRIMS1 Acts as a Sponge of miR-433-3p to Promote Bladder Cancer Progression by Regulating CCAR1 Expression.
Wang F, Fan M, Cai Y, Zhou X, Tai S, Yu Y, Wu H, Zhang Y, Liu J, Huang S, He N, Hu Z, Jin X
Molecular therapy. Nucleic acids 2020 Dec 4;22:815-831
Molecular therapy. Nucleic acids 2020 Dec 4;22:815-831
Transplanting Rac1-silenced bone marrow mesenchymal stem cells promote neurological function recovery in TBI mice.
Huang D, Siaw-Debrah F, Wang H, Ye S, Wang K, Wu K, Zhang Y, Wang H, Yao C, Chen J, Yan L, Zhang CL, Zhuge Q, Yang J
Aging 2020 Dec 19;13(2):2822-2850
Aging 2020 Dec 19;13(2):2822-2850
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Yu W, Xiao L, Que Y, Li S, Chen L, Hu P, Xiong R, Seta F, Chen H, Tong X
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, Feng J, Ye Q, Li J, Li G, Fan Z
International journal of molecular medicine 2020 Aug;46(2):633-640
International journal of molecular medicine 2020 Aug;46(2):633-640
PRCC-TFE3 regulates migration and invasion of translocation renal cell carcinomas via activation of Drp1-dependent mitochondrial fission.
Wang B, Gan W, Han X, Li D
Cell biology international 2020 Aug;44(8):1727-1733
Cell biology international 2020 Aug;44(8):1727-1733
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
MicroRNA-505-3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression.
Cheng Z, Wang B, Zhang C
Oncology letters 2020 Aug;20(2):1663-1670
Oncology letters 2020 Aug;20(2):1663-1670
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Wu M, Tan X, Liu P, Yang Y, Huang Y, Liu X, Meng X, Yu B, Wu Y, Jin H
Life sciences 2020 Aug 15;255:117857
Life sciences 2020 Aug 15;255:117857
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Liu W, Li Y, Feng S, Guan Y, Cao Y
Journal of biochemistry 2020 Aug 1;168(2):159-170
Journal of biochemistry 2020 Aug 1;168(2):159-170
MicroRNA-1298-5p inhibits cell proliferation and the invasiveness of bladder cancer cells via down-regulation of connexin 43.
Li G, Sun L, Mu Z, Liu S, Qu H, Xie Q, Hu B
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):227-237
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):227-237
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
IκB kinase α: an independent prognostic factor that promotes the migration and invasion of oral squamous cell carcinoma.
Lv S, Wang F, Wang K, Fan Y, Xu J, Zheng J, Zeng Y
The British journal of oral & maxillofacial surgery 2020 Apr;58(3):296-303
The British journal of oral & maxillofacial surgery 2020 Apr;58(3):296-303
Wnt5a is involved in LOX-1 and TLR4 induced host inflammatory response in peri-implantitis.
Zhang Q, Liu J, Ma L, Bai N, Xu H
Journal of periodontal research 2020 Apr;55(2):199-208
Journal of periodontal research 2020 Apr;55(2):199-208
Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy.
Zhang M, Wang X, Liu M, Liu D, Pan J, Tian J, Jin T, Xu Y, An F
Journal of cellular and molecular medicine 2020 Apr;24(8):4612-4623
Journal of cellular and molecular medicine 2020 Apr;24(8):4612-4623
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine.
Hsu FT, Chiang IT, Wang WS
Journal of cellular and molecular medicine 2020 Apr;24(7):3982-4000
Journal of cellular and molecular medicine 2020 Apr;24(7):3982-4000
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
Gong F, Chai W, Wang J, Cheng H, Shi Y, Cui L, Jia G
Acta histochemica 2020 Apr;122(3):151527
Acta histochemica 2020 Apr;122(3):151527
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Miao Z, Ding Y, Zhao N, Chen X, Cheng H, Wang J, Liu Y, Wang F
The international journal of biochemistry & cell biology 2020 Apr;121:105696
The international journal of biochemistry & cell biology 2020 Apr;121:105696
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Tang H, Chu Y, Huang Z, Cai J, Wang Z
Carcinogenesis 2020 Apr 22;41(2):182-193
Carcinogenesis 2020 Apr 22;41(2):182-193
Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice.
Lin H, Zhou W, Huang Y, Ren M, Xu F, Wang H
Acta biochimica et biophysica Sinica 2020 Apr 20;52(4):421-429
Acta biochimica et biophysica Sinica 2020 Apr 20;52(4):421-429
Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene.
Huang G, Ma J, Zhang L
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 19;26:e920623
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Wang S, Yao Y, Li H, Zheng G, Lu S, Chen W
American journal of cancer research 2019;9(9):1957-1969
American journal of cancer research 2019;9(9):1957-1969
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Zhang S, Hu P, Liu T, Li Z, Huang Y, Liao J, Hamid MR, Wen L, Wang T, Mo C, Alini M, Grad S, Wang T, Chen D, Zhou G
Theranostics 2019;9(24):7108-7121
Theranostics 2019;9(24):7108-7121
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
Guo Q, Zhu L, Wang C, Wang S, Nie X, Liu J, Liu Q, Hao Y, Li X, Lin B
Frontiers in oncology 2019;9:954
Frontiers in oncology 2019;9:954
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, Xiao G, Li Z
Frontiers in oncology 2019;9:461
Frontiers in oncology 2019;9:461
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
Fan Y, Li N, Liu C, Dong H, Hu X
Journal of vascular research 2019;56(5):230-240
Journal of vascular research 2019;56(5):230-240
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Feng X, Yan N, Sun W, Zheng S, Jiang S, Wang J, Guo C, Hao L, Tian Y, Liu S, Sun MZ
Cell death discovery 2019;5:89
Cell death discovery 2019;5:89
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, Zuo D, Zhang W, Wu Y
Cancer biology & therapy 2019;20(4):513-523
Cancer biology & therapy 2019;20(4):513-523
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
Wang J, Zheng M, Zhu L, Deng L, Li X, Gao L, Wang C, Wang H, Liu J, Lin B
Cancer cell international 2019;19:330
Cancer cell international 2019;19:330
LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis.
Zheng Y, Zheng B, Meng X, Yan Y, He J, Liu Y
Cancer cell international 2019;19:302
Cancer cell international 2019;19:302
Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA.
