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- References [1089]
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- Product number
- 10375-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10375-2-AP, RRID:AB_10897178
- Product name
- MMP9 (N-terminal) antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MMP9 (N-terminal) antibody (Cat. #10375-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Developmental Regulation of Matrix Metalloproteinases in Response to Multifactorial, Severe Traumatic Brain Injuries during Immaturity.
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
circTADA2A inhibited SLC38A1 expression and suppresses melanoma progression through the prevention of CNBP trans-activation.
Proteomics study the potential targets for Rifampicin-resistant spinal tuberculosis.
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150-5p/ADAM19 axis.
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
A double-network porous hydrogel based on high internal phase emulsions as a vehicle for potassium sucrose octasulfate delivery accelerates diabetic wound healing.
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment.
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows.
Protective effects of sugarcane polyphenol against UV-B-induced photoaging in Balb/c mouse skin: Antioxidant, anti-inflammatory, and anti-glycosylation Effects.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress.
Arenobufagin inhibits lung metastasis of colorectal cancer by targeting c-MYC/Nrf2 axis.
LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1.
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway.
Abundant Neutrophil-Initiated Acute Myocardial Injury Following Coxsackievirus A6 Infection.
A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression.
Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study.
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Rescuing Nucleus Pulposus Cells from ROS Toxic Microenvironment via Mitochondria-Targeted Carbon Dot-Supported Prussian Blue to Alleviate Intervertebral Disc Degeneration.
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation.
Network pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis.
Exploring the molecular mechanism of Artemisia rupestris L. for the treatment of hepatocellular carcinoma via PI3K/AKT pathway.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
BI-3231, an enzymatic inhibitor of HSD17B13, reduces lipotoxic effects induced by palmitic acid in murine and human hepatocytes.
Dimethyl α-Ketoglutarate Promotes the Synthesis of Collagen and Inhibits Metalloproteinases in HaCaT Cells.
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
ID2 promotes tumor progression and metastasis in thyroid cancer.
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis.
ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
FLNA overexpression promotes papillary thyroid cancer aggression via the FAK/AKT signaling pathway.
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood-Brain Barrier in vitro.
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner.
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Discovery of Novel 2-Oxoacetamide Derivatives as B3GAT3 Inhibitors for the Treatment of Hepatocellular Carcinoma.
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
KRT80 expression works as a biomarker and a target for differentiation in gastric cancer.
IL-21 promoting angiogenesis contributes to the development of psoriasis.
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Upregulation of miR-20b-5p inhibits trophoblast invasion by blocking autophagy in recurrent miscarriage.
Intervention with extracellular matrix metalloproteinase inducer in osteoclasts attenuates periodontitis-induced bone resorption.
MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC).
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging.
Bardoxolone methyl breaks the vicious cycle between M1 macrophages and senescent nucleus pulposus cells through the Nrf2/STING/NF-κB pathway.
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
DUSP22 suppresses tumor progression by directly dephosphorylating AKT in non-small cell lung cancer.
Matrix metalloproteinase-9 inhibition prevents aquaporin-4 depolarization-mediated glymphatic dysfunction in Parkinson's disease.
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation.
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Loureirin A Promotes Cell Differentiation and Suppresses Migration and Invasion of Melanoma Cells via WNT and AKT/mTOR Signaling Pathways.
Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway.
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Nupr1-mediated vascular smooth muscle cell phenotype transformation involved in methamphetamine induces pulmonary hypertension.
Fluvastatin prevents lung metastasis in triple-negative breast cancer by triggering autophagy via the RhoB/PI3K/mTOR pathway.
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
PFKFB3 facilitates cell proliferation and migration in anaplastic thyroid carcinoma via the WNT/β-catenin signaling pathway.
A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis.
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
The role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression.
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Activation of the YY1-UGT2B7 Axis Promotes Mammary Estrogen Homeostasis Dysregulation and Exacerbates Breast Tumor Metastasis.
Association of GAL-8 promoter methylation levels with coronary plaque inflammation.
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
TREM2 as an independent predictor of poor prognosis promotes the migration via the PI3K/AKT axis in prostate cancer.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Inhibition of Non-small Cell Lung Cancer by Ferroptosis and Apoptosis Induction through P53 and GSK-3β/Nrf2 Signal Pathways using Qingrehuoxue Formula.
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
A Prognostic Model of Angiogenesis and Neutrophil Extracellular Traps Related Genes Manipulating Tumor Microenvironment in Colon Cancer.
Characterisation of macrophage infiltration and polarisation based on integrated transcriptomic and histological analyses in Primary Sjögren's syndrome.
Pan-cancer analysis shows that IBSP is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including osteosarcoma.
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Diabetes mellitus induces a novel inflammatory network involving cancer progression: Insights from bioinformatic analysis and in vitro validation.
Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data.
Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury.
Circ_0000231 promotes paclitaxel resistance in ovarian cancer by regulating miR-140/RAP1B.
Crosstalk between septic shock and venous thromboembolism: a bioinformatics and immunoassay analysis.
Identifying key transcription factors and immune infiltration in non-small-cell lung cancer using weighted correlation network and Cox regression analyses.
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
TGF-β1 mediates tumor immunosuppression aggravating at the late stage post-high-light-dose photodynamic therapy.
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
MMP9-Responsive Graphene Oxide Quantum Dot-Based Nano-in-Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization.
Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathway.
N-Acetylcysteine-Derived Carbon Dots for Free Radical Scavenging in Intervertebral Disc Degeneration.
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
Dendrobium nobile Lindl Polysaccharides Attenuate UVB-induced Photodamage by Regulating Oxidative Stress, Inflammation and MMPs Expression in Mice Model.
CSNK2A2 promotes hepatocellular carcinoma progression through activation of NF-κB pathway.
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
TSPAN8 regulates EGFR/AKT pathway to enhance metastasis in gastric cancer.
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
RRAGB-mediated suppression of PI3K/AKT exerts anti-cancer role in glioblastoma.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway.
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth.
The Effect of Adipocyte-Secreted Factors in Activating Focal Adhesion Kinase-Mediated Cell Signaling Pathway towards Metastasis in Breast Cancer Cells.
A Regulator Role for the ATP-Binding Cassette Subfamily C Member 6 Transporter in HepG2 Cells: Effect on the Dynamics of Cell-Cell and Cell-Matrix Interactions.
Aquaporin 9 causes recurrent spontaneous abortion by inhibiting trophoblast cell epithelial-mesenchymal transformation and invasion through the PI3K/AKT pathway†.
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
NONHSAG028908.3 sponges miR‑34a‑5p to promote growth of colorectal cancer via targeting ALDOA.
Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma.
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression.
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy.
Aristolocholic acid I promotes renal tubular epithelial fibrosis by upregulating matrix metalloproteinase-9 expression via activating the C3a/C3aR axis of macrophages.
Toxicity mechanism of peri-implantation pesticide beta-cypermethrin exposure on endometrial remodeling in early pregnant mice.
A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer.
LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Improving ocular bioavailability of hydrophilic drugs through dynamic covalent complexation.
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
Sinomenine promotes flap survival by upregulating eNOS and eNOS-mediated autophagy via PI3K/AKT pathway.
Exploring the mechanism of Xingpi Capsule in diarrhea predominant-irritable bowel syndrome treatment based on multiomics technology.
Fibroblast-Derived Extracellular Vesicle-Packaged Long Noncoding RNA Upregulated in Diabetic Skin Enhances Keratinocyte MMP-9 Expression and Delays Diabetic Wound Healing.
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Ceramide Synthase 1 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Interacting with USP14 and Downregulating the PI3K/AKT/mTOR Signaling Pathway.
[DTX2 overexpression promotes migration and invasion of colorectal cancer cells through the Notch2/Akt axis].
Rab32 promotes glioblastoma migration and invasion via regulation of ERK/Drp1-mediated mitochondrial fission.
Integrated miRNA and mRNA omics reveal dioscin suppresses migration and invasion via MEK/ERK and JNK signaling pathways in human endometrial carcinoma in vivo and in vitro.
Reduced inhibitory and excitatory input onto parvalbumin interneurons mediated by perineuronal net might contribute to cognitive impairments in a mouse model of sepsis-associated encephalopathy.
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Albumin fusion with human lactoferrin shows enhanced inhibition of cancer cell migration.
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2.
m(6)A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Tanshinone IIA suppresses burning incense-induced oxidative stress and inflammatory pathways in astrocytes.
Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways.
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO.
Self-powered enzyme-linked microneedle patch for scar-prevention healing of diabetic wounds.
Hyperin promotes proliferation, migration, and invasion of HTR-8/SVneo trophoblast cells via activation of JAK1/STAT3 pathway in recurrent spontaneous abortions.
Mast cell stabilization: new mechanism underlying the therapeutic effect of intense pulsed light on rosacea.
Aiphanol, a multi-targeting stilbenolignan, potently suppresses mouse lymphangiogenesis and lymphatic metastasis.
Cellular-scale sex differences in extracellular matrix remodeling by valvular interstitial cells.
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Protein kinase D1 promotes the survival of random-pattern skin flaps in rats.
Simple Nano-Luciferase-Based Assay for the Rapid and High-Throughput Detection of SARS-CoV-2 3C-Like Protease.
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
A Systemic and Integrated Analysis of p63-Driven Regulatory Networks in Mouse Oral Squamous Cell Carcinoma.
Anti-inflammation and anti-aging mechanisms of mercaptopurine in vivo and in vitro.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Hydrogen attenuates postoperative pain through Trx1/ASK1/MMP9 signaling pathway.
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Silencing of FAM111B inhibited proliferation, migration and invasion of hepatoma cells through activating p53 pathway.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives.
LINC01060 knockdown inhibits osteosarcoma cell malignant behaviors in vitro and tumor growth and metastasis in vivo through the PI3K/Akt signaling.
Tetrahydropalmatine: Orchestrating survival - Regulating autophagy and apoptosis via the PI3K/AKT/mTOR pathway in perforator flaps.
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34.
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
LncRNA NEAT1: A novel regulator associated with the inflammatory response in acute respiratory distress syndrome.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function.
ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Knockdown of Krüppel-Like Factor 9 Inhibits Aberrant Retinal Angiogenesis and Mitigates Proliferative Diabetic Retinopathy.
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell.
Circular RNA circ0104103 inhibits colorectal cancer progression through interactions with HuR and miR-373-5p.
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation.
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Effects of limonin treatment on the survival of random skin flaps in mice.
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
HMGA1 As a Potential Prognostic and Therapeutic Biomarker in Breast Cancer.
TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia.
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
Guanxinning Tablet Attenuates Coronary Atherosclerosis via Regulating the Gut Microbiota and Their Metabolites in Tibetan Minipigs Induced by a High-Fat Diet.
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression.
Oxymatrine Protects Chondrocytes against IL-1β-triggered Apoptosis in Vitro and Inhibits Osteoarthritis in Mice Model.
GLP-1 RA Improves Diabetic Retinopathy by Protecting the Blood-Retinal Barrier through GLP-1R-ROCK-p-MLC Signaling Pathway.
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin.
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Gab1 regulates invadopodia and autocrine VEGF through SHP2/ERK1/2 in hilar cholangiocarcinoma cells.
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
A novel hypoxia-driven gene signature that can predict the prognosis and drug resistance of gliomas.
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells.
ABCA12 Promotes Proliferation and Migration and Inhibits Apoptosis of Pancreatic Cancer Cells Through the AKT Signaling Pathway.
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss.
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Supercritical fluid extract of Angelica sinensis promotes the anti-colorectal cancer effect of oxaliplatin.
A multi-targeting natural product, aiphanol, inhibits tumor growth and metastasis.
RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair.
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Deficient DNASE1L3 facilitates neutrophil extracellular traps-induced invasion via cyclic GMP-AMP synthase and the non-canonical NF-κB pathway in diabetic hepatocellular carcinoma.
Ectopic Endometrial Cell-Derived Exosomal Moesin Induces Eutopic Endometrial Cell Migration, Enhances Angiogenesis and Cytosolic Inflammation in Lesions Contributes to Endometriosis Progression.
Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation.
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome.
Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model.
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
Design, Synthesis, and Biological Evaluation of Dual-Target COX-2/CYP51 Inhibitors for the Treatment of Fungal Infectious Diseases.
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
A Novel lncRNA Mediates the Delayed Tooth Eruption of Cleidocranial Dysplasia.
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development.
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway.
Belinostat (PXD101) resists UVB irradiation-induced cellular senescence and skin photoaging.
Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma.
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Multipronged Micelles-Hydrogel for Targeted and Prolonged Drug Delivery in Chronic Wound Infections.
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Synergistic anti-inflammatory effect of gut microbiota and lithocholic acid on liver fibrosis.
STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer.
Analysis of meat color, meat tenderness and fatty acid composition of meat in second filial hybrid offspring of MSTN mutant pigs.
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
A novel Granzymes and miRNA nanocapsules co-delivery system for tumor suppression.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Role of Wnt/β-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1.
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
The anti-inflammation effect of strontium ranelate on rat chondrocytes with or without IL-1β in vitro.
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways.
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury.
Expressions and significances of CTSL, the target of COVID-19 on GBM.
Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu).
Periodontopathic Bacterium Fusobacterium nucleatum Affects Matrix Metalloproteinase-9 Expression in Human Alveolar Epithelial Cells and Mouse Lung.
The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation.
Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production.
Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway.
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Early mobilization in spinal cord injury promotes changes in microglial dynamics and recovery of motor function.
The molecular mechanism of baicalein repressing progression of gastric cancer mediating miR-7/FAK/AKT signaling pathway.
Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Coordination of Osteoblastogenesis and Osteoclastogenesis by the Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Matrix To Promote Bone Regeneration.
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling.
Metabolic Intervention Nanoparticles for Triple-Negative Breast Cancer Therapy via Overcoming FSP1-Mediated Ferroptosis Resistance.
Canthin-6-one (CO) from Picrasma quassioides (D.Don) Benn. ameliorates lipopolysaccharide (LPS)-induced astrocyte activation and associated brain endothelial disruption.
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.
Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
MiR-665 suppresses the progression of diffuse large B cell lymphoma (DLBCL) through targeting LIM and SH3 protein 1 (LASP1).
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Salidroside Promotes Sensitization to Doxorubicin in Human Cancer Cells by Affecting the PI3K/Akt/HIF Signal Pathway and Inhibiting the Expression of Tumor-Resistance-Related Proteins.
TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer.
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
Long Noncoding RNA HAND2-AS1 Suppresses Cell Proliferation, Migration, and Invasion of Bladder Cancer via miR-17-5p/KLF9 Axis.
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
IL-38-mediated NLRP3/caspase-1 inhibition is a disease-modifying treatment for TMJ inflammation.
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer.
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment.
A yes-associated protein 1- Notch1 receptor positive feedback loop promotes breast cancer lung metastasis by attenuating the bone morphogenetic protein 4-SMAD family member 1/5 signaling.
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Ovarian tissue transplantation ameliorates osteoporosis and dyslipidaemia in ovariectomised mice.
Multi-specific niflumic acid platinum(IV) complexes displaying potent antitumor activities by improving immunity and suppressing angiogenesis besides causing DNA damage.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Titania-Nanotube-Coated Titanium Substrates Promote Osteogenesis and Suppress Osteoclastogenesis via Integrin ανβ3.
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Macrophage Nuclear Receptor Corepressor 1 Deficiency Protects Against Ischemic Stroke in Mice.
Glycometabolic reprogramming-mediated proangiogenic phenotype enhancement of cancer-associated fibroblasts in oral squamous cell carcinoma: role of PGC-1α/PFKFB3 axis.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.
Development of a series of flurbiprofen and zaltoprofen platinum(IV) complexes with anti-metastasis competence targeting COX-2, PD-L1 and DNA.
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
SEZ6L2, regulated by USF1, accelerates the growth and metastasis of breast cancer.
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
miR-340-5p affects oral squamous cell carcinoma (OSCC) cells proliferation and invasion by targeting endoplasmic reticulum stress proteins.
LINC00022 acts as an oncogene in colorectal cancer progression via sponging miR-375-3p to regulate FOXF1 expression.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer.
A novel promoter-associated non-coding small RNA paGLI1 recruits FUS/P65 to transactivate GLI1 gene expression and promotes infiltrating glioma progression.
Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis.
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
Sacubitril Ameliorates Cardiac Fibrosis Through Inhibiting TRPM7 Channel.
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
miR-539 Targeting SNAI2 Regulates MMP9 Signaling Pathway and Affects Blood-Brain Barrier Permeability in Cerebrovascular Occlusive Diseases: A Study Based on Head and Neck Ultrasound and CTA.
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC).
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway.
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.
Biphasic Effect of Pirfenidone on Angiogenesis.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer.
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Osteosarcoma Cell-Derived Small Extracellular Vesicles Enhance Osteoclastogenesis and Bone Resorption Through Transferring MicroRNA-19a-3p.
LncRNA FENDRR in Carcinoma-Associated Fibroblasts Regulates the Angiogenesis of Oral Squamous Cell Carcinoma Through the PI3K/AKT Pathway.
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
Tenascin-C regulates migration of SOX10 tendon stem cells via integrin-α9 for promoting patellar tendon remodeling.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Inhibition of ACLY Leads to Suppression of Osteoclast Differentiation and Function Via Regulation of Histone Acetylation.
Effects of endurance exercise on serum inflammatory cytokine level and kidney structure in a rat diabetes model.
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Study on the potential nephrotoxicity and mutagenicity of aristolochic acid IVa and its mechanism.
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90.
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2.
Circular RNA Paired-Related Homeobox 1 Promotes Gastric Carcinoma Cell Progression via Regulating MicroRNA-665/YWHAZ Axis.
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway.
Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.
Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity.
circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression.
Decreased endostatin in db/db retinas is associated with optic disc intravitreal vascularization.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment.
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Strontium ranelate promotes chondrogenesis through inhibition of the Wnt/β-catenin pathway.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
CHRDL2 promotes osteosarcoma cell proliferation and metastasis through the BMP-9/PI3K/AKT pathway.
Syndecan-3 contributes to the regulation of the microenvironment at the node of Ranvier following end-to‑side neurorrhaphy: sodium image analysis.
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Decursin inhibits the growth of HeLa cervical cancer cells through PI3K/Akt signaling.
Quercetin inhibits invasion and angiogenesis of esophageal cancer cells.
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Impairment of corneal epithelial wound healing is association with increased neutrophil infiltration and reactive oxygen species activation in tenascin X-deficient mice.
IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.
COL5A1 Variants Cause Aortic Dissection by Activating TGF-β-Signaling Pathway.
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3β/ZEB1 pathway.
Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ Prolapse.
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation.
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Melittin inhibits lung metastasis of human osteosarcoma: Evidence of wnt/β-catenin signaling pathway participation.
Upregulation of Rpn10 promotes tumor progression via activation of the NF-κB pathway in clear cell renal cell carcinoma.
Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability.
Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
Abiotic Mimic of Matrix Metalloproteinase-9 Inhibitor against Advanced Metastatic Cancer.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition.
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Sulforaphane Inhibits Osteoclastogenesis via Suppression of the Autophagic Pathway.
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Identification of Key Candidate Genes Involved in the Progression of Idiopathic Pulmonary Fibrosis.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Dual-targeting tumor cells and tumor associated macrophages with lipid coated calcium zoledronate for enhanced lung cancer chemoimmunotherapy.
EG-VEGF Induces Invasion of a Human Trophoblast Cell Line via PROKR2.
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2.
YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.
MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway.
Expression of matrix metalloproteinases during axonal regeneration in the goldfish spinal cord.
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway.
Uncovering the anti-NSCLC effects and mechanisms of gypenosides by metabolomics and network pharmacology analysis.
Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response.
Arsenic-induced lung inflammation and fibrosis in a rat model: Contribution of the HMGB1/RAGE, PI3K/AKT, and TGF-β1/SMAD pathways.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway.
Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway.
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
The protective effect of HOXA5 on carotid atherosclerosis occurs by modulating the vascular smooth muscle cell phenotype.
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Nitric oxide mediates disruption of human placental trophoblast invasion induced by perfluorobutane sulfonate.
Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model.
Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway.
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model.
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Screening and identification of haptoglobin showing its important role in pathophysiological process of gallbladder carcinoma.
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Oncometabolite L-2-hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Matrix Metalloproteinase 9 is Regulated by LOX-1 and erk1/2 Pathway in Dental Peri-Implantitis.
Morusin Inhibits Human Osteosarcoma via the PI3K-AKT Signaling Pathway.
Knockdown of Matrix Metallopeptidase 9 Inhibits Metastasis of Oral Squamous Cell Carcinoma Cells in a Zebrafish Xenograft Model.
Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells.
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
5-HT(7) Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells.
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
Hydroxysafflor yellow A promotes multiterritory perforating flap survival: an experimental study.
Overexpression of TEM8 promotes ovarian cancer progression via Rac1/Cdc42/JNK and MEK/ERK/STAT3 signaling pathways.
S1PR2 Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation.
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis.
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Cyclin G2 Inhibits Oral Squamous Cell Carcinoma Growth and Metastasis by Binding to IGFBP3 and Regulating the FAK-SRC-STAT Signaling Pathway.
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer.
Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer.
Splenectomy enhances the Ly6C(low) phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis.
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Ziyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells.
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
ERK/AKT Inactivation and Apoptosis Induction Associate With Quetiapine-inhibited Cell Survival and Invasion in Hepatocellular Carcinoma Cells.
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
Estrogen-decreased hsa_circ_0001649 promotes stromal cell invasion in endometriosis.
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p.
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity.
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways.
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway.
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Comparative peptidome profiling reveals critical roles for peptides in the pathology of pancreatic cancer.
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
Glycofullerenes Inhibit Particulate Matter Induced Inflammation and Loss of Barrier Proteins in HaCaT Human Keratinocytes.
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
M2 macrophages promote vasculogenesis during retinal neovascularization by regulating bone marrow-derived cells via SDF-1/VEGF.
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
MicroRNA-382-5p is involved in pulmonary inflammation induced by fine particulate matter exposure.
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation.
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Silencing matrix metalloproteinase 9 exerts a protective effect on astrocytes after oxygen-glucose deprivation and is correlated with suppression of aquaporin-4.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.
KCNN4 promotes invasion and metastasis through the MAPK/ERK pathway in hepatocellular carcinoma.
MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Circular RNA circ_001621 promotes osteosarcoma cells proliferation and migration by sponging miR-578 and regulating VEGF expression.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
CARLo-5 as an oncogenic gene in endometrial carcinoma.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart.
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p.
Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
PRCC-TFE3 regulates migration and invasion of translocation renal cell carcinomas via activation of Drp1-dependent mitochondrial fission.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
MicroRNA-505-3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
MicroRNA-1298-5p inhibits cell proliferation and the invasiveness of bladder cancer cells via down-regulation of connexin 43.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Andrographolide attenuates oxidative stress injury in cigarette smoke extract exposed macrophages through inhibiting SIRT1/ERK signaling.
Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy.
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes.
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
A systems biology approach for defining the potential molecular framework of idiopathic hypereosinophilic syndrome with cutaneous involvement.
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation.
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Enhancement of Histone Deacetylase Inhibitor Sensitivity in Combination with Cyclin-Dependent Kinase Inhibition for the Treatment of Oral Squamous Cell Carcinoma.
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway.
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
SKA1 promotes malignant phenotype and progression of glioma via multiple signaling pathways.
Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA.
Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis.
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway.
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress.
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis.
Downregulation of RAI14 inhibits the proliferation and invasion of breast cancer cells.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Sijunzi decoction may decrease apoptosis via stabilization of the extracellular matrix following cerebral ischaemia-reperfusion in rats.
Hyperoside protects against heart failure-induced liver fibrosis in rats.
Ricolinostat (ACY-1215) inhibits VEGF expression via PI3K/AKT pathway and promotes apoptosis in osteoarthritic osteoblasts.
CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.
Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway.
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice.
Topically Applied Cross-Linked Hyaluronan Attenuates the Formation of Spinal Epidural Fibrosis in a Swine Model of Laminectomy.
Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.
Inhibition of perivascular mast cell activation is involved in the atheroprotective effect of rosiglitazone in apolipoprotein E-deficient mice.
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation.
Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam.
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals.
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway.
Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
miR‑16‑2‑3p inhibits cell proliferation and migration and induces apoptosis by targeting PDPK1 in maxillary primordium mesenchymal cells.
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia.
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer.
AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis.
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib.
TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease.
lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis.
Ectopic expression of CC chemokine receptor 7 promotes prostate cancer cells metastasis via Notch1 signaling.
Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN.
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway.
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-κB pathway activation.
Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-β1/Smad2 signaling pathway.
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Matrix stiffness regulates epithelial-mesenchymal transition via cytoskeletal remodeling and MRTF-A translocation in osteosarcoma cells.
Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
The antimetastatic effect and underlying mechanisms of thioredoxin reductase inhibitor ethaselen.
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Bradykinin promotes proliferation, migration, and invasion of cervical cancer cells through STAT3 signaling pathways.
Inhibition of Fibroblast Growth Factor Receptor by AZD4547 Protects Against Inflammation in Septic Mice.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy.
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone.
Upregulation of fascin-1 is involved in HIF-1α-dependent invasion and migration of hypopharyngeal squamous cell carcinoma.
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway.
Water-Soluble Fullerenol C(60)(OH)(36) toward Effective Anti-Air Pollution Induced by Urban Particulate Matter in HaCaT Cell.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma.
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Dependence of artesunate on long noncoding RNA-RP11 to inhibit epithelial-mesenchymal transition of hepatocellular carcinoma.
Cordycepin suppresses cell proliferation and migration by targeting CLEC2 in human gastric cancer cells via Akt signaling pathway.
Knockdown of long noncoding RNA CCDC144NL-AS1 attenuates migration and invasion phenotypes in endometrial stromal cells from endometriosis†.
Sodium Tanshinone IIA Sulfonate Decreases Cigarette Smoke-Induced Inflammation and Oxidative Stress via Blocking the Activation of MAPK/HIF-1α Signaling Pathway.
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis.
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
MIR-300 in the imprinted DLK1-DIO3 domain suppresses the migration of bladder cancer by regulating the SP1/MMP9 pathway.
Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration.
Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart.
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Predictive and prognostic value of Matrix metalloproteinase (MMP) - 9 in neoadjuvant chemotherapy for triple-negative breast cancer patients.
Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma.
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injury.
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
Arsenic Trioxide Suppressed Migration and Angiogenesis by Targeting FOXO3a in Gastric Cancer Cells.
IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling.
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Exosomes with Highly Angiogenic Potential for Possible Use in Pulp Regeneration.
Combined application of Embelin and tumor necrosis factor-related apoptosis-inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase-induced apoptosis.
TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Molecular Mechanisms Underlying the Inhibitory Effects of Qingzaojiufei Decoction on Tumor Growth in Lewis Lung Carcinoma.
Ginkgetin ameliorates experimental atherosclerosis in rats.
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122.
Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice.
Cinobufacini inhibits epithelial-mesenchymal transition of human hepatocellular carcinoma cells through c-Met/ERK signaling pathway.
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Anticancer Efficacy of Targeted Shikonin Liposomes Modified with RGD in Breast Cancer Cells.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Interference of Notch 1 inhibits the proliferation and invasion of breast cancer cells: Involvement of the β‑catenin signaling pathway.
MEG3 inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells.
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Identification of COL1A1 as an invasion‑related gene in malignant astrocytoma.
Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation.
Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection.
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Ethanol Extract of Root of Prunus persica Inhibited the Growth of Liver Cancer Cell HepG2 by Inducing Cell Cycle Arrest and Migration Suppression.
Corticosteroids effects on LPS-induced rat inflammatory keratocyte cell model.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells.
Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer.
CircHIPK3 sponges miR-558 to suppress heparanase expression in bladder cancer cells.
Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1.
Adipose Progenitor Cell Secretion of GM-CSF and MMP9 Promotes a Stromal and Immunological Microenvironment That Supports Breast Cancer Progression.
BMAL1 facilitates trophoblast migration and invasion via SP1-DNMT1/DAB2IP pathway in recurrent spontaneous abortion.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells.
LOX-1 is involved in IL-1β production and extracellular matrix breakdown in dental peri-implantitis.
PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation.
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice.
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.
MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2.
Synergistic inhibition of migration and invasion of breast cancer cells by dual docetaxel/quercetin-loaded nanoparticles via Akt/MMP-9 pathway.
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
MicroRNA-203 inhibits proliferation and invasion, and promotes apoptosis of osteosarcoma cells by targeting Runt-related transcription factor 2.
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca(2+)-calcineurin-NFATc1 signaling pathway.
Pinus massoniana bark extract inhibits migration of the lung cancer A549 cell line.
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Effects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy.
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Effects of quercetin on proliferation and migration of human glioblastoma U251 cells.
18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Sesamin protects SH-SY5Y cells against mechanical stretch injury and promoting cell survival.
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis.
The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages.
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
HOX Antisense lincRNA HOXA-AS2 Promotes Tumorigenesis of Hepatocellular Carcinoma.
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma.
Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells.
Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling.
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells.
miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.
Effect of AQP9 Expression in Androgen-Independent Prostate Cancer Cell PC3.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway.
Evidence for a role of GPRC6A in prostate cancer metastasis based on case-control and in vitro analyses.
Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing.
Clinical Significance and Roles in Angiogenesis of Circulating Microparticles in Oral Cancer.
MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway.
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis.
MicroRNA-183 functions as the tumor suppressor via inhibiting cellular invasion and metastasis by targeting MMP-9 in cervical cancer.
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells.
Selenium-substituted hydroxyapatite nanoparticles and their in vivo antitumor effect on hepatocellular carcinoma.
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice.
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.
Gab1 regulates proliferation and migration through the PI3K/Akt signaling pathway in intrahepatic cholangiocarcinoma.
Anti-metastatic effects of antrodan, the Antrodia cinnamomea mycelia glycoprotein, in lung carcinoma cells.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis.
Protective effect of simvastatin on impaired intestine tight junction protein ZO-1 in a mouse model of Parkinson's disease.
The co-expression of MMP-9 and Tenascin-C is significantly associated with the progression and prognosis of pancreatic cancer.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Potent effects of dioscin against liver fibrosis.
BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer.
α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway.
Human umbilical cord mesenchymal stem cells promote carcinoma growth and lymph node metastasis when co-injected with esophageal carcinoma cells in nude mice.
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway.
Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries.
Rho GDP dissociation inhibitor beta promotes cell proliferation and invasion by modulating the AKT pathway in hepatocellular carcinoma.
Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling.
Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm.
Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression.
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration.
Up-regulated isocitrate dehydrogenase 1 suppresses proliferation, migration and invasion in osteosarcoma: in vitro and in vivo.
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma.
Proteasome inhibitor MG132 enhances TRAIL-induced apoptosis and inhibits invasion of human osteosarcoma OS732 cells.
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Interferon regulatory factor (IRF)-1 and IRF-2 are associated with prognosis and tumor invasion in HCC.
Chemical composition of total flavonoids from Salvia chinensia Benth and their pro-apoptotic effect on hepatocellular carcinoma cells: potential roles of suppressing cellular NF-κB signaling.
Inhibition of cell migration by ouabain in the A549 human lung cancer cell line.
A case of pulmonary capillary hemangiomatosis with pulmonary fibrosis associated with MMP-9 related pulmonary remodeling.
Hochstetler A, Price G, Baohan A, Li M, Rodriguez Lara F, Lok J, Costine-Bartell B
Developmental neuroscience 2024;46(5):319-332
Developmental neuroscience 2024;46(5):319-332
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Wu T, Liu S, Chen W, Zhao D, Lu Z
International journal of medical sciences 2024;21(2):319-331
International journal of medical sciences 2024;21(2):319-331
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Ren Y, Yu M, Zheng D, He W, Jin J
Archives of medical science : AMS 2024;20(1):233-247
Archives of medical science : AMS 2024;20(1):233-247
circTADA2A inhibited SLC38A1 expression and suppresses melanoma progression through the prevention of CNBP trans-activation.
