Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- PAB12382 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12382, RRID:AB_10551917
- Product name
- MMP2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MMP2.
- Antigen sequence
MGPLLVATFWPELPEK
- Storage
- Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Single blastomere removal from murine embryos is associated with activation of matrix metalloproteinases and Janus kinase/signal transducers and activators of transcription pathways of placental inflammation.
PEBP4 enhanced HCC827 cell proliferation and invasion ability and inhibited apoptosis.
Effects of SASH1 on lung cancer cell proliferation, apoptosis, and invasion in vitro.
Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve.
Sato BL, Sugawara A, Ward MA, Collier AC
Molecular human reproduction 2014 Dec;20(12):1247-57
Molecular human reproduction 2014 Dec;20(12):1247-57
PEBP4 enhanced HCC827 cell proliferation and invasion ability and inhibited apoptosis.
Yu G, Shen Z, Chen G, Teng X, Hu Y, Huang B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Feb;34(1):91-8
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Feb;34(1):91-8
Effects of SASH1 on lung cancer cell proliferation, apoptosis, and invasion in vitro.
Chen EG, Chen Y, Dong LL, Zhang JS
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012 Oct;33(5):1393-401
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012 Oct;33(5):1393-401
Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis.
Mikami S, Katsube K, Oya M, Ishida M, Kosaka T, Mizuno R, Mukai M, Okada Y
Laboratory investigation; a journal of technical methods and pathology 2011 Oct;91(10):1443-58
Laboratory investigation; a journal of technical methods and pathology 2011 Oct;91(10):1443-58
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS
Cancer research 2007 Aug 1;67(15):7238-46
Cancer research 2007 Aug 1;67(15):7238-46
Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.
Krekoski CA, Neubauer D, Graham JB, Muir D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Dec 1;22(23):10408-15
MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve.
Ferguson TA, Muir D
Molecular and cellular neurosciences 2000 Aug;16(2):157-67
Molecular and cellular neurosciences 2000 Aug;16(2):157-67
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MMP2 on recombinant proteins using MMP2 polyclonal antibody (Cat # PAB12382). MMP2 polyclonal antibody (Cat # PAB12382) is specific for MMP2 (lane 5) and does not detect recombinant mouse MMP 3 (lane 1), MMP7 (lane 2), MMP9 (Lane 3) or MMP16 (lane 4).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of MMP2 in a Western blot of recombinant MMP2 and injured rat nerve lysate using MMP2 polyclonal antibody (Cat # PAB12382).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of MMP2 in a frozen injured rat nerve tissue section using MMP2 polyclonal antibody (Cat # PAB12382, 4 ug/mL).
- Validation comment
- Immunohistochemistry (Frozen sections)
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of MMP2 in a paraffin-embedded human neurofibroma section using MMP2 polyclonal antibody (Cat # PAB12382, 4 ug/mL).
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)