Wang L, Zhao F, Xiao Z, Yao L
Cancer cell international 2019;19:281
Cancer cell international 2019;19:281
Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner.
Yu S, Zhou R, Yang T, Liu S, Cui Z, Qiao Q, Zhang J
Cancer cell international 2019;19:116
Cancer cell international 2019;19:116
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis.
Feng H, Zhao X, Guo Q, Feng Y, Ma M, Guo W, Dong X, Deng C, Li C, Song X, Han S, Cao L
International journal of biological sciences 2019;15(3):507-521
International journal of biological sciences 2019;15(3):507-521
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Xia B, Wang J
Drug design, development and therapy 2019;13:3837-3844
Drug design, development and therapy 2019;13:3837-3844
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Gu Y, Li C, Xiao L, Li J, Pei H, Xu D, Jiang Y, Zhang X, Zhang L, Li K, Zhu Z, Chen X
American journal of translational research 2019;11(9):5438-5456
American journal of translational research 2019;11(9):5438-5456
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Nie X, Liu C, Guo Q, Zheng MJ, Gao LL, Li X, Liu DW, Zhu LC, Liu JJ, Lin B
Cancer management and research 2019;11:839-855
Cancer management and research 2019;11:839-855
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
Guo L, Yang T
Cancer management and research 2019;11:10499-10508
Cancer management and research 2019;11:10499-10508
Downregulation of RAI14 inhibits the proliferation and invasion of breast cancer cells.
Gu M, Zheng W, Zhang M, Dong X, Zhao Y, Wang S, Jiang H, Liu L, Zheng X
Journal of Cancer 2019;10(25):6341-6348
Journal of Cancer 2019;10(25):6341-6348
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Suo L, Chang X, Xu N, Ji H
Frontiers in endocrinology 2019;10:370
Frontiers in endocrinology 2019;10:370
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Chen J, Li D, Luo E
International immunopharmacology 2019 Sep;74:105683
International immunopharmacology 2019 Sep;74:105683
SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.
Gu X, Jiang Y, Xue W, Song C, Wang Y, Liu Y, Cui B
Clinical and experimental pharmacology & physiology 2019 Sep;46(9):861-871
Clinical and experimental pharmacology & physiology 2019 Sep;46(9):861-871
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
Wang P, Liu X, Han G, Dai S, Ni Q, Xiao S, Huang J
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
Estradiol promotes trophoblast viability and invasion by activating SGK1.
He WH, Jin MM, Liu AP, Zhou Y, Hu XL, Zhu YM, Liu AX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109092
HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.
Zhu H, Dai W, Li J, Xiang L, Wu X, Tang W, Chen Y, Yang Q, Liu M, Xiao Y, Zhang W, Lin J, Wang J, Liu G, Sun Y, Jiang P, Li G, Li A, Liu S, Chen Y, Wang J
Journal of experimental & clinical cancer research : CR 2019 Sep 23;38(1):412
Journal of experimental & clinical cancer research : CR 2019 Sep 23;38(1):412
Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells.
Matsuzaki Y, Maruta R, Takaki K, Kotani E, Kato Y, Yoshimura R, Endo Y, Whitty C, Pernstich C, Gandhi R, Jones M, Mori H
Biomolecules 2019 Sep 20;9(10)
Biomolecules 2019 Sep 20;9(10)
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
Zhong B, Shi D, Wu F, Wang S, Hu H, Cheng C, Qing X, Huang X, Luo X, Zhang Z, Shao Z
Cell death & disease 2019 Sep 18;10(10):687
Cell death & disease 2019 Sep 18;10(10):687
MicroRNA-99a-5p alleviates atherosclerosis via regulating Homeobox A1.
Han Z, Guan Y, Liu B, Lin Y, Yan Y, Wang H, Wang H, Jing B
Life sciences 2019 Sep 1;232:116664
Life sciences 2019 Sep 1;232:116664
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
Liang JN, Zou X, Fang XH, Xu JD, Xiao Z, Zhu JN, Li H, Yang J, Zeng N, Yuan SJ, Pan R, Fu YH, Zhang M, Luo JF, Wang S, Shan ZX
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y
Oncology reports 2019 Oct;42(4):1451-1458
Oncology reports 2019 Oct;42(4):1451-1458
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Hyperoside protects against heart failure-induced liver fibrosis in rats.
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W
Acta histochemica 2019 Oct;121(7):804-811
Acta histochemica 2019 Oct;121(7):804-811
CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.
Simbulan-Rosenthal CM, Dougherty R, Vakili S, Ferraro AM, Kuo LW, Alobaidi R, Aljehane L, Gaur A, Sykora P, Glasgow E, Agarwal S, Rosenthal DS
Cancers 2019 Oct 3;11(10)
Cancers 2019 Oct 3;11(10)
Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway.
Chen M, Gilbert N, Liu H
Reproductive biology and endocrinology : RB&E 2019 Oct 27;17(1):86
Reproductive biology and endocrinology : RB&E 2019 Oct 27;17(1):86
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Liu M, Liang Y, Zhu Z, Wang J, Cheng X, Cheng J, Xu B, Li R, Liu X, Wang Y
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Wang Y, Zhou N, Li P, Wu H, Wang Q, Gao X, Wang X, Huang J
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Gao L, Zheng M, Guo Q, Nie X, Li X, Hao Y, Liu J, Zhu L, Lin B
The international journal of biochemistry & cell biology 2019 Nov;116:105617
The international journal of biochemistry & cell biology 2019 Nov;116:105617
Inhibition of perivascular mast cell activation is involved in the atheroprotective effect of rosiglitazone in apolipoprotein E-deficient mice.
Li Q, Xiao Y, Lu G, Xie D, Zhai Y, Zhang J, Li J, Gao X
Biochemical and biophysical research communications 2019 Nov 5;519(2):261-266
Biochemical and biophysical research communications 2019 Nov 5;519(2):261-266
Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery.
Jiang MS, Yin XY, Qin B, Xuan SY, Yuan XL, Yin H, Zhu C, Li X, Yang J, Du YZ, Luo LH, You J
Molecular pharmaceutics 2019 Nov 4;16(11):4530-4541
Molecular pharmaceutics 2019 Nov 4;16(11):4530-4541
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation.