Zhang L, Zhang L, Zhang C, Shi S, Cao Z, Shao C, Li J, Yang Y, Zhang X, Wang J, Li X
PloS one 2024;19(4):e0301356
PloS one 2024;19(4):e0301356
Proteomics study the potential targets for Rifampicin-resistant spinal tuberculosis.
Wang Y, Yin S, Wang S, Rong K, Meng XH, Zhou H, Jiao L, Hou D, Jiang Z, He J, Mao Z
Frontiers in pharmacology 2024;15:1370444
Frontiers in pharmacology 2024;15:1370444
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150-5p/ADAM19 axis.
Chen YN, Fu XR, Guo H, Fu XY, Shi KS, Gao T, Yu HQ
American journal of cancer research 2024;14(2):809-831
American journal of cancer research 2024;14(2):809-831
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
Dai S, Xu M, Pang Q, Sun J, Lin X, Chu X, Guo C, Xu J
Burns & trauma 2024;12:tkad036
Burns & trauma 2024;12:tkad036
A double-network porous hydrogel based on high internal phase emulsions as a vehicle for potassium sucrose octasulfate delivery accelerates diabetic wound healing.
Wang Z, Sun L, Wang W, Wang Z, Shi G, Dai H, Yu A
Regenerative biomaterials 2024;11:rbae024
Regenerative biomaterials 2024;11:rbae024
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
Liu J, Yang K, Lin X, Xu J, Cui X, Hao J, Wang W, Wang W, Li L, Hao M
Human cell 2024 Sep;37(5):1434-1445
Human cell 2024 Sep;37(5):1434-1445
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment.
Yuan Y, Peng W, Lei J, Zhao Y, Zhao B, Li Y, Wang J, Qu Q
Molecular neurobiology 2024 Oct;61(10):8438-8453
Molecular neurobiology 2024 Oct;61(10):8438-8453
miR-1180 Targets FXYD5 to Regulate Pancreatic Cancer Cells Migration and Invasion.
Xie H, Li J, Lu M, Zhang R, Mao H
Molecular biotechnology 2024 Nov;66(11):3182-3194
Molecular biotechnology 2024 Nov;66(11):3182-3194
PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows.
Mao Y, Su C, Yang H, Ma X, Zhao F, Qu B, Yang Y, Hou X, Zhao B, Cui Y
Animal biotechnology 2024 Nov;35(1):2314100
Animal biotechnology 2024 Nov;35(1):2314100
Protective effects of sugarcane polyphenol against UV-B-induced photoaging in Balb/c mouse skin: Antioxidant, anti-inflammatory, and anti-glycosylation Effects.
Wang J, Wang M, Zhang C, Li W, Zhang T, Zhou Y, Flavel M, Xi Y, Li H, Liu X
Journal of food science 2024 May;89(5):3048-3063
Journal of food science 2024 May;89(5):3048-3063
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress.
Wu LH, Cheng YW, Lin FL, Hsu KC, Wang MH, Yen JL, Wang TJ, Lin TE, Liu YC, Huang WJ, Hsiao G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116538
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116538
Arenobufagin inhibits lung metastasis of colorectal cancer by targeting c-MYC/Nrf2 axis.
Wang M, Hu S, Yang J, Yuan L, Han L, Liang F, Zhang F, Zhao H, Liu Y, Gao N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155391
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155391
LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1.
Wang X, Liu D, Hua K, Fang L
Cellular signalling 2024 May;117:111112
Cellular signalling 2024 May;117:111112
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28
Military Medical Research 2024 May 6;11(1):28
Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway.
Wang L, Chen L, Schlenk D, Li F, Liu J
The Science of the total environment 2024 May 20;926:172015
The Science of the total environment 2024 May 20;926:172015
Abundant Neutrophil-Initiated Acute Myocardial Injury Following Coxsackievirus A6 Infection.
Zhang Y, Chen S, Sun T, Duan G, Yang H, Feng H, Jiang W, Li D, Ji W, Zhu P, Jin Y
The Journal of infectious diseases 2024 May 15;229(5):1440-1450
The Journal of infectious diseases 2024 May 15;229(5):1440-1450
A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression.
Wu H, Yang Z, Chang C, Wang Z, Zhang D, Guo Q, Zhao B
Cancer cell international 2024 May 11;24(1):168
Cancer cell international 2024 May 11;24(1):168
Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Chang R, Su Y, Kong H, Wang F, Xing Y, Jiang L, Xin H
Molecular biotechnology 2024 Mar;66(3):531-543
Molecular biotechnology 2024 Mar;66(3):531-543
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study.
Wang G, Ma C, Mo L, Chen J, Yuan J, Xu J, He W
Journal of orthopaedic translation 2024 Mar;45:178-187
Journal of orthopaedic translation 2024 Mar;45:178-187
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y
The FEBS journal 2024 Mar;291(6):1199-1219
The FEBS journal 2024 Mar;291(6):1199-1219
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Wang H, Liu J, Zhang Z, Peng J, Wang Z, Yang L, Wang X, Hu S, Hong L
Free radical biology & medicine 2024 Mar;214:137-157
Free radical biology & medicine 2024 Mar;214:137-157
Rescuing Nucleus Pulposus Cells from ROS Toxic Microenvironment via Mitochondria-Targeted Carbon Dot-Supported Prussian Blue to Alleviate Intervertebral Disc Degeneration.
Shi Y, Bu W, Chu D, Lin W, Li K, Huang X, Wang X, Wu Y, Wu S, Li D, Xu Z, Cao Z, Chen H, Wang H
Advanced healthcare materials 2024 Mar;13(8):e2303206
Advanced healthcare materials 2024 Mar;13(8):e2303206
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Hu YW, Wang YH, Yang F, Liu DX, Lu GH, Li ST, Wei ZX, Shen X, Jiang ZD, Zhao YF, Pang Q, Song BY, Shi ZW, Shafique S, Zhou K, Chen XL, Su WM, Jian JW, Tang KQ, Liu TL, Zhu YB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation.
Li Q, Tang M, Zhao S, Yang J, Meng Y, Meng C, Ren L, Hu W
Discover oncology 2024 Mar 6;15(1):66
Discover oncology 2024 Mar 6;15(1):66
Network pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis.
Dong Q, Ren G, Li Y, Hao D
Scientific reports 2024 Mar 26;14(1):7088
Scientific reports 2024 Mar 26;14(1):7088
Exploring the molecular mechanism of Artemisia rupestris L. for the treatment of hepatocellular carcinoma via PI3K/AKT pathway.
Zhang S, Cai X, Khan GJ, Cheng J, He J, Zhai K, Mao Y
Journal of ethnopharmacology 2024 Mar 25;322:117572
Journal of ethnopharmacology 2024 Mar 25;322:117572
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
BI-3231, an enzymatic inhibitor of HSD17B13, reduces lipotoxic effects induced by palmitic acid in murine and human hepatocytes.
Alcober-Boquet L, Kraus N, Huber LS, Vutukuri R, Fuhrmann DC, Stross C, Schaefer L, Scholich K, Zeuzem S, Piiper A, Schulz MH, Trebicka J, Welsch C, Ortiz C
American journal of physiology. Cell physiology 2024 Mar 1;326(3):C880-C892
American journal of physiology. Cell physiology 2024 Mar 1;326(3):C880-C892
Dimethyl α-Ketoglutarate Promotes the Synthesis of Collagen and Inhibits Metalloproteinases in HaCaT Cells.
Yu BY, Eom DH, Kim HW, Jeong YJ, Keum YS
Biomolecules & therapeutics 2024 Mar 1;32(2):240-248
Biomolecules & therapeutics 2024 Mar 1;32(2):240-248
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Ci M, Zhao G, Li C, Liu R, Hu X, Pan J, Shen Y, Zhang G, Li Y, Zhang L, Liang P, Cui H
Cell death & disease 2024 Mar 1;15(3):179
Cell death & disease 2024 Mar 1;15(3):179
ID2 promotes tumor progression and metastasis in thyroid cancer.
Deng Z, Xu M, Ding Z, Kong J, Liu J, Zhang Z, Cao P
Endocrine 2024 Jun;84(3):1051-1063
Endocrine 2024 Jun;84(3):1051-1063
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.
Xu T, Zhao H, Li J, Fang X, Wu H, Hu W
JOR spine 2024 Jun;7(2):e1325
JOR spine 2024 Jun;7(2):e1325
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Lin JJ, Chen R, Yang LY, Gong M, Du MY, Mu SQ, Jiang ZA, Li HH, Yang Y, Wang XH, Wang SF, Liu KX, Cao SH, Wang ZY, Zhao AQ, Yang SY, Li C, Sun SG
Journal of advanced research 2024 Jun;60:93-110
Journal of advanced research 2024 Jun;60:93-110
Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis.
Gu M, Li C, Deng Q, Chen X, Lei R
Phytotherapy research : PTR 2024 Jun;38(6):3020-3036
Phytotherapy research : PTR 2024 Jun;38(6):3020-3036
ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126.
Zhang J, Chen C, Geng Q, Li H, Wu M, Chan B, Wang S, Sheng W
Journal of cellular physiology 2024 Jun;239(6):e31259
Journal of cellular physiology 2024 Jun;239(6):e31259
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4.
Yang C, Xing S, Wei X, Lu J, Zhao G, Ma X, Dai Z, Liang X, Huang W, Liu Y, Jiang X, Zhu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116736
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
Song N, Cui K, Zeng L, Fan Y, Wang Z, Shi P, Su W, Wang H
Journal of proteomics 2024 Jun 15;301:105182
Journal of proteomics 2024 Jun 15;301:105182
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Yang S, Sun Y, Wang N, Yang Z, Xing H, Jia J
Molecular and cellular biochemistry 2024 Jun 15;
Molecular and cellular biochemistry 2024 Jun 15;
Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport.
Liu Y, Han Y, Liu Y, Huang C, Feng W, Cui H, Li M
Journal of ethnopharmacology 2024 Jun 12;327:117946
Journal of ethnopharmacology 2024 Jun 12;327:117946
FLNA overexpression promotes papillary thyroid cancer aggression via the FAK/AKT signaling pathway.
Liang W, Zhang Y, Guo Y, Zhang P, Jin J, Guan H, Li Y
Endocrine connections 2024 Jun 1;13(6)
Endocrine connections 2024 Jun 1;13(6)
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Chen J, Zeng C, Jin J, Zhang P, Zhang Y, Zhang H, Li Y, Guan H
Endocrine 2024 Jul;85(1):238-249
Endocrine 2024 Jul;85(1):238-249
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood-Brain Barrier in vitro.
Huang F, Mao F, Nong W, Gong Z, Lao D, Huang W
Molecular neurobiology 2024 Jul;61(7):4166-4177
Molecular neurobiology 2024 Jul;61(7):4166-4177
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner.
Zhang S, Gu Y, Ge J, Xie Y, Yu X, Wu X, Sun D, Zhang X, Guo J, Guo J
Oncogene 2024 Jul;43(28):2160-2171
Oncogene 2024 Jul;43(28):2160-2171
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Li H, Qin S, Tang J, Wang T, Ren W, Di L, Bo W, Ma Y, Wu F, Xu Z, Song W, Cai M, Xi Y, Tian Z
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Discovery of Novel 2-Oxoacetamide Derivatives as B3GAT3 Inhibitors for the Treatment of Hepatocellular Carcinoma.
Yin H, Zhang M, Gu C, Li Z, Hao C, Wang J, Tian L, Xu K, Hu X, Ming L, Zhang M, Wang Z, Yang Y, Zhang D, Dai B
Journal of medicinal chemistry 2024 Jul 11;67(13):10743-10773
Journal of medicinal chemistry 2024 Jul 11;67(13):10743-10773
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
Xiao S, Wang W, Zhao C, Ren P, Dong L, Zhang H, Ma F, Li X, Bian Y
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
Zeng C, Li H, Liang W, Chen J, Zhang Y, Zhang H, Xiao H, Li Y, Guan H
Endocrine 2024 Jan;83(1):127-141
Endocrine 2024 Jan;83(1):127-141
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
Zheng Y, Yang S, Dai W, Wang J, Bi S, Zhang X, Zheng Z, Sun Y, Wu S, Kong J
International journal of oncology 2024 Jan;64(1)
International journal of oncology 2024 Jan;64(1)
KRT80 expression works as a biomarker and a target for differentiation in gastric cancer.
Shi KH, Xue H, Zhao EH, Xiao LJ, Sun HZ, Zheng HC
Histology and histopathology 2024 Jan;39(1):117-130
Histology and histopathology 2024 Jan;39(1):117-130
IL-21 promoting angiogenesis contributes to the development of psoriasis.
Han D, Li F, Zhao Y, Wang B, Wang J, Liu B, Mou K, Meng L, Zheng Y, Lu S, Zhu W, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23375
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan;38(1):e23375
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Xu Y, Xu L, Xu C, Zhao M, Xu T, Xia L, Wu Y, Cao Y, Han Z
Brain research bulletin 2024 Jan;206:110836
Brain research bulletin 2024 Jan;206:110836
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Integrated transcriptomic and proteomic analysis reveals Guizhi-Fuling Wan inhibiting STAT3-EMT in ovarian cancer progression.
Ma Q, Chen F, Liu Y, Wu K, Bu Z, Qiu C, Neamati N, Lu T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116016
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Xu L, Zhang L, Zhang S, Yang J, Zhu A, Sun J, Kalvakolanu DV, Cong X, Zhang J, Tang J, Guo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Upregulation of miR-20b-5p inhibits trophoblast invasion by blocking autophagy in recurrent miscarriage.
Lin RC, Chao YY, Su MT, Tsai HL, Tsai PY, Wang CY
Cellular signalling 2024 Jan;113:110934
Cellular signalling 2024 Jan;113:110934
Intervention with extracellular matrix metalloproteinase inducer in osteoclasts attenuates periodontitis-induced bone resorption.
Wang Y, Zhang L, Zhang L, Li J, Sheng Z, Du Y, Zuo Z, Yu X
Odontology 2024 Jan;112(1):148-157
Odontology 2024 Jan;112(1):148-157
MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC).
Wu Q, Li X, Yang Y, Huang J, Yao M, Li J, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2024 Jan 8;16(2)
Cancers 2024 Jan 8;16(2)
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Li Z, Shan X, Yang G, Dong L
International immunopharmacology 2024 Jan 25;127:111458
International immunopharmacology 2024 Jan 25;127:111458
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation.
Wu J, Wang W, Yuan F, Zheng J, Zhang W, Guo H, Wang L, Dai C, Han F, Wu X, Gao J
International immunopharmacology 2024 Jan 25;127:111375
International immunopharmacology 2024 Jan 25;127:111375
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging.
Ge Y, Li M, Bai S, Chen C, Zhang S, Cheng J, Wang X
International immunopharmacology 2024 Jan 25;127:111357
International immunopharmacology 2024 Jan 25;127:111357
Bardoxolone methyl breaks the vicious cycle between M1 macrophages and senescent nucleus pulposus cells through the Nrf2/STING/NF-κB pathway.
Wang P, Zhang S, Liu W, Lv X, Wang B, Hu B, Shao Z
International immunopharmacology 2024 Jan 25;127:111262
International immunopharmacology 2024 Jan 25;127:111262
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
Zheng J, Chen T, Wang K, Peng C, Zhao M, Xie Q, Li B, Lin H, Zhao Z, Ji Z, Tang BZ, Liao Y
ACS nano 2024 Jan 23;18(3):2355-2369
ACS nano 2024 Jan 23;18(3):2355-2369
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
Wang Y, Mang X, Li D, Wang Z, Chen Y, Cai Z, Tan F
Redox biology 2024 Feb;69:102991
Redox biology 2024 Feb;69:102991
DUSP22 suppresses tumor progression by directly dephosphorylating AKT in non-small cell lung cancer.
Chen J, Kang G, Lei W, Li J, Wang H, Bi Y, Zhang W, Zhang L, Chai L, Wang P, Li X
Molecular carcinogenesis 2024 Feb;63(2):314-325
Molecular carcinogenesis 2024 Feb;63(2):314-325
Matrix metalloproteinase-9 inhibition prevents aquaporin-4 depolarization-mediated glymphatic dysfunction in Parkinson's disease.
Si X, Dai S, Fang Y, Tang J, Wang Z, Li Y, Song Z, Chen Y, Liu Y, Zhao G, Zhang B, Pu J
Journal of advanced research 2024 Feb;56:125-136
Journal of advanced research 2024 Feb;56:125-136
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
Chi Z, Wang Q, Tong L, Qiu J, Yang F, Guo Q, Li W, Zheng J, Chen Z
Cell biology international 2024 Feb;48(2):174-189
Cell biology international 2024 Feb;48(2):174-189
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Wu X, Zhang F, Mao X, Xu F, Ding X, Sun X, Wang J
Materials today. Bio 2024 Feb;24:100910
Materials today. Bio 2024 Feb;24:100910
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation.
Zhu J, Wei J, Lin Y, Tang Y, Su Z, Li L, Liu B, Cai X
BMC complementary medicine and therapies 2024 Feb 27;24(1):105
BMC complementary medicine and therapies 2024 Feb 27;24(1):105
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Zhou H, Li J, He Y, Xia X, Liu J, Xiong H
Cancer cell international 2024 Feb 24;24(1):85
Cancer cell international 2024 Feb 24;24(1):85
Loureirin A Promotes Cell Differentiation and Suppresses Migration and Invasion of Melanoma Cells via WNT and AKT/mTOR Signaling Pathways.
Xia ZY, Liu L, Kuok CF, Wang XL, Shi D, Ma Q, Cheng XY, Wang GL, Li MJ, Zheng QS, Liu XN, Li DF, Li BH
Biological & pharmaceutical bulletin 2024 Feb 22;47(2):486-498
Biological & pharmaceutical bulletin 2024 Feb 22;47(2):486-498
Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway.
Hu C, Ji F, Lv R, Zhou H, Hou G, Xu T
Free radical biology & medicine 2024 Feb 20;212:433-447
Free radical biology & medicine 2024 Feb 20;212:433-447
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
Ge W, Yuan G, Wang D, Dong L
Scientific reports 2024 Feb 15;14(1):3783
Scientific reports 2024 Feb 15;14(1):3783
Nupr1-mediated vascular smooth muscle cell phenotype transformation involved in methamphetamine induces pulmonary hypertension.
Zhou J, Guo D, Xu ZZ, Liao JS, Li XT, Duan K, Chen SY, Xie WB
Cell biology and toxicology 2024 Feb 13;40(1):13
Cell biology and toxicology 2024 Feb 13;40(1):13
Fluvastatin prevents lung metastasis in triple-negative breast cancer by triggering autophagy via the RhoB/PI3K/mTOR pathway.
Xu WH, Zhang T, Zhou Y, Mao Y
Experimental cell research 2024 Feb 1;435(1):113893
Experimental cell research 2024 Feb 1;435(1):113893
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling.
Du Q, Zhang M, Gao A, He T, Guo M
Cancer biology & therapy 2024 Dec 31;25(1):2302924
Cancer biology & therapy 2024 Dec 31;25(1):2302924
PFKFB3 facilitates cell proliferation and migration in anaplastic thyroid carcinoma via the WNT/β-catenin signaling pathway.
Deng J, Cheng Y, Li H, He X, Yu S, Ma J, Li X, Chen J, Xiao H, Guan H, Li Y
Endocrine 2024 Aug;85(2):737-750
Endocrine 2024 Aug;85(2):737-750
A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis.
Dong Y, Kang H, Peng R, Liu Z, Liao F, Hu SA, Ding W, Wang P, Yang P, Zhu M, Wang S, Wu M, Ye D, Gan X, Li F, Song K
Cell metabolism 2024 Aug 6;36(8):1679-1695.e6
Cell metabolism 2024 Aug 6;36(8):1679-1695.e6
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6.
Cheng Y, Zhang M, Xu R, Fu L, Xue M, Xu C, Tang C, Fang T, Liu X, Sun B, Chen L
Experimental gerontology 2024 Apr;188:112391
Experimental gerontology 2024 Apr;188:112391
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
Li J, Feng C, Pang X, Li X, Dou X, Jiang E, Shang Z
Discover oncology 2024 Apr 8;15(1):109
Discover oncology 2024 Apr 8;15(1):109
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence.
Wei X, Li Y, Jiang T, Luo P, Dai Y, Wang Q, Xu M, Yan J, Li Y, Gao J, Liu L, Zhang C, Liu Y
European journal of pharmacology 2024 Apr 5;968:176397
European journal of pharmacology 2024 Apr 5;968:176397
Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer.
Chen D, Cai B, Zhu Y, Ma Y, Yu X, Xiong J, Shen J, Tie W, Zhang Y, Guo F
Clinical epigenetics 2024 Apr 4;16(1):51
Clinical epigenetics 2024 Apr 4;16(1):51
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
Liang D, Liu L, Qi Y, Nan F, Huang J, Tang S, Tang J, Chen N
Journal of ethnopharmacology 2024 Apr 24;324:117745
Journal of ethnopharmacology 2024 Apr 24;324:117745
The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
Wu M, Huang X, Wu B, Zhu M, Zhu Y, Yu L, Lan T, Liu J
Molecular biology reports 2024 Apr 20;51(1):553
Molecular biology reports 2024 Apr 20;51(1):553
SERPINB5 promotes colorectal cancer invasion and migration by promoting EMT and angiogenesis via the TNF-α/NF-κB pathway.
Liu BX, Xie Y, Zhang J, Zeng S, Li J, Tao Q, Yang J, Chen Y, Zeng C
International immunopharmacology 2024 Apr 20;131:111759
International immunopharmacology 2024 Apr 20;131:111759
The role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression.
Nie F, Zhang J, Tian H, Zhao J, Gong P, Wang H, Wang S, Yang P, Yang C
Cell death & disease 2024 Apr 18;15(4):277
Cell death & disease 2024 Apr 18;15(4):277
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Wang Z, Dong Z, Li Y, Jiao X, Liu Y, Chang H, Gan Y
Biomedicines 2024 Apr 18;12(4)
Biomedicines 2024 Apr 18;12(4)
Activation of the YY1-UGT2B7 Axis Promotes Mammary Estrogen Homeostasis Dysregulation and Exacerbates Breast Tumor Metastasis.
Xu J, Zhou Y, He S, Wang Y, Ma J, Li C, Liu Z, Zhou X
Drug metabolism and disposition: the biological fate of chemicals 2024 Apr 16;52(5):408-421
Drug metabolism and disposition: the biological fate of chemicals 2024 Apr 16;52(5):408-421
Association of GAL-8 promoter methylation levels with coronary plaque inflammation.
Xia B, Lu Y, Liang J, Li F, Peng J, Wang J, Wan C, Ding J, Le C, Dai J, Guo B, Shen Z
International journal of cardiology 2024 Apr 15;401:131782
International journal of cardiology 2024 Apr 15;401:131782
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells.
He NN, Wang JA, Huang D, Sun XL, Ding F, Zhao L, Zhang YX, Li HM, Wu CZ
Chemical & pharmaceutical bulletin 2023;71(11):798-803
Chemical & pharmaceutical bulletin 2023;71(11):798-803
Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation.
Que Z, Luo B, Yu P, Qi D, Shangguan W, Wang P, Liu J, Li Y, Li H, Ke R, Wu E, Tian J
International journal of biological sciences 2023;19(16):5204-5217
International journal of biological sciences 2023;19(16):5204-5217
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
NEK6 Promotes the Progression of Osteosarcoma Through Activating STAT3 Signaling Pathway by Down-Regulation of miR-26a-5p.
Zhu M, Sun Y, Xue H, Wu G, Wang Z, Shi J, Ma J, Gu B, Yan X
International journal of general medicine 2023;16:2831-2848
International journal of general medicine 2023;16:2831-2848
TREM2 as an independent predictor of poor prognosis promotes the migration via the PI3K/AKT axis in prostate cancer.
Gao HT, Yang Z, Sun H, Zhang Y, Wang Z, Liu WY, Wen HZ, Qu CB, Wang XL
American journal of translational research 2023;15(2):779-798
American journal of translational research 2023;15(2):779-798
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
Inhibition of Non-small Cell Lung Cancer by Ferroptosis and Apoptosis Induction through P53 and GSK-3β/Nrf2 Signal Pathways using Qingrehuoxue Formula.
Xu F, Zhang J, Ji L, Cui W, Cui J, Tang Z, Sun N, Zhang G, Guo M, Liu B, Dong J
Journal of Cancer 2023;14(3):336-349
Journal of Cancer 2023;14(3):336-349
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
Li F, Wang L, Wang Y, Shen H, Kou Q, Shen C, Xu X, Zhang Y, Zhang J
Journal of Cancer 2023;14(15):2820-2832
Journal of Cancer 2023;14(15):2820-2832
A Prognostic Model of Angiogenesis and Neutrophil Extracellular Traps Related Genes Manipulating Tumor Microenvironment in Colon Cancer.
Zhang D, Zhao Y, Wang S, Wang X, Sun Y
Journal of Cancer 2023;14(11):2109-2127
Journal of Cancer 2023;14(11):2109-2127
Characterisation of macrophage infiltration and polarisation based on integrated transcriptomic and histological analyses in Primary Sjögren's syndrome.
Zong Y, Yang Y, Zhao J, Li L, Luo D, Hu J, Gao Y, Wei L, Li N, Jiang L
Frontiers in immunology 2023;14:1292146
Frontiers in immunology 2023;14:1292146
Pan-cancer analysis shows that IBSP is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including osteosarcoma.
Pan B, Cheng X, Tan W, Liu R, Wu X, He J, Fan Q, Zhang Y, Cheng J, Deng Y
Frontiers in immunology 2023;14:1188256
Frontiers in immunology 2023;14:1188256
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Pan B, Yue Y, Ding W, Sun L, Xu M, Wang S
Frontiers in immunology 2023;14:1161382
Frontiers in immunology 2023;14:1161382
Diabetes mellitus induces a novel inflammatory network involving cancer progression: Insights from bioinformatic analysis and in vitro validation.
Tan Y, Kang J, Li H, Zhong A, Liu Y, Zhang Z, Huang R, Cheng X, Peng W
Frontiers in immunology 2023;14:1149810
Frontiers in immunology 2023;14:1149810
Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data.
Wang W, Zhao H, Wang S
Frontiers in immunology 2023;14:1099071
Frontiers in immunology 2023;14:1099071
Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury.
Liu J, Li Z, Lao Y, Jin X, Wang Y, Jiang B, He R, Yang S
Frontiers in pharmacology 2023;14:1060464
Frontiers in pharmacology 2023;14:1060464
Circ_0000231 promotes paclitaxel resistance in ovarian cancer by regulating miR-140/RAP1B.
Liu J, Wang H, Xiao S, Zhang S, Qi Y, Wang M
American journal of cancer research 2023;13(3):872-885
American journal of cancer research 2023;13(3):872-885
Crosstalk between septic shock and venous thromboembolism: a bioinformatics and immunoassay analysis.
Li Z, Wang C, Zhang X, Xu X, Wang M, Dong L
Frontiers in cellular and infection microbiology 2023;13:1235269
Frontiers in cellular and infection microbiology 2023;13:1235269
Identifying key transcription factors and immune infiltration in non-small-cell lung cancer using weighted correlation network and Cox regression analyses.
Zhang J, Wang Y, Yuan B, Qin H, Wang Y, Yu H, Teng X, Yang Y, Zou J, Zhang M, Huang W, Wang Y
Frontiers in oncology 2023;13:1112020
Frontiers in oncology 2023;13:1112020
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
Shi S, Zhong J, Peng W, Yin H, Zhong D, Cui H, Sun X
Frontiers in oncology 2023;13:1075716
Frontiers in oncology 2023;13:1075716
TGF-β1 mediates tumor immunosuppression aggravating at the late stage post-high-light-dose photodynamic therapy.
Han L, Huang X, Zhao B, Zhu H, Wang R, Liu S, Lin H, Feng F, Ma X, Liu F, Xue J, Liu W
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):3079-3095
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):3079-3095
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Zhang Y, Zhao X, Guo C, Zhang Y, Zeng F, Yin Q, Li Z, Shao L, Zhou D, Liu L
Neuroscience bulletin 2023 Sep;39(9):1375-1395
Neuroscience bulletin 2023 Sep;39(9):1375-1395
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Li L, Wang H, Pang S, Wang L, Fan Z, Ma C, Yang S, Banda J, Hui Q, Lv F, Fan H, Huang T, Zhang X, Wang X
The Journal of biological chemistry 2023 Sep;299(9):105127
The Journal of biological chemistry 2023 Sep;299(9):105127
MMP9-Responsive Graphene Oxide Quantum Dot-Based Nano-in-Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization.
Huang K, Liu X, Lv Z, Zhang D, Zhou Y, Lin Z, Guo J
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(39):e2207335
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(39):e2207335
Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathway.
Zhang J, Zhuang Z, Guo M, Wu K, Yang Q, Min X, Cui W, Xu F
Journal of traditional and complementary medicine 2023 Sep;13(5):417-429
Journal of traditional and complementary medicine 2023 Sep;13(5):417-429
N-Acetylcysteine-Derived Carbon Dots for Free Radical Scavenging in Intervertebral Disc Degeneration.
Wu S, Shi Y, Jiang L, Bu W, Zhang K, Lin W, Pan C, Xu Z, Du J, Chen H, Wang H
Advanced healthcare materials 2023 Sep;12(24):e2300533
Advanced healthcare materials 2023 Sep;12(24):e2300533
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
Li Y, Hu S, Chen Y, Zhang X, Gao H, Tian J, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
Dendrobium nobile Lindl Polysaccharides Attenuate UVB-induced Photodamage by Regulating Oxidative Stress, Inflammation and MMPs Expression in Mice Model.
Long Y, Wang W, Zhang Y, Zhang S, Li Z, Deng J, Li J
Photochemistry and photobiology 2023 Sep-Oct;99(5):1269-1281
Photochemistry and photobiology 2023 Sep-Oct;99(5):1269-1281
CSNK2A2 promotes hepatocellular carcinoma progression through activation of NF-κB pathway.
Yang S, Peng LR, Yu AQ, Li J
Annals of hepatology 2023 Sep-Oct;28(5):101118
Annals of hepatology 2023 Sep-Oct;28(5):101118
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Zhou W, Cao W, Wang M, Yang K, Zhang X, Liu Y, Zhang P, Zhang Z, Cao G, Chen B, Xiong M
Molecular diversity 2023 Sep 25;
Molecular diversity 2023 Sep 25;
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
TSPAN8 regulates EGFR/AKT pathway to enhance metastasis in gastric cancer.
Zhang L, Xu Y, Cai E, Zheng M, Liu L, Wang Q, Li S
Molecular biology reports 2023 Oct;50(10):7955-7965
Molecular biology reports 2023 Oct;50(10):7955-7965
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Wenjuan T, Yu HU, Man Z, Mingzhi D, Tieming L, Ammar S, Yingzhuan Z, Yanmin Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
Chen WM, Hu QY, Hou W, Chen MW, Chen YH, Tang JC
Oncology letters 2023 Oct;26(4):443
Oncology letters 2023 Oct;26(4):443
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
Yun WJ, Xue H, Yang N, Xiao LJ, Sun HZ, Zheng HC
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.
