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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- H00026054-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00026054-M01, RRID:AB_2270177
- Product name
- Mouse Monoclonal SENP6 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. SENP6 - SUMO1/sentrin specific protease 6
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression of SUMO/Sentrin-Specific Peptidase 6 To Facilitate Establishment of Latency.
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.
Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Lin X, Sun R, Zhang F, Gao Y, Bin L, Lan K
Journal of virology 2017 Sep 1;91(17)
Journal of virology 2017 Sep 1;91(17)
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.
Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W
Genome medicine 2014;6(9):68
Genome medicine 2014;6(9):68
Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.
Liu X, Chen W, Wang Q, Li L, Wang C
PLoS pathogens 2013;9(6):e1003480
PLoS pathogens 2013;9(6):e1003480
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.
Dou H, Huang C, Singh M, Carpenter PB, Yeh ET
Molecular cell 2010 Aug 13;39(3):333-45
Molecular cell 2010 Aug 13;39(3):333-45
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Han Y, Huang C, Sun X, Xiang B, Wang M, Yeh ET, Chen Y, Li H, Shi G, Cang H, Sun Y, Wang J, Wang W, Gao F, Yi J
The Journal of biological chemistry 2010 Apr 23;285(17):12906-15
The Journal of biological chemistry 2010 Apr 23;285(17):12906-15
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SENP6 Antibody (4B7) [H00026054-M01] - SENP6 monoclonal antibody (M01), clone 4B7 Analysis of SENP6 expression in IMR-32.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: SENP6 Antibody (4B7) [H00026054-M01] - Detection limit for recombinant GST tagged SENP6 is approximately 0.03ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SENP6 Antibody (4B7) [H00026054-M01] - Analysis of monoclonal antibody to SENP6 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: SENP6 Antibody (4B7) [H00026054-M01] - Staining with senp6 antibody and negative controls, acquisition by FACS. Image from verified customer review.