Huang A, Honda Y, Li P, Tanaka T, Baba S
International journal of molecular sciences 2019 Nov 30;20(23)
International journal of molecular sciences 2019 Nov 30;20(23)
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Lee KF, Tsai MM, Tsai CY, Huang CG, Ou YH, Hsieh CC, Hsieh HL, Wang CS, Lin KH
International journal of molecular sciences 2019 Nov 13;20(22)
International journal of molecular sciences 2019 Nov 13;20(22)
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals.
Xue D, Wang H, Chen Y, Shen D, Lu J, Wang M, Zebibula A, Xu L, Wu H, Li G, Xia L
Molecular cancer 2019 Nov 1;18(1):151
Molecular cancer 2019 Nov 1;18(1):151
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Khan A, Fan K, Sun N, Yin W, Sun Y, Sun P, Jahejo AR, Li H
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury.
Chen L, Kong L, Wei X, Wang Y, Wang B, Zhang X, Sun J, Liu H
Journal of cellular and molecular medicine 2019 May;23(5):3325-3335
Journal of cellular and molecular medicine 2019 May;23(5):3325-3335
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Zhou B, Li W, Zhao G, Yu B, Ma B, Liu Z, Xie N, Fu Y, Gong Z, Dai R, Zhang X, Kong W
Journal of vascular surgery 2019 Mar;69(3):921-932.e3
Journal of vascular surgery 2019 Mar;69(3):921-932.e3
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
Wang S, Yao Y, Rao C, Zheng G, Chen W
International journal of oncology 2019 Mar;54(3):966-980
International journal of oncology 2019 Mar;54(3):966-980
miR‑16‑2‑3p inhibits cell proliferation and migration and induces apoptosis by targeting PDPK1 in maxillary primordium mesenchymal cells.
Han T, Wu N, Wang Y, Shen W, Zou J
International journal of molecular medicine 2019 Mar;43(3):1441-1451
International journal of molecular medicine 2019 Mar;43(3):1441-1451
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Zhang X, Yang X, Zhu S, Li Q, Zou N
Oncology reports 2019 Mar;41(3):1960-1970
Oncology reports 2019 Mar;41(3):1960-1970
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.
Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Bosari S, Caroli M, Ottobrini L, Vaccari T, Vaira V
EBioMedicine 2019 Mar;41:214-224
EBioMedicine 2019 Mar;41:214-224
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer.
Chen J, Yu Y, Li H, Hu Q, Chen X, He Y, Xue C, Ren F, Ren Z, Li J, Liu L, Duan Z, Cui G, Sun R
Molecular cancer 2019 Mar 2;18(1):33
Molecular cancer 2019 Mar 2;18(1):33
AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model.
Wang X, Pan J, Liu H, Zhang M, Liu D, Lu L, Tian J, Liu M, Jin T, An F
Life sciences 2019 Mar 15;221:249-258
Life sciences 2019 Mar 15;221:249-258
Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis.
Wang D, Zheng J, Liu X, Xue Y, Liu L, Ma J, He Q, Li Z, Cai H, Liu Y
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
Molecular therapy. Nucleic acids 2019 Mar 1;14:465-482
Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis.
Dai L, Hu W, Yang Z, Chen D, He B, Chen Y, Zhou L, Xie H, Wu J, Zheng S
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):736-748
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):736-748
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Wang L, Li S, Yu X, Han Y, Wu Y, Wang S, Chen X, Zhang J, Wang S
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells.
Li Y, Zhao L, Qi Y, Yang X
Molecular medicine reports 2019 Jun;19(6):4935-4945
Molecular medicine reports 2019 Jun;19(6):4935-4945
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
Guo Y, Cui W, Pei Y, Xu D
Gynecologic oncology 2019 Jun;153(3):639-650
Gynecologic oncology 2019 Jun;153(3):639-650
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Li QH, Liu Y, Chen S, Zong ZH, Du YP, Sheng XJ, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.
Gao J, Wang Y, Yang J, Zhang W, Meng K, Sun Y, Li Y, He QY
Cancers 2019 Jun 18;11(6)
Cancers 2019 Jun 18;11(6)
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway.
Xie Q, Yang Z, Huang X, Zhang Z, Li J, Ju J, Zhang H, Ma J
Journal of hematology & oncology 2019 Jun 11;12(1):60
Journal of hematology & oncology 2019 Jun 11;12(1):60
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Yao Y, Rao C, Zheng G, Wang S
Oncology reports 2019 Jul;42(1):131-141
Oncology reports 2019 Jul;42(1):131-141
Amentoflavone Induces Apoptosis and Reduces Expression of Anti-apoptotic and Metastasis-associated Proteins in Bladder Cancer.
Chiang CH, Yeh CY, Chung JG, Chiang IT, Hsu FT
Anticancer research 2019 Jul;39(7):3641-3649
Anticancer research 2019 Jul;39(7):3641-3649
Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-β1/Smad2 signaling pathway.
Chen P, Tian K, Tu W, Zhang Q, Han L, Zhou X
Toxicology and applied pharmacology 2019 Jul 1;374:1-10
Toxicology and applied pharmacology 2019 Jul 1;374:1-10
Effect of SEPT6 on the biological behavior of hepatic stellate cells and liver fibrosis in rats and its mechanism.
Fan Y, Du Z, Steib CJ, Ding Q, Lu P, Tian D, Liu M
Laboratory investigation; a journal of technical methods and pathology 2019 Jan;99(1):17-36
Laboratory investigation; a journal of technical methods and pathology 2019 Jan;99(1):17-36
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Liu SQ, Xu CY, Wu WH, Fu ZH, He SW, Qin MB, Huang JA
International journal of oncology 2019 Jan;54(1):41-52
International journal of oncology 2019 Jan;54(1):41-52
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Yu H, Fu QR, Huang ZJ, Lin JY, Chen QX, Wang Q, Shen DY
Oncology reports 2019 Jan;41(1):213-223
Oncology reports 2019 Jan;41(1):213-223
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway.
Wu W, Gao H, Li X, Peng S, Yu J, Liu N, Zhan G, Zhu Y, Wang K, Guo X
Cell cycle (Georgetown, Tex.) 2019 Jan;18(1):46-59
Cell cycle (Georgetown, Tex.) 2019 Jan;18(1):46-59
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Zhang T, Li Q, Wang L, Li G
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2).