Tong Z, Shen Y, Yuan Q, Yu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119553
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119553
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
Huang JG, Ren JX, Chen Y, Tian MF, Zhou L, Wen J, Song XS, Wu YL, Yang QH, Jiang PR, Wang JN, Yang Q
Neural regeneration research 2023 Oct;18(10):2208-2218
Neural regeneration research 2023 Oct;18(10):2208-2218
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Li W, Xu L, Cao J, Ge J, Liu X, Liu P, Teng Y, Wang S, Sun Y, Liu M, Tian L
Immunology 2023 Oct;170(2):253-269
Immunology 2023 Oct;170(2):253-269
Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
Lin W, Song Y, Li T, Yan J, Zhang R, Han L, Ba X, Huang Y, Qin K, Chen Z, Wang Y, Tu S, Huang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115394
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115394
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
Dumbuya JS, Chen X, Du J, Li S, Liang L, Xie H, Zeng Q
International immunopharmacology 2023 Oct;123:110758
International immunopharmacology 2023 Oct;123:110758
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
RRAGB-mediated suppression of PI3K/AKT exerts anti-cancer role in glioblastoma.
Li Q, Liu X, Mao J, Liu S, Hou B, Li K, Fang D
Biochemical and biophysical research communications 2023 Oct 8;676:149-157
Biochemical and biophysical research communications 2023 Oct 8;676:149-157
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
Xia W, Chen X, Zhu Z, Chen H, Li B, Wang K, Huang L, Liu Z, Chen Z
Scientific reports 2023 Oct 23;13(1):18076
Scientific reports 2023 Oct 23;13(1):18076
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB
Nature communications 2023 Oct 18;14(1):6582
Nature communications 2023 Oct 18;14(1):6582
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM, Fu H
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Xu L, Jiang H, Xie J, Xu Q, Zhou J, Lu X, Wang M, Dong L, Zuo D
Heliyon 2023 Nov;9(11):e21882
Heliyon 2023 Nov;9(11):e21882
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Hong JW, Yu Y, Wang LS, Li Z, Zhang R, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway.
Zeng J, Wang Y, Zhu M, Wu M, Zhou Y, Wang Q, Xu Y, Lin F, Wang J, Li Y, Liang S, Wang Z, Xie L, Liu X
The FEBS journal 2023 Nov;290(22):5395-5410
The FEBS journal 2023 Nov;290(22):5395-5410
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Ma X, Zhang L, Gao F, Jia W, Li C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115501
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115501
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Ma RF, Liu H, Zhao XC, Shan P, Sun P, Xue JJ, Wei G, Zhang H
Bioorganic chemistry 2023 Nov;140:106803
Bioorganic chemistry 2023 Nov;140:106803
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Xiao C, Sun Y, Fan J, Nguyen W, Chen S, Long Y, Chen W, Zhu A, Liu B
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Sun X, Liu Z, Zhou L, Ma R, Zhang X, Wang T, Fu F, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Wang Y, Wang G, Liu Y, Yang F, Zhang H, Kong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth.
Mi T, Tan X, Wang Z, Zhang Z, Jin L, Wang J, Li M, Wu X, He D
European journal of medical research 2023 Nov 8;28(1):503
European journal of medical research 2023 Nov 8;28(1):503
The Effect of Adipocyte-Secreted Factors in Activating Focal Adhesion Kinase-Mediated Cell Signaling Pathway towards Metastasis in Breast Cancer Cells.
Mubtasim N, Gollahon L
International journal of molecular sciences 2023 Nov 22;24(23)
International journal of molecular sciences 2023 Nov 22;24(23)
A Regulator Role for the ATP-Binding Cassette Subfamily C Member 6 Transporter in HepG2 Cells: Effect on the Dynamics of Cell-Cell and Cell-Matrix Interactions.
Matera I, Miglionico R, Abruzzese V, Marchese G, Ventola GM, Castiglione Morelli MA, Bisaccia F, Ostuni A
International journal of molecular sciences 2023 Nov 16;24(22)
International journal of molecular sciences 2023 Nov 16;24(22)
Aquaporin 9 causes recurrent spontaneous abortion by inhibiting trophoblast cell epithelial-mesenchymal transformation and invasion through the PI3K/AKT pathway†.
Ma N, Liu B, Jin Y, Wang J, Qin W, Zheng F, Qin R, Li J, Hang F, Qin A
Biology of reproduction 2023 Nov 15;109(5):736-748
Biology of reproduction 2023 Nov 15;109(5):736-748
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Wang H, Yang L, Liu R, He H, Zhang M, Xu Y
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Wang Y, Mang X, Li D, Chen Y, Cai Z, Tan F
Free radical biology & medicine 2023 Nov 1;208:134-152
Free radical biology & medicine 2023 Nov 1;208:134-152
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
NONHSAG028908.3 sponges miR‑34a‑5p to promote growth of colorectal cancer via targeting ALDOA.
Wang C, Xin H, Yan G, Liu Z
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma.
Zhang C, Wang R, Li M, Yang Q
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Wang T, Huang X, Liu J, Liu W, Yang Z, He K, Chen J, Zhao L
Environmental toxicology 2023 May;38(5):1143-1152
Environmental toxicology 2023 May;38(5):1143-1152
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Wu Y, Wang Z, Li S, Chen X, Zhou S
Experimental and therapeutic medicine 2023 May;25(5):195
Experimental and therapeutic medicine 2023 May;25(5):195
Cadmium exposure induces histological damage and cytotoxicity in the cardiovascular system of mice.
Chou SH, Lin HC, Chen SW, Tai YT, Jung SM, Ko FH, Pang JS, Chu PH
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113740
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Chen Y, Ou Z, Pang M, Tao Z, Zheng X, Huang Z, Wen D, Li Q, Zhou R, Chen P, Situ B, Sheng C, Huang Y, Yue X, Zheng L, Huang L
Journal of extracellular vesicles 2023 May;12(5):e12328
Journal of extracellular vesicles 2023 May;12(5):e12328
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
Chen H, Cai X, Du B, Cai J, Luo Z
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression.
Mei J, Liu Y, Sheng Y, Liu Y, Chen L, Wang H, Cheng M, Zhai Z, Xu L
Acta biochimica et biophysica Sinica 2023 May 8;55(5):769-782
Acta biochimica et biophysica Sinica 2023 May 8;55(5):769-782
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Li N, Ye Y, Wu Y, Li L, Hu J, Luo D, Li Y, Yang J, Gao Y, Hai W, Xie Y, Jiang L
iScience 2023 May 19;26(5):106571
iScience 2023 May 19;26(5):106571
Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy.
Li Z, Zhu H, Liu H, Liu D, Liu J, Jiang J, Zhang Y, Qin Z, Xu Y, Peng Y, Liu B, Long Y
Journal of nanobiotechnology 2023 May 19;21(1):158
Journal of nanobiotechnology 2023 May 19;21(1):158
Aristolocholic acid I promotes renal tubular epithelial fibrosis by upregulating matrix metalloproteinase-9 expression via activating the C3a/C3aR axis of macrophages.
Zhang Q, Ye J, Zhang Z, Hu Y, Wang X, Jiang W, Guo X, Chen L, Cheng S, Li J, Zhang L
Toxicology letters 2023 May 15;381:27-35
Toxicology letters 2023 May 15;381:27-35
Toxicity mechanism of peri-implantation pesticide beta-cypermethrin exposure on endometrial remodeling in early pregnant mice.
Zhou YJ, Qiao QF, Wang LQ, Sheng TY, Cui MX, Chen QD, Wang CY, Zhang YX
Toxicology 2023 May 1;489:153497
Toxicology 2023 May 1;489:153497
A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer.
Zhao MN, Zhang LF, Sun Z, Qiao LH, Yang T, Ren YZ, Zhang XZ, Wu L, Qian WL, Guo QM, Xu WX, Wang XQ, Wu F, Wang L, Gu Y, Liu MF, Lou JT
Cell death & disease 2023 May 1;14(5):298
Cell death & disease 2023 May 1;14(5):298
LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.
Han S, Jin X, Hu T, Chi F
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Lu R, Xu H, Deng X, Wang Y, He Z, Xu S, Liang S, Huang X, You H, Guo F, Cheng P, Chen AM
Journal of orthopaedic translation 2023 Mar;39:74-87
Journal of orthopaedic translation 2023 Mar;39:74-87
Improving ocular bioavailability of hydrophilic drugs through dynamic covalent complexation.
Wang JJ, Liu XX, Zhu CC, Wang TZ, Wang SY, Liu Y, Pan XY, Liu MH, Chen D, Li LL, Zhou ZM, Nan KH
Journal of controlled release : official journal of the Controlled Release Society 2023 Mar;355:395-405
Journal of controlled release : official journal of the Controlled Release Society 2023 Mar;355:395-405
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
Meng Q, Bi Y, Feng H, Ding X, Zhang S, Chen Q, Wang L, Zhang Q, Li Y, Tong H, Wu L, Bian H
International immunopharmacology 2023 Mar;116:109825
International immunopharmacology 2023 Mar;116:109825
Sinomenine promotes flap survival by upregulating eNOS and eNOS-mediated autophagy via PI3K/AKT pathway.
Zhang D, Jin C, Han T, Chen J, Ali Raza M, Li B, Wang L, Yan H
International immunopharmacology 2023 Mar;116:109752
International immunopharmacology 2023 Mar;116:109752
Exploring the mechanism of Xingpi Capsule in diarrhea predominant-irritable bowel syndrome treatment based on multiomics technology.
Qian W, Li W, Chen X, Cui L, Liu X, Yao J, Wang X, Liu Y, Li C, Wang Y, Wang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154653
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154653
Fibroblast-Derived Extracellular Vesicle-Packaged Long Noncoding RNA Upregulated in Diabetic Skin Enhances Keratinocyte MMP-9 Expression and Delays Diabetic Wound Healing.
Wu Y, Wu X, Wang J, Chen S, Chen H, Liu J, Zeng T, Hu M, Liang Y, Sun K, Yang C, Yan L, Ren M
Laboratory investigation; a journal of technical methods and pathology 2023 Mar;103(3):100019
Laboratory investigation; a journal of technical methods and pathology 2023 Mar;103(3):100019
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Zhang M, Li L, Li S, Liu Z, Zhang N, Sun B, Wang Z, Jia D, Liu M, Wang Q
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Chen Y, Yang P, Wang J, Gao S, Xiao S, Zhang W, Zhu M, Wang Y, Ke X, Jing H
Experimental hematology & oncology 2023 Mar 7;12(1):28
Experimental hematology & oncology 2023 Mar 7;12(1):28
Ceramide Synthase 1 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Interacting with USP14 and Downregulating the PI3K/AKT/mTOR Signaling Pathway.
Xu Y, Pan J, Lin Y, Wu Y, Chen Y, Li H
Cancers 2023 Mar 27;15(7)
Cancers 2023 Mar 27;15(7)
[DTX2 overexpression promotes migration and invasion of colorectal cancer cells through the Notch2/Akt axis].
Ma Z, Zhao X, Zhang X, Xu G, Liu F
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):340-348
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):340-348
Rab32 promotes glioblastoma migration and invasion via regulation of ERK/Drp1-mediated mitochondrial fission.
Chen P, Lu Y, He B, Xie T, Yan C, Liu T, Wu S, Yeh Y, Li Z, Huang W, Zhang X
Cell death & disease 2023 Mar 15;14(3):198
Cell death & disease 2023 Mar 15;14(3):198
Integrated miRNA and mRNA omics reveal dioscin suppresses migration and invasion via MEK/ERK and JNK signaling pathways in human endometrial carcinoma in vivo and in vitro.
Li XL, Zhang XX, Ma RH, Ni ZJ, Thakur K, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Journal of ethnopharmacology 2023 Mar 1;303:116027
Journal of ethnopharmacology 2023 Mar 1;303:116027
Reduced inhibitory and excitatory input onto parvalbumin interneurons mediated by perineuronal net might contribute to cognitive impairments in a mouse model of sepsis-associated encephalopathy.
Zhang L, Gao YZ, Zhao CJ, Xia JY, Yang JJ, Ji MH
Neuropharmacology 2023 Mar 1;225:109382
Neuropharmacology 2023 Mar 1;225:109382
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Dong M, Luo Y, Lan Y, He Q, Xu L, Pei Z
Heliyon 2023 Jun;9(6):e17613
Heliyon 2023 Jun;9(6):e17613
Albumin fusion with human lactoferrin shows enhanced inhibition of cancer cell migration.
Nopia H, Kurimoto D, Sato A
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2023 Jun;36(3):629-638
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2023 Jun;36(3):629-638
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
Zeng C, Wu JK, Lu X
International journal of experimental pathology 2023 Jun;104(3):140-150
International journal of experimental pathology 2023 Jun;104(3):140-150
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Wu B, Shi L, Wu Y
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2.
Li H, Ouyang J, Liu R
European journal of pharmacology 2023 Jun 5;948:175697
European journal of pharmacology 2023 Jun 5;948:175697
m(6)A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma.
Zhu X, Wu X, Yang H, Xu Q, Zhang M, Liu X, Lv K
Biology direct 2023 Jun 3;18(1):27
Biology direct 2023 Jun 3;18(1):27
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
Tanshinone IIA suppresses burning incense-induced oxidative stress and inflammatory pathways in astrocytes.
Chi MC, Lin ZC, Lee CW, Huang CC, Peng KT, Lin CM, Lee HC, Fang ML, Chiang YC
Ecotoxicology and environmental safety 2023 Jun 15;258:114987
Ecotoxicology and environmental safety 2023 Jun 15;258:114987
Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways.
Liu Q, Liu Y, Li X, Wang D, Zhang A, Pang J, He J, Chen X, Tang NJ
Ecotoxicology and environmental safety 2023 Jun 15;258:114980
Ecotoxicology and environmental safety 2023 Jun 15;258:114980
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway.
Zhao Y, Hu F, Wang Q
Heliyon 2023 Jul;9(7):e18289
Heliyon 2023 Jul;9(7):e18289
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Zheng Y, Sang M, Liu F, Gu L, Li J, Wu Y, Shan B
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Zhang RB, Dong LC, Huang Q, Shen Y, Li HY, Yu SG, Wu QF
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
Chen R, Zhang Y, Zhang H, Zhou H, Tong W, Wu Y, Ma M, Chen Y
European journal of pharmacology 2023 Jul 5;950:175729
European journal of pharmacology 2023 Jul 5;950:175729
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
Wu J, Zhang L, Li W, Wang L, Jia Q, Shi F, Li K, Liao L, Shi Y, Wu S
Scientific reports 2023 Jul 5;13(1):10906
Scientific reports 2023 Jul 5;13(1):10906
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO.
Kuang X, Zhang Z, Li D, Bao W, Pan J, Zhou P, Chen H, Gao Z, Xie X, Yang C, Zhu G, Zhou Z, Tang R, Feng Z, Zhou L, Feng X, Wang L, Yang J, Jiang L
Cellular & molecular biology letters 2023 Jul 31;28(1):62
Cellular & molecular biology letters 2023 Jul 31;28(1):62
Self-powered enzyme-linked microneedle patch for scar-prevention healing of diabetic wounds.
Zhang X, Wang Z, Jiang H, Zeng H, An N, Liu B, Sun L, Fan Z
Science advances 2023 Jul 14;9(28):eadh1415
Science advances 2023 Jul 14;9(28):eadh1415
Hyperin promotes proliferation, migration, and invasion of HTR-8/SVneo trophoblast cells via activation of JAK1/STAT3 pathway in recurrent spontaneous abortions.
Mu Z, Shen S, Tang L, Liu Y, Zhou Z, Lei L
Heliyon 2023 Jan;9(1):e12958
Heliyon 2023 Jan;9(1):e12958
Mast cell stabilization: new mechanism underlying the therapeutic effect of intense pulsed light on rosacea.
Jiang P, Liu Y, Zhang J, Liu Y, Li M, Tao M, Zhang Y, Tang Z, Liu W, Xu Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jan;72(1):75-88
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jan;72(1):75-88
Aiphanol, a multi-targeting stilbenolignan, potently suppresses mouse lymphangiogenesis and lymphatic metastasis.
Chen SM, Zhao CK, Yao LC, Wang LX, Ma YN, Meng L, Cai SQ, Liu CY, Qu LK, Jia YX, Shou CC
Acta pharmacologica Sinica 2023 Jan;44(1):189-200
Acta pharmacologica Sinica 2023 Jan;44(1):189-200
Cellular-scale sex differences in extracellular matrix remodeling by valvular interstitial cells.
Simon LR, Scott AJ, Figueroa Rios L, Zembles J, Masters KS
Heart and vessels 2023 Jan;38(1):122-130
Heart and vessels 2023 Jan;38(1):122-130
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Wang J, Huang P, Pan X, Xia C, Zhang H, Zhao H, Yuan Z, Liu J, Meng C, Liu F
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Mechanism of action of Daqinjiao decoction in treating cerebral small vessel disease explored using network pharmacology and molecular docking technology.
Wang ZY, Li MZ, Li WJ, Ouyang JF, Gou XJ, Huang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154538
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154538
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Yin W, Fu X, Chang W, Han L, Meng J, Cao A, Ren X, Fan Z, Zhou S
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
Protein kinase D1 promotes the survival of random-pattern skin flaps in rats.
Chen J, Chen H, Muhammad I, Han T, Zhang D, Li B, Zhou X, Zhou F
Biochemical and biophysical research communications 2023 Jan 22;641:67-76
Biochemical and biophysical research communications 2023 Jan 22;641:67-76
Simple Nano-Luciferase-Based Assay for the Rapid and High-Throughput Detection of SARS-CoV-2 3C-Like Protease.
Liu J, Ge C, Zha L, Lin L, Li R
Analytical chemistry 2023 Jan 17;95(2):714-719
Analytical chemistry 2023 Jan 17;95(2):714-719
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Xia Y, Hao L, Li Y, Li Y, Chen J, Li L, Han X, Liu Y, Wang X, Li D
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
A Systemic and Integrated Analysis of p63-Driven Regulatory Networks in Mouse Oral Squamous Cell Carcinoma.
Glathar AR, Oyelakin A, Nayak KB, Sosa J, Romano RA, Sinha S
Cancers 2023 Jan 10;15(2)
Cancers 2023 Jan 10;15(2)
Anti-inflammation and anti-aging mechanisms of mercaptopurine in vivo and in vitro.
Jia H, Vashisth MK, Ge Y, Dai Q, He F, Wang X
Biochemical and biophysical research communications 2023 Jan 1;638:103-111
Biochemical and biophysical research communications 2023 Jan 1;638:103-111
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Wang DN, Ni JJ, Li JH, Gao YQ, Ni FJ, Zhang ZZ, Fang JY, Lu J, Yao YF
PLoS pathogens 2023 Feb;19(2):e1011189
PLoS pathogens 2023 Feb;19(2):e1011189
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Hydrogen attenuates postoperative pain through Trx1/ASK1/MMP9 signaling pathway.
Li J, Ruan S, Jia J, Li Q, Jia R, Wan L, Yang X, Teng P, Peng Q, Shi YD, Yu P, Pan Y, Duan ML, Liu WT, Zhang L, Hu L
Journal of neuroinflammation 2023 Feb 3;20(1):22
Journal of neuroinflammation 2023 Feb 3;20(1):22
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Chen C, Fan P, Zhang L, Xue K, Hu J, Huang J, Lu W, Xu J, Xu S, Qiu G, Ran J, Gan S
Neuroscience 2023 Feb 1;510:95-108
Neuroscience 2023 Feb 1;510:95-108
Silencing of FAM111B inhibited proliferation, migration and invasion of hepatoma cells through activating p53 pathway.
Li F, He HY, Fan ZH, Li CM, Gong Y, Wang XJ, Xiong HJ, Xie CM, Bie P
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Dec;55(12):1679-1689
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Dec;55(12):1679-1689
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives.
Sun X, Chen J, Huang D, Ding F, Zhao L, Li HM, Wang XS, Zhang YX, Wu CZ
Molecular diversity 2023 Dec 8;
Molecular diversity 2023 Dec 8;
LINC01060 knockdown inhibits osteosarcoma cell malignant behaviors in vitro and tumor growth and metastasis in vivo through the PI3K/Akt signaling.
Zhang Q, Tang X, Zhou Y, Chen X, Peng K, Jiang R, Liu Z, Song X, Xia H
Cancer biology & therapy 2023 Dec 31;24(1):2198904
Cancer biology & therapy 2023 Dec 31;24(1):2198904
Tetrahydropalmatine: Orchestrating survival - Regulating autophagy and apoptosis via the PI3K/AKT/mTOR pathway in perforator flaps.
Chen X, Fu K, Lai Y, Dong C, Chen Z, Huang Y, Li G, Jiang R, Wu H, Wang A, Huang S, Shen L, Gao W, Li S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115887
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115887
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J
Nature communications 2023 Dec 20;14(1):8462
Nature communications 2023 Dec 20;14(1):8462
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34.
Wu J, Yue C, Xu W, Li H, Zhu J, Li L
Oncology letters 2023 Aug;26(2):325
Oncology letters 2023 Aug;26(2):325
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
Zhou Y, Zhang T, Wang S, Yang R, Jiao Z, Lu K, Li H, Jiang W, Zhang X
Pharmacological research 2023 Aug;194:106846
Pharmacological research 2023 Aug;194:106846
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Wang F, Yi J, Chen Y, Bai X, Lu C, Feng S, Zhou X
Acta histochemica 2023 Aug;125(6):152071
Acta histochemica 2023 Aug;125(6):152071
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Dai H, Wu R, Zhang J, Dou R, Xu M, Wang J, Wang J, Su F, Zhang T
Cancer medicine 2023 Aug;12(16):17212-17222
Cancer medicine 2023 Aug;12(16):17212-17222
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
LncRNA NEAT1: A novel regulator associated with the inflammatory response in acute respiratory distress syndrome.
Ge S, Hu J, Gao S, Ren J, Zhu G
Gene 2023 Aug 20;878:147582
Gene 2023 Aug 20;878:147582
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Zhou X, Li Y, Yang C, Chen D, Wang T, Liu T, Yan W, Su Z, Peng B, Ren X
Life sciences 2023 Aug 15;327:121698
Life sciences 2023 Aug 15;327:121698
HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function.
Awad-Igbaria Y, Ferreira N, Keadan A, Sakas R, Edelman D, Shamir A, Francous-Soustiel J, Palzur E
Journal of translational medicine 2023 Aug 15;21(1):545
Journal of translational medicine 2023 Aug 15;21(1):545
ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.
Han S, Jin X, Hu T, Chi F
Carcinogenesis 2023 Aug 10;44(5):369-382
Carcinogenesis 2023 Aug 10;44(5):369-382
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
Knockdown of Krüppel-Like Factor 9 Inhibits Aberrant Retinal Angiogenesis and Mitigates Proliferative Diabetic Retinopathy.
Han N, Zhang L, Guo M, Yu L
Molecular biotechnology 2023 Apr;65(4):612-623
Molecular biotechnology 2023 Apr;65(4):612-623
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678
Inflammation 2023 Apr;46(2):655-678
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell.
Zhou W, Ma J, Zhao H, Wang Q, Guo X, Chen L, Cao Z, Xu J, Zhang B, Zhou X
Molecular & cellular proteomics : MCP 2023 Apr;22(4):100520
Molecular & cellular proteomics : MCP 2023 Apr;22(4):100520
Circular RNA circ0104103 inhibits colorectal cancer progression through interactions with HuR and miR-373-5p.
Tan P, Sun H, Xu M, Liu X, Qin J, Nie J, Qin X, Wang S, Pan Y
Cancer science 2023 Apr;114(4):1396-1409
Cancer science 2023 Apr;114(4):1396-1409
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Wu T, Zhang X, Liu X, Cai X, Shen T, Pan D, Liang R, Ding R, Hu R, Dong J, Li F, Li J, Xie L, Wang C, Geng S, Yang Z, Xing L, Li Y
BMC medicine 2023 Apr 27;21(1):161
BMC medicine 2023 Apr 27;21(1):161
Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation.
Jiang Y, Zhang M, Wang L, Zhang L, Ma M, Jing M, Li J, Song R, Zhang Y, Yang Z, Zhang Y, Pu Y, Qu X, Fan J
BMC complementary medicine and therapies 2023 Apr 17;23(1):122
BMC complementary medicine and therapies 2023 Apr 17;23(1):122
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Zhang ZF, Liu F, Zhang HR, Liu B, Zheng SQ, Ye WQ, Ding JN, Zhou ZJ, Luo HX, Wu F, Guo XM, Zhou JY, Guo YH
Discover oncology 2023 Apr 13;14(1):43
Discover oncology 2023 Apr 13;14(1):43
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Zhu JX, Tang QQ, Zhou C, Shi XC, Yi SY, Yang Y
Frontiers in cardiovascular medicine 2022;9:808732
Frontiers in cardiovascular medicine 2022;9:808732
Effects of limonin treatment on the survival of random skin flaps in mice.
Zhang T, Huang Q, Gan K, Zhou K, Hu K, Ding W, Jin J, Li J
Frontiers in surgery 2022;9:1043239
Frontiers in surgery 2022;9:1043239
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Lyu L, Cai Y, Zhang G, Jing Z, Liang J, Zhang R, Dang X, Zhang C
Frontiers in molecular biosciences 2022;9:1008802
Frontiers in molecular biosciences 2022;9:1008802
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells.
Li Y, Feng J, Bian Y, Cheng W, Qiao C
Folia histochemica et cytobiologica 2022;60(1):31-43
Folia histochemica et cytobiologica 2022;60(1):31-43
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Chen X, Zhang L, Geng J, Chen Z, Cui X
Journal of oncology 2022;2022:8267891
Journal of oncology 2022;2022:8267891
HMGA1 As a Potential Prognostic and Therapeutic Biomarker in Breast Cancer.
Wang T, Zhou T, Fu F, Han Y, Li Y, Yuan M
Disease markers 2022;2022:7466555
Disease markers 2022;2022:7466555
TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia.
Zhong Y, Zhang Y, Liu W, Zhao Y, Zou L, Liu X
Oxidative medicine and cellular longevity 2022;2022:7202837
Oxidative medicine and cellular longevity 2022;2022:7202837
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
Liu J, Ding D, Liu F, Chen Y
BioMed research international 2022;2022:7184871
BioMed research international 2022;2022:7184871
Guanxinning Tablet Attenuates Coronary Atherosclerosis via Regulating the Gut Microbiota and Their Metabolites in Tibetan Minipigs Induced by a High-Fat Diet.
Yang Q, Xu Y, Shen L, Pan Y, Huang J, Ma Q, Yu C, Chen J, Chen Y, Chen M
Journal of immunology research 2022;2022:7128230
Journal of immunology research 2022;2022:7128230
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
Chen A, Xu M, Chen J, Chen T, Wang Q, Zhang R, Qiu J
BioMed research international 2022;2022:6207701
BioMed research international 2022;2022:6207701
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208
Oxidative medicine and cellular longevity 2022;2022:4295208
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Xu J, Li Y, Li Z, Shao W, Song J, Wei J
Journal of oncology 2022;2022:3966386
Journal of oncology 2022;2022:3966386
IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression.
Chen H, Tang C, Tan C, Wu F, Li Z, Ji W, Lu L, Xu C, Shen Z, Huang Y
Journal of oncology 2022;2022:3445350
Journal of oncology 2022;2022:3445350
Oxymatrine Protects Chondrocytes against IL-1β-triggered Apoptosis in Vitro and Inhibits Osteoarthritis in Mice Model.
Mohetaer D, Cao L, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2745946
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2745946
GLP-1 RA Improves Diabetic Retinopathy by Protecting the Blood-Retinal Barrier through GLP-1R-ROCK-p-MLC Signaling Pathway.
Wei L, Mo W, Lan S, Yang H, Huang Z, Liang X, Li L, Xian J, Xie X, Qin Y, Lin F, Luo Z
Journal of diabetes research 2022;2022:1861940
Journal of diabetes research 2022;2022:1861940
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Xie Y, Tan J, Qin Y, Cao Y, Wang Y, Li A, Wang Z, Qiao Z, Yan Z
International journal of medical sciences 2022;19(3):511-524
International journal of medical sciences 2022;19(3):511-524
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin.
Xiao J, Li Y, Cheng G, Xu G
Open medicine (Warsaw, Poland) 2022;17(1):768-780
Open medicine (Warsaw, Poland) 2022;17(1):768-780
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Qian W, Yang L, Ni Y, Yin F, Qin L, Yang Y
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Open medicine (Warsaw, Poland) 2022;17(1):1357-1367
Gab1 regulates invadopodia and autocrine VEGF through SHP2/ERK1/2 in hilar cholangiocarcinoma cells.
Li T, Tian Y, Ren W, Chen P, Luo M, Sang H
American journal of translational research 2022;14(12):8934-8946
American journal of translational research 2022;14(12):8934-8946
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
Zhao WJ, Fan YP, Ou GY, Qiao XY
Journal of Cancer 2022;13(7):2281-2292
Journal of Cancer 2022;13(7):2281-2292
A novel hypoxia-driven gene signature that can predict the prognosis and drug resistance of gliomas.
Ren P, Wang JY, Zeng ZR, Li NX, Chen HL, Peng XG, Bhawal UK, Guo WZ
Frontiers in genetics 2022;13:976356
Frontiers in genetics 2022;13:976356
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells.
Wu K, Wu X, Liang Y, Wang T, Wu D, Li L, Wang Z
Frontiers in pharmacology 2022;13:922477
Frontiers in pharmacology 2022;13:922477
ABCA12 Promotes Proliferation and Migration and Inhibits Apoptosis of Pancreatic Cancer Cells Through the AKT Signaling Pathway.
Zheng S, Liu D, Wang F, Jin Y, Zhao S, Sun S, Wang S
Frontiers in genetics 2022;13:906326
Frontiers in genetics 2022;13:906326
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Li Y, Deng Y, Zhang X, Fu H, Han X, Guo W, Zhao W, Zhao X, Yu C, Li H, Lei K, Wang T
Frontiers in pharmacology 2022;13:897465
Frontiers in pharmacology 2022;13:897465
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Zhang C, Zhong Z, Sang W, Ghorbani F, Ghalandari B, Mohamadali M, Irani S, Qian Z, Yi C, Yu B
Frontiers in endocrinology 2022;13:885507
Frontiers in endocrinology 2022;13:885507
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss.
Wang T, Mo L, Ou J, Fang Q, Wu H, Wu Y, Nandakumar KS
Frontiers in immunology 2022;13:833040
Frontiers in immunology 2022;13:833040
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Zhang MX, Huang XY, Song Y, Xu WL, Li YL, Li C
Frontiers in pharmacology 2022;13:1103557
Frontiers in pharmacology 2022;13:1103557
Supercritical fluid extract of Angelica sinensis promotes the anti-colorectal cancer effect of oxaliplatin.
Hao D, Liu J, Guo Z, Chen J, Li T, Li X, Mei K, Wang L, Wang X, Wu Q
Frontiers in pharmacology 2022;13:1007623
Frontiers in pharmacology 2022;13:1007623
A multi-targeting natural product, aiphanol, inhibits tumor growth and metastasis.
Chen SM, Feng JN, Zhao CK, Yao LC, Wang LX, Meng L, Cai SQ, Liu CY, Qu LK, Jia YX, Shou CC
American journal of cancer research 2022;12(11):4930-4953
American journal of cancer research 2022;12(11):4930-4953
RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair.
Gou R, Li X, Dong H, Hu Y, Liu O, Liu J, Lin B
Frontiers in oncology 2022;12:936550
Frontiers in oncology 2022;12:936550
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.
Cheng J, Zhang Y, Wan R, Zhou J, Wu X, Fan Q, He J, Tan W, Deng Y
Frontiers in oncology 2022;12:919108
Frontiers in oncology 2022;12:919108
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Li S, Hu Y, Liu O, Li X, Lin B
Frontiers in oncology 2022;12:1034737
Frontiers in oncology 2022;12:1034737
Deficient DNASE1L3 facilitates neutrophil extracellular traps-induced invasion via cyclic GMP-AMP synthase and the non-canonical NF-κB pathway in diabetic hepatocellular carcinoma.
