M00139

antibody from Boster Biological Technology

Targeting: MMP9 CLG4B

Provider product page for M00139

Western blot

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [32]
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Validations
Immunohistochemistry [1]

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Product number: M00139 - Provider product page
Provider: Boster Biological Technology
Product name: Anti-MMP9 Rabbit Monoclonal Antibody
Antibody type: Monoclonal
Description: Monoclonal antibody for MMP 9/MMP9 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IF, IHC, ICC, WB. Reactive species: Human, Rat MMP 9/MMP9 information: Molecular Weight: 78458 MW; Subcellular Localization: Secreted, extracellular space, extracellular matrix ; Tissue Specificity: Produced by normal alveolar macrophages and granulocytes.
Reactivity: Human, Rat
Host: Rabbit
Antibody clone number: BCD-13
Vial size: 100ug/vial
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

MMP9 protein structure - M00139 shown in red.

Submitted references miR-769-3p inhibits cellular proliferation of KSHV-infected SH-SY5Y cells through targeting mTOR.

Cao D, Wu Z, Yang R, Yao L, Huang J, Ding Y, Ruzi A, Pan Z, Pan Y, Li D, Gu W, Zhang J
Journal of Cancer 2024;15(11):3338-3349

Intracranial aneurysm circulating exosome-derived LncRNA ATP1A1-AS1 promotes smooth muscle cells phenotype switching and apoptosis.

Wang C, Li H, Zhou H, Xu Y, Li S, Zhu M, Yu B, Feng Y
Aging 2024 May 8;16(9):8320-8335

Somatic PDGFRB activating variants promote smooth muscle cell phenotype modulation in intracranial fusiform aneurysm.

Hao L, Ya X, Wu J, Tao C, Ma R, Zheng Z, Mou S, Ling Y, Yang Y, Wang J, Zhang Y, Lin Q, Zhao J
Journal of biomedical science 2024 May 13;31(1):51

Enhancing RECK Expression Through miR-21 Inhibition: A Promising Strategy for Bladder Carcinoma Control.

Dos Santos PRM, da Silva Gomes PR, Romão P, Maluf FC, Guimarães VR, Candido P, Gonçalves GL, de Camargo JA, Dos Santos GA, Silva I, Leite KRM, Nahas W, Reis ST, Pimenta R, Viana NI
Biochemical genetics 2024 Mar 24;

A breakthrough in periodontitis treatment: Revealing the pharmacodynamic substances and mechanisms of Kouqiangjie formula.

Wu Y, Liu M, He X, Zhou H, Wei J, Li H, Yuan Q, Zuo Y, Zhao L, Xie Y
Journal of ethnopharmacology 2024 Apr 6;323:117738

Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.

Xu H, Li L, Wang S, Wang Z, Qu L, Wang C, Xu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940

Evaluation of the therapeutic effects of oestradiol on the systemic inflammatory response and on lung injury caused by the occlusion of the proximal descending aorta in male rats.

de Sousa MN, da Anunciação LF, de Freitas PLZ, Ricardo-da-Silva FY, Moreira LFP, Correia CJ, Breithaupt-Faloppa AC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2023 Sep 7;64(3)

The Effect of Gene Editing by CRISPR-Cas9 of miR-21 and the Indirect Target MMP9 in Metastatic Prostate Cancer.

Camargo JA, Viana NI, Pimenta R, Guimarães VR, Dos Santos GA, Candido P, Ghazarian V, Romão P, Silva IA, Birbrair A, Srougi M, Nahas WC, Leite KR, Trarbach EB, Reis ST
International journal of molecular sciences 2023 Oct 3;24(19)

Timosaponin BII inhibits TGF-β mediated epithelial-mesenchymal transition through Smad-dependent pathway during pulmonary fibrosis.

Ding D, Shen X, Yu L, Zheng Y, Liu Y, Wang W, Liu L, Zhao Z, Nian S, Liu L
Phytotherapy research : PTR 2023 Jul;37(7):2787-2799

The involvement of MALAT1-ALKBH5 signaling axis into proliferation and metastasis of human papillomavirus-positive cervical cancer.

Wu S, Liu L, Xu H, Zhu Q, Tan M
Cancer biology & therapy 2023 Dec 31;24(1):2249174

Effect and mechanism of safranal on ISO-induced myocardial injury based on network pharmacology.

Yan M, Zhao J, Kang Y, Liu L, He W, Xie Y, Wang R, Shan L, Li X, Ma K
Journal of ethnopharmacology 2023 Apr 6;305:116103

Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway.

Hongxia G, Xiaojie J, Guangxian L, Min Z, Shiwei N, Wangjie C, Han Z, Yuanding Z, Chenghao L, Yaling L, Yun S, Yongqi L
Journal of oncology 2022;2022:5497991

miR-34a-5p inhibits the malignant progression of KSHV-infected SH-SY5Y cells by targeting c-fos.

Wu S, Wu Z, Xu H, Zhang J, Gu W, Tan X, Pan Z, Cao D, Li D, Yang L, Li D, Pan Y
PeerJ 2022;10:e13233

Microglia Regulate Blood-Brain Barrier Integrity via MiR-126a-5p/MMP9 Axis during Inflammatory Demyelination.