Li X, Huang L, Gao W
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 27;25:771-777
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 27;25:771-777
NCK1 promotes the angiogenesis of cervical squamous carcinoma via Rac1/PAK1/MMP2 signal pathway.
Xia P, Huang M, Zhang Y, Xiong X, Yan M, Xiong X, Yu W, Song E
Gynecologic oncology 2019 Feb;152(2):387-395
Gynecologic oncology 2019 Feb;152(2):387-395
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Li Y, Chen Y, Qiu C, Ma X, Lei K, Cai G, Liang X, Liu J
Journal of cellular biochemistry 2019 Feb;120(2):1560-1576
Journal of cellular biochemistry 2019 Feb;120(2):1560-1576
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Zhang P, Chen FZ, Jia QB, Hu DF
IUBMB life 2019 Dec;71(12):1857-1875
IUBMB life 2019 Dec;71(12):1857-1875
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Dai L, Zhou J, Li T, Qian Y, Jin L, Zhu C, Li S
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Journal of cellular physiology 2019 Dec;234(12):22463-22476
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Guan X, Zong ZH, Liu Y, Chen S, Wang LL, Zhao Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Upregulation of fascin-1 is involved in HIF-1α-dependent invasion and migration of hypopharyngeal squamous cell carcinoma.
Bu M, Liu X, Liu X, Xu W
International journal of oncology 2019 Aug;55(2):488-498
International journal of oncology 2019 Aug;55(2):488-498
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway.
Wang X, Pan J, Liu D, Zhang M, Li X, Tian J, Liu M, Jin T, An F
Journal of cellular and molecular medicine 2019 Aug;23(8):5349-5359
Journal of cellular and molecular medicine 2019 Aug;23(8):5349-5359
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice.
Dimitriadis GK, Nasiri-Ansari N, Agrogiannis G, Kostakis ID, Randeva MS, Nikiteas N, Patel VH, Kaltsas G, Papavassiliou AG, Randeva HS, Kassi E
Molecular and cellular endocrinology 2019 Aug 20;494:110487
Molecular and cellular endocrinology 2019 Aug 20;494:110487
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
Zhang F, Lu S, He J, Jin H, Wang F, Wu L, Shao J, Chen A, Zheng S
Theranostics 2018;8(3):610-626
Theranostics 2018;8(3):610-626
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Peng X, Kang Q, Wan R, Wang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis.
Gao Y, Yu H, Liu Y, Liu X, Zheng J, Ma J, Gong W, Chen J, Zhao L, Tian Y, Xue Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):131-147
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):131-147
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Zhu JF, Liu Y, Huang H, Shan L, Han ZG, Liu JY, Li YL, Dong X, Zeng W
Cancer cell international 2018;18:193
Cancer cell international 2018;18:193
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart.
Liu F, Wen Y, Kang J, Wei C, Wang M, Zheng Z, Peng J
International journal of molecular medicine 2018 Sep;42(3):1436-1444
International journal of molecular medicine 2018 Sep;42(3):1436-1444
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Wang X, Xu K, Yang XY, Liu J, Zeng Q, Wang FS
Human & experimental toxicology 2018 Sep;37(9):944-952
Human & experimental toxicology 2018 Sep;37(9):944-952
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Batool S, Joseph TP, Hussain M, Vuai MS, Khinsar KH, Din SRU, Padhiar AA, Zhong M, Ning A, Zhang W, Cao J, Huang M
International journal of molecular sciences 2018 Sep 30;19(10)
International journal of molecular sciences 2018 Sep 30;19(10)
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, Song E, Song Y
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness.
Luo Y, Mohsin A, Xu C, Wang Q, Hang H, Zhuang Y, Chu J, Guo M
Cytotechnology 2018 Oct;70(5):1409-1422
Cytotechnology 2018 Oct;70(5):1409-1422
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Zeng K, Chen X, Hu X, Liu X, Xu T, Sun H, Pan Y, He B, Wang S
Oncogene 2018 Oct;37(41):5534-5551
Oncogene 2018 Oct;37(41):5534-5551
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Zhang XS, Wang KY, Gao JQ, Li RJ, Guan QB, Song L
Oncology letters 2018 Oct;16(4):4291-4296
Oncology letters 2018 Oct;16(4):4291-4296
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
He XX, Shi LL, Qiu MJ, Li QT, Wang MM, Xiong ZF, Yang SL
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
Duan Y, Dong Y, Dang R, Hu Z, Yang Y, Hu Y, Cheng J
Cell biology international 2018 Nov;42(11):1564-1574
Cell biology international 2018 Nov;42(11):1564-1574
In Vitro Study of Colon Cancer Cell Migration Using E-Jet 3D Printed Cell Culture Platforms.
Zhong J, Zhang Y, Chen J, Huang R, Yang Y, Chen H, Huang Y, Tan W, Tan Z
Macromolecular bioscience 2018 Nov;18(11):e1800205
Macromolecular bioscience 2018 Nov;18(11):e1800205
The relationship between lncRNA PCGEM1 and STAT3 during the occurrence and development of endometrial carcinoma.
Li Q, Shen F, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:918-928
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:918-928
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Magnolol Induces Apoptosis and Inhibits ERK-modulated Metastatic Potential in Hepatocellular Carcinoma Cells.
Kuan LY, Chen WL, Chen JH, Hsu FT, Liu TT, Chen WT, Wang KL, Chen WC, Liu YC, Wang WS
In vivo (Athens, Greece) 2018 Nov-Dec;32(6):1361-1368
In vivo (Athens, Greece) 2018 Nov-Dec;32(6):1361-1368
Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling.
Liu SC, Hsu T, Chang YS, Chung AK, Jiang SS, OuYang CN, Yuh CH, Hsueh C, Liu YP, Tsang NM
Nature communications 2018 Nov 30;9(1):5105
Nature communications 2018 Nov 30;9(1):5105
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Yuan Q, Chen X, Han Y, Lei T, Wu Q, Yu X, Wang L, Fan Z, Wang S
International journal of cancer 2018 Nov 1;143(9):2319-2330
International journal of cancer 2018 Nov 1;143(9):2319-2330
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Liu J, Shuang Y, Li C, Zhou X, Huang Y, Zhang L
Clinical and experimental pharmacology & physiology 2018 May;45(5):461-466
Clinical and experimental pharmacology & physiology 2018 May;45(5):461-466
The Novel miRNA N-72 Regulates EGF-Induced Migration of Human Amnion Mesenchymal Stem Cells by Targeting MMP2.