Li N, Zheng X, Chen M, Huang L, Chen L, Huo R, Li X, Huang Y, Sun M, Mai S, Wu Z, Zhang H, Liu J, Yang CT
Clinical & translational immunology 2022;11(4):e1386
Clinical & translational immunology 2022;11(4):e1386
Ectopic Endometrial Cell-Derived Exosomal Moesin Induces Eutopic Endometrial Cell Migration, Enhances Angiogenesis and Cytosolic Inflammation in Lesions Contributes to Endometriosis Progression.
Abudula M, Fan X, Zhang J, Li J, Zhou X, Chen Y
Frontiers in cell and developmental biology 2022;10:824075
Frontiers in cell and developmental biology 2022;10:824075
Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation.
Chen GH, Yang JG, Xia HF, Zhang LZ, Chen YH, Wang KM, Duan X, Wu LZ, Zhao YF, Chen G
Cell and tissue research 2022 Sep;389(3):517-530
Cell and tissue research 2022 Sep;389(3):517-530
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Ma T, Cheng H, Li T, Chen Y, Cai T, Bai J, Wu Z, Xia X, Liang T, Du Y, Fu W
Bioorganic chemistry 2022 Sep;126:105899
Bioorganic chemistry 2022 Sep;126:105899
EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.
Zhao W, Liu L, Li X, Xu S
International immunopharmacology 2022 Sep;110:109031
International immunopharmacology 2022 Sep;110:109031
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Chen W, Wang H, Lu Y, Huang Y, Xuan Y, Li X, Guo T, Wang C, Lai D, Wu S, Zhao W, Mai H, Li H, Wang B, Ma X, Zhang X
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome.
Sifat AE, Archie SR, Nozohouri S, Villalba H, Zhang Y, Sharma S, Ghanwatkar Y, Vaidya B, Mara D, Cucullo L, Abbruscato TJ
Fluids and barriers of the CNS 2022 Sep 9;19(1):74
Fluids and barriers of the CNS 2022 Sep 9;19(1):74
Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model.
Lu KW, Lu TJ, Chueh FS, Lai KC, Hsia TC, Peng SF, Cheng CC, Chou YC, Hsu FT
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Tong Q, Yi M, Kong P, Xu L, Huang W, Niu Y, Gan X, Zhan H, Tian R, Yan D
Cancer cell international 2022 Sep 6;22(1):278
Cancer cell international 2022 Sep 6;22(1):278
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
Dahlke E, Engmann T, Anan Y, Häsler R, Solinas G, Theilig F
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Tian B, Li X, Zhang J, Zhang M, Gan D, Deng D, Sun L, He X, Wu C, Chen F
International journal of oral science 2022 Sep 5;14(1):45
International journal of oral science 2022 Sep 5;14(1):45
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
Feng D, Zhou J, Liu H, Wu X, Li F, Zhao J, Zhang Y, Wang L, Chao M, Wang Q, Qin H, Ge S, Liu Q, Zhang J, Qu Y
Science advances 2022 Sep 30;8(39):eabq2423
Science advances 2022 Sep 30;8(39):eabq2423
Design, Synthesis, and Biological Evaluation of Dual-Target COX-2/CYP51 Inhibitors for the Treatment of Fungal Infectious Diseases.
Liu W, Liu Y, Fan H, Liu M, Han J, An Y, Dong Y, Sun B
Journal of medicinal chemistry 2022 Sep 22;65(18):12219-12239
Journal of medicinal chemistry 2022 Sep 22;65(18):12219-12239
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Wang Y, Gao H, Huang X, Chen Z, Kang P, Zhou Y, Qin D, Zhang W, Liu J
Carbohydrate polymers 2022 Sep 15;292:119632
Carbohydrate polymers 2022 Sep 15;292:119632
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Liu Y, Wang J, Chen J, Wu S, Zeng X, Xiong Q, Guo Y, Sun J, Song F, Xu J, Yuan S, Li C, He Y, Wang M, Chen L, Shi YB, Guo M, Guo D, Sun G
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Xiao ZN, Guo DY, Yang J
Biology of reproduction 2022 Sep 12;107(3):834-845
Biology of reproduction 2022 Sep 12;107(3):834-845
A Novel lncRNA Mediates the Delayed Tooth Eruption of Cleidocranial Dysplasia.
Xin Y, Liu Y, Li J, Liu D, Zhang C, Wang Y, Zheng S
Cells 2022 Sep 1;11(17)
Cells 2022 Sep 1;11(17)
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Mehmood A, Althobaiti F, Zhao L, Usman M, Chen X, Alharthi F, Soliman MM, Shah AA, Murtaza MA, Nadeem M, Ranjha MMAN, Wang C
Journal of food biochemistry 2022 Oct;46(10):e14286
Journal of food biochemistry 2022 Oct;46(10):e14286
Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development.
Tossetta G, Fantone S, Busilacchi EM, Di Simone N, Giannubilo SR, Scambia G, Giordano A, Marzioni D
Cell and tissue research 2022 Oct;390(1):113-129
Cell and tissue research 2022 Oct;390(1):113-129
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Chen S, Li QH, Chen X, Bao HJ, Wu W, Shen F, Lu BF, Jiang RQ, Zong ZH, Zhao Y
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
Journal of cellular and molecular medicine 2022 Oct;26(20):5150-5164
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Hong C, Lin J
Cancer science 2022 Oct;113(10):3593-3607
Cancer science 2022 Oct;113(10):3593-3607
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q
International immunopharmacology 2022 Oct;111:109129
International immunopharmacology 2022 Oct;111:109129
LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway.
Sun XY, Li HZ, Xie DF, Gao SS, Huang X, Guan H, Bai CJ, Zhou PK
Journal of translational medicine 2022 Oct 5;20(1):456
Journal of translational medicine 2022 Oct 5;20(1):456
Belinostat (PXD101) resists UVB irradiation-induced cellular senescence and skin photoaging.
Jia HJ, Ge Y, Xia J, Shi YL, Wang XB
Biochemical and biophysical research communications 2022 Oct 30;627:122-129
Biochemical and biophysical research communications 2022 Oct 30;627:122-129
Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma.
Chen S, Chen X, Zhang P, Chen S, Wang X, Luo Q, Cui Z, Huang Y, Wan L, Hou X, Yao H, Liu X, He A, Jiang Z, Qiu J, Li Y, Yu K, Zhuang J
Investigative ophthalmology & visual science 2022 Oct 3;63(11):28
Investigative ophthalmology & visual science 2022 Oct 3;63(11):28
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Liu Z, Liu R, Wang R, Dai J, Chen H, Wang J, Li X
Food & function 2022 Oct 3;13(19):9973-9987
Food & function 2022 Oct 3;13(19):9973-9987
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
Lv S, Zhang Y, Song J, Chen J, Huang B, Luo Y, Zhao Y
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Feng Y, Zhu G, Chen R, Shi G, Peng M, Zhou Y, Fu W, Zhou P
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Multipronged Micelles-Hydrogel for Targeted and Prolonged Drug Delivery in Chronic Wound Infections.
Zhao Q, Liu J, Liu S, Han J, Chen Y, Shen J, Zhu K, Ma X
ACS applied materials & interfaces 2022 Oct 19;14(41):46224-46238
ACS applied materials & interfaces 2022 Oct 19;14(41):46224-46238
KLK12 Regulates MMP-1 and MMP-9 via Bradykinin Receptors: Biomarkers for Differentiating Latent and Active Bovine Tuberculosis.
Wang Y, Qu M, Liu Y, Wang H, Dong Y, Zhou X
International journal of molecular sciences 2022 Oct 14;23(20)
International journal of molecular sciences 2022 Oct 14;23(20)
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Synergistic anti-inflammatory effect of gut microbiota and lithocholic acid on liver fibrosis.
Shao J, Ge T, Tang C, Wang G, Pang L, Chen Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1389-1401
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1389-1401
STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer.
Yu S, E C, Yang J
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Nov;22(7):1003-1012
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Nov;22(7):1003-1012
Analysis of meat color, meat tenderness and fatty acid composition of meat in second filial hybrid offspring of MSTN mutant pigs.
Gao K, Luo Z, Han S, Li Z, Choe HM, Paek HJ, Quan B, Kang J, Yin X
Meat science 2022 Nov;193:108929
Meat science 2022 Nov;193:108929
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Yan X, Shang X, Feng Z, Chen B, Wu Y, Zhou Y, Li Y, Zhang L
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.
Lin L, Gao Y, Hu X, Ouyang J, Liu C
BMC women's health 2022 Nov 24;22(1):470
BMC women's health 2022 Nov 24;22(1):470
Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Kuo CH, Wu YF, Chang BI, Hsu CK, Lai CH, Wu HL
Journal of biomedical science 2022 Nov 18;29(1):98
Journal of biomedical science 2022 Nov 18;29(1):98
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Zhang H, Liu J, Dang Q, Wang X, Chen J, Lin X, Yang N, Du J, Shi H, Liu Y, Han J
BMC molecular and cell biology 2022 Nov 16;23(1):48
BMC molecular and cell biology 2022 Nov 16;23(1):48
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Zhou W, Fu Y, Xu JS
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
A novel Granzymes and miRNA nanocapsules co-delivery system for tumor suppression.
Shi Z, Zhao M, Lin T, Chen J, Qian X
Biomedical physics & engineering express 2022 Nov 11;8(6)
Biomedical physics & engineering express 2022 Nov 11;8(6)
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
Role of Wnt/β-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis.
Zou T, Ma L, Gu L, Xi S, Zhang K, Guo X
Chemico-biological interactions 2022 Nov 1;367:110145
Chemico-biological interactions 2022 Nov 1;367:110145
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Qin X, Wang J, Chen S, Liu G, Wu C, Lv Q, He X, Bai X, Huang W, Liao H
Glia 2022 May;70(5):892-912
Glia 2022 May;70(5):892-912
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
Zhang Y, Hui J, Xu Y, Ma Y, Sun Z, Zhang M, Nie L, Ye L
Chemosphere 2022 May;295:133925
Chemosphere 2022 May;295:133925
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1.
Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W
Nature communications 2022 May 5;13(1):2467
Nature communications 2022 May 5;13(1):2467
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
Zhai J, Ma L, Chang Z, Yu T
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
Ren J, Lan T, Liu T, Liu Y, Shao B, Men K, Ma Y, Liang X, Wei YQ, Luo M, Wei XW
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Jiang H, Niu Y, He Y, Li X, Xu Y, Liu X
Journal of cellular physiology 2022 Mar;237(3):1948-1963
Journal of cellular physiology 2022 Mar;237(3):1948-1963
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Xu Y, Shi H, Wang M, Huang P, Xu M, Han S, Li H, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):247
Experimental and therapeutic medicine 2022 Mar;23(3):247
The anti-inflammation effect of strontium ranelate on rat chondrocytes with or without IL-1β in vitro.
Yu H, Liu Y, Yang X, He J, Zhong Q, Guo X
Experimental and therapeutic medicine 2022 Mar;23(3):208
Experimental and therapeutic medicine 2022 Mar;23(3):208
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Kang H, Dong Y, Peng R, Liu H, Guo Q, Song K, Zhu M, Yu K, Wu W, Li F
Biochemical pharmacology 2022 Mar;197:114932
Biochemical pharmacology 2022 Mar;197:114932
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways.
Tu Y, Tan L, Lu T, Wang K, Wang H, Han B, Zhao Y, Chen H, Li Y, Chen H, Chen M, He C
Biochemical pharmacology 2022 Mar;197:114912
Biochemical pharmacology 2022 Mar;197:114912
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury.
Tang W, Guo ZD, Chai WN, Du DL, Yang XM, Cao L, Chen H, Zhou C, Cheng CJ, Sun XC, Huang ZJ, Zhong JJ
Neural regeneration research 2022 Mar;17(3):577-586
Neural regeneration research 2022 Mar;17(3):577-586
Expressions and significances of CTSL, the target of COVID-19 on GBM.
Dong Q, Li Q, Duan L, Wang H, Yan Y, Yin H, Niu L, Zhang H, Wang B, Yuan G, Pan Y
Journal of cancer research and clinical oncology 2022 Mar;148(3):599-608
Journal of cancer research and clinical oncology 2022 Mar;148(3):599-608
Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu).
Gao X, Fan X, Zeng W, Liang J, Guo N, Yang X, Zhao Y
Bioengineered 2022 Mar;13(3):7881-7893
Bioengineered 2022 Mar;13(3):7881-7893
Periodontopathic Bacterium Fusobacterium nucleatum Affects Matrix Metalloproteinase-9 Expression in Human Alveolar Epithelial Cells and Mouse Lung.
Suzuki R, Kamio N, Sugimoto K, Maruoka S, Gon Y, Kaneko T, Yonehara Y, Imai K
In vivo (Athens, Greece) 2022 Mar-Apr;36(2):649-656
In vivo (Athens, Greece) 2022 Mar-Apr;36(2):649-656
The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation.
Wu Y, Teng Y, Zhang C, Pan Y, Zhang Q, Zhu X, Liu N, Su X, Lin J
Journal of nanobiotechnology 2022 Mar 9;20(1):120
Journal of nanobiotechnology 2022 Mar 9;20(1):120
Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production.
Guo Q, Zhao H, Cheng H, Kang H, Dong Y, Peng R, Zhu M, Fang Z, Li F
The Journal of biological chemistry 2022 Mar 4;:101775
The Journal of biological chemistry 2022 Mar 4;:101775
Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway.
Zhang P, Tian L, Bao J, Li S, Li A, Wen Y, Wang J, Jie Y
Investigative ophthalmology & visual science 2022 Mar 2;63(3):29
Investigative ophthalmology & visual science 2022 Mar 2;63(3):29
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.
Yang W, Tan S, Yang L, Chen X, Yang R, Oyang L, Lin J, Xia L, Wu N, Han Y, Tang Y, Su M, Luo X, Yang Y, Huang L, Hu Z, Tao Y, Liu L, Jin Y, Wang H, Liao Q, Zhou Y
Molecular therapy oncolytics 2022 Mar 17;24:612-623
Molecular therapy oncolytics 2022 Mar 17;24:612-623
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Jiang Q, Wang Z, Qi Q, Li J, Xin Y, Qiu J
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Zhu M, Niu J, Jiang J, Dong T, Chen Y, Yang X, Liu P
Life sciences 2022 Mar 15;293:120358
Life sciences 2022 Mar 15;293:120358
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Ferrand N, Fert A, Morichon R, Radosevic-Robin N, Zaoui M, Sabbah M
Cancers 2022 Mar 14;14(6)
Cancers 2022 Mar 14;14(6)
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Environmental toxicology 2022 Jun;37(6):1373-1381
Environmental toxicology 2022 Jun;37(6):1373-1381
Early mobilization in spinal cord injury promotes changes in microglial dynamics and recovery of motor function.
Asano K, Nakamura T, Funakoshi K
IBRO neuroscience reports 2022 Jun;12:366-376
IBRO neuroscience reports 2022 Jun;12:366-376
The molecular mechanism of baicalein repressing progression of gastric cancer mediating miR-7/FAK/AKT signaling pathway.
Qiao D, Xing J, Duan Y, Wang S, Yao G, Zhang S, Jin J, Lin Z, Chen L, Piao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154046
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154046
Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.
Shang H, Niu X, Cui W, Sha Z, Wang C, Huang T, Guo P, Wang X, Gao P, Zhang S, Wei K, Zhu R
Food & function 2022 Jun 6;13(11):6350-6361
Food & function 2022 Jun 6;13(11):6350-6361
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Molecular cancer 2022 Jun 30;21(1):140
Molecular cancer 2022 Jun 30;21(1):140
Coordination of Osteoblastogenesis and Osteoclastogenesis by the Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Matrix To Promote Bone Regeneration.
Wu H, Yin G, Pu X, Wang J, Liao X, Huang Z
ACS applied bio materials 2022 Jun 20;5(6):2913-2927
ACS applied bio materials 2022 Jun 20;5(6):2913-2927
Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway.
Wang D, Zhang Y, Cui L, Yang Q, Wang J
Molecular and cellular endocrinology 2022 Jun 15;550:111647
Molecular and cellular endocrinology 2022 Jun 15;550:111647
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
Chang S, Wen J, Su Y, Ma H
Electrophoresis 2022 Jul;43(13-14):1466-1475
Electrophoresis 2022 Jul;43(13-14):1466-1475
SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling.
Zhou Z, Zhang Z, Chen H, Bao W, Kuang X, Zhou P, Gao Z, Li D, Xie X, Yang C, Chen X, Pan J, Tang R, Feng Z, Zhou L, Wang L, Yang J, Jiang L
British journal of cancer 2022 Jul;127(2):211-222
British journal of cancer 2022 Jul;127(2):211-222
Metabolic Intervention Nanoparticles for Triple-Negative Breast Cancer Therapy via Overcoming FSP1-Mediated Ferroptosis Resistance.
Yang J, Jia Z, Zhang J, Pan X, Wei Y, Ma S, Yang N, Liu Z, Shen Q
Advanced healthcare materials 2022 Jul;11(13):e2102799
Advanced healthcare materials 2022 Jul;11(13):e2102799
Canthin-6-one (CO) from Picrasma quassioides (D.Don) Benn. ameliorates lipopolysaccharide (LPS)-induced astrocyte activation and associated brain endothelial disruption.
Yue Q, Xu Y, Lin L, Hoi MPM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154108
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154108
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Zhu W, Tang H, Cao L, Zhang J, Li J, Ma D, Guo C
Chemical biology & drug design 2022 Jul;100(1):108-120
Chemical biology & drug design 2022 Jul;100(1):108-120
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
Zhuo FF, Guo Q, Zheng YZ, Liu TT, Yang Z, Xu QH, Jiang Y, Liu D, Zeng KW, Tu PF
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Chen J, Duan Z, Liu Y, Fu R, Zhu C
Nutrients 2022 Jul 25;14(15)
Nutrients 2022 Jul 25;14(15)
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Zhao C, Miao J, Sun R, Liang R, Chen W, Gao Y, Wang X, Han S, Zhao W, Lei T, Huang C
Aging 2022 Jul 22;14(14):5878-5894
Aging 2022 Jul 22;14(14):5878-5894
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
Zhang L, Ren CF, Yang Z, Gong LB, Wang C, Feng M, Guan WX
Journal of translational medicine 2022 Jul 21;20(1):327
Journal of translational medicine 2022 Jul 21;20(1):327
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Cai G, Ge Z, Xu Y, Cai L, Sun P, Huang G
Scientific reports 2022 Jul 16;12(1):12208
Scientific reports 2022 Jul 16;12(1):12208
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Zhou X, Wang W, Li Z, Chen L, Wen C, Ruan Q, Xu Z, Liu R, Xu J, Bai Y, Deng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.
Zhou H, You P, Liu H, Fan J, Tong C, Yang A, Jiang Y, Liu B
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:828-843
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:828-843
Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.
Lei Y, He X, Huang H, He Y, Lan J, Yang J, Liu W, Zhang T
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jan;24(1):34-47
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jan;24(1):34-47
Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms.
Fan XZ, Wang YY, Cui ZY, Cheng ZH, Zhang HL, Gamper N, Zhang F, Han M
Free radical biology & medicine 2022 Jan;178:111-124
Free radical biology & medicine 2022 Jan;178:111-124
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m(6)A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
MiR-665 suppresses the progression of diffuse large B cell lymphoma (DLBCL) through targeting LIM and SH3 protein 1 (LASP1).
Wang Y, Guo D, Li B, Wang Y, Wang B, Wang Z, Wang M, Teng Q
Leukemia research 2022 Jan;112:106769
Leukemia research 2022 Jan;112:106769
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Zhang B, Zhu Z, Zhang X, Li F, Ding A
Translational andrology and urology 2022 Jan;11(1):53-66
Translational andrology and urology 2022 Jan;11(1):53-66
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Wu X, Wang Y, Fan X, Xu X, Sun W
Aging 2022 Jan 7;14(1):410-429
Aging 2022 Jan 7;14(1):410-429
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Jin Y, Wang H
Journal of ovarian research 2022 Jan 4;15(1):3
Journal of ovarian research 2022 Jan 4;15(1):3
Salidroside Promotes Sensitization to Doxorubicin in Human Cancer Cells by Affecting the PI3K/Akt/HIF Signal Pathway and Inhibiting the Expression of Tumor-Resistance-Related Proteins.
Zeng Q, Nie X, Li L, Liu HF, Peng YY, Zhou WT, Hu XJ, Xu XY, Chen XL
Journal of natural products 2022 Jan 28;85(1):196-204
Journal of natural products 2022 Jan 28;85(1):196-204
TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer.
Chen Y, Chen D, Qin Y, Qiu C, Zhou Y, Dai M, Li L, Sun Q, Jiang Y
Cell death discovery 2022 Jan 24;8(1):35
Cell death discovery 2022 Jan 24;8(1):35
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A
European journal of pharmacology 2022 Jan 15;915:174601
European journal of pharmacology 2022 Jan 15;915:174601
Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension.
Guo M, Zhang M, Cao X, Fang X, Li K, Qin L, He Y, Zhao J, Xu Y, Liu X, Li X
Respiratory research 2022 Jan 11;23(1):6
Respiratory research 2022 Jan 11;23(1):6
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Fan JH, Xu MM, Zhou LM, Gui ZW, Huang L, Li XG, Ye XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
MiR-597-5p suppresses the progression of hepatocellular carcinoma via targeting transcriptional enhancer associate domain transcription factor 1 (TEAD1).
Sun X, Hou Z, Li N, Zhang S
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
In vitro cellular & developmental biology. Animal 2022 Feb;58(2):96-108
Long Noncoding RNA HAND2-AS1 Suppresses Cell Proliferation, Migration, and Invasion of Bladder Cancer via miR-17-5p/KLF9 Axis.
Yang X, Wei X, Yi C, Yang Y, Fang Z, Dai Y, Guo Y, Song D
DNA and cell biology 2022 Feb;41(2):179-189
DNA and cell biology 2022 Feb;41(2):179-189
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Kang H, Guo Q, Dong Y, Peng R, Song K, Wang J, Liu H, Zhu M, Zhao H, Guan H, Li F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Zhuang J, Hao J, Bu F, Yin H, Chen W, Guo H
Pathology, research and practice 2022 Feb;230:153752
Pathology, research and practice 2022 Feb;230:153752
IL-38-mediated NLRP3/caspase-1 inhibition is a disease-modifying treatment for TMJ inflammation.
Luo P, Zhao T, He H
Annals of the New York Academy of Sciences 2022 Feb;1508(1):92-104
Annals of the New York Academy of Sciences 2022 Feb;1508(1):92-104
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.
Yue Q, Zhou X, Zhang Z, Hoi MPM
International journal of molecular sciences 2022 Feb 7;23(3)
International journal of molecular sciences 2022 Feb 7;23(3)
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266
Life sciences 2022 Feb 1;290:120266
PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.
Chen Y, Wang B, Zhao Z, Li M, Wang F
Tissue & cell 2022 Dec;79:101949
Tissue & cell 2022 Dec;79:101949
miR-550a-5p promotes the proliferation and migration of hepatocellular carcinoma by targeting GNE via the Wnt/β-catenin signaling pathway.
Li CM, Wu W, Zhu Z, Lu PL, Gong JP, Ma R
Neoplasma 2022 Dec;69(6):1359-1372
Neoplasma 2022 Dec;69(6):1359-1372
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer.
Lu D, Lin Z, Wang R, Chen Z, Zhuo J, Xu L, Pan L, Li H, Yang X, He C, Shen W, Yang M, Li H, Chen H, Tan W, Wei X, Zheng S, Xu X
Redox biology 2022 Dec;58:102538
Redox biology 2022 Dec;58:102538
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.
Yu J, Qi H, Wang Z, Zhang Z, Song E, Song W, An R
Cell biology international 2022 Dec;46(12):2246-2256
Cell biology international 2022 Dec;46(12):2246-2256
Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO.
Chen H, Chen X, Zhang Z, Bao W, Gao Z, Li D, Xie X, Zhou P, Yang C, Zhou Z, Pan J, Kuang X, Tang R, Feng Z, Zhou L, Zhu D, Yang J, Wang L, Huang H, Tang D, Liu J, Jiang L
Oncogene 2022 Dec;41(49):5253-5265
Oncogene 2022 Dec;41(49):5253-5265
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Wang Y, Ouyang Q, Chang X, Yang M, He J, Tian Y, Sheng J
Drug delivery 2022 Dec;29(1):871-881
Drug delivery 2022 Dec;29(1):871-881
Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment.
Li N, Xie L, Wu Y, Wu Y, Liu Y, Gao Y, Yang J, Zhang X, Jiang L
Materials today. Bio 2022 Dec;16:100360
Materials today. Bio 2022 Dec;16:100360
A yes-associated protein 1- Notch1 receptor positive feedback loop promotes breast cancer lung metastasis by attenuating the bone morphogenetic protein 4-SMAD family member 1/5 signaling.
Zhao L, Lei J, Gu S, Zhang Y, Jing X, Wang L, Zhang L, Ning Q, Luo M, Qi Y, Zhao X, Shao S
Carcinogenesis 2022 Dec 31;43(12):1162-1175
Carcinogenesis 2022 Dec 31;43(12):1162-1175
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Yang Y, Li Y, Yang Q, Liu Z, Chang X, Yang H, Liu J, Li Z, Zuo D
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Ovarian tissue transplantation ameliorates osteoporosis and dyslipidaemia in ovariectomised mice.
Zhou E, Xiang D, Yu B, Yao H, Sun C, Wang Y
Journal of ovarian research 2022 Dec 28;15(1):139
Journal of ovarian research 2022 Dec 28;15(1):139
Multi-specific niflumic acid platinum(IV) complexes displaying potent antitumor activities by improving immunity and suppressing angiogenesis besides causing DNA damage.
Li L, Zhang M, Jia D, Liu Z, Zhang N, Sun B, Wang Z, Liu M, Wang Q
Dalton transactions (Cambridge, England : 2003) 2022 Dec 20;52(1):147-158
Dalton transactions (Cambridge, England : 2003) 2022 Dec 20;52(1):147-158
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
Titania-Nanotube-Coated Titanium Substrates Promote Osteogenesis and Suppress Osteoclastogenesis via Integrin ανβ3.
Kang H, Dong Y, Liu H, Luo C, Song H, Zhu M, Guo Q, Peng R, Li F, Li Y
ACS applied bio materials 2022 Dec 19;5(12):5832-5843
ACS applied bio materials 2022 Dec 19;5(12):5832-5843
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Su SB, Tao L, Liang XL, Chen W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Zhang B, Liu ZY, Wu R, Zhang CM, Cao K, Shan WG, Liu Z, Ji M, Tian ZL, Sethi G, Shi HL, Wang RH
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Acta pharmacologica Sinica 2022 Aug;43(8):2109-2118
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Zhang Y, Cao L, Xie Y, Wang C, Liu X, Zhang X, Chen J
Experimental and therapeutic medicine 2022 Aug;24(2):490
Experimental and therapeutic medicine 2022 Aug;24(2):490
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Macrophage Nuclear Receptor Corepressor 1 Deficiency Protects Against Ischemic Stroke in Mice.
Shao S, Chen YL, Du LJ, Liu Y, Zhu H, Zhou LJ, Liu T, Lin WZ, Yu F, Ma XX, Shi XR, Meng XQ, Liu Y, Wang YL, Bai L, Zhang XH, Jia F, Duan SZ
Journal of cardiovascular translational research 2022 Aug;15(4):816-827
Journal of cardiovascular translational research 2022 Aug;15(4):816-827
Glycometabolic reprogramming-mediated proangiogenic phenotype enhancement of cancer-associated fibroblasts in oral squamous cell carcinoma: role of PGC-1α/PFKFB3 axis.
Li X, Jiang E, Zhao H, Chen Y, Xu Y, Feng C, Li J, Shang Z
British journal of cancer 2022 Aug;127(3):449-461
British journal of cancer 2022 Aug;127(3):449-461
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.
Lu Y, Yang A, Quan C, Pan Y, Zhang H, Li Y, Gao C, Lu H, Wang X, Cao P, Chen H, Lu S, Zhou G
Nature communications 2022 Aug 6;13(1):4594
Nature communications 2022 Aug 6;13(1):4594
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Jia X, Xin M, Xu J, Xiang X, Li X, Jiao Y, Wang L, Jiang J, Pang F, Zhang X, Zhang J
Cell death & disease 2022 Aug 30;13(8):750
Cell death & disease 2022 Aug 30;13(8):750
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.
Wu YL, Zhang CH, Teng Y, Pan Y, Liu NC, Liu PX, Zhu X, Su XL, Lin J
Military Medical Research 2022 Aug 23;9(1):46
Military Medical Research 2022 Aug 23;9(1):46
Development of a series of flurbiprofen and zaltoprofen platinum(IV) complexes with anti-metastasis competence targeting COX-2, PD-L1 and DNA.
Li Z, Li L, Zhao W, Sun B, Liu Z, Liu M, Han J, Wang Z, Li D, Wang Q
Dalton transactions (Cambridge, England : 2003) 2022 Aug 23;51(33):12604-12619
Dalton transactions (Cambridge, England : 2003) 2022 Aug 23;51(33):12604-12619
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Ke S, Liu Z, Wang Q, Zhai G, Shao H, Yu X, Guo J
Cancers 2022 Aug 13;14(16)
Cancers 2022 Aug 13;14(16)
SEZ6L2, regulated by USF1, accelerates the growth and metastasis of breast cancer.
Chen L, Han S, Li Y, Zheng Y, Zhang Q
Experimental cell research 2022 Aug 1;417(1):113194
Experimental cell research 2022 Aug 1;417(1):113194
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
Zhu Q, Wan NB, Deng HW, Lu LL, Zhang Y, He X, Liu H, He Y
Experimental cell research 2022 Aug 1;417(1):113161
Experimental cell research 2022 Aug 1;417(1):113161
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.
Ruan Y, Xu H, Ji X
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Clinical and experimental pharmacology & physiology 2022 Apr;49(4):525-535
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Hu W, Cai C, Li Y, Kang F, Chu T, Dong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Chi Y, Wang F, Zhang Y, Shan Z, Tao W, Lian Y, Xin D, Fan Q, Sun Y
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9.
Wang C, Wang Y, Liu C, Meng X, Hang Z
Bioengineered 2022 Apr;13(4):9495-9507
Bioengineered 2022 Apr;13(4):9495-9507
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Zhu W, Tang H, Li J, Guedes RM, Cao L, Guo C
Bioengineered 2022 Apr;13(4):9233-9247
Bioengineered 2022 Apr;13(4):9233-9247
miR-340-5p affects oral squamous cell carcinoma (OSCC) cells proliferation and invasion by targeting endoplasmic reticulum stress proteins.
Ou D, Wu Y, Zhang J, Liu J, Liu Z, Shao M, Guo X, Cui S
European journal of pharmacology 2022 Apr 5;920:174820
European journal of pharmacology 2022 Apr 5;920:174820
LINC00022 acts as an oncogene in colorectal cancer progression via sponging miR-375-3p to regulate FOXF1 expression.
Xu L, He H, Shang Y, Qu X, Sun J
BMC cancer 2022 Apr 26;22(1):453
BMC cancer 2022 Apr 26;22(1):453
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M
Cell death & disease 2022 Apr 18;13(4):358
Cell death & disease 2022 Apr 18;13(4):358
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer.
Sun J, Ma X, Ying Y, Wang W, Shen H, Wang S, Xie H, Yi J, Zhan W, Li J, Liu B
Cell death discovery 2022 Apr 13;8(1):199
Cell death discovery 2022 Apr 13;8(1):199
A novel promoter-associated non-coding small RNA paGLI1 recruits FUS/P65 to transactivate GLI1 gene expression and promotes infiltrating glioma progression.
