Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations [0]
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- Product number
- 66351-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- COX2/ Cyclooxygenase 2/ PTGS2 antibody
- Antibody type
- Monoclonal
- Description
- COX2/ Cyclooxygenase 2/ PTGS2 antibody (Cat. #66351-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3G2B9
- Vial size
- 20ul, 150ul
Submitted references Reduction of tyrosine hydroxylase expression and increase of α-synuclein in the substantia nigra in a rat model of benign prostatic hyperplasia.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Multifunctional MnO2-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Pelvic lipomatosis with cystitis glandularis managed with cyclooxygenase-2 inhibitor: A case report.
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson's Disease.
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies.
Seo MH, Jin BR, Kim HJ, An HJ, Yeo S
Neuroscience letters 2022 Jan 19;769:136386
Neuroscience letters 2022 Jan 19;769:136386
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Li Y, Chandra TP, Song X, Nie L, Liu M, Yi J, Zheng X, Chu C, Yang J
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512
Oxidative medicine and cellular longevity 2021;2021:7292512
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study.
Hu X, Li R, Sun M, Kong Y, Zhu H, Wang F, Wan Q
Journal of inflammation research 2021;14:1403-1414
Journal of inflammation research 2021;14:1403-1414
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
Yin L, Shi C, Zhang Z, Wang W, Li M
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Tan X, Guo W, Peng Z, Gu C, Xiang P, Tu Y, Fei H, Liu X, Lu Y, Li M, Wang H, Luo Y, Yang J
Biochemical pharmacology 2021 Oct;192:114694
Biochemical pharmacology 2021 Oct;192:114694
Multifunctional MnO2-based nanoplatform-induced ferroptosis and apoptosis for synergetic chemoradiotherapy.
Li X, Wang Q, Yu S, Zhang M, Liu X, Deng G, Liu Y, Wu S
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Nanomedicine (London, England) 2021 Nov;16(26):2343-2361
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Zhang R, Zhang Y, Xin X, Huang G, Zhang N, Zeng Q, Tang L, Attaribo T, Lee KS, Jin BR, Gui Z
Journal of natural products 2021 May 28;84(5):1534-1543
Journal of natural products 2021 May 28;84(5):1534-1543
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Ma ZY, Song XQ, Hu JJ, Wang DB, Ding XJ, Liu RP, Dai ML, Meng FY, Xu JY
Biochemical pharmacology 2021 Jun;188:114523
Biochemical pharmacology 2021 Jun;188:114523
Pelvic lipomatosis with cystitis glandularis managed with cyclooxygenase-2 inhibitor: A case report.
Mo LC, Piao SZ, Zheng HH, Hong T, Feng Q, Ke M
World journal of clinical cases 2021 Jun 16;9(17):4373-4380
World journal of clinical cases 2021 Jun 16;9(17):4373-4380
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
Liu Z, Lv X, Yang B, Qin Q, Song E, Song Y
Chemosphere 2021 Feb;264(Pt 1):128413
Chemosphere 2021 Feb;264(Pt 1):128413
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Hong S, Dia VP, Zhong Q
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson's Disease.
Li W, Goshima Y, Ohshima T
Neurochemical research 2020 Oct;45(10):2286-2301
Neurochemical research 2020 Oct;45(10):2286-2301
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Wu CC, Chen YR, Lu DH, Hsu LH, Yang KC, Sumi S
Regenerative therapy 2020 Jun;14:177-183
Regenerative therapy 2020 Jun;14:177-183
Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.
Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H
The Annals of thoracic surgery 2020 Jul;110(1):40-49
The Annals of thoracic surgery 2020 Jul;110(1):40-49
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Shao Z, Lu J, Zhang C, Zeng G, Chen B, Liang H, Wu A, Zhang X, Wang X
Food & function 2020 Dec 1;11(12):10864-10875
Food & function 2020 Dec 1;11(12):10864-10875
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Wang W, Yang R, Zhang M, Li J, Peng J, Xu M, Zhao Y, Li H, Pan X
Inflammation 2020 Aug;43(4):1312-1322
Inflammation 2020 Aug;43(4):1312-1322
Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies.
Pacheu-Grau D, Bareth B, Dudek J, Juris L, Vögtle FN, Wissel M, Leary SC, Dennerlein S, Rehling P, Deckers M
Cell metabolism 2015 Jun 2;21(6):823-33
Cell metabolism 2015 Jun 2;21(6):823-33
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