Li Y, Zhang D, Chen M, Wang R, Zhang T, Zhao F, Lin X, Pang X
International journal of molecular sciences 2018 May 4;19(5)
International journal of molecular sciences 2018 May 4;19(5)
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
Wang L, Zhao Y, Wu Q, Guan Y, Wu X
Molecular medicine reports 2018 Mar;17(3):4299-4306
Molecular medicine reports 2018 Mar;17(3):4299-4306
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Yu L, Wang S, Lin X, Lu Y, Gu P
Molecular medicine reports 2018 Mar;17(3):3972-3978
Molecular medicine reports 2018 Mar;17(3):3972-3978
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Liu S, Liu B
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Guo J, Cai H, Liu X, Zheng J, Liu Y, Gong W, Chen J, Xi Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Wang AL, Li Y, Zhao Q, Fan LQ
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular medicine reports 2018 Jun;17(6):7721-7729
Ginkgetin ameliorates experimental atherosclerosis in rats.
Lian N, Tong J, Li W, Wu J, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:510-516
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:510-516
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Tian Y, He J, Liu N, Huang D, Liu Z, Yang Y, Chen J, Zhao B, Zhao S, Liang B
RSC advances 2018 Jun 13;8(39):21759-21767
RSC advances 2018 Jun 13;8(39):21759-21767
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Ci Y, Zhang Y, Liu Y, Lu S, Cao J, Li H, Zhang J, Huang Z, Zhu X, Gao J, Han M
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice.
Nasiri-Ansari Ν, Dimitriadis GK, Agrogiannis G, Perrea D, Kostakis ID, Kaltsas G, Papavassiliou AG, Randeva HS, Kassi E
Cardiovascular diabetology 2018 Jul 26;17(1):106
Cardiovascular diabetology 2018 Jul 26;17(1):106
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Zhang J, Liu L, Wang J, Ren B, Zhang L, Li W
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, Wei X, Chen C, Liu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Liu W, Liu X, Wang L, Zhu B, Zhang C, Jia W, Zhu H, Liu X, Zhong M, Xie D, Liu Y, Li S, Shi J, Lin J, Xia X, Jiang X, Ren C
Oncology reports 2018 Jan;39(1):45-52
Oncology reports 2018 Jan;39(1):45-52
Anticancer Efficacy of Targeted Shikonin Liposomes Modified with RGD in Breast Cancer Cells.
Wen X, Li J, Cai D, Yue L, Wang Q, Zhou L, Fan L, Sun J, Wu Y
Molecules (Basel, Switzerland) 2018 Jan 29;23(2)
Molecules (Basel, Switzerland) 2018 Jan 29;23(2)
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH
Scientific reports 2018 Jan 12;8(1):624
Scientific reports 2018 Jan 12;8(1):624
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.
Chen S, Wang LL, Sun KX, Xiu YL, Zong ZH, Chen X, Zhao Y
Molecular carcinogenesis 2018 Feb;57(2):225-234
Molecular carcinogenesis 2018 Feb;57(2):225-234
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, Qi W, Yang H
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Interference of Notch 1 inhibits the proliferation and invasion of breast cancer cells: Involvement of the β‑catenin signaling pathway.
Lai XX, Li G, Lin B, Yang H
Molecular medicine reports 2018 Feb;17(2):2472-2478
Molecular medicine reports 2018 Feb;17(2):2472-2478
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Guan X, Chen S, Liu Y, Wang LL, Zhao Y, Zong ZH
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Zhang L, Chen C, Duanmu J, Wu Y, Tao J, Yang A, Yin X, Xiong B, Gu J, Li C, Liu Z
International immunopharmacology 2018 Dec;65:429-437
International immunopharmacology 2018 Dec;65:429-437
Identification of COL1A1 as an invasion‑related gene in malignant astrocytoma.
Sun S, Wang Y, Wu Y, Gao Y, Li Q, Abdulrahman AA, Liu XF, Ji GQ, Gao J, Li L, Wan FP, Li YQ, Gao DS
International journal of oncology 2018 Dec;53(6):2542-2554
International journal of oncology 2018 Dec;53(6):2542-2554
Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Zhang X, Liu S, Weng X, Wu T, Yu L, Xu Y, Guo J
Journal of molecular and cellular cardiology 2018 Dec;125:6-17
Journal of molecular and cellular cardiology 2018 Dec;125:6-17
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Chen E, Yang F, He H, Li Q, Zhang W, Xing J, Zhu Z, Jiang J, Wang H, Zhao X, Liu R, Lei L, Dong J, Pei Y, Yang Y, Pan J, Zhang P, Liu S, Du L, Zeng Y, Yang J
Molecular cancer 2018 Dec 20;17(1):176
Molecular cancer 2018 Dec 20;17(1):176
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Tian YS, Chen KC, Zulkefli ND, Maner RS, Hsieh CL
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Fine Particulate Matter (PM(2.5)) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
Chen Z, Ji N, Wang Z, Wu C, Sun Z, Li Y, Hu F, Wang Z, Huang M, Zhang M
Journal of biomedical nanotechnology 2018 Dec 1;14(12):2172-2184
Journal of biomedical nanotechnology 2018 Dec 1;14(12):2172-2184
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Guo Y, Peng Y, Gao D, Zhang M, Yang W, Linghu E, Herman JG, Fuks F, Dong G, Guo M
Clinical epigenetics 2017;9:116
Clinical epigenetics 2017;9:116
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Li Y, Poppoe F, Chen J, Yu L, Deng F, Luo Q, Xu Y, Cai Y, Shen J
Frontiers in immunology 2017;8:137
Frontiers in immunology 2017;8:137
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Shen Y, Guo D, Weng L, Wang S, Ma Z, Yang Y, Wang P, Wang J, Cai Z
Oncoimmunology 2017;6(12):e1362527
Oncoimmunology 2017;6(12):e1362527
Significance of Vasculogenic Mimicry Formation in Gastric Carcinoma.
Lv J, Sun B, Sun H, Zhang Y, Sun J, Zhao X, Gu Q, Dong X, Che N
Oncology research and treatment 2017;40(1-2):35-41
Oncology research and treatment 2017;40(1-2):35-41
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Cai Y, Zhang M, Qiu X, Wang B, Fu Y, Zeng J, Bai J, Yang G
Disease markers 2017;2017:8276939
Disease markers 2017;2017:8276939
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells.