Zhong J, Xu M, Su Z, Zhang M, Yu T, Nie L, Gong J, Chen X, Chen N, Zhou Q
Cancer letters 2022 Apr 1;530:68-84
Cancer letters 2022 Apr 1;530:68-84
Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis.
Li X, Cao X, Zhao H, Guo M, Fang X, Li K, Qin L, He Y, Liu X
Frontiers in cell and developmental biology 2021;9:780121
Frontiers in cell and developmental biology 2021;9:780121
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
Wang W, Zhou M, Xu Y, Peng W, Zhang S, Li R, Zhang H, Zhang H, Cheng S, Wang Y, Wei X, Yue C, Yang Q, Chen C
Frontiers in bioengineering and biotechnology 2021;9:762489
Frontiers in bioengineering and biotechnology 2021;9:762489
Sacubitril Ameliorates Cardiac Fibrosis Through Inhibiting TRPM7 Channel.
Jia T, Wang X, Tang Y, Yu W, Li C, Cui S, Zhu J, Meng W, Wang C, Wang Q
Frontiers in cell and developmental biology 2021;9:760035
Frontiers in cell and developmental biology 2021;9:760035
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Xu H, Wei K, Tu J, Chen Y, He Y, Ding Y, Xu H, Bao X, Xie H, Fang H, Wang H
Frontiers in cell and developmental biology 2021;9:741046
Frontiers in cell and developmental biology 2021;9:741046
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Liu H, Zhang Y, Song W, Sun Y, Jiang Y
Frontiers in cell and developmental biology 2021;9:681790
Frontiers in cell and developmental biology 2021;9:681790
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Jin Y, Zhang M, Li M, Zhang H, Zhao L, Qian C, Li S, Zhang H, Gao M, Pan B, Li R, Wan X, Cao C
Frontiers in molecular biosciences 2021;8:725319
Frontiers in molecular biosciences 2021;8:725319
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J
Nutrition and cancer 2021;73(8):1459-1470
Nutrition and cancer 2021;73(8):1459-1470
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Qiao D, Jin J, Xing J, Zhang Y, Jia N, Ren X, Lin Z, Jin N, Chen L, Piao Y
The American journal of Chinese medicine 2021;49(2):525-541
The American journal of Chinese medicine 2021;49(2):525-541
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.
Chen H, Chen B, Li B, Luo X, Wu H, Zhang C, Liu J, Jiang J, Zhao B
Oxidative medicine and cellular longevity 2021;2021:6611668
Oxidative medicine and cellular longevity 2021;2021:6611668
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Zhu X, Hu X, Lou J, Li J, Xu Y, Yu G, Wu C, Ding J, Gao W, Xiao J, Zhou K, Jia C
Oxidative medicine and cellular longevity 2021;2021:6610603
Oxidative medicine and cellular longevity 2021;2021:6610603
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
Guo J, Zhao D, Dong P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
miR-539 Targeting SNAI2 Regulates MMP9 Signaling Pathway and Affects Blood-Brain Barrier Permeability in Cerebrovascular Occlusive Diseases: A Study Based on Head and Neck Ultrasound and CTA.
Li H, Han G, He D, Wang Y, Lin Y, Zhang T, Wang J, Du Y, Li G, Wang Y, Zhou J, Liu B
Journal of healthcare engineering 2021;2021:5699025
Journal of healthcare engineering 2021;2021:5699025
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Yuan C, Bai R, Gao Y, Jiang X, Li S, Sun W, Li Y, Huang Z, Gong Y, Xie C
Oxidative medicine and cellular longevity 2021;2021:4522210
Oxidative medicine and cellular longevity 2021;2021:4522210
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
Chen YQ, Zhu WT, Lin CY, Yuan ZW, Li ZH, Yan PK
International journal of nanomedicine 2021;16:269-281
International journal of nanomedicine 2021;16:269-281
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H
Journal of inflammation research 2021;14:745-760
Journal of inflammation research 2021;14:745-760
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952
OncoTargets and therapy 2021;14:2941-2952
Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC).
Huang GZ, Wu QQ, Zheng ZN, Shao TR, Li F, Lu XY, Ye HY, Chen GX, Song YX, Zeng WS, Ai YL, Lv XZ
OncoTargets and therapy 2021;14:1275-1289
OncoTargets and therapy 2021;14:1275-1289
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Tu Z, Jiang X, Li Y, Yang S, Lin D, Shi Y, Mao C, Zhang X, Lin C
American journal of translational research 2021;13(3):1337-1351
American journal of translational research 2021;13(3):1337-1351
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Zhang B, Zhang Y, Jiang X, Su H, Wang Q, Wudu M, Jiang J, Ren H, Xu Y, Liu Z, Qiu X
Journal of Cancer 2021;12(4):976-987
Journal of Cancer 2021;12(4):976-987
Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway.
Li Z, Huang Y, Xu Y, Wang X, Wang H, Zhao S, Liu H, Yu G, Che X
Journal of Cancer 2021;12(24):7334-7348
Journal of Cancer 2021;12(24):7334-7348
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Yang HL, Xu C, Yang YK, Tang WQ, Hong M, Pan L, Chen HY
Journal of Cancer 2021;12(24):7266-7276
Journal of Cancer 2021;12(24):7266-7276
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Liu O, Wang C, Wang S, Hu Y, Gou R, Dong H, Li S, Li X, Lin B
Journal of Cancer 2021;12(22):6835-6850
Journal of Cancer 2021;12(22):6835-6850
Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells.
Nie X, Gao L, Zheng M, Wang C, Wang S, Li X, Qi Y, Zhu L, Liu J, Lin B
Journal of Cancer 2021;12(19):5772-5788
Journal of Cancer 2021;12(19):5772-5788
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.
Chen L, Yi C, Li W, Tseng Y, Zhang J, Liu J
Journal of Cancer 2021;12(1):89-98
Journal of Cancer 2021;12(1):89-98
Biphasic Effect of Pirfenidone on Angiogenesis.
Gan D, Cheng W, Ke L, Sun AR, Jia Q, Chen J, Xu Z, Xu J, Zhang P
Frontiers in pharmacology 2021;12:804327
Frontiers in pharmacology 2021;12:804327
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Pang J, Wu Y, Peng J, Yang P, Chen L, Jiang Y
Frontiers in neurology 2021;12:726520
Frontiers in neurology 2021;12:726520
Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway.
Pan J, Cao Z, Fang C, Lei Y, Sun J, Huang X, Han D
Frontiers in pharmacology 2021;12:722530
Frontiers in pharmacology 2021;12:722530
Reynoutrin Improves Ischemic Heart Failure in Rats Via Targeting S100A1.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in pharmacology 2021;12:703962
Frontiers in pharmacology 2021;12:703962
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Liu L, Li Q, Yin J, Zhao Z, Sun L, Ran Q, Du X, Wang Y, Li Y, Yang Q, Chen Y, Weng X, Cai W, Zhu X
Frontiers in pharmacology 2021;12:669730
Frontiers in pharmacology 2021;12:669730
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Zhou F, Zhang X, Jiang L, Li S, Chen Y, Wu J
Frontiers in pharmacology 2021;12:667524
Frontiers in pharmacology 2021;12:667524
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Li L, Wei K, Ding Y, Ahati P, Xu H, Fang H, Wang H
Frontiers in immunology 2021;12:666361
Frontiers in immunology 2021;12:666361
Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis.
Gan D, Cheng W, Ke L, Sun AR, Jia Q, Chen J, Lin J, Li J, Xu Z, Zhang P
Frontiers in pharmacology 2021;12:631891
Frontiers in pharmacology 2021;12:631891
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Zhang S, Liu Y, Sun S, Wang J, Li Q, Yan R, Gao Y, Liu H, Liu S, Hao W, Dai H, Liu C, Sun Y, Long W, Mu X, Zhang XD
Theranostics 2021;11(6):2806-2821
Theranostics 2021;11(6):2806-2821
Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer.
Zhu Y, Lam AKY, Shum DKY, Cui D, Zhang J, Yan DD, Li B, Xu WW, Lee NPY, Chan KT, Law S, Tsao SW, Cheung ALM
Theranostics 2021;11(6):2722-2741
Theranostics 2021;11(6):2722-2741
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
Zhu X, Liu S, Yang X, Wang W, Shao W, Ji T
American journal of cancer research 2021;11(2):590-617
American journal of cancer research 2021;11(2):590-617
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
Fan MK, Zhang GC, Chen W, Qi LL, Xie MF, Zhang YY, Wang L, Zhang Q
Frontiers in oncology 2021;11:710689
Frontiers in oncology 2021;11:710689
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, Hu H, Chen T, Tan B
Frontiers in oncology 2021;11:704001
Frontiers in oncology 2021;11:704001
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
Zhao Y, Zhou H, Shen J, Yang S, Deng K, Li Q, Cui W
Frontiers in oncology 2021;11:688882
Frontiers in oncology 2021;11:688882
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
Wang J, Li H, Wang L, Zhang J, Li M, Qiao L, Zhang J, Liu L, Zhang C, Gao J, Li W
Frontiers in oncology 2021;11:681250
Frontiers in oncology 2021;11:681250
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma.
Liu Q, Zhao S, Meng F, Wang H, Sun L, Li G, Gao F, Chen F
Frontiers in oncology 2021;11:661157
Frontiers in oncology 2021;11:661157
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Nisar MA, Zheng Q, Saleem MZ, Ahmmed B, Ramzan MN, Ud Din SR, Tahir N, Liu S, Yan Q
Frontiers in oncology 2021;11:618839
Frontiers in oncology 2021;11:618839
Osteosarcoma Cell-Derived Small Extracellular Vesicles Enhance Osteoclastogenesis and Bone Resorption Through Transferring MicroRNA-19a-3p.
Luo T, Zhou X, Jiang E, Wang L, Ji Y, Shang Z
Frontiers in oncology 2021;11:618662
Frontiers in oncology 2021;11:618662
LncRNA FENDRR in Carcinoma-Associated Fibroblasts Regulates the Angiogenesis of Oral Squamous Cell Carcinoma Through the PI3K/AKT Pathway.
Xu Y, Jiang E, Shao Z, Shang Z
Frontiers in oncology 2021;11:616576
Frontiers in oncology 2021;11:616576
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
Sun J, Chen L, Dong M
Frontiers in oncology 2021;11:616481
Frontiers in oncology 2021;11:616481
Tenascin-C regulates migration of SOX10 tendon stem cells via integrin-α9 for promoting patellar tendon remodeling.
Xu K, Shao Y, Xia Y, Qian Y, Jiang N, Liu X, Yang L, Wang C
BioFactors (Oxford, England) 2021 Sep;47(5):768-777
BioFactors (Oxford, England) 2021 Sep;47(5):768-777
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1.
Ma Y, Xia P, Wang Z, Xu J, Zhang L, Jiang Y
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
Neoplasia (New York, N.Y.) 2021 Sep;23(9):912-928
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Yan L, He Z, Li W, Liu N, Gao S
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Li H, Yang W, Zhang M, He T, Zhou F, G Herman J, Hu L, Guo M
Epigenomics 2021 Sep;13(17):1403-1419
Epigenomics 2021 Sep;13(17):1403-1419
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Zou Y, Pan L, Shen Y, Wang X, Huang C, Wang H, Jin X, Yin C, Wang Y, Jia J, Qian J, Zou Y, Gong H, Ge J
Cell death & disease 2021 Sep 25;12(10):877
Cell death & disease 2021 Sep 25;12(10):877
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
Li N, Yang F, Liu DY, Guo JT, Ge N, Sun SY
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
World journal of gastrointestinal oncology 2021 Sep 15;13(9):1164-1183
TRIM16 overexpression inhibits the metastasis of colorectal cancer through mediating Snail degradation.
Ruan L, Liu W, Yang Y, Chu Z, Yang C, Yang T, Sun J
Experimental cell research 2021 Sep 1;406(1):112735
Experimental cell research 2021 Sep 1;406(1):112735
H(2)S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225
International journal of cardiology 2021 Sep 1;338:215-225
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Inhibition of ACLY Leads to Suppression of Osteoclast Differentiation and Function Via Regulation of Histone Acetylation.
Guo Q, Kang H, Wang J, Dong Y, Peng R, Zhao H, Wu W, Guan H, Li F
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Oct;36(10):2065-2080
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Oct;36(10):2065-2080
Effects of endurance exercise on serum inflammatory cytokine level and kidney structure in a rat diabetes model.
Lin S, Jin S, Zhou F, Hu Y, Zhang M
Experimental and therapeutic medicine 2021 Oct;22(4):1125
Experimental and therapeutic medicine 2021 Oct;22(4):1125
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Guan X, Yu D, HuangFu M, Huang Z, Dou T, Liu Y, Zhou L, Li X, Wang L, Liu H, Wang J, Chen X
Biochemical pharmacology 2021 Oct;192:114742
Biochemical pharmacology 2021 Oct;192:114742
Study on the potential nephrotoxicity and mutagenicity of aristolochic acid IVa and its mechanism.
Xian Z, Tian J, Zhang Y, Meng J, Zhao Y, Li C, Yi Y, Han J, Liu S, Wang L, Pan C, Wang D, Wang F, Liang A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112081
Ultrasmall Prussian blue nanoparticles attenuate UVA-induced cellular senescence in human dermal fibroblasts via inhibiting the ERK/AP-1 pathway.
Li Y, Zeng N, Qin Z, Chen Y, Lu Q, Cheng Y, Xia Q, Lu Z, Gu N, Luo D
Nanoscale 2021 Oct 8;13(38):16104-16112
Nanoscale 2021 Oct 8;13(38):16104-16112
Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90.
Li HM, Ma H, Sun X, Li B, Cao C, Dai Y, Zhu M, Wu CZ
Molecules (Basel, Switzerland) 2021 Oct 30;26(21)
Molecules (Basel, Switzerland) 2021 Oct 30;26(21)
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Liang T, Shen L, Ji Y, Jia L, Dou Y, Guo L
Genes 2021 Oct 21;12(11)
Genes 2021 Oct 21;12(11)
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Liu Y, Wang J, Yang R, Cheng Y, Zhou Y, Li H, Jiang W, Zhang X
Oncogenesis 2021 Oct 14;10(10):69
Oncogenesis 2021 Oct 14;10(10):69
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2.
Fu Y, Wei Y, Zhou Y, Wu H, Hong Y, Long C, Wang J, Wu Y, Wu S, Shen L, Wei G
Endocrinology 2021 Oct 1;162(10)
Endocrinology 2021 Oct 1;162(10)
Circular RNA Paired-Related Homeobox 1 Promotes Gastric Carcinoma Cell Progression via Regulating MicroRNA-665/YWHAZ Axis.
Liu W, Hu W, Hou K, Zhu S
Digestive diseases and sciences 2021 Nov;66(11):3842-3853
Digestive diseases and sciences 2021 Nov;66(11):3842-3853
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway.
He D, Gao J, Zheng L, Liu S, Ye L, Lai H, Pan B, Pan W, Lou C, Chen Z, Fan S
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X, Cui X
Balkan medical journal 2021 Nov;38(6):331-340
Balkan medical journal 2021 Nov;38(6):331-340
Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity.
Wu H, Yin G, Pu X, Wang J, Liao X, Huang Z
Tissue engineering. Part A 2021 Nov;27(21-22):1387-1398
Tissue engineering. Part A 2021 Nov;27(21-22):1387-1398
circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression.
Sun Y, Ma G, Xiang H, Wang X, Wang H, Zhang Y, Qie F, Li C
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Decreased endostatin in db/db retinas is associated with optic disc intravitreal vascularization.
Bonet A, Valença A, Mendes-Jorge L, Casellas A, Rodríguez-Baeza A, Nacher V, Ramos D, Pampalona J, Simó R, Ruberte J
Experimental eye research 2021 Nov;212:108801
Experimental eye research 2021 Nov;212:108801
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy.
Lin B, Liu J, Zhang Y, Wu Y, Chen S, Bai Y, Liu Q, Qin X
BMC genomics 2021 Nov 24;22(1):852
BMC genomics 2021 Nov 24;22(1):852
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction.
Ma Y, Kuang Y, Bo W, Liang Q, Zhu W, Cai M, Tian Z
International journal of molecular sciences 2021 Nov 15;22(22)
International journal of molecular sciences 2021 Nov 15;22(22)
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong L, Ma Y, Wang Z, Liu N, Ma G, Liu C, Shi R, Du G
International immunopharmacology 2021 May;94:107507
International immunopharmacology 2021 May;94:107507
Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.
Cheng XB, Zhang T, Zhu HJ, Ma N, Sun XD, Wang SH, Jiang Y
Neoplasma 2021 May;68(3):546-556
Neoplasma 2021 May;68(3):546-556
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.
Wang X, Zou S, Ren T, Zhao LJ, Yu LF, Li XY, Yan X, Zhang LJ
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Ren K, Li B, Liu Z, Xia L, Zhai M, Wei X, Duan W, Yu S
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment.
Li J, Chen H, Lou J, Bao G, Wu C, Lou Z, Wang X, Ding J, Li Z, Xiao J, Xu H, Gao W, Zhou K
Journal of cellular physiology 2021 May;236(5):3641-3659
Journal of cellular physiology 2021 May;236(5):3641-3659
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Zhang C, Li Q, Qin G, Zhang Y, Li C, Han L, Wang R, Wang S, Chen H, Liu K, He C
Chinese medicine 2021 May 31;16(1):41
Chinese medicine 2021 May 31;16(1):41
Strontium ranelate promotes chondrogenesis through inhibition of the Wnt/β-catenin pathway.
Yu H, Liu Y, Yang X, He J, Zhang F, Zhong Q, Guo X
Stem cell research & therapy 2021 May 20;12(1):296
Stem cell research & therapy 2021 May 20;12(1):296
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.
Weng WT, Kuo PC, Brown DA, Scofield BA, Furnas D, Paraiso HC, Wang PY, Yu IC, Yen JH
Journal of neuroinflammation 2021 May 11;18(1):110
Journal of neuroinflammation 2021 May 11;18(1):110
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
Qin W, Tong X, Liang R, Tang K, Wu X, Jia Y, Tan N
Journal of ethnopharmacology 2021 May 10;271:113827
Journal of ethnopharmacology 2021 May 10;271:113827
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
CHRDL2 promotes osteosarcoma cell proliferation and metastasis through the BMP-9/PI3K/AKT pathway.
Chen H, Pan R, Li H, Zhang W, Ren C, Lu Q, Chen H, Zhang X, Nie Y
Cell biology international 2021 Mar;45(3):623-632
Cell biology international 2021 Mar;45(3):623-632
Syndecan-3 contributes to the regulation of the microenvironment at the node of Ranvier following end-to‑side neurorrhaphy: sodium image analysis.
Liu CH, Kuo YC, Wang CY, Hsu CC, Ho YJ, Chiang YC, Mai FD, Lin WJ, Liao WC
Histochemistry and cell biology 2021 Mar;155(3):355-367
Histochemistry and cell biology 2021 Mar;155(3):355-367
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Choi MH, Kim J, Ha JH, Park JU
Scientific reports 2021 Mar 9;11(1):5468
Scientific reports 2021 Mar 9;11(1):5468
Jinfukang regulates integrin/Src pathway and anoikis mediating circulating lung cancer cells migration.
Que ZJ, Yang Y, Liu HT, Shang-Guan WJ, Yu P, Zhu LH, Li HG, Liu HM, Tian JH
Journal of ethnopharmacology 2021 Mar 1;267:113473
Journal of ethnopharmacology 2021 Mar 1;267:113473
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Decursin inhibits the growth of HeLa cervical cancer cells through PI3K/Akt signaling.
Zhu ML, Li JC, Wang L, Zhong X, Zhang YW, Tan RZ, Wang HL, Fan JM, Wang L
Journal of Asian natural products research 2021 Jun;23(6):584-595
Journal of Asian natural products research 2021 Jun;23(6):584-595
Quercetin inhibits invasion and angiogenesis of esophageal cancer cells.
Liu Y, Li CL, Xu QQ, Cheng D, Liu KD, Sun ZQ
Pathology, research and practice 2021 Jun;222:153455
Pathology, research and practice 2021 Jun;222:153455
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
Liao R, Feng Z, Li W, Liu R, Xu X, Yao S, Tian J
Experimental and therapeutic medicine 2021 Jun;21(6):640
Experimental and therapeutic medicine 2021 Jun;21(6):640
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Xu J, Wang Y, Wang Z, Wang Y, He X
Steroids 2021 Jun;170:108828
Steroids 2021 Jun;170:108828
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Impairment of corneal epithelial wound healing is association with increased neutrophil infiltration and reactive oxygen species activation in tenascin X-deficient mice.
Sumioka T, Iwanishi H, Okada Y, Miyajima M, Ichikawa K, Reinach PS, Matsumoto KI, Saika S
Laboratory investigation; a journal of technical methods and pathology 2021 Jun;101(6):690-700
Laboratory investigation; a journal of technical methods and pathology 2021 Jun;101(6):690-700
IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.
Chen Y, Qin Y, Dai M, Liu L, Ni Y, Sun Q, Li L, Zhou Y, Qiu C, Jiang Y
Cancer medicine 2021 Jun;10(12):4030-4045
Cancer medicine 2021 Jun;10(12):4030-4045
COL5A1 Variants Cause Aortic Dissection by Activating TGF-β-Signaling Pathway.
Chen P, Yu B, Li Z, Chen Y, Sun Y, Wang DW
Journal of the American Heart Association 2021 Jun;10(11):e019276
Journal of the American Heart Association 2021 Jun;10(11):e019276
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
Li X, Wang C, Wang S, Hu Y, Jin S, Liu O, Gou R, Nie X, Liu J, Lin B
Cancer cell international 2021 Jun 9;21(1):302
Cancer cell international 2021 Jun 9;21(1):302
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y
Cell death & disease 2021 Jun 9;12(6):595
Cell death & disease 2021 Jun 9;12(6):595
Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3β/ZEB1 pathway.
Lv F, Du Q, Li L, Xi X, Liu Q, Li W, Liu S
European journal of pharmacology 2021 Jun 5;900:174069
European journal of pharmacology 2021 Jun 5;900:174069
Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ Prolapse.
Zhao Y, Xia Z, Lin T, Qin M
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 28;27:e930433
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 28;27:e930433
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Duan RN, Yang CL, Du T, Liu A, Wang AR, Sun WJ, Li X, Li JX, Yan CZ, Liu QJ
Journal of neuroinflammation 2021 Jun 28;18(1):145
Journal of neuroinflammation 2021 Jun 28;18(1):145
Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation.
Takashima Y, Hayashi S, Fukuda K, Maeda T, Tsubosaka M, Kamenaga T, Kikuchi K, Fujita M, Kuroda Y, Hashimoto S, Nakano N, Matsumoto T, Kuroda R
Scientific reports 2021 Jun 15;11(1):12516
Scientific reports 2021 Jun 15;11(1):12516
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Liu X, Lv Z, Zhou S, Kan S, Liu X, Jing P, Xu W
International immunopharmacology 2021 Jul;96:107776
International immunopharmacology 2021 Jul;96:107776
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Liu X, Jin J, Liu Y, Shen Z, Zhao R, Ou L, Xing T
International immunopharmacology 2021 Jul;96:107618
International immunopharmacology 2021 Jul;96:107618
High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.
Li C, Shi L, Wang Y, Peng C, Wu L, Zhang Y, Du Z
Environmental toxicology 2021 Jul;36(7):1412-1421
Environmental toxicology 2021 Jul;36(7):1412-1421
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Du T, Wang D, Wan X, Xu J, Xiao Q, Liu B
Oncology letters 2021 Jul;22(1):516
Oncology letters 2021 Jul;22(1):516
Melittin inhibits lung metastasis of human osteosarcoma: Evidence of wnt/β-catenin signaling pathway participation.
Zhu H, Chen D, Xie X, Li Y, Fan T
Toxicon : official journal of the International Society on Toxinology 2021 Jul 30;198:132-142
Toxicon : official journal of the International Society on Toxinology 2021 Jul 30;198:132-142
Upregulation of Rpn10 promotes tumor progression via activation of the NF-κB pathway in clear cell renal cell carcinoma.
Huang T, Tian W, Zhou Q, Li J, Jiang Z, Chen J, Ge C, Tian H
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):988-996
Acta biochimica et biophysica Sinica 2021 Jul 28;53(8):988-996
Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability.
Peng J, Le CY, Xia B, Wang JW, Liu JJ, Li Z, Zhang QJ, Zhang Q, Wang J, Wan CW
BMC cardiovascular disorders 2021 Jul 28;21(1):356
BMC cardiovascular disorders 2021 Jul 28;21(1):356
Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
Sun XL, Zhu ML, Dai YQ, Li HM, Li BH, Ma H, Zhang CH, Wu CZ
Molecules (Basel, Switzerland) 2021 Jul 15;26(14)
Molecules (Basel, Switzerland) 2021 Jul 15;26(14)
Abiotic Mimic of Matrix Metalloproteinase-9 Inhibitor against Advanced Metastatic Cancer.
Zhang T, Dar KK, Li Y, Guo J, Sun W, Shea KJ, Tan T, Lv Y
ACS biomaterials science & engineering 2021 Jul 12;7(7):3190-3200
ACS biomaterials science & engineering 2021 Jul 12;7(7):3190-3200
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition.
Su Y, Zhou L, Yu Q, Lu J, Liu W
Technology in cancer research & treatment 2021 Jan-Dec;20:1533033821997834
Technology in cancer research & treatment 2021 Jan-Dec;20:1533033821997834
C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.
Zhang W, Feng G
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
Sulforaphane Inhibits Osteoclastogenesis via Suppression of the Autophagic Pathway.
Luo T, Fu X, Liu Y, Ji Y, Shang Z
Molecules (Basel, Switzerland) 2021 Jan 12;26(2)
Molecules (Basel, Switzerland) 2021 Jan 12;26(2)
The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer.
He C, Li A, Lai Q, Ding J, Yan Q, Liu S, Li Q
Cell death & disease 2021 Jan 12;12(1):74
Cell death & disease 2021 Jan 12;12(1):74
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Li C, Li Y, Lou L, Han X, Wang H, Huang T, Li C
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
BML-111, the lipoxin A(4) agonist, modulates VEGF or CoCl(2)-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Lin L, Wang Q, Xu F, Luo X, Xu J, Yan L, Li Q, Hao H
Immunology letters 2021 Feb;230:27-35
Immunology letters 2021 Feb;230:27-35
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Guan JH, Cao ZY, Guan B, Wei LH, Peng J, Chen YQ, Sferra TJ, Sankararaman S, Zhan ZX, Lin JM
Translational cancer research 2021 Feb;10(2):953-965
Translational cancer research 2021 Feb;10(2):953-965
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Identification of Key Candidate Genes Involved in the Progression of Idiopathic Pulmonary Fibrosis.
Cui Y, Ji J, Hou J, Tan Y, Han X
Molecules (Basel, Switzerland) 2021 Feb 20;26(4)
Molecules (Basel, Switzerland) 2021 Feb 20;26(4)
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
Ye J, Qi L, Du Z, Yu L, Chen K, Li R, Feng R, Zhai W
Aging 2021 Feb 11;13(4):5607-5620
Aging 2021 Feb 11;13(4):5607-5620
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Wang R, Peng L, Lv D, Shang F, Yan J, Li G, Li D, Ouyang J, Yang J
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Dual-targeting tumor cells and tumor associated macrophages with lipid coated calcium zoledronate for enhanced lung cancer chemoimmunotherapy.
Zang X, Zhou J, Zhang X, Chen D, Han Y, Chen X
International journal of pharmaceutics 2021 Feb 1;594:120174
International journal of pharmaceutics 2021 Feb 1;594:120174
EG-VEGF Induces Invasion of a Human Trophoblast Cell Line via PROKR2.
Tani K, Mitsui T, Mishima S, Ohira A, Maki J, Eto E, Hayata K, Nakamura K, Masuyama H
Acta medica Okayama 2021 Dec;75(6):677-684
Acta medica Okayama 2021 Dec;75(6):677-684
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
Cui L, Zhao X, Jin Z, Wang H, Yang SF, Hu S
Journal of pineal research 2021 Dec;71(4):e12767
Journal of pineal research 2021 Dec;71(4):e12767
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Li M, Ning N, Liu Y, Li X, Mei Q, Zhou J, Huang Q, Xiang W, Zhang L, Xu X
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X, Cui X
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):987-997
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2.
Li B, Liu X, Wu G, Liu J, Cai S, Wang F, Yang C, Liu J
Bioengineered 2021 Dec;12(2):9507-9519
Bioengineered 2021 Dec;12(2):9507-9519
YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.
Sha T, Li J, Sun S, Li J, Zhao X, Li Z, Cui Z
Bioengineered 2021 Dec;12(1):7286-7296
Bioengineered 2021 Dec;12(1):7286-7296
MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway.
Zhou X, Chen Z, Pei L, Sun J
Bioengineered 2021 Dec;12(1):2203-2213
Bioengineered 2021 Dec;12(1):2203-2213
Expression of matrix metalloproteinases during axonal regeneration in the goldfish spinal cord.
Takeda A, Kanemura A, Funakoshi K
Journal of chemical neuroanatomy 2021 Dec;118:102041
Journal of chemical neuroanatomy 2021 Dec;118:102041
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway.
Zhao G, Shi X, Sun Z, Zhao P, Lu Z
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1602-1613
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1602-1613
Uncovering the anti-NSCLC effects and mechanisms of gypenosides by metabolomics and network pharmacology analysis.
Qi YS, Xie JB, Xie P, Duan Y, Ling YQ, Gu YL, Piao XL
Journal of ethnopharmacology 2021 Dec 5;281:114506
Journal of ethnopharmacology 2021 Dec 5;281:114506
Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response.
Li Z, Wang Q, Li L, Chen Y, Cui J, Liu M, Zhang N, Liu Z, Han J, Wang Z
Journal of medicinal chemistry 2021 Dec 23;64(24):17920-17935
Journal of medicinal chemistry 2021 Dec 23;64(24):17920-17935
Arsenic-induced lung inflammation and fibrosis in a rat model: Contribution of the HMGB1/RAGE, PI3K/AKT, and TGF-β1/SMAD pathways.
Wang W, Zheng F, Zhang A
Toxicology and applied pharmacology 2021 Dec 1;432:115757
Toxicology and applied pharmacology 2021 Dec 1;432:115757
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy.
Xue S, Zhou X, Sang W, Wang C, Lu H, Xu Y, Zhong Y, Zhu L, He C, Ma J
Bioactive materials 2021 Aug;6(8):2372-2389
Bioactive materials 2021 Aug;6(8):2372-2389
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway.
Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, Yu H, Chen K, Hu Q, Xia X, Liu S, Guan W
Clinical and translational medicine 2021 Aug;11(8):e522
Clinical and translational medicine 2021 Aug;11(8):e522
Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway.
Wang D, Hu A, Peng H, Li D, Zhang L
3 Biotech 2021 Aug;11(8):380
3 Biotech 2021 Aug;11(8):380
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Chen X, Zhang W, Xu X
World journal of surgical oncology 2021 Aug 6;19(1):232
World journal of surgical oncology 2021 Aug 6;19(1):232
The protective effect of HOXA5 on carotid atherosclerosis occurs by modulating the vascular smooth muscle cell phenotype.
Jing Y, Gao B, Han Z, Xia L, Xin S
Molecular and cellular endocrinology 2021 Aug 20;534:111366
Molecular and cellular endocrinology 2021 Aug 20;534:111366
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Wang X, Zhang X, Qiu T, Yang Y, Li Q, Zhang X
Experimental cell research 2021 Aug 15;405(2):112703
Experimental cell research 2021 Aug 15;405(2):112703
Nitric oxide mediates disruption of human placental trophoblast invasion induced by perfluorobutane sulfonate.