Yu Z, Fang X, Liu W, Sun R, Zhou J, Pu Y, Zhao M, Sun D, Xiang Z, Liu P, Ding Y, Cao L, He C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105442

Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model.

Liang Q, Lin Q, Li Y, Luo W, Huang X, Jiang Y, Qin C, Nong J, Chen X, Sooranna SR, Pinhu L
Journal of immunology research 2020;2020:6644687

Low expression of RECK in oral squamous cell carcinoma patients induces a shorter survival rate through an imbalance of RECK/MMPs.

Yuan J, Li W, Zhu J, Deng S, Tao X
International journal of clinical and experimental pathology 2020;13(3):501-508

Changes in expressions of miR-22-3p and MMP-9 in rats with thoracic aortic aneurysm and their significance.

Zhao HM, Jin L, Liu Y, Hong X
European review for medical and pharmacological sciences 2020 Jun;24(12):6949-6954

The overexpression of uPA promotes the proliferation and fibrinolytic activity of human umbilical vein endothelial cells.

Song T, Meng S, Xu ST, Jin SJ, Zeng QZ, Gu GJ
International journal of clinical and experimental pathology 2019;12(8):2959-2966

Untangling the response of bone tumor cells and bone forming cells to matrix stiffness and adhesion ligand density by means of hydrogels.

Jiang T, Zhao J, Yu S, Mao Z, Gao C, Zhu Y, Mao C, Zheng L
Biomaterials 2019 Jan;188:130-143

Gypsophila elegans isoorientin-2″-O-α-l-arabinopyranosyl ameliorates porcine serum-induced immune liver fibrosis by inhibiting NF-κB signaling pathway and suppressing HSC activation.

Bai F, Huang Q, Wei J, Lv S, Chen Y, Liang C, Wei L, Lu Z, Lin X
International immunopharmacology 2018 Jan;54:60-67

Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.

Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J
Oncotarget 2017 Sep 8;8(38):63461-63483

RUNX3 plays a tumor suppressor role by inhibiting cell migration, invasion and angiogenesis in oral squamous cell carcinoma.

Zhou WN, Du YF, Bai J, Song XM, Zheng Y, Yuan H, Zhang W, Zhang ZD, Wu YN
Oncology reports 2017 Oct;38(4):2378-2386

Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.

Zhang Y, Liu Y, Zou J, Yan L, Du W, Zhang Y, Sun H, Lu P, Geng S, Gu R, Zhang H, Bi Z
Oncotarget 2017 Oct 31;8(53):91134-91149

Growth differentiation factor 15 induces growth and metastasis of human liver cancer stem-like cells via AKT/GSK-3β/β-catenin signaling.

Xu Q, Xu HX, Li JP, Wang S, Fu Z, Jia J, Wang L, Zhu ZF, Lu R, Yao Z
Oncotarget 2017 Mar 7;8(10):16972-16987

Effect of crocetin on vascular smooth muscle cells migration induced by advanced glycosylation end products.

Xiang M, Yang R, Zhang Y, Wu P, Wang L, Gao Z, Wang J
Microvascular research 2017 Jul;112:30-36

Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway.

Huang KF, Huang XP, Xiao GQ, Yang HY, Lin JS, Diao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 May;68(4):455-61

Expression of the tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction.

Jia ZB, Tian H, Kang K, Miao HZ, Liu KY, Jiang SL, Wang LP
Transplant immunology 2014 May;30(4):149-58

Differential effects of sulfated triterpene glycosides, holothurin A1, and 24-dehydroechinoside A, on antimetastasic activity via regulation of the MMP-9 signal pathway.

Zhao Q, Xue Y, Liu ZD, Li H, Wang JF, Li ZJ, Wang YM, Dong P, Xue CH
Journal of food science 2010 Nov-Dec;75(9):H280-8

Prevention of osteoporosis in mice after ovariectomy via allograft of microencapsulated ovarian cells.

Guo XX, Zhou JL, Xu Q, Lu X, Liang YJ, Weng J, Shi XL
Anatomical record (Hoboken, N.J. : 2007) 2010 Feb;293(2):200-7

Adenovirus-mediated transfer of siRNA against PAI-1 mRNA ameliorates hepatic fibrosis in rats.

Hu PF, Chen H, Zhong W, Lin Y, Zhang X, Chen YX, Xie WF
Journal of hepatology 2009 Jul;51(1):102-13

IL-17 stimulates migration of carotid artery vascular smooth muscle cells in an MMP-9 dependent manner via p38 MAPK and ERK1/2-dependent NF-kappaB and AP-1 activation.

Cheng G, Wei L, Xiurong W, Xiangzhen L, Shiguang Z, Songbin F
Cellular and molecular neurobiology 2009 Dec;29(8):1161-8

Increased expression and activity of MMP-9 in C-reactive protein- induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B.

Sheng F, Cheng L, Zeng Q, Gao W
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2009 Aug;29(4):399-403

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Submitted by: Boster Biological Technology (provider)
Main image
Experimental details: Immunohistochemical analysis of paraffin-embedded human colon cancer, using MMP9 Antibody.
Additional image