Liu Y, Tang ZG, Yang JQ, Zhou Y, Meng LH, Wang H, Li CL
OncoTargets and therapy 2017;10:4023-4028
OncoTargets and therapy 2017;10:4023-4028
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Wang Y, Wang C, Chen C, Wu F, Shen P, Zhang P, He G, Li X
Oncotarget 2017 Sep 19;8(41):70156-70171
Oncotarget 2017 Sep 19;8(41):70156-70171
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Wu W, Chen J, Wu J, Lin J, Yang S, Yu H
Oncology reports 2017 Oct;38(4):2480-2488
Oncology reports 2017 Oct;38(4):2480-2488
Mda‑7/IL‑24 induces the differentiation of B cell lymphoma via activation of the P38 mitogen activated protein kinase signaling pathway.
Ma M, Yang X, Zhao L, Liu L, Zhang C, Wang X, Shan B
Molecular medicine reports 2017 Oct;16(4):5633-5642
Molecular medicine reports 2017 Oct;16(4):5633-5642
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Liu Y, Zong ZH, Guan X, Wang LL, Zhao Y
Gene 2017 Oct 30;633:42-47
Gene 2017 Oct 30;633:42-47
BMAL1 facilitates trophoblast migration and invasion via SP1-DNMT1/DAB2IP pathway in recurrent spontaneous abortion.
Li S, Zhai J, Liu J, Hong Y, Zhao W, Zhao A, Sun K, Du Y, Chen ZJ
Oncotarget 2017 Oct 27;8(52):89451-89464
Oncotarget 2017 Oct 27;8(52):89451-89464
Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells.
Wang J, Wu Y, Guo J, Fei X, Yu L, Ma S
Oncotarget 2017 Oct 10;8(47):81880-81891
Oncotarget 2017 Oct 10;8(47):81880-81891
LOX-1 is involved in IL-1β production and extracellular matrix breakdown in dental peri-implantitis.
Che C, Liu J, Ma L, Xu H, Bai N, Zhang Q
International immunopharmacology 2017 Nov;52:127-135
International immunopharmacology 2017 Nov;52:127-135
PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds.
Zhang J, Yang X, Wang H, Zhao B, Wu X, Su L, Xie S, Wang Y, Li J, Liu J, Liu M, Han F, He T, Zhang W, Tao K, Hu D
International journal of molecular medicine 2017 Nov;40(5):1335-1346
International journal of molecular medicine 2017 Nov;40(5):1335-1346
Combination of sonodynamic with temozolomide inhibits C6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing NHE-1 expression.
Chen L, Cong D, Li Y, Wang D, Li Q, Hu S
Ultrasonics sonochemistry 2017 Nov;39:654-661
Ultrasonics sonochemistry 2017 Nov;39:654-661
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Wang LL, Sun KX, Wu DD, Xiu YL, Chen X, Chen S, Zong ZH, Sang XB, Liu Y, Zhao Y
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Li H, Qiu Z, Li F, Wang C
Oncology letters 2017 Nov;14(5):5865-5870
Oncology letters 2017 Nov;14(5):5865-5870
Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation.
Qiao L, Zheng J, Jin X, Wei G, Wang G, Sun X, Li X
Oncology letters 2017 Nov;14(5):5831-5838
Oncology letters 2017 Nov;14(5):5831-5838
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
Pan J, Xu Y, Song H, Zhou X, Yao Z, Ji G
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice.
Luo H, Li Z, Ge H, Mei D, Zhao L, Jiang L, Geng C, Li Q, Yao X, Cao J
Chemico-biological interactions 2017 Nov 1;277:1-7
Chemico-biological interactions 2017 Nov 1;277:1-7
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Zhang X, Fu L, Xue D, Zhang X, Hao F, Xie L, He J, Gai J, Liu Y, Xu H, Li Q, Wang E
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Zhu J, Zhang Y, Yang X, Jin L
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2.
Wang Y, Du J, Niu X, Fu N, Wang R, Zhang Y, Zhao S, Sun D, Nan Y
Cell death & disease 2017 May 18;8(5):e2792
Cell death & disease 2017 May 18;8(5):e2792
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Yang W, Yang S, Zhang M, Gao D, He T, Guo M
Genes & cancer 2017 Mar;8(3-4):528-535
Genes & cancer 2017 Mar;8(3-4):528-535
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
Lin ZK, Liu J, Jiang GQ, Tan G, Gong P, Luo HF, Li HM, Du J, Ning Z, Xin Y, Wang ZY
Oncology reports 2017 Mar;37(3):1611-1618
Oncology reports 2017 Mar;37(3):1611-1618
MKL1 links epigenetic activation of MMP2 to ovarian cancer cell migration and invasion.
Xu W, Xu H, Fang M, Wu X, Xu Y
Biochemical and biophysical research communications 2017 Jun 3;487(3):500-508
Biochemical and biophysical research communications 2017 Jun 3;487(3):500-508
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
Xie R, Wang J, Liu X, Wu L, Zhang H, Tang W, Li Y, Xiang L, Peng Y, Huang X, Bai Y, Liu G, Li A, Wang Y, Chen Y, Ren Y, Li G, Gong W, Liu S, Wang J
Scientific reports 2017 Jun 16;7(1):3709
Scientific reports 2017 Jun 16;7(1):3709
Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis.
Li Y, Wu Z, Yuan J, Sun L, Lin L, Huang N, Bin J, Liao Y, Liao W
Cancer letters 2017 Jun 1;395:31-44
Cancer letters 2017 Jun 1;395:31-44
MicroRNA-203 inhibits proliferation and invasion, and promotes apoptosis of osteosarcoma cells by targeting Runt-related transcription factor 2.
Lin W, Zhu X, Yang S, Chen X, Wang L, Huang Z, Ding Y, Huang L, Lv C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:1075-1084
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:1075-1084
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
Liu Y, Wang C, Shan X, Wu J, Liu H, Liu H, Zhang J, Xu W, Sha Z, He J, Fan J
Oncology letters 2017 Jul;14(1):525-532
Oncology letters 2017 Jul;14(1):525-532
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Xu B, Ye MH, Lv SG, Wang QX, Wu MJ, Xiao B, Kang CS, Zhu XG
Oncotarget 2017 Jul 4;8(27):43953-43966
Oncotarget 2017 Jul 4;8(27):43953-43966
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Su WC, Lin YF, Yu XP, Wang YX, Lin XD, Su QZ, Shen DY, Chen QX
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Wang Y, Wu N, Pang B, Tong D, Sun D, Sun H, Zhang C, Sun W, Meng X, Bai J, Chen F, Geng J, Fu S, Jin Y
Oncotarget 2017 Jul 18;8(29):47931-47942
Oncotarget 2017 Jul 18;8(29):47931-47942
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.