Du Y, Cai Z, Zhang H, Liang W, Wang H, Man Q, Wang W
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117137
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117137
Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model.
Ji W, Zhu P, Liang R, Zhang L, Zhang Y, Wang Y, Zhang W, Tao L, Chen S, Yang H, Jin Y, Duan G
Viruses 2021 Aug 11;13(8)
Viruses 2021 Aug 11;13(8)
Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway.
Luo HL, Luo T, Liu JJ, Wu FX, Bai T, Ou C, Chen J, Li LQ, Zhong JH
Cancer cell international 2021 Aug 10;21(1):422
Cancer cell international 2021 Aug 10;21(1):422
Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway.
Liu J, Zhang Y, Yu C, Zhang P, Gu S, Wang G, Xiao H, Li S
Drug development research 2021 Apr;82(2):278-286
Drug development research 2021 Apr;82(2):278-286
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Ding J, Zhang R, Li H, Ji Q, Cheng X, Thorne RF, Hondermarck H, Liu X, Shen C
Aging 2021 Apr 6;13(7):10703-10723
Aging 2021 Apr 6;13(7):10703-10723
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model.
Chen J, Zhang Y, Wang Y, Jiang P, Zhou G, Li Z, Yang J, Li X
Chinese medicine 2021 Apr 27;16(1):34
Chinese medicine 2021 Apr 27;16(1):34
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Xie Q, Liu Y, Long Y, Wang Z, Jiang S, Ahmed R, Daniyal M, Li B, Liu B, Wang W
Biomaterials science 2021 Apr 21;9(8):2991-3004
Biomaterials science 2021 Apr 21;9(8):2991-3004
Screening and identification of haptoglobin showing its important role in pathophysiological process of gallbladder carcinoma.
Guo L, Liu M, Dou Y, Duan R, Shen L, Jia L, Wang J, Li C, Li X, Liang T
Gene 2021 Apr 15;776:145429
Gene 2021 Apr 15;776:145429
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Guo S, Zhang B, Qi W, Cao X, Xu Y, Zhang X, Li X, Zhou L, Ye L
Toxicology 2021 Apr 15;453:152734
Toxicology 2021 Apr 15;453:152734
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Oncometabolite L-2-hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma.
Wang H, Wang L, Zheng Q, Lu Z, Chen Y, Shen D, Xue D, Jiang M, Ding L, Zhang J, Wu H, Xia L, Qian J, Li G, Lu J
International journal of cancer 2021 Apr 1;148(7):1743-1755
International journal of cancer 2021 Apr 1;148(7):1743-1755
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Matrix Metalloproteinase 9 is Regulated by LOX-1 and erk1/2 Pathway in Dental Peri-Implantitis.
Zhang Q, Xu H, Bai N, Tan F, Xu H, Liu J
Current pharmaceutical biotechnology 2020;21(9):862-871
Current pharmaceutical biotechnology 2020;21(9):862-871
Morusin Inhibits Human Osteosarcoma via the PI3K-AKT Signaling Pathway.
Zhang Y, Weng Q, Chen J, Han J
Current pharmaceutical biotechnology 2020;21(13):1402-1409
Current pharmaceutical biotechnology 2020;21(13):1402-1409
Knockdown of Matrix Metallopeptidase 9 Inhibits Metastasis of Oral Squamous Cell Carcinoma Cells in a Zebrafish Xenograft Model.
Wen J, Yin P, Li L, Kang G, Ning G, Cao Y, Gao F, Su Y, Wu Y, Zhang X
BioMed research international 2020;2020:4350783
BioMed research international 2020;2020:4350783
Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells.
Xi Y, Nie X, Wang J, Gao L, Lin B
BioMed research international 2020;2020:3607436
BioMed research international 2020;2020:3607436
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, Xiong Z, Yang S
BioMed research international 2020;2020:3126182
BioMed research international 2020;2020:3126182
Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells.
Jing X, Du L, Niu A, Wang Y, Wang Y, Wang C
BioMed research international 2020;2020:1276328
BioMed research international 2020;2020:1276328
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
Yuan Q, Yu H, Chen J, Song X, Sun L
Cancer cell international 2020;20:99
Cancer cell international 2020;20:99
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Wang S, Wang C, Li X, Hu Y, Gou R, Guo Q, Nie X, Liu J, Zhu L, Lin B
Cancer cell international 2020;20:418
Cancer cell international 2020;20:418
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Chen SM, Lin CE, Chen HH, Cheng YF, Cheng HW, Imai K
PloS one 2020;15(1):e0227838
PloS one 2020;15(1):e0227838
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
Liu H, Liao W, Fan L, Zheng Z, Liu D, Zhang QW, Yang A, Liu F
Chinese medicine 2020;15:11
Chinese medicine 2020;15:11
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Wang H, Ding Y, Zhang W, Wei K, Pei Y, Zou C, Zhang C, Ding J, Fang H, Tan S
Drug design, development and therapy 2020;14:921-931
Drug design, development and therapy 2020;14:921-931
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y
Frontiers in cellular neuroscience 2020;14:578060
Frontiers in cellular neuroscience 2020;14:578060
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Wang H, Jiang Z, Pang Z, Zhou T, Gu Y
Drug design, development and therapy 2020;14:4801-4813
Drug design, development and therapy 2020;14:4801-4813
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway.
Zheng P, Li L
OncoTargets and therapy 2020;13:451-463
OncoTargets and therapy 2020;13:451-463
5-HT(7) Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells.
Du X, Wang T, Wang Z, Wu X, Gu Y, Huang Q, Wang J, Xie J
OncoTargets and therapy 2020;13:2139-2151
OncoTargets and therapy 2020;13:2139-2151
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z
OncoTargets and therapy 2020;13:1993-2006
OncoTargets and therapy 2020;13:1993-2006
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
Yuan Q, Yu H, Chen J, Song X, Sun L
OncoTargets and therapy 2020;13:1637-1647
OncoTargets and therapy 2020;13:1637-1647
Hydroxysafflor yellow A promotes multiterritory perforating flap survival: an experimental study.
Zhang C, Shao Z, Chen Z, Lin C, Hu S, Lou Z, Li J, Zheng X, Lin N, Gao W
American journal of translational research 2020;12(8):4781-4794
American journal of translational research 2020;12(8):4781-4794
Overexpression of TEM8 promotes ovarian cancer progression via Rac1/Cdc42/JNK and MEK/ERK/STAT3 signaling pathways.
Wang CX, Xiong HF, Wang S, Wang J, Nie X, Guo Q, Li X, Qi Y, Liu JJ, Lin B
American journal of translational research 2020;12(7):3557-3576
American journal of translational research 2020;12(7):3557-3576
S1PR2 Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation.
Pang M, Li C, Zheng D, Wang Y, Wang J, Zhang W, Li F, Jing H
Cancer management and research 2020;12:7857-7865
Cancer management and research 2020;12:7857-7865
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Lv Z, Wu K, Qin X, Yuan J, Yan M, Zhang J, Wang L, Ji T, Cao W, Chen W
Cancer management and research 2020;12:4855-4869
Cancer management and research 2020;12:4855-4869
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
Cui X, Zhang H, Cao A, Cao L, Hu X
Journal of Cancer 2020;11(7):1800-1807
Journal of Cancer 2020;11(7):1800-1807
Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.
Yu J, Wang W, Yao W, Yang Z, Gao P, Liu M, Wang H, Chen S, Wang D, Wang W, Sun G
Journal of Cancer 2020;11(19):5568-5577
Journal of Cancer 2020;11(19):5568-5577
Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression.
Jin Y, Liu J, Liu Y, Liu Y, Guo G, Yu S, An R
Frontiers in pharmacology 2020;11:808
Frontiers in pharmacology 2020;11:808
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Li B, Chen Z, Luo X, Zhang C, Chen H, Wang S, Zhao M, Ma H, Liu J, Cheng M, Yang Y, Yan H
Frontiers in pharmacology 2020;11:612932
Frontiers in pharmacology 2020;11:612932
RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis.
Tatomir A, Beltrand A, Nguyen V, Boodhoo D, Mekala A, Cudrici C, Badea TC, Muresanu DF, Rus V, Rus H
Frontiers in immunology 2020;11:608294
Frontiers in immunology 2020;11:608294
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Yi X, Xu C, Huang P, Zhang L, Qing T, Li J, Wang C, Zeng T, Lu J, Han Z
Frontiers in pharmacology 2020;11:1197
Frontiers in pharmacology 2020;11:1197
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Wang J, Fang Z, Song C, Kang H, Guo Q, Dong Y, Zhang Y, Peng R, Guan H, Li F
Frontiers in pharmacology 2020;11:1175
Frontiers in pharmacology 2020;11:1175
Cyclin G2 Inhibits Oral Squamous Cell Carcinoma Growth and Metastasis by Binding to IGFBP3 and Regulating the FAK-SRC-STAT Signaling Pathway.
Wang D, Gao J, Zhao C, Li S, Zhang D, Hou X, Zhuang X, Liu Q, Luo Y
Frontiers in oncology 2020;10:560572
Frontiers in oncology 2020;10:560572
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Guo W, Zhang Z, Li G, Lai X, Gu R, Xu W, Chen H, Xing Z, Chen L, Qian J, Xu S, Zeng F, Deng F
Frontiers in oncology 2020;10:544288
Frontiers in oncology 2020;10:544288
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer.
Huang T, Fan Q, Wang Y, Cui Y, Wang Z, Yang L, Sun X, Wang Y
Frontiers in oncology 2020;10:19
Frontiers in oncology 2020;10:19
Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer.
Zhu W, Liu C, Lu T, Zhang Y, Zhang S, Chen Q, Deng N
Frontiers in oncology 2020;10:1451
Frontiers in oncology 2020;10:1451
Splenectomy enhances the Ly6C(low) phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis.
Zheng Z, Wang H, Li L, Zhang S, Zhang C, Zhang H, Ji F, Liu X, Zhu K, Kong G, Li Z
International immunopharmacology 2020 Sep;86:106762
International immunopharmacology 2020 Sep;86:106762
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Yu J, Sun G, Chen Y, Li L, Wang H, Tu D, Li L, Meng Z, Wang Y
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Ziyuglycoside II exerts antiproliferative and antimetastasis effects on hepatocellular carcinoma cells.
Liao W, Fan L, Zheng Z, Liu H, Deng H, Li M, Liu F, Yang A
Anti-cancer drugs 2020 Sep;31(8):819-827
Anti-cancer drugs 2020 Sep;31(8):819-827
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Li J, Liu J, Yue W, Xu K, Cai W, Cui F, Li Z, Wang W, He J
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
ERK/AKT Inactivation and Apoptosis Induction Associate With Quetiapine-inhibited Cell Survival and Invasion in Hepatocellular Carcinoma Cells.
Lee YJ, Chung JG, Tan ZL, Hsu FT, Liu YC, Lin SS
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2407-2417
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2407-2417
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, Ma F, Gao Q, Chang R, Lee HH, Zhao S, Su J, Li H, Peng J, Chen H, Yin M, Peng C, Yang N, Wang J, Liu J, Liu H, Han L, Chen X
Genome medicine 2020 Sep 28;12(1):83
Genome medicine 2020 Sep 28;12(1):83
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Zheng D, Wu Z, Han J, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 Sep 25;329:109202
Chemico-biological interactions 2020 Sep 25;329:109202
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Kuo PC, Weng WT, Scofield BA, Furnas D, Paraiso HC, Intriago AJ, Bosi KD, Yu IC, Yen JH
Blood advances 2020 Sep 22;4(18):4366-4381
Blood advances 2020 Sep 22;4(18):4366-4381
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882
Cell proliferation 2020 Oct;53(10):e12882
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
Feng D, Liu M, Liu Y, Zhao X, Sun H, Zheng X, Zhu J, Shang F
Oncology letters 2020 Oct;20(4):67
Oncology letters 2020 Oct;20(4):67
Estrogen-decreased hsa_circ_0001649 promotes stromal cell invasion in endometriosis.
Li Q, Li N, Liu H, Du Y, He H, Zhang L, Liu Y
Reproduction (Cambridge, England) 2020 Oct;160(4):511-519
Reproduction (Cambridge, England) 2020 Oct;160(4):511-519
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Guo J, Ren R, Sun K, Yao X, Lin J, Wang G, Guo Z, Xu T, Guo F
Cell death & disease 2020 Oct 13;11(10):847
Cell death & disease 2020 Oct 13;11(10):847
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p.
Zhang G, Yang W, Li D, Li X, Huang J, Huang R, Luo J
Molecular medicine reports 2020 Nov;22(5):3635-3644
Molecular medicine reports 2020 Nov;22(5):3635-3644
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Wu J, Guo L, Qiu X, Ren Y, Li F, Cui W, Song S
British journal of cancer 2020 Nov;123(11):1673-1685
British journal of cancer 2020 Nov;123(11):1673-1685
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Guo Y, Cao F, Hu S, Liu S, Sun H, Li A, Li F
Discovery medicine 2020 Nov-Dec;30(161):145-153
Discovery medicine 2020 Nov-Dec;30(161):145-153
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Niu X, Lin X, Chen X, Xu S, Huang Z, Tang Q
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity.
Jiang X, Xu Y, Ren H, Jiang J, Wudu M, Wang Q, Guan J, Su H, Zhang Y, Zhang B, Guo Y, Hu Y, Jiang L, Liu Z, Wang H, Cheng Y, Sun L, Qiu X
Cell & bioscience 2020 Nov 27;10(1):139
Cell & bioscience 2020 Nov 27;10(1):139
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Ying X, Xie Q, Li S, Yu X, Zhou K, Yue J, Chen X, Tu W, Yang G, Jiang S
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways.
Chuang HC, Tsai KL, Tsai KJ, Tu TY, Shyong YJ, Jou IM, Hsu CC, Shih SS, Liu YF, Lin CL
Aging 2020 Nov 20;12(23):24168-24183
Aging 2020 Nov 20;12(23):24168-24183
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
Dou Z, Gao L, Ren W, Zhang H, Wang X, Li S, Zheng J, Kong X, Chi P, Zhi K
Experimental cell research 2020 Nov 15;396(2):112290
Experimental cell research 2020 Nov 15;396(2):112290
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956
IUBMB life 2020 May;72(5):942-956
LncRNA ZEB2-AS1 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma cell through miR-574-3p/HMGA2 axis.
Xu JH, Chen RZ, Liu LY, Li XM, Wu CP, Zhou YT, Yan JD, Zhang ZY
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
European review for medical and pharmacological sciences 2020 May;24(10):5391-5403
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
Sun YS, Thakur K, Hu F, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
Li S, Hou X, Wu C, Han L, Li Q, Wang J, Luo S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
Wang N, Lu K, Qu H, Wang H, Chen Y, Shan T, Ge X, Wei Y, Zhou P, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 May 25;323:109074
Chemico-biological interactions 2020 May 25;323:109074
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Yan K, Wu C, Ye Y, Li L, Wang X, He W, Ren S, Xu Y
Cell proliferation 2020 Mar;53(3):e12778
Cell proliferation 2020 Mar;53(3):e12778
Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway.
Chen K, Jiao J, Xue J, Chen T, Hou Y, Jiang Y, Qian L, Wang Y, Ma Z, Liang Z, Sun B, Ren Q
Oncology reports 2020 Mar;43(3):886-896
Oncology reports 2020 Mar;43(3):886-896
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Zhao CC, Yu WW, Qi YJ, Xu LF, Wang ZR, Qiang YW, Ma F, Ma XL
Anti-cancer drugs 2020 Mar;31(3):223-230
Anti-cancer drugs 2020 Mar;31(3):223-230
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Zhu M, Liu H, Sun K, Liu J, Mou Y, Qi D, Zhou C, Abudunaibi M, Tasiken B, Li J, Cheng H, Huang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Comparative peptidome profiling reveals critical roles for peptides in the pathology of pancreatic cancer.
Li X, Li J, Zhang B, Gu Y, Li Q, Gu G, Xiong J, Li Y, Yang X, Qian Z
The international journal of biochemistry & cell biology 2020 Mar;120:105687
The international journal of biochemistry & cell biology 2020 Mar;120:105687
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
Liu S, Dai Y, Zhou C, Zhu T
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
Glycofullerenes Inhibit Particulate Matter Induced Inflammation and Loss of Barrier Proteins in HaCaT Human Keratinocytes.
Lee CW, Su YH, Chiang YC, Lee IT, Li SY, Lee HC, Hsu LF, Yan YL, Li HY, Chen MC, Peng KT, Lai CH
Biomolecules 2020 Mar 28;10(4)
Biomolecules 2020 Mar 28;10(4)
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, Lin Y, Wang Z
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function.
Qu Q, Pang Y, Zhang C, Liu L, Bi Y
Stem cell research & therapy 2020 Mar 23;11(1):133
Stem cell research & therapy 2020 Mar 23;11(1):133
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ouyang L, Mu X, Wang J, Li Q, Gao Y, Liu H, Sun S, Ren Q, Yan R, Wang J, Liu Q, Sun Y, Liu C, He H, Long W, Zhang XD
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, Zhan Z, Sferra TJ, Sankararaman S, Lin J
The Journal of international medical research 2020 Jun;48(6):300060520925598
The Journal of international medical research 2020 Jun;48(6):300060520925598
M2 macrophages promote vasculogenesis during retinal neovascularization by regulating bone marrow-derived cells via SDF-1/VEGF.
Wang Y, Chang T, Wu T, Xu W, Dou G, Wang Y, Guo C
Cell and tissue research 2020 Jun;380(3):469-486
Cell and tissue research 2020 Jun;380(3):469-486
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
Wu H, Wei M, Jiang X, Tan J, Xu W, Fan X, Zhang R, Ding C, Zhao F, Shao X, Zhang Z, Shi R, Zhang W, Wu G
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Zeng Z, Gong X, Hu Z
Aging 2020 Jun 21;12(12):11768-11780
Aging 2020 Jun 21;12(12):11768-11780
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
Wang H, Chen H, Jin J, Liu Q, Zhong D, Li G
Life sciences 2020 Jun 15;251:117638
Life sciences 2020 Jun 15;251:117638
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ
Aging 2020 Jun 11;12(12):11667-11684
Aging 2020 Jun 11;12(12):11667-11684
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity.
Wang H, Cai J, Du S, Wei W, Shen X
Experimental cell research 2020 Jun 1;391(1):111984
Experimental cell research 2020 Jun 1;391(1):111984
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
MicroRNA-382-5p is involved in pulmonary inflammation induced by fine particulate matter exposure.
Zhang X, Zhang Y, Meng Q, Sun H, Wu S, Xu J, Yun J, Yang X, Li B, Zhu H, Xue L, Li X, Chen R
Environmental pollution (Barking, Essex : 1987) 2020 Jul;262:114278
Environmental pollution (Barking, Essex : 1987) 2020 Jul;262:114278
Metastasis-associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c-Jun/MMPs pathway.
Su Z, Yang B, Zeng Z, Zhu S, Wang C, Lei S, Jiang Y, Lin L
Oncology letters 2020 Jul;20(1):99-112
Oncology letters 2020 Jul;20(1):99-112
miR-429-CRKL axis regulates clear cell renal cell carcinoma malignant progression through SOS1/MEK/ERK/MMP2/MMP9 pathway.
Wang J, Wang C, Li Q, Guo C, Sun W, Zhao D, Jiang S, Hao L, Tian Y, Liu S, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110215
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
Qian W, Xiao Q, Wang L, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Duan W, Ma Q, Ma J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation.
Xu S, Pan X, Mao L, Pan H, Xu W, Hu Y, Yu X, Chen Z, Qian S, Ye Y, Huang Y, Pan J
Cell communication and signaling : CCS 2020 Jul 8;18(1):104
Cell communication and signaling : CCS 2020 Jul 8;18(1):104
LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, Yang J, Yao Y, Yan J, Zhao L, Li H, Yang L
Cell death & disease 2020 Jul 24;11(7):576
Cell death & disease 2020 Jul 24;11(7):576
Silencing matrix metalloproteinase 9 exerts a protective effect on astrocytes after oxygen-glucose deprivation and is correlated with suppression of aquaporin-4.
Li S, Li Y, Huang S, Fan B, Wei J, Ouyang L, Chen Z, Jiang B
Neuroscience letters 2020 Jul 13;731:135047
Neuroscience letters 2020 Jul 13;731:135047
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.
Zhang Y, Cong X, Li Z, Xue Y
International immunopharmacology 2020 Jan;78:105937
International immunopharmacology 2020 Jan;78:105937
KCNN4 promotes invasion and metastasis through the MAPK/ERK pathway in hepatocellular carcinoma.
Li QT, Feng YM, Ke ZH, Qiu MJ, He XX, Wang MM, Li YN, Xu J, Shi LL, Xiong ZF
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2020 Jan;68(1):68-74
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2020 Jan;68(1):68-74
MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.
Fan B, Jin Y, Zhang H, Zhao R, Sun M, Sun M, Yuan X, Wang W, Wang X, Chen Z, Liu W, Yu N, Wang Q, Liu T, Li X
International journal of oncology 2020 Jan;56(1):178-192
International journal of oncology 2020 Jan;56(1):178-192
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X
International journal of molecular medicine 2020 Jan;45(1):175-185
International journal of molecular medicine 2020 Jan;45(1):175-185
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356
Redox biology 2020 Jan;28:101356
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
Circular RNA circ_001621 promotes osteosarcoma cells proliferation and migration by sponging miR-578 and regulating VEGF expression.
Ji X, Shan L, Shen P, He M
Cell death & disease 2020 Jan 6;11(1):18
Cell death & disease 2020 Jan 6;11(1):18
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Zhao X, Zhang C, Wei X, Shi L, Dai S, Jia J, Wei S, Wang Y, Wang Y, Cheng J, Zhao L
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
Environmental and molecular mutagenesis 2020 Feb;61(2):256-265
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart.
Govindappa PK, Patil M, Garikipati VNS, Verma SK, Saheera S, Narasimhan G, Zhu W, Kishore R, Zhang J, Krishnamurthy P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2238-2251
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2238-2251
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Wang J, Guan H, Liu H, Lei Z, Kang H, Guo Q, Dong Y, Liu H, Sun Y, Fang Z, Li F
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p.
Jiang G, Dong H, Dong Y, Yang X
Molecular medicine reports 2020 Feb;21(2):768-776
Molecular medicine reports 2020 Feb;21(2):768-776
Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway.
Zhang Y, Weng Q, Han J, Chen J
Molecular medicine reports 2020 Feb;21(2):675-684
Molecular medicine reports 2020 Feb;21(2):675-684
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
Xue J, Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Li H, Jiang W, Li G, Zhao W, Zhang X
Cancer letters 2020 Feb 28;471:12-26
Cancer letters 2020 Feb 28;471:12-26
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
Gao L, Nie X, Zheng M, Li X, Guo Q, Liu J, Liu Q, Hao Y, Lin B
Life sciences 2020 Feb 15;243:116910
Life sciences 2020 Feb 15;243:116910
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Wang Y, Su NX, Pan SG, Ge XP, Dai XP
Pharmaceutical biology 2020 Dec;58(1):878-885
Pharmaceutical biology 2020 Dec;58(1):878-885
Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.
Lu J, Li Y
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
Molecular and cellular biochemistry 2020 Dec;475(1-2):227-237
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma.
Zhang W, Han L, Xing P, Liu B, Sun Z, Zhou W, Dong J
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
Naunyn-Schmiedeberg's archives of pharmacology 2020 Dec;393(12):2543-2551
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Guan J, Jiang X, Gai J, Sun X, Zhao J, Li J, Li Y, Cheng M, Du T, Fu L, Li Q
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
Qiu Y, Maione F, Capano S, Meda C, Picconi O, Brundu S, Pisacane A, Sapino A, Palladino C, Barillari G, Monini P, Bussolino F, Ensoli B, Sgadari C, Giraudo E
Molecular cancer therapeutics 2020 Dec;19(12):2476-2489
Molecular cancer therapeutics 2020 Dec;19(12):2476-2489
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway.
Hua R, Zhang X, Li W, Lian W, Liu Q, Gao D, Wang Y, Lei M
Journal of cell science 2020 Dec 9;133(23)
Journal of cell science 2020 Dec 9;133(23)
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.
Li W, Wang D, Ge Y, Zhang L, Wu J, Liu D
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
Molecules (Basel, Switzerland) 2020 Dec 23;26(1)
PRCC-TFE3 regulates migration and invasion of translocation renal cell carcinomas via activation of Drp1-dependent mitochondrial fission.
Wang B, Gan W, Han X, Li D
Cell biology international 2020 Aug;44(8):1727-1733
Cell biology international 2020 Aug;44(8):1727-1733
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
MicroRNA-505-3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression.
Cheng Z, Wang B, Zhang C
Oncology letters 2020 Aug;20(2):1663-1670
Oncology letters 2020 Aug;20(2):1663-1670
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Wu M, Tan X, Liu P, Yang Y, Huang Y, Liu X, Meng X, Yu B, Wu Y, Jin H
Life sciences 2020 Aug 15;255:117857
Life sciences 2020 Aug 15;255:117857
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Liu W, Li Y, Feng S, Guan Y, Cao Y
Journal of biochemistry 2020 Aug 1;168(2):159-170
Journal of biochemistry 2020 Aug 1;168(2):159-170
MicroRNA-1298-5p inhibits cell proliferation and the invasiveness of bladder cancer cells via down-regulation of connexin 43.
Li G, Sun L, Mu Z, Liu S, Qu H, Xie Q, Hu B
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):227-237
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):227-237
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Andrographolide attenuates oxidative stress injury in cigarette smoke extract exposed macrophages through inhibiting SIRT1/ERK signaling.
Zhang XF, Ding MJ, Cheng C, Zhang Y, Xiang SY, Lu J, Liu ZB
International immunopharmacology 2020 Apr;81:106230
International immunopharmacology 2020 Apr;81:106230
Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy.
Zhang M, Wang X, Liu M, Liu D, Pan J, Tian J, Jin T, Xu Y, An F
Journal of cellular and molecular medicine 2020 Apr;24(8):4612-4623
Journal of cellular and molecular medicine 2020 Apr;24(8):4612-4623
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes.
Liu X, Wang X, Liu N, Zhu K, Zhang S, Duan X, Huang Y, Jin Z, Jaypaul H, Wu Y, Chen H
Molecular medicine reports 2020 Apr;21(4):1941-1949
Molecular medicine reports 2020 Apr;21(4):1941-1949
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
Gong F, Chai W, Wang J, Cheng H, Shi Y, Cui L, Jia G
Acta histochemica 2020 Apr;122(3):151527
Acta histochemica 2020 Apr;122(3):151527
A systems biology approach for defining the potential molecular framework of idiopathic hypereosinophilic syndrome with cutaneous involvement.
Wang W, Ma J, Sun X, Ba W, Meng X, Zhu Y, Leng L, Li C
Biochemical and biophysical research communications 2020 Apr 9;524(3):567-574
Biochemical and biophysical research communications 2020 Apr 9;524(3):567-574
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Zhao H, Lewellen BM, Wilson RJ, Cui D, Drake JC, Zhang M, Yan Z
Scientific reports 2020 Apr 8;10(1):6095
Scientific reports 2020 Apr 8;10(1):6095
Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation.
Xu J, Zhang Z, Qian M, Wang S, Qiu W, Chen Z, Sun Z, Xiong Y, Wang C, Sun X, Zhao R, Xue H, Li G
Journal of experimental & clinical cancer research : CR 2020 Apr 6;39(1):59
Journal of experimental & clinical cancer research : CR 2020 Apr 6;39(1):59
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Tang H, Chu Y, Huang Z, Cai J, Wang Z
Carcinogenesis 2020 Apr 22;41(2):182-193
Carcinogenesis 2020 Apr 22;41(2):182-193
miR-524-5p inhibits angiogenesis through targeting WNK1 in colon cancer cells.
Li X, Li Z, Zhu Y, Li Z, Yao L, Zhang L, Yuan L, Shang Y, Liu J, Li C
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
American journal of physiology. Gastrointestinal and liver physiology 2020 Apr 1;318(4):G827-G839
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Wang S, Yao Y, Li H, Zheng G, Lu S, Chen W
American journal of cancer research 2019;9(9):1957-1969
American journal of cancer research 2019;9(9):1957-1969
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
Guo Q, Zhu L, Wang C, Wang S, Nie X, Liu J, Liu Q, Hao Y, Li X, Lin B
Frontiers in oncology 2019;9:954
Frontiers in oncology 2019;9:954
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, Xiao G, Li Z
Frontiers in oncology 2019;9:461
Frontiers in oncology 2019;9:461
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Enhancement of Histone Deacetylase Inhibitor Sensitivity in Combination with Cyclin-Dependent Kinase Inhibition for the Treatment of Oral Squamous Cell Carcinoma.
Zhao B, Huang Z, Qin Z, Li Y, Wang T, Wang L, Zhou W, Yu C, Wang X, Yang S, Fan Y, Xiang R
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):141-156
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):141-156
miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways.
Feng X, Yan N, Sun W, Zheng S, Jiang S, Wang J, Guo C, Hao L, Tian Y, Liu S, Sun MZ
Cell death discovery 2019;5:89
Cell death discovery 2019;5:89
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
Zhou X, Xiong J, Lu S, Luo L, Chen ZL, Yang F, Jin F, Wang Y, Ma Q, Luo YY, Wang YJ, Zhou JB, Liu P, Zhao L
The American journal of Chinese medicine 2019;47(7):1541-1569
The American journal of Chinese medicine 2019;47(7):1541-1569
miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway.
Wu T, Hu H, Zhang T, Jiang L, Li X, Liu S, Zheng C, Yan G, Chen W, Ning Y, Li Y, Lu Z
Oxidative medicine and cellular longevity 2019;2019:9719723
Oxidative medicine and cellular longevity 2019;2019:9719723
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Gao X, Jiang S, Du Z, Ke A, Liang Q, Li X
Oxidative medicine and cellular longevity 2019;2019:8564681
Oxidative medicine and cellular longevity 2019;2019:8564681
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Yao H, Wei S, Xiang Y, Wu Z, Liu W, Wang B, Li X, Xu H, Zhao J, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, Zuo D, Zhang W, Wu Y
Cancer biology & therapy 2019;20(4):513-523
Cancer biology & therapy 2019;20(4):513-523
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
Wang J, Zheng M, Zhu L, Deng L, Li X, Gao L, Wang C, Wang H, Liu J, Lin B
Cancer cell international 2019;19:330
Cancer cell international 2019;19:330
SKA1 promotes malignant phenotype and progression of glioma via multiple signaling pathways.
Wang X, Zeng Y, Zhou M, Zhang X, Xu A, Lin J, Wu Z, Xie C, Luo J, Ding S, Zhan Z, Long H, Song Y
Cancer cell international 2019;19:324
Cancer cell international 2019;19:324
Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA.
Wang L, Zhao F, Xiao Z, Yao L
Cancer cell international 2019;19:281
Cancer cell international 2019;19:281
Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner.
Yu S, Zhou R, Yang T, Liu S, Cui Z, Qiao Q, Zhang J
Cancer cell international 2019;19:116
Cancer cell international 2019;19:116
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis.
Feng H, Zhao X, Guo Q, Feng Y, Ma M, Guo W, Dong X, Deng C, Li C, Song X, Han S, Cao L
International journal of biological sciences 2019;15(3):507-521
International journal of biological sciences 2019;15(3):507-521
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway.
Wu H, Ding J, Li S, Lin J, Jiang R, Lin C, Dai L, Xie C, Lin D, Xu H, Gao W, Zhou K
International journal of biological sciences 2019;15(2):325-340
International journal of biological sciences 2019;15(2):325-340
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Xia B, Wang J
Drug design, development and therapy 2019;13:3837-3844
Drug design, development and therapy 2019;13:3837-3844
Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress.
