Antibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations [0]
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- Product number
- 66366-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- MMP2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated MMP2 antibody (Cat. #66366-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat, mouse, pig and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B10D1
- Vial size
- 20ul, 150ul
Submitted references Glutamine Protects against Mouse Abdominal Aortic Aneurysm through Modulating VSMC Apoptosis and M1 Macrophage Activation.
PD-L1 knockdown suppresses vasculogenic mimicry of non-small cell lung cancer by modulating ZEB1-triggered EMT.
TRPM7 facilitates fibroblast-like synoviocyte proliferation, metastasis and inflammation through increasing IL-6 stability via the PKCα-HuR axis in rheumatoid arthritis.
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.
miR-200a-3p inhibits the PDGF-BB-induced proliferation of VSMCs by affecting their phenotype-associated proteins.
A study on the significance of serine hydroxymethyl transferase expression and its role in bladder cancer.
Activation of the YY1-UGT2B7 Axis Promotes Mammary Estrogen Homeostasis Dysregulation and Exacerbates Breast Tumor Metastasis.
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
A Regulator Role for the ATP-Binding Cassette Subfamily C Member 6 Transporter in HepG2 Cells: Effect on the Dynamics of Cell-Cell and Cell-Matrix Interactions.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Mechanical confinement promotes heat resistance of hepatocellular carcinoma via SP1/IL4I1/AHR axis.
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression.
Comprehensive Characterization of Ageing-Relevant Subtypes Associated With Different Tumorigenesis and Tumor Microenvironment in Prostate Cancer.
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.
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Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.
The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway.
Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration.
Allergy-induced systemic inflammation impairs tendon quality.
Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
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Mechanism of Ulcerative Colitis-Aggravated Liver Fibrosis: The Activation of Hepatic Stellate Cells and TLR4 Signaling Through Gut-Liver Axis.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non-carcinogenic L929 fibroblast cells.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
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Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
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Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
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Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
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Mechanical confinement promotes heat resistance of hepatocellular carcinoma via SP1/IL4I1/AHR axis.
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Frontiers in molecular biosciences 2022;9:803474
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
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Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.
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Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
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The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
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Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.
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European journal of pharmacology 2022 Jan 15;915:174601
CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.
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Frontiers in cardiovascular medicine 2021;8:732122
Frontiers in cardiovascular medicine 2021;8:732122
Mechanism of Ulcerative Colitis-Aggravated Liver Fibrosis: The Activation of Hepatic Stellate Cells and TLR4 Signaling Through Gut-Liver Axis.
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Frontiers in physiology 2021;12:695019
Frontiers in physiology 2021;12:695019
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
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Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
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Experimental cell research 2021 Sep 1;406(1):112735
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Chemico-biological interactions 2021 Oct 1;348:109648
Increased expression of TAZ and associated upregulation of PD-L1 in cervical cancer.
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Cancer cell international 2021 Nov 4;21(1):592
Cancer cell international 2021 Nov 4;21(1):592
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International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
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Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
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International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non-carcinogenic L929 fibroblast cells.
Li X, Zhou X, Liu Y, Fan J, Huo H, Yao J, Wang L, Ma N
Oncology letters 2021 Jan;21(1):44
Oncology letters 2021 Jan;21(1):44
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
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Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
Fu H, Chen R, Wang Y, Xu Y, Xia C, Zhang B
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
Li D, Zhang J, Yang J, Wang J, Zhang R, Li J, Zhang R
Cell death & disease 2021 Dec 20;13(1):12
Cell death & disease 2021 Dec 20;13(1):12
Scleraxis expressing scleral cells respond to inflammatory stimulation.
Atta G, Schroedl F, Kaser-Eichberger A, Spitzer G, Traweger A, Heindl LM, Tempfer H
Histochemistry and cell biology 2021 Aug;156(2):123-132
Histochemistry and cell biology 2021 Aug;156(2):123-132
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
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Frontiers in oncology 2020;10:544288
Frontiers in oncology 2020;10:544288
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
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Cell reports 2020 Oct 27;33(4):108327
Cell reports 2020 Oct 27;33(4):108327
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399
Cell death & disease 2020 May 26;11(5):399
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
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Biomaterials 2020 Aug;249:120034
Biomaterials 2020 Aug;249:120034
Enhancement of Histone Deacetylase Inhibitor Sensitivity in Combination with Cyclin-Dependent Kinase Inhibition for the Treatment of Oral Squamous Cell Carcinoma.
Zhao B, Huang Z, Qin Z, Li Y, Wang T, Wang L, Zhou W, Yu C, Wang X, Yang S, Fan Y, Xiang R
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):141-156
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):141-156
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Tran BH, Yu Y, Chang L, Tan B, Jia W, Xiong Y, Dai T, Zhong R, Zhang W, Le VM, Rose P, Wang Z, Mao Y, Zhu YZ
International journal of nanomedicine 2019;14:10061-10077
International journal of nanomedicine 2019;14:10061-10077
α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injury.
Mei Z, Tian X, Chen J, Wang Y, Yao Y, Li X, Yang C, Zhang S, Xie C
Oncology reports 2018 Oct;40(4):2287-2297
Oncology reports 2018 Oct;40(4):2287-2297
Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis.
Zhang Y, Huang P, Liu X, Xiang Y, Zhang T, Wu Y, Xu J, Sun Z, Zhen W, Zhang L, Si Y, Liu Y
Journal of pharmacological sciences 2018 Jul;137(3):305-312
Journal of pharmacological sciences 2018 Jul;137(3):305-312
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Wang S, Shen Y, Qiu R, Chen Z, Chen Z, Chen W
International journal of oncology 2017 Aug;51(2):615-624
International journal of oncology 2017 Aug;51(2):615-624
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