Xiang J, Fu X, Ran W, Wang Z
Oncogenesis 2017 Jan 9;6(1):e284
Oncogenesis 2017 Jan 9;6(1):e284
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J
British journal of cancer 2017 Feb 28;116(5):626-633
British journal of cancer 2017 Feb 28;116(5):626-633
Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy.
Kumar S, Nakashizuka H, Jones A, Lambert A, Zhao X, Shen M, Parker M, Wang S, Berriochoa Z, Fnu A, VanBeuge S, Chévez-Barrios P, Tso M, Rainier J, Fu Y
The American journal of pathology 2017 Dec;187(12):2841-2857
The American journal of pathology 2017 Dec;187(12):2841-2857
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, Cao R, Tian W
Molecular medicine reports 2017 Dec;16(6):8729-8734
Molecular medicine reports 2017 Dec;16(6):8729-8734
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Wang H, Deng L, Cai M, Zhuang H, Zhu L, Hao Y, Gao J, Liu J, Li X, Lin B
Oncotarget 2017 Dec 8;8(64):108093-108107
Oncotarget 2017 Dec 8;8(64):108093-108107
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.
Zhao G, Fu Y, Cai Z, Yu F, Gong Z, Dai R, Hu Y, Zeng L, Xu Q, Kong W
Circulation research 2017 Dec 8;121(12):1331-1345
Circulation research 2017 Dec 8;121(12):1331-1345
Effects of quercetin on proliferation and migration of human glioblastoma U251 cells.
Liu Y, Tang ZG, Lin Y, Qu XG, Lv W, Wang GB, Li CL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Aug;92:33-38
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Aug;92:33-38
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Li X, Yang Z, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
International journal of molecular medicine 2017 Aug;40(2):311-318
International journal of molecular medicine 2017 Aug;40(2):311-318
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Zou Y, Qiu G, Jiang L, Cai Z, Sun W, Hu H, Lu C, Jin W, Hu G
Oncotarget 2017 Aug 29;8(35):58231-58246
Oncotarget 2017 Aug 29;8(35):58231-58246
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Role of the lncRNA ABHD11-AS(1) in the tumorigenesis and progression of epithelial ovarian cancer through targeted regulation of RhoC.
Wu DD, Chen X, Sun KX, Wang LL, Chen S, Zhao Y
Molecular cancer 2017 Aug 17;16(1):138
Molecular cancer 2017 Aug 17;16(1):138
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Dynamics of MMP‑9, MMP‑2 and TIMP‑1 in a rat model of brain injury combined with traumatic heterotopic ossification.
Shi WZ, Ju JY, Xiao HJ, Xue F, Wu J, Pan MM, Ni WF
Molecular medicine reports 2017 Apr;15(4):2129-2135
Molecular medicine reports 2017 Apr;15(4):2129-2135
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Wang Y, Chu Y, Yue B, Ma X, Zhang G, Xiang H, Liu Y, Wang T, Wu X, Chen B
Oncotarget 2017 Apr 4;8(14):23803-23816
Oncotarget 2017 Apr 4;8(14):23803-23816
The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
Wang J, Zhang Y, Wei H, Zhang X, Wu Y, Gong A, Xia Y, Wang W, Xu M
Oncotarget 2017 Apr 11;8(15):24978-24987
Oncotarget 2017 Apr 11;8(15):24978-24987
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, Xu J, Che L, Chen X, Sluijter JP, Das S, Cretoiu D, Xu B, Zhong J, Xiao J, Li X
Theranostics 2016;6(12):2068-2083
Theranostics 2016;6(12):2068-2083
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
HOX Antisense lincRNA HOXA-AS2 Promotes Tumorigenesis of Hepatocellular Carcinoma.
Wang F, Yang H, Deng Z, Su Y, Fang Q, Yin Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):287-296
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):287-296
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Huang D, Wang S, Wang A, Chen X, Zhang H
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells.
Guo S, Wang Y, Gao Y, Zhang Y, Chen M, Xu M, Hu L, Jing Y, Jing F, Li C, Wang Q, Zhu Z
Medical science monitor : international medical journal of experimental and clinical research 2016 Oct 24;22:3951-3960
Medical science monitor : international medical journal of experimental and clinical research 2016 Oct 24;22:3951-3960
Nanoparticle-mediated arresten gene inhibits neointimal formation of vein grafts: an experimental research.
Wang RF, Meng QY
Journal of thoracic disease 2016 Nov;8(11):3081-3086
Journal of thoracic disease 2016 Nov;8(11):3081-3086
Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling.
Cao B, Yang W, Jin Y, Zhang M, He T, Zhan Q, Herman JG, Zhong G, Guo M
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Nov;11(11):1912-1926
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Nov;11(11):1912-1926
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
Hu K, Tian Y, Du Y, Huang L, Chen J, Li N, Liu W, Liang Z, Zhao L
International journal of oncology 2016 May;48(5):2166-74
International journal of oncology 2016 May;48(5):2166-74
miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.
Zhou YW, Zhang H, Duan CJ, Gao Y, Cheng YD, He D, Li R, Zhang CF
Oncotarget 2016 May 24;7(21):30730-47
Oncotarget 2016 May 24;7(21):30730-47
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Wang J, Wu Q, Zhang LH, Zhao YX, Wu X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
Si L, Zheng L, Xu L, Yin L, Han X, Qi Y, Xu Y, Wang C, Peng J
European journal of pharmacology 2016 Mar 5;774:105-17
European journal of pharmacology 2016 Mar 5;774:105-17
Yes-Associated Protein Contributes to the Development of Human Cutaneous Squamous Cell Carcinoma via Activation of RAS.
Jia J, Li C, Luo S, Liu-Smith F, Yang J, Wang X, Wang N, Lai B, Lei T, Wang Q, Xiao S, Shao Y, Zheng Y
The Journal of investigative dermatology 2016 Jun;136(6):1267-1277
The Journal of investigative dermatology 2016 Jun;136(6):1267-1277
Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing.