Lin J, Jia C, Wang Y, Jiang S, Jia Z, Chen N, Sheng S, Li S, Jiang L, Xu H, Zhou K, Chen Y
Drug design, development and therapy 2019;13:1461-1472
Drug design, development and therapy 2019;13:1461-1472
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and therapy 2019;12:2397-2408
OncoTargets and therapy 2019;12:2397-2408
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Gu Y, Li C, Xiao L, Li J, Pei H, Xu D, Jiang Y, Zhang X, Zhang L, Li K, Zhu Z, Chen X
American journal of translational research 2019;11(9):5438-5456
American journal of translational research 2019;11(9):5438-5456
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
American journal of translational research 2019;11(1):379-392
American journal of translational research 2019;11(1):379-392
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Nie X, Liu C, Guo Q, Zheng MJ, Gao LL, Li X, Liu DW, Zhu LC, Liu JJ, Lin B
Cancer management and research 2019;11:839-855
Cancer management and research 2019;11:839-855
Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis.
Wang Z, Yang MQ, Lei L, Fei LR, Zheng YW, Huang WJ, Li ZH, Liu CC, Xu HT
Cancer management and research 2019;11:7485-7497
Cancer management and research 2019;11:7485-7497
Downregulation of RAI14 inhibits the proliferation and invasion of breast cancer cells.
Gu M, Zheng W, Zhang M, Dong X, Zhao Y, Wang S, Jiang H, Liu L, Zheng X
Journal of Cancer 2019;10(25):6341-6348
Journal of Cancer 2019;10(25):6341-6348
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Suo L, Chang X, Xu N, Ji H
Frontiers in endocrinology 2019;10:370
Frontiers in endocrinology 2019;10:370
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Chen Y, Liu H, Huang H, Ma Y, Wang R, Hu Y, Zheng X, Chen C, Tang H
Frontiers in pharmacology 2019;10:1574
Frontiers in pharmacology 2019;10:1574
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
Li J, Bao G, ALyafeai E, Ding J, Li S, Sheng S, Shen Z, Jia Z, Lin C, Zhang C, Lou Z, Xu H, Gao W, Zhou K
Frontiers in pharmacology 2019;10:1017
Frontiers in pharmacology 2019;10:1017
SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.
Gu X, Jiang Y, Xue W, Song C, Wang Y, Liu Y, Cui B
Clinical and experimental pharmacology & physiology 2019 Sep;46(9):861-871
Clinical and experimental pharmacology & physiology 2019 Sep;46(9):861-871
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Lou Z, Peng Z, Wang B, Li X, Li X, Zhang X
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
Wang P, Liu X, Han G, Dai S, Ni Q, Xiao S, Huang J
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
Experimental & molecular medicine 2019 Sep 25;51(9):1-16
HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.
Zhu H, Dai W, Li J, Xiang L, Wu X, Tang W, Chen Y, Yang Q, Liu M, Xiao Y, Zhang W, Lin J, Wang J, Liu G, Sun Y, Jiang P, Li G, Li A, Liu S, Chen Y, Wang J
Journal of experimental & clinical cancer research : CR 2019 Sep 23;38(1):412
Journal of experimental & clinical cancer research : CR 2019 Sep 23;38(1):412
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma.
Zhong B, Shi D, Wu F, Wang S, Hu H, Cheng C, Qing X, Huang X, Luo X, Zhang Z, Shao Z
Cell death & disease 2019 Sep 18;10(10):687
Cell death & disease 2019 Sep 18;10(10):687
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Sijunzi decoction may decrease apoptosis via stabilization of the extracellular matrix following cerebral ischaemia-reperfusion in rats.
Yang P, Tian YM, Deng WX, Cai X, Liu WH, Li L, Huang HY
Experimental and therapeutic medicine 2019 Oct;18(4):2805-2812
Experimental and therapeutic medicine 2019 Oct;18(4):2805-2812
Hyperoside protects against heart failure-induced liver fibrosis in rats.
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W
Acta histochemica 2019 Oct;121(7):804-811
Acta histochemica 2019 Oct;121(7):804-811
Ricolinostat (ACY-1215) inhibits VEGF expression via PI3K/AKT pathway and promotes apoptosis in osteoarthritic osteoblasts.
Li L, Liu F, Huang W, Wang J, Wan Y, Li M, Pang Y, Yin Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109357
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109357
CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.
Simbulan-Rosenthal CM, Dougherty R, Vakili S, Ferraro AM, Kuo LW, Alobaidi R, Aljehane L, Gaur A, Sykora P, Glasgow E, Agarwal S, Rosenthal DS
Cancers 2019 Oct 3;11(10)
Cancers 2019 Oct 3;11(10)
Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway.
Chen M, Gilbert N, Liu H
Reproductive biology and endocrinology : RB&E 2019 Oct 27;17(1):86
Reproductive biology and endocrinology : RB&E 2019 Oct 27;17(1):86
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Liu M, Liang Y, Zhu Z, Wang J, Cheng X, Cheng J, Xu B, Li R, Liu X, Wang Y
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
Yan R, Sun S, Yang J, Long W, Wang J, Mu X, Li Q, Hao W, Zhang S, Liu H, Gao Y, Ouyang L, Chen J, Liu S, Zhang XD, Ming D
ACS nano 2019 Oct 22;13(10):11552-11560
ACS nano 2019 Oct 22;13(10):11552-11560
20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice.
Liu C, Feng R, Zou J, Xia F, Wan JB
Molecules (Basel, Switzerland) 2019 Oct 16;24(20)
Molecules (Basel, Switzerland) 2019 Oct 16;24(20)
Topically Applied Cross-Linked Hyaluronan Attenuates the Formation of Spinal Epidural Fibrosis in a Swine Model of Laminectomy.
Lin CL, Jou IM, Wu CY, Kuo YR, Yang SC, Lee JS, Tu YK, Chen SC, Huang YH
Scientific reports 2019 Oct 10;9(1):14613
Scientific reports 2019 Oct 10;9(1):14613
Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.
Li Q, Xu A, Chu Y, Chen T, Li H, Yao L, Zhou P, Xu M
Oncology reports 2019 Nov;42(5):1815-1824
Oncology reports 2019 Nov;42(5):1815-1824
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.
Wang Y, Zhou N, Li P, Wu H, Wang Q, Gao X, Wang X, Huang J
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Journal of cellular physiology 2019 Nov;234(11):20408-20419
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Gao L, Zheng M, Guo Q, Nie X, Li X, Hao Y, Liu J, Zhu L, Lin B
The international journal of biochemistry & cell biology 2019 Nov;116:105617
The international journal of biochemistry & cell biology 2019 Nov;116:105617
Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model.
Song X, Lin NH, Wang YL, Chen B, Wang HX, Hu K
Asian journal of andrology 2019 Nov-Dec;21(6):605-611
Asian journal of andrology 2019 Nov-Dec;21(6):605-611
Inhibition of perivascular mast cell activation is involved in the atheroprotective effect of rosiglitazone in apolipoprotein E-deficient mice.
Li Q, Xiao Y, Lu G, Xie D, Zhai Y, Zhang J, Li J, Gao X
Biochemical and biophysical research communications 2019 Nov 5;519(2):261-266
Biochemical and biophysical research communications 2019 Nov 5;519(2):261-266
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation.
Huang A, Honda Y, Li P, Tanaka T, Baba S
International journal of molecular sciences 2019 Nov 30;20(23)
International journal of molecular sciences 2019 Nov 30;20(23)
Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam.
Emmert AS, Iwasawa E, Shula C, Schultz P, Lindquist D, Dunn RS, Fugate EM, Hu YC, Mangano FT, Goto J
Disease models & mechanisms 2019 Nov 21;12(11)
Disease models & mechanisms 2019 Nov 21;12(11)
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, Li J, Deng X, Shui X, Gao W, Ding J, Xiao J, Xu H
Cell death & disease 2019 Nov 18;10(12):872
Cell death & disease 2019 Nov 18;10(12):872
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Lee KF, Tsai MM, Tsai CY, Huang CG, Ou YH, Hsieh CC, Hsieh HL, Wang CS, Lin KH
International journal of molecular sciences 2019 Nov 13;20(22)
International journal of molecular sciences 2019 Nov 13;20(22)
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals.
Xue D, Wang H, Chen Y, Shen D, Lu J, Wang M, Zebibula A, Xu L, Wu H, Li G, Xia L
Molecular cancer 2019 Nov 1;18(1):151
Molecular cancer 2019 Nov 1;18(1):151
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Khan A, Fan K, Sun N, Yin W, Sun Y, Sun P, Jahejo AR, Li H
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury.
Chen L, Kong L, Wei X, Wang Y, Wang B, Zhang X, Sun J, Liu H
Journal of cellular and molecular medicine 2019 May;23(5):3325-3335
Journal of cellular and molecular medicine 2019 May;23(5):3325-3335
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway.
Liu M, Li L, Zhu J, He C, Xu Q, Sun A, Kong W, Li W, Zhang X
Biochemical and biophysical research communications 2019 May 7;512(3):498-504
Biochemical and biophysical research communications 2019 May 7;512(3):498-504
Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, Song F, Li H, Ge H, Qian H, Li X, Tang X, Liu P
Aging 2019 May 10;11(9):2699-2723
Aging 2019 May 10;11(9):2699-2723
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Yin J, Xia W, Wu M, Zhang Y, Huang S, Zhang A, Jia Z
Chemico-biological interactions 2019 May 1;304:73-82
Chemico-biological interactions 2019 May 1;304:73-82
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Zhou F, Jiang Z, Yang B, Hu Z
Brain, behavior, and immunity 2019 Mar;77:161-167
Brain, behavior, and immunity 2019 Mar;77:161-167
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Zhou B, Li W, Zhao G, Yu B, Ma B, Liu Z, Xie N, Fu Y, Gong Z, Dai R, Zhang X, Kong W
Journal of vascular surgery 2019 Mar;69(3):921-932.e3
Journal of vascular surgery 2019 Mar;69(3):921-932.e3
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
Wang S, Yao Y, Rao C, Zheng G, Chen W
International journal of oncology 2019 Mar;54(3):966-980
International journal of oncology 2019 Mar;54(3):966-980
miR‑16‑2‑3p inhibits cell proliferation and migration and induces apoptosis by targeting PDPK1 in maxillary primordium mesenchymal cells.
Han T, Wu N, Wang Y, Shen W, Zou J
International journal of molecular medicine 2019 Mar;43(3):1441-1451
International journal of molecular medicine 2019 Mar;43(3):1441-1451
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Zhang X, Yang X, Zhu S, Li Q, Zou N
Oncology reports 2019 Mar;41(3):1960-1970
Oncology reports 2019 Mar;41(3):1960-1970
Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia.
Zhang X, Zhao HH, Li D, Li HP
Brain research bulletin 2019 Mar;146:136-142
Brain research bulletin 2019 Mar;146:136-142
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer.
Chen J, Yu Y, Li H, Hu Q, Chen X, He Y, Xue C, Ren F, Ren Z, Li J, Liu L, Duan Z, Cui G, Sun R
Molecular cancer 2019 Mar 2;18(1):33
Molecular cancer 2019 Mar 2;18(1):33
AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model.
Wang X, Pan J, Liu H, Zhang M, Liu D, Lu L, Tian J, Liu M, Jin T, An F
Life sciences 2019 Mar 15;221:249-258
Life sciences 2019 Mar 15;221:249-258
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis.
Dai L, Hu W, Yang Z, Chen D, He B, Chen Y, Zhou L, Xie H, Wu J, Zheng S
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):736-748
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):736-748
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Wang L, Li S, Yu X, Han Y, Wu Y, Wang S, Chen X, Zhang J, Wang S
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Journal of physiology and biochemistry 2019 Jun;75(2):199-207
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib.
Yang Z, Zhang J, Lin X, Wu D, Li G, Zhong C, Fang L, Jiang P, Yin L, Zhang L, Bie P, Xie CM
Oncology reports 2019 Jun;41(6):3257-3269
Oncology reports 2019 Jun;41(6):3257-3269
TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease.
Ren J, Gu C, Yang Y, Xue J, Sun Y, Jian F, Chen D, Bian L, Sun Q
Journal of cellular and molecular medicine 2019 Jun;23(6):4097-4110
Journal of cellular and molecular medicine 2019 Jun;23(6):4097-4110
lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis.
Cui C, Wang X, Shang XM, Li L, Ma Y, Zhao GY, Song YX, Geng XB, Zhao BQ, Tian MR, Wang HL
Molecular medicine reports 2019 Jun;19(6):4663-4672
Molecular medicine reports 2019 Jun;19(6):4663-4672
Ectopic expression of CC chemokine receptor 7 promotes prostate cancer cells metastasis via Notch1 signaling.
Du R, Tang G, Tang Z, Kuang Y
Journal of cellular biochemistry 2019 Jun;120(6):9639-9647
Journal of cellular biochemistry 2019 Jun;120(6):9639-9647
Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN.
Lu Q, Liu T, Feng H, Yang R, Zhao X, Chen W, Jiang B, Qin H, Guo X, Liu M, Li L, Guo H
Molecular cancer 2019 Jun 22;18(1):111
Molecular cancer 2019 Jun 22;18(1):111
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway.
Xie Q, Yang Z, Huang X, Zhang Z, Li J, Ju J, Zhang H, Ma J
Journal of hematology & oncology 2019 Jun 11;12(1):60
Journal of hematology & oncology 2019 Jun 11;12(1):60
Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis.
Yao Y, Rao C, Zheng G, Wang S
Oncology reports 2019 Jul;42(1):131-141
Oncology reports 2019 Jul;42(1):131-141
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Liu H, Dong Y, Gao Y, Zhao L, Cai C, Qi D, Zhu M, Zhao L, Liu C, Guo F, Xiao J, Huang H
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3.
Ahmmed B, Kampo S, Khan M, Faqeer A, Kumar SP, Yulin L, Liu JW, Yan Q
Journal of cellular physiology 2019 Jul;234(7):10680-10697
Journal of cellular physiology 2019 Jul;234(7):10680-10697
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-κB pathway activation.
Gao Y, Nan X, Shi X, Mu X, Liu B, Zhu H, Yao B, Liu X, Yang T, Hu Y, Liu S
BMC cancer 2019 Jul 12;19(1):685
BMC cancer 2019 Jul 12;19(1):685
Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-β1/Smad2 signaling pathway.
Chen P, Tian K, Tu W, Zhang Q, Han L, Zhou X
Toxicology and applied pharmacology 2019 Jul 1;374:1-10
Toxicology and applied pharmacology 2019 Jul 1;374:1-10
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Liu SQ, Xu CY, Wu WH, Fu ZH, He SW, Qin MB, Huang JA
International journal of oncology 2019 Jan;54(1):41-52
International journal of oncology 2019 Jan;54(1):41-52
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Yu H, Fu QR, Huang ZJ, Lin JY, Chen QX, Wang Q, Shen DY
Oncology reports 2019 Jan;41(1):213-223
Oncology reports 2019 Jan;41(1):213-223
Matrix stiffness regulates epithelial-mesenchymal transition via cytoskeletal remodeling and MRTF-A translocation in osteosarcoma cells.
Dai J, Qin L, Chen Y, Wang H, Lin G, Li X, Liao H, Fang H
Journal of the mechanical behavior of biomedical materials 2019 Feb;90:226-238
Journal of the mechanical behavior of biomedical materials 2019 Feb;90:226-238
Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.
Fan H, Huang L, Zhuang X, Ai F, Sun W
Cytotechnology 2019 Feb;71(1):35-44
Cytotechnology 2019 Feb;71(1):35-44
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway.
Ahmmed B, Khan MN, Nisar MA, Kampo S, Zheng Q, Li Y, Yan Q
International journal of oncology 2019 Feb;54(2):431-442
International journal of oncology 2019 Feb;54(2):431-442
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Li Y, Chen Y, Qiu C, Ma X, Lei K, Cai G, Liang X, Liu J
Journal of cellular biochemistry 2019 Feb;120(2):1560-1576
Journal of cellular biochemistry 2019 Feb;120(2):1560-1576
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Wei C, Dong X, Lu H, Tong F, Chen L, Zhang R, Dong J, Hu Y, Wu G, Dong X
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Wang WS, Li WJ, Wang YW, Wang LY, Mi YB, Lu JW, Lu Y, Zhang CY, Sun K
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Li X, Xue Y, Liu X, Zheng J, Shen S, Yang C, Chen J, Li Z, Liu L, Ma J, Ma T, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
The antimetastatic effect and underlying mechanisms of thioredoxin reductase inhibitor ethaselen.
Zheng X, Chen Y, Bai M, Liu Y, Xu B, Sun R, Zeng H
Free radical biology & medicine 2019 Feb 1;131:7-17
Free radical biology & medicine 2019 Feb 1;131:7-17
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Zhang P, Chen FZ, Jia QB, Hu DF
IUBMB life 2019 Dec;71(12):1857-1875
IUBMB life 2019 Dec;71(12):1857-1875
Bradykinin promotes proliferation, migration, and invasion of cervical cancer cells through STAT3 signaling pathways.
Wang W, Zhou Y, Wei R, Jiang G, Li F, Chen X, Wang X, Ma D, Xi L
Oncology reports 2019 Dec;42(6):2521-2527
Oncology reports 2019 Dec;42(6):2521-2527
Inhibition of Fibroblast Growth Factor Receptor by AZD4547 Protects Against Inflammation in Septic Mice.
Huang Y, Wang F, Li H, Xu S, Xu W, Pan X, Hu Y, Mao L, Qian S, Pan J
Inflammation 2019 Dec;42(6):1957-1967
Inflammation 2019 Dec;42(6):1957-1967
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy.
Zhang J, Zuo T, Liang X, Xu Y, Yang Y, Fang T, Li J, Chen D, Shen Q
Journal of materials chemistry. B 2019 Dec 7;7(45):7141-7151
Journal of materials chemistry. B 2019 Dec 7;7(45):7141-7151
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Jia Z, Huang Y, Ji X, Sun J, Fu G
BMC cardiovascular disorders 2019 Dec 30;19(1):318
BMC cardiovascular disorders 2019 Dec 30;19(1):318
Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone.
Li L, Li M, Pang Y, Wang J, Wan Y, Zhu C, Yin Z
Life sciences 2019 Dec 15;239:116975
Life sciences 2019 Dec 15;239:116975
Upregulation of fascin-1 is involved in HIF-1α-dependent invasion and migration of hypopharyngeal squamous cell carcinoma.
Bu M, Liu X, Liu X, Xu W
International journal of oncology 2019 Aug;55(2):488-498
International journal of oncology 2019 Aug;55(2):488-498
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway.
Wang X, Pan J, Liu D, Zhang M, Li X, Tian J, Liu M, Jin T, An F
Journal of cellular and molecular medicine 2019 Aug;23(8):5349-5359
Journal of cellular and molecular medicine 2019 Aug;23(8):5349-5359
Water-Soluble Fullerenol C(60)(OH)(36) toward Effective Anti-Air Pollution Induced by Urban Particulate Matter in HaCaT Cell.
Lee CW, Chi MC, Peng KT, Chiang YC, Hsu LF, Yan YL, Li HY, Chen MC, Lee IT, Lai CH
International journal of molecular sciences 2019 Aug 30;20(17)
International journal of molecular sciences 2019 Aug 30;20(17)
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice.
Dimitriadis GK, Nasiri-Ansari N, Agrogiannis G, Kostakis ID, Randeva MS, Nikiteas N, Patel VH, Kaltsas G, Papavassiliou AG, Randeva HS, Kassi E
Molecular and cellular endocrinology 2019 Aug 20;494:110487
Molecular and cellular endocrinology 2019 Aug 20;494:110487
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma.
Wu JS, Li ZF, Wang HF, Yu XH, Pang X, Wu JB, Wang SS, Zhang M, Yang X, Cao MX, Tang YJ, Liang XH, Zheng M, Tang YL
International journal of oncology 2019 Apr;54(4):1233-1244
International journal of oncology 2019 Apr;54(4):1233-1244
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Li Y, Chen X, Cui Y, Wei Q, Chen S, Wang X
Oncology letters 2019 Apr;17(4):3701-3708
Oncology letters 2019 Apr;17(4):3701-3708
Dependence of artesunate on long noncoding RNA-RP11 to inhibit epithelial-mesenchymal transition of hepatocellular carcinoma.
Jing W, Dong H, Min M, Runpeng Z, Xuewei X, Ru C, Yingru X, Shengfa N, Baoxian T, Jinbo Y, Weidong H, Rongbo Z
Journal of cellular biochemistry 2019 Apr;120(4):6026-6034
Journal of cellular biochemistry 2019 Apr;120(4):6026-6034
Cordycepin suppresses cell proliferation and migration by targeting CLEC2 in human gastric cancer cells via Akt signaling pathway.
Wang Y, Lv Y, Liu TS, Yan WD, Chen LY, Li ZH, Piao YS, An RB, Lin ZH, Ren XS
Life sciences 2019 Apr 15;223:110-119
Life sciences 2019 Apr 15;223:110-119
Knockdown of long noncoding RNA CCDC144NL-AS1 attenuates migration and invasion phenotypes in endometrial stromal cells from endometriosis†.
Zhang C, Wu W, Zhu H, Yu X, Zhang Y, Ye X, Cheng H, Ma R, Cui H, Luo J, Guan J, Chang X
Biology of reproduction 2019 Apr 1;100(4):939-949
Biology of reproduction 2019 Apr 1;100(4):939-949
Sodium Tanshinone IIA Sulfonate Decreases Cigarette Smoke-Induced Inflammation and Oxidative Stress via Blocking the Activation of MAPK/HIF-1α Signaling Pathway.
Guan R, Wang J, Li Z, Ding M, Li D, Xu G, Wang T, Chen Y, Yang Q, Long Z, Cai Z, Zhang C, Liang X, Dong L, Zhao L, Zhang H, Sun D, Lu W
Frontiers in pharmacology 2018;9:263
Frontiers in pharmacology 2018;9:263
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
Cai C, Liu C, Zhao L, Liu H, Li W, Guan H, Zhao L, Xiao J
Frontiers in pharmacology 2018;9:1286
Frontiers in pharmacology 2018;9:1286
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
Frontiers in pharmacology 2018;9:1178
Frontiers in pharmacology 2018;9:1178
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
Zhang F, Lu S, He J, Jin H, Wang F, Wu L, Shao J, Chen A, Zheng S
Theranostics 2018;8(3):610-626
Theranostics 2018;8(3):610-626
Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis.
Gao Y, Yu H, Liu Y, Liu X, Zheng J, Ma J, Gong W, Chen J, Zhao L, Tian Y, Xue Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):131-147
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):131-147
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Zhu JF, Liu Y, Huang H, Shan L, Han ZG, Liu JY, Li YL, Dong X, Zeng W
Cancer cell international 2018;18:193
Cancer cell international 2018;18:193
MIR-300 in the imprinted DLK1-DIO3 domain suppresses the migration of bladder cancer by regulating the SP1/MMP9 pathway.
Yan H, Li J, Ying Y, Xie H, Chen H, Xu X, Zheng X
Cell cycle (Georgetown, Tex.) 2018;17(24):2790-2801
Cell cycle (Georgetown, Tex.) 2018;17(24):2790-2801
Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration.
Zhang Y, Yi F, Wang L, Wang Z, Zhang N, Wang Z, Li Z, Song X, Wei S, Cao L
International journal of biological sciences 2018;14(9):1081-1089
International journal of biological sciences 2018;14(9):1081-1089
Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart.
Liu F, Wen Y, Kang J, Wei C, Wang M, Zheng Z, Peng J
International journal of molecular medicine 2018 Sep;42(3):1436-1444
International journal of molecular medicine 2018 Sep;42(3):1436-1444
Upregulated miR-29c suppresses silica-induced lung fibrosis through the Wnt/β-catenin pathway in mice.
Wang X, Xu K, Yang XY, Liu J, Zeng Q, Wang FS
Human & experimental toxicology 2018 Sep;37(9):944-952
Human & experimental toxicology 2018 Sep;37(9):944-952
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Jin H, Liu P, Wu Y, Meng X, Wu M, Han J, Tan X
Cancer science 2018 Sep;109(9):2946-2956
Cancer science 2018 Sep;109(9):2946-2956
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Batool S, Joseph TP, Hussain M, Vuai MS, Khinsar KH, Din SRU, Padhiar AA, Zhong M, Ning A, Zhang W, Cao J, Huang M
International journal of molecular sciences 2018 Sep 30;19(10)
International journal of molecular sciences 2018 Sep 30;19(10)
Predictive and prognostic value of Matrix metalloproteinase (MMP) - 9 in neoadjuvant chemotherapy for triple-negative breast cancer patients.
Wang RX, Chen S, Huang L, Shao ZM
BMC cancer 2018 Sep 21;18(1):909
BMC cancer 2018 Sep 21;18(1):909
Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma.
Wang X, Li H, Lu X, Wen C, Huo Z, Shi M, Tang X, Chen H, Peng C, Fang Y, Deng X, Shen B
Cell death & disease 2018 Sep 20;9(10):940
Cell death & disease 2018 Sep 20;9(10):940
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, Song E, Song Y
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Chemical research in toxicology 2018 Sep 17;31(9):954-963
α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injury.
Mei Z, Tian X, Chen J, Wang Y, Yao Y, Li X, Yang C, Zhang S, Xie C
Oncology reports 2018 Oct;40(4):2287-2297
Oncology reports 2018 Oct;40(4):2287-2297
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Xia Y, Yu B, Ma C, Tu Y, Zhai L, Yang Y, Liu D, Liu Y, Wu H, Dan H, You P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
Zhou X, Yan T, Huang C, Xu Z, Wang L, Jiang E, Wang H, Chen Y, Liu K, Shao Z, Shang Z
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
Zhou X, Xu L, Xu J, Wu J, Kirk TB, Ma D, Xue W
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
He XX, Shi LL, Qiu MJ, Li QT, Wang MM, Xiong ZF, Yang SL
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Arsenic Trioxide Suppressed Migration and Angiogenesis by Targeting FOXO3a in Gastric Cancer Cells.
Zhang L, Liu L, Zhan S, Chen L, Wang Y, Zhang Y, Du J, Wu Y, Gu L
International journal of molecular sciences 2018 Nov 24;19(12)
International journal of molecular sciences 2018 Nov 24;19(12)
IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling.
Wang R, Deng X, Yuan C, Xin H, Liu G, Zhu Y, Jiang X, Wang C
International journal of molecular sciences 2018 Nov 16;19(11)
International journal of molecular sciences 2018 Nov 16;19(11)
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Yuan Q, Chen X, Han Y, Lei T, Wu Q, Yu X, Wang L, Fan Z, Wang S
International journal of cancer 2018 Nov 1;143(9):2319-2330
International journal of cancer 2018 Nov 1;143(9):2319-2330
Exosomes with Highly Angiogenic Potential for Possible Use in Pulp Regeneration.
Xian X, Gong Q, Li C, Guo B, Jiang H
Journal of endodontics 2018 May;44(5):751-758
Journal of endodontics 2018 May;44(5):751-758
Combined application of Embelin and tumor necrosis factor-related apoptosis-inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase-induced apoptosis.
Qian H, Chen Y, Huang T, Liu T, Li X, Jiang G, Zhang W, Cheng S, Li P
Oncology letters 2018 May;15(5):6931-6940
Oncology letters 2018 May;15(5):6931-6940
TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma.
Moriwaki K, Ayani Y, Kuwabara H, Terada T, Kawata R, Asahi M
Oncotarget 2018 May 18;9(38):25225-25243
Oncotarget 2018 May 18;9(38):25225-25243
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
Wang L, Zhao Y, Wu Q, Guan Y, Wu X
Molecular medicine reports 2018 Mar;17(3):4299-4306
Molecular medicine reports 2018 Mar;17(3):4299-4306
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Yu L, Wang S, Lin X, Lu Y, Gu P
Molecular medicine reports 2018 Mar;17(3):3972-3978
Molecular medicine reports 2018 Mar;17(3):3972-3978
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Liu S, Liu B
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Wang AL, Li Y, Zhao Q, Fan LQ
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular Mechanisms Underlying the Inhibitory Effects of Qingzaojiufei Decoction on Tumor Growth in Lewis Lung Carcinoma.
Xie B, Xie X, Rao B, Liu S, Liu H
Integrative cancer therapies 2018 Jun;17(2):467-476
Integrative cancer therapies 2018 Jun;17(2):467-476
Ginkgetin ameliorates experimental atherosclerosis in rats.
Lian N, Tong J, Li W, Wu J, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:510-516
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:510-516
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Ci Y, Zhang Y, Liu Y, Lu S, Cao J, Li H, Zhang J, Huang Z, Zhu X, Gao J, Han M
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122.
Chai FN, Ma WY, Zhang J, Xu HS, Li YF, Zhou QD, Li XG, Ye XL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1002-1011
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1002-1011
Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice.
Nasiri-Ansari Ν, Dimitriadis GK, Agrogiannis G, Perrea D, Kostakis ID, Kaltsas G, Papavassiliou AG, Randeva HS, Kassi E
Cardiovascular diabetology 2018 Jul 26;17(1):106
Cardiovascular diabetology 2018 Jul 26;17(1):106
Cinobufacini inhibits epithelial-mesenchymal transition of human hepatocellular carcinoma cells through c-Met/ERK signaling pathway.
Qi F, Wang J, Zhao L, Cai P, Tang W, Wang Z
Bioscience trends 2018 Jul 17;12(3):291-297
Bioscience trends 2018 Jul 17;12(3):291-297
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.
Zhang J, Liu L, Wang J, Ren B, Zhang L, Li W
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Journal of ethnopharmacology 2018 Jul 15;221:91-99
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, Wei X, Chen C, Liu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Liu W, Liu X, Wang L, Zhu B, Zhang C, Jia W, Zhu H, Liu X, Zhong M, Xie D, Liu Y, Li S, Shi J, Lin J, Xia X, Jiang X, Ren C
Oncology reports 2018 Jan;39(1):45-52
Oncology reports 2018 Jan;39(1):45-52
Anticancer Efficacy of Targeted Shikonin Liposomes Modified with RGD in Breast Cancer Cells.
Wen X, Li J, Cai D, Yue L, Wang Q, Zhou L, Fan L, Sun J, Wu Y
Molecules (Basel, Switzerland) 2018 Jan 29;23(2)
Molecules (Basel, Switzerland) 2018 Jan 29;23(2)
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, Qi W, Yang H
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Interference of Notch 1 inhibits the proliferation and invasion of breast cancer cells: Involvement of the β‑catenin signaling pathway.
Lai XX, Li G, Lin B, Yang H
Molecular medicine reports 2018 Feb;17(2):2472-2478
Molecular medicine reports 2018 Feb;17(2):2472-2478
MEG3 inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells.
Shi Y, Lv C, Shi L, Tu G
Oncology letters 2018 Feb;15(2):1917-1923
Oncology letters 2018 Feb;15(2):1917-1923
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
Liu M, Zhang X, Long C, Xu H, Cheng X, Chang J, Zhang C, Zhang C, Wang X
RSC advances 2018 Feb 23;8(16):8910-8919
RSC advances 2018 Feb 23;8(16):8910-8919
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Zhang L, Chen C, Duanmu J, Wu Y, Tao J, Yang A, Yin X, Xiong B, Gu J, Li C, Liu Z
International immunopharmacology 2018 Dec;65:429-437
International immunopharmacology 2018 Dec;65:429-437
Identification of COL1A1 as an invasion‑related gene in malignant astrocytoma.