Yang Q, Qi X, Dang Y, Li Y, Song X, Hao X
BMC cardiovascular disorders 2016 Jun 24;16(1):142
BMC cardiovascular disorders 2016 Jun 24;16(1):142
MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway.
Lv C, Hao Y, Tu G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9333-42
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9333-42
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
Zhao M, Fan J, Liu Y, Yu Y, Xu J, Wen Q, Zhang J, Fu S, Wang B, Xiang L, Feng J, Wu J, Yang L
International journal of oncology 2016 Feb;48(2):756-64
International journal of oncology 2016 Feb;48(2):756-64
MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.
Zeng CY, Zhan YS, Huang J, Chen YX
Molecular medicine reports 2016 Feb;13(2):1297-303
Molecular medicine reports 2016 Feb;13(2):1297-303
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Molecular cancer 2016 Feb 2;15:11
Molecular cancer 2016 Feb 2;15:11
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Yuan S, Wang L, Chen X, Fan B, Yuan Q, Zhang H, Yang D, Wang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Journal of ethnopharmacology 2016 Dec 4;193:368-376
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
Su C, Zhang B, Liu W, Zheng H, Sun L, Tong J, Wang T, Jiang X, Liang H, Xue L, Zhang Q
Oncology reports 2016 Aug;36(2):1048-54
Oncology reports 2016 Aug;36(2):1048-54
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
Zhang WG, Li CF, Liu M, Chen XF, Shuai K, Kong X, Lv L, Mei ZC
Cancer letters 2016 Aug 10;378(2):111-9
Cancer letters 2016 Aug 10;378(2):111-9
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Xia ZX, Li ZX, Zhang M, Sun LM, Zhang QF, Qiu XS
Experimental and molecular pathology 2016 Apr;100(2):353-60
Experimental and molecular pathology 2016 Apr;100(2):353-60
Elevated Expression of Matrix Metalloproteinase-9 not Matrix Metalloproteinase-2 Contributes to Progression of Extracranial Arteriovenous Malformation.
Wei T, Zhang H, Cetin N, Miller E, Moak T, Suen JY, Richter GT
Scientific reports 2016 Apr 14;6:24378
Scientific reports 2016 Apr 14;6:24378
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
Wei HK, Yang SD, Bai ZL, Zhang X, Yang DL, Ding WY
International journal of clinical and experimental medicine 2015;8(11):20198-207
International journal of clinical and experimental medicine 2015;8(11):20198-207
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, Wang S, Wei Z
Cancer biology & therapy 2015;16(7):1099-109
Cancer biology & therapy 2015;16(7):1099-109
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Su CY, Liu YP, Yang CJ, Lin YF, Chiou J, Chi LH, Lee JJ, Wu AT, Lu PJ, Huang MS, Hsiao M
PloS one 2015;10(7):e0133411
PloS one 2015;10(7):e0133411
Low-dose UVB irradiation prevents MMP2-induced skin hyperplasia by inhibiting inflammation and ROS.
Dang L, Wang Y, Xue Y, He L, Li Y, Xiong J
Oncology reports 2015 Sep;34(3):1478-86
Oncology reports 2015 Sep;34(3):1478-86
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
Chu Y, Tang H, Guo Y, Guo J, Huang B, Fang F, Cai J, Wang Z
Experimental cell research 2015 Sep 10;337(1):16-27
Experimental cell research 2015 Sep 10;337(1):16-27
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice.
Wang X, Dai W, Wang Y, Gu Q, Yang D, Zhang M
International journal of environmental research and public health 2015 Sep 1;12(9):10739-54
International journal of environmental research and public health 2015 Sep 1;12(9):10739-54
Plasma miR-185 is decreased in patients with esophageal squamous cell carcinoma and might suppress tumor migration and invasion by targeting RAGE.
Jing R, Chen W, Wang H, Ju S, Cong H, Sun B, Jin Q, Chu S, Xu L, Cui M
American journal of physiology. Gastrointestinal and liver physiology 2015 Nov 1;309(9):G719-29
American journal of physiology. Gastrointestinal and liver physiology 2015 Nov 1;309(9):G719-29
ENaC mediates human extravillous trophblast cell line (HTR8/SVneo) invasion by regulating levels of matrix metalloproteinase 2 (MMP2).
Yang Y, He G, Xu W, Liu X
Placenta 2015 May;36(5):587-93
Placenta 2015 May;36(5):587-93
miR-29c suppresses pancreatic cancer liver metastasis in an orthotopic implantation model in nude mice and affects survival in pancreatic cancer patients.
Zou Y, Li J, Chen Z, Li X, Zheng S, Yi D, Zhong A, Chen J
Carcinogenesis 2015 Jun;36(6):676-84
Carcinogenesis 2015 Jun;36(6):676-84
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
The Notch pathway mediates the angiotensin II-induced synthesis of extracellular matrix components in podocytes.
Yao M, Wang X, Wang X, Zhang T, Chi Y, Gao F
International journal of molecular medicine 2015 Jul;36(1):294-300
International journal of molecular medicine 2015 Jul;36(1):294-300
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
Qiao J, Cui SJ, Xu LL, Chen SJ, Yao J, Jiang YH, Peng G, Fang CY, Yang PY, Liu F
Oncotarget 2015 Jan 20;6(2):1171-89
Oncotarget 2015 Jan 20;6(2):1171-89
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis.
Yang X, Zhang H, Wang J, Zhang Z, Li C
Journal of periodontal research 2015 Dec;50(6):748-57
Journal of periodontal research 2015 Dec;50(6):748-57
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Hu Y, Lin X, Wang P, Xue YX, Li Z, Liu LB, Yu B, Feng TD, Liu YH
Journal of cellular physiology 2015 Aug;230(8):1713-28
Journal of cellular physiology 2015 Aug;230(8):1713-28
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
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Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
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BioMed research international 2014;2014:546353
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Molecular and cellular biochemistry 2011 Nov;357(1-2):95-106
Molecular and cellular biochemistry 2011 Nov;357(1-2):95-106
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10373-2-AP(MMP2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 10373-2-AP(MMP2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MMP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MMP2. This antibody recognizes human,mouse,rat antigen. The MMP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