Sun S, Wang Y, Wu Y, Gao Y, Li Q, Abdulrahman AA, Liu XF, Ji GQ, Gao J, Li L, Wan FP, Li YQ, Gao DS
International journal of oncology 2018 Dec;53(6):2542-2554
International journal of oncology 2018 Dec;53(6):2542-2554
Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Zhang X, Liu S, Weng X, Wu T, Yu L, Xu Y, Guo J
Journal of molecular and cellular cardiology 2018 Dec;125:6-17
Journal of molecular and cellular cardiology 2018 Dec;125:6-17
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Wang T, Wang D, Zhang Y, Zhang J, Sun X, Wu Y, Wang S, Zhang Y, Xu L, Kong Q, Gao Y, Wu Y, Liu F, Liu S, Zhang Y, Lei T, Liu H
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation.
Yan P, Tang H, Chen X, Ji S, Jin W, Zhang J, Shen J, Deng H, Zhao X, Shen Q, Huang H
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection.
Rojas-Quintero J, Wang X, Tipper J, Burkett PR, Zuñiga J, Ashtekar AR, Polverino F, Rout A, Yambayev I, Hernández C, Jimenez L, Ramírez G, Harrod KS, Owen CA
JCI insight 2018 Dec 20;3(24)
JCI insight 2018 Dec 20;3(24)
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.
Chen E, Yang F, He H, Li Q, Zhang W, Xing J, Zhu Z, Jiang J, Wang H, Zhao X, Liu R, Lei L, Dong J, Pei Y, Yang Y, Pan J, Zhang P, Liu S, Du L, Zeng Y, Yang J
Molecular cancer 2018 Dec 20;17(1):176
Molecular cancer 2018 Dec 20;17(1):176
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Tian YS, Chen KC, Zulkefli ND, Maner RS, Hsieh CL
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Zhang HR, Lai SY, Huang LJ, Zhang ZF, Liu J, Zheng SR, Ding K, Bai X, Zhou JY
Gynecologic oncology 2018 Apr;149(1):188-197
Gynecologic oncology 2018 Apr;149(1):188-197
Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
Li N, Zhang L, Li Q, Du Y, Liu H, Liu Y, Xiong W
Reproduction (Cambridge, England) 2018 Apr 1;157(4):371-381
Reproduction (Cambridge, England) 2018 Apr 1;157(4):371-381
Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma.
Guo Y, Peng Y, Gao D, Zhang M, Yang W, Linghu E, Herman JG, Fuks F, Dong G, Guo M
Clinical epigenetics 2017;9:116
Clinical epigenetics 2017;9:116
Macrophages Polarized by Expression of ToxoGRA15(II) Inhibit Growth of Hepatic Carcinoma.
Li Y, Poppoe F, Chen J, Yu L, Deng F, Luo Q, Xu Y, Cai Y, Shen J
Frontiers in immunology 2017;8:137
Frontiers in immunology 2017;8:137
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Shen Y, Guo D, Weng L, Wang S, Ma Z, Yang Y, Wang P, Wang J, Cai Z
Oncoimmunology 2017;6(12):e1362527
Oncoimmunology 2017;6(12):e1362527
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Cai Y, Zhang M, Qiu X, Wang B, Fu Y, Zeng J, Bai J, Yang G
Disease markers 2017;2017:8276939
Disease markers 2017;2017:8276939
Ethanol Extract of Root of Prunus persica Inhibited the Growth of Liver Cancer Cell HepG2 by Inducing Cell Cycle Arrest and Migration Suppression.
Shen H, Wang H, Wang L, Wang L, Zhu M, Ming Y, Zhao S, Fan J, Lai EY
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8231936
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8231936
Corticosteroids effects on LPS-induced rat inflammatory keratocyte cell model.
Yan H, Wang Y, Shen S, Wu Z, Wan P
PloS one 2017;12(4):e0176639
PloS one 2017;12(4):e0176639
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells.
Liu Y, Tang ZG, Yang JQ, Zhou Y, Meng LH, Wang H, Li CL
OncoTargets and therapy 2017;10:4023-4028
OncoTargets and therapy 2017;10:4023-4028
Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer.
Yan C, Jiang Y, Wan Y, Zhang L, Liu J, Zhou S, Cheng W
OncoTargets and therapy 2017;10:1993-2002
OncoTargets and therapy 2017;10:1993-2002
CircHIPK3 sponges miR-558 to suppress heparanase expression in bladder cancer cells.
Li Y, Zheng F, Xiao X, Xie F, Tao D, Huang C, Liu D, Wang M, Wang L, Zeng F, Jiang G
EMBO reports 2017 Sep;18(9):1646-1659
EMBO reports 2017 Sep;18(9):1646-1659
Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1.
Jin H, Wang C, Jin G, Ruan H, Gu D, Wei L, Wang H, Wang N, Arunachalam E, Zhang Y, Deng X, Yang C, Xiong Y, Feng H, Yao M, Fang J, Gu J, Cong W, Qin W
Gastroenterology 2017 Sep;153(3):799-811.e33
Gastroenterology 2017 Sep;153(3):799-811.e33
Adipose Progenitor Cell Secretion of GM-CSF and MMP9 Promotes a Stromal and Immunological Microenvironment That Supports Breast Cancer Progression.
Reggiani F, Labanca V, Mancuso P, Rabascio C, Talarico G, Orecchioni S, Manconi A, Bertolini F
Cancer research 2017 Sep 15;77(18):5169-5182
Cancer research 2017 Sep 15;77(18):5169-5182
BMAL1 facilitates trophoblast migration and invasion via SP1-DNMT1/DAB2IP pathway in recurrent spontaneous abortion.
Li S, Zhai J, Liu J, Hong Y, Zhao W, Zhao A, Sun K, Du Y, Chen ZJ
Oncotarget 2017 Oct 27;8(52):89451-89464
Oncotarget 2017 Oct 27;8(52):89451-89464
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells.
Wang J, Wu Y, Guo J, Fei X, Yu L, Ma S
Oncotarget 2017 Oct 10;8(47):81880-81891
Oncotarget 2017 Oct 10;8(47):81880-81891
LOX-1 is involved in IL-1β production and extracellular matrix breakdown in dental peri-implantitis.
Che C, Liu J, Ma L, Xu H, Bai N, Zhang Q
International immunopharmacology 2017 Nov;52:127-135
International immunopharmacology 2017 Nov;52:127-135
PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds.
Zhang J, Yang X, Wang H, Zhao B, Wu X, Su L, Xie S, Wang Y, Li J, Liu J, Liu M, Han F, He T, Zhang W, Tao K, Hu D
International journal of molecular medicine 2017 Nov;40(5):1335-1346
International journal of molecular medicine 2017 Nov;40(5):1335-1346
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Li H, Qiu Z, Li F, Wang C
Oncology letters 2017 Nov;14(5):5865-5870
Oncology letters 2017 Nov;14(5):5865-5870
Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation.
Qiao L, Zheng J, Jin X, Wei G, Wang G, Sun X, Li X
Oncology letters 2017 Nov;14(5):5831-5838
Oncology letters 2017 Nov;14(5):5831-5838
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
Xue TF, Ding X, Ji J, Yan H, Huang JY, Guo XD, Yang J, Sun XL
Journal of pharmacological sciences 2017 Nov;135(3):105-113
Journal of pharmacological sciences 2017 Nov;135(3):105-113
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Li Y, Fang S, Li Y, Zhu YH, Yuan YF, Guan XY
Cancer research 2017 Nov 1;77(21):5831-5845
Cancer research 2017 Nov 1;77(21):5831-5845
HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice.
Luo H, Li Z, Ge H, Mei D, Zhao L, Jiang L, Geng C, Li Q, Yao X, Cao J
Chemico-biological interactions 2017 Nov 1;277:1-7
Chemico-biological interactions 2017 Nov 1;277:1-7
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Zhang X, Fu L, Xue D, Zhang X, Hao F, Xie L, He J, Gai J, Liu Y, Xu H, Li Q, Wang E
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Clinical Significance and Tumor-Suppressive Function of miR-516b in Nonsmall Cell Lung Cancer.
Zhu J, Zhang Y, Yang X, Jin L
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Cancer biotherapy & radiopharmaceuticals 2017 May;32(4):115-123
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.
Que Z, Wang P, Hu Y, Xue Y, Liu X, Qu C, Ma J, Liu Y
Pharmacological research 2017 May;119:72-88
Pharmacological research 2017 May;119:72-88
Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.
Zhao H, Zhang L, Zhang Y, Zhao L, Wan Q, Wang B, Bu X, Wan M, Shen C
Oncotarget 2017 May 30;8(22):36383-36398
Oncotarget 2017 May 30;8(22):36383-36398
MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2.
Wang Y, Du J, Niu X, Fu N, Wang R, Zhang Y, Zhao S, Sun D, Nan Y
Cell death & disease 2017 May 18;8(5):e2792
Cell death & disease 2017 May 18;8(5):e2792
Synergistic inhibition of migration and invasion of breast cancer cells by dual docetaxel/quercetin-loaded nanoparticles via Akt/MMP-9 pathway.
Li J, Zhang J, Wang Y, Liang X, Wusiman Z, Yin Y, Shen Q
International journal of pharmaceutics 2017 May 15;523(1):300-309
International journal of pharmaceutics 2017 May 15;523(1):300-309
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Yang W, Yang S, Zhang M, Gao D, He T, Guo M
Genes & cancer 2017 Mar;8(3-4):528-535
Genes & cancer 2017 Mar;8(3-4):528-535
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
Lin ZK, Liu J, Jiang GQ, Tan G, Gong P, Luo HF, Li HM, Du J, Ning Z, Xin Y, Wang ZY
Oncology reports 2017 Mar;37(3):1611-1618
Oncology reports 2017 Mar;37(3):1611-1618
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.
Xie R, Wang J, Liu X, Wu L, Zhang H, Tang W, Li Y, Xiang L, Peng Y, Huang X, Bai Y, Liu G, Li A, Wang Y, Chen Y, Ren Y, Li G, Gong W, Liu S, Wang J
Scientific reports 2017 Jun 16;7(1):3709
Scientific reports 2017 Jun 16;7(1):3709
MicroRNA-203 inhibits proliferation and invasion, and promotes apoptosis of osteosarcoma cells by targeting Runt-related transcription factor 2.
Lin W, Zhu X, Yang S, Chen X, Wang L, Huang Z, Ding Y, Huang L, Lv C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:1075-1084
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:1075-1084
S100P is associated with proliferation and migration in nasopharyngeal carcinoma.
Liu Y, Wang C, Shan X, Wu J, Liu H, Liu H, Zhang J, Xu W, Sha Z, He J, Fan J
Oncology letters 2017 Jul;14(1):525-532
Oncology letters 2017 Jul;14(1):525-532
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
Xu B, Ye MH, Lv SG, Wang QX, Wu MJ, Xiao B, Kang CS, Zhu XG
Oncotarget 2017 Jul 4;8(27):43953-43966
Oncotarget 2017 Jul 4;8(27):43953-43966
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Su WC, Lin YF, Yu XP, Wang YX, Lin XD, Su QZ, Shen DY, Chen QX
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Wang Y, Wu N, Pang B, Tong D, Sun D, Sun H, Zhang C, Sun W, Meng X, Bai J, Chen F, Geng J, Fu S, Jin Y
Oncotarget 2017 Jul 18;8(29):47931-47942
Oncotarget 2017 Jul 18;8(29):47931-47942
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.
Xiang J, Fu X, Ran W, Wang Z
Oncogenesis 2017 Jan 9;6(1):e284
Oncogenesis 2017 Jan 9;6(1):e284
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca(2+)-calcineurin-NFATc1 signaling pathway.
Zhang J, Xu H, Han Z, Chen P, Yu Q, Lei Y, Li Z, Zhao M, Tian J
Biochemical and biophysical research communications 2017 Jan 8;482(2):289-295
Biochemical and biophysical research communications 2017 Jan 8;482(2):289-295
Pinus massoniana bark extract inhibits migration of the lung cancer A549 cell line.
Mao P, Zhang E, Chen Y, Liu L, Rong D, Liu Q, Li W
Oncology letters 2017 Feb;13(2):1019-1023
Oncology letters 2017 Feb;13(2):1019-1023
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J
British journal of cancer 2017 Feb 28;116(5):626-633
British journal of cancer 2017 Feb 28;116(5):626-633
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, Cao R, Tian W
Molecular medicine reports 2017 Dec;16(6):8729-8734
Molecular medicine reports 2017 Dec;16(6):8729-8734
Effects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy.
Chen B, He T, Xing Y, Cao T
Experimental and therapeutic medicine 2017 Dec;14(6):6022-6026
Experimental and therapeutic medicine 2017 Dec;14(6):6022-6026
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Wang H, Deng L, Cai M, Zhuang H, Zhu L, Hao Y, Gao J, Liu J, Li X, Lin B
Oncotarget 2017 Dec 8;8(64):108093-108107
Oncotarget 2017 Dec 8;8(64):108093-108107
Effects of quercetin on proliferation and migration of human glioblastoma U251 cells.
Liu Y, Tang ZG, Lin Y, Qu XG, Lv W, Wang GB, Li CL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Aug;92:33-38
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Aug;92:33-38
18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Wang S, Shen Y, Qiu R, Chen Z, Chen Z, Chen W
International journal of oncology 2017 Aug;51(2):615-624
International journal of oncology 2017 Aug;51(2):615-624
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Li X, Yang Z, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
International journal of molecular medicine 2017 Aug;40(2):311-318
International journal of molecular medicine 2017 Aug;40(2):311-318
Sesamin protects SH-SY5Y cells against mechanical stretch injury and promoting cell survival.
Xu Z, Liu Y, Yang D, Yuan F, Ding J, Chen H, Tian H
BMC neuroscience 2017 Aug 7;18(1):57
BMC neuroscience 2017 Aug 7;18(1):57
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Zou Y, Qiu G, Jiang L, Cai Z, Sun W, Hu H, Lu C, Jin W, Hu G
Oncotarget 2017 Aug 29;8(35):58231-58246
Oncotarget 2017 Aug 29;8(35):58231-58246
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Fan S, Liao Y, Liu C, Huang Q, Liang H, Ai B, Fu S, Zhou S
Oncotarget 2017 Aug 22;8(34):56443-56459
Oncotarget 2017 Aug 22;8(34):56443-56459
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Wang Y, Chu Y, Yue B, Ma X, Zhang G, Xiang H, Liu Y, Wang T, Wu X, Chen B
Oncotarget 2017 Apr 4;8(14):23803-23816
Oncotarget 2017 Apr 4;8(14):23803-23816
Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis.
Li C, Miao R, Liu S, Wan Y, Zhang S, Deng Y, Bi J, Qu K, Zhang J, Liu C
Oncotarget 2017 Apr 25;8(17):28683-28695
Oncotarget 2017 Apr 25;8(17):28683-28695
The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
Wang J, Zhang Y, Wei H, Zhang X, Wu Y, Gong A, Xia Y, Wang W, Xu M
Oncotarget 2017 Apr 11;8(15):24978-24987
Oncotarget 2017 Apr 11;8(15):24978-24987
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
Zhao L, Zheng XY
OncoTargets and therapy 2016;9:4505-16
OncoTargets and therapy 2016;9:4505-16
Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages.
Wu Z, Ruan Y, Chang J, Li B, Ren W
American journal of translational research 2016;8(3):1426-36
American journal of translational research 2016;8(3):1426-36
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, Xu J, Che L, Chen X, Sluijter JP, Das S, Cretoiu D, Xu B, Zhong J, Xiao J, Li X
Theranostics 2016;6(12):2068-2083
Theranostics 2016;6(12):2068-2083
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
HOX Antisense lincRNA HOXA-AS2 Promotes Tumorigenesis of Hepatocellular Carcinoma.
Wang F, Yang H, Deng Z, Su Y, Fang Q, Yin Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):287-296
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):287-296
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Li J, Chen K, Li S, Feng J, Liu T, Wang F, Zhang R, Xu S, Zhou Y, Zhou S, Xia Y, Lu J, Zhou Y, Guo C
Drug design, development and therapy 2016;10:619-30
Drug design, development and therapy 2016;10:619-30
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Chen S, Sun KX, Feng MX, Sang XB, Liu BL, Zhao Y
Drug design, development and therapy 2016;10:1225-32
Drug design, development and therapy 2016;10:1225-32
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Huang D, Wang S, Wang A, Chen X, Zhang H
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma.
Xie N, Wang C, Zhuang Z, Hou J, Liu X, Wu Y, Liu H, Huang H
Oncotarget 2016 Oct 4;7(40):65744-65757
Oncotarget 2016 Oct 4;7(40):65744-65757
Knockdown of High Mobility Group-Box 3 (HMGB3) Expression Inhibits Proliferation, Reduces Migration, and Affects Chemosensitivity in Gastric Cancer Cells.
Guo S, Wang Y, Gao Y, Zhang Y, Chen M, Xu M, Hu L, Jing Y, Jing F, Li C, Wang Q, Zhu Z
Medical science monitor : international medical journal of experimental and clinical research 2016 Oct 24;22:3951-3960
Medical science monitor : international medical journal of experimental and clinical research 2016 Oct 24;22:3951-3960
Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling.
Cao B, Yang W, Jin Y, Zhang M, He T, Zhan Q, Herman JG, Zhong G, Guo M
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Nov;11(11):1912-1926
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Nov;11(11):1912-1926
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
Hu K, Tian Y, Du Y, Huang L, Chen J, Li N, Liu W, Liang Z, Zhao L
International journal of oncology 2016 May;48(5):2166-74
International journal of oncology 2016 May;48(5):2166-74
TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells.
Huang YK, Fan XG, Qiu F
International journal of molecular sciences 2016 May 3;17(5)
International journal of molecular sciences 2016 May 3;17(5)
miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2.
Zhou YW, Zhang H, Duan CJ, Gao Y, Cheng YD, He D, Li R, Zhang CF
Oncotarget 2016 May 24;7(21):30730-47
Oncotarget 2016 May 24;7(21):30730-47
Effect of AQP9 Expression in Androgen-Independent Prostate Cancer Cell PC3.
Chen Q, Zhu L, Zheng B, Wang J, Song X, Zheng W, Wang L, Yang D, Wang J
International journal of molecular sciences 2016 May 14;17(5)
International journal of molecular sciences 2016 May 14;17(5)
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Wang J, Wu Q, Zhang LH, Zhao YX, Wu X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
Si L, Zheng L, Xu L, Yin L, Han X, Qi Y, Xu Y, Wang C, Peng J
European journal of pharmacology 2016 Mar 5;774:105-17
European journal of pharmacology 2016 Mar 5;774:105-17
High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway.
Chen W, Zhou P, Li X
International journal of molecular medicine 2016 Jun;37(6):1551-7
International journal of molecular medicine 2016 Jun;37(6):1551-7
Evidence for a role of GPRC6A in prostate cancer metastasis based on case-control and in vitro analyses.
Liu M, Zhao YY, Yang F, Wang JY, Shi XH, Zhu XQ, Xu Y, Wei D, Sun L, Zhang YG, Yang K, Qu YC, Wang X, Liang SY, Chen X, Zhao CX, Zhu L, Tang L, Zheng CG, Yang Z
European review for medical and pharmacological sciences 2016 Jun;20(11):2235-48
European review for medical and pharmacological sciences 2016 Jun;20(11):2235-48
Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing.
Yang Q, Qi X, Dang Y, Li Y, Song X, Hao X
BMC cardiovascular disorders 2016 Jun 24;16(1):142
BMC cardiovascular disorders 2016 Jun 24;16(1):142
Clinical Significance and Roles in Angiogenesis of Circulating Microparticles in Oral Cancer.
Ren JG, Zhang W, Liu B, Man QW, Xiong XP, Li C, Zhu JY, Wang WM, Jia J, Sun ZJ, Zhang WF, Chen G, Zhao YF
Journal of dental research 2016 Jul;95(8):860-7
Journal of dental research 2016 Jul;95(8):860-7
MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway.
Lv C, Hao Y, Tu G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9333-42
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jul;37(7):9333-42
Persisting and Increasing Neutrophil Infiltration Associates with Gastric Carcinogenesis and E-cadherin Downregulation.
Fu H, Ma Y, Yang M, Zhang C, Huang H, Xia Y, Lu L, Jin W, Cui D
Scientific reports 2016 Jul 14;6:29762
Scientific reports 2016 Jul 14;6:29762
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.
Zhao M, Fan J, Liu Y, Yu Y, Xu J, Wen Q, Zhang J, Fu S, Wang B, Xiang L, Feng J, Wu J, Yang L
International journal of oncology 2016 Feb;48(2):756-64
International journal of oncology 2016 Feb;48(2):756-64
MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.
Zeng CY, Zhan YS, Huang J, Chen YX
Molecular medicine reports 2016 Feb;13(2):1297-303
Molecular medicine reports 2016 Feb;13(2):1297-303
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Molecular cancer 2016 Feb 2;15:11
Molecular cancer 2016 Feb 2;15:11
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Yuan S, Wang L, Chen X, Fan B, Yuan Q, Zhang H, Yang D, Wang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1776-1782
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
Zhang WG, Li CF, Liu M, Chen XF, Shuai K, Kong X, Lv L, Mei ZC
Cancer letters 2016 Aug 10;378(2):111-9
Cancer letters 2016 Aug 10;378(2):111-9
DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis.
Tan C, Qiao F, Wei P, Chi Y, Wang W, Ni S, Wang Q, Chen T, Sheng W, Du X, Wang L
Molecular carcinogenesis 2016 Apr;55(4):397-408
Molecular carcinogenesis 2016 Apr;55(4):397-408
MicroRNA-183 functions as the tumor suppressor via inhibiting cellular invasion and metastasis by targeting MMP-9 in cervical cancer.
Fan D, Wang Y, Qi P, Chen Y, Xu P, Yang X, Jin X, Tian X
Gynecologic oncology 2016 Apr;141(1):166-74
Gynecologic oncology 2016 Apr;141(1):166-74
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.
Xia ZX, Li ZX, Zhang M, Sun LM, Zhang QF, Qiu XS
Experimental and molecular pathology 2016 Apr;100(2):353-60
Experimental and molecular pathology 2016 Apr;100(2):353-60
MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells.
Yang T, He W, Cui F, Xia J, Zhou R, Wu Z, Zhao Y, Shi M
Oncotarget 2016 Apr 5;7(14):18085-94
Oncotarget 2016 Apr 5;7(14):18085-94
Selenium-substituted hydroxyapatite nanoparticles and their in vivo antitumor effect on hepatocellular carcinoma.
Yanhua W, Hao H, Li Y, Zhang S
Colloids and surfaces. B, Biointerfaces 2016 Apr 1;140:297-306
Colloids and surfaces. B, Biointerfaces 2016 Apr 1;140:297-306
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
Chu Y, Tang H, Guo Y, Guo J, Huang B, Fang F, Cai J, Wang Z
Experimental cell research 2015 Sep 10;337(1):16-27
Experimental cell research 2015 Sep 10;337(1):16-27
Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice.
Wang X, Dai W, Wang Y, Gu Q, Yang D, Zhang M
International journal of environmental research and public health 2015 Sep 1;12(9):10739-54
International journal of environmental research and public health 2015 Sep 1;12(9):10739-54
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
Ren L, Mendoza A, Zhu J, Briggs JW, Halsey C, Hong ES, Burkett SS, Morrow J, Lizardo MM, Osborne T, Li SQ, Luu HH, Meltzer P, Khanna C
Oncotarget 2015 Oct 6;6(30):29469-81
Oncotarget 2015 Oct 6;6(30):29469-81
GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.
Zhang Q, Zhuang J, Deng Y, Zhao X, Tang B, Yao D, Zhao W, Chang C, Lu Q, Chen W, Zhang S, Ji C, Cao L, Guo H
Oncotarget 2015 Oct 13;6(31):32177-92
Oncotarget 2015 Oct 13;6(31):32177-92
Gab1 regulates proliferation and migration through the PI3K/Akt signaling pathway in intrahepatic cholangiocarcinoma.
Sang H, Li T, Li H, Liu J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8367-77
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8367-77
Anti-metastatic effects of antrodan, the Antrodia cinnamomea mycelia glycoprotein, in lung carcinoma cells.
Fa KN, Yang CM, Chen PC, Lee YY, Chyau CC, Hu ML
International journal of biological macromolecules 2015 Mar;74:476-82
International journal of biological macromolecules 2015 Mar;74:476-82
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis.
Yang X, Zhang H, Wang J, Zhang Z, Li C
Journal of periodontal research 2015 Dec;50(6):748-57
Journal of periodontal research 2015 Dec;50(6):748-57
Protective effect of simvastatin on impaired intestine tight junction protein ZO-1 in a mouse model of Parkinson's disease.
Fang X, Xu RS
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2015 Dec;35(6):880-884
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2015 Dec;35(6):880-884
The co-expression of MMP-9 and Tenascin-C is significantly associated with the progression and prognosis of pancreatic cancer.
Xu Y, Li Z, Jiang P, Wu G, Chen K, Zhang X, Li X
Diagnostic pathology 2015 Dec 10;10:211
Diagnostic pathology 2015 Dec 10;10:211
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Hu Y, Lin X, Wang P, Xue YX, Li Z, Liu LB, Yu B, Feng TD, Liu YH
Journal of cellular physiology 2015 Aug;230(8):1713-28
Journal of cellular physiology 2015 Aug;230(8):1713-28
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.
Liu Z, Wei P, Yang Y, Cui W, Cao B, Tan C, Yu B, Bi R, Xia K, Chen W, Wang Y, Zhang Y, Du X, Zhou X
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1752-63
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1752-63
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer.
He D, Wang J, Zhang C, Shan B, Deng X, Li B, Zhou Y, Chen W, Hong J, Gao Y, Chen Z, Duan C
Molecular cancer 2015 Apr 1;14:73
Molecular cancer 2015 Apr 1;14:73
α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway.
Xu Q, Ma J, Lei J, Duan W, Sheng L, Chen X, Hu A, Wang Z, Wu Z, Wu E, Ma Q, Li X
BioMed research international 2014;2014:546353
BioMed research international 2014;2014:546353
Human umbilical cord mesenchymal stem cells promote carcinoma growth and lymph node metastasis when co-injected with esophageal carcinoma cells in nude mice.
Yang X, Li Z, Ma Y, Gao J, Liu S, Gao Y, Wang G
Cancer cell international 2014;14(1):93
Cancer cell international 2014;14(1):93
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway.
Xu Z, Liu D, Fan C, Luan L, Zhang X, Wang E
Molecular carcinogenesis 2014 Nov;53(11):917-25
Molecular carcinogenesis 2014 Nov;53(11):917-25
Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries.
Peng X, Li HX, Shao HJ, Li GW, Sun J, Xi YH, Li HZ, Wang XY, Wang LN, Bai SZ, Zhang WH, Zhang L, Yang GD, Wu LY, Wang R, Xu CQ
Molecular and cellular biochemistry 2014 Nov;396(1-2):87-98
Molecular and cellular biochemistry 2014 Nov;396(1-2):87-98
Rho GDP dissociation inhibitor beta promotes cell proliferation and invasion by modulating the AKT pathway in hepatocellular carcinoma.
Fang Y, Yi J, Lizhi L, Qiucheng C
DNA and cell biology 2014 Nov;33(11):781-6
DNA and cell biology 2014 Nov;33(11):781-6
Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling.
Gao F, Chambon P, Tellides G, Kong W, Zhang X, Li W
Biochemical and biophysical research communications 2014 Nov 7;454(1):245-50
Biochemical and biophysical research communications 2014 Nov 7;454(1):245-50
Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm.
Gao F, Chambon P, Offermanns S, Tellides G, Kong W, Zhang X, Li W
Biochemical and biophysical research communications 2014 Nov 7;454(1):137-43
Biochemical and biophysical research communications 2014 Nov 7;454(1):137-43
Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Wang X, Zuo D, Chen Y, Li W, Liu R, He Y, Ren L, Zhou L, Deng T, Wang X, Ying G, Ba Y
British journal of cancer 2014 Nov 11;111(10):1965-76
British journal of cancer 2014 Nov 11;111(10):1965-76
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Wen N, Wang Y, Wen L, Zhao SH, Ai ZH, Wang Y, Wu B, Lu HX, Yang H, Liu WC, Li Y
Journal of translational medicine 2014 May 20;12:134
Journal of translational medicine 2014 May 20;12:134
Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression.
Puolakkainen P, Koski A, Vainionpää S, Shen Z, Repo H, Kemppainen E, Mustonen H, Seppänen H
Medical oncology (Northwood, London, England) 2014 Mar;31(3):884
Medical oncology (Northwood, London, England) 2014 Mar;31(3):884
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Wu Q, He J, Mei W, Zhang Z, Wu X, Sun F
Metallomics : integrated biometal science 2014 Dec;6(12):2204-12
Metallomics : integrated biometal science 2014 Dec;6(12):2204-12
Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration.
Zhang W, Tu G, Lv C, Long J, Cong L, Han Y
Biochemical and biophysical research communications 2014 Aug 22;451(2):222-8
Biochemical and biophysical research communications 2014 Aug 22;451(2):222-8
Up-regulated isocitrate dehydrogenase 1 suppresses proliferation, migration and invasion in osteosarcoma: in vitro and in vivo.
Hu X, Liu Y, Qin C, Pan Z, Luo J, Yu A, Cheng Z
Cancer letters 2014 Apr 28;346(1):114-21
Cancer letters 2014 Apr 28;346(1):114-21
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Song Y, Gong K, Yan H, Hong W, Wang L, Wu Y, Li W, Li W, Cao Z
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma.
Sang H, Li T, Li H, Liu J
PloS one 2013;8(11):e81347
PloS one 2013;8(11):e81347
Proteasome inhibitor MG132 enhances TRAIL-induced apoptosis and inhibits invasion of human osteosarcoma OS732 cells.
Li X, Huang T, Jiang G, Gong W, Qian H, Zou C
Biochemical and biophysical research communications 2013 Sep 20;439(2):179-86
Biochemical and biophysical research communications 2013 Sep 20;439(2):179-86
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Zhang S, Qi Y, Xu Y, Han X, Peng J, Liu K, Sun CK
Neurochemistry international 2013 Nov;63(5):522-32
Neurochemistry international 2013 Nov;63(5):522-32
Interferon regulatory factor (IRF)-1 and IRF-2 are associated with prognosis and tumor invasion in HCC.
Yi Y, Wu H, Gao Q, He HW, Li YW, Cai XY, Wang JX, Zhou J, Cheng YF, Jin JJ, Fan J, Qiu SJ
Annals of surgical oncology 2013 Jan;20(1):267-76
Annals of surgical oncology 2013 Jan;20(1):267-76
Chemical composition of total flavonoids from Salvia chinensia Benth and their pro-apoptotic effect on hepatocellular carcinoma cells: potential roles of suppressing cellular NF-κB signaling.
Xiang M, Su H, Hu Y, Hu Y, Yang T, Shu G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:420-6
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:420-6
Inhibition of cell migration by ouabain in the A549 human lung cancer cell line.
Liu N, Li Y, Su S, Wang N, Wang H, Li J
Oncology letters 2013 Aug;6(2):475-479
Oncology letters 2013 Aug;6(2):475-479
A case of pulmonary capillary hemangiomatosis with pulmonary fibrosis associated with MMP-9 related pulmonary remodeling.
Sakashita N, Motooka Y, Suganuma M, Ohnishi K, Fujiwara Y, Nakagawa T, Ichiyasu H, Takeya M
Pathology international 2011 May;61(5):306-12
Pathology international 2011 May;61(5):306-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10375-2-AP(MMP9 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MMP9 (IP:10375-2-AP, 3ug; Detection:10375-2-AP 1:300) with Jurkat cells lysate 4000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MMP9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MMP9. This antibody recognizes human, mouse, rat, zebrafish antigen. The MMP